CN112842961A - Exfoliating preparation prepared based on peony extract - Google Patents

Exfoliating preparation prepared based on peony extract Download PDF

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Publication number
CN112842961A
CN112842961A CN202110208710.3A CN202110208710A CN112842961A CN 112842961 A CN112842961 A CN 112842961A CN 202110208710 A CN202110208710 A CN 202110208710A CN 112842961 A CN112842961 A CN 112842961A
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Prior art keywords
parts
aqueous extract
weight
extract
peony
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Pending
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CN202110208710.3A
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Chinese (zh)
Inventor
李晓君
渠志灿
丁东源
梁锐
李建丽
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Shanxi Na'an Biotechnology Co ltd
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Shanxi Na'an Biotechnology Co ltd
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Priority to CN202110208710.3A priority Critical patent/CN112842961A/en
Publication of CN112842961A publication Critical patent/CN112842961A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an exfoliating preparation prepared based on a peony extract, and particularly relates to the field of daily chemical cleaning, wherein the exfoliating preparation comprises, by weight, 20-40 parts of a peony active extract, 15-30 parts of an Entada phaseoloides aqueous extract, 10-20 parts of a viola clavata aqueous extract and 10-15 parts of a vetch aqueous extract. The invention has the advantages of less loss of active substances and less solvent residue.

