CN112825853B

CN112825853B - Cockroach-killing gel bait with high safety and preparation method thereof

Info

Publication number: CN112825853B
Application number: CN202110040500.8A
Authority: CN
Inventors: 张向荣; 张瑜; 高少伟; 陈佳福; 陈文磊
Original assignee: Fujian Goldeer Daily Chemical Co ltd
Current assignee: Fujian Goldeer Daily Chemical Co ltd
Priority date: 2021-01-13
Filing date: 2021-01-13
Publication date: 2022-03-15
Anticipated expiration: 2041-01-13
Also published as: CN112825853A

Abstract

The invention relates to the technical field of pesticides, and particularly relates to a cockroach-killing gel bait with high safety and a preparation method thereof. The cockroach-killing gel bait with high safety comprises, by weight, 0.15-0.6% of pesticide, 0.2-1% of xanthan gum, 4-15% of sugar, 1-5% of a humectant, 20-40% of a filler, 0.5-1% of a preservative and the balance of water. The cockroach-killing gel bait has the characteristics of good palatability and drug effect, good stability, no pungent smell, no environmental pollution, high efficiency, low toxicity and the like, and can be exposed in the environment for a long time.

Description

Cockroach-killing gel bait with high safety and preparation method thereof

Technical Field

The invention relates to the technical field of pesticides, and particularly relates to a cockroach-killing gel bait with high safety and a preparation method thereof.

Background

Cockroaches are an important class of sanitary pests that carry a variety of pathogens and pose a significant threat to human health. At present, the main means for preventing and controlling cockroaches is chemical prevention and control, such as adopting smoke agent, aerosol, powder and the like. However, the traditional cockroach killing drug formulations have the defects of short duration, large smell, high toxicity and the like. The cockroach killing gel bait overcomes the defects of traditional cockroach killing drug formulations such as aerosol, powder, smoke agent and the like, has the advantages of convenience in use, safety, environmental protection and the like, active foraging of cockroaches is the premise of taking effect of the cockroach killing gel bait, but some attractants of the conventional cockroach killing gel bait are wrapped and are difficult to diffuse out so as to achieve the effect of attracting the cockroaches. And some existing cockroach-killing gel baits also have the defect of poor stability, and when the cockroach-killing gel bait is exposed in the environment for a long time, phenomena of thinning, color change, bleeding, layering and the like occur, so that the pesticide effect of the cockroach-killing gel bait is reduced.

Disclosure of Invention

In order to solve the technical problems, the first aspect of the invention provides a cockroach gel bait with high safety, and the cockroach gel bait comprises, by weight, 0.15-0.6% of pesticide, 0.2-1% of xanthan gum, 4-15% of sugar, 1-5% of a humectant, 20-40% of a filler, 0.5-1% of a preservative, and the balance of water.

As a preferable technical scheme, the pesticide is at least one of imidacloprid, fenamiphos, pirimiphos-methyl, fipronil, abamectin, indoxacarb, hydramethylnon and beta-cypermethrin.

In a preferred embodiment of the present invention, the sugar is at least one of fructose, sucrose, maltose and glucose.

According to a preferable technical scheme of the invention, the humectant is at least one of glycerin, propylene glycol, sorbitol, amino acid, polypeptide, sodium lactate, urea, hydroxyethyl urea and hexylene glycol.

As a preferable technical scheme of the invention, the humectant is a mixture of polypeptide, glycerol and hydroxyethyl urea.

According to a preferable technical scheme of the invention, the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is (1.6-2.2): 1.

in a preferred technical scheme of the invention, the starch is at least one of corn starch, tapioca starch and potato starch.

In a preferred embodiment of the present invention, the filler further comprises diatomaceous earth.

In a preferred embodiment of the present invention, the filler further comprises an HY-type molecular sieve.

