CN112823890B - Real-time fluorescence quantitative PCR instrument - Google Patents
Real-time fluorescence quantitative PCR instrument Download PDFInfo
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- CN112823890B CN112823890B CN202010750074.2A CN202010750074A CN112823890B CN 112823890 B CN112823890 B CN 112823890B CN 202010750074 A CN202010750074 A CN 202010750074A CN 112823890 B CN112823890 B CN 112823890B
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- 238000003753 real-time PCR Methods 0.000 title claims abstract description 48
- 238000001514 detection method Methods 0.000 claims abstract description 80
- 238000006243 chemical reaction Methods 0.000 claims description 15
- 230000017525 heat dissipation Effects 0.000 claims description 5
- 238000010586 diagram Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 5
- 238000004891 communication Methods 0.000 description 4
- 230000002159 abnormal effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The application discloses a real-time fluorescence quantitative PCR instrument, which comprises a detection box module for real-time fluorescence quantitative detection and a processor for collecting and processing the signals from the detection box module, wherein the detection box module is connected with the processor through a quick-connection data interface, and the detection box module is arranged in multiple layers.
Description
Technical Field
The application belongs to the field of detection instruments, and particularly relates to a real-time fluorescence quantitative PCR instrument.
Background
The reaction cartridge type real-time fluorescent quantitative PCR apparatus generally includes a reaction cartridge module for performing PCR quantitative detection and a processor for data processing, and in general, the cartridge position of each reaction cartridge type real-time fluorescent quantitative PCR apparatus is fixed and limited, for example, the cartridge position may be 4, 8 or 16, and based on the existing arrangement and installation manner, the cartridge number of the reaction cartridge module is limited, and it is difficult to perform simultaneous detection of a large number of samples, resulting in limited detection efficiency.
In addition, the reaction box module in the existing reaction box type real-time fluorescence quantitative PCR instrument is fixedly arranged on the PCB of the processor through the positioning bracket and the frame, and the connection position of the positioning bracket and the frame is positioned inside the shell of the processor, so that if the reaction box module is replaced, the shell needs to be disassembled first, and then the fixing bracket is opened to take out the reaction box module from the slot of the circuit board, so that the operation is complex, and other parts are easy to damage.
Disclosure of Invention
In order to solve at least one of the problems, the application provides a real-time fluorescence quantitative PCR instrument, which comprises a detection box module for real-time fluorescence quantitative detection and a processor for collecting and processing the signals from the detection box module, wherein the detection box module is connected with the processor through a quick-connection data interface, and the detection box module is arranged in multiple layers.
The application aims to provide a real-time fluorescence quantitative PCR instrument, which comprises a detection box module 1 for real-time fluorescence quantitative detection and a processor 2 for collecting and processing the fluorescence quantitative detection from the detection box module, wherein a first quick-connection data interface 3 is arranged on the processor 2, a second quick-connection data interface 4 is arranged on the detection box module 1, the detection box module 1 is connected with the processor 2 through the first quick-connection data interface 3 and the second quick-connection data interface 4, and the detection box module 1 is arranged in a plurality of layers.
In one possible manner, each layer of the cartridge modules 1 is arranged in a straight line, a curve, or a ring shape, so that space is fully utilized and detection efficiency is improved.
Optionally, the shapes of the layers of the detection box modules 1 can be the same or different, so as to adapt to the use environment of the real-time fluorescence timing PCR instrument.
For example, the multi-layered cartridge module 1 may be stacked to form a planar wall shape, a curved wall shape, a regular hexagonal cylinder shape, a cylindrical shape, or other abnormal shape, etc.
In one implementation manner, two adjacent layers of detection box modules 1 are distributed in a staggered manner, so that the mutual interference between the detection box modules 1 in the sample injection process is reduced, the heat dissipation space can be increased, and the stability of the detection result is improved.
In one possible manner, the distance between two adjacent cartridge modules 1 in the same layer is at least 15mm, for example, 15mm to 30mm, so as to ensure that each of the cartridge modules 1 can sufficiently dissipate heat.
In one possible embodiment, the cartridge module 1 is flexibly or rigidly connected to the processor via a quick-connect data interface.
In one implementation, the first quick-connect data interface 3 includes a USB interface or an HDMI interface; and/or, the second quick-connect data interface 4 includes a USB interface or an HDMI interface, etc.
