CN112888447A - 减少菌群失调和恢复微生物群系的方法 - Google Patents
减少菌群失调和恢复微生物群系的方法 Download PDFInfo
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- CN112888447A CN112888447A CN201980068341.3A CN201980068341A CN112888447A CN 112888447 A CN112888447 A CN 112888447A CN 201980068341 A CN201980068341 A CN 201980068341A CN 112888447 A CN112888447 A CN 112888447A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2561/00—Nucleic acid detection characterised by assay method
- C12Q2561/113—Real time assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/10—Detection mode being characterised by the assay principle
- C12Q2565/101—Interaction between at least two labels
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862765165P | 2018-08-17 | 2018-08-17 | |
| US62/765,165 | 2018-08-17 | ||
| US201862724185P | 2018-08-29 | 2018-08-29 | |
| US62/724,185 | 2018-08-29 | ||
| US201962815395P | 2019-03-08 | 2019-03-08 | |
| US62/815,395 | 2019-03-08 | ||
| US201962829513P | 2019-04-04 | 2019-04-04 | |
| US62/829,513 | 2019-04-04 | ||
| US201962829959P | 2019-04-05 | 2019-04-05 | |
| US62/829,959 | 2019-04-05 | ||
| PCT/US2019/046926 WO2020037271A1 (en) | 2018-08-17 | 2019-08-16 | Methods of decreasing dysbiosis and restoring a microbiome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112888447A true CN112888447A (zh) | 2021-06-01 |
Family
ID=69525842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980068341.3A Pending CN112888447A (zh) | 2018-08-17 | 2019-08-16 | 减少菌群失调和恢复微生物群系的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12161680B2 (https=) |
| EP (1) | EP3836946B1 (https=) |
| JP (2) | JP7558170B2 (https=) |
| KR (1) | KR20210091119A (https=) |
| CN (1) | CN112888447A (https=) |
| AU (1) | AU2019321681A1 (https=) |
| IL (2) | IL280779B2 (https=) |
| WO (1) | WO2020037271A1 (https=) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113486954A (zh) * | 2021-07-06 | 2021-10-08 | 广西爱生生命科技有限公司 | 一种肠道微生态差异菌分类处理方法及肠道健康评估方法 |
| CN114496279A (zh) * | 2022-01-12 | 2022-05-13 | 广州保量医疗科技有限公司 | 菌群移植配型的排序方法、系统、计算机设备及存储介质 |
| CN119970806A (zh) * | 2025-02-25 | 2025-05-13 | 浙江大学 | 多毛假解黄酮菌在制备预防、治疗和/或改善溃疡性结肠炎的药物中的应用 |
| CN120779034A (zh) * | 2025-07-15 | 2025-10-14 | 中山大学附属口腔医院 | 一种牙周炎相关标志物及应用 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
| ES2993669T3 (en) | 2011-12-01 | 2025-01-03 | Univ Tokyo | Human-derived bacteria that induce proliferation or accumulation of regulatory t cells |
| CA3226196A1 (en) | 2016-06-14 | 2017-12-21 | Vedanta Biosciences, Inc. | Treatment of clostridium difficile infection |
| AU2019321681A1 (en) * | 2018-08-17 | 2021-02-25 | Vedanta Biosciences, Inc. | Methods of decreasing dysbiosis and restoring a microbiome |
| KR102503766B1 (ko) * | 2020-06-16 | 2023-02-23 | 씨제이바이오사이언스 주식회사 | 장내 마이크로바이옴 지수를 결정하기 위한 장치, 방법 및 명령을 기록한 기록 매체 |
| CN111796043B (zh) * | 2020-08-15 | 2022-02-22 | 山东北大高科华泰制药有限公司 | 注射用盐酸罂粟碱粉针剂及其质量检测方法 |
| WO2022159711A1 (en) | 2021-01-21 | 2022-07-28 | Vedanta Biosciences, Inc. | Compositions and methods for treating hepatic encephalopathy |
| EP4362961A1 (en) * | 2021-06-28 | 2024-05-08 | Vedanta Biosciences, Inc. | Methods of colonizing a microbiome, treating and/or preventing inflammatory bowel disease and graft versus host disease |
| JP2024540203A (ja) * | 2021-11-08 | 2024-10-31 | アルティメット メディシン アーゲー | ミクログリア機能障害を治療し、代謝機能障害を改善するための方法および組成物 |
| EP4698197A1 (en) * | 2023-04-20 | 2026-02-25 | Ecole Polytechnique Federale De Lausanne (Epfl) | AN ANTIBIOTIC AND A MICROORGANISM HAVING BILE ACID 7a-DEHYDROXYLATION ACTIVITY FOR TREATING NON-INFECTIOUS DISEASES |
| EP4704871A2 (en) * | 2023-04-28 | 2026-03-11 | Vedanta Biosciences, Inc. | Compositions and methods for treating clostridioides difficile infection |