The second aspect of the invention provides a preparation method of a cockroach-killing gel bait with high safety, and the preparation method of the cockroach-killing gel bait comprises the following steps:

s1, adding the pesticide raw material into water, and stirring until the pesticide raw material is completely dispersed;

s2, adding cyclodextrin and xanthan gum into the water mixed solution of imidacloprid, stirring and heating in ultrasonic oscillation, and reacting until crystals appear under a microscope;

and S3, cooling the reaction solution, sequentially adding the filler, the humectant, the preservative and the sugar, and uniformly stirring to obtain the cockroach-killing gel bait.

The invention has the following beneficial effects:

1. the cockroach killing gel bait provided by the invention has fluidity and is convenient to fill, after the gel is filled into the cockroach killing bait box, gel is formed on the surface of the bait, so that the product does not have fluidity but has a moisture preserving effect, the product cannot flow out of the cockroach killing bait box, troubles in transportation and use are avoided, and the palatability of the product is reserved;

2. the product has the characteristics of good palatability, no pungent smell, no environmental pollution, high efficiency, low toxicity and the like;

3. the feeding attractant in the gel bait attracts cockroaches to eat before, the bait provides good palatability, bad smell is covered, the cockroaches are attracted to eat actively, and the goal of killing the cockroaches is achieved by matching with insecticidal components;

4. the invention can kill cockroaches which have drug resistance, and has good prevention and control effect;

5. the cockroach-killing gel bait has the characteristics of safety, environmental protection, high efficiency, low toxicity and convenient use, and the raw materials of the cockroach-killing gel bait are mostly low in price, the preparation method is simple and easy to implement, and the production cost can be greatly reduced.

Detailed Description

The invention will be further understood by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. To the extent that a definition of a particular term disclosed in the prior art is inconsistent with any definition provided in the present disclosure, the definition of the term provided in the present disclosure controls.

As used herein, a feature that does not define a singular or plural form is also intended to include a plural form of the feature unless the context clearly indicates otherwise. It will be further understood that the term "prepared from …," as used herein, is synonymous with "comprising," including, "comprising," "having," "including," and/or "containing," when used in this specification means that the recited composition, step, method, article, or device is present, but does not preclude the presence or addition of one or more other compositions, steps, methods, articles, or devices. Furthermore, the use of "preferred," "preferably," "more preferred," etc., when describing embodiments of the present invention, is meant to refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. In addition, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention.

The first aspect of the invention provides a cockroach gel bait with high safety, which comprises, by weight, 0.15-0.6% of pesticide, 0.2-1% of xanthan gum, 4-15% of sugar, 1-5% of humectant, 20-40% of filler, 0.5-1% of preservative and the balance of water.

In a preferred embodiment, the raw materials of the cockroach-killing gel bait comprise, by weight, 0.26-0.48% of pesticide, 0.5-0.8% of xanthan gum, 7-10% of sugar, 2-4% of a humectant, 25-38% of a filler, 0.6-0.8% of a preservative, and the balance of water.

In a preferred embodiment, the raw materials of the cockroach-killing gel bait comprise, by weight, 0.37% of pesticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of humectant, 32% of filler, 0.7% of preservative and the balance of water.

Pesticide raw material

In one embodiment, the pesticide is at least one of imidacloprid, fenamiphos, pirimiphos-methyl, fipronil, abamectin, indoxacarb, hydramethylnon and beta-cypermethrin.

In a preferred embodiment, the pesticide is imidacloprid and fipronil.

In one embodiment, the weight ratio of the imidacloprid to fipronil is (2.5-6.7): 1.

in a preferred embodiment, the weight ratio of the imidacloprid to the fipronil is (3.3-5): 1; further preferably, the weight ratio of the imidacloprid to the fipronil is 4.3: 1.

in one embodiment, the imidacloprid is purchased from Jiangsu Youjia plant protection, Inc.

In one embodiment, the fipronil is purchased from Jiangsu Youjia plant protection, Inc.

