CN113015495A - 用于治疗心脏疾病的加热蒸汽消融系统和方法 - Google Patents
用于治疗心脏疾病的加热蒸汽消融系统和方法 Download PDFInfo
- Publication number
- CN113015495A CN113015495A CN201980074339.7A CN201980074339A CN113015495A CN 113015495 A CN113015495 A CN 113015495A CN 201980074339 A CN201980074339 A CN 201980074339A CN 113015495 A CN113015495 A CN 113015495A
- Authority
- CN
- China
- Prior art keywords
- balloon
- catheter
- ablation
- outer balloon
- lumen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002679 ablation Methods 0.000 title claims description 540
- 238000010438 heat treatment Methods 0.000 title claims description 125
- 238000000034 method Methods 0.000 title description 126
- 208000019622 heart disease Diseases 0.000 title description 6
- 239000012530 fluid Substances 0.000 claims abstract description 186
- 210000005003 heart tissue Anatomy 0.000 claims abstract description 156
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 233
- 210000003492 pulmonary vein Anatomy 0.000 claims description 202
- 238000013507 mapping Methods 0.000 claims description 170
- 238000004891 communication Methods 0.000 claims description 75
- 206010003119 arrhythmia Diseases 0.000 claims description 49
- 230000006793 arrhythmia Effects 0.000 claims description 31
- 230000007246 mechanism Effects 0.000 claims description 20
- 239000012267 brine Substances 0.000 claims description 11
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 claims description 11
- 235000014443 Pyrus communis Nutrition 0.000 claims description 5
- 230000001419 dependent effect Effects 0.000 claims description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 3
- 238000013153 catheter ablation Methods 0.000 abstract description 66
- 210000001519 tissue Anatomy 0.000 description 140
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 120
- 239000003570 air Substances 0.000 description 117
- 239000012809 cooling fluid Substances 0.000 description 91
- 229910002092 carbon dioxide Inorganic materials 0.000 description 87
- 210000005248 left atrial appendage Anatomy 0.000 description 85
- 230000009977 dual effect Effects 0.000 description 60
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 59
- 238000011282 treatment Methods 0.000 description 59
- 239000011780 sodium chloride Substances 0.000 description 58
- 239000001569 carbon dioxide Substances 0.000 description 56
- 210000005246 left atrium Anatomy 0.000 description 51
- 239000000463 material Substances 0.000 description 50
- 238000002347 injection Methods 0.000 description 49
- 239000007924 injection Substances 0.000 description 49
- 239000003795 chemical substances by application Substances 0.000 description 46
- 210000002216 heart Anatomy 0.000 description 41
- 239000008280 blood Substances 0.000 description 35
- 210000004369 blood Anatomy 0.000 description 35
- 238000001816 cooling Methods 0.000 description 29
- 238000010793 Steam injection (oil industry) Methods 0.000 description 28
- 239000002826 coolant Substances 0.000 description 25
- 230000017531 blood circulation Effects 0.000 description 24
- 210000003739 neck Anatomy 0.000 description 21
- 210000000056 organ Anatomy 0.000 description 21
- 230000008569 process Effects 0.000 description 20
- 206010003658 Atrial Fibrillation Diseases 0.000 description 18
- 230000000747 cardiac effect Effects 0.000 description 18
- 238000002955 isolation Methods 0.000 description 18
- 230000001225 therapeutic effect Effects 0.000 description 18
- 150000001875 compounds Chemical class 0.000 description 16
- 230000000694 effects Effects 0.000 description 16
- 230000003902 lesion Effects 0.000 description 15
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 14
- 230000001746 atrial effect Effects 0.000 description 14
- 229960002897 heparin Drugs 0.000 description 14
- 229920000669 heparin Polymers 0.000 description 14
- 210000003484 anatomy Anatomy 0.000 description 13
