CN112869731B - Production calibration method of pulmonary function instrument gas volume calibration device - Google Patents
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Abstract
The invention relates to the field of medicine and sports medicine, in particular to a production and calibration method of a gas volume calibration device of a pulmonary function instrument. Since the gas volumes are different under different temperature, humidity and atmospheric pressure environments, the testing device for the cardiopulmonary exercise function test must be calibrated using the gas volume calibration device of the pulmonary function machine before the test to verify that the test data under the controlled environment is accurate. At present, the production process and the calibration method of the gas volume calibration device of the lung function instrument are not reported and implemented in China.
Description
The application has the application number as follows: 2018102808641 with the name: the divisional application of the invention patent application of 'a production calibration method of a lung function instrument gas volume calibration device' is as follows: 04/h 02/2018.
Technical Field
The invention relates to the field of medicine and sports medicine, in particular to a production and calibration method of a lung function instrument gas volume calibration device.
Background
The heart and lung movement function test is divided into a static lung function test and a movement heart and lung function test, and is a forward-edge technology which is used for providing a quantitative result by collecting the flow rate and the gas components of gas exhaled by a human body in a resting state and a movement state and combining other physiological indexes such as electrocardio, blood pressure, oxyhemoglobin saturation and the like and evaluating the condition and the movement capacity of a respiratory system of the human body.
The gas flow rate is a key parameter, and the volume can be obtained by converting the gas flow rate with time, and is used for describing many respiratory tract related parameters such as VC (vital capacity), VT (tidal volume), IC (deep inhalation volume), TLC (total lung volume) and the like, thereby providing a basis for clinical diagnosis.
Since the gas volumes are different under different temperature, humidity and atmospheric pressure environments, the testing device for the cardiopulmonary exercise function test must be calibrated using the gas volume calibration device of the pulmonary function machine before the test to verify that the test data under the controlled environment is accurate.
The principle of the gas volume calibration device of the pulmonary function instrument, also called a calibration cylinder, is to pull or push the pulmonary function instrument volume calibration device (at a given known volume, for example, 3L), perform air exhaust and air suction, and then determine the accuracy of the flow meter in the pulmonary function instrument device through integral conversion of time (no matter the speed is fast or slow, the speed is fast, the time is short, and the speed is slow, the time is relatively long), and the flow meter can also give a conclusion that the volume is within a standard error range (for example, 3L).
The whole body of the gas volume calibration device of the pulmonary function instrument is cylindrical, the calibration device is pushed and pulled through a piston pull rod, the piston separates the whole cavity into two spaces, one end of the calibration device is provided with an air hole for air inlet when the pull rod is pulled out and air exhaust when the pull rod is pushed out, and the calibration device is a main passage of gas during calibration; the other end is provided with a plurality of exhaust holes for ensuring the dynamic balance of air pressure in the cavity and ensuring the free push and pull. Internationally, the precision range of the gas volume calibration device of the lung function instrument is +/-15 ml, and the production process and the calibration method for verifying and calibrating the gas volume calibration device of the lung function instrument are not reported and implemented at home at present.
Disclosure of Invention
In order to solve the above problems, the present invention provides a method for producing and calibrating a gas volume calibration device of a pulmonary function instrument, which is used for realizing high precision and low error of the gas volume calibration device during production, assembly and calibration.
The technical scheme for solving the technical problem is a production and calibration method of a lung function instrument gas volume calibration device, which comprises the following steps:
the method comprises the following steps: controlling the temperature and humidity in the laboratory through temperature control equipment, and recording after keeping constant in a time period T;
step two: the electronic balance with the measurement precision of more than 0.1g and the measurement range of more than 5kg is calibrated and recorded on a verified marble platform by using a traceable mass block, and the electronic balance is kept horizontal before operation;
step three: installing a pull rod handle in the gas volume calibration device of the pulmonary function instrument at one end of a pull rod, installing a piston at the other end of the pull rod handle, plugging the piston into the main cavity, installing a rear cover on the main cavity, and pulling the pull rod handle until the tail end of the main cavity abuts against the rear cover;
step four: fixing the gas volume calibration device of the lung function instrument on the first tool, and enabling the pull rod handle and the outer edge of the main cavity body to be completely attached to the inner surface of the first tool.