Fipronil is a phenyl pyrazole pesticide, in particular to 5-amino-1- (2, 6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethyl sulfinyl, the DT50 of which is about 28 days and is slowly degraded under the sunlight, and the action mechanism of the fipronil is to block the chloride metabolism controlled by the gamma-aminobutyric acid of insects, so the fipronil has high insecticidal activity on important pests such as aphids, leafhoppers, plant hoppers, lepidoptera larvae, flies, coleoptera and the like, has no phytotoxicity on crops, and has high safety.

Imidacloprid is a nitromethylene systemic insecticide, belongs to chloronicotinyl insecticide nitre, is an action body of a nicotine acetylcholine receptor, interferes the motor nervous system of pests to cause the transmission failure of chemical signals, has no problem of cross resistance, and has high degree and good insecticidal effect.

The applicant finds that the cockroach-killing gel bait has good drug effect at high and low temperatures by using a certain proportion of imidacloprid and fipronil in the system of the invention to realize mutual synergistic effect.

Cyclodextrin

In one embodiment, the cyclodextrin is purchased from biotechnology, Inc. of Dongxin, Fujian.

Cyclodextrin is cyclodextrin (beta-cyclodextrin is short for beta-CD) which is a product generated by acidolysis and cyclization of starch. It can envelop various compound molecules, increase the stability of enveloped matter to light, heat and oxygen, and change the physical and chemical properties of enveloped matter. The cyclodextrin inclusion agent is used for inclusion of the insecticide, so that the stability of the cockroach-killing gel bait can be improved to a certain extent.

Xanthan gum

In one embodiment, the xanthan gum is purchased from biotechnology, Inc., Dongxin, Fujian.

Xanthan gum (Xanthan gum), also known as Xanthan gum, is a broad-spectrum microbial extracellular polysaccharide produced by fermentation engineering of Xanthomonas campestris (Xanthomonas campestris) with carbohydrate as the main raw material (such as corn starch). Xanthan gum has the general properties of long chain polymers, but it contains more functional groups than general polymers and shows unique properties under specific conditions. In the system of the present invention, xanthan gum may serve a certain binding function.

Candy

In order to provide the cockroach-killing gel bait with certain attraction and feeding stimulation, in one embodiment, the sugar is at least one of fructose, sucrose, maltose and glucose.

In a preferred embodiment, the sugars are fructose and maltose.

In one embodiment, the weight ratio of fructose to maltose is (2.6-5.2): 1.

in a preferred embodiment, the weight ratio of fructose to maltose is (3.5-4.2): 1; further preferably, the weight ratio of fructose to maltose is 3.8: 1.

in one embodiment, the fructose is crystalline fructose.

In one embodiment, the crystalline fructose is purchased from fujianzi heiyi pharmaceutical trade company, ltd.

In one embodiment, the maltose is an oligomaltose.

In one embodiment, the malto-oligosaccharide is purchased from puzzling pharmaceutical trade, ltd.

The applicant finds that the palatability of the cockroach-killing gel bait is better when fructose and maltose are used in a certain ratio in the system, and the stability of the cockroach-killing gel bait can be improved to a certain extent when the fructose is used, probably because the fructose is a monosaccharide, a small part of the fructose is degraded into 5-hydroxymethyl-2 furfural serving as an active monomer under the action of the diatomite and the H-type molecular sieve in the invention, and the 5-hydroxymethyl-2 furfural can form a polymer with a binding property with substances with hydroxyl groups, starch, xanthan gum and the like in the system under the action of the H-type molecular sieve (catalysis), so that the binding property of the cockroach-killing gel bait is improved, and the stability of the cockroach-killing gel bait is improved.

Moisture-retaining agent

In one embodiment, the humectant is at least one of glycerin, propylene glycol, sorbitol, an amino acid, a polypeptide, sodium lactate, urea, hydroxyethyl urea, hexylene glycol.

In a preferred embodiment, the humectant is a mixture of a polypeptide, glycerin, hydroxyethyl urea.