Description

Exfoliating preparation prepared based on peony extract
Technical Field
The invention relates to the field of daily chemical cleaning, in particular to an exfoliating preparation prepared based on a peony extract.
Background
Peony is a perennial deciduous shrub belonging to the genus Paeoniaceae, the class Dicotyledoneae. Peony has the effects of nourishing blood and liver, lowering blood pressure and relieving pain. The peony can be used for treating symptoms of irregular menstruation, menstrual abdominal pain, amenorrhea, facial chloasma, skin aging and the like of a human body. Although the traditional peony has extremely wide application in the field of medical care, the traditional peony has very little application in the field of daily chemical cleaning.
Moreover, some daily chemical cleaners containing peony extracts on the market have the problems of high active substance loss, poor extract solubility, solvent residue and the like, and after the daily chemical cleaners are used by users, the daily chemical cleaners cannot remove skin cutin and the cleaners remain on the surface layer of the skin to cause skin problems such as acne, acne or dark red and the like.
Disclosure of Invention
The invention provides an exfoliating preparation prepared based on a peony extract, and the exfoliating preparation has the advantages of less loss of active substances and less solvent residue.
In order to achieve the purpose, the invention provides the following technical scheme:
the cutin removing preparation prepared based on the peony extract comprises, by weight, 20-40 parts of a peony active extract, 15-30 parts of an entada phaseoloides aqueous extract, 10-20 parts of a viola drumstick aqueous extract and 10-15 parts of a vetch aqueous extract.
Preferably, the exfoliating preparation further comprises at least one of an aqueous extract of rubus biflorus, an aqueous extract of pachyrhizus, an aqueous extract of leopard and an aqueous extract of gleditsia sinensis.
Preferably, the cutin removing preparation comprises, by weight, 20-40 parts of peony active extract, 15-30 parts of entada phaseoloides aqueous extract, 10-20 parts of viola drumstick aqueous extract, 10-15 parts of wild pea aqueous extract, 6-12 parts of rubus corchorifolius aqueous extract, 5-10 parts of cephalous aqueous extract, 1-5 parts of leopard aqueous extract and 1-3 parts of gleditsia sinensis aqueous extract.
Preferably, the exfoliating preparation comprises, by weight, 30 parts of a peony active extract, 25 parts of an entada phaseoloides aqueous extract, 15 parts of a viola drumstick aqueous extract, 13 parts of a vetch aqueous extract, 8 parts of a rubus corchorifolius aqueous extract, 8 parts of a cephalo aqueous extract, 3 parts of a leopard aqueous extract and 2 parts of a gleditsia sinensis aqueous extract.
Preferably, the preparation method of the peony active extract comprises the following steps:
s01, selecting the whole peony seedling of 2-3 years old, cleaning, drying, removing the main stem, and reserving peony leaves, peony roots and peony lateral branches, which are used as raw materials.
S02, crushing the raw materials to 20-40 meshes to obtain raw material powder.
S03, placing the obtained raw material powder and the obtained extracting solution in an extracting container according to the material-liquid ratio of 1:8-1:15, and carrying out high-speed shearing on the raw materials for 3-5min by adopting a high-speed shearing machine to obtain a material mixture.
S04, performing solid-liquid separation on the material mixture by vacuum filtration equipment to obtain filtrate and residue.
S05, placing the filtrate in a stainless steel container, freezing for 10-15 h at the temperature of-8 to-12 ℃, thawing at room temperature after freezing, performing vacuum filtration by adopting medium-speed qualitative filter paper, and removing precipitates to obtain a filtrate.
And S06, concentrating the obtained suction filtration liquid by adopting membrane concentration equipment to obtain 1/3-1/4 of the original volume, further obtaining concentrated liquid, and freeze-drying the concentrated liquid at low temperature to obtain a finished product.
The traditional preparation method of the peony extract comprises the following steps: the problems of more active substance loss, poor extract solubility, solvent residue and the like exist in hot water extraction, solvent extraction and the like, and the application in the field of cleaning daily chemicals is inconvenient. The method provided by the scheme has the following advantages:
1) said method comprises extracting at room temperature or a temperature below room temperature;
2) the above method does not employ organic solvent for extraction;
3) the method adopts freeze thawing method to remove the components unfavorable for dissolution.
4) The obtained product has high retention of active ingredients and no solvent residue, greatly improves the solubility, and can increase the use amount and make the efficacy of the product more easily exerted when applied to the field of cleaning daily chemicals.
5) The method adopts unstable acidic oxidation potential water as an extraction solvent, combines a high-speed shearing rapid extraction method, keeps the pH (2-3) of the extracting solution at a low value in a short time, and simultaneously recovers the pH of the extracting solution to be neutral in a subsequent longer working section, thereby avoiding the damage to membrane concentration equipment during the subsequent membrane concentration.
