CN112691183A - 一种苗寨古方痛症经络痛风散及其应用 - Google Patents

一种苗寨古方痛症经络痛风散及其应用 Download PDF

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CN112691183A
CN112691183A CN202110166097.3A CN202110166097A CN112691183A CN 112691183 A CN112691183 A CN 112691183A CN 202110166097 A CN202110166097 A CN 202110166097A CN 112691183 A CN112691183 A CN 112691183A
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钟东平
唐一心
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Abstract

本发明公开了一种苗寨古方痛症经络痛风散及其应用。一种苗寨古方痛症经络痛风散，包括如下组分：节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活，金银花，鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根，蜈蚣和冰片。本发明提出的苗寨古方痛症经络痛风散，可以治疗各种痛症，例如：痛风，风湿，月子病，鼻炎等，各种痛症症状可一次缓解，对皮肤无不良反应和无毒副作用。

Description

一种苗寨古方痛症经络痛风散及其应用
技术领域
本发明涉及中草药制剂技术领域，尤其涉及一种苗寨古方痛症经络痛风散及其应用。
背景技术
跌打损伤、风湿疾病是一种常见疾病，人们在生活中很容易得此病，深受病痛所折磨，现有技术治疗伤湿止痛的产品种类多，为了更好的适用各种患者的不同用药要求，其生产的剂型也很多样，目前市场上销售的酊剂、喷剂，此类药剂吸收迅速，见效也快。但其挥发性也快，难以完全吸收药的成份，持效较短，有些品牌还对皮肤有一定的不良反应或者毒副作用。
发明内容
本发明提供了一种苗寨古方痛症经络痛风散及其应用，本发明提出的苗寨古方痛症经络痛风散，可以治疗各种痛症，例如：痛风，风湿，月子病，鼻炎，头疼，感冒等，各种痛症症状可一次缓解。
本发明的目的是提出了一种苗寨古方痛症经络痛风散，包括如下组分：节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活，金银花，鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根，蜈蚣和冰片。
优选地，上述苗寨古方痛症经络痛风散，以质量份数计，包括如下组分：节节草1-5份，常春藤1-5份，鸡血藤1-5份，皂角刺1-5份，筋骨草1-5份，杜仲1-5份，桂枝1-5份，五加皮1-5份，路路通1-5份，生姜1-5份，独活1-5份，金银花1-5份，鳖甲0.5-5份，蟾酥0.5-5份，小贯众1-5份，虎杖1-5份，朱砂根1-5份，蜈蚣0.5-5份和冰片0.3-1份。
进一步优选，上述苗寨古方痛症经络痛风散，以质量份数计，包括如下组分：节节草3份，常春藤3份，鸡血藤3份，皂角刺3份，筋骨草3份，杜仲3份，桂枝3份，五加皮3份，路路通3份，生姜3份，独活3份，金银花3份，鳖甲2.5份，蟾酥2.5份，小贯众3份，虎杖3份，朱砂根3份，蜈蚣2.5份和冰片0.5份。
本发明还保护上述苗寨古方痛症经络痛风散的制备方法，包括如下步骤：将节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活和金银花混合均匀后磨粉，过80-200目筛，得到第一药粉；将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后酒制，烘干，磨粉后再放入冰片，过80-200目筛，得到第二药粉，将第一药粉和第二药粉混合均匀得到经络痛风散。
进一步优选，所述的将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后酒制的具体步骤是鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后加入一部分黄酒闷润3-4小时，然后加入另一部分黄酒炖至黄酒吸尽，所述的鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣的质量总和与黄酒的总质量比为4-6:1。
本发明还保护所述的苗寨古方痛症经络痛风散在制备用于治疗风湿性关节炎疾病的药物中的应用。
优选地，所述的药物以苗寨古方痛症经络痛风散为活性组分，加上药学常规辅料或辅助成分制备而成的皮肤外用制剂。
所述的苗寨古方痛症经络痛风散溶于黄酒中，制得古方痛症经络酒。古方痛症经络酒可治疗各种疼痛，各种风湿性关节炎，经络淤堵，顽固劳损，颈椎病，肩周炎，面部疙瘩，手脚麻木，蚊虫叮咬，跌打损伤等。
古方痛症经络酒的使用方法：各部位严重疼痛患者、先用刮痧板刮患处自发热、然后用生姜沾古方痛症经络酒反复擦拭或加以按摩30分钟左右缓解，坚持使用一段时间疗效显著。如果是严重风湿骨病疼痛行动不便患者，使用前先热敷几分钟，早、晚各一次坚持一个月左右可以行走。古方痛症经络酒男女老少皆可使用。
苗寨古方痛症经络痛风散的使用方法：先将苗寨古方痛症经络痛风散50-100克放入10～25千克水煮30分钟以上，中途不可以兑其它自来水，煮好后把药水倒桶里，把痛症的位置放桶上面，利用蒸汽熏患处，面积尽量熏宽一点，上面用厚毛巾盖好，保证不要让蒸汽散开，严重患者熏到蒸汽没有什么温度最好，然后用毛巾泡药水敷患处直到水温降低，重复敷；
或者可以用将苗寨古方痛症经络痛风散50-100克放入10～25千克水煮1小时得到药水，使用药水泡浴或者浸泡患处直至药水变凉，一天可以浸泡多次，药水原则上可以循环使用泡1-2天，使用前需要加热(每次20-30分钟)根据自己身体感觉确定时间；