In one possible implementation, the real-time fluorescent quantitative PCR instrument further comprises a display 5 for displaying information processed by the processor 2.
Compared with the prior art, the real-time fluorescence quantitative PCR instrument provided by the application can be expanded according to the processing requirement by setting a specific arrangement mode and a data connection mode, specifically, the detection box modules in the real-time fluorescence quantitative PCR instrument provided by the application are arranged in multiple layers, and the number of the detection box modules can be specifically set according to the requirement, for example, the number of the detection box modules can be 1, 96 or even more; further, the detection box module is connected with the processor through a quick-connection data interface, so that data communication is realized, and the detection box module can be easily detached, replaced and maintained.
Drawings
FIG. 1 is a schematic diagram showing the front view structure of a preferred real-time fluorescent quantitative PCR apparatus according to the present application;
FIG. 2 shows a right side view of the real-time fluorescent quantitative PCR apparatus shown in FIG. 1;
FIG. 3 shows a left side view of the real-time fluorescent quantitative PCR apparatus shown in FIG. 1;
FIG. 4 shows a top view of the real-time fluorescent quantitative PCR apparatus shown in FIG. 1;
FIG. 5 shows a bottom view of the real-time fluorescent quantitative PCR instrument of FIG. 1;
FIG. 6 shows a schematic perspective view of a processor in the real-time fluorescent quantitative PCR apparatus shown in FIG. 1;
FIG. 7-1 is a schematic perspective view showing a cartridge module;
FIG. 7-2 shows a rear view of the cartridge module shown in FIG. 7-1;
FIG. 7-3 is a schematic diagram showing the position of the cartridge module shown in FIG. 7-1 and the processor in the real-time fluorescent quantitative PCR apparatus shown in FIG. 6 immediately before the processor is connected;
FIG. 7-4 is a schematic diagram showing the position of the cartridge module shown in FIG. 7-1 after the processor in the real-time fluorescence quantitative PCR apparatus shown in FIG. 6 is quickly connected;
FIG. 8 shows a schematic perspective view of the real-time fluorescent quantitative PCR apparatus shown in FIG. 1;
FIG. 9 is a schematic diagram showing the perspective structure of another real-time fluorescent quantitative PCR apparatus according to the present application;
FIG. 10 is a schematic diagram showing the perspective structure of another real-time fluorescent quantitative PCR apparatus according to the present application.
Description of the reference numerals
The device comprises a 1-detection box module, a 11-reaction box cover, a 12-indicator lamp, a 13-heat radiation port, a 2-processor, a 21-power connection port, a 22-power button, a 23-total start button, a 24-sub start button, a 25-clamping groove, a 3-first quick-connection data interface, a 4-second quick-connection data interface and a 5-display.
Detailed Description
Reference will now be made in detail to exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, the same numbers in different drawings refer to the same or similar elements, unless otherwise indicated. The implementations described in the following exemplary examples do not represent all implementations consistent with the invention. Rather, they are merely examples of methods consistent with aspects of the invention as detailed in the accompanying claims.
The structure and the method of use of the real-time fluorescent quantitative PCR apparatus provided by the application are described in detail below by way of specific examples.
Fig. 1 shows a schematic diagram of a front view structure of a preferred real-time fluorescent quantitative PCR apparatus according to the present application, as shown in fig. 1, the real-time fluorescent quantitative PCR apparatus includes a detection box module 1 for real-time fluorescent quantitative detection and a processor 2 for collecting and processing the signals from the detection box module, the detection box module 1 is connected with the processor 2 through a quick-connection data interface, and the detection box module 1 is provided in multiple layers.
As shown in fig. 1, the real-time fluorescent quantitative PCR instrument further comprises a display 5 for displaying information processed by the processor 2.
In this example, the display may be specifically set at a position according to a space where the real-time fluorescent quantitative PCR apparatus is located, for example, the display may be disposed on the left side or the right side of the processor, may be disposed on the top of the processor, or may be disposed in different rooms separately from the processor, and may be communicated through a data line.
It will be appreciated that the real-time fluorescent quantitative PCR instrument further comprises an information input device (not shown) for inputting specific processing information, e.g. processing parameters etc., to the processor, the information input device comprising a mouse and/or a keyboard etc.
