CN112972869A - Guide wire system for near infrared spectral analysis and pressure measurement - Google Patents
Guide wire system for near infrared spectral analysis and pressure measurement Download PDFInfo
- Publication number
- CN112972869A CN112972869A CN202110178461.8A CN202110178461A CN112972869A CN 112972869 A CN112972869 A CN 112972869A CN 202110178461 A CN202110178461 A CN 202110178461A CN 112972869 A CN112972869 A CN 112972869A
- Authority
- CN
- China
- Prior art keywords
- guide wire
- light
- sensor
- pressure measurement
- near infrared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
Abstract
The invention discloses a guide wire system for near infrared spectral analysis and pressure measurement, belonging to the field of diagnosis; the side wall of the near end of the guide wire is connected with the shell of the guide wire joint, and the sensor casing with the spectral analysis light exit hole on the side wall is arranged outside the far end of the guide wire; a sensor communication channel allowing the signal transmission optical fiber to pass through is arranged in the guide wire, and the proximal end of the signal transmission optical fiber is connected with the guide wire communication part of the guide wire joint; the sensor assembly for obtaining external pressure and image information is fixedly connected with the sensor casing, the light splitter in the sensor assembly is connected with the distal end of the signal transmission optical fiber, the color separation surface in the light splitter reflects the spectral analysis light and emits the spectral analysis light out of the spectral analysis light exit hole, and the pressure sensor is installed at the distal end of the light splitter. The combination of the optical pressure sensor and the optical near infrared spectrum analysis used by the invention utilizes the communication means of light as much as possible to achieve the effect of acquiring the focus information.
Description
Technical Field
The invention belongs to the technical field of diagnosis, and particularly relates to a guide wire system for near infrared spectroscopy analysis and pressure measurement.
Background
In the process of vessel interventional diagnosis and treatment, percutaneous puncture interventional treatment has the advantages of simple and convenient operation, less complication, less pain of patients, high success rate and the like. Currently, vascular interventional techniques have become an important diagnostic method and a major approach to interventional radiology. Interventional guide wires are widely used as important medical devices for guiding various catheters and interventional devices to reach target sites. Conventional guidewires are constructed from solid rods, made of stainless steel or nitinol, which provide good pushability and torqueability. After the interventional guide wire is pushed to the target part, various interventional instruments are usually sleeved on the guide wire through a certain tubular structure and pushed to the target part along the guide wire. One common type of interventional instrument is a diagnostic instrument, such as a blood pressure measuring instrument and various imaging catheters.
While vascular guidewires provide excellent guidance and support, pushing additional interventional instruments into the vessel is time consuming and increases the cost of the procedure. These interventional devices also require themselves to be very push, twist, compliant and hydrophilic due to the complex lesions and irregular bending of the patient's blood vessel. To reduce procedure time and reduce procedure costs, the prior art integrates pressure measurement sensors onto the vascular guidewire. In U.S. patent No. 6,167,763B 1, Tenerz et al disclose a solution for integrating an electronic pressure sensor into the tip of a vascular guidewire, thereby developing a pressure guidewire. In patent document CN 103328033B, belville discloses a technical solution of integrating an optical pressure sensor into the tip of a vascular guidewire, and develops an optical pressure guidewire. However, only pressure information can be acquired, and image information cannot be acquired at the same time, and the image of the blood vessel tissue is also an important source for providing information for the treatment of the blood vessel lesion.
In order to solve the problem, a guide wire system for near infrared spectrum analysis and pressure measurement is provided, and the used blood vessel guide wire can provide pressure information and image information in the blood vessel at the same time.