或者可以将苗寨古方痛症经络酒与苗寨古方痛症经络痛风散(苗寨古方痛症经络酒与苗寨古方痛症经络痛风散的质量比为0.5-1:1)各取适量调和成糊状，然后涂抹于患处30分钟以上，时间允许可以敷几个小时，若有条件可以用灯照加热或者暖宝宝加热，严重患者一天建议一次，敷一次后即可缓解。
与现有技术相比，本发明的有益效果是：本发明提出的苗寨古方痛症经络痛风散，可以治疗各种痛症，例如：痛风，风湿，月子病，鼻炎，头疼，感冒等，各种痛症症状可一次缓解，对皮肤无不良反应和无毒副作用。
具体实施方式
以下实施例是对本发明的进一步说明，而不是对本发明的限制。除特别说明，本发明使用的设备和试剂为本技术领域常规市购产品。
实施例1
苗寨古方痛症经络痛风散，包括如下组分：节节草1克，常春藤1克，鸡血藤1克，皂角刺5克，筋骨草5克，杜仲5克，桂枝1克，五加皮1克，路路通1克，生姜5克，独活5克，金银花5克，鳖甲0.5克，蟾酥0.5克，小贯众1克，虎杖5克，朱砂根5克，蜈蚣5克和冰片1克。
苗寨古方痛症经络痛风散的制备方法，包括如下步骤：将节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活和金银花混合均匀后磨粉，过80-200目筛，得到第一药粉；将鳖甲，蟾酥，小贯众，虎杖，朱砂根和蜈蚣混合均匀后酒制，烘干，磨粉后再加入冰片，过80-100目筛，得到第二药粉，将第一药粉和第二药粉混合均匀得到经络痛风散。
酒制的具体步骤是：将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后加入一部分黄酒闷润3小时，然后加入另一部分黄酒炖至黄酒吸尽，鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣的质量总和与黄酒的总质量比为4:1。
实施例2
苗寨古方痛症经络痛风散，包括如下组分：节节草5克，常春藤5克，鸡血藤5克，皂角刺1克，筋骨草1克，杜仲1克，桂枝5克，五加皮5克，路路通5克，生姜1克，独活1克，金银花1克，鳖甲5克，蟾酥5克，小贯众5克，虎杖1克，朱砂根1克，蜈蚣0.5克和冰片0.3克。
苗寨古方痛症经络痛风散的制备方法，包括如下步骤：将节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活和金银花混合均匀后磨粉，过80-200目筛，得到第一药粉；将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后酒制，烘干，磨粉后再加入冰片，过80-200目筛，得到第二药粉，将第一药粉和第二药粉混合均匀得到经络痛风散。
酒制的具体步骤是：将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后加入一部分黄酒闷润4小时，然后加入另一部分黄酒炖至黄酒吸尽，鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣的质量总和与黄酒的总质量比为6:1。
实施例3
苗寨古方痛症经络痛风散，包括如下组分：节节草3克，常春藤3克，鸡血藤3克，皂角刺3克，筋骨草3克，杜仲3克，桂枝3克，五加皮3克，路路通3克，生姜3克，独活3克，金银花3克，鳖甲2.5克，蟾酥2.5克，小贯众3克，虎杖3克，朱砂根3克，蜈蚣2.5克和冰片0.5克。
苗寨古方痛症经络痛风散的制备方法，同实施例1，酒制的具体步骤是：将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后加入一部分黄酒闷润3.5小时，然后加入另一部分黄酒炖至黄酒吸尽，鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣的质量总和与黄酒的总质量比为5:1。
将实施例3制得苗寨古方痛症经络痛风散进行急性皮肤刺激性试验，其试验方法和试验结果如下：
依据卫生部“化妆品卫生规范”(2002)第二部分“皮肤刺激性/腐蚀性试验”中第6.3节，大耳白兔雄性4只，体重2-3Kg，按照上述“急性经皮毒性试验”的方法，取0.5g实施例3的药膏直接涂抹在动物一侧皮肤上(另一侧作为对照)，采用封闭试验，敷用时间4小时，试验结束后，用温水冲洗残留受试物，于出去受试物后1h、24h、48h和72h分别观察动物受试区和对照区的皮肤反应，最高积分均值为“0”，判断本发明提出的皮肤清毒百草组合物对动物皮肤无刺激性。
将实施例3制得苗寨古方痛症经络痛风散进行过敏试验，其试验方法和实验结果如下：
取健康小白鼠18只，体重分别为250-300g，雌雄兼用，随机分为试验组和空白对照组。取实施例3的苗寨古方痛症经络痛风散100克放入25千克水煮1小时得到药水，使用药水泡浴直至药水变凉，每天浸泡一次，每次浸泡30分钟，持续10天。试验组动物皮肤无任何反应，判断本发明提出的苗寨古方痛症经络痛风散不会对皮肤造成过敏反应。
为了验证临床疗效，实施例3制得的苗寨古方痛症经络痛风散，每个药包含有50g苗寨古方痛症经络痛风散，治疗风湿共100例临床观察，其中男性60例，女性40例，随机分为治疗组70例和对照组30例，年龄25-65岁，平均年龄45岁，病程5-24月，一般6-8月。药包的使用方法：取一袋药包(50g苗寨古方痛症经络痛风散)放入12.5千克水煮1小时得到药水，使用药水泡浴直至药水变凉，每天早晚各浸泡一次，每次浸泡30分钟，持续3-15天。经治疗15天后，治疗组60例中55例治愈，占91.67％，对照组40例中10例治愈，占25％。
实施例3制得苗寨古方痛症经络痛风散对风湿有明显的疗效。
典型病例：
病例1，吴某，男，55岁，患严重风湿骨病疼痛，行动不便，使用前热敷5分钟，早、晚各一次药浴，坚持一个星期可以行走，经回访至今未曾复发。
病例2，郭某，女，65岁，右侧上肢痛麻无力，使用前热敷5分钟，早、晚各一次药浴，坚持3天显效，10天治愈，经回访至今未曾复发。
以上仅是本发明的优选实施方式，应当指出的是，上述优选实施方式不应视为对本发明的限制，本发明的保护范围应当以权利要求所限定的范围为准。对于本技术领域的普通技术人员来说，在不脱离本发明的精神和范围内，还可以做出若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。