Fig. 2 shows a right side view of the real-time fluorescence quantitative PCR instrument shown in fig. 1, and as shown in fig. 2, a power connection port 21 and a power button 22 for controlling whether the processor 2 is powered on are provided on the processor.
In this example, the cartridge module 1, after being in communication with the processor, obtains electrical energy from the processor, so as to process the sample filled therein according to a preset program.
Fig. 3 shows a left side view of the real-time fluorescence quantitative PCR apparatus shown in fig. 1, and as shown in fig. 3, a total start button 23 for starting the operation of the cartridge modules 1 is further provided on the processor, and after the total start button 23 is turned on, each cartridge module 1 can start to operate.
Optionally, a program for independently controlling whether the detection box modules 1 communicated with the processor 2 start to operate is preset in the processor 2, that is, whether each detection box module 1 starts to operate can be independently controlled by the processor 2, so that each detection box module can independently operate.
Further, an independent sub-start button 24 may be further disposed on each cartridge module 1, so as to separately control the start of the corresponding cartridge module 1, that is, in the case that the total start button and the corresponding sub-start button 24 are simultaneously turned on and triggered by the processor 2, the cartridge module 1 starts to operate, so that each cartridge module can operate independently.
Fig. 4 shows a top view of the real-time fluorescent quantitative PCR apparatus shown in fig. 1, and as shown in fig. 4, a slot 25 for mounting the cartridge module 1 is provided on one side of the processor 2.
Fig. 5 shows a bottom view of the real-time fluorescent quantitative PCR instrument of fig. 1, as shown in fig. 5, the processor 2 can be placed on any available space or plane.
It will be appreciated that fig. 5 shows only one possible solution, and that for a specific usage space, the bottom of the processor may be stepped, annular, etc. to accommodate different usage scenarios.
In this example, each layer of detection box modules 1 may be arranged in a straight line, a curve or a ring, where the curve includes refraction, a wave line, a streamline, etc., and a specific arrangement manner may be specifically set according to a usage space, so that a space is fully utilized, and more detection box modules may be disposed in a limited space, thereby indirectly improving a detection capability and a detection efficiency.
In this example, the arrangement of each layer of the cartridge modules 1 may be set by the shape of the processor 2.
Fig. 6 shows a schematic perspective view of a processor in the real-time fluorescent quantitative PCR apparatus shown in fig. 1, as shown in fig. 6, a slot 25 for fast connecting the detection box module 1 is reserved on the processor 2, and a first fast connecting data interface 3 is provided in the slot 25.
Fig. 7-1 shows a schematic perspective view of a detection box module, as shown in fig. 7-1, the detection box module 1 may be in a hexagonal prism shape, a reaction box cover 11 for adding samples is provided on one side surface of the detection box module 1, an indicator lamp 12 for indicating whether a reaction is started or not and a heat dissipation opening 13 for dissipating heat of the detection box module are further provided on the detection box module 1, wherein the indicator lamp 12 is the same as a visible area of the reaction box cover 11, and the heat dissipation opening 13 is the same as an operable space of the reaction box cover 11.
Fig. 7-2 shows a rear view of the cartridge module shown in fig. 7-1, and a second quick-connect data interface 4 is further provided on the cartridge module 1, as shown in fig. 7-2.
In this example, the second quick-connect data interface 4 is matched with the first quick-connect data interface 3, the detection box module 1 may be flexibly connected or rigidly connected to the processor through the quick-connect data interface, and after the connection, information such as data may be mutually transmitted, where the first quick-connect data interface 3 includes a USB interface or an HDMI interface; and/or the second quick-connect data interface 4 comprises a USB interface or an HDMI interface, etc.
For example, the cartridge module 1 is in direct communication with the processor 2 via the first and second quick-connect data interfaces 3,4, i.e., the cartridge module 1 and the processor 2 may be rigidly connected.
Further, the detection box module 1 may be clamped in the clamping groove 25, and after being clamped in the clamping groove 25, the first quick-connection data interface 3 and the second quick-connection data interface 4 naturally complete the butt joint.
In this example, the flexible connection includes communicating the detection box module 1 and the processor 2 through a data transmission medium such as a data line, and it is understood that at least one end of the used data transmission medium is provided with a quick-connect data interface, so as to implement quick-connect data connection between the processor 2 and the detection box module 1.
