CN112641650A - Skin feeling regulator and wet tissue - Google Patents
Skin feeling regulator and wet tissue Download PDFInfo
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- CN112641650A CN112641650A CN202011595629.7A CN202011595629A CN112641650A CN 112641650 A CN112641650 A CN 112641650A CN 202011595629 A CN202011595629 A CN 202011595629A CN 112641650 A CN112641650 A CN 112641650A
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- skin
- skin feel
- wet tissue
- phenoxyethanol
- feel modifier
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- 229960005323 phenoxyethanol Drugs 0.000 claims abstract description 32
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 30
- 150000001875 compounds Chemical class 0.000 claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 239000003974 emollient agent Substances 0.000 claims abstract description 10
- 239000003755 preservative agent Substances 0.000 claims abstract description 7
- 230000002335 preservative effect Effects 0.000 claims abstract description 7
- 239000008367 deionised water Substances 0.000 claims abstract description 5
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 5
- 239000002904 solvent Substances 0.000 claims abstract description 5
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000003607 modifier Substances 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 claims description 9
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 8
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 8
- 229940041616 menthol Drugs 0.000 claims description 8
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- -1 menthane amide Chemical class 0.000 claims description 4
- 150000001413 amino acids Chemical class 0.000 claims description 3
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- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 108010020346 Polyglutamic Acid Proteins 0.000 claims description 2
- 229920000370 gamma-poly(glutamate) polymer Polymers 0.000 claims description 2
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims 1
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims 1
- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 claims 1
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 9
- 239000002826 coolant Substances 0.000 abstract description 6
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- 238000007792 addition Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 2
- 206010006784 Burning sensation Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
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- 230000035597 cooling sensation Effects 0.000 description 2
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- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 description 2
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- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 229940043375 1,5-pentanediol Drugs 0.000 description 1
- RWLALWYNXFYRGW-UHFFFAOYSA-N 2-Ethyl-1,3-hexanediol Chemical compound CCCC(O)C(CC)CO RWLALWYNXFYRGW-UHFFFAOYSA-N 0.000 description 1
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 description 1
- FINKDHKJINNQQW-UHFFFAOYSA-N 5-methyl-2-propan-2-ylcyclohexane-1-carboxamide Chemical compound CC(C)C1CCC(C)CC1C(N)=O FINKDHKJINNQQW-UHFFFAOYSA-N 0.000 description 1
- 206010007269 Carcinogenicity Diseases 0.000 description 1
- 244000248349 Citrus limon Species 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
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- 206010041349 Somnolence Diseases 0.000 description 1
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- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
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- 239000004615 ingredient Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
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- 238000000034 method Methods 0.000 description 1
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- 231100000299 mutagenicity Toxicity 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 1
- 208000007578 phototoxic dermatitis Diseases 0.000 description 1
- 231100000018 phototoxicity Toxicity 0.000 description 1
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- 238000011160 research Methods 0.000 description 1
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- 229940057910 shea butter Drugs 0.000 description 1
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- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/37—Esters of carboxylic acids
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
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Abstract
The invention discloses a skin feel regulator and a wet tissue, wherein the skin feel regulator comprises 0.1-1 wt% of a freshener compound liquid, 1-20 wt% of polyhydric alcohol, 0.1-1 wt% of a preservative, 0.1-3 wt% of a solubilizer, 2-5 wt% of an emollient and the balance of deionized water, and the wet tissue solution of the wet tissue is the skin feel regulator. The skin feeling regulator contains the freshener compound liquid compounded by the cooling agent and the phenoxyethanol, and is wiped on the skin, so that a user feels cool feeling in an array at first and then feels hot feeling, and the cool and hot skin feeling is combined, so that the effect of refreshing the mind and restoring consciousness is achieved, and the user does not feel pain by adding the skin care component.
Description
Technical Field
The invention relates to the field of chemical products, in particular to a skin feel regulator and a wet tissue.
Background
In the modern society, with the acceleration of the rhythm of life of people, the working pressure is increased, a plurality of workers need to finish work all night in overtime, and the working efficiency is easily affected by drowsiness during overtime; drivers, especially long-distance drivers, are easy to be drowsy and bring potential safety hazards due to being in a sealed single environment for a long time in the process of driving the vehicle. In order to refresh, overtime workers or drivers choose to apply a refreshing agent for refreshing, but the human body can adapt gradually after a single refreshing feeling is used for multiple times, and the refreshing effect is reduced. Therefore, it is desired to develop a skin feel modifier with multiple skin feels to solve the above problems.
