High-low speed running-matched biological centrifugal equipment based on speed-up control
Technical Field
The invention relates to the field of biological centrifugation, in particular to a biological centrifugation device which is based on high-low speed matched operation of speed-up control.
Background
The centrifugal separator is mainly used for separating solid particles from liquid in suspension; or separating two liquids which have different densities and are not mutually soluble in the emulsion; it can also be used to remove liquid from wet solids, and when separating blood, separate different components of blood layer by centrifugation.
Based on the above findings, the present inventors found that the existing high-low speed matching operation biological centrifugal device based on speed-up control mainly has the following disadvantages, such as: because the red blood cells in the blood are damaged by high-speed centrifugation, low-speed centrifugation can be selected, and a long time is required for completing the centrifugation process when the centrifugation is performed, so that the blood is coagulated when the centrifugation is performed.
Disclosure of Invention
In view of the above problems, the present invention provides a high-low speed matching operation biological centrifugal apparatus based on speed-up control.
In order to achieve the purpose, the invention is realized by the following technical scheme: the utility model provides a high low-speed cooperation moving biological centrifugal equipment based on speed-raising control, its structure includes main part, louvre, control panel, the front end bottom of main part is equipped with the louvre, control panel sets up in the middle of the front end of main part is just, the main part includes top cap, mounting groove, rotatory piece, centrifugal device, the top cap block is in the top of main part, the mounting groove sets up the inside top in the main part, rotatory piece is installed in the bottom centre of mounting groove, centrifugal device installs in the centre of mounting groove.
Furthermore, the centrifugal device comprises a rotating seat, a charging box, a material throwing device and a centrifugal groove, the charging box is clamped in the middle of the top of the rotating seat, the upper end of the charging box is arc-shaped, the material throwing device is installed in the middle of the inside of the charging box, the centrifugal groove is formed in the inside of the charging box, and the bottom of the charging box is in a cut-open shape.
Further, get rid of the material device including getting rid of material frame, perforation, outer chute, guiding device, it is circular form to get rid of the material frame, the perforation is located the bottom centre of getting rid of the material frame, outer chute is equipped with more than six, and arranges in the terminal surface of getting rid of the material frame around, guiding device is equipped with more than six, and installs between two liang of outer chutes, outer chute and the contained angle of getting rid of between the material frame terminal surface are 30 degrees.
Further, it is characterized in that: the outflow groove includes cell body, feedstock port, guide piece, the inside of cell body is equipped with feedstock port, feedstock port's width is dwindled to the outer end by inner gradually, the guide piece is equipped with two, and the outer end in the cell body is arranged perpendicularly, the terminal surface of guide piece is for carrying out the bending from top to bottom.
Further, the guiding device includes fixed plate, collection chute, circulation groove, splitter box, guide vane, the fixed plate inlays admittedly in the middle of the bottom of guiding device is positive, the collection chute is located the front end of guiding device, circulation groove transverse installation is in the middle of the inside of guiding device is positive, and is connected with the collection chute, the splitter box is equipped with threely, and transverse arrangement is in the upper end of circulation groove, the outer end at the splitter box is installed to the guide vane, the guide vane bottom is circular-arcly, and the upper end flushes with the terminal surface of guiding device mutually.
Further, the mass flow groove is including concentrating groove, depressed groove, current collector piece, the setting of concentrated groove is at the front end that leads to the groove, the depressed groove is equipped with more than six, and transverse arrangement is at the both ends of concentrating the groove, current collector piece is equipped with two, and transverse arrangement is in the port of concentrating the groove, current collector piece is by both ends to middle slope, and the angle of slope is 15 degrees.
Further, the flow-collecting piece includes circulation hole, charge-in port, reposition of redundant personnel mouth, the circulation hole sets up in the positive centre of the inside of flow-collecting piece, charge-in port sets up the top at the circulation hole, the reposition of redundant personnel mouth is equipped with more than six, and transverse arrangement both ends about the circulation hole, contained angle between reposition of redundant personnel mouth and the circulation hole is 30 degrees.
Advantageous effects
Compared with the prior art, the invention has the following beneficial effects:
1. according to the invention, the outer flow grooves are arranged in the material throwing frame, so that red blood cells with larger mass can be separated to the outer end of the material throwing frame when blood is centrifuged, and serum with smaller mass can be retained in the material throwing frame, thereby avoiding the condition that the red blood cells and the inner part of the material throwing frame impact each other to damage the red blood cells.
2. The invention utilizes the collector plate to drive the rotating blood to enter the circulation groove to flow outwards, can accelerate the separation speed of serum and red blood cells, and avoids the coagulation of the blood in the centrifugation process.
Drawings
Fig. 1 is a schematic front view of a high-low speed operation-based bio-centrifugal apparatus based on speed-up control according to the present invention.
FIG. 2 is a schematic side view of the main body of the present invention.
FIG. 3 is a schematic cross-sectional view of the centrifuge apparatus of the present invention.
Fig. 4 is a schematic top view of the material throwing device of the present invention.
Fig. 5 is a cross-sectional view of the outer flow channel of the present invention.
Fig. 6 is a schematic cross-sectional structure view of the flow guiding device of the present invention.
Fig. 7 is a schematic cross-sectional view of a flow-through channel of the present invention.
Fig. 8 is a schematic sectional view showing the structure of a current collecting plate according to the present invention.
In the figure: the device comprises a main body 1, a heat dissipation hole 2, a control panel 3, a top cover 11, a mounting groove 12, a rotating block 13, a centrifugal device 14, a rotating seat 141, a charging box 142, a material throwing device 143, a centrifugal groove 144, a material throwing frame a1, a perforation a2, an outer flow groove a3, a flow guide device a4, a groove body a31, a feeding port a32, a material guide sheet a33, a fixing plate b1, a flow collecting groove b2, a flow channel b3, a flow dividing groove b4, a guide sheet b5, a concentration groove b21, a concave groove b22, a flow collecting sheet b23, a flow hole c1, a feeding port c2 and a flow dividing port c3.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further explained by combining the specific embodiments.
The first embodiment is as follows: referring to fig. 1-5, the embodiments of the present invention are as follows:
its structure includes main part 1, louvre 2, control panel 3, the front end bottom of main part 1 is equipped with louvre 2, control panel 3 sets up in the middle of the front end of main part 1 is just, main part 1 includes top cap 11, mounting groove 12, rotatory piece 13, centrifugal device 14, top cap 11 block is in the top of main part 1, mounting groove 12 sets up the inside top in main part 1, rotatory piece 13 is installed in the middle of the bottom of mounting groove 12 is positive, centrifugal device 14 is installed in the middle of the mounting groove 12 is positive.
The centrifugal device 14 comprises a rotating base 141, a cartridge 142, a material throwing device 143 and a centrifugal groove 144, wherein the cartridge 142 is clamped in the middle of the top of the rotating base 141, the upper end of the cartridge 142 is arc-shaped, the material throwing device 143 is installed in the middle of the inside of the cartridge 142, the centrifugal groove 144 is arranged in the cartridge 142, the bottom of the cartridge 142 is cut open, so that the rotating block 13 can penetrate through the cartridge 142, and the rotating block 13 rotates to drive blood to rotate and centrifuge.
Get rid of material device 143 is including getting rid of material frame a1, perforation a2, outer chute a3, guiding device a4, it is circular form to get rid of material frame a1, perforation a2 is located the bottom centre of getting rid of material frame a1, outer chute a3 is equipped with more than six, and encircles and arrange in the terminal surface of getting rid of material frame a1, guiding device a4 is equipped with more than six, and installs between two liang of outer chutes a3, outer chute a3 and the contained angle of getting rid of between the material frame a1 terminal surface are 30 degrees, are favorable to letting blood flow to the centrifugal bowl 144 in can following outer chute a3 in rotatory.