FIG. 7-3 shows a schematic diagram of the structure of the cartridge module shown in FIG. 7-1 and the structure of the processor in the real-time fluorescence quantitative PCR apparatus shown in FIG. 6 before the processor is connected, and as shown in FIG. 7-3, the slot 25 is matched with the structure of the cartridge module 1.
Fig. 7-4 shows a schematic diagram of the position structure of the cartridge module shown in fig. 7-1 after the processor in the real-time fluorescent quantitative PCR apparatus shown in fig. 6 is quickly connected, as shown in fig. 7-4, the cartridge module may be just clamped in the clamping groove 25, and after clamping, the cartridge module 1 is difficult to spontaneously fall off.
It will be appreciated that the arrangement of each layer of the cartridge modules 1 may be set in other ways, for example, no slot is provided on the processor 2 for installing the cartridge modules 1, but only a sufficient number of quick-connect data interfaces including a rigid quick-connect data interface and a flexible quick-connect data interface are reserved, and the cartridge modules 1 are arranged outside the processor 2 in a predetermined manner, for example, on a specific side of the processor or around the processor 2, or even the processor 2 and the cartridge modules are respectively arranged in different rooms.
Alternatively, the shapes of the layers of the detection box modules 1 may be the same or different, for example, the bottom layer of the detection box modules 1 are arranged in a straight line, and the upper layer of the detection box modules 1 are arranged in a fold line or the like, so as to adapt to the use environment of the real-time fluorescence timing PCR instrument, and make full use of the space of the use site.
For example, the multi-layered cartridge module 1 may be stacked to form a planar wall shape, a curved wall shape, a regular triangular prism shape, a regular quadrangular prism shape, a regular pentagonal prism shape, a regular hexagonal prism shape, a cylindrical shape, or other abnormal shapes, etc.
Fig. 8 shows a schematic perspective view of the real-time fluorescent quantitative PCR instrument shown in fig. 1, in which each layer of cartridge modules 1 is arranged in a straight line shape, and the number of cartridge modules 1, the arrangement pitch, etc. of each layer are equal, thereby forming a planar wall shape, as shown in fig. 8.
Fig. 9 shows a schematic perspective view of another real-time fluorescent quantitative PCR instrument according to the present application, in which each layer of cartridge modules 1 is arranged in a square shape, and the number, arrangement pitch, etc. of cartridge modules 1 are equal, as shown in fig. 9, thereby forming a regular quadrangular tube shape.
Fig. 10 is a schematic perspective view showing another real-time fluorescent quantitative PCR instrument according to the present application, in which each layer of cartridge modules 1 is arranged in a circular shape as shown in fig. 10, and the number of cartridge modules 1, the arrangement pitch, etc. are equal to each other, thereby forming a cylindrical shape.
In this example, two adjacent layers of detection box modules 1 can be distributed in a staggered manner, alternatively, the staggered distance can be 10 mm-100 mm, and preferably 15 mm-50 mm, so that the mutual interference between the detection box modules 1 in the sample injection process is reduced, the heat dissipation space can be increased, and the stability of the detection result is improved.
It will be appreciated that the staggered distance between two adjacent layers of cartridge modules 1 may be the same or different.
In this example, the distance between two adjacent cartridge modules 1 in the same layer is at least 15mm, for example, 15mm to 30mm, so as to ensure that each of the cartridge modules 1 can sufficiently dissipate heat.
It will be appreciated that the spacing between adjacent cartridge modules 1 in the same layer may be the same or different.
Compared with the prior art, the real-time fluorescence quantitative PCR instrument provided by the application can be expanded according to the processing requirement by setting a specific arrangement mode and a data connection mode, specifically, the detection box modules in the real-time fluorescence quantitative PCR instrument provided by the application are arranged in multiple layers, and the number of the detection box modules can be specifically set according to the requirement, for example, the number of the detection box modules can be 1, 96 or even more; further, the detection box module is connected with the processor through a quick-connection data interface, so that data communication is realized, and the detection box module can be easily detached, replaced and maintained.
The application has been described in detail in connection with the specific embodiments and exemplary examples thereof, but such description is not to be construed as limiting the application. It will be understood by those skilled in the art that various equivalent substitutions, modifications or improvements may be made to the technical solution of the present application and its embodiments without departing from the spirit and scope of the present application, and these fall within the scope of the present application. The scope of the application is defined by the appended claims.