The european union consumer safety science commission (SCCS) (SCCS/1575/16), 10 months in 2016, was evaluated for phenoxyethanol for acute toxicity, irritation, sensitization, phototoxicity, mutagenicity, sexual toxicity, developmental and reproductive toxicity, carcinogenicity, and the like, and underscores that phenoxyethanol is safe for use in children even at a maximum allowable concentration of 1.0%. However, phenoxyethanol is only used as a preservative so far, and no report is made on the aspect of skin feel regulation.
Disclosure of Invention
In order to solve the technical problems, the invention provides a skin feel regulator and a wet tissue, wherein the skin feel regulator contains a freshener compound liquid and is wiped on the skin, a user feels a matrix cool feel firstly and then feels a thermal sensation, and the cold and hot skin feels are combined, so that the refreshing effect is achieved, and the user does not feel pain by adding skin care ingredients.
When the addition amount of phenoxyethanol in the cosmetic exceeds a certain proportion, researches show that when the phenoxyethanol exceeds 0.4 percent, the phenoxyethanol can cause the uncomfortable reactions of skin, such as stabbing pain and burning heat, and is more obvious when the phenoxyethanol acts on sensitive skin. The action mechanism is that phenoxyethanol can activate TRPV1 channel on skin cells, thereby causing people to generate heat sensation or pain sensation.
The skin feeling regulator with multiple skin feelings and the refreshing effect is provided by compounding phenoxyethanol with other auxiliary agents within 1% of the safe additive amount of the phenoxyethanol for the skin feeling of a human body.
A skin feeling regulator comprises 0.1-1 wt% of refreshing agent compound liquid, 1-20 wt% of polyalcohol, 0.1-1 wt% of preservative, 0.1-3 wt% of solubilizer, 2-5 wt% of emollient, and the balance deionized water.
Preferably, the compound liquid of the cooling agent is at least one of menthol, menthyl lactate and menthane amide and phenoxyethanol, and the weight ratio of the compound liquid of the cooling agent to the phenoxyethanol is 1: 4-1: 5 proportion.
Preferably, the compound liquid of the cooling agent is a compound of menthol and menthyl lactate, and the weight ratio of the compound liquid of the cooling agent to phenoxyethanol is 1: 4-1: 5 proportion.
Preferably, the polyhydric alcohol is at least one of propylene glycol, butylene glycol, hexylene glycol, pentylene glycol, octylene glycol, sorbitol, and glycerin.
Preferably, the emollient comprises at least one of oat glucan, amino acid surfactant, aloe moisturizer, and sodium polyglutamate.
Preferably, the preservative comprises caprylhydroxamic acid and ethylhexyl glycerin.
Preferably, the solubilizer is hydrogenated castor oil and derivatives thereof.
Preferably, the skin feel modifier comprises 0.1-0.2% of a flavoring agent, which may assist in providing a refreshing or soothing effect through taste.
A wet tissue comprises a wet tissue base cloth and a wet tissue solution attached to the wet tissue base cloth, wherein the wet tissue solution comprises the skin-feel conditioning agent.
The skin feel modifier can also be used in daily chemicals.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a skin feel regulator with cool feel and hot feel, multiple skin feels can achieve the effect of refreshing, and the skin feel regulator is particularly suitable for long-distance drivers and people working overnight.
2 the phenoxyethanol in the existing product is used as a simple preservative, and the thermal sensation generated when the addition amount exceeds 0.4 percent is considered as an irritation phenomenon, so that the phenomenon is eliminated by adding various auxiliary agents; the invention overcomes the technical prejudice, utilizes the thermal sensation characteristic generated by phenoxyethanol to be added as a regulator with multiple skin feelings, and the generated thermal sensation is combined with the cooling sensation generated by cooling agents such as menthol, menthyl lactate, menthane carboxamide and the like, so that the product has better refreshing effect.
3 in order to avoid the stimulation, the invention adds a plurality of emollients, so that the product has the refreshing function of cold and hot skin feeling and avoids the stimulation.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
A skin feel modifier is prepared from menthol and menthyl lactate composition and phenoxyethanol by mixing the following raw materials in a ratio of 1: 5, 0.8 percent of freshener compound liquid; 10% of propylene glycol and glycerin composition, 0.4% of caprylyl hydroximic acid, 1.0% of hydrogenated castor oil and derivatives thereof, 3% of oat glucan and aloe humectant composition and the balance of deionized water.
In this embodiment, the composition of menthol and menthyl lactate can provide a cooling sensation after the user applies the composition, while the phenoxyethanol can provide a warming sensation. When a user is tired, the product is sprayed on the surface of the skin in a proper amount, the cool feeling can be generated firstly, and then the thermal feeling is generated, and the multiple feelings can play the roles of refreshing and refreshing.
