CN112891439A - 一种复方谷精草液 - Google Patents
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Abstract
本发明提供了一种复方谷精草液，选用谷精草、生地、蝉蜕、防风、决明子、枸杞、黄连、柏仁子、木贼、菊花、熟地为原料，经水煎法提取而成，对假性近视眼的治疗具有较好效果，通过浸泡本发明的复方谷精草液的眼膜纸敷于眼睛周围，能使眼睛周围清凉，药物通过皮肤缓解眼部疲劳，使眼睛上下直肌部分得到放松，促进眼皮和眼球的血液良性循环，得以改善加速新陈代谢，缓解眼部肌肉紧张程度，使眼睛得到更多的营养，长期使用能够提升视力并保护眼睛的健康，最终达到改善近视的有益效果，本方剂为普通常见中医药，生产成本低、加工简单、使用简单、方便，适用范围广，便于储存和推广。
Description
技术领域
本发明涉及中药技术领域，尤其涉及一种用于治疗假性近视的复方谷精草液。
背景技术
2019年4月29日国家卫生健康委员会例行新闻发布会提到，2018年全国儿童青少年总体近视率为53.6％。其中，6岁儿童为14.5％，小学生为36.0％，初中生为71.6％，高中生为81.0％，学生视力不良问题突出，我国青少年的整体视力情况不容不乐观。
目前矫正的方法比较多见的主要有：配眼镜、手术治疗矫正等方法，配眼镜，一是不方便，二时依赖性强，手术治疗矫正，部分类型效果比较好，费用高，具有一定风险性，药物干预，多依赖于西药，并具有一定副作用，效果并不怎样明显。
在中国，中药在中国历史中经得起长期治疗实践的考验，其中有不少中草药对治疗近视有明显效果，特别是假性近视的治疗。根据《中医眼科学》近视常由青少年学习、工作时不善使用目力，劳瞻竭视，或禀赋不足，先天遗传所致。病机多系心阳衰弱，神光不得发越于远处；或为肝肾两虚，精血不足，以致神光衰微，光华不能远及。由此，需要研制一种没有副作用且有明显效果的治疗近视的新药。
发明内容
针对上述不足，本发明的目的是提供了一种复方谷精草液，选用谷精草、生地、蝉蜕、防风、决明子、枸杞、黄连、柏仁子、木贼、菊花、熟地为原料，经水煎法提取而成，对假性近视眼的治疗具有较好效果。
为实现上述目的，本发明所采用的技术方案是：
一种复方谷精草液，由下列重量(份)配比的原料制成：
谷精草50-70，生地18-30，蝉蜕8-12，防风8-12，决明子8-12，枸杞8-12，黄连10-20，柏仁子8-12，木贼8-12，菊花8-12，熟地18-30。
进一步地，所述最优重量(份)配比为谷精草60，生地24，蝉蜕10，防风10，决明子10，枸杞10，黄连15，柏仁子10，木贼10，菊花10，熟地24，上述的复方谷精草液的制作方法，包括以下步骤：
(1)、取谷精草，生地，蝉蜕，防风，决明子，枸杞，黄连，柏仁子，木贼，菊花，熟地加10倍量的水100℃提取2小时，滤出药液备用，得药渣；
(2)、取步骤(1)药渣，加6倍量的水100℃提取2小时，滤出药液备用；
(3)、合并步骤(1)、(2)药液，浓缩至温度80℃，相对密度1.1～1.3，冷却至常温，静置，取上清夜，加纯化水至规定量。
更进一步的，所述规定量药液为每100g谷精草可制备4～5L药液比。
本发明的有益效果为：本发明所提供的复方谷精草液，通过浸泡本发明的复方谷精草液的眼膜纸敷于眼睛周围，能使眼睛周围清凉，药物通过皮肤缓解眼部疲劳，使眼睛上下直肌部分得到放松，促进眼皮和眼球的血液良性循环，得以改善加速新陈代谢，缓解眼部肌肉紧张程度，使眼睛得到更多的营养，长期使用能够提升视力并保护眼睛的健康，最终达到改善近视的有益效果，本方剂为普通常见中医药，生产成本低、加工简单、使用简单、方便，适用范围广，便于储存和推广。
具体实施方式
为了使本发明的技术方案更加清楚明确，下面结合具体实施例作进一步阐述：
本发明一种复方谷精草液，由下列重量(份)配比的原料制成：谷精草50-70，生地18-30，蝉蜕8-12，防风8-12，决明子8-12，枸杞8-12，黄连10-20，柏仁子8-12，木贼8-12，菊花8-12，熟地18-30。
上述药方主要药材的药效概况如下：
谷精草具有轻浮升散，善疏散头面风热、明目退翳；生地具清热凉血，养阴生津，润肠；蝉蜕性味甘、寒，入肝、肺经，具有疏散风热、透疹止痒、退翳明目、熄风止痉的功效；防风有疏风、清热、解表、止泻、止血的功效；决明子具有清热明目，润肠通便功效，主治目赤肿痛，羞明多泪，目暗不明，头痛，眩晕；枸杞具有滋补肝肾，益精明目的功效；黄连具有清热燥湿，泻火解毒功效；柏仁子具有养心安神，润肠通便的功效；木贼具有疏散风热，明目退翳功效，主治风热目赤，迎风流泪，目生翳障，出血证；菊花具有疏散风热，平抑肝阳，清肝明目，清热解毒功效；熟地具有补血养阴，填经益髓的功效。各药配合，以谷精草之君归肝、肺经，黄连泻火、清热燥湿，生地凉血清热、生津止渴，熟地、柏子仁为臣养心，诸药共凑疏散风热，通调经络，养心安神，益目生精之功效。清热化瘀药液直接外敷于眼睛处，能提高组织细胞的渗透性，有利于药物吸收，增强眼部微循环体系改善其疗效。
