CN217908578U - Drug delivery balloon catheter - Google Patents

Drug delivery balloon catheter Download PDF

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Publication number
CN217908578U
CN217908578U CN202122129297.XU CN202122129297U CN217908578U CN 217908578 U CN217908578 U CN 217908578U CN 202122129297 U CN202122129297 U CN 202122129297U CN 217908578 U CN217908578 U CN 217908578U
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China
Prior art keywords
balloon
balloon body
balloon catheter
blood vessel
tube
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CN202122129297.XU
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Chinese (zh)
Inventor
王川
张昱昕
吴占伟
霍秀丽
闵嘉诚
王书宁
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Lepu Medical Technology Beijing Co Ltd
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Lepu Medical Technology Beijing Co Ltd
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Abstract

The utility model relates to a drug delivery balloon catheter, which belongs to the field of medical instruments and comprises a balloon body and a tube seat, wherein the balloon body is provided with an attaching section which can be attached to and sealed with a blood vessel or a cavity channel after expansion, the end part of the attaching section facing to the far end of the blood vessel or the cavity channel is provided with a micropore, and the micropore is communicated with the inside of the balloon body; the tube socket is communicated with one end of the balloon body through the conveying tube, a balloon filling opening is formed in the tube socket, the conveying tube is communicated with the inside of the balloon body, and the conveying tube is used for conveying medicine. The utility model discloses a sacculus pipe of dosing can be convenient for dose to the distal end of blood vessel or chamber way to in dosing, attached section shutoff blood vessel mouth of pipe or chamber way mouth, in order to avoid the distal end injection in-process external blood to get into the distal end and influence the drug absorption, thereby guarantee the normal clear of distal end injection.

Description

Drug delivery balloon catheter
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to balloon catheter of dosing.
Background
The intimal hyperplasia restenosis following arterial intervention, whether in the area of cardiac intervention or in the area of peripheral vascular intervention, results in a sustained effect of the intervention. Therefore, the drug balloon and the drug stent can be produced at the same time, and particularly the drug balloon can not only keep the continuity of the curative effect, but also avoid the implantation of foreign matters. The action mechanism is that the medicine for inhibiting intimal hyperplasia is coated on the intima of the blood vessel through balloon dilatation, so that the blood vessel is prevented from being excessively proliferated.
At present, the existing drug balloon catheter can only coat drugs on the surface of the balloon, the balloon is sent to a lesion position through the catheter, and the drugs are released within a short time of balloon expansion, so that the effects of expanding blood vessels and treating stenosis or occlusion are achieved; in addition, the existing balloon catheter has poor administration effect aiming at the distal pathological change tissue, is easy to be diluted or eluted by circulating blood continuously entering a distal cavity, the medicine with elution loss can enter a blood vessel in the forms of a sheet, a large particle and the like to cause embolism, and treatment medicines such as paclitaxel and the like entering the blood vessel can also generate health hidden troubles to a human body due to self toxicity.
SUMMERY OF THE UTILITY MODEL
Therefore, the to-be-solved technical problem of the utility model lies in overcoming the relatively poor defect of treatment effect of the distal end medicine feeding of sacculus pipe among the prior art to provide a sacculus pipe of dosing.
In order to solve the above problem, the utility model provides a balloon catheter of dosing, include:
the balloon body is provided with an attaching section which can be attached to and plugged with a blood vessel or a cavity after expansion, and the end part of the attaching section facing the far end of the blood vessel or the cavity is provided with a micropore which is communicated with the inside of the balloon body;
the tube seat is communicated with one end of the balloon body through a conveying tube, and a balloon filling opening is formed in the tube seat;
the delivery tube is communicated with the interior of the balloon body, the interior of the delivery tube is used for delivering the medicine and is suitable for directly administering the medicine towards the far end of the blood vessel or the cavity channel through the micropores.
Further, the radial dimension of the expanded attachment section body is greater than the radial dimension of the attachment section end.
Further, the micropores are provided with a plurality of groups along the axial direction of the balloon body, and each group of micropores is provided with a plurality of micropores arranged at intervals in the circumferential direction of the balloon body.
Further, the end part of the expanded attaching section is a hemispherical surface.
Further, the diameter of the micropores is 2 to 200 μm.
Further, an inner tube penetrates through the conveying tube, and the inner tube penetrates through the balloon body and then is provided with a tip extending out of the end area.
Furthermore, the tube seat is provided with a guide wire port communicated with the inner tube.
Furthermore, the inner tube positioned in the balloon body is provided with a developing mark.
Furthermore, the two developing marks are arranged at intervals and are respectively positioned at two ends of the balloon body.
Further, the expanded diameter of the balloon body ranges between 1-30 mm.
The utility model discloses technical scheme has following advantage:
1. the utility model provides a sacculus pipe of dosing, through be equipped with the micropore on the tip towards the far end of blood vessel or chamber way at attached section, the micropore communicates with the inside of sacculus body, and can be convenient for carry out the operation of dosing to the far end of blood vessel or chamber way, in addition, when carrying out the operation of dosing, attached section is attached and can be to the distal end shutoff again on vascular wall or chamber way wall, avoid distal end injection in-process circulation blood to get into the interior dilution liquid medicine of distal end chamber way, and can guarantee the pressure of dosing under the certain circumstances of dosage, thereby be favorable to promoting distal end chamber way or the absorption utilization effect of distal end blood vessel to the medicine;
in addition, the attaching section is directly attached to the vascular wall, so that the far-end drug delivery to the blood vessel is facilitated while the vascular wall is expanded, the balloon catheter has the functions of expansion and drug delivery, the expansion pretreatment process by adopting an additional expansion balloon is avoided, and the time and the operation cost are reduced; in addition, the balloon catheter can be suitable for blood vessel cavities or non-blood vessel cavities such as arteries, veins, nasal cavities, esophagus, urethra and the like, can be operated by injecting medicines in various fluid forms such as liquid, gas or spray and the like, has wide application range, and is beneficial to being suitable for various different operation environments.
2. The utility model provides a sacculus pipe of dosing, the micropore of attaching section tip is equipped with the multiunit along the circumference of sacculus body, and every group micropore has a plurality of around the circumference interval arrangement of sacculus body, via the aforesaid setting, and can further promote the micropore to the even injection effect of blood vessel or chamber way distal end.
3. The utility model provides a sacculus pipe of dosing wears to establish the inner tube in the conveyer pipe to be equipped with the most advanced that stretches out the sacculus body other end including, and can be convenient for drive the sacculus body and pass the inner membrance gap after increasing, so that carry out process on next step.
4. The utility model provides a sacculus pipe of dosing is equipped with the development mark on the inside inner tube of sacculus body, and this development mark has two that the interval set up, and two development marks are located the both ends of sacculus body respectively, and this setting can be convenient for observe the sacculus pipe concrete position that stretches into blood vessel chamber way to according to the real-time demonstration adjustment of development mark, promote the accuracy that sacculus pipe was annotated medicine.
5. The utility model provides a sacculus pipe of dosing, attached section tip after the expansion is the hemisphere, and the operation of dosing of micropore at the maximum degree that the setting up of hemisphere also is favorable to different positions to be favorable to blood vessel or the even absorption of chamber way distal end.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural view of a drug delivery balloon catheter in an embodiment of the present invention;
FIG. 2 is a schematic structural view of a micropore attached to an end of a segment according to an embodiment of the present invention;
description of reference numerals:
1. a tip; 2. an inner tube; 3. a balloon body; 4. a delivery pipe; 5. a tube holder; 6. balloon inflation; 7. a wire guide opening; 8. micropores; 9. developing the mark; 10. and (5) attaching the sections.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Furthermore, the technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
The embodiment relates to a drug delivery balloon catheter which is suitable for expanding and delivering drugs to intima of blood vessels and specifically comprises a balloon body 3 and a tube seat 5 communicated with one end of the balloon body 3.
As shown in fig. 1, the balloon body 3 has an attaching section 10 attached to a vessel wall or a lumen wall after expansion, a micropore 8 is formed in an end portion of the attaching section 10 facing a far end of the vessel or the lumen, the micropore 8 is communicated with the inside of the balloon body 3, the tube seat 5 is communicated with one end of the balloon body 3 through the delivery tube 4, a balloon filling opening 6 for expanding the balloon body 3 is formed in the tube seat 5, the delivery tube 4 is communicated with the inside of the balloon body 3, and the inside of the delivery tube 4 is used for delivering drugs and is suitable for directly administering drugs through the micropore 8 facing the far end of the vessel or the lumen.
As a preferred embodiment, the balloon body 3 in this embodiment is a semi-compliant balloon made of a polymer elastomer, which has good elasticity and is beneficial to controlling the expansion size and size, the balloon body 3 includes a straight section horizontally disposed in the middle area, and a round end converging from the end of the straight Duan Xiang to a point of the central line, the micro-holes 8 are correspondingly disposed on the round end of the balloon body, and here, the straight sections with different lengths can be selected according to the expansion range and area of the actual requirement.
Here, preferably, the radial dimension of the expanded straight section is larger than the radial dimension of the round end, so that the straight section has the effect of plugging the wall of the blood vessel or the wall of the cavity; the end part of the attaching section 10 is arranged to be arc-shaped hemispherical, which is beneficial to the maximum administration operation of micropores at different positions, thereby being beneficial to the uniform absorption of the far end of a blood vessel or a cavity. Of course, the rounded end may be configured to be conical or otherwise shaped after expansion, as just illustrated in this embodiment.
As shown in fig. 2, the attachment section 10 on the straight section is suitable for attaching and sealing the wall of a blood vessel or a lumen after expansion, multiple groups of micropores 8 at the end part of the attachment section 10 are arranged along the axial direction of the balloon body 3, and each group of micropores 8 is provided with a plurality of micropores arranged at intervals in the circumferential direction around the balloon body 3. The number of groups of the spacing distance of the micropores 8 should be selected according to various factors such as the practical application environment and the required drug injection dosage, and the diameter of the micropores 8 is preferably between 2 and 200 μm, so that the balloon catheter can be adapted to various different injected drugs, and the application range of the balloon catheter is improved. When the balloon body 3 is inflated and expanded by the medicine, the injection medicine enters the far end of the blood vessel or the cavity from the micropores 8, so that the far-end medicine injection effect is realized. It should be noted that the expansion diameter of the balloon body 3 is preferably between 1-30mm to ensure the precision of the expansion range is controllable.
Still as shown in fig. 2, an inner tube 2 is inserted into the delivery tube 4 between the tube seat 5 and the balloon body 3 in the present embodiment, and the inner tube 2 passes through the balloon body 3 and has a tip 1 extending out of the other end of the balloon body 3. The tip 1 is arranged to facilitate the driving of the balloon body 3 to pass through the increased intimal gap, so as to facilitate the next process; here, the tube holder 5 is further provided with a guide wire port 7 communicating with the inner tube 2 for passing a guide wire into the inner tube 2, thereby facilitating the introduction of the balloon catheter to the vascular membrane region to be expanded and administered. In order to further improve the stability of the guide wire to the balloon body 3, the inner diameter of the inner tube 2 is reduced as much as possible on the premise of allowing the guide wire to move, and the guide wire opening 7 and the inner tube 2 are concentrically arranged, so that the guide wire is prevented from being influenced by the inner tube 2 to generate errors and influence the movement precision of the balloon body 3.
On the basis of the structure that the inner tube 2 is provided to facilitate threading of the guide wire, the inner tube 2 located inside the balloon body 3 in the present embodiment is further provided with two developing marks 9, preferably, the two developing marks 9 are arranged at intervals, and the two developing marks 9 are respectively located at two ends of the balloon body 3. This setting can further strengthen the location effect to sacculus body 3, is favorable to adjusting the position of sacculus body 3 on the vascular wall of treating notes medicine. Here, the development mark 9 may adopt the existing mature development technology, which is not described in detail in this embodiment.
In this embodiment, in addition to the step of injecting the drug for inhibiting hyperplasia into the balloon body 3, the balloon body 3 may be injected with physiological saline, contrast solution or a mixture thereof, so that the balloon body 3 only plays a role of expansion, and the expansion or administration operation is flexibly selected according to the use environment; meanwhile, the balloon body 3 can be suitable for various artery, vein, lacrimal passage, air passage, nasal cavity, esophagus, biliary tract, urethra and other blood vessel cavity or non-blood vessel cavity, and the injected medicine or other mixed fluid can be in various forms such as liquid, gas or spray, as long as the micro-pores 8 can be penetrated.
The utility model provides a balloon catheter of dosing sets up the attached section 10 that laminates with the vascular wall after the expansion on sacculus body 3 to through to sacculus body 3 inside transport medicine, make the medicine directly dose to blood vessel or the chamber far end from micropore 8 of attached section 10 tip, reducible medicine runs off, and be favorable to evenly dosing, promote the absorption and utilization effect of the vascular wall of treating the injection to the medicine;
in addition, the attaching section 10 is directly attached to the blood vessel wall, so that far-end administration is performed while the blood vessel wall is expanded, the balloon catheter has the functions of expansion and administration, the expansion pretreatment process by adopting an additional expansion balloon is avoided, and the time and the operation cost are reduced; in addition, the balloon catheter can adopt various medicines or mixed media, can select an expansion process or an expansion administration process according to actual conditions, can administer medicine to the same part for multiple times, can also administer medicine to multiple parts, has wide application range, and is favorable for being applied to various different operation environments.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications can be made without departing from the scope of the invention.

Claims (10)

1. A drug delivery balloon catheter, comprising:
the balloon body (3) is provided with an attaching section (10) which can be attached to and sealed with a blood vessel or a cavity after expansion, a micropore (8) is arranged at the end part of the attaching section (10) facing the far end of the blood vessel or the cavity, and the micropore (8) is communicated with the inside of the balloon body (3);
the tube seat (5) is communicated with one end of the balloon body (3) through the delivery tube (4), and a balloon filling opening (6) is formed in the tube seat (5);
the delivery pipe (4) is communicated with the interior of the balloon body (3), the interior of the delivery pipe (4) is used for delivering medicine and is suitable for directly administering medicine towards the far end of the blood vessel or the cavity channel through the micropores (8).
2. The drug delivery balloon catheter according to claim 1, wherein the expanded main body of the attachment section (10) has a radial dimension greater than a radial dimension of the end of the attachment section (10).
3. The administration balloon catheter according to claim 1, wherein the micro holes (8) are provided in plural sets in the axial direction of the balloon body (3), each set of the micro holes (8) having several ones arranged at intervals in the circumferential direction around the balloon body (3).
4. The administration balloon catheter as claimed in claim 1, wherein the expanded attachment section (10) ends in a hemispherical shape.
5. The administration balloon catheter according to claim 1, wherein the diameter of the micropores (8) is 2-200 μm.
6. The administration balloon catheter according to claim 1, characterized in that an inner tube (2) is inserted inside the delivery tube (4), said inner tube (2) having a tip (1) protruding out of the end area after passing through the balloon body (3).
7. The administration balloon catheter according to claim 6, wherein the hub (5) has a guide wire port (7) thereon communicating with the inner tube (2).
8. The drug delivery balloon catheter according to claim 6, wherein the inner tube (2) inside the balloon body (3) is provided with a visualization mark (9).
9. The administration balloon catheter according to claim 8, wherein the visualization mark (9) has two spaced visualization marks, and the two visualization marks (9) are respectively located at two ends of the balloon body (3).
10. The administration balloon catheter according to any of claims 1-9, wherein the expanded diameter of the balloon body (3) ranges between 1-30 mm.
CN202122129297.XU 2021-09-03 2021-09-03 Drug delivery balloon catheter Active CN217908578U (en)

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CN202122129297.XU CN217908578U (en) 2021-09-03 2021-09-03 Drug delivery balloon catheter

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Application Number Priority Date Filing Date Title
CN202122129297.XU CN217908578U (en) 2021-09-03 2021-09-03 Drug delivery balloon catheter

Publications (1)

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CN217908578U true CN217908578U (en) 2022-11-29

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116549066A (en) * 2023-07-05 2023-08-08 北京久事神康医疗科技有限公司 Drug delivery cutting balloon catheter
CN117101006A (en) * 2023-10-24 2023-11-24 浙江诺尔康神经电子科技股份有限公司 Artificial cochlea repeated medicine delivery device
CN117426833A (en) * 2023-12-20 2024-01-23 北京华脉泰科医疗器械股份有限公司 Thrombolysis catheter inner core and thrombolysis catheter

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116549066A (en) * 2023-07-05 2023-08-08 北京久事神康医疗科技有限公司 Drug delivery cutting balloon catheter
CN116549066B (en) * 2023-07-05 2023-09-26 北京久事神康医疗科技有限公司 Drug delivery cutting balloon catheter
CN117101006A (en) * 2023-10-24 2023-11-24 浙江诺尔康神经电子科技股份有限公司 Artificial cochlea repeated medicine delivery device
CN117101006B (en) * 2023-10-24 2024-02-02 浙江诺尔康神经电子科技股份有限公司 Artificial cochlea repeated medicine delivery device
CN117426833A (en) * 2023-12-20 2024-01-23 北京华脉泰科医疗器械股份有限公司 Thrombolysis catheter inner core and thrombolysis catheter
CN117426833B (en) * 2023-12-20 2024-03-08 北京华脉泰科医疗器械股份有限公司 Thrombolysis catheter inner core and thrombolysis catheter

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