Disclosure of Invention
In view of the problems in the background art, the present invention provides a guide wire system for near infrared spectroscopy and pressure measurement, comprising: the device comprises a guide wire, a signal transmission optical fiber, a sensor casing, a sensor assembly, a guide wire joint, an adapter, a patient interaction unit and an image and pressure measurement engine, wherein the side wall of the near end of the guide wire is connected with the shell of the guide wire joint, and the sensor casing with a spectral analysis light exit hole on the side wall is arranged outside the far end of the guide wire; a sensor communication channel allowing the signal transmission optical fiber to pass through is arranged in the guide wire, and the proximal end of the signal transmission optical fiber is connected with the guide wire communication part of the guide wire joint; the guide wire communication part of the guide wire joint is sequentially connected with the adapter, the patient interaction unit and the imaging, image and pressure measurement engine;
a sensor assembly for obtaining ambient pressure and image information is secured within a sensor housing, the sensor assembly comprising: the optical fiber spectrometer comprises an optical splitter and a pressure sensor, wherein the optical splitter is connected with the distal end of a signal transmission optical fiber, a color separation surface in the optical splitter reflects spectral analysis light and emits the spectral analysis light out of a spectral analysis light emergent hole, and the pressure sensor is arranged at the distal end of the optical splitter; the distal end side of the sensor housing is provided with a pressure equalizing hole.
The signal transmission optical fiber is a multi-mode single-core optical fiber which is provided with a single-core light carrying area.
The signal transmission optical fiber is a multimode double-core optical fiber, a spacing block is additionally arranged between the distal end of the multimode double-core optical fiber and the sensor assembly, the multimode double-core optical fiber is provided with two light carrying areas which are an outer core light carrying area and an inner core light carrying area respectively, the outer core light carrying area is used for transmitting pressure measurement light for pressure measurement, and the inner core light carrying area is used for transmitting spectral analysis light for spectral analysis.
The outer diameter of the inner core light carrying area is 35-50 microns, the outer diameter of the outer core light carrying area is 62.5-90 microns, and the refractive index of the inner core light carrying area is 0.3-0.4% higher than that of the outer core light carrying area.
The outer cladding layer is arranged outside the outer core light carrying area, and the refractive index of the outer core light carrying area is 2.5% -3.5% higher than that of the outer cladding layer.
The radial periphery of the signal transmission optical fiber is provided with an outer cladding layer with low refractive index, and the outer side of the outer cladding layer is provided with a buffer layer with high refractive index.
The sensor housing has a length of between 2 mm and 4.5 mm, an outer diameter of 350 microns to 360 microns, and a wall thickness of 45 microns to 55 microns.
A spring head is mounted outside the distal end of the sensor housing.
The axial thickness of the light splitter is 100-250 microns, and the included angle between the color separation surface and the guide wire axis is 38-42 degrees.
A diaphragm which can deform along with the external pressure is arranged in the force sensor, and the diaphragm is perpendicular to the axial direction of the pressure sensor.
The invention has the beneficial effects that:
1. an optical pressure sensor is used to combine optical near infrared spectroscopy to form a small-sized optical combination probe for placement inside a vascular guidewire and delivery inside a blood vessel.
2. The combination of the optical pressure sensor and the optical near infrared spectrum analysis makes use of the communication means of light as much as possible to achieve the effect of acquiring the focus information.
3. The multimode double-core optical fiber is used, and the optical transmission characteristics of different fiber cores and cladding layers in a single optical fiber are effectively utilized in the transmission of optical signals, so that the cross-sectional area of an optical channel is minimum. The probe design and the utilization of the optical fiber effectively keep the smaller size of the blood vessel guide wire, and the guide wire is more in line with the use habit of an operator while providing more focus information.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment 1 of a guidewire system for near infrared spectroscopy and pressure measurement according to the present invention;
FIG. 2 is a schematic structural view of embodiment 1 of the present invention;
FIG. 3 is a schematic structural view of example 2 of the present invention;
FIG. 4 is a cross-sectional view of a multimode two-core optical fiber according to example 2 of the present invention;
FIG. 5 is a refractive index chart of a multimode two-core optical fiber in example 2 of the present invention.
