CN112596256A - Optical coherent imaging system capable of reducing optical path dispersion and imaging method - Google Patents
Optical coherent imaging system capable of reducing optical path dispersion and imaging method Download PDFInfo
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- CN112596256A CN112596256A CN202110239421.XA CN202110239421A CN112596256A CN 112596256 A CN112596256 A CN 112596256A CN 202110239421 A CN202110239421 A CN 202110239421A CN 112596256 A CN112596256 A CN 112596256A
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- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/28—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 for polarising
- G02B27/286—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 for polarising for controlling or changing the state of polarisation, e.g. transforming one polarisation state into another
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/0025—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 for optical correction, e.g. distorsion, aberration
- G02B27/0031—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 for optical correction, e.g. distorsion, aberration for scanning purposes
Abstract
The application provides an optical coherent imaging system and method capable of reducing optical path dispersion, which comprises the following steps: the optical coherent imaging system capable of reducing the optical path dispersion comprises a light source (1), a detection unit (2), an interferometer (3), an image beam transmission unit (4), a reference beam transmission unit (5), a data acquisition and analysis unit (6), a control unit (7) and an image display unit (8), wherein a polarized light imaging technology is adopted, the optical coherent imaging system capable of reducing the optical path dispersion and working in a coordinated mode is constructed by using an optical fiber polarizer and a polarization coupler, the interference of stray light in the natural environment is not easy to occur, the dispersion of the whole optical path is reduced, the requirement on the performance of the optical fiber dispersion is greatly reduced, the real-time difficulty and the real-time cost of the technical scheme are reduced, the intensity and the signal to noise ratio of an imaging signal are improved, and the detection accuracy and the safety of operation are improved.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an optical coherent imaging system and an imaging method capable of reducing optical path dispersion.
Background
The optical coherence tomography has the characteristics of non-contact, no radiation, high detection sensitivity and no damage, and becomes a standard technology for measuring the human eye structure in the ophthalmic surgery. The femtosecond laser assisted ophthalmic surgery is an ophthalmic surgery which is realized by utilizing femtosecond laser pulses, high-precision detection of an optical coherence tomography technology and precise calculation of a computer to plan a track and automatically and intelligently realizing a plurality of key steps of the traditional ophthalmic surgery. The position and the contour of eye tissues need to be accurately scanned before, during and after the operation, and the image is displayed to a doctor.
In the current technical scheme, natural light is used for measurement, and imaging errors are easily introduced due to the influence of stray light in the environment, which is contrary to the purpose of high-precision measurement. When the optical coherent imaging system capable of reducing optical path dispersion is used for detection, crosstalk easily occurs, the interference of stray light in a natural environment is easily caused, the signal intensity and the signal to noise ratio are greatly reduced, and the imaging accuracy and the operation safety are reduced.
Disclosure of Invention
In view of the above, there is a need to provide an optical coherence imaging system capable of reducing optical path dispersion, which can improve signal strength and signal-to-noise ratio, improve imaging accuracy and surgical safety.
In order to solve the problems, the invention adopts the following technical scheme:
an optical coherence imaging system capable of reducing optical path dispersion, comprising: the device comprises a light source (1), a detection unit (2), an interferometer (3), an image beam transmission unit (4), a reference beam transmission unit (5), a data acquisition and analysis unit (6), a control unit (7) and an image display unit (8); the image beam transmission unit (4) comprises a first collimating lens (41), a polarization coupler (42), a two-dimensional galvanometer scanning unit (43), a dichroic mirror (44), a second collimating lens (45), a dispersion compensator (46) and a focusing lens (47) which are sequentially connected, and the reference beam transmission unit (5) comprises a first polarizer (51), a second polarizer (52) and a reflecting mirror (53); wherein:
the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflecting mirror (53), and then sequentially returns to the interferometer (3) through the reflecting mirror (53), the second polarizer (52) and the first polarizer (51);
the image beam is gathered at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) by the eye;
the reference beam and the image beam are subjected to coherence at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit (2) detects the coherent light and transmits the coherent light to the data acquisition and analysis unit (6), image information is generated and transmitted to the image display unit (8) to display the image information;
the control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
In some of these embodiments, the first polarizer (51) and the second polarizer (52) are polarizers.