In one embodiment, the weight ratio of glycerol, polypeptide, hydroxyethyl urea is 1: (1.5-2): (1-1.5); further preferably, the weight ratio of the glycerol to the polypeptide to the hydroxyethyl urea is 1: 1.8: 1.3.

in one embodiment, the polypeptide is at least one of a soy polypeptide, a walnut polypeptide, a momordica polypeptide; further preferably, the polypeptide is a soybean polypeptide.

In one embodiment, the soy polypeptide is purchased from Sammlung Biotech, Inc.

In one embodiment, the hydroxyethyl urea is purchased from Airitong New materials, Inc. of Shandong.

In one embodiment, the glycerol is purchased from new materials, Airitong, Shandong.

In the system, the polypeptide, the glycerol and the hydroxyethyl urea are used for mutual synergistic action, so that the cockroach-killing gel bait has higher stability. Probably because the polypeptide, the glycerol and the hydroxyethyl urea have good moisture retention and good antifreezing property through mutual synergistic action, the glycerol and the hydroxyethyl urea can well interact with the 5-hydroxymethyl-2 furfural, and the performance of the cockroach-killing gel bait for trapping cockroaches is improved by adopting the synergistic action of the soybean polypeptide and the saccharides in the system.

Filler

In one embodiment, the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is (1.6-2.2): 1.

in a preferred embodiment, the weight ratio of starch to gelatin is 1.8: 1.

in one embodiment, the starch is at least one of corn starch, tapioca starch, potato starch; further preferably, the starch is corn starch.

In one embodiment, the corn starch is purchased from chemical Limited, Dennauno.

In one embodiment, the gelatin is purchased from Xiamen Haiyou gelatin, Inc.

In a preferred embodiment, the filler further comprises diatomaceous earth.

In one embodiment, the weight of the diatomite is 13-18% of the weight of the filler; more preferably, the weight of the diatomite is 15% of the weight of the filler.

In one embodiment, the diatomaceous earth is purchased from environmental new materials, Inc., Yuantong, Guangzhou.

The applicant finds that the addition of the diatomite in the system can enable the cockroach gel bait to have good stability and drug effect. Probably because the diatomite is weakly acidic, the imidacloprid and fipronil have better drug effect under the condition of weak acidity.

In a preferred embodiment, the filler further comprises an HY type molecular sieve.

In one embodiment, the weight of the HY type molecular sieve is 18-25% of the weight of the filler; more preferably, the HY-type molecular sieve is 22% by weight of the filler.

In one embodiment, the HY type molecular sieves are available from highly Natural environmental protection technologies (Dalian) Inc.

When the cyclodextrin is used as the ingredient inclusion agent to encapsulate the insecticide filling agent, the cyclodextrin can only coat molecules with the size similar to that of a cavity of the cyclodextrin, and the defect that the insecticide effect of the insecticide cannot be well released exists. The applicant finds that the addition of the HY molecular sieve can well release the pesticide raw materials, achieve good pesticide effect and increase the stability and palatability of the cockroach killing gel bait. Probably because the HY type molecular sieve has a plurality of micropores, the gelatin can generate cross-linking reaction in the slow release process to form a slow release layer, and the interaction of the gelatin and the gelatin can well release sugar, thereby increasing the palatability of the cockroach-killing gel bait.

Preservative

The preservative is not limited, and preservatives suitable for use in a gel bait system are all suitable for use in the present system.

Examples of preservatives include sodium benzoate, potassium sorbate and sodium diacetate.

In a preferred embodiment, the preservatives are potassium sorbate and sodium diacetate; wherein the weight ratio of potassium sorbate (CAS number: 24634-61-5) to sodium diacetate (CAS number: 129-96-5) is 2: 1.

the applicant finds that when potassium sorbate and sodium diacetate are used as preservatives, the gel bait not only has the function of corrosion prevention, but also has the effects of fragrance improvement and freshness improvement, and can increase the palatability of the gel bait for killing cockroaches by interacting with sugar in a system.