Step five: placing the mounted lung function instrument gas volume calibration devices and the tools on an electronic balance on a marble platform one by one for weighing and peeling;
step six: injecting distilled water into the main cavity until the indication value of the electronic balance reaches a target value, and recording;
step seven: after weighing is finished, a front cover of the gas volume calibration device of the pulmonary function instrument is arranged on the main cavity, and moisture detection test paper is attached to the joint of the front cover and the main cavity;
step eight: fixing the first tool and the gas volume calibration device of the pulmonary function instrument on a second tool, and standing for more than 1 minute;
step nine: a motor on the tool II is electrified, so that the pull rod handle drives the piston to push the main cavity body at a constant speed until the moisture detection test paper is discolored, and the motor is powered off and records;
step ten: after calculation and verification, the gas volume calibration device of the pulmonary function instrument is taken down from the first tool, and a positioning and locking device is installed at the joint rear cover of the pull rod handle.
Preferably, gaseous volume calibrating device of pulmonary function appearance includes pull rod handle, location locking device, back lid, pull rod, piston, the main cavity body and protecgulum, the pull rod handle is installed on the piston, the piston is established in the main cavity body, the back lid is installed to the rear end of the main cavity body, the protecgulum is installed to the front end of the main cavity body, be equipped with back lid through-hole on the back lid, be equipped with the protecgulum through-hole on the protecgulum, be equipped with location locking device on the pull rod.
Preferably, the fixture comprises a base and a main cavity fixing plate, the main cavity fixing plate is installed on the base and further comprises angle steel reinforcing ribs, and the angle steel reinforcing ribs are connected with the main cavity fixing plate and the base respectively.
Preferably, the second tool comprises an operating platform, a motor, an ejector rod, a fixing frame and a pressing rod, wherein the fixing frame is installed on the operating platform, the pressing rod is arranged on the fixing frame, the ejector rod is linked with the motor, and the ejector rod penetrates through the operating platform and is located below the pressing rod.
The production and calibration method of the lung function instrument gas volume calibration device has the following advantages: the device for calibrating the gas volume of the lung function instrument is made into a home-made product, fills the blank of a domestic calibration method, and achieves the aim of domestic calibration; by adopting the production process and the calibration method, theoretically, the precision of the gas volume calibration device of the pulmonary function instrument can be ensured to be at least within +/-1.5 ml, which is far higher than the precision of foreign like products; distilled water (namely pure water) is used as a reference substance, so that the calibration precision is improved, and accumulated errors are avoided; by adopting the production process and the calibration method, partial system errors are eliminated by a smart structure at the beginning of design; only the operating environment needs to be controlled, and the operation is simple and easy to realize; the requirement on the professional level of operators is low; the test cost is low.
Drawings
Fig. 1 is a schematic structural diagram of a lung function instrument gas volume calibration device of the present invention.
Fig. 2 is an assembly schematic of the main chamber of the pulmonary function device gas volume calibration device of the present invention.
Fig. 3 is a schematic structural diagram of a pull rod of the gas volume calibration device of the pulmonary function instrument.
Fig. 4 is a schematic structural diagram of a front cover of the gas volume calibration device of the pulmonary function instrument.
Fig. 5 is a schematic structural diagram of a rear cover of the gas volume calibration device of the pulmonary function instrument.
Fig. 6 is a schematic structural diagram of a first tool of the present invention.
Fig. 7 is an assembly schematic diagram of the lung function instrument gas volume calibration device and the first tool of the present invention.
Fig. 8 is a schematic structural diagram of a second tool of the present invention.
Fig. 9 is an assembly schematic diagram of a first tool and a second tool of the present invention.
Description of the drawings: 1. the pull rod handle, 2, the location locking device, 3, the back lid, 31, back lid through-hole, 4, the pull rod, 5, the piston, 6, the main cavity body, 7, the protecgulum, 71, protecgulum through-hole, 8, the base, 9, main cavity body fixed plate, 10, angle steel strengthening rib, 11, operation panel, 12, the motor, 13, the ejector pin, 14, the mount, 15, the depression bar.