Wherein:
1-guide wire, 2-signal transmission optical fiber, 3-sensor casing, 11-proximal part, 21-multimode single-core optical fiber, 22-multimode double-core optical fiber, 31-pressure sensor, 32-optical splitter, 33-pressure equalizing hole, 37-spectral analysis light exit hole, 104-spring head, 106-guide wire joint, 107-adapter, 108-patient interaction unit, 109-image and pressure measurement engine, 201-single-core light carrying area, 203-spectral analysis light, 204-pressure measurement light, 301-inner core light carrying area, 302-outer core light carrying area, 303-cladding, 304-buffer layer, 311-diaphragm and 321-color splitting surface.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
As shown in fig. 1 and 2, the embodiment 1 of the present invention includes: the device comprises a guide wire 1, a sensor casing 3, a sensor assembly, a signal transmission optical fiber 2, a spring head 104, a guide wire joint 106, an adapter 107, a patient interaction unit 108 and an image and pressure measurement engine 109, wherein the side wall of the proximal end of the guide wire 1 is connected with the shell of the guide wire joint 106, and the sensor casing 3 provided with a spectral analysis light exit hole 37 on the side wall is arranged outside the distal end of the guide wire 1; a sensor communication channel with a certain inner diameter is arranged in the guide wire 1, and the sensor communication channel allows the signal transmission optical fiber 2 to pass through; the proximal end of the signal transmission optical fiber 2 is connected with the guide wire communication part of the guide wire joint 106; the guide wire communication part of the guide wire joint 106 is sequentially connected with the adapter 107, the patient interaction unit 108 and the imaging, image and pressure measurement engine 109 to complete the processing of spectral analysis and pressure information;
a sensor assembly for obtaining the external pressure and image information is fixedly connected with the sensor housing 3, and the sensor assembly comprises: a beam splitter 32 and a pressure sensor 31, wherein the beam splitter 32 for refracting the spectral analysis light and transmitting the pressure measurement light is connected to the distal end of the signal transmission fiber 2, a dichroic surface 321 in the beam splitter 32 reflects the spectral analysis light 203 and emits it from a spectral analysis light exit hole 37, and the pressure sensor 31 is installed at the distal end of the beam splitter 32; the distal end side of the sensor jacket 3 is provided with a pressure equalizing hole 33 so that the pressure inside the inner cavity of the sensor jacket 3 is equalized with the pressure outside the sensor jacket 3 (guide wire 1).
In the present embodiment, the sensor jacket 3 has a length of between 2 mm and 4.5 mm, a wall thickness of 45 to 55 μm, and an outer diameter of 350 to 360 μm for the sensor jacket 3 and the guide wire 1.
In the present embodiment, the guide wire 1 has an outer diameter of 350 to 360 microns, the proximal end of the guide wire 1 is formed of a stainless steel hypotube, and the proximal end of the guide wire 1 and the guide wire connector 106 together are an operating portion; the middle part and the far end of the guide wire 1 are elastic metal shaft tubes; the main body of the guide wire 1 can not damage blood vessels and needs to be softer; thus, laser cutting, etching, or other methods of forming a cut pattern in the tube wall can be used to suitably reduce the stiffness of the tube wall while still transmitting torque and providing support.
In this embodiment, a spring tip 104 is mounted outside the distal end of the sensor housing 3 so that the guidewire does not cause injury to the blood vessel during advancement of the blood vessel.
In the present embodiment, the axial thickness of the beam splitter 32 is 100 to 250 micrometers; the included angle between the color separation surface 321 and the guide wire axis is 40 degrees, so that the incident angle of the spectrum analysis light 203 to the color separation surface is 50 degrees, the included angle between the emergent light and the guide wire axis is 80 degrees, and the phenomenon that the spectrum analysis light is subjected to mirror reflection on the surface of a tissue to reduce the signal-to-noise ratio is reduced. The beam splitter preferably uses a dichroic surface 321 optimized for a 50 ° angle of incidence; the dichroic surface 321 is preferably a mirror surface made by dielectric coating technology that reflects long wavelengths, i.e. ensures that at least 70%, preferably 95%, of the spectral analysis light 203 is reflected; at the same time it should be ensured that at least 70%, preferably 95%, of the pressure measuring light 204 is transmitted.