- 238000012544 monitoring process Methods 0.000 description 13
- 229920000139 polyethylene terephthalate Polymers 0.000 description 12
- 238000012546 transfer Methods 0.000 description 12
- 206010028980 Neoplasm Diseases 0.000 description 11
- 238000013459 approach Methods 0.000 description 11
- 238000009413 insulation Methods 0.000 description 11
- 229910052751 metal Inorganic materials 0.000 description 11
- 239000002184 metal Substances 0.000 description 11
- 239000000758 substrate Substances 0.000 description 11
- 239000011248 coating agent Substances 0.000 description 10
- 238000000576 coating method Methods 0.000 description 10
- 239000008223 sterile water Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- 230000006870 function Effects 0.000 description 9
- 210000002837 heart atrium Anatomy 0.000 description 9
- 230000001965 increasing effect Effects 0.000 description 9
- 230000009467 reduction Effects 0.000 description 9
- 240000007817 Olea europaea Species 0.000 description 8
- 238000009833 condensation Methods 0.000 description 8
- 230000005494 condensation Effects 0.000 description 8
- 230000007717 exclusion Effects 0.000 description 8
- 230000000977 initiatory effect Effects 0.000 description 8
- 230000015654 memory Effects 0.000 description 8
- 230000033764 rhythmic process Effects 0.000 description 8
- 206010068690 Pulmonary vein occlusion Diseases 0.000 description 7
- 210000001367 artery Anatomy 0.000 description 7
- 230000008859 change Effects 0.000 description 7
- 230000006378 damage Effects 0.000 description 7
- 238000001802 infusion Methods 0.000 description 7
- 239000003550 marker Substances 0.000 description 7
- 230000007704 transition Effects 0.000 description 7
- 238000010317 ablation therapy Methods 0.000 description 6
- 230000004888 barrier function Effects 0.000 description 6
- 210000001174 endocardium Anatomy 0.000 description 6
- 238000002594 fluoroscopy Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 210000001147 pulmonary artery Anatomy 0.000 description 6
- 230000002829 reductive effect Effects 0.000 description 6
- 238000010186 staining Methods 0.000 description 6
- 206010003130 Arrhythmia supraventricular Diseases 0.000 description 5
- 229920002614 Polyether block amide Polymers 0.000 description 5
- 241000282898 Sus scrofa Species 0.000 description 5
- 238000011298 ablation treatment Methods 0.000 description 5
- 238000005452 bending Methods 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 230000003028 elevating effect Effects 0.000 description 5
- -1 for example Substances 0.000 description 5
- 238000003384 imaging method Methods 0.000 description 5
- 238000002844 melting Methods 0.000 description 5
- 230000008018 melting Effects 0.000 description 5
- 239000003607 modifier Substances 0.000 description 5
- 210000004165 myocardium Anatomy 0.000 description 5
- 230000002763 arrhythmic effect Effects 0.000 description 4
- 239000012298 atmosphere Substances 0.000 description 4
- 239000004067 bulking agent Substances 0.000 description 4
- 238000005345 coagulation Methods 0.000 description 4
- 230000015271 coagulation Effects 0.000 description 4
- 238000004520 electroporation Methods 0.000 description 4
- 239000012212 insulator Substances 0.000 description 4
- 230000002262 irrigation Effects 0.000 description 4
- 238000003973 irrigation Methods 0.000 description 4
- 239000004816 latex Substances 0.000 description 4
- 229920000126 latex Polymers 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- VPRUMANMDWQMNF-UHFFFAOYSA-N phenylethane boronic acid Chemical class OB(O)CCC1=CC=CC=C1 VPRUMANMDWQMNF-UHFFFAOYSA-N 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 238000009834 vaporization Methods 0.000 description 4
- 230000008016 vaporization Effects 0.000 description 4
- 230000002792 vascular Effects 0.000 description 4
- 238000012800 visualization Methods 0.000 description 4