In some of these embodiments, the imaging system has an imaging time of 0.01-0.1 seconds.
In some of these embodiments, the imaging system has a frame rate of 50-100 frames/second.
In some of these embodiments, the imaging depth of the imaging system is 8 mm.
In some of these embodiments, the imaging resolution of the imaging system is 5 μm.
In addition, the invention also provides an imaging method of the optical coherent imaging system capable of reducing optical path dispersion, which comprises the following steps:
the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflecting mirror (53), and then sequentially returns to the interferometer (3) through the reflecting mirror (53), the second polarizer (52) and the first polarizer (51);
the image beam is gathered at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) by the eye;
the reference beam and the image beam are subjected to coherence at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit (2) detects the coherent light and transmits the coherent light to the data acquisition and analysis unit (6), image information is generated and transmitted to the image display unit (8) to display the image information;
the control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
The technical scheme adopted by the application has the following effects:
compared with the prior art, the optical coherent imaging system and method capable of reducing optical path dispersion provided by the application comprise the following steps: the optical coherent imaging system capable of reducing the optical path dispersion comprises a light source (1), a detection unit (2), an interferometer (3), an image beam transmission unit (4), a reference beam transmission unit (5), a data acquisition and analysis unit (6), a control unit (7) and an image display unit (8), wherein a polarized light imaging technology is adopted, the optical coherent imaging system capable of reducing the optical path dispersion and working in a coordinated mode is constructed by using an optical fiber polarizer and a polarization coupler, the interference of stray light in the natural environment is not easy to occur, the dispersion of the whole optical path is reduced, the requirement on the performance of the optical fiber dispersion is greatly reduced, the real-time difficulty and the real-time cost of the technical scheme are reduced, the intensity and the signal to noise ratio of an imaging signal are improved, and the detection accuracy and the safety of operation are improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments of the present invention or in the description of the prior art will be briefly described below, and it is obvious that the drawings described below are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a structural diagram of an optical coherent imaging system capable of reducing optical path dispersion according to an embodiment of the present invention.
Wherein: the system comprises a light source 1, a detection unit 2, an interferometer 3, an image beam transmission unit 4, a first collimating lens 41, a polarization coupler 42, a two-dimensional galvanometer scanning unit 43, a dichroic mirror 44, a second collimating lens 45, a dispersion compensator 46, a focusing lens 47, a reference beam transmission unit 5, a first polarizer 51, a second polarizer 52, a reflecting mirror 53, a data acquisition and analysis unit 6, a control unit 7, an image display unit 8 and a human eye 9.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "horizontal", "inside", "outside", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are only for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments.
Example 1
Referring to fig. 1, a schematic structural diagram of an optical coherence imaging system capable of reducing optical path dispersion according to embodiment 1 of the present application includes: the device comprises a light source (1), a detection unit (2), an interferometer (3), an image beam transmission unit (4), a reference beam transmission unit (5), a data acquisition and analysis unit (6), a control unit (7) and an image display unit (8); the image beam transmission unit (4) comprises a first collimating lens (41), a polarization coupler (42), a two-dimensional galvanometer scanning unit (43), a dichroic mirror (44), a second collimating lens (45), a dispersion compensator (46) and a focusing lens (47) which are sequentially connected, and the reference beam transmission unit (5) comprises a first polarizer (51), a second polarizer (52) and a reflecting mirror (53).
In some of these embodiments, the fiber polarizer unit (10) is a dichroic polarizer.
It is understood that the polarizing plate is used to obtain polarized light from natural light, and the vibration direction of the polarized light coincides with the polarization direction of the polarizing plate. The polarized light imaging is not easily influenced by stray light in the environment, errors are not easily introduced, the measured signal intensity and the signal to noise ratio are greatly improved, and the accuracy of an imaging system is improved.