In this embodiment, the beam splitter 32 is preferably cylindrical to cover the circular spot of light propagating, the length of the cylinder being between 250 microns and 400 microns, the diameter being between 180 microns and 210 microns, and the material being silicon dioxide; the side of the beam splitter 32 is coated with an anti-reflection film of the spectrum analysis light 203 to improve the signal-to-noise ratio of the spectrum analysis.
In this embodiment, the pressure sensor 31 is a fabry-perot interference sensor, and a diaphragm 311 capable of deforming with the external pressure is disposed in the pressure sensor 31; the pressure sensor 31 has a regular hexagonal shape, and the diaphragm 311 is perpendicular to the axial direction of the pressure sensor 31.
The signal transmission optical fiber 2 shown in fig. 2 is a multimode single-core optical fiber 21, the multimode single-core optical fiber 21 has a single-core light-carrying region 201 which is a longitudinal continuation in the optical fiber, and the single-core light-carrying region 201 is used in common by a spectrum analysis light 203 (dotted line) for spectrum analysis and a pressure measurement light 204 (dotted line) for pressure measurement; in order to distinguish between the pressure measurement signal and the spectroscopic analysis signal, the spectroscopic analysis light 203 and the pressure measurement light 204 may use light whose wavelengths do not overlap.
In the present embodiment, the pressure measurement light 204 may use a visible light band in a range of 400 nm to 780 nm, and the spectral analysis light 203 may use a near infrared band in a range of 780 nm to 2526 nm; and the spectra of the spectral analysis light 203 and the pressure measurement light 204 are separated by at least 5 nanometers or more.
In operation, the guide wire connector 106 is operated to push the distal end of the guide wire 1, the sensor housing 3 and the spring head 104 into the corresponding positions in the blood vessel; and the guide wire joint 106 is rotated to drive the guide wire 1 and the sensor housing 3 to rotate, and the direction in which the spectral analysis light 203 is emitted (the spectral analysis light exit hole 37) is changed, so that different positions in the circumferential direction of the blood vessel can be imaged.
The signal light which is injected by the adapter 107 through the guide wire adapter 106 enters the single-core light-carrying area 201 through the optical splitter 32, and when the pressure measurement light 204 in the signal light passes through the optical splitter 32 from the single-core light-carrying area 201 of the multimode single-core optical fiber 21, the pressure measurement light is transmitted through the color separation surface 321 and reaches the pressure sensor 31, and the interference light which is reflected by the surface of the pressure sensor substrate and the diaphragm 311 to generate a pressure signal is returned from the single-core light-carrying area 201; meanwhile, when the spectral analysis light 203 passes through the spectroscope 32, it is reflected by the dichroic surface 321, emitted from the spectral analysis light exit hole 37, reflected by a blood vessel, and returned from the single-core light-carrying region 201 as interference light that carries an image signal.
The signal transmission fiber 2 shown in fig. 3 and 4 is a multimode dual-core fiber 22, a spacer 33 is additionally disposed between the distal end of the multimode dual-core fiber 22 and the sensor assembly, the multimode dual-core fiber 22 has two light-carrying regions, namely an outer core light-carrying region 302 and an inner core light-carrying region 301, which are two longitudinal continuations in the fiber; wherein the outer core light-carrying region 302 is mainly used to propagate pressure measurement light 204 for pressure measurement and the inner core light-carrying region 301 is mainly used to propagate spectral analysis light 203 for spectral analysis.
In the present embodiment, the axial thickness of the spacer 33 and the optical splitter 32 is 100 to 250 micrometers, and both materials are silicon dioxide;
in the present embodiment, the spacer 33, the spectroscope 32, and the pressure sensor 31 are fixed inside the sensor housing 3.
As shown in fig. 4, the multimode dual-core fiber 22 has different refractive index profiles such that the multimode dual-core fiber 22 has an inner core light-carrying region 301 and an outer core light-carrying region 302, and both cores can be multimode; a low-refractive-index outer cladding layer 303 is arranged at the radial periphery of the outer core light-carrying region 302, and a high-refractive-index buffer layer 304 is arranged outside the outer cladding layer 303; wherein the buffer layer 304 is a protective layer of the optical fiber, typically made of a material with a high attenuation coefficient; at the connection point of the signal transmission fiber 2, all or a portion of the buffer layer 304 is typically stripped to ensure that the buffer layer 304 does not carry any light.
It is easily understood that, in embodiment 1, the outer periphery of the single core light-carrying region 201 may also be provided with the over cladding 303 and the buffer layer 304 in this order, and therefore the arrangement of the over cladding 303 and the buffer layer 304 is applicable to all the signal transmission fibers 2.
In the present embodiment, in the multimode dual-core optical fiber 22, the outer diameter of the inner core light-carrying region 301 is 35 to 50 micrometers, the outer diameter of the outer core light-carrying region 302 is 62.5 to 90 micrometers, the outer diameter of the outer cladding 303 is 110 micrometers, and the outer diameter of the buffer layer is 130 micrometers; the refractive index of the inner core light-carrying region 301 is 0.3% to 0.4% higher than that of the outer core light-carrying region 302, and the refractive index of the outer core light-carrying region is 2.5% to 3.5% higher than that of the outer cladding 303; the buffer layer is made of polyimide.
In this embodiment, the adapter 107 is a double-clad fiber coupler, the double-core fiber coupler receives the signal light (the spectrum analysis light 203 and the pressure measurement light 204) from the signal transmission fiber 2, and since the two light beams are mainly concentrated in the inner core and the outer core respectively, the two light beams can be conveniently divided into two branches by using the double-core fiber coupler 501, and the two branches are both led to the image and pressure measurement engine 109 composed of the spectrum analysis engine and the pressure analysis engine through the interaction unit.
When the device works, the guide wire joint 106 is rotated to drive the guide wire 1 and the sensor casing 3 to rotate, and the direction of the spectral analysis light 203 of the spectral analysis is changed, so that images are generated at different positions on the circumferential direction of the blood vessel; the image is used for near infrared spectral analysis to diagnose lipid plaque in blood vessels; wherein the spectral analysis light 203 for spectral analysis enters the beam splitter 32 after passing through the spacer 33, and the beam splitter dichroic surface 321 of the beam splitter 32 can reflect at least most of the spectral analysis light 203, so that the spectral analysis light exits from the sensor housing 3 through the spectral analysis light exit hole 37; when the spectral analysis light is reflected by the blood vessel, the spectral analysis light exit hole 37 returns to the optical splitter 32 and passes through the spacer 33 along the original path, and finally returns to the image and pressure measurement engine 109 for spectral analysis by the inner core light-carrying region 301 in the signal transmission fiber 2.
Meanwhile, when the pressure measurement light 204 passes through the optical splitter 32 from the outer core light-carrying region 302 of the signal transmission fiber 2, it is transmitted through the dichroic surface 321 and reaches the pressure sensor 31; at this time, the pressure outside the sensor casing 3 is transmitted to the diaphragm 311 through the pressure equalizing hole 33, so that a pressure signal is formed and returned through the pressure sensor substrate surface and the diaphragm 311, and then returned to the signal transmission optical fiber 2 through the beam splitter 32 and the spacer 33, and most of the pressure enters the outer core light carrying area 302 and is finally transmitted to the image and pressure measurement engine 109 for image acquisition.
Claims (10)
1. A guidewire system for near infrared spectroscopy and pressure measurement, comprising: the device comprises a guide wire (1), a signal transmission optical fiber (2), a sensor casing (3), a sensor assembly, a guide wire joint (106), an adapter (107), a patient interaction unit (108) and an image and pressure measurement engine (109), wherein the side wall of the near end of the guide wire (1) is connected with the shell of the guide wire joint (106), and the sensor casing (3) with a spectrum analysis light emergent hole (37) formed in the side wall is installed outside the far end of the guide wire (1); a sensor communication channel allowing the signal transmission optical fiber (2) to pass through is arranged in the guide wire (1), and the proximal end of the signal transmission optical fiber (2) is connected with a guide wire communication part of the guide wire joint (106); the guide wire communication part of the guide wire joint (106) is sequentially connected with the adapter (107), the patient interaction unit (108) and the imaging, image and pressure measurement engine (109);
the sensor assembly is fixed in a sensor housing (3), the sensor assembly comprising: a beam splitter (32) and a pressure sensor (31), wherein the beam splitter (32) is connected with the distal end of the signal transmission fiber (2), a color separation surface (321) in the beam splitter (32) reflects the spectrum analysis light (203) and emits the spectrum analysis light from a spectrum analysis light exit hole (37), and the pressure sensor (31) is arranged at the distal end of the beam splitter (32); a pressure equalizing hole (33) is formed in the distal end side of the sensor housing (3).
2. The guide wire system for near infrared spectroscopic analysis and pressure measurement according to claim 1, wherein the signal transmission fiber (2) is a multimode single core fiber (21), and the multimode single core fiber (21) has a single core light carrying region (201).
3. The guide wire system for near infrared spectroscopic analysis and pressure measurement according to claim 1, wherein the signal transmission fiber (2) is a multimode two-core fiber (22), a spacer block (33) is additionally arranged between the distal end of the multimode two-core fiber (22) and the sensor assembly, and the multimode two-core fiber (22) has two light-carrying regions, namely an outer core light-carrying region (302) and an inner core light-carrying region (301), wherein the outer core light-carrying region (302) is used for transmitting pressure measurement light (204) for pressure measurement and the inner core light-carrying region (301) is used for transmitting spectral analysis light (203) for spectral analysis.
4. The guide wire system for near infrared spectroscopy and pressure measurement according to claim 3, wherein the outer diameter of the inner core light-carrying region (301) is 35 to 50 microns, the outer diameter of the outer core light-carrying region (302) is 62.5 to 90 microns, and the refractive index of the inner core light-carrying region (301) is 0.3 to 0.4% higher than the refractive index of the outer core light-carrying region (302).
5. The guide wire system for near infrared spectroscopy and pressure measurement according to any one of claims 3 or 4, wherein the outer core light-carrying region (302) is surrounded by an outer cladding (303), and the refractive index of the outer core light-carrying region is 2.5% to 3.5% higher than the refractive index of the outer cladding (303).
6. A guide wire system for near infrared spectroscopic analysis and pressure measurement according to one of claims 1 or 3, wherein the signal transmission fiber (2) is provided with a low refractive index outer cladding (303) at the radial periphery thereof, and a high refractive index buffer layer (304) is provided outside the outer cladding (303).
7. The guide wire system for near infrared spectroscopic analysis and pressure measurement according to claim 1, wherein the sensor housing (3) has a length of between 2 mm and 4.5 mm, an outer diameter of between 350 and 360 micrometers, and a wall thickness of between 45 and 55 micrometers.
8. Guide wire system for near infrared spectroscopic analysis and pressure measurement according to one of the claims 1 or 7, characterized in that a spring tip (104) is mounted outside the distal end of the sensor housing (3).
9. The guide wire system for near infrared spectroscopic analysis and pressure measurement according to claim 1, wherein the axial thickness of the beam splitter (32) is 100 to 250 microns, and the angle between the dichroic plane (321) and the guide wire axis is 38 to 42 °.
10. The guide wire system for near infrared spectroscopy and pressure measurement according to claim 1, wherein a diaphragm (311) capable of deforming with the external pressure is arranged in the force sensor (31), and the diaphragm (311) is perpendicular to the axial direction of the pressure sensor (31).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110178461.8A CN112972869A (en) | 2021-02-09 | 2021-02-09 | Guide wire system for near infrared spectral analysis and pressure measurement |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110178461.8A CN112972869A (en) | 2021-02-09 | 2021-02-09 | Guide wire system for near infrared spectral analysis and pressure measurement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112972869A true CN112972869A (en) | 2021-06-18 |
Family
ID=76392709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110178461.8A Pending CN112972869A (en) | 2021-02-09 | 2021-02-09 | Guide wire system for near infrared spectral analysis and pressure measurement |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112972869A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080285909A1 (en) * | 2007-04-20 | 2008-11-20 | Hansen Medical, Inc. | Optical fiber shape sensing systems |
| CN104739377A (en) * | 2015-03-20 | 2015-07-01 | 武汉阿格斯科技有限公司 | Device, system and method for simultaneously carrying out OCT imaging and pressure measurement in blood vessel |
| CN108348180A (en) * | 2015-09-04 | 2018-07-31 | 波士顿科学国际有限公司 | Pressure sensing seal wire |
| CN111202500A (en) * | 2019-03-26 | 2020-05-29 | 科特有限责任公司 | System and method for combined optical coherence tomography and pressure measurement |
| CN211751720U (en) * | 2020-01-17 | 2020-10-27 | 浙江医高医疗科技有限公司 | Visual lumen guide wire |
-
2021
- 2021-02-09 CN CN202110178461.8A patent/CN112972869A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080285909A1 (en) * | 2007-04-20 | 2008-11-20 | Hansen Medical, Inc. | Optical fiber shape sensing systems |
| CN104739377A (en) * | 2015-03-20 | 2015-07-01 | 武汉阿格斯科技有限公司 | Device, system and method for simultaneously carrying out OCT imaging and pressure measurement in blood vessel |
| CN108348180A (en) * | 2015-09-04 | 2018-07-31 | 波士顿科学国际有限公司 | Pressure sensing seal wire |
| CN111202500A (en) * | 2019-03-26 | 2020-05-29 | 科特有限责任公司 | System and method for combined optical coherence tomography and pressure measurement |
| CN211751720U (en) * | 2020-01-17 | 2020-10-27 | 浙江医高医疗科技有限公司 | Visual lumen guide wire |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7382949B2 (en) | Fiber-optic rotational device, optical system and method for imaging a sample | |
| US11058308B2 (en) | Intravascular pressure sensing devices and methods | |
| US9435956B1 (en) | Spectroscopic imaging probes, devices, and methods | |
| US20050165315A1 (en) | Side firing fiber optic array probe | |
| EP2329759B1 (en) | System and method for optical coherence imaging | |
| US6546272B1 (en) | Apparatus for in vivo imaging of the respiratory tract and other internal organs | |
| US10234676B1 (en) | Optical probes with reflecting components for astigmatism correction | |
| US10816789B2 (en) | Optical probes that include optical-correction components for astigmatism correction | |
| CN111202500B (en) | System and method for combined optical coherence tomography and pressure measurement | |
| WO2020072470A1 (en) | Overmolded distal optics for intraluminal optical probes | |
| US20190223700A1 (en) | Optical probes with optical-correction components | |
| US20210149101A1 (en) | Multicore Fiber Instrument with 3D-Printed Distal Optics | |
| JP2016165478A (en) | Optical fiber rotation device for image formation of sample, optical system and method | |
| US9128249B2 (en) | Optical probe and optical measuring method | |
| CN116138875B (en) | Interventional intravascular three-mode imaging, ablation and auxiliary temperature measurement integrated catheter | |
| CN112972869A (en) | Guide wire system for near infrared spectral analysis and pressure measurement | |
| AU2014200116B2 (en) | Intravascular optical coherence tomography system with pressure monitoring interface and accessories | |
| US20150219436A1 (en) | Optical probe and method of attaching optical probe | |
| US20120277580A1 (en) | System and method for diluting blood in a vessel | |
| CN117796743A (en) | Endoscopic probe and endoscopic system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210618 |
|
| RJ01 | Rejection of invention patent application after publication |