CN112753706A - Pyraclostrobin and cyazofamid suspending agent and preparation method thereof - Google Patents
Pyraclostrobin and cyazofamid suspending agent and preparation method thereof Download PDFInfo
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- CN112753706A CN112753706A CN202011640881.5A CN202011640881A CN112753706A CN 112753706 A CN112753706 A CN 112753706A CN 202011640881 A CN202011640881 A CN 202011640881A CN 112753706 A CN112753706 A CN 112753706A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
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Abstract
The invention relates to the technical field of pesticide production, in particular to a suspending agent containing pyraclostrobin and cyazofamid and a preparation method thereof. The suspending agent containing the pyraclostrobin and the cyazofamid comprises 10-25% of the pyraclostrobin, 5-12.5% of the cyazofamid, 3-12% of a dispersing agent, 1-5% of a wetting agent, 1-5% of biological fermentation type microcrystalline cellulose, 0.5-2% of a thickening agent, 3-5% of an antifreezing agent, 0.3-1.2% of a defoaming agent and deionized water which are complemented to 100%. The suspending agent containing the pyraclostrobin and the cyazofamid is simple in preparation method and environment-friendly in used materials, the prepared suspending agent compounded by the pyraclostrobin and the cyazofamid is stable in storage particle size, the suspension rate of each component is over 96%, and the problems that the pyraclostrobin and the cyazofamid are subjected to hot melting crystallization separation, coalescence, creaming and the like in the storage process are thoroughly solved. The suspending agent prepared by the invention has excellent product performance, is beneficial to long-term storage, popularization and application of the product, and has very high social value.
Description
Technical Field
The invention relates to the technical field of pesticide production, and particularly relates to a suspending agent containing pyraclostrobin and cyazofamid and a preparation method thereof.
Background
Pyraclostrobin (pyraclosterobin), chemical name is N- {2- [1- (4-chlorophenyl) -1H-pyrazol-3-yloxymethyl ] phenyl } (N-methoxy) carbamate. Pyraclostrobin is a broad-spectrum methoxy carbamate bactericide, can inhibit mitochondrial respiration of pathogenic bacteria, and has protection, treatment and leaf conduction effects. Pyraclostrobin can prevent and kill various diseases caused by fungi, has a broad bactericidal spectrum, and is effective on various diseases of various crops including wheat, grapes, bananas, vegetables and the like. The pyraclostrobin pure product is white to light beige tasteless crystal, and the melting point is 63.7-65.2 ℃. The pyraclostrobin original drug disclosed at present has various crystal forms, and the melting point span of the pyraclostrobin original drug is large and is 44-67 ℃.
Cyazofamid (Cyazofamid), chemical name 4-chloro-2-cyano-N, N-dimethyl-5-p-tolylimidazole-1-sulfonamide. Cyazofamid is a novel low-toxicity bactericide, has good protective activity and certain systemic therapeutic activity, long lasting effect and safe use, and belongs to a mitochondrial respiration inhibitor. Cyazofamid has effect on all growth stages of oomycetes, is mainly used for preventing and treating oomycete diseases, and can be applied to various crops such as potatoes, grapes, Chinese cabbages and the like.
After the pyraclostrobin is compounded with the cyazofamid, the melting point is further reduced, the pyraclostrobin is subjected to hot melt crystallization separation, coalescence, creaming and the like during storage, and the qualified compound suspending agent cannot be prepared.
Disclosure of Invention
Based on the problems in the prior art, the invention provides the suspending agent containing the pyraclostrobin and the cyazofamid and the preparation method thereof, so that the problems of hot melt crystallization separation, coalescence, creaming and the like of the compounded pyraclostrobin and the cyazofamid in the storage process are solved, and the prepared suspending agent of the pyraclostrobin has stable performance and is beneficial to long-term storage.
In order to achieve the purpose, the invention adopts the following technical scheme:
a suspending agent containing pyraclostrobin and cyazofamid comprises the following components in percentage by mass: 10-25% of pyraclostrobin, 5-12.5% of cyazofamid, 3-12% of dispersant, 1-5% of wetting agent, 1-5% of biological fermentation type microcrystalline cellulose, 0.5-2% of thickening agent, 3-5% of antifreezing agent, 0.3-1.2% of defoaming agent and deionized water which are complemented to 100%.
The pyraclostrobin has a lower melting point, and after the pyraclostrobin is compounded with cyazofamid, the melting point is further reduced, so that the pyraclostrobin is separated out by hot melt crystallization during storage, and a qualified compound suspending agent cannot be prepared. In the research process, the invention unexpectedly discovers that the problem of instability of the compound preparation of the pyraclostrobin and the cyazofamid can be thoroughly solved by utilizing the unique and stable three-dimensional (3D) structure of the biological fermentation type microcrystalline cellulose after the biological fermentation type microcrystalline cellulose with a special structure is added into the compound preparation of the pyraclostrobin and the cyazofamid.
Preferably, the dispersing agent is formed by mixing a methoxy acrylate graft copolymer, polycarboxylate and tristyryl polyoxyethylene ether phosphate.
Preferably, the wetting agent is composed of a mixture of EO/PO block copolymer and alkyl alcohol polyoxyethylene ether.
Preferably, the thickener consists of a mixture of magnesium aluminum silicate and xanthan gum.
Preferably, the anti-freeze agent is propylene glycol.
Preferably, the defoaming agent is formed by mixing isooctyl alcohol and an organic silicon defoaming agent.
Further preferably, the suspending agent comprises the following components in percentage by mass: 10-15% of pyraclostrobin, 5-7.5% of cyazofamid, 4-6% of dispersant, 1-3% of wetting agent, 3-5% of biological fermentation type microcrystalline cellulose, 1-2% of thickening agent, 3-5% of antifreezing agent and 0.3-1.2% of defoaming agent, and the balance of deionized water is added to 100%.
Further preferably, the suspending agent comprises the following components in percentage by mass: 20-25% of pyraclostrobin, 10-12.5% of cyazofamid, 5-8% of dispersant, 2.5-5% of wetting agent, 3-5% of biological fermentation microcrystalline cellulose, 0.5-1.5% of thickening agent, 3-5% of antifreezing agent, 0.3-1.2% of defoaming agent and deionized water for supplementing to 100%.
Further preferably, the defoaming agent is prepared from isooctyl alcohol and an organic silicon defoaming agent in a mass ratio of 1: 4, mixing the components.
Further preferably, the bio-fermented microcrystalline cellulose is BacFiber microfiber of alpha biotechnology research institute, ltd.
The biological fermentation type microcrystalline cellulose is a biological fermentation product, and is green and environment-friendly; can be directly added into the formula without dissolving or activating in advance; high available specific surface area of 100-800m with functional hydroxyl groups2The bio-fermentation type microcrystalline cellulose has a remarkable stability due to its unique structure, and is purer than natural cellulose, and can form a 'nano-scale' structure invisible to the naked eye.
The biological fermentation type microcrystalline cellulose has excellent water retention performance and a suspension floating function by virtue of a stable nano-scale three-dimensional network structure, and can lock fine particles in active ingredients of a suspension in a 3D (three-dimensional) network, so that the suspended particles are protected from being influenced by storage conditions. Compared with the traditional hydrolyzed cellulose, the structure is more stable, and the suspending ability and the anti-crystallization ability are stronger. In addition, the biological fermentation type microcrystalline cellulose has good compatibility with the dispersing agent, and is combined with the dispersing agent to form a stable layer to inhibit suspended particles from separating from a net structure, so that the stabilizing effect is enhanced.
The invention also provides a preparation method of the suspending agent containing pyraclostrobin and cyazofamid, which comprises the following steps:
the method comprises the following steps: uniformly mixing the dispersing agent with a wetting agent, biological fermentation microcrystalline cellulose, a defoaming agent and deionized water, and carrying out high-speed shearing to obtain a feed liquid A after the high-speed shearing is finished;
step two: placing the pyraclostrobin and the cyazofamid in the feed liquid A, uniformly dispersing, controlling the temperature of the material at 0-30 ℃ for sanding, and obtaining a feed liquid B after sanding;
step three: and (3) putting the thickening agent and the antifreezing agent into the material liquid B in proportion, and uniformly dispersing to obtain the suspending agent.
Preferably, in the step one, the high-speed shearing speed is 800-2000 rpm, and the time is 30-60 minutes.
Preferably, in the second step, a high-speed shearing machine is used for dispersing, a sand mill is used for sanding, zirconia beads with the particle size of 0.6-0.8mm are filled in the sand mill, and sanding is stopped when the particle size D90 of the material reaches 0.05-5 um.
The preparation method of the suspending agent is simple, the used materials are environment-friendly, the prepared pyraclostrobin and cyazofamid compound suspending agent has stable storage particle size, the suspension rate of each component is more than 96 percent and can reach more than 99 percent at most, the problems of hot melting crystallization separation, coalescence, creaming and the like of the pyraclostrobin and cyazofamid compound in the storage process are thoroughly solved, the product performance is excellent, the long-term storage, popularization and application of the product are facilitated, and the high social value is achieved.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The biofermented microcrystalline cellulose used in each example is preferably Bacfiber microfiber of alpha Biotechnology research institute (Guangzhou) Inc., and the other additives are conventional in the art unless otherwise specified.
Example 1
The embodiment provides a 15% pyraclostrobin cyazofamid suspending agent, which consists of the following components in percentage by mass: 10% of pyraclostrobin and 5% of cyazofamid; dispersing agent: 2.5% of methoxy acrylate graft copolymer, 1% of polycarboxylate and 1% of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 1% of EO/PO block copolymer and 0.5% of alkyl alcohol polyoxyethylene ether; 3% of biological fermentation type microcrystalline cellulose; thickening agent: 0.2% of xanthan gum and 1% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 70.3% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 12000 rpm for 40 minutes, controlling the sanding temperature at 30 ℃, grinding the materials by a sand mill until the particle size D90 reaches 4.5um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 15% pyraclostrobin cyazofamid suspending agent.
Example 2
The embodiment provides a 33% pyraclostrobin cyazofamid suspending agent, which consists of the following components in percentage by mass: pyraclostrobin 22%, cyazofamid 11%; dispersing agent: 3.5 percent of methoxy acrylate graft copolymer, 2 percent of polycarboxylate, 2.5 percent of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 2% of EO/PO block copolymer and 0.5% of alkyl alcohol polyoxyethylene ether; 4% of biological fermentation type microcrystalline cellulose; thickening agent: 0.1% of xanthan gum and 0.5% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.2% and organic silicon defoamer 0.8%; 46.9 percent of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 13000 rpm for 30 minutes, controlling the sanding temperature at 20 ℃, grinding the materials by a sand mill until the particle size D90 reaches 4um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 33% pyraclostrobin cyazofamid suspending agent.
Example 3
The embodiment provides a 30% pyraclostrobin cyazofamid suspending agent, which consists of the following components in percentage by mass: 20% of pyraclostrobin and 10% of cyazofamid; dispersing agent: 3% of methoxy acrylate graft copolymer, 2% of polycarboxylate and 2% of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 2% of EO/PO block copolymer and 1% of alkyl alcohol polyoxyethylene ether; 3% of biological fermentation type microcrystalline cellulose; thickening agent: 0.18% of xanthan gum and 0.82% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 51.5% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 14000 r/min for 20 minutes, controlling the sanding temperature at 10 ℃, grinding the materials by a sand mill until the particle size D90 reaches 3.5um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 30% pyraclostrobin cyazofamid suspending agent.
Example 4
The embodiment provides a 22.5% pyraclostrobin cyazofamid suspending agent, which comprises the following components in percentage by mass: pyraclostrobin 15%, cyazofamid 7.5%; dispersing agent: 2.5 percent of methoxyl acrylate graft copolymer, 1.5 percent of polycarboxylate and 1 percent of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 1.5 percent of EO/PO block copolymer and 0.5 percent of alkyl alcohol polyoxyethylene ether; 3.5 percent of biological fermentation type microcrystalline cellulose; thickening agent: 0.2% of xanthan gum and 0.8% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 61.5% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 15000 r/min for 10 min, controlling the sanding temperature at 5 ℃, grinding the materials by a sand mill until the particle size D90 reaches 3um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 22.5% pyraclostrobin cyazofamid suspending agent.
Example 5
The embodiment provides an 18% pyraclostrobin cyazofamid suspending agent, which consists of the following components in percentage by mass: pyraclostrobin 12%, cyazofamid 6%; dispersing agent: 2.5 percent of methoxy acrylate graft copolymer, 1 percent of polycarboxylate and 2 percent of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 1% of EO/PO block copolymer and 1% of alkyl alcohol polyoxyethylene ether; 4% of biological fermentation type microcrystalline cellulose; thickening agent: 0.2% of xanthan gum and 1% of magnesium aluminum silicate; an antifreezing agent: 5% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 63.8% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 14500 r/min for 25 min, controlling the sanding temperature at 15 ℃, grinding the materials by a sand mill until the particle size D90 reaches 2um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 18% pyraclostrobin cyazofamid suspending agent.
Example 6
The embodiment provides a 37.5% pyraclostrobin cyazofamid suspending agent, which comprises the following components in percentage by mass: 25% of pyraclostrobin and 12.5% of cyazofamid; dispersing agent: 3.5 percent of methoxy acrylate graft copolymer, 2 percent of polycarboxylate, 2.5 percent of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 2.5 percent of EO/PO block copolymer and 0.5 percent of alkyl alcohol polyoxyethylene ether; 4.5 percent of biological fermentation type microcrystalline cellulose; thickening agent: 0.1% of xanthan gum and 0.4% of magnesium aluminum silicate; an antifreezing agent: 3% of propylene glycol; defoaming agent: isooctanol 0.15% and organic silicon defoamer 0.6%; and 42.75% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding the original medicines pyraclostrobin and cyazofamid into the mixed solution, shearing at 13500 rpm for 45 minutes at a high speed, controlling the sanding temperature at 20 ℃, grinding the materials by a sand mill until the particle size D90 reaches 1um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 37.5% pyraclostrobin cyazofamid suspending agent.
Comparative example 1
The embodiment provides a 30% pyraclostrobin cyazofamid suspending agent without adding biological fermentation type microcrystalline cellulose, which comprises the following components in percentage by mass: 20% of pyraclostrobin and 10% of cyazofamid; dispersing agent: 3% of methoxy acrylate graft copolymer, 2% of polycarboxylate and 2% of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 2% of EO/PO block copolymer and 1% of alkyl alcohol polyoxyethylene ether; thickening agent: 0.18% of xanthan gum and 0.82% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 54.5% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent and a defoaming agent according to mass percent, uniformly mixing, adding raw pesticide pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 14000 r/min for 20 min, controlling the sanding temperature at 10 ℃, grinding the materials by a sand mill until the particle size D90 reaches 3.5um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 30% pyraclostrobin cyazofamid suspending agent without adding biological fermentation type microcrystalline cellulose.
Comparative example 2
The embodiment provides a 30% pyraclostrobin cyazofamid suspending agent added with traditional hydrolyzed cellulose, which comprises the following components in percentage by mass: 20% of pyraclostrobin and 10% of cyazofamid; dispersing agent: 3% of methoxy acrylate graft copolymer, 2% of polycarboxylate and 2% of triphenyl vinyl polyoxyethylene ether phosphate; wetting agent: 2% of EO/PO block copolymer and 1% of alkyl alcohol polyoxyethylene ether; traditional hydrolyzed cellulose 3%; thickening agent: 0.18% of xanthan gum and 0.82% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 51.5% of deionized water.
The preparation method comprises the following steps:
adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, traditional hydrolyzed cellulose and a defoaming agent according to mass percent, uniformly mixing, adding raw pesticide pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 14000 r/min for 20 min, controlling the sanding temperature at 10 ℃, grinding the material by a sand mill until the particle size D90 reaches 3.5um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 30% pyraclostrobin cyazofamid suspending agent added with the traditional hydrolyzed cellulose.
Comparative example 3
The embodiment provides a 30% pyraclostrobin cyazofamid suspending agent composed of other additives, which is composed of the following components in percentage by mass: 20% of pyraclostrobin and 10% of cyazofamid; dispersing agent: 3% of polycarboxylate, 2% of sodium lignosulfonate and 2% of alkylphenol polyoxyethylene ether; wetting agent: 2% of EO/PO block copolymer and 1% of alkyl alcohol polyoxyethylene ether; 3% of biological fermentation type microcrystalline cellulose; thickening agent: 0.18% of xanthan gum and 0.82% of magnesium aluminum silicate; an antifreezing agent: 4% of propylene glycol; defoaming agent: isooctanol 0.1% and organic silicon defoamer 0.4%; and 51.5% of deionized water.
Adding deionized water into a reaction kettle, sequentially adding a dispersing agent, a wetting agent, biological fermentation type microcrystalline cellulose and a defoaming agent according to mass percent, uniformly mixing, adding raw pesticide pyraclostrobin and cyazofamid into the mixed solution, carrying out high-speed shearing at 14000 r/min for 20 minutes, controlling the sanding temperature at 10 ℃, grinding the material by a sand mill until the particle size D90 reaches 3.5um, premixing an antifreezing agent and a thickening agent, adding the premixed antifreezing agent and the thickening agent into the ground suspension, and uniformly stirring to obtain the 30% pyraclostrobin cyazofamid suspending agent consisting of other auxiliary agents.
Examples of effects
Examples 1-6 and comparative examples 1-3 were subjected to performance tests, the results of which are shown in Table 1:
TABLE 1
Remarking: d90 means that 90% of the particles have a particle size of less than a certain value.
According to the data, the combination state of the biological fermentation type microcrystalline cellulose or the common cellulose and the existing auxiliary materials is obviously poor, serious storage abnormality exists, and the suspending agent containing the pyraclostrobin and the cyazofamid has the advantages of stable particle size of the stored suspended particles, high suspension rate, excellent performance and high stability of the suspension under the action of the biological fermentation type microcrystalline cellulose, the auxiliary material dispersing agent and the wetting agent.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (9)
1. A suspending agent containing pyraclostrobin and cyazofamid is characterized in that: the composite material comprises the following components in percentage by mass: 10-25% of pyraclostrobin, 5-12.5% of cyazofamid, 3-12% of dispersant, 1-5% of wetting agent, 1-5% of biological fermentation type microcrystalline cellulose, 0.5-2% of thickening agent, 3-5% of antifreezing agent, 0.3-1.2% of defoaming agent and deionized water which are complemented to 100%.
2. The pyraclostrobin-containing suspension concentrate as claimed in claim 1, wherein: the dispersing agent is formed by mixing a methoxy acrylate graft copolymer, polycarboxylate and tristyryl polyoxyethylene ether phosphate; and/or
The wetting agent is formed by mixing EO/PO block copolymer and alkyl alcohol polyoxyethylene ether; and/or
The thickening agent is formed by mixing magnesium aluminum silicate and xanthan gum; and/or
The antifreezing agent is propylene glycol; and/or
The defoaming agent is formed by mixing isooctyl alcohol and an organic silicon defoaming agent.
3. The pyraclostrobin-containing suspension concentrate as claimed in claim 1, wherein: the suspending agent comprises the following components in percentage by mass: 10-15% of pyraclostrobin, 5-7.5% of cyazofamid, 4-6% of dispersant, 1-3% of wetting agent, 3-5% of biological fermentation type microcrystalline cellulose, 1-2% of thickening agent, 3-5% of antifreezing agent and 0.3-1.2% of defoaming agent, and the balance of deionized water is added to 100%.
4. The pyraclostrobin-containing suspension concentrate as claimed in claim 1, wherein: the suspending agent comprises the following components in percentage by mass: 20-25% of pyraclostrobin, 10-12.5% of cyazofamid, 5-8% of dispersant, 2.5-5% of wetting agent, 3-5% of biological fermentation microcrystalline cellulose, 0.5-1.5% of thickening agent, 3-5% of antifreezing agent, 0.3-1.2% of defoaming agent and deionized water for supplementing to 100%.
5. The suspending agent containing pyraclostrobin and cyazofamid as claimed in any one of claims 1 to 4, wherein: the defoaming agent is prepared from isooctyl alcohol and an organic silicon defoaming agent according to the mass ratio of 1: 4, mixing the components.
6. The suspending agent containing pyraclostrobin and cyazofamid as claimed in any one of claims 1 to 4, wherein: the biological fermentation type microcrystalline cellulose is BacFiber microfiber of AlphaBiotechnology research institute Co.
7. The preparation method of the pyraclostrobin-containing suspending agent and cyazofamid as claimed in any one of claims 1 to 6, characterized by comprising the steps of:
the method comprises the following steps: uniformly mixing the dispersing agent with a wetting agent, biological fermentation microcrystalline cellulose, a defoaming agent and deionized water, and carrying out high-speed shearing to obtain a feed liquid A after the high-speed shearing is finished;
step two: placing the pyraclostrobin and the cyazofamid in the feed liquid A, uniformly dispersing, controlling the temperature of the material at 0-30 ℃ for sanding, and obtaining a feed liquid B after sanding;
step three: and (3) putting the thickening agent and the antifreezing agent into the material liquid B in proportion, and uniformly dispersing to obtain the suspending agent.
8. The preparation method of the pyraclostrobin-containing suspension concentrate as claimed in claim 7, wherein the amount of the suspending agent is as follows: in the first step, the high-speed shearing speed is 800-2000 r/min, and the time is 30-60 min.
9. The preparation method of the pyraclostrobin-containing suspension concentrate as claimed in claim 7, wherein the amount of the suspending agent is as follows: and in the second step, dispersing by using a high-speed shearing machine, sanding by using a sand mill, filling zirconia beads with the particle size of 0.6-0.8mm in the sand mill, and sanding until the particle size D90 of the material reaches 0.05-5 um.
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| CN103857739A (en) * | 2011-10-05 | 2014-06-11 | Fmc有限公司 | Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses |
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| WO2010046387A2 (en) * | 2008-10-21 | 2010-04-29 | Basf Se | Use of a respiration complex iii inhibitor on cultivated plants |
| CN103857739A (en) * | 2011-10-05 | 2014-06-11 | Fmc有限公司 | Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses |
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