Detailed Description
As shown in the figure, a method for producing and calibrating a pneumonometer gas volume calibration device comprises the following steps:
the method comprises the following steps: controlling the temperature and humidity in the laboratory through temperature control equipment, and recording after keeping constant in a time period T;
step two: the electronic balance with the measurement precision of more than 0.1g and the measurement range of more than 5kg is calibrated and recorded on a verified marble platform by using a traceable mass block, and the electronic balance is kept horizontal before operation;
step three: a pull rod handle (1) in the gas volume calibration device of the lung function instrument is arranged at one end of a pull rod, a piston (5) is arranged at the other end of the pull rod handle (1), the piston (5) is plugged into a main cavity, a rear cover (3) is arranged on the main cavity (6), and then the pull rod handle (1) is pulled to the tail end of the main cavity (6) to be abutted against the rear cover (3);
step four: fixing the gas volume calibration device of the lung function instrument on a first tool, and completely attaching the pull rod handle (1) and the outer edge of the main cavity (6) to the inner surface of the tool.
Step five: placing the mounted lung function instrument gas volume calibration devices and the tools on an electronic balance on a marble platform one by one, weighing and peeling;
step six: injecting distilled water into the main cavity until the indication value of the electronic balance reaches a target value, and recording;
step seven: after weighing is finished, a front cover (7) of the gas volume calibration device of the pulmonary function instrument is arranged on the main cavity body (6), and moisture detection test paper is attached to the joint of the front cover (7) and the main cavity body (6);
step eight: fixing the tool I and the lung function instrument gas volume calibration device on a tool II, and standing for more than 1 minute;
step nine: a motor on the second tool is electrified, so that the pull rod handle (1) drives the piston (5) to be pushed into the main cavity (6) at a constant speed until the moisture detection test paper is discolored, and the motor is powered off and records;
step ten: after calculation and verification, the gas volume calibration device of the lung function instrument is taken down from the first tool, and a positioning and locking device (2) is arranged at the joint rear cover (3) of the pull rod handle (1).
Gaseous volume calibrating device of pulmonary function appearance includes pull rod handle 1, location locking device 2, hou gai 3, pull rod 4, piston 5, the main cavity body 6 and protecgulum 7, pull rod handle 1 is installed on piston 5, piston 5 is established at the internal 6 of main cavity, back lid 3 is installed to the rear end of the main cavity body 6, protecgulum 7 is installed to the front end of the main cavity body 6, be equipped with hou gai through-hole 31 on the back lid 3, be equipped with protecgulum through-hole 71 on the protecgulum 7, be equipped with location locking device 2 on the pull rod 4.
The first tool comprises a base 8 and a main cavity body fixing plate 9, the main cavity body fixing plate 9 is installed on the base 8, and further comprises angle steel reinforcing ribs 10, and the angle steel reinforcing ribs 10 are respectively connected with the main cavity body fixing plate 9 and the base 8.
The second tool comprises an operating platform 11, a motor 12, an ejector rod 13, a fixing frame 14 and a pressing rod 15, wherein the fixing frame 14 is installed on the operating platform 11, the pressing rod 15 is arranged on the fixing frame 14, the ejector rod 13 is linked with the motor 12, and the ejector rod 13 penetrates through the operating platform 11 and is located below the pressing rod 15.
In practice, the production and calibration error is set to δ, which includes both the systematic error f (x) and the random error f (y), i.e., δ = f (x) + f (y)
The system error is set as f (x), and the inherent error C of the electronic balance (in a verification period, C is a constant), the water shake in the propulsion process, the flatness of the marble platform and the inclination angle of the tool 1 are mainly considered. The water shaking in the propulsion process can be controlled to be the lowest (and the water surface is concave when in the cavity) through the slow motor and the speed change gear, so that the water shaking can be ignored; the flatness of the marble platform and the tilt angle of the fixture 1, as long as its tilt direction (after measurement) is known, placing the moisture indicator paper at the higher end relative to the horizontal angle ignores its error because the water surface (the combined effect of tilt angle and surface tension) will contact the moisture indicator paper at the last time after filling up other areas. Thus f (x) = C
The random error is f (y), and the delay time is mainly considered, and the volume of the discharged distilled water is set as V1. V1 is composed of a delay time t1 of human body reaction, a test paper reaction delay time t2, a tie rod advancing speed V and a cross-sectional area S of the front cover through hole, and has a specific formula of V1= S × V × (t 1+ t 2). Thus f (y) = V1.