Claims (7)
1. The real-time fluorescence quantitative PCR instrument is characterized by comprising a detection box module (1) for real-time fluorescence quantitative detection and a processor (2) for collecting and processing the fluorescence quantitative detection, wherein a total starting button (23) for starting the operation of the detection box module (1) is arranged in the processor (2), a clamping groove (25) is arranged on the processor (2), a first quick-connection data interface (3) is arranged in the clamping groove (25), a second quick-connection data interface (4) is arranged on the detection box module (1), the second quick-connection data interface (4) is matched with the first quick-connection data interface (3), the clamping groove (25) is matched with the structure of the detection box module (1), the detection box module (1) is clamped in the clamping groove (25), after the detection box module (1) is clamped in the clamping groove (25), the second quick-connection data interface (4) and the first quick-connection data interface (3) are arranged on the detection box module (1), and at least two layers (24) are arranged in a plurality of layers corresponding to the detection box modules (1), and the distance between each two layers of the detection box module (1) is controlled;
The detection box module (1) is of a hexagonal prism shape, a reaction box cover (11) for adding samples is arranged on the side face of the detection box module (1), and an indicator lamp (12) for indicating whether a reaction is started or not and a heat dissipation opening (13) for dissipating heat are further arranged on the detection box module (1).
2. The real-time fluorescent quantitative PCR instrument according to claim 1, wherein each layer of cartridge modules (1) is arranged in a straight line, a curve or a ring.
3. The real-time fluorescent quantitative PCR apparatus according to claim 1, wherein the cartridge modules (1) of each layer are arranged in the same or different shapes.
4. The real-time fluorescence quantitative PCR apparatus according to claim 1, wherein two adjacent layers of detection cartridge modules (1) are staggered.
5. The real-time fluorescence quantitative PCR instrument according to claim 1, wherein the cartridge module (1) is rigidly connected to the processor via a quick-connect data interface.
6. The real-time fluorescence quantitative PCR instrument according to claim 1, wherein the first quick-connect data interface (3) comprises a USB interface or an HDMI interface; the second quick-connect data interface (4) comprises a USB interface or an HDMI interface.
7. The real-time fluorescent quantitative PCR instrument according to claim 1, further comprising a display (5) for displaying information processed by the processor (2).
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| CN202010750074.2A CN112823890B (en) | 2020-07-30 | 2020-07-30 | Real-time fluorescence quantitative PCR instrument |
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| CN202010750074.2A CN112823890B (en) | 2020-07-30 | 2020-07-30 | Real-time fluorescence quantitative PCR instrument |
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| CN204824887U (en) * | 2015-06-12 | 2015-12-02 | 杭州安杰思生物科技有限公司 | Combination real -time fluorescence quantitative PCR appearance |
| CN111007044A (en) * | 2019-11-05 | 2020-04-14 | 广州迪澳生物科技有限公司 | Optical fiber module for fluorescence detection and fluorescence detector |
| CN212663607U (en) * | 2020-07-30 | 2021-03-09 | 北京金诺美生物技术有限公司 | Real-time fluorescence quantitative PCR instrument |
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| US7767439B2 (en) * | 2003-12-10 | 2010-08-03 | Samsung Electronics Co., Ltd. | Real-time PCR monitoring apparatus and method |
| US7507575B2 (en) * | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
| CN101539778B (en) * | 2009-04-30 | 2010-11-10 | 青岛理工大学 | General basic control platform of PCR appearance |
| CN205329008U (en) * | 2015-12-31 | 2016-06-22 | 苏州百源基因技术有限公司 | Real -time fluorescence quantitative PCR appearance |
| CN208200964U (en) * | 2018-04-02 | 2018-12-07 | 长沙医学院 | A kind of microbial detection reagent kit |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204824887U (en) * | 2015-06-12 | 2015-12-02 | 杭州安杰思生物科技有限公司 | Combination real -time fluorescence quantitative PCR appearance |
| CN111007044A (en) * | 2019-11-05 | 2020-04-14 | 广州迪澳生物科技有限公司 | Optical fiber module for fluorescence detection and fluorescence detector |
| CN212663607U (en) * | 2020-07-30 | 2021-03-09 | 北京金诺美生物技术有限公司 | Real-time fluorescence quantitative PCR instrument |
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