CN112691279A

CN112691279A - Catheter for abdominal cavity implantation type drug administration device

Info

Publication number: CN112691279A
Application number: CN202110024695.7A
Authority: CN
Inventors: 孔维维; 钱丰; 陈希明
Original assignee: Suzhou Linhwa Medical Devices Co ltd
Current assignee: Suzhou Linhwa Medical Devices Co ltd
Priority date: 2021-01-08
Filing date: 2021-01-08
Publication date: 2021-04-23

Abstract

The invention discloses a catheter for an abdominal cavity implantation type drug delivery device, which comprises a catheter body with a hollow interior, wherein a group of side holes communicated with the hollow interior of the catheter body are arranged on the wall of the catheter body close to the output end of the catheter body, are arranged at intervals and are spirally and uniformly distributed on the wall of the catheter body around the central axis of the catheter body; the projection of the side hole on the orthographic projection surface is in a water drop shape, the water drop shape setting direction of the side hole is consistent with the axial direction of the catheter body, the caliber of the side hole is gradually enlarged from the inner wall of the catheter body to the outer wall of the catheter body, and the liquid medicine in the catheter body flows out along the hole wall of the side hole and then flows spirally along the outer wall of the catheter body. The side holes which are spirally arranged are arranged on the tube wall of the output end of the catheter to assist in outputting the liquid medicine; the liquid medicine flows uniformly along the outer tube wall of the catheter after flowing out of the side hole, completely covers the outer tube wall of the catheter and avoids hurting and puncturing peripheral organs; the outside of the aperture of the side hole is big and the inside is small, thereby facilitating the outflow of the liquid medicine in the catheter and reducing the blockage.

Description

Catheter for abdominal cavity implantation type drug administration device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a catheter for an abdominal cavity implanted drug delivery device.

Background

When the abdominal tumor patient is in chemotherapy, the catheter for abdominal chemotherapy is implanted into the abdominal cavity of the patient for a long time, and chemotherapy drugs directly act on the tumor or free cancer cells and the micrometastasis focus through the catheter to achieve a better treatment purpose.

At present, the tube mouth end of the catheter for abdominal cavity chemotherapy which is clinically applied and implanted into the abdominal cavity is generally in an open type, or one or more small round hole-shaped side holes are arranged at the section close to the tube mouth. In the using process, blood often enters the lumen, coagulates in the lumen and blocks the catheter; in addition, lipid components in the abdominal cavity are complex and are mixed with a large amount of protein substances, and a simple straight opening catheter or a small round hole-shaped opening is easily covered by the substances such as lipid, fibrin, blood cells and the like in the using process, so that the catheter is blocked, and complications are caused; most of the existing conduits are made of silica gel materials, and can adsorb lipid substances, thereby further causing clogging; on the other hand, in order to ensure the supporting force and the flow rate, the thickness of the catheter made of the silica gel material is large, so that a patient has strong foreign body sensation, and peritonitis is easily caused. The general solution is to inject heparin normal saline into the catheter, and sometimes side effects are generated due to the self-reason of the patient; in addition, the common catheter only has one administration port, so that the liquid medicine is not diffused uniformly, and the whole recovery of the lesion part is not facilitated. Although the small round hole-shaped side holes are added, certain tube blocking risks can be reduced, and the uniformity of liquid medicine diffusion is improved, needle-like injection can be generated during liquid medicine infusion, so that surrounding organs are easily injured by puncture, and the injury is caused to patients.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provides a catheter for an abdominal cavity implantation type drug delivery device.

The purpose of the invention is realized by the following technical scheme:

the catheter for the abdominal cavity implantation type drug delivery device comprises a catheter body with a hollow interior, wherein a group of side holes communicated with the hollow interior of the catheter body are formed in the catheter wall of the catheter body close to the output end of the catheter body, are arranged at intervals and are spirally and uniformly distributed on the catheter wall of the catheter body around the central axis of the catheter body; the projection of the side hole on the orthographic projection surface is in a water drop shape, the water drop shape setting direction of the side hole is consistent with the axial direction of the catheter body, the caliber of the side hole is gradually enlarged from the inner wall of the catheter body to the outer wall of the catheter body, and the liquid medicine in the catheter body flows out along the hole wall of the side hole and then flows spirally along the outer wall of the catheter body.

Preferably, the side opening has first pore wall and the second pore wall of relative setting, first pore wall and second pore wall certainly the outside of pipe body is to its inside straight extension and connect, first pore wall with the outline of second pore wall is the arc, just the arc length of first pore wall is greater than the arc length of second pore wall to form the water droplet form the side opening.

Preferably, an included angle not smaller than 90 degrees is formed between the first hole wall and the second hole wall, the first hole wall extends obliquely towards the output end and is in smooth transition with the pipe wall of the catheter body, so that the liquid medicine in the catheter body flows out along the extending direction of the first hole wall.

Preferably, the second hole wall extends obliquely towards the input end of the catheter body, and an included angle between the second hole wall and the axis of the catheter body is greater than 45 °.

Preferably, the lowest point of the connection between the first hole wall and the second hole wall is a turning point of the first hole wall and the second hole wall, and a vertical distance between the turning point and the inner pipe wall of the catheter body does not exceed the radius of the inner pipe diameter of the catheter body.

Preferably, the spacing distance between every two side holes is equal.

Preferably, the catheter body is provided with a plurality of side holes.

Preferably, the aperture of the output end is gradually reduced to form a conical opening.

Preferably, the catheter is made of a polyurethane material and has an inner diameter of 8.5F.

The invention has the following beneficial effects:

1. a side hole is arranged on the tube wall of the output end of the catheter to assist in outputting the liquid medicine, so that the catheter is prevented from losing efficacy after the output end is blocked;

2. the outside of the aperture of the side hole is large and the inside is small, so that the liquid medicine in the catheter can flow out conveniently, and simultaneously, substances outside the catheter are difficult to flow into the catheter from the outside, so that the catheter is effectively prevented from being blocked;

3. the side holes are uniformly distributed on the tube wall in a spiral shape, the periphery of the catheter is covered in a 360-degree all-round manner, so that liquid medicine can uniformly flow along the outer wall of the catheter body after flowing out of the side holes under the influence of the flowing inertia of the liquid medicine, is fully contacted with a part needing medicine application, is favorable for realizing the medicine effect to the maximum degree, and is not easy to stick to the surface of an abdominal cavity, the risk of blockage of the side holes is reduced, and the safe use of the catheter is ensured;

4. the side hole is in a water-drop shape, and the first hole wall extends towards the output end, so that the liquid medicine can smoothly flow out along the first hole wall while flowing out towards the output end, the smoothness of liquid medicine output in the side hole is ensured, the liquid medicine is prevented from being jetted in a stabbing manner to cause puncture injury to the abdominal cavity, and the use safety is guaranteed;

5. the first hole wall and the second hole wall are oppositely arranged, so that the processing is convenient, the hole diameter of the side hole is enlarged, and the liquid medicine is convenient to output;

6. the medical catheter is made of polyurethane materials, the polyurethane materials have high toughness and smoothness, the adsorbability of the outer wall of the catheter to lipid substances is greatly reduced, reliable supporting force is provided for the flowing of liquid medicine, foreign body sensation of patients is reduced, and stimulation to peritoneum is reduced.

Drawings

The technical scheme of the invention is further explained by combining the accompanying drawings as follows:

FIG. 1: the structure of the embodiment of the invention is shown schematically;

FIG. 2: an enlarged view of portion a in fig. 1;

FIG. 3: the flow direction of the liquid medicine in the embodiment of the invention is shown schematically;

FIG. 4: in the embodiment of the invention, the liquid medicine flows out of the conduit and then flows to the schematic diagram.

Detailed Description

The present invention will be described in detail below with reference to specific embodiments shown in the drawings. These embodiments are not intended to limit the present invention, and structural, methodical, or functional changes that may be made by one of ordinary skill in the art in light of these embodiments are intended to be within the scope of the present invention.

In the description of the schemes, it should be noted that the terms "center", "upper", "lower", "left", "right", "front", "rear", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In the description of the embodiment, the operator is used as a reference, and the direction close to the operator is a proximal end, and the direction away from the operator is a distal end.

As shown in fig. 1 to 4, the present invention discloses a catheter for an intraperitoneal implantation type drug delivery device, which comprises a catheter body 1 with a hollow interior, wherein a group of side holes 3 communicated with the hollow interior of the catheter body 1 are arranged on the wall of the catheter body 1 close to the output end 2, the side holes 3 are arranged at intervals, and are spirally and uniformly distributed on the wall of the catheter body 1 around the central axis of the catheter body 1; the projection of the side hole 3 on the orthographic projection surface is in a water drop shape, the water drop shape setting direction is consistent with the axial direction of the catheter body 1, the caliber of the side hole 3 is gradually enlarged from the inner wall of the catheter body 1 to the outer wall of the side hole, and the liquid medicine in the catheter body 1 flows along the hole wall of the side hole 3 and then flows along the outer wall of the catheter body 1 in a spiral mode. The side hole 3 is arranged to assist in outputting the liquid medicine, so that after the output end 2 is prevented from being blocked, the catheter body 1 fails and cannot output the liquid medicine.

As shown in fig. 1 and 4, in the present invention, the side holes 3 are uniformly distributed on the tube wall in a spiral shape, so that the discharged drug solution can cover the outer circumference of the catheter body 1 in all directions at 360 degrees, and can be uniformly discharged in the same direction as the main discharge direction, and can be sufficiently contacted with the site to be administered, which is helpful for maximizing the drug effect; the catheter body 1 is not easy to stick to the surface of the abdominal cavity, and the risk of blocking the side hole 3 is reduced. Meanwhile, due to the existence of the side hole 3, the liquid medicine can generate a small-range rotational flow when passing through the vicinity of the side hole 3, and the liquid medicine can spread and flow along the outer tube wall of the catheter body 1 under the influence of inertia after flowing out along the side hole 3, so that the damage to surrounding visceral organs is avoided, peritonitis is avoided, and the use safety of the invention is ensured.

Specifically, as shown in fig. 1 to 4, the side hole 3 has a first hole wall 4 and a second hole wall 5 which are oppositely disposed, the first hole wall 4 and the second hole wall 5 extend and connect from the outside of the catheter body 1 to the inside thereof, the outer contours of the first hole wall 4 and the second hole wall 5 are both arc-shaped, and the arc length of the first hole wall 4 is greater than that of the second hole wall 5, so as to form the water-drop-shaped side hole 3. The side hole 3 that drops form compares in circular, and it has certain guide effect to the output mode of liquid medicine, can be so that the liquid medicine that flows out flows along the extending direction of side hole 3 to avoided the liquid medicine to follow jet out in the side hole 3, avoided causing the puncture to the abdominal cavity, arouse peritonitis, ensured safe in utilization.

The first hole wall 4 extends obliquely towards the output end 2 and is in smooth transition with the tube wall of the catheter body 1, so that the first hole wall 4 is attached to the extending direction of the catheter body 1 as much as possible, and the liquid medicine in the catheter body 1 flows along the first hole wall 4 and then flows along the outer tube wall of the catheter body 1 as much as possible. The structure reduces the obstruction of the connection between the first hole wall 4 and the outer side wall of the catheter body 1 to the liquid medicine output, so that the liquid medicine in the side hole 3 smoothly flows out along the first hole wall 4 under the influence of inertia thereof, and spirally flows along the extension direction of the outer wall of the catheter body 1 along the outer tube wall of the catheter body 1.

As shown in fig. 1 and 3, an included angle not less than 90 ° is formed between the first hole wall 4 and the second hole wall 5, the second hole wall 5 extends obliquely toward the input end 6 of the catheter body 1, and the included angle between the second hole wall 5 and the axis of the catheter body 1 is greater than 45 °. Such a structure can enlarge the opening angle of the side hole 3 to improve the output efficiency of the liquid medicine. The second hole wall 5 is of a vertical structure, so that liquid medicine can flow out along the first hole wall 4, and liquid medicine spraying output is further avoided.

Further, the lowest point of the connection between the first hole wall 4 and the second hole wall 5 is a turning point 7 of the two, and the vertical distance between the turning point 7 and the inner pipe wall of the pipe body 1 does not exceed the radius of the inner pipe diameter of the pipe body 1. Such a structure effectively improves the toughness of the wall of the catheter body 1 at the position of the side hole 3, avoiding its breakage at the inflection point 7.

In the preferred embodiment, the catheter body 1 is provided with 5 side holes 3 within 10cm close to the output end 2, and the distance between every two side holes 3 is equal. The structure can further ensure the average output of the liquid medicine, adapts to the range of the part required by the liquid medicine, achieves the aim of outputting the liquid medicine in a targeted manner, avoids excessively arranging the side holes 3, outputs the liquid medicine to the part not required, and improves the accuracy of the output of the liquid medicine. Of course, in other possible embodiments, the number and distance of the side holes 3 can be adjusted according to specific situations.

As shown in fig. 3, the diameter of the output end 2 gradually decreases outward to form a conical opening. The structure facilitates the catheter body 1 to be deeply inserted into the abdominal cavity, and partial liquid medicine can be output from the side hole 3, so that the quantity of the liquid medicine reaching the output end 3 is reduced to a certain extent, the reduced opening caliber is more suitable for stable output of the liquid medicine, and the inflow of external substances can be reduced.

In the preferred embodiment, the catheter body 1 is made of a polyurethane material and has an inner diameter of 8.5F. Compared with the existing silica gel materials, the catheter body 1 has thinner tube wall and smaller outer diameter under the condition of ensuring the flow so as to reduce the foreign body sensation of a patient; and the polyurethane material can make the outer wall of the catheter body 1 smoother, so that the adsorption of lipid substances is reduced, the smooth output of liquid medicine is improved, the stimulation of the catheter body 1 to peritoneum is effectively reduced, and the generation of peritonitis is greatly reduced. Meanwhile, the polyurethane has better toughness, so that the polyurethane is not easy to break, and the use convenience and safety are further improved.

It should be understood that although the present description refers to embodiments, not every embodiment contains only a single technical solution, and such description is for clarity only, and those skilled in the art should make the description as a whole, and the technical solutions in the embodiments can also be combined appropriately to form other embodiments understood by those skilled in the art.

The above-listed detailed description is only a specific description of a possible embodiment of the present invention, and they are not intended to limit the scope of the present invention, and equivalent embodiments or modifications made without departing from the technical spirit of the present invention should be included in the scope of the present invention.

Claims

1. The catheter for the abdominal cavity implantation type drug delivery device is characterized in that: the catheter comprises a catheter body (1) with a hollow interior, wherein a group of side holes (3) communicated with the hollow interior of the catheter body are formed in the catheter wall, close to an output end (2) of the catheter body (1), the side holes (3) are arranged at intervals and are spirally and uniformly distributed on the catheter wall of the catheter body (1) around a central axis of the catheter body (1); the projection of side opening (3) on its orthographic projection face is the water droplet form, its water droplet form set up the direction with the axial direction of pipe body (1) is unanimous, just the bore of side opening (3) is enlarged gradually to its outer wall from the inner wall of pipe body (1), liquid medicine in pipe body (1) is along follow behind the pore wall outflow of side opening (3) the outer wall spiral flow of pipe body (1).

2. The catheter for the intraperitoneal implantable drug delivery device according to claim 1, wherein: side opening (3) have relative first pore wall (4) and second pore wall (5) that set up, first pore wall (4) and second pore wall (5) certainly the outside of pipe body (1) is to its inside straight extension and connect, first pore wall (4) with the outline of second pore wall (5) is the arc, just the arc length of first pore wall (4) is greater than the arc length of second pore wall (5) to form the water droplet form side opening (3).

3. The catheter for the intraperitoneal implantable drug delivery device according to claim 2, wherein: an included angle of not less than 90 degrees is formed between the first hole wall (4) and the second hole wall (5), the first hole wall (4) extends towards the output end (2) in an inclined mode, and the first hole wall and the second hole wall are in smooth transition with the pipe wall of the catheter body (1), so that liquid medicine in the catheter body (1) flows out along the extending direction of the first hole wall (4).

4. The catheter for the intraperitoneal implantable drug delivery device according to claim 3, wherein: the second hole wall (5) extends towards the input end (6) of the catheter body (1) in an inclined mode, and an included angle between the second hole wall (5) and the axis of the catheter body (1) is larger than 45 degrees.

5. The catheter for the intraperitoneal implantable drug delivery device according to claim 4, wherein: the lowest point of the connection between the first hole wall (4) and the second hole wall (5) is a turning point (7) of the first hole wall and the second hole wall, and the vertical distance between the turning point (7) and the inner pipe wall of the catheter body (1) does not exceed the radius of the inner pipe diameter of the catheter body (1).

6. The catheter for the intraperitoneal implantable drug delivery device according to claim 1, wherein: the spacing distance between each two side holes (3) is equal.

7. The catheter for the intraperitoneal implantable drug delivery device according to claim 1, wherein: the catheter body (1) is provided with 5 side holes (3).

8. The catheter for the intraperitoneal implantable drug delivery device according to claim 1, wherein: the caliber of the output end (2) is gradually reduced to form a conical opening.

9. The catheter for the intraperitoneal implantable drug delivery device according to any one of claims 1 to 8, wherein: the catheter body (1) is made of a polyurethane material and has an inner diameter of 8.5F.