Claims (7)

1.一种苗寨古方痛症经络痛风散，其特征在于，包括如下组分：节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活，金银花，鳖甲，蟾酥，小贯众，虎杖，朱砂根，蜈蚣和冰片。
2.根据权利要求1所述的苗寨古方痛症经络痛风散，其特征在于，以质量份数计，包括如下组分：节节草1-5份，常春藤1-5份，鸡血藤1-5份，皂角刺1-5份，筋骨草1-5份，杜仲1-5份，桂枝1-5份，五加皮1-5份，路路通1-5份，生姜1-5份，独活1-5份，金银花1-5份，鳖甲0.5-5份，蟾酥0.5-5份，小贯众1-5份，虎杖1-5份，朱砂根1-5份，蜈蚣0.5-5份和冰片0.3-1份。
3.根据权利要求2所述的苗寨古方痛症经络痛风散，其特征在于，以质量份数计，包括如下组分：节节草3份，常春藤3份，鸡血藤3份，皂角刺3份，筋骨草3份，杜仲3份，桂枝3份，五加皮3份，路路通3份，生姜3份，独活3份，金银花3份，鳖甲2.5份，蟾酥2.5份，小贯众3份，虎杖3份，朱砂根3份，蜈蚣2.5份和冰片0.5份。
4.权利要求1所述的苗寨古方痛症经络痛风散的制备方法，其特征在于，包括如下步骤：将节节草，常春藤，鸡血藤，皂角刺，筋骨草，杜仲，桂枝，五加皮，路路通，生姜，独活和金银花混合均匀后磨粉，过80-200目筛，得到第一药粉；将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后酒制，烘干，磨粉后再放入冰片，过80-200目筛，得到第二药粉，将第一药粉和第二药粉混合均匀得到经络痛风散。
5.根据权利要求4所述的苗寨古方痛症经络痛风散的制备方法，其特征在于，所述的将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后酒制的具体步骤是：将鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣混合均匀后加入一部分黄酒闷润3-4小时，然后加入另一部分黄酒炖至黄酒吸尽，所述的鳖甲，蟾酥，小贯众，冰片，虎杖，朱砂根和蜈蚣的质量总和与黄酒的总质量比为4-6:1。
6.权利要求1所述的苗寨古方痛症经络痛风散在制备用于治疗风湿性关节炎疾病的药物中的应用。
7.根据权利要求6所述的苗寨古方痛症经络痛风散在制备用于治疗风湿性关节炎疾病的药物中的应用，其特征在于，所述的药物以经络痛风散为活性组分，加上药学常规辅料或辅助成分制备而成的皮肤外用制剂。
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