Water (W)

The source of the water is not limited, and may be tap water, distilled water, deionized water, or the like.

In one embodiment, the water is deionized water.

Several specific examples of the present invention are given below, but the present invention is not limited by the examples.

In addition, the starting materials in the present invention are all commercially available unless otherwise specified.

Examples

Example 1

The embodiment 1 of the invention specifically provides a cockroach-killing gel bait with high safety, and the cockroach-killing gel bait comprises, by weight, 0.26% of pesticide, 0.8% of xanthan gum, 8% of sugar, 2.9% of a humectant, 38% of a filler, 0.6% of a preservative and the balance of water;

the pesticide raw material is imidacloprid and fipronil; the weight ratio of the imidacloprid to the fipronil is 3.3: 1;

the sugar is fructose and maltose; the weight ratio of the fructose to the maltose is 3.5: 1; the fructose is crystalline fructose; the maltose is oligomeric maltose;

the humectant is a mixture of polypeptide, glycerol and hydroxyethyl urea; the weight ratio of the glycerol to the polypeptide to the hydroxyethyl urea is 1: 1.5: 1; the polypeptide is soybean polypeptide;

the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is 1.6: 1; the filler further comprises diatomaceous earth; the weight of the diatomite is 13 percent of the weight of the filler; the filler also comprises an HY type molecular sieve; the weight of the HY type molecular sieve is 18 percent of the weight of the filler;

the preservative is potassium sorbate and sodium diacetate; wherein the weight ratio of potassium sorbate (CAS number: 24634-61-5) to sodium diacetate (CAS number: 129-96-5) is 2: 1;

the water is deionized water.

The preparation method of the cockroach-killing gel bait comprises the following steps: s1, adding the pesticide raw material into water, and stirring until the pesticide raw material is completely dispersed; s2, adding cyclodextrin and xanthan gum into the water mixed solution of imidacloprid, stirring and heating in ultrasonic oscillation, and reacting until crystals appear under a microscope; and S3, cooling the reaction solution, sequentially adding the filler, the humectant, the preservative and the sugar, and uniformly stirring to obtain the cockroach-killing gel bait.

The imidacloprid is purchased from Jiangsu Youjia plant protection Co., Ltd; the fipronil is purchased from Jiangsu Youjia plant protection Co., Ltd; the cyclodextrin is purchased from eastern Xin Shuo Biotech Co., Ltd, Fujian; the xanthan gum is purchased from Dongxin Biotech, Inc. of Fujian; the crystalline fructose is purchased from Fujianzhizi Youjin Yizhihua medicine trade Co Ltd; the malto-oligosaccharide is purchased from Fujianzhi Youyi pharmaceutical trade company Limited; the soybean polypeptide is purchased from Xiamen Shengmiuo Biotechnology Co., Ltd; the hydroxyethyl urea is purchased from New materials, Inc. of Airitong in Shandong; the glycerol is purchased from New materials, Inc. of Airitong in Shandong; the corn starch is purchased from chemical Limited, Dennuo, of Jinan province. The gelatin is purchased from Xiamen Haiyou gelatin Co Ltd; the diatomite is purchased from environmental protection new materials, Inc. of Guangzhou Yuantong; the HY type molecular sieve is purchased from highly natural environmental protection science and technology (Dalian) Co., Ltd.

Example 2

The embodiment 2 of the invention specifically provides a cockroach-killing gel bait with high safety, and the cockroach-killing gel bait comprises, by weight, 0.48% of pesticide, 0.8% of xanthan gum, 7% of sugar, 4% of a humectant, 26% of a filler, 0.8% of a preservative and the balance of water;

the pesticide raw material is imidacloprid and fipronil; the weight ratio of the imidacloprid to the fipronil is 5: 1;

the sugar is fructose and maltose; the weight ratio of the fructose to the maltose is 4.2: 1; the fructose is crystalline fructose; the maltose is oligomeric maltose;

the humectant is a mixture of polypeptide, glycerol and hydroxyethyl urea; the weight ratio of the glycerol to the polypeptide to the hydroxyethyl urea is 1: 2: 1.5; the polypeptide is soybean polypeptide;

the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is 2.2: 1; the filler further comprises diatomaceous earth; the weight of the diatomite is 18 percent of the weight of the filler; the filler also comprises an HY type molecular sieve; the weight of the HY type molecular sieve is 25 percent of the weight of the filler;

the water is deionized water.