实施例1
谷精草50g，生地18g，蝉蜕8g，防风8g，决明子8g，枸杞8g，黄连10g，柏仁子8g，木贼8g，菊花8g，熟地18g加水2.5L，100℃提取2小时，滤出药液A备用；
取药渣，加水2L，100℃提取2小时，滤出药液B备用；
合并药液A、B，浓缩至温度80℃，相对密度1.2，冷却至常温后，静置，取上清液，加纯化水，得复方谷精草液体4L；
取复方谷精草液，用浸泡本发明的眼膜纸以湿敷眼睛处，每天换药两次至视力恢复。
实施例2
取谷精草60，生地24，蝉蜕10，防风10，决明子10，枸杞10，黄连15，柏仁子10，木贼10，菊花10，熟地24加水3L；
制备方法同实施例1，得复方谷精草液，用以湿敷患处。
实施例3
取谷精草70，生地30，蝉蜕12，防风12，决明子12，枸杞12，黄连20，柏仁子12，木贼12，菊花12，熟地30；
制备方法同实施例1，得复方谷精草液，用以湿敷患处。
为了客观评价本发明临床效果，自2018年5月7日至2018年5月21日，对200名在校近视患者学生进行全程跟进采集数据，并进行了数据分析，分析结果如下：
200例中，小学生50名，其中男25例，女25例，年龄10-12岁，每天中午晚上各一次贴敷，每次20分钟，有效45例，无效5例，有效率90％；中学生100名，其中男50例，女50例，年龄13-17岁，每天中午晚上各一次贴敷，每次20分钟，效果是，有效95例，无效5例，有效率95％；上班族50名，其中男25例，女25例，年龄21-35岁，每天中午晚上各一次贴敷，每次20分钟，效果是，有效47例，无效3例，有效率94％。
更详细分析如下：
案例分析一：其中小学生50名中，视力0.5-0.8之间，0.5的人数为10人，0.6-0.8的人数为40人，
方法：每天中午午休、晚上睡前两次使用本发明中药眼贴湿敷疗法，每次20分钟以上，
结果：经过一个月的治疗，其中，视力0.5的学生提升到0.8的视力的有10人，视力0.8的近视学生视力提升至国家标准1.0以上的22人；提升至双眼1.2以上10人，提升至双眼1.5视力的有3人，有5人无效，有效率为90％。
案例分析二、其中中学生100名视力在0.4-0.5之间的有20人，0.6--0.8之间的80人，
方法：每天中午午休、晚上睡前两次使用本发明中药湿敷疗法，每次20分钟以上，
结果：经过一个月的治疗，其中，视力在0.4-0.5之间的学生20名中提升到0.6-0.8幅度有18人，提升到1.0的有2人，视力在0.6-0.8之间的学生80名中提升到1.0视力的有75人，无效5人，有效率为95％；
案例分析三、上班族50名中视力在0.5的10人，0.6--0.8的有40人，
方法：每天中午午休、晚上睡前两次使用本发明中药湿敷疗法，每次20分钟以上，
结果：经过一个月的治疗，其中，视力0.5的10人中，全部提升到0.8视力，原视力0.6-0.8的40人中提升到1.0的有31人，提升到1.0的有3人，有3人不同程度的提升，3人无效，有效率为94％；
从治疗结果可看出，总有效率为93％，对青少年近视的治疗具有良好效果。
上述实施方式仅为清楚说明本发明所作的举例，并非对本发明保护范围的限定，任何人在本发明的启示下都可得出其他不同形式的变化或变动，凡由此引申出的显而易见的变化或变动，均落在本发明的保护范围之内。
Claims (4)
1.一种复方谷精草液，其特征在于，所述复方谷精草液由下列重量(份)配比的原料制成：
谷精草50-70，生地18-30，蝉蜕8-12，防风8-12，决明子8-12，枸杞8-12，黄连10-20，柏仁子8-12，木贼8-12，菊花8-12，熟地18-30。
2.根据权利要求1所述的复方谷精草液，其特征在于：所述重量(份)配比为谷精草50，生地24，蝉蜕10，防风10，决明子10，枸杞10，黄连15，柏仁子10，木贼10，菊花10，熟地24。
3.根据权利要求1所述的复方谷精草液，其特征在于：所述复方谷精草液的制备包括如下步骤：
(1)、取谷精草60，生地24，蝉蜕10，防风10，决明子10，枸杞10，黄连15，柏仁子10，木贼10，菊花10，熟地24。加10倍量的水100℃提取2小时，滤出药液备用，得药渣；
(2)、取步骤(1)药渣，加6倍量的水100℃提取2小时，滤出药液备用；
(3)、合并步骤(1)、(2)药液，浓缩至温度80℃，相对密度1.1～1.3，冷却至常温，静置，取上清液，加纯化水至规定量。
4.根据权利要求3所述的复方谷精草液，其特征在于，所述规定量药液为每100g谷精草可制备4-5L药液比。
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