The application provides a degradable optical path chromatic dispersion's optical coherent imaging system, its working method as follows:
the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflector (53) through the optical fiber transmission line (9), and then sequentially returns to the interferometer (3) through the reflector (53), the second polarizer (52) and the first polarizer (51).
In some of these embodiments, the fiber transmission line (9) is a single mode fiber with a mode field diameter of 6.2 μm.
The single-mode optical fiber is made of one of quartz, glass or high-molecular polymer materials.
It will be appreciated that the core diameter of a single mode fibre is small and that the present invention uses a fibre having a diameter of 6.2 μm which can only transmit one mode. Therefore, the dispersion between modes is small, light can be transmitted for a long distance in a wide frequency band, the signal distortion is small, and the imaging accuracy of the whole optical imaging system is improved.
The image beam is focused at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) from the eye.
It can be understood that the adopted polarization coupler (42) is changed from natural light into polarized light, the vibration direction of the polarized light is consistent with the polarization direction of the polaroid, the polarized light imaging is not easily influenced by stray light in the environment, errors are not easily introduced, the measured signal intensity and the signal to noise ratio are greatly improved, and the accuracy of the imaging system is improved.
It will be appreciated that the present invention employs a two-dimensional galvanometer scanning unit (43) which deflects at a very high rate and thus greatly increases the overall scanning rate, resulting in high imaging rates and short imaging times, meaning that an image can be generated which provides timely and thus useful feedback to the surgeon regarding the progress of the ophthalmic procedure so that the surgeon can modify the procedure in response to the feedback and can view in real time during the imaging of the structures of the human eye. During the femtosecond laser-assisted ophthalmic surgery, a doctor can observe the surgical process of a patient in real time, simultaneously two optical coherence tomography measurement systems coordinate to image the human eye structure in real time, and the imaging of a three-dimensional model of the human eye structure and the observation of the surgical implementation process can be completed simultaneously.
The reference beam and the image beam are coherent at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit 2 detects the coherent light and transmits the coherent light to the data acquisition and analysis unit 6 through the electric signal path 10, and image information is generated and transmitted to the image display unit (8) to display the image information.
The control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
Further, the imaging time of the imaging system is 0.01-0.1 second.
Further, the frame rate of the imaging system is 50-100 frames/second.
It will be appreciated that a typical refresh rate used for live video images is about 24 frames/second. Thus, an imaging system providing images at a refresh rate or frame rate of 50-100 frames/second may provide high resolution live images to a physician. While systems with frame rates or refresh rates much less than 20 to 25 frames/second may not be considered live video imaging, but rather as unstable, jumpy images, possibly even distracting the physician from the ophthalmic surgery.
Further, the imaging depth of the imaging system is 8 mm. The imaging resolution of the imaging system is 5 mu m, the problem that the imaging of the human eye structure with depth and high resolution cannot be considered in the prior art is solved, preoperative high-precision detection and intraoperative whole-eye real-time imaging can be realized, and the accuracy and safety of the operation are improved.
The application provides a degradable optical path dispersive optical coherence imaging system, adopt polarized light imaging technique, use through optical fiber polarizer and polarization coupler constitutes the degradable optical path dispersive optical coherence imaging system of coordination work, be difficult for receiving stray light's among the natural environment interference, the dispersion of whole light path has been reduced, also greatly reduced the requirement to optical fiber dispersibility performance, the real-time degree of difficulty and the cost of technical scheme have been reduced, imaging signal intensity and SNR have been improved, the accuracy of detection and the security of performing the operation have been improved.
Example 2
The application also provides an imaging method of the optical coherent imaging system capable of reducing optical path dispersion, which comprises the following steps:
step S110: the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
step S120: the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflector (53) through the optical fiber transmission line 9, and then sequentially returns to the interferometer (3) through the reflector (53), the second polarizer (52) and the first polarizer (51)
Step S130: the image beam is gathered at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) by the eye.