Therefore, the production and calibration error δ = f (x) + f (y) = C/ρ + V1 (ρ is the density of distilled water under a specific atmospheric pressure, temperature and humidity environment).
Theoretically, the inherent error C of the electronic balance is less than or equal to 0.1g (the measurement error of the current technology level reaching 0.1g is easy to realize, and the electronic balance with the measurement error of 1g is feasible in practical application relative to the error range given abroad); the density rho of the distilled water is in the environment of 0-100 ℃ (the laboratory temperature is controlled to be about 20 ℃ under the general condition), and the density (unit: kg/m < 3 >) is in the interval [958.345, 999.972 ]; the interval of C/rho (unit: ml) is within 0.10003,0.104347, and the maximum value is taken, wherein C/rho is less than or equal to 0.104347ml; the delay time t1 of the human body reaction is generally 0.2-0.4 s, and t1 is rounded upwards to be less than or equal to 1s; the reaction delay time t2 of the test paper is less than or equal to 1s (normal condition); the cross-sectional area S of the through hole of the front cover is less than or equal to 12.56637cm2 (the diameter R of the through hole of the front cover is less than 2cm if necessary); when the rod travel speed v is sufficiently small, speeds of typically up to 0.05cm/s are feasible, even lower speeds; the volume of multiple discharges V1= S x V x (t 1+ t 2) is less than or equal to 1.256637ml;
so the production and calibration error is delta = f (x) + f (y) = C/rho + V1=1.360984ml, rounding up delta ≦ 1.5ml.
Meanwhile, if each part meets the following technical requirements, the precision is better:
a main cavity: the inner wall is smooth, parallel and cylindrical; a material having a high surface hardness; external threads are adopted at the two ends; a front cover: a through hole which adopts internal threads and can be connected with the main cavity body; a material having a high surface hardness; a rear cover: the through holes (a plurality of through holes) are provided, and can be connected with the main cavity by adopting internal threads; a material having a high surface hardness; wherein, the outer surface of the through hole of the pull rod is made of high-hardness material, and the interior of the through hole is made of wear-resistant material (the purposes of preventing collision damage and errors caused by deformation, being easy to push and pull and having no noise); a pull rod handle: the operation is facilitated, and no special requirement exists; positioning and locking devices: high-hardness materials are adopted (the purposes are preventing collision damage and preventing errors caused by deformation); a pull rod: no special requirement is required; considering a polymer synthetic material; a piston: the main body is made of high-hardness materials, and a rubber ring is additionally arranged to play a role in reducing friction, noise and sealing; tooling: scheme 1, two vertical baffles are provided with measured scales, and are positioned vertically by adopting an isosceles right triangle method; the two upright baffles can move left and right and are used for adjusting, installing and fixing equipment; the outer surface and the inner surface of the bottom end are flat (verification is needed); the bottom area is sufficiently large.
While the preferred embodiments of the present invention have been described above, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention, and the technical scope of the invention is not limited to the embodiments described in the specification and must be determined by the claims.
Claims (1)
1. A method of producing and calibrating a pulmonary function device gas volume calibration device, comprising:
controlling the temperature and humidity in a laboratory through temperature control equipment, and recording after the temperature and the humidity are kept constant in a time period T;
secondly, calibrating and recording an electronic balance with the measurement precision of more than 0.1g and the measurement range of more than 5kg on a calibrated marble platform by using a traceable mass block, and keeping the electronic balance horizontal before operation;
step three, a pull rod handle in the gas volume calibration device of the lung function instrument is arranged at one end of a pull rod, a piston is arranged at the other end of the pull rod handle, the piston is plugged into the main cavity, a rear cover is arranged on the main cavity, and then the pull rod handle is pulled to the tail end of the main cavity to be abutted against the rear cover;
fixing the gas volume calibration device of the lung function instrument on the first tool, and completely attaching the pull rod handle, the outer edge of the main cavity and the inner surface of the tool; the tool comprises a base (8), a main cavity fixing plate (9), an angle steel reinforcing rib (10), and a tool body I, wherein the main cavity fixing plate (9) is installed on the base (8), and the angle steel reinforcing rib (10) is respectively connected with the main cavity fixing plate (9) and the base (8);
placing the mounted lung function instrument gas volume calibration devices and the tools on an electronic balance on a marble platform, weighing and peeling;
step six, injecting distilled water into the main cavity until the indication value of the electronic balance reaches a target value, and recording;
step seven, after weighing is finished, installing a front cover of the gas volume calibration device of the pulmonary function instrument on the main cavity body, and attaching moisture detection test paper at the joint of the front cover and the main cavity body;
fixing the tool I and the gas volume calibration device of the pulmonary function instrument on the tool II, and standing for more than 1 minute; the two-stage tool comprises an operating table (11), a motor (12), a push rod (13), a fixing frame (14) and a pressure rod (15), wherein the fixing frame (14) is installed on the operating table (11), the pressure rod (15) is arranged on the fixing frame (14), the push rod (13) is linked with the motor (12), and the push rod (13) penetrates through the operating table (11) and is located below the pressure rod (15);
step nine, electrifying a motor on the tool II, driving a piston to be pushed into the main cavity at a constant speed by a pull rod handle until the moisture detection test paper is discolored, powering off the motor, and recording;
step ten, after calculation and verification, taking the gas volume calibration device of the pulmonary function instrument down from the first tool, and installing a positioning and locking device at the joint rear cover of the pull rod handle;
the gas volume calibration device of the pulmonary function instrument comprises a pull rod handle (1), a positioning and locking device (2), a rear cover (3), a pull rod (4), a piston (5), a main cavity body (6) and a front cover (7), wherein the pull rod handle (1) is installed on the piston (5), the piston (5) is arranged in the main cavity body (6), the rear cover (3) is installed at the rear end of the main cavity body (6), the front cover (7) is installed at the front end of the main cavity body (6), a rear cover through hole (31) is formed in the rear cover (3), a front cover through hole (71) is formed in the front cover (7), and the positioning and locking device (2) is arranged on the pull rod (4);
the main cavity (6) is in a cylindrical shape with smooth and parallel inner walls; external threads are adopted at the two ends;
the front cover (7) is provided with a through hole which adopts internal threads and can be connected with the main cavity body;
the rear cover (3) is provided with a plurality of through holes which adopt internal threads and can be connected with the main cavity body;
the positioning locking device (2) is made of high-hardness materials so as to prevent collision damage and errors caused by deformation;
the piston (5) is additionally provided with a rubber ring to play the roles of reducing friction, noise and sealing.
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| CN202110035565.3A CN112869731B (en) | 2018-04-02 | 2018-04-02 | Production calibration method of pulmonary function instrument gas volume calibration device |
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| CN201810280864.1A CN108714030B (en) | 2018-04-02 | 2018-04-02 | Production calibration method of pulmonary function instrument gas volume calibration device |
| CN202110035565.3A CN112869731B (en) | 2018-04-02 | 2018-04-02 | Production calibration method of pulmonary function instrument gas volume calibration device |
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| US6096558A (en) * | 1997-09-13 | 2000-08-01 | Drager Sicherheitstechnik Gmbh | Process for calibrating a breath alcohol-measuring instrument |
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| CN107041752A (en) * | 2017-04-18 | 2017-08-15 | 南阳师范学院 | A kind of Weighing type spirometric device |
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| US5313955A (en) * | 1992-10-30 | 1994-05-24 | Rodder Jerome A | Pulmonary flow head |
| JP2010048617A (en) * | 2008-08-20 | 2010-03-04 | Ricoh Elemex Corp | Gas meter |
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- 2018-04-02 CN CN202110035565.3A patent/CN112869731B/en active Active
- 2018-04-02 CN CN201810280864.1A patent/CN108714030B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096558A (en) * | 1997-09-13 | 2000-08-01 | Drager Sicherheitstechnik Gmbh | Process for calibrating a breath alcohol-measuring instrument |
| CN1540298A (en) * | 2003-04-21 | 2004-10-27 | 上海威尔泰工业自动化股份有限公司 | Method for calibrating dynamic volumel |
| CN201223392Y (en) * | 2008-06-12 | 2009-04-22 | 中国测试技术研究院电离辐射研究所 | Equipment for calibrating lung function instrument |
| CN202128464U (en) * | 2011-07-20 | 2012-02-01 | 魏川 | Device for pushing out gas in the event of standardizing and calibrating spirometer |
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| CN108714030A (en) | 2018-10-30 |
| CN112869731A (en) | 2021-06-01 |
| CN108714030B (en) | 2021-04-16 |
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