- 208000004248 Familial Primary Pulmonary Hypertension Diseases 0.000 description 3
- 208000020875 Idiopathic pulmonary arterial hypertension Diseases 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 208000031481 Pathologic Constriction Diseases 0.000 description 3
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 3
- 238000003491 array Methods 0.000 description 3
- 210000001008 atrial appendage Anatomy 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000008602 contraction Effects 0.000 description 3
- 239000002872 contrast media Substances 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000010339 dilation Effects 0.000 description 3
- 238000001839 endoscopy Methods 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 description 3
- 230000037361 pathway Effects 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000012217 radiopharmaceutical Substances 0.000 description 3
- 229940121896 radiopharmaceutical Drugs 0.000 description 3
- 230000002799 radiopharmaceutical effect Effects 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000002441 reversible effect Effects 0.000 description 3
- 210000005245 right atrium Anatomy 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000008467 tissue growth Effects 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000023514 Barrett esophagus Diseases 0.000 description 2
- 208000023665 Barrett oesophagus Diseases 0.000 description 2
- 208000020446 Cardiac disease Diseases 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 2
- 239000002033 PVDF binder Substances 0.000 description 2
- 239000004696 Poly ether ether ketone Substances 0.000 description 2
- 239000004642 Polyimide Substances 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 206010042600 Supraventricular arrhythmias Diseases 0.000 description 2
- 206010047281 Ventricular arrhythmia Diseases 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 239000003416 antiarrhythmic agent Substances 0.000 description 2
- 229910052788 barium Inorganic materials 0.000 description 2
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 238000010292 electrical insulation Methods 0.000 description 2
- 230000010102 embolization Effects 0.000 description 2
- 238000002674 endoscopic surgery Methods 0.000 description 2
- 210000003238 esophagus Anatomy 0.000 description 2
- 210000003191 femoral vein Anatomy 0.000 description 2
- 239000003302 ferromagnetic material Substances 0.000 description 2
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000005291 magnetic effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000001314 paroxysmal effect Effects 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 210000003105 phrenic nerve Anatomy 0.000 description 2
- 230000035479 physiological effects, processes and functions Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920002530 polyetherether ketone Polymers 0.000 description 2
- 229920001721 polyimide Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000036262 stenosis Effects 0.000 description 2
- 208000037804 stenosis Diseases 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000003685 thermal hair damage Effects 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- KKJUPNGICOCCDW-UHFFFAOYSA-N 7-N,N-Dimethylamino-1,2,3,4,5-pentathiocyclooctane Chemical compound CN(C)C1CSSSSSC1 KKJUPNGICOCCDW-UHFFFAOYSA-N 0.000 description 1
- 208000012260 Accidental injury Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000028389 Nerve injury Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 208000037062 Polyps Diseases 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000004433 Thermoplastic polyurethane Substances 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 150000001241 acetals Chemical class 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 210000003157 atrial septum Anatomy 0.000 description 1
- 108091008698 baroreceptors Proteins 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000036471 bradycardia Effects 0.000 description 1
- JYYOBHFYCIDXHH-UHFFFAOYSA-N carbonic acid;hydrate Chemical compound O.OC(O)=O JYYOBHFYCIDXHH-UHFFFAOYSA-N 0.000 description 1
- 238000010000 carbonizing Methods 0.000 description 1
- 210000004413 cardiac myocyte Anatomy 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000005524 ceramic coating Methods 0.000 description 1
- 230000000739 chaotic effect Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000002638 denervation Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 210000000620 electrically active cell Anatomy 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 210000002767 hepatic artery Anatomy 0.000 description 1
- 210000002989 hepatic vein Anatomy 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011900 installation process Methods 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000007433 macroscopic evaluation Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000007431 microscopic evaluation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000008764 nerve damage Effects 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 230000001936 parietal effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 229920003223 poly(pyromellitimide-1,4-diphenyl ether) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 210000003240 portal vein Anatomy 0.000 description 1
- 238000010248 power generation Methods 0.000 description 1
- 210000001774 pressoreceptor Anatomy 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 208000002815 pulmonary hypertension Diseases 0.000 description 1
- 230000036593 pulmonary vascular resistance Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 210000002796 renal vein Anatomy 0.000 description 1
- 210000005077 saccule Anatomy 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000005549 size reduction Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000008400 supply water Substances 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 239000004557 technical material Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 229920006344 thermoplastic copolyester Polymers 0.000 description 1
- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
- 229920006346 thermoplastic polyester elastomer Polymers 0.000 description 1
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 231100000216 vascular lesion Toxicity 0.000 description 1
- 208000003663 ventricular fibrillation Diseases 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
- A61B2018/00232—Balloons having an irregular shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
- A61B2018/0025—Multiple balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
- A61B2018/0025—Multiple balloons
- A61B2018/00255—Multiple balloons arranged one inside another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
- A61B2018/00375—Ostium, e.g. ostium of pulmonary vein or artery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B2018/044—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B2018/044—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid
- A61B2018/046—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid in liquid form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B2018/044—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid
- A61B2018/048—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating the surgical action being effected by a circulating hot fluid in gaseous form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Otolaryngology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862729777P | 2018-09-11 | 2018-09-11 | |
US62/729,777 | 2018-09-11 | ||
US201962844222P | 2019-05-07 | 2019-05-07 | |
US62/844,222 | 2019-05-07 | ||
PCT/US2019/050662 WO2020056031A1 (en) | 2018-09-11 | 2019-09-11 | Heated vapor ablation systems and methods for treating cardiac conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113015495A true CN113015495A (zh) | 2021-06-22 |
Family
ID=69778152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201980074339.7A Pending CN113015495A (zh) | 2018-09-11 | 2019-09-11 | 用于治疗心脏疾病的加热蒸汽消融系统和方法 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP3849448A4 (ja) |
JP (1) | JP2022511318A (ja) |
CN (1) | CN113015495A (ja) |
AU (1) | AU2019338398A1 (ja) |
WO (1) | WO2020056031A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114469324A (zh) * | 2022-01-26 | 2022-05-13 | 中国医学科学院阜外医院 | 射频消融导管及射频消融系统 |
CN115105759A (zh) * | 2022-07-12 | 2022-09-27 | 四川大学华西医院 | 一种利用放射源的心肌病理组织致快速心律失常治疗导管 |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11819229B2 (en) | 2019-06-19 | 2023-11-21 | Boston Scientific Scimed, Inc. | Balloon surface photoacoustic pressure wave generation to disrupt vascular lesions |
US11717139B2 (en) | 2019-06-19 | 2023-08-08 | Bolt Medical, Inc. | Plasma creation via nonaqueous optical breakdown of laser pulse energy for breakup of vascular calcium |
US11660427B2 (en) | 2019-06-24 | 2023-05-30 | Boston Scientific Scimed, Inc. | Superheating system for inertial impulse generation to disrupt vascular lesions |
US11517713B2 (en) | 2019-06-26 | 2022-12-06 | Boston Scientific Scimed, Inc. | Light guide protection structures for plasma system to disrupt vascular lesions |
US11583339B2 (en) | 2019-10-31 | 2023-02-21 | Bolt Medical, Inc. | Asymmetrical balloon for intravascular lithotripsy device and method |
US11672599B2 (en) | 2020-03-09 | 2023-06-13 | Bolt Medical, Inc. | Acoustic performance monitoring system and method within intravascular lithotripsy device |
US20210290286A1 (en) | 2020-03-18 | 2021-09-23 | Bolt Medical, Inc. | Optical analyzer assembly and method for intravascular lithotripsy device |
US11707323B2 (en) | 2020-04-03 | 2023-07-25 | Bolt Medical, Inc. | Electrical analyzer assembly for intravascular lithotripsy device |
US12016610B2 (en) | 2020-12-11 | 2024-06-25 | Bolt Medical, Inc. | Catheter system for valvuloplasty procedure |
US11672585B2 (en) | 2021-01-12 | 2023-06-13 | Bolt Medical, Inc. | Balloon assembly for valvuloplasty catheter system |
CN112998844B (zh) * | 2021-02-05 | 2021-12-21 | 上海睿刀医疗科技有限公司 | 一种球囊电极导管 |
WO2022216488A1 (en) * | 2021-04-06 | 2022-10-13 | Bolt Medical, Inc. | Intravascular lithotripsy balloon |
US11648057B2 (en) | 2021-05-10 | 2023-05-16 | Bolt Medical, Inc. | Optical analyzer assembly with safety shutdown system for intravascular lithotripsy device |
US11806075B2 (en) | 2021-06-07 | 2023-11-07 | Bolt Medical, Inc. | Active alignment system and method for laser optical coupling |
CN113926061B (zh) * | 2021-11-18 | 2023-04-07 | 苏州海宇新辰医疗科技有限公司 | 球囊导管 |
US11839391B2 (en) | 2021-12-14 | 2023-12-12 | Bolt Medical, Inc. | Optical emitter housing assembly for intravascular lithotripsy device |
US20240099769A1 (en) * | 2022-09-28 | 2024-03-28 | Virender K. Sharma | Methods and Systems for Thermal Enhancement of Electroporation |
CN116898558B (zh) * | 2023-06-26 | 2024-04-30 | 苏州海宇新辰医疗科技有限公司 | 一种心脏冷冻消融用球囊导管 |
CN116747013B (zh) * | 2023-06-30 | 2024-06-18 | 苏州海宇新辰医疗科技有限公司 | 一种双层消融球囊导管 |
CN117752404B (zh) * | 2024-02-22 | 2024-05-07 | 四川锦江电子医疗器械科技股份有限公司 | 一种心脏电生理标测和消融导管 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6911028B2 (en) * | 1998-10-28 | 2005-06-28 | John H. Shadduck | Medical instrument working end and method for endoluminal treatments |
CN106102816A (zh) * | 2014-01-14 | 2016-11-09 | 美敦力 | 具有流体注射元件的球囊导管 |
US20160354140A1 (en) * | 2008-10-06 | 2016-12-08 | Virender K. Sharma | Induction-Based Micro-Volume Heating System |
US20170367755A1 (en) * | 2008-10-06 | 2017-12-28 | Santa Anna Tech Llc | Ablation Catheter with Integrated Cooling |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9433457B2 (en) * | 2000-12-09 | 2016-09-06 | Tsunami Medtech, Llc | Medical instruments and techniques for thermally-mediated therapies |
US7727228B2 (en) | 2004-03-23 | 2010-06-01 | Medtronic Cryocath Lp | Method and apparatus for inflating and deflating balloon catheters |