| WO2025076184A1 (en) | 2023-10-03 | 2025-04-10 | Vedanta Biosciences, Inc. | Methods of decreasing dysbiosis and restoring a microbiome |
| WO2025093778A1 (en) * | 2023-11-05 | 2025-05-08 | Human Biome Institute S.A. | Functional compositions and methods of use thereof in eradication and/or decolonization of antibiotic-resistant bacteria and restoration of healthy microbiota |
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| WO2011033310A1 (en) * | 2009-09-17 | 2011-03-24 | William John Martin | Encapsulated intestinal flora extracted from feces for use in the treatment of gastrointestinal disorders |
| WO2017218680A1 (en) * | 2016-06-14 | 2017-12-21 | Vedanta Biosciences, Inc. | Treatment of clostridium difficile infection |
| WO2018080477A1 (en) * | 2016-10-26 | 2018-05-03 | The Joan & Irwin Jacobs Technion-Cornell Institute | Systems and methods for ultra-fast identification and abundance estimates of microorganisms using a kmer-depth based approach and privacy-preserving protocols |
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| US20180169153A1 (en) * | 2014-11-25 | 2018-06-21 | Evelo Biosciences, Inc. | Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft verses host disease |
| US20180221286A1 (en) * | 2013-03-14 | 2018-08-09 | Therabiome, Llc | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
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-
2019
- 2019-08-16 AU AU2019321681A patent/AU2019321681A1/en active Pending
- 2019-08-16 JP JP2021532282A patent/JP7558170B2/ja active Active
- 2019-08-16 US US17/268,781 patent/US12161680B2/en active Active
- 2019-08-16 KR KR1020217007593A patent/KR20210091119A/ko not_active Ceased
- 2019-08-16 IL IL280779A patent/IL280779B2/en unknown
- 2019-08-16 CN CN201980068341.3A patent/CN112888447A/zh active Pending
- 2019-08-16 WO PCT/US2019/046926 patent/WO2020037271A1/en not_active Ceased
- 2019-08-16 IL IL317775A patent/IL317775A/en unknown
- 2019-08-16 EP EP19849346.2A patent/EP3836946B1/en active Active
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2024
- 2024-05-23 JP JP2024083941A patent/JP7851353B2/ja active Active
- 2024-10-31 US US18/932,688 patent/US20250161375A1/en active Pending
Patent Citations (7)
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| US20090269321A1 (en) * | 2005-03-03 | 2009-10-29 | Toshihiro Sashihara | Immune Function Modulating Agents |
| WO2011033310A1 (en) * | 2009-09-17 | 2011-03-24 | William John Martin | Encapsulated intestinal flora extracted from feces for use in the treatment of gastrointestinal disorders |
| US20180221286A1 (en) * | 2013-03-14 | 2018-08-09 | Therabiome, Llc | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
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| CN113486954A (zh) * | 2021-07-06 | 2021-10-08 | 广西爱生生命科技有限公司 | 一种肠道微生态差异菌分类处理方法及肠道健康评估方法 |
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| CN119970806A (zh) * | 2025-02-25 | 2025-05-13 | 浙江大学 | 多毛假解黄酮菌在制备预防、治疗和/或改善溃疡性结肠炎的药物中的应用 |
| CN120779034A (zh) * | 2025-07-15 | 2025-10-14 | 中山大学附属口腔医院 | 一种牙周炎相关标志物及应用 |
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| US20220143108A1 (en) | 2022-05-12 |
| KR20210091119A (ko) | 2021-07-21 |
| WO2020037271A1 (en) | 2020-02-20 |
| IL280779A (en) | 2021-04-29 |
| JP2022500489A (ja) | 2022-01-04 |
| JP7851353B2 (ja) | 2026-04-24 |
| US20250161375A1 (en) | 2025-05-22 |
| JP2024119856A (ja) | 2024-09-03 |
| IL317775A (en) | 2025-02-01 |
| EP3836946B1 (en) | 2026-04-22 |
| US12161680B2 (en) | 2024-12-10 |
| IL280779B1 (en) | 2025-01-01 |
| AU2019321681A1 (en) | 2021-02-25 |
| EP3836946A1 (en) | 2021-06-23 |
| IL280779B2 (en) | 2025-05-01 |
| EP3836946A4 (en) | 2022-05-04 |
| JP7558170B2 (ja) | 2024-09-30 |
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