The preparation method of the cockroach-killing gel bait is the same as that of example 1.

Example 3

The embodiment 3 of the invention specifically provides a cockroach-killing gel bait with high safety, and the cockroach-killing gel bait comprises, by weight, 0.37% of pesticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of a humectant, 32% of a filler, 0.7% of a preservative and the balance of water;

the pesticide raw material is imidacloprid and fipronil; the weight ratio of the imidacloprid to the fipronil is 4.3: 1;

the sugar comprises fructose and maltose, and the weight ratio of the fructose to the maltose is 3.8: 1; the fructose is crystalline fructose; the maltose is oligomeric maltose;

the humectant is a mixture of polypeptide, glycerol and hydroxyethyl urea; the weight ratio of the glycerol to the polypeptide to the hydroxyethyl urea is 1: 1.8: 1.3; the polypeptide is soybean polypeptide;

the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is 1.8: 1; the filler further comprises diatomaceous earth; the weight of the diatomite is 15% of the weight of the filler; the filler also comprises an HY type molecular sieve; the weight of the HY type molecular sieve is 22 percent of the weight of the filler;

the water is deionized water.

Example 4

The embodiment 4 of the invention specifically provides a cockroach-killing gel bait with high safety, and the cockroach-killing gel bait comprises, by weight, 0.37% of pesticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of a humectant, 32% of a filler, 0.7% of a preservative and the balance of water;

the sugar is sucrose and maltose, and the weight ratio of the sucrose to the maltose is 3.8: 1; the maltose is oligomeric maltose;

the water is deionized water.

The imidacloprid is purchased from Jiangsu Youjia plant protection Co., Ltd; the fipronil is purchased from Jiangsu Youjia plant protection Co., Ltd; the cyclodextrin is purchased from eastern Xin Shuo Biotech Co., Ltd, Fujian; the xanthan gum is purchased from Dongxin Biotech, Inc. of Fujian; the malto-oligosaccharide is purchased from Fujianzhi Youyi pharmaceutical trade company Limited; the soybean polypeptide is purchased from Xiamen Shengmiuo Biotechnology Co., Ltd; the hydroxyethyl urea is purchased from New materials, Inc. of Airitong in Shandong; the glycerol is purchased from New materials, Inc. of Airitong in Shandong; the corn starch is purchased from chemical Limited of Jinnno, Jinan; the gelatin is purchased from Xiamen Haiyou gelatin Co. The diatomite is purchased from environmental protection new materials, Inc. of Guangzhou Yuantong; the HY type molecular sieve is purchased from highly natural environmental protection science and technology (Dalian) Co., Ltd.

Example 5

The embodiment 5 of the invention specifically provides a cockroach-killing gel bait with high safety, and the cockroach-killing gel bait comprises, by weight, 0.37% of pesticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of a humectant, 32% of a filler, 0.7% of a preservative and the balance of water;

the sugar is fructose, and the fructose is crystalline fructose;

the water is deionized water.

