CN112996540A - 一种c-Met ADC在制备治疗c-Met激酶抑制剂耐药的疾病的药物中的用途 - Google Patents
一种c-Met ADC在制备治疗c-Met激酶抑制剂耐药的疾病的药物中的用途 Download PDFInfo
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Abstract
本公开提供一种c‑Met ADC在制备治疗c‑Met激酶抑制剂耐药的疾病的药物中的用途。具体而言，本公开提供了一种抗c‑Met抗体药物偶联物在在制备治疗c‑Met激酶抑制剂耐药的疾病的药物中的用途，特别是经c‑Met激酶抑制剂治疗后耐药的非小细胞肺癌，所述的抗c‑Met抗体药物偶联物如说明书所述。
Description
PCT国内申请，说明书已公开。
Claims (13)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018114525662 | 2018-11-30 | ||
| CN201811452566 | 2018-11-30 | ||
| PCT/CN2019/121943 WO2020108612A1 (zh) | 2018-11-30 | 2019-11-29 | 一种c-Met ADC在制备治疗c-Met激酶抑制剂耐药的疾病的药物中的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112996540A true CN112996540A (zh) | 2021-06-18 |
| CN112996540B CN112996540B (zh) | 2024-05-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201980072269.1A Active CN112996540B (zh) | 2018-11-30 | 2019-11-29 | 一种c-Met ADC在制备治疗c-Met激酶抑制剂耐药的疾病的药物中的用途 |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN112996540B (zh) |
| TW (1) | TW202033217A (zh) |
| WO (1) | WO2020108612A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116854694A (zh) * | 2023-07-04 | 2023-10-10 | 北京浦润奥生物科技有限责任公司 | [1,2,4]三唑[4,3-b]哒嗪化合物的晶型及其制备方法和应用 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230018454A (ko) * | 2020-09-01 | 2023-02-07 | 레메젠 코, 리미티드 | 항-c-Met 항체-약물 접합체 및 이의 용도 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016165580A1 (zh) * | 2015-04-17 | 2016-10-20 | 江苏恒瑞医药股份有限公司 | 抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途 |
-
2019
- 2019-11-29 TW TW108143716A patent/TW202033217A/zh unknown
- 2019-11-29 WO PCT/CN2019/121943 patent/WO2020108612A1/zh active Application Filing
- 2019-11-29 CN CN201980072269.1A patent/CN112996540B/zh active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016165580A1 (zh) * | 2015-04-17 | 2016-10-20 | 江苏恒瑞医药股份有限公司 | 抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途 |
Non-Patent Citations (1)
| Title |
|---|
| JIEYI WANG: "ABBV-399, a c-Met Antibody–Drug Conjugate that Targets Both MET–Amplified and c-Met– Overexpressing Tumors, Irrespective of MET Pathway Dependence", CLINICAL CANCER RESEARCH, vol. 23, no. 4, pages 992 - 100 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116854694A (zh) * | 2023-07-04 | 2023-10-10 | 北京浦润奥生物科技有限责任公司 | [1,2,4]三唑[4,3-b]哒嗪化合物的晶型及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020108612A1 (zh) | 2020-06-04 |
| CN112996540B (zh) | 2024-05-17 |
| TW202033217A (zh) | 2020-09-16 |
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