Of course, the pH can be adjusted by other inorganic acids, and after extraction, the pH can be adjusted to neutral by alkali liquor, but corresponding inorganic salts are formed, and if the product contains high inorganic salts, the product has a large influence on the stability of daily chemical products when added as daily chemical products. The process can avoid the phenomenon.
The characteristics of the peony active extract are as follows:
1) the total phenol content is 250-320mg/g
2) The content of total flavone is 65-90mg/g
3) The reduction amount of iron ions is 25-35 mu mol.
Has no solvent residue and good solubility, and is suitable for application in the field of daily chemicals, especially for products with lower pH (4-5.5), such as exfoliating cream, etc.
Preferably, in step S02, the ratio of the feed to the liquid is 1: 12.
Preferably, in step S04, the temperature condition is-10 ℃.
Preferably, in step S04, the frozen food is frozen for 12 hours.
Preferably, in step S05, the concentrated volume is 1/3 of the original volume.
The invention has the beneficial effects that:
in the invention, the cutin removing preparation is prepared by adding the peony active extract, the Entada phaseoloides aqueous extract, the viola coptidis aqueous extract and the vetch aqueous extract into the components, so that cutin on the skin of a user can be removed, and the viola coptidis aqueous extract and the vetch aqueous extract have the functions of detoxifying, inhibiting bacteria, relieving pain and diminishing swelling, can reduce the risk of further infection after the cutin of the skin is damaged, and have the functions of cleaning, inhibiting bacteria and preventing infection.
Detailed Description
Example 1
The cutin removing preparation prepared based on the peony extract comprises, by weight, 20 parts of peony active extract, 15 parts of entada phaseoloides aqueous extract, 10 parts of viola drumstick aqueous extract, 10 parts of vetch aqueous extract, 6 parts of rubus biflorus aqueous extract, 5 parts of gorgon fruit aqueous extract, 1 part of leopard aqueous extract and 1 part of gleditsia sinensis aqueous extract.
The preparation method of the peony active extract comprises the following steps:
1.2-3 years old peony, collecting the whole peony, cleaning, drying (drying in the shade), removing main stem, and retaining peony leaf, peony root, peony lateral branch, etc.
2. Raw material treatment
And (3) crushing the raw materials in the step (1) to 20-40 meshes for later use.
3. Preparation of the extract
Acidic oxidation potential water with pH of 2-3.
4. Extraction process
1) Adding the raw materials and the extracting solution into an extracting container according to the material-liquid ratio of 1:8-1: 15.
Rapidly (within 2 min) shearing the material at high speed for 3-5min by adopting a high-speed shearing machine (with the rotating speed of 12000-.
And (3) carrying out solid-liquid separation on the sheared material by adopting vacuum filtration equipment to obtain liquid 1 and residues, repeating the step 2) on the residues for extraction again, carrying out vacuum filtration to obtain liquid 2 after extraction is finished, and combining the two liquids to obtain an extracting solution.
Placing the extractive solution into stainless steel container, and freezing at-10 deg.C for 12 hr.
After freezing, melting at room temperature, vacuum-filtering with medium-speed qualitative filter paper to remove precipitate to obtain clear liquid, and repeating for 2 times to obtain filtrate.
Concentrating the suction filtration liquid obtained in the step 5) by adopting membrane concentration equipment to 1/3-1/4 in volume to obtain concentrated liquid.
2) And (5) freezing and drying the concentrated solution at low temperature to obtain a finished product.
Example 2
The cutin removing preparation prepared based on the peony extract comprises, by weight, 20 parts of peony active extract, 15 parts of entada phaseoloides aqueous extract, 10 parts of viola drumstick aqueous extract, 10 parts of vetch aqueous extract, 6 parts of rubus biflorus aqueous extract, 5 parts of gorgon fruit aqueous extract, 1 part of leopard aqueous extract and 1 part of gleditsia sinensis aqueous extract.
The preparation method of the peony active extract is the same as that of example 1.
Example 3
The cutin removing preparation prepared based on the peony extract comprises, by weight, 36 parts of peony active extract, 28 parts of entada phaseoloides aqueous extract, 17 parts of viola drumstick aqueous extract, 13 parts of wild pea aqueous extract, 10 parts of rubus biflorus aqueous extract, 8 parts of gorgon fruit aqueous extract, 4 parts of leopard aqueous extract and 2 parts of gleditsia sinensis aqueous extract.
The preparation method of the peony active extract is the same as that of example 1.
Example 4
The cutin removing preparation prepared based on the peony extract comprises, by weight, 40 parts of peony active extract, 30 parts of entada phaseoloides aqueous extract, 20 parts of viola drumstick aqueous extract, 15 parts of wild pea aqueous extract, 12 parts of rubus biflorus aqueous extract, 10 parts of gorgon fruit aqueous extract, 5 parts of leopard aqueous extract and 3 parts of gleditsia sinensis aqueous extract.
The preparation method of the peony active extract is the same as that of example 1.