The imidacloprid is purchased from Jiangsu Youjia plant protection Co., Ltd; the fipronil is purchased from Jiangsu Youjia plant protection Co., Ltd; the cyclodextrin is purchased from eastern Xin Shuo Biotech Co., Ltd, Fujian; the xanthan gum is purchased from Dongxin Biotech, Inc. of Fujian; the crystalline fructose is purchased from Fujianzhizi Youjin Yizhihua medicine trade Co Ltd; the soybean polypeptide is purchased from Xiamen Shengmiuo Biotechnology Co., Ltd; the hydroxyethyl urea is purchased from New materials, Inc. of Airitong in Shandong; the glycerol is purchased from New materials, Inc. of Airitong in Shandong; the corn starch is purchased from chemical Limited of Jinnno, Jinan; the gelatin is purchased from Xiamen Haiyou gelatin Co. The diatomite is purchased from environmental protection new materials, Inc. of Guangzhou Yuantong; the HY type molecular sieve is purchased from highly natural environmental protection science and technology (Dalian) Co., Ltd.

Example 6

Embodiment 6 of the invention specifically provides a cockroach-killing gel bait with high safety, which comprises the following raw materials, by weight, 0.37% of pesticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of a humectant, 32% of a filler, 0.7% of a preservative and the balance of water;

the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is 1.8: 1; the filler also comprises an HY type molecular sieve; the weight of the HY type molecular sieve is 22 percent of the weight of the filler;

the water is deionized water.

The imidacloprid is purchased from Jiangsu Youjia plant protection Co., Ltd; the fipronil is purchased from Jiangsu Youjia plant protection Co., Ltd; the cyclodextrin is purchased from eastern Xin Shuo Biotech Co., Ltd, Fujian; the xanthan gum is purchased from Dongxin Biotech, Inc. of Fujian; the crystalline fructose is purchased from Fujianzhizi Youjin Yizhihua medicine trade Co Ltd; the malto-oligosaccharide is purchased from Fujianzhi Youyi pharmaceutical trade company Limited; the soybean polypeptide is purchased from Xiamen Shengmiuo Biotechnology Co., Ltd; the hydroxyethyl urea is purchased from New materials, Inc. of Airitong in Shandong; the glycerol is purchased from New materials, Inc. of Airitong in Shandong; the corn starch is purchased from chemical Limited, Dennuo, of Jinan province. The gelatin is purchased from Xiamen Haiyou gelatin Co Ltd; the HY type molecular sieve is purchased from highly natural environmental protection science and technology (Dalian) Co., Ltd.

Example 7

Embodiment 7 of the present invention specifically provides a cockroach gel bait with high safety, wherein the cockroach gel bait comprises, by weight, 0.37% of an insecticide, 0.65% of xanthan gum, 8.6% of sugar, 3% of a humectant, 32% of a filler, 0.7% of a preservative, and the balance of water;

the filler comprises starch and gelatin, and the weight ratio of the starch to the gelatin is 1.8: 1; the filler further comprises diatomaceous earth; the weight of the diatomite is 15% of the weight of the filler;

the water is deionized water.

The imidacloprid is purchased from Jiangsu Youjia plant protection Co., Ltd; the fipronil is purchased from Jiangsu Youjia plant protection Co., Ltd; the cyclodextrin is purchased from eastern Xin Shuo Biotech Co., Ltd, Fujian; the xanthan gum is purchased from Dongxin Biotech, Inc. of Fujian; the crystalline fructose is purchased from Fujianzhizi Youjin Yizhihua medicine trade Co Ltd; the malto-oligosaccharide is purchased from Fujianzhi Youyi pharmaceutical trade company Limited; the soybean polypeptide is purchased from Xiamen Shengmiuo Biotechnology Co., Ltd; the hydroxyethyl urea is purchased from New materials, Inc. of Airitong in Shandong; the glycerol is purchased from New materials, Inc. of Airitong in Shandong; the corn starch is purchased from chemical Limited, Dennuo, of Jinan province. The gelatin is purchased from Xiamen Haiyou gelatin Co Ltd; the diatomite is purchased from environmental protection new materials, Inc. of Guangzhou Yuantong.