Outer chute a3 includes cell body a31, feedstock port a32, guide piece a33, the inside of cell body a31 is equipped with feedstock port a32, feedstock port a 32's width is dwindled to the end to the inner gradually, guide piece a33 is equipped with two, and the outer end in cell body a31 is listed up perpendicularly, guide piece a 33's terminal surface is for carrying out the bending from top to bottom, is favorable to getting rid of the outer wall of material frame a1 with the blood direction that flows out from cell body a31, reduces the impact force of separating the serum in red blood cell and the centrifuge bowl 144.
Based on the above embodiment, the specific working principle is as follows: the utilization is placed blood in centrifugal device 14's inside, recycle rotatory piece 13, rotatory drive blood rotates, thereby can let blood reach the effect of separation, and the erythrocyte in blood receives to destroy and can utilize and install the inside at centrifugal device 14 with getting rid of material device 143 in the separation, make the serum after the separation can arrange in the inside of getting rid of material frame a1, and the erythrocyte can distribute in the outer end of getting rid of material frame a1, thereby let can not let hardly to cross the cell and arrange in the inside of getting rid of material frame a1 and receive to destroy and appear impaired circumstances, set up the terminal surface of guide piece a33 into bending from top to bottom at last, can get rid of the outer wall of material frame a1 with the erythrocyte direction that flows from cell body a31, reduce the impact force of having separated serum in erythrocyte and the centrifuge bowl 144.
Example two: referring to fig. 6-8, the embodiment of the present invention is as follows:
flow guide device a4 includes fixed plate b1, mass flow groove b2, circulation groove b3, splitter box b4, guide vane b5, fixed plate b1 inlays the bottom centre at flow guide device a4, collection groove b2 is located flow guide device a 4's front end, circulation groove b3 transversely installs in flow guide device a 4's inside centre, and is connected with collection groove b2, splitter box b4 is equipped with threely, and transversely arranges in the upper end of circulation groove b3, guide vane b5 installs the outer end at splitter box b4, guide vane b5 bottom is circular-arc, and the upper end flushes mutually with flow guide device a 4's terminal surface, is favorable to leveling the blood that will follow the outflow in splitter box b4 through guide vane b5, lets blood can not receive the impact when rotatory.
Collecting tray b2 is including concentrating groove b21, undercut groove b22, current collector piece b23, it sets up the front end at circulation groove b3 to concentrate groove b21, undercut groove b22 is equipped with more than six, and transverse arrangement is at the both ends of concentrating groove b21, current collector piece b23 is equipped with two, and transverse arrangement is in the port of concentrating groove b21, current collector piece b23 is by both ends to middle slope, and the angle of slope is 15 degrees, is favorable to entering into circulation groove b3 through current collector piece b23 with rotatory blood drive and flows outward.
Collector piece b23 includes opening c1, charge-in port c2, reposition of redundant personnel mouth c3, opening c1 sets up in collector piece b 23's inside centre, charge-in port c2 sets up the top at opening c1, reposition of redundant personnel mouth c3 is equipped with more than six, and transverse arrangement both ends about opening c1, contained angle between reposition of redundant personnel mouth c3 and the opening c1 is 30 degrees, is favorable to leading blood toward in opening b 3.
Based on the above embodiment, the specific working principle is as follows: set up guide plate b5 bottom to circular-arc, and set up guide plate b5 up end to flush with guiding device a 4's terminal surface mutually, can lead the blood that flows out from splitter box b4 through guide plate b5 and level, let blood can not receive the impact in rotatory, then utilize and set up collector plate b23 to incline to the centre by both ends, and the angle of slope is 15 degrees, can drive rotatory blood through collector plate b23 and enter into and flow groove b3 in toward outer, thereby with serum and blood to the separation, utilize at last to set up the contained angle between diffluence pass c3 and circulation hole c1 to 30 degrees, can lead to blood in circulation groove b3, thereby accelerate the separating rate of serum and erythrocyte, avoid blood the condition that the coagulation appears in the centrifugal in-process.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.