CN112603985A - Pure traditional Chinese medicine transdermal liniment for treating myocardial infarction and preparation method thereof - Google Patents
Pure traditional Chinese medicine transdermal liniment for treating myocardial infarction and preparation method thereof Download PDFInfo
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Abstract
The invention provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. Relates to a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which is mainly prepared from the following raw materials in parts by weight: 15-20 parts of kudzuvine root, 10-15 parts of safflower, 12-15 parts of codonopsis pilosula, 10-15 parts of rhizoma polygonati, 12-15 parts of astragalus, 12-15 parts of red paeony root, 15-20 parts of turmeric root-tuber, 10-15 parts of salvia miltiorrhiza, 15-20 parts of ligusticum wallichii, 12-15 parts of dalbergia wood and 12-15 parts of schisandra chinensis; also relates to a preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which comprises the following steps: s1, putting radix Puerariae, flos Carthami, radix Codonopsis, rhizoma Polygonati, radix astragali, radix Paeoniae Rubra, radix Curcumae, radix Salviae Miltiorrhizae, rhizoma Chuanxiong, lignum Dalbergiae Odoriferae, and fructus Schisandrae chinensis in a stone mortar according to the weight parts, and mashing into powder; s2, soaking the mashed mixed powder in 50-100 parts by weight of 75% alcohol for 20-25 days. The pure traditional Chinese medicine transdermal liniment has the advantages of small side effect, reliable curative effect, simple and quick preparation method, and convenient and safe use as liniment.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction and a preparation method thereof.
Background
Myocardial infarction refers to myocardial infarction, and refers to a disease that coronary artery blood vessels are blocked, blood supply of heart cells is interrupted, and the heart cells are necrotic.
Some existing medicines for treating myocardial infarction are prepared by combining western medicines or a plurality of pure Chinese medicinal materials according to a certain proportion; the existing preparation method of the medicine for treating myocardial infarction comprises a plurality of processes and a plurality of steps.
In the process of implementing the embodiment, the inventor finds at least the following problems:
some of the existing medicines for treating myocardial infarction have large side effects by adopting western medicines; the other medicines are in the form of pure traditional Chinese medicine compositions, but the curative effect is not obvious; in addition, some take the form of non-liniments, which are inconvenient and relatively unsafe to use.
The existing preparation method of the medicine for treating myocardial infarction has relatively complex process and multiple steps.
Disclosure of Invention
The invention aims to provide a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, and aims to solve the technical problems of insignificant curative effect, inconvenience in use and insecurity of the existing pure traditional Chinese medicine transdermal liniment for treating myocardial infarction.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which is mainly prepared from the following raw materials in parts by weight: 15-20 parts of kudzuvine root, 10-15 parts of safflower, 12-15 parts of pilose asiabell root, 10-15 parts of rhizoma polygonati, 12-15 parts of astragalus root, 12-15 parts of red peony root, 15-20 parts of curcuma aromatica, 10-15 parts of salvia miltiorrhiza, 15-20 parts of ligusticum wallichii, 12-15 parts of dalbergia wood and 12-15 parts of schisandra chinensis.
Further, 18 parts of kudzuvine root, 13 parts of safflower, 13 parts of pilose asiabell root, 12 parts of siberian solomonseal rhizome, 13 parts of membranous milkvetch root, 13 parts of red paeony root, 18 parts of turmeric root-tuber, 13 parts of danshen root, 18 parts of szechuan lovage rhizome, 13 parts of rosewood heart wood and 13 parts of Chinese magnoliavine fruit.
The beneficial effect of this scheme does:
the embodiment provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which adopts a pure traditional Chinese medicine preparation and has small side effect; the effective raw materials and reasonable proportion are adopted, so that the treatment effect on myocardial infarction is obviously improved; the external liniment is convenient and safe to use when being used as a transdermal liniment.
The invention also aims to provide a preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which aims to solve the technical problems of relatively complex preparation process and multiple steps in the existing preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention also provides a preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which comprises the following steps:
s1, putting radix Puerariae, flos Carthami, radix Codonopsis, rhizoma Polygonati, radix astragali, radix Paeoniae Rubra, radix Curcumae, radix Salviae Miltiorrhizae, rhizoma Chuanxiong, lignum Dalbergiae Odoriferae, and fructus Schisandrae chinensis in a stone mortar according to the weight parts, and mashing into powder;
s2, soaking the mashed mixed powder in 50-100 parts by weight of alcohol for 20-25 days.
Further, the volume fraction of the alcohol is 75%.
The beneficial effect of this scheme does:
the embodiment provides a preparation method of a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which comprises the steps of grinding raw materials into powder, and soaking the powder for 20-25 days by using 75% alcohol in a reasonable ratio; grinding into powder is favorable for fully mixing the medicines, and brewing with alcohol for the above days can fully exert the drug effect and synergistic effect of the components. In addition, alcohol has the effect of sterilization and disinfection, and optionally, the concentration of alcohol in the embodiment is 75%, so that the alcohol is more suitable for human skin.
Therefore, the preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction has simple preparation process and few steps, and adopts alcohol to fully dissolve the pure traditional Chinese medicine composition, so that the drug effect is fully exerted and the treatment effect is improved.
The effects of the medicines in the invention are as follows:
kudzu root: expelling pathogenic factors from muscles and skin, bringing down fever, promoting eruption, promoting the production of body fluid, quenching thirst, invigorating yang, and relieving diarrhea.
Safflower: promoting blood circulation, dredging channels, removing blood stasis and relieving pain.
Codonopsis pilosula: invigorating spleen and replenishing qi, quenching thirst, invigorating spleen and lung, nourishing blood and promoting fluid production.
Rhizoma polygonati: tonify qi and yin, invigorate spleen, moisten lung and tonify kidney.
Astragalus root: tonify qi, strengthen superficies, expel toxin, expel pus, induce diuresis, and promote granulation.
Red peony root: clear heat and cool blood, dissipate blood stasis and alleviate pain.
Turmeric root-tuber: promoting blood circulation to arrest pain, promoting qi circulation to relieve depression, clearing away heart-fire, cooling blood, promoting bile flow, and eliminating jaundice.
Red sage root: promoting blood circulation, dispelling blood stasis, dredging meridians, relieving pain, clearing away heart-fire, relieving restlessness, cooling blood, and eliminating carbuncle.
Ligusticum wallichii: move qi and relieve depression, dispel wind-dryness and dampness, activate blood and alleviate pain.
And (3) rosewood heart wood: disperse blood clots, stop bleeding, regulate qi and alleviate pain.
Schisandra chinensis: astringe lung, nourish kidney, promote fluid production, astringe sweat and astringe essence.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments.
Thus, the following detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The invention provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which is mainly prepared from the following raw materials in parts by weight: 15 parts of kudzuvine root, 10 parts of safflower, 12 parts of pilose asiabell root, 10 parts of siberian solomonseal rhizome, 12 parts of astragalus root, 12 parts of red paeony root, 15 parts of turmeric root-tuber, 10 parts of red-rooted salvia root, 15 parts of szechuan lovage rhizome, 12 parts of rosewood heart wood and 12 parts of Chinese magnoliavine fruit.
S1, the preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction comprises the following steps:
putting the kudzuvine root, the safflower, the codonopsis pilosula, the sealwort, the astragalus root, the red paeony root, the turmeric root-tuber, the salvia miltiorrhiza, the ligusticum wallichii, the dalbergia wood and the Chinese magnoliavine fruit into a stone mortar according to the weight parts, and pounding the mixture into powder;
s2, the mashed mixed powder is put into 75% alcohol with the weight of 50 parts to be soaked for 20 days for use.
Example two
The invention provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which is mainly prepared from the following raw materials in parts by weight: 18 parts of kudzuvine root, 13 parts of safflower, 13 parts of pilose asiabell root, 12 parts of siberian solomonseal rhizome, 13 parts of astragalus root, 13 parts of red paeony root, 18 parts of turmeric root-tuber, 13 parts of red-rooted salvia root, 18 parts of szechuan lovage rhizome, 13 parts of rosewood heart wood and 13 parts of Chinese magnoliavine fruit.
S1, the preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction comprises the following steps:
putting the kudzuvine root, the safflower, the codonopsis pilosula, the sealwort, the astragalus root, the red paeony root, the turmeric root-tuber, the salvia miltiorrhiza, the ligusticum wallichii, the dalbergia wood and the Chinese magnoliavine fruit into a stone mortar according to the weight parts, and pounding the mixture into powder;
s2, the mashed mixed powder is put into 75% alcohol with the weight portion of 80 to be soaked for 23 days for use.
EXAMPLE III
The invention provides a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction, which is mainly prepared from the following raw materials in parts by weight: 20 parts of kudzuvine root, 15 parts of safflower, 15 parts of pilose asiabell root, 15 parts of siberian solomonseal rhizome, 15 parts of astragalus root, 15 parts of red paeony root, 20 parts of turmeric root-tuber, 15 parts of red-rooted salvia root, 20 parts of szechuan lovage rhizome, 15 parts of rosewood heart wood and 15 parts of Chinese magnoliavine fruit.
The preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction comprises the following steps:
s1, putting radix Puerariae, flos Carthami, radix Codonopsis, rhizoma Polygonati, radix astragali, radix Paeoniae Rubra, radix Curcumae, radix Salviae Miltiorrhizae, rhizoma Chuanxiong, lignum Dalbergiae Odoriferae, and fructus Schisandrae chinensis in a stone mortar according to the weight parts, and mashing into powder;
s2, the mashed mixed powder is put into 75% alcohol of 100 parts by weight to be soaked for 25 days.
1 clinical cases
Case selection: 60 patients with confirmed myocardial infarction were selected.
2 method of treatment
The using method comprises the following steps: the pure traditional Chinese medicine transdermal liniment prepared by the embodiment of the invention is applied to the whole body except the head; the treatment course comprises three times per day, 30 days as one treatment course, and 3 treatment courses in total, wherein the first treatment course is a remission period, the second treatment course is a recovery period, and the third treatment course is a consolidation period.
Grouping: randomly dividing 60 cases into 3 experimental groups and 3 control groups corresponding to the experimental groups respectively; wherein, each experimental group and the corresponding control group are 10 people.
Experiment group one: the formulation of example one was used;
control group one: on the basis of the formula proportion of the first formula, the amount of each medicine is reduced by 2 parts.
Experiment group two: the formulation of example two was used;
control group two: on the basis of the mixture ratio of the second formula in the embodiment, the components of one medicine, namely the kudzuvine root, are reduced.
Experiment group three: the formulation of example three was used;
control group three: on the basis of the mixture ratio of the three formulas in the example, the amount of each medicine is increased by 2 parts.
3 judgment of therapeutic effects
According to the standard of the curative effect of the diagnosis of the traditional Chinese medicine symptoms, the following standards are determined:
and (3) curing: the related symptoms are eliminated, and the body related indexes are recovered to be normal.
Improvement: body-related indices and signs improved but were not eradicated.
And (4) invalidation: no obvious change before and after clinical symptoms.
4 therapeutic results
After 3 courses of treatment, the treatment effect of the patients is detailed in the following table:
the data in the table are compared and analyzed, so that the formula using the raw materials and the proportion provided by the embodiment has higher cure rate; therefore, the pure traditional Chinese medicine transdermal liniment adopts effective raw materials and reasonable proportion, the treatment effect on myocardial infarction is obviously improved, other serious adverse events do not occur in the treatment case during the clinical observation period, and some basic indexes of the body before and after treatment have no obvious difference.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (4)
1. A pure traditional Chinese medicine transdermal liniment for treating myocardial infarction is characterized by being mainly prepared from the following raw materials in parts by weight: 15-20 parts of kudzuvine root, 10-15 parts of safflower, 12-15 parts of pilose asiabell root, 10-15 parts of rhizoma polygonati, 12-15 parts of astragalus root, 12-15 parts of red peony root, 15-20 parts of curcuma aromatica, 10-15 parts of salvia miltiorrhiza, 15-20 parts of ligusticum wallichii, 12-15 parts of dalbergia wood and 12-15 parts of schisandra chinensis.
2. The pure traditional Chinese medicine transdermal liniment for treating myocardial infarction according to claim 1 is characterized by being mainly prepared from the following raw materials, by weight, 18 parts of kudzuvine root, 13 parts of safflower, 13 parts of codonopsis pilosula, 12 parts of rhizoma polygonati, 13 parts of astragalus mongholicus, 13 parts of red paeony root, 18 parts of radix curcumae, 13 parts of salvia miltiorrhiza, 18 parts of ligusticum wallichii, 13 parts of dalbergia wood and 13 parts of schisandra chinensis.
3. A preparation method of a pure traditional Chinese medicine transdermal liniment for treating myocardial infarction is characterized by comprising the preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction in claim 1 or 2, and comprises the following steps:
s1, putting radix Puerariae, flos Carthami, radix Codonopsis, rhizoma Polygonati, radix astragali, radix Paeoniae Rubra, radix Curcumae, radix Salviae Miltiorrhizae, rhizoma Chuanxiong, lignum Dalbergiae Odoriferae, and fructus Schisandrae chinensis in a stone mortar according to the weight parts, and mashing into powder;
s2, soaking the mashed mixed powder in 50-100 parts by weight of alcohol for 20-25 days.
4. The preparation method of the pure traditional Chinese medicine transdermal liniment for treating myocardial infarction as claimed in claim 3, wherein the volume fraction of the alcohol is 75%.
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