Performance testing

1. Palatability testing: taking 100 healthy German cockroaches (each half of male and female), fasting without water prohibition, moving the healthy German cockroaches into a glass square box (100cm multiplied by 100cm) after 24 hours, placing an egg rack in the middle, placing soaked sponges beside the egg rack after test insects are all normal, weighing 3g of the cockroach-killing gel bait in the examples 1-7, respectively placing the gel bait on filter paper, randomly placing the gel bait in 7 corners of the square box, plugging and releasing flying holes, weighing the weight of the rest gel bait after 24 hours, calculating the food intake, repeating the test for 3 times, and averaging;

2. and (3) testing the indoor drug effect: 30 German cockroaches (male and female halves) are put into a test square box (100cm multiplied by 100cm) to be plugged and released into the flying holes. After the test insects recovered to normal activities, 10g of cockroach-killing gel bait (experiments are respectively carried out) according to examples 1 to 7 was placed in one corner of the box, the feed for the German cockroach was placed in the opposite corner, and a culture dish containing a soaked cotton ball was placed in the center. The death condition of the test insects is observed day by day, the dead insects are taken out and counted, the test is continuously observed until 12 days after the bait feeding, the test is repeated for 3 times, and the average value is removed. Evaluation criteria: after 12 days of feeding, the death rate of the cockroaches is 100 percent, and the drug effect is A grade; after 12 days of feeding, the death rate of the cockroaches is more than or equal to 90 percent and less than 100 percent, and the drug effect is B grade; after 12 days of feeding, the death rate of the cockroaches is less than 90, and the drug effect is grade C.

3. And (3) stability testing: respectively taking 100 groups of the cockroach-killing gel bait of the embodiment 1-7, sealing, placing in a constant-temperature oven at the temperature of (54 +/-2 ℃), and observing the physical stability of the gel bait after thermal storage for 15 days; physical stability was also observed after 30 days of administration in the natural environment. Evaluation criteria: after the test, the cockroach-killing gel bait with the concentration of more than or equal to 95 groups does not have the phenomena of thinning, color change, bleeding and layering, and has excellent stability; the cockroach-killing gel bait of more than or equal to 80 groups and less than 95 groups does not have the phenomena of thinning, color change, bleeding and layering, and has good stability; the cockroach-killing gel bait of less than 80 groups does not have the phenomena of thinning, color change, bleeding and layering, and has poor stability.

The test results are shown in table 1:

TABLE 1

As can be seen from the test results of table 1, the cockroach-killing gel bait of the present invention has good palatability and drug efficacy, and also has good stability and can be exposed to the environment for a long time.

The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims

1. The cockroach-killing gel bait with high safety is characterized by comprising, by weight, 0.15-0.6% of pesticide, 0.2-1% of xanthan gum, 4-15% of sugar, 1-5% of a humectant, 20-40% of a filler, 0.5-1% of a preservative and the balance of water;

the pesticide raw material is imidacloprid and fipronil; the weight ratio of the imidacloprid to the fipronil is (2.5-6.7): 1;

the filler comprises starch, gelatin, diatomite and an HY type molecular sieve, wherein the weight ratio of the starch to the gelatin is (1.6-2.2): 1; the weight of the diatomite is 13-18% of that of the filler; the weight of the HY molecular sieve is 18-25% of the weight of the filler;

the sugar is fructose and maltose; the weight ratio of the fructose to the maltose is (2.6-5.2): 1.

2. the cockroach gel bait with high safety according to claim 1, wherein the humectant is at least one of glycerin, propylene glycol, sorbitol, amino acid, polypeptide, sodium lactate, urea, hydroxyethyl urea, and hexylene glycol.

3. The cockroach gel bait with high safety according to claim 2, wherein the humectant is a mixture of polypeptide, glycerin and hydroxyethyl urea.

4. The cockroach gel bait with high safety according to claim 1, wherein the starch is at least one of corn starch, tapioca starch and potato starch.

5. The preparation method of the cockroach-killing gel bait with high safety according to any one of claims 1 to 4, wherein the preparation method of the cockroach-killing gel bait comprises the following steps: