CN112933118A - 用于治疗眼睛的组合物和方法 - Google Patents

用于治疗眼睛的组合物和方法 Download PDF

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Publication number
CN112933118A
CN112933118A CN202011302835.4A CN202011302835A CN112933118A CN 112933118 A CN112933118 A CN 112933118A CN 202011302835 A CN202011302835 A CN 202011302835A CN 112933118 A CN112933118 A CN 112933118A
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CN
China
Prior art keywords
pichia
optionally
composition
extract
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011302835.4A
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English (en)
Chinese (zh)
Inventor
李丁文华
K·马哈迈德
R·伯尔萨
拜明岐
K·T·霍瓦
M·兰达瓦
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Johnson and Johnson Surgical Vision Inc
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Johnson and Johnson Consumer Companies LLC
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Filing date
Publication date
Priority claimed from US17/099,185 external-priority patent/US11969451B2/en
Application filed by Johnson and Johnson Consumer Companies LLC filed Critical Johnson and Johnson Consumer Companies LLC
Publication of CN112933118A publication Critical patent/CN112933118A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CN202011302835.4A 2019-11-19 2020-11-19 用于治疗眼睛的组合物和方法 Pending CN112933118A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962937473P 2019-11-19 2019-11-19
US201962937458P 2019-11-19 2019-11-19
US62/937458 2019-11-19
US62/937473 2019-11-19
US17/099,185 US11969451B2 (en) 2019-11-19 2020-11-16 Compositions and methods for treating the eye
US17/099185 2020-11-16

Publications (1)

Publication Number Publication Date
CN112933118A true CN112933118A (zh) 2021-06-11

Family

ID=75964158

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011302835.4A Pending CN112933118A (zh) 2019-11-19 2020-11-19 用于治疗眼睛的组合物和方法

Country Status (6)

Country Link
JP (1) JP2021080253A (ko)
KR (1) KR20210061297A (ko)
CN (1) CN112933118A (ko)
AU (2) AU2020273321A1 (ko)
BR (1) BR102020023560A8 (ko)
CA (1) CA3100032A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117268877A (zh) * 2023-11-21 2023-12-22 军科正源（北京）药物研究有限责任公司 检测人泪液中的神经生长因子的方法及其泪液的处理方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1883469A (zh) * 2006-05-26 2006-12-27 朱啟婉 一种含有维生素a和维生素e的眼用微乳及其制备方法
CN102994500A (zh) * 2008-10-22 2013-03-27 夸克医药公司 治疗眼部疾病的方法
CN106692029A (zh) * 2015-11-06 2017-05-24 强生消费者公司 局部用凝胶霜组合物
CN106890114A (zh) * 2015-12-17 2017-06-27 强生消费者公司 包含异常毕赤酵母和菊苣根提取物的局部用组合物
CN108210378A (zh) * 2016-12-12 2018-06-29 强生消费者公司 含有甘油和酵母提取物的局部用组合物
CN108697635A (zh) * 2016-02-08 2018-10-23 索夫特意大利公司 用于治疗与角膜-结膜表面改变有关的眼病的眼科组合物

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1883469A (zh) * 2006-05-26 2006-12-27 朱啟婉 一种含有维生素a和维生素e的眼用微乳及其制备方法
CN102994500A (zh) * 2008-10-22 2013-03-27 夸克医药公司 治疗眼部疾病的方法
CN104857526A (zh) * 2008-10-22 2015-08-26 夸克制药公司 治疗眼部疾病的方法
CN106692029A (zh) * 2015-11-06 2017-05-24 强生消费者公司 局部用凝胶霜组合物
CN106890114A (zh) * 2015-12-17 2017-06-27 强生消费者公司 包含异常毕赤酵母和菊苣根提取物的局部用组合物
CN108697635A (zh) * 2016-02-08 2018-10-23 索夫特意大利公司 用于治疗与角膜-结膜表面改变有关的眼病的眼科组合物
CN108210378A (zh) * 2016-12-12 2018-06-29 强生消费者公司 含有甘油和酵母提取物的局部用组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
顾其胜: "《眼手术并发症原因与处理》", 第二军医大学出版社, pages: 306 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117268877A (zh) * 2023-11-21 2023-12-22 军科正源（北京）药物研究有限责任公司 检测人泪液中的神经生长因子的方法及其泪液的处理方法
CN117268877B (zh) * 2023-11-21 2024-02-20 军科正源（北京）药物研究有限责任公司 检测人泪液中的神经生长因子的方法及其泪液的处理方法

Also Published As

Publication number Publication date
AU2020273321A1 (en) 2021-06-03
KR20210061297A (ko) 2021-05-27
AU2022263530A1 (en) 2022-12-08
BR102020023560A2 (pt) 2021-10-13
BR102020023560A8 (pt) 2023-02-07
CA3100032A1 (en) 2021-05-19
JP2021080253A (ja) 2021-05-27

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