Example 2
A skin feel modifier is prepared from menthol and menthyl lactate composition and phenoxyethanol by mixing the following raw materials in a ratio of 1: 4, 0.5 percent of freshener compound liquid prepared according to the proportion; 6% of suberic alcohol and glycerin composition, 0.5% of caprylyl hydroximic acid, 0.8% of hydrogenated castor oil and derivatives thereof, 5% of amino acid surfactant, 0.1% of oat glucan and aloe humectant composition, and the balance of deionized water.
Compared with the embodiment 1, the content of the freshener compound liquid is reduced, the content of phenoxyethanol is correspondingly reduced, and due to the fact that people with different physiques are different in sensitivity to phenoxyethanol when using the freshener compound liquid, when the general phenoxyethanol is added in an amount of more than 0.4%, a user starts to generate obvious burning sensation, therefore, the embodiment mainly aims at people who are sensitive to phenoxyethanol, in addition, the content of the emollient is increased, burning sensation and pricking sensation generated by phenoxyethanol when using the freshener compound liquid can be further avoided and reduced, the user can only feel cool sensation and hot sensation, and the refreshing effect is achieved. The addition of essence such as lemon essence, rose essence, etc. can assist in providing a refreshing or soothing effect.
Example 3
In order to be convenient to carry and use, the embodiment provides the wet tissue, the wet tissue takes three layers of non-woven fabrics as the base fabric of the wet tissue,
the skin-feel modifier of example 1 or example 2 was used as a wet wipe solution, the wet wipe solution content being wt 20-50.
Because of different heat sensation degrees of phenoxyethanol, the proportion of phenoxyethanol in the freshener compound liquid or the adding proportion of the freshener compound liquid can be properly increased to enhance the heat sensation degree of the phenoxyethanol compound liquid, but the adding amount of the freshener compound liquid cannot exceed wt1 percent to ensure the use safety; on the contrary, the proportion of phenoxyethanol in the freshener compound liquid is reduced or the adding proportion of the freshener compound liquid is reduced, and meanwhile, the emollient can be properly added for relieving, so that the phenoxyethanol compound liquid is better suitable for people sensitive to phenoxyethanol.
This example only shows exemplary emollient components, other emollient soothing components such as shea butter, etc. may be added.
It should be noted that the illustrated embodiments of the present invention are only exemplary, and do not represent all embodiments, and the embodiments are for clearly explaining the present invention, and should not be construed as limiting the scope of the present invention, which is defined by the claims. Modifications, substitutions, or additions which may occur to those skilled in the art and which are within the teachings of the present invention may be made without departing from the scope of the invention.
Claims (9)
1. A skin feel modifier characterized by: comprises 0.1-1% of freshener compound liquid, 1-20% of polyalcohol, 0.1-1% of preservative, 0.1-3% of solubilizer, 2-5% of emollient and the balance of deionized water.
2. The skin feel modifier of claim 1, wherein: the compound liquid of the freshener is at least one of menthol, menthyl lactate and menthane amide and phenoxyethanol, wherein the weight ratio of the compound liquid to the menthyl lactate to the menthyl amide is 1: 4-1: 5 proportion.
3. The skin feel modifier of claim 2, wherein: the compound liquid of the freshener is a compound of menthol and menthyl lactate, and is mixed with phenoxyethanol according to the weight ratio of 1: 4-1: 5 proportion.
4. The skin feel modifier of claim 3, wherein: the polyalcohol is at least one of propylene glycol, butanediol, hexanediol, pentanediol, octanediol, sorbitol and glycerol.
5. The skin feel modifier of claim 4, wherein: the emollient comprises at least one of oat glucan, amino acid surfactant, aloe humectant and sodium polyglutamate.
6. The skin feel modifier of claim 5, wherein: the preservative comprises caprylhydroxamic acid and ethylhexyl glycerol.
7. The skin feel modifier of claim 6, wherein: the solubilizer is hydrogenated castor oil and derivatives thereof.
8. A skin feel modifier according to any one of claims 1 to 7 wherein: the skin feeling regulator also comprises 0.1-0.2% by weight of essence.
9. The utility model provides a wet tissue, includes wet tissue base cloth and attaches to wet tissue solution, its characterized in that: the wet wipe solution comprising the skin feel modifier of any one of claims 1-8.
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| CN114681361A (en) * | 2022-04-02 | 2022-07-01 | 厦门金泰生物科技有限公司 | Ice-cold compound liquid and preparation method thereof |
| CN116369489A (en) * | 2023-04-21 | 2023-07-04 | 绵阳市斯麦尔顾生物科技有限公司 | Preparation method of novel food-grade cooling agent |
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Application publication date: 20210413 |