US7794455B2 (en) | 2005-04-29 | 2010-09-14 | Medtronic Cryocath Lp | Wide area ablation of myocardial tissue |
US7727191B2 (en) | 2005-05-13 | 2010-06-01 | Medtronic Cryocath Lp | Compliant balloon catheter |
WO2007001981A2 (en) | 2005-06-20 | 2007-01-04 | Ablation Frontiers | Ablation catheter |
CA2664738C (en) | 2006-09-29 | 2017-03-07 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
US9561068B2 (en) | 2008-10-06 | 2017-02-07 | Virender K. Sharma | Method and apparatus for tissue ablation |
US9561066B2 (en) | 2008-10-06 | 2017-02-07 | Virender K. Sharma | Method and apparatus for tissue ablation |
JP2013132364A (ja) * | 2011-12-26 | 2013-07-08 | Nippon Erekuteru:Kk | バルーンカテーテル |
EP3964151A3 (en) | 2013-01-17 | 2022-03-30 | Virender K. Sharma | Apparatus for tissue ablation |
WO2018089773A1 (en) * | 2016-11-10 | 2018-05-17 | Fractyl Laboratories, Inc. | Systems, devices, and methods for performing medical procedures in the intestine |
-
2019
- 2019-09-11 AU AU2019338398A patent/AU2019338398A1/en active Pending
- 2019-09-11 WO PCT/US2019/050662 patent/WO2020056031A1/en unknown
- 2019-09-11 JP JP2021514379A patent/JP2022511318A/ja active Pending
- 2019-09-11 EP EP19860901.8A patent/EP3849448A4/en active Pending
- 2019-09-11 CN CN201980074339.7A patent/CN113015495A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6911028B2 (en) * | 1998-10-28 | 2005-06-28 | John H. Shadduck | Medical instrument working end and method for endoluminal treatments |
US20160354140A1 (en) * | 2008-10-06 | 2016-12-08 | Virender K. Sharma | Induction-Based Micro-Volume Heating System |
US20170367755A1 (en) * | 2008-10-06 | 2017-12-28 | Santa Anna Tech Llc | Ablation Catheter with Integrated Cooling |
CN106102816A (zh) * | 2014-01-14 | 2016-11-09 | 美敦力 | 具有流体注射元件的球囊导管 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114469324A (zh) * | 2022-01-26 | 2022-05-13 | 中国医学科学院阜外医院 | 射频消融导管及射频消融系统 |
CN114469324B (zh) * | 2022-01-26 | 2022-10-11 | 中国医学科学院阜外医院 | 射频消融导管及射频消融系统 |
CN115105759A (zh) * | 2022-07-12 | 2022-09-27 | 四川大学华西医院 | 一种利用放射源的心肌病理组织致快速心律失常治疗导管 |
Also Published As
Publication number | Publication date |
---|---|
EP3849448A1 (en) | 2021-07-21 |
EP3849448A4 (en) | 2022-06-15 |
JP2022511318A (ja) | 2022-01-31 |
WO2020056031A1 (en) | 2020-03-19 |
AU2019338398A1 (en) | 2021-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN113015495A (zh) | 用于治疗心脏疾病的加热蒸汽消融系统和方法 | |
US5423811A (en) | Method for RF ablation using cooled electrode | |
EP3094364B1 (en) | Balloon catheter with fluid injection elements | |
US7184827B1 (en) | Shrinkage of dilatations in the body | |
EP3119303B1 (en) | Shape changing ablation balloon | |
US6640120B1 (en) | Probe assembly for mapping and ablating pulmonary vein tissue and method of using same | |
US6605055B1 (en) | Balloon catheter with irrigation sheath | |
US8795271B2 (en) | Surgical probe for supporting inflatable therapeutic devices in contact with tissue in or around body orifice and within tumors | |
US11331140B2 (en) | Heated vapor ablation systems and methods for treating cardiac conditions | |
US8679105B2 (en) | Device and method for pulmonary vein isolation | |
EP3678570A1 (en) | Devices and methods for treating lung tumors | |
JP2000506751A (ja) | 切除による直線状の損傷を形成する装置 | |
EP3763314A1 (en) | Systems, devices and methods for treating lung tumors | |
US20150045787A1 (en) | Electrosurgical device and method | |
WO2019051274A2 (en) | DEVICES FOR THE TREATMENT OF BRONCHOPULMONARY TUMORS | |
WO2019051251A1 (en) | DEVICES AND METHODS FOR THE TREATMENT OF LUNG CANCER | |
US20230355300A1 (en) | Systems, devices and methods for treating lung tumors with a robotically delivered catheter | |
WO2020185399A2 (en) | Systems, devices and methods for treating lung tumors | |
KR20230076822A (ko) | 폐 종양을 치료하기 위한 시스템 및 장치 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |