CN114082085A - Pre-expanding type double-layer drug perfusion balloon dilatation catheter - Google Patents
Pre-expanding type double-layer drug perfusion balloon dilatation catheter Download PDFInfo
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- CN114082085A CN114082085A CN202111372846.4A CN202111372846A CN114082085A CN 114082085 A CN114082085 A CN 114082085A CN 202111372846 A CN202111372846 A CN 202111372846A CN 114082085 A CN114082085 A CN 114082085A
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1002—Balloon catheters characterised by balloon shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1018—Balloon inflating or inflation-control devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/104—Balloon catheters used for angioplasty
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22001—Angioplasty, e.g. PCTA
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
- A61M2025/1013—Multiple balloon catheters with concentrically mounted balloons, e.g. being independently inflatable
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1079—Balloon catheters with special features or adapted for special applications having radio-opaque markers in the region of the balloon
Abstract
The invention discloses a pre-expanding double-layer drug perfusion saccule dilating catheter, which is characterized in that when the pre-expanding double-layer drug perfusion saccule dilating catheter goes deep into and passes through a narrower lesion area, firstly, the catheter is inserted into the lesion part, then the pre-expansion saccule is filled to expand the lesion part, the inner saccule is used for supporting the lesion part, then medicine is filled in the whole outer layer 'chocolate' balloon, meanwhile, the breast protruding part of the outer layer balloon contacts the blood vessel wall, the friction force between the breast protruding part and the blood vessel wall is increased, the pressure is evenly released, the interlayer is minimized, the expansion is realized, because the inner balloon is fully expanded, the medicine in the outer chocolate balloon can be fully discharged from the micropores on the surface of the outer balloon to realize the full permeation of the medicine under the push force from the inner balloon and the external perfusion force, the contact area of the lesion part and the medicament is increased, and the medicament use amount and the medicament treatment efficiency are enlarged; it can also be used for perfusion of arterial blood or venous blood.
Description
Technical Field
The invention belongs to the field of medical instruments, and relates to a pre-expanded double-layer drug perfusion balloon dilatation catheter.
Background
Coronary heart disease belongs to common clinical diseases, and mainly refers to coronary artery vessels of patients with atherosclerotic lesions, thereby causing lumen stenosis and even blockage, and causing myocardial necrosis due to ischemia or anoxia; the clinical symptoms mainly comprise chest pain, usually occur during emotional agitation and heavy physical labor, and are accompanied by the phenomena of palpitation, nausea, vomiting, cyanosis, blood pressure reduction, heart failure and the like, and even cause sudden death along with the progress of diseases, thereby directly endangering the life safety of patients.
Because of the excellent efficacy and repeatable minimally invasive procedures of intraluminal treatment, intraluminal surgery has become the first choice for treating peripheral arterial disease. Percutaneous balloon dilation is one of the first techniques for endoluminal treatment. The success rate of the PTA opening blood vessel technology exceeds 95%, but the restenosis rate is as high as 20-65%.
The main structure of the current balloon dilatation catheter comprises a balloon, a catheter and a double-lumen catheter seat, and the balloon dilatation catheter is used for dilating narrow hollow organs such as blood vessels, digestive tracts and the like in a human body under the guidance of images. The drug coating balloon is formed by coating a layer of drug on the surface of a standard balloon catheter, when the balloon is sent to a diseased region, the catheter can be quickly filled, so that the drug coating on the surface of the balloon is tightly attached to the inner wall of the diseased region of a blood vessel (more drug can be directly injected, the balloon is filled, and therefore the balloon is tightly attached to the diseased region, and the drug is leaked out from the surface of the balloon), and restenosis is prevented.
Application number 202020266228.6 discloses a double-deck medicine of whole exchange type fills sacculus expansion pipe, inserts the seal wire earlier during the implementation and guides the pipe to the pathological change position and be full of the inlayer sacculus simultaneously, fills the medicine toward the inlayer sacculus through three chambeies pipe in to be full of whole outer sacculus, the medicine can receive the thrust and the external power of irritating of inlayer sacculus this moment.
When the existing drug balloon dilatation catheter is used, as only one balloon is arranged, when narrow lesions are treated, a blank pre-dilatation balloon needs to be used for pre-dilatation of the lesions, so that the drug balloon can smoothly pass through the lesions and release drugs; when the drug saccule is expanded, the drug saccule can be fully contacted with a lesion part for drug treatment; however, the narrow diseased region can not be contacted with the drug and the release amount of the drug can not meet the requirements, so that the purpose that all the diseased regions can receive the drug can not be realized, and the blood vessel can be damaged sometimes to influence the treatment effect.
Disclosure of Invention
The invention aims to solve the problems mentioned above, and the pre-expanded double-layer drug perfusion balloon dilatation catheter is suitable for various vascular occlusive diseases.
The invention adopts the following technical scheme to achieve the purpose of the invention.
A pre-expanding double-layer medicine perfusion balloon dilatation catheter is characterized in that: the inflatable balloon comprises an inner tube, a four-cavity tube, a pre-expansion balloon, an inner-layer expansion balloon, an outer-layer chocolate balloon, Mark and a tube seat; one end of the four-cavity tube is hermetically connected with a four-cavity tube seat, and the other end of the four-cavity tube is respectively connected with the pre-expansion balloon, the inner-layer expansion balloon and the outer-layer chocolate balloon; the four-cavity tube consists of a pre-expanding cavity, a filling cavity, a perfusion cavity and a wire guide cavity; the four-cavity tube seat consists of a pre-expansion tube seat, a filling tube seat, a perfusion tube seat and a guide wire tube seat; the pre-expansion saccule is connected with the pre-expansion pipe seat through the pre-expansion cavity to form a closed space; the inner-layer expansion balloon is connected with the filling tube seat through the filling cavity to form a closed space; the outer layer chocolate balloon is connected with a perfusion tube seat through a perfusion cavity to form a closed space; the pre-expansion balloon is positioned at the front ends of the inner expansion balloon and the outer chocolate balloon; the outer layer chocolate balloon used for filling medicines is sleeved outside the inner layer pre-expanded balloon; the outer surface of the outer chocolate balloon is provided with a plurality of micropores with equal intervals for filling and releasing the medicine and enabling the medicine to permeate into the body.
The outer layer chocolate balloon can be in a spiral shape, a sugarcoated haw shape or a chocolate shape.
The pre-expansion balloon inner tube is provided with two developing marks, the inner layer pre-expansion balloon inner tube is provided with two developing marks, and the two developing marks are respectively flush with the neck of the balloon.
The surface of the four-cavity tube is coated with a hydrophilic coating, so that efficient pushing and direct lesion are realized.
The chocolate balloon mastoid and the decompression groove part on the outer layer reduce the elongation rate, prevent the longitudinal stress caused by over-extension and avoid the dog bone effect; meanwhile, the pressure reduction groove can release stress, and plaque modification is facilitated; controllable and uniform expansion is realized, and the vascular injury is reduced.
The chocolate balloon mastoid and the pressure reduction groove parts on the outer layer are respectively provided with perfusion micropores, and the pore diameter of the perfusion micropores is 0.05-1.2 mm.
The surface opening of the outer layer chocolate balloon is coated with a medicine for treating lesion stenosis.
By adopting the technical scheme, the invention better realizes the aim of the invention, and the pre-expanded double-layer drug perfusion balloon dilatation catheter pre-expands the lesion part of the balloon through guide wire guide so as to realize the perfusion of the drug at 360 degrees without dead angles, realize the aim that all lesion areas can receive the drug and improve the treatment effect; when in implementation, a guide wire is inserted into the four-cavity catheter to guide and move the saccule, the pre-expansion saccule is accurately moved to a lesion part through Mark positioning, the pre-expansion saccule is inflated, pre-expanding the narrower part and reducing the target lesion stenosis at the same time, so as to realize the accurate medication of the lesion part, then the inner layer expansion saccule is moved to the position of pathological changes through the guide wire, then the inner layer saccule is filled, and then the medicine is filled into the outer layer chocolate saccule through the filling cavity, the whole outer layer chocolate balloon is filled, and at the moment, the inner layer expansion balloon is fully expanded, so that the medicine in the outer layer chocolate balloon can be simultaneously subjected to the thrust from the inner layer balloon and the external perfusion force, and then can be fully discharged from micropores on the surface of the outer layer balloon to realize full permeation of the medicine, the contact area of a lesion part and the medicine is increased, and the usage amount of the medicine is enlarged; meanwhile, the outer balloon mastoid part is in contact with the blood vessel wall, so that the friction force between the outer balloon mastoid part and the blood vessel wall is increased, and the pressure is uniformly released.
Drawings
Fig. 1 is a schematic view of the overall structure of the embodiment of the present invention.
FIG. 2 is a schematic cross-sectional view of a four-lumen catheter in accordance with an embodiment of the present invention.
In the figure:
1. pre-expanding the balloon; 2. pre-expanding the cavity; 3. an inner dilation balloon; 4. an outer "chocolate" balloon; 5. micropores; 6. filling the cavity; 7. filling the tube seat; 8. pre-expanding a tube seat; 9. a guide wire tube seat; 10. pouring a tube seat; 11. a four-lumen catheter; 12. filling the cavity; 13. mark; 14. a guidewire lumen.
It is to be understood that the appended drawings are not necessarily to scale, emphasis instead being placed upon illustrating the basic principles of the application
A suitable simplified drawing of various features of (a). The specific design features of the present application, including, for example, specific dimensions, orientations, locations, and shapes, will be determined in part by the environment in which it is used and intended to be used.
The arrangement of the pores 5 is not the one described in the figure, but other arrangements are also applicable.
Detailed Description
The invention will be clearly and completely described by the following embodiments in conjunction with the attached drawings. Those skilled in the relevant art will appreciate that the following examples are illustrative of some, but not all, of the present invention and that the present invention also provides advantages and benefits. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. This application is intended to cover not only these exemplary embodiments, but also various alternatives, modifications, equivalents and other embodiments, which may be included within the spirit and scope of the application as defined by the appended claims.
Hereinafter, embodiments will be described in more detail with reference to the accompanying drawings.
Example 1:
as shown in fig. 1, a pre-expanded double-layer drug-filled balloon dilatation catheter according to an exemplary embodiment of the present application includes: a pre-expanded balloon 1; a pre-expanded cavity 2; an inner layer expansion balloon 3; an outer layer of chocolate balloon 4; micropores 5; filling the cavity 6; filling the tube seat 7; a pre-expanded pipe base 8; a guide wire tube seat 9; a perfusion tube base 10; a four-lumen catheter 11; a perfusion chamber 12; mark 13; a guidewire lumen 14.
The pre-expanded double-layer drug perfusion balloon dilatation catheter is characterized in that a guide wire penetrates through a guide wire cavity 14 and is guided by the guide wire, so that a pre-expanded balloon passes through a diseased part, and the diseased part is accurately pre-expanded under the effect of Mark13 developing marks; then expand sacculus 3 with the inlayer through the seal wire, under Mark13 development Mark's effect, remove to the pathological change position, be full of the inlayer sacculus of having again, realize filling the medicine and full sacculus and extrude the operation of medicine through inlayer expansion sacculus 3 and outer "chocolate" sacculus this moment, still can not lead to the fact the influence to thinner pathological change position when making the medicine fill through the injection pressure of adjusting the sufficient degree of inlayer expansion sacculus 3 and outer "chocolate" sacculus, its easy operation labour saving and time saving, and more traditional pipe is more practical, can also use one piece of balloon catheter in advance less simultaneously, save patient's medical expenses, material saving cost is still environmental protection.
One end of the four-cavity tube is hermetically connected with a four-cavity tube seat, and the other end of the four-cavity tube is respectively connected with the pre-expansion balloon, the inner-layer expansion balloon and the outer-layer chocolate balloon.
As shown in fig. 1 and 2, the four-lumen catheter comprises a four-lumen catheter 11, a four-lumen tube seat and a balloon, wherein the four-lumen tube seat, namely a pre-expansion tube seat 8, a filling tube seat 7, a perfusion tube seat 10 and a guide wire tube seat 9, is hermetically connected to one end of the four-lumen catheter 11; the other end is respectively connected with a pre-expansion balloon 1, an inner layer expansion balloon 3 and an outer layer chocolate balloon 4; the guide wire cavity 14 is connected with the guide wire tube seat 9 and is only used for guiding the guide wire; one end of a pre-expansion cavity 2 in the four-cavity catheter 11 is connected with the pre-expansion balloon 1, and the other end of the pre-expansion cavity is connected with a pre-expansion tube seat 8 to form a closed space; one end of a filling cavity 6 in the four-cavity catheter 11 is connected with the inner-layer dilatation balloon 3, and the other end of the filling cavity is connected with a filling tube seat 7 to form a closed space; one end of a perfusion cavity in the four-cavity catheter 11 is connected with the outer layer chocolate balloon 4, and the other end of the perfusion cavity is connected with a perfusion tube seat 10 to form a closed space; the pre-expansion balloon and the inner layer pre-expansion balloon are both provided with Mark13 developing marks.
When a user needs to use the balloon catheter, a guide wire can be inserted into the guide wire cavity 14 through the guide wire tube seat 9 firstly, so that the guide wire can be used for guiding the catheter to deliver to a diseased region, the pre-expansion balloon 1 is accurately positioned through Mark13 and delivered to the diseased region for pre-expansion, the inner expansion balloon 3 is accurately positioned through Mark13 and delivered to the diseased region, a liquid medium is filled into the inner expansion balloon 3 through the filling tube seat 7, a medicine is filled into the outer chocolate balloon through the filling tube seat 10, and the filling pressure of the inner expansion balloon 3 and the filling tube seat 10 is adjusted to perform the operations of filling and assisting medicine infiltration and medicine leakage filling, as shown in fig. 1.
The four-cavity catheter consists of a pre-expanding cavity, a filling cavity, a perfusion cavity and a guide wire cavity, and is shown in figure 2; can be made of any one material or a mixture of several materials of polyamide or polyether amide.
The four-cavity tube seat consists of a pre-expansion tube seat, a filling tube seat, a perfusion tube seat and a guide wire tube seat; can be made by mixing polycarbonate materials.
The pre-expansion balloon is positioned at the front ends of the inner expansion balloon and the outer chocolate balloon.
The outer layer chocolate balloon used for filling medicines is sleeved outside the inner layer pre-expansion balloon.
The outer surface of the outer chocolate balloon is provided with a plurality of micropores with equal intervals for filling and releasing the medicine and enabling the medicine to permeate into the body; the distance between adjacent perfusion holes is 0.05-2.0mm, preferably 0.3-1.2mm, and more preferably 1 mm.
The outer layer chocolate balloon can be in a spiral shape, a sugarcoated haw shape or a chocolate shape.
The pre-expansion balloon inner tube is provided with two Mark development marks, the inner pre-expansion balloon inner tube is provided with two development marks, the two development marks are respectively parallel and level with the neck of the balloon, and the Mark development marks are fixed on the balloon catheter in a forging or physical bonding mode.
The surface of the four-lumen tube is coated with a hydrophilic coating, such as polyvinylpyrrolidone (PVP), Polyacrylamide (PAM), polyethylene oxide (PEO), polyvinyl alcohol (PVA).
The chocolate balloon mastoid and the decompression groove parts of the outer layer are respectively provided with perfusion micropores, and the pore diameter of the perfusion micropores is 0.05-1.2 mm, preferably 0.05-0.4mm, and further preferably 0.2 mm.
The surface opening of the outer layer chocolate balloon is coated with a medicine for treating lesion stenosis. It can be used as diagnostic medicine or therapeutic medicine, such as contrast agent, nitroglycerin, antibiotic, rapamycin, paclitaxel and its derivatives, etc.
The inner layer expansion saccule 3 and the outer layer chocolate saccule 4 can be both made of one or more mixed materials of polyamide, polyether amide, polyurethane and polytetrafluoroethylene, a gap is formed between the inner layer expansion saccule 3 and the outer layer chocolate saccule 4 for drug delivery, and meanwhile, the micropores 5 on the surface of the outer layer chocolate saccule 4 can be used for drug infusion, release and infiltration into the body.
While the foregoing embodiments have been shown and described in detail to illustrate the principles and practical applications of the balloon catheter of the present invention, it will be apparent to those skilled in the art that modifications and variations can be made thereto without departing from the spirit of the invention and the scope of the appended claims.
Claims (8)
1. A pre-expanding double-layer medicine perfusion balloon dilatation catheter is characterized in that: the inflatable balloon comprises an inner tube, a four-cavity tube, a pre-expansion balloon, an inner-layer expansion balloon, an outer-layer chocolate balloon, Mark and a tube seat; one end of the four-cavity tube is hermetically connected with a four-cavity tube seat, and the other end of the four-cavity tube is respectively connected with the pre-expansion balloon, the inner-layer expansion balloon and the outer-layer chocolate balloon; the four-cavity catheter consists of a pre-expanding cavity, a filling cavity, a perfusion cavity and a guide wire cavity; the four-cavity tube seat consists of a pre-expansion tube seat, a filling tube seat, a perfusion tube seat and a guide wire tube seat; the Mark can realize the accurate positioning of the saccule at the position of a lesion; the pre-expansion saccule is connected with the pre-expansion pipe seat through the pre-expansion cavity to form a closed space; the inner-layer expansion balloon is connected with the filling tube seat through the filling cavity to form a closed space; the outer layer chocolate balloon is connected with a perfusion tube seat through a perfusion cavity to form a closed space; the pre-expansion balloon is positioned at the front ends of the inner expansion balloon and the outer chocolate balloon; the outer layer chocolate balloon used for filling medicines is sleeved outside the inner layer pre-expanded balloon; the outer surface of the outer chocolate balloon is provided with a plurality of micropores with equal intervals for filling and releasing the medicine and enabling the medicine to permeate into the body; it can also be used for perfusion of arterial blood or venous blood.
2. The pre-expanded double-layer drug-infused balloon dilatation catheter of claim 1 wherein the outer "chocolate" balloon is shaped as a helix, a hawk, or a chocolate.
3. The pre-expanded double-layer drug-infused balloon dilatation catheter as claimed in claim 1, wherein the pre-expanded balloon inner tube is provided with two visualization marks, the inner layer pre-expanded balloon inner tube is provided with two visualization marks, and the two visualization marks are respectively flush with the neck of the balloon.
4. The pre-expanded dual drug-infused balloon dilation catheter of claim 1 wherein the surface of the four-lumen tube is coated with a hydrophilic coating.
5. The pre-expanded double-layer drug perfusion balloon dilatation catheter as claimed in claims 1 and 2, wherein the outer layer 'chocolate' balloon mastoid and the decompression groove part are respectively provided with perfusion micropores, and the pore diameter of the perfusion micropores is 0.05 to 1.2 mm.
6. The pre-expanded double-layer drug-infused balloon dilatation catheter of claim 1 wherein the outer "chocolate" balloon surface port is coated with a drug to treat stenotic lesions.
7. The pre-expanded double-layer drug-infused balloon dilatation catheter of claim 1 wherein the spacing between adjacent infusion holes is 0.05-2.0 mm.
8. The pre-expanded double-layer drug-infused balloon dilation catheter of claim 1, wherein the infusion fluid is selected from the group consisting of diagnostic drugs, therapeutic drugs, arterial blood, and venous blood.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111372846.4A CN114082085A (en) | 2021-11-19 | 2021-11-19 | Pre-expanding type double-layer drug perfusion balloon dilatation catheter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111372846.4A CN114082085A (en) | 2021-11-19 | 2021-11-19 | Pre-expanding type double-layer drug perfusion balloon dilatation catheter |
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| Publication Number | Publication Date |
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| CN114082085A true CN114082085A (en) | 2022-02-25 |
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| CN202111372846.4A Pending CN114082085A (en) | 2021-11-19 | 2021-11-19 | Pre-expanding type double-layer drug perfusion balloon dilatation catheter |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114569868A (en) * | 2022-03-01 | 2022-06-03 | 中国人民解放军西部战区总医院 | Novel double-layer medicine balloon |
| CN114712671A (en) * | 2022-04-13 | 2022-07-08 | 四川大学华西医院 | Double-layer spinous process balloon catheter carrying medicine |
| CN116510154A (en) * | 2023-04-17 | 2023-08-01 | 南京肯特复合材料股份有限公司 | Medical polytetrafluoroethylene three-lumen tube and preparation method thereof |
-
2021
- 2021-11-19 CN CN202111372846.4A patent/CN114082085A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114569868A (en) * | 2022-03-01 | 2022-06-03 | 中国人民解放军西部战区总医院 | Novel double-layer medicine balloon |
| CN114712671A (en) * | 2022-04-13 | 2022-07-08 | 四川大学华西医院 | Double-layer spinous process balloon catheter carrying medicine |
| CN114712671B (en) * | 2022-04-13 | 2023-04-07 | 四川大学华西医院 | Double-layer spinous process balloon catheter carrying medicine |
| CN116510154A (en) * | 2023-04-17 | 2023-08-01 | 南京肯特复合材料股份有限公司 | Medical polytetrafluoroethylene three-lumen tube and preparation method thereof |
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