Claims (10)

1. The cutin removing preparation prepared based on the peony extract is characterized by comprising, by weight, 20-40 parts of a peony active extract, 15-30 parts of an entada phaseoloides aqueous extract, 10-20 parts of a viola drumstick aqueous extract and 10-15 parts of a vetch aqueous extract.
2. The exfoliating formulation of claim 1 further comprising at least one of an aqueous extract of rubus biflorus, an aqueous extract of pachyrhizus, an aqueous extract of leopard, and an aqueous extract of honey locust.
3. The exfoliating preparation according to claim 1, which comprises 20 to 40 parts by weight of peony active extract, 15 to 30 parts by weight of entada phaseoloides aqueous extract, 10 to 20 parts by weight of viola drumstick aqueous extract, 10 to 15 parts by weight of vetch aqueous extract, 6 to 12 parts by weight of rubus davidianus aqueous extract, 5 to 10 parts by weight of cephalous canadensis aqueous extract, 1 to 5 parts by weight of leopard aqueous extract and 1 to 3 parts by weight of gleditsia sinensis aqueous extract.
4. The exfoliating preparation according to claim 1, which comprises 30 parts by weight of peony active extract, 25 parts by weight of entada phaseoloides aqueous extract, 15 parts by weight of viola drumstick aqueous extract, 13 parts by weight of vetch aqueous extract, 8 parts by weight of rubus biflorus aqueous extract, 8 parts by weight of cephalous aqueous extract, 3 parts by weight of leopard aqueous extract and 2 parts by weight of gleditsia sinensis aqueous extract.
5. The exfoliating preparation of claim 1, wherein the peony active extract is prepared by a method comprising:
s01, selecting a 2-3 year old whole peony seedling, cleaning, drying, removing a main stem, and keeping peony leaves, peony roots and peony lateral branches, which are used as raw materials;
s02, crushing the raw materials to 20-40 meshes to obtain raw material powder;
s03, placing the obtained raw material powder and the obtained extracting solution into an extracting container according to the material-liquid ratio of 1:8-1:15, and carrying out high-speed shearing on the raw material for 3-5min by adopting a high-speed shearing machine to obtain a material mixture;
s04, performing solid-liquid separation on the material mixture by using vacuum filtration equipment to obtain filtrate and residues;
s05, placing the filtrate in a stainless steel container, freezing for 10-15 hours at the temperature of-8 to-12 ℃, thawing at room temperature after freezing, performing vacuum filtration by adopting medium-speed qualitative filter paper, and removing precipitates to obtain a filtrate;
and S06, concentrating the obtained suction filtration liquid by adopting membrane concentration equipment to obtain 1/3-1/4 of the original volume, further obtaining concentrated liquid, and freeze-drying the concentrated liquid at low temperature to obtain a finished product.
6. The exfoliating preparation of claim 5, wherein in step S02, the ratio of material to liquid is 1: 12.
7. The exfoliating preparation of claim 5, wherein in step S04, the temperature condition is-10 ℃; the freezing time was 12 h.
8. The exfoliating formulation of claim 5 wherein in step S05, the concentrated volume is 1/3 of the original volume.
9. The exfoliating preparation of claim 5 wherein in step S03, the extract is selected from electrolyzed oxidizing water.
10. The exfoliating preparation of claim 5, wherein in step S02, the particle size of the raw material powder is 30 mesh.
CN202110208710.3A 2021-02-24 2021-02-24 Exfoliating preparation prepared based on peony extract Pending CN112842961A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113262184A (en) * 2021-06-02 2021-08-17 山西纳安生物科技股份有限公司 Special peony active extract for cleaning daily chemicals and preparation method thereof
CN113332198A (en) * 2021-06-02 2021-09-03 山西纳安生物科技股份有限公司 Special peony active extract for daily use chemicals and preparation method thereof
CN115300937A (en) * 2022-08-16 2022-11-08 山西纳安健康科技有限公司 Method for extracting active components from moutan bark

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101115493A (en) * 2005-08-12 2008-01-30 河乃建仁 Agent for hair growth
CN106726932A (en) * 2016-12-19 2017-05-31 哈尔滨灵草舒生物科技有限公司 A kind of peony promoting blood circulation for regulating menstruation shower cream and preparation method thereof
CN107308035A (en) * 2017-06-01 2017-11-03 佛山市汇汾化妆品科技有限公司 The beautiful skin BB frosts of one kind maintenance
CN109568232A (en) * 2019-01-22 2019-04-05 广州博科健康科技集团有限公司 A kind of clean face powder of whitening and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101115493A (en) * 2005-08-12 2008-01-30 河乃建仁 Agent for hair growth
CN106726932A (en) * 2016-12-19 2017-05-31 哈尔滨灵草舒生物科技有限公司 A kind of peony promoting blood circulation for regulating menstruation shower cream and preparation method thereof
CN107308035A (en) * 2017-06-01 2017-11-03 佛山市汇汾化妆品科技有限公司 The beautiful skin BB frosts of one kind maintenance
CN109568232A (en) * 2019-01-22 2019-04-05 广州博科健康科技集团有限公司 A kind of clean face powder of whitening and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113262184A (en) * 2021-06-02 2021-08-17 山西纳安生物科技股份有限公司 Special peony active extract for cleaning daily chemicals and preparation method thereof
CN113332198A (en) * 2021-06-02 2021-09-03 山西纳安生物科技股份有限公司 Special peony active extract for daily use chemicals and preparation method thereof
CN115300937A (en) * 2022-08-16 2022-11-08 山西纳安健康科技有限公司 Method for extracting active components from moutan bark

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Application publication date: 20210528

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