Step S140: the reference beam and the image beam are coherent at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit 2 detects the coherent light and transmits the coherent light to the data acquisition and analysis unit 6 through the electric signal path 10, and image information is generated and transmitted to the image display unit (8) to display the image information.
Step S150: the control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
The optical coherent imaging method provided by the application adopts a polarized light imaging technology, and the optical coherent imaging system capable of reducing the optical path dispersion and working in coordination is constructed by using the optical fiber polarizer and the polarization coupler, so that the interference of stray light in the natural environment is not easy to occur, the dispersion of the whole optical path is reduced, the requirement on the optical fiber dispersion performance is greatly reduced, the real-time difficulty and cost of the technical scheme are reduced, the imaging signal intensity and the signal to noise ratio are improved, and the detection accuracy and the operation safety are improved.
The above are merely examples of the present application and are not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.
Claims (7)
1. An optical coherence imaging system capable of reducing optical path dispersion, comprising: the device comprises a light source (1), a detection unit (2), an interferometer (3), an image beam transmission unit (4), a reference beam transmission unit (5), a data acquisition and analysis unit (6), a control unit (7) and an image display unit (8); the image beam transmission unit (4) comprises a first collimating lens (41), a polarization coupler (42), a two-dimensional galvanometer scanning unit (43), a dichroic mirror (44), a second collimating lens (45), a dispersion compensator (46) and a focusing lens (47) which are sequentially connected, and the reference beam transmission unit (5) comprises a first polarizer (51), a second polarizer (52) and a reflecting mirror (53); wherein:
the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflecting mirror (53), and then sequentially returns to the interferometer (3) through the reflecting mirror (53), the second polarizer (52) and the first polarizer (51);
the image beam is gathered at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) by the eye;
the reference beam and the image beam are subjected to coherence at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit (2) detects the coherent light and transmits the coherent light to the data acquisition and analysis unit (6), image information is generated and transmitted to the image display unit (8) to display the image information;
the control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
2. The system of claim 1, wherein the first polarizer (51) and the second polarizer (52) are polarizers.
3. The optical coherence imaging system capable of reducing optical path dispersion according to claim 1, wherein the imaging time of the imaging system is 0.01-0.1 second.
4. The optical coherence imaging system capable of reducing optical path dispersion according to claim 1, wherein the frame rate of the imaging system is 50-100 frames/sec.
5. The optical coherence imaging system capable of reducing optical path dispersion according to claim 1, wherein the imaging depth of the imaging system is 8 mm.
6. The optical coherence imaging system capable of reducing optical path dispersion according to claim 1, wherein an imaging resolution of the imaging system is 5 μm.
7. An imaging method of the optical coherence imaging system capable of reducing optical path dispersion according to any one of claims 1 to 6, comprising:
the light source (1) generates a scanning wavelength beam which is divided into an image beam and a reference beam by the interferometer (3);
the reference beam sequentially enters the first polarizer (51), the second polarizer (52) and the reflecting mirror (53), and then sequentially returns to the interferometer (3) through the reflecting mirror (53), the second polarizer (52) and the first polarizer (51);
the image beam is gathered at the eye through the first collimating lens (41), the polarization coupler (42), the two-dimensional galvanometer scanning unit (43), the dichroic mirror (44), the second collimating lens (45), the dispersion compensator (46) and the focusing lens (47) in sequence, and the image beam is returned to the interferometer (3) by the eye;
the reference beam and the image beam are subjected to coherence at the interferometer (3) to generate coherent light, the coherent light is transmitted to the detection unit (2), the detection unit (2) detects the coherent light and transmits the coherent light to the data acquisition and analysis unit (6), image information is generated and transmitted to the image display unit (8) to display the image information;
the control unit (7) generates a control signal according to the image information generated by the image display unit (8) and transmits the control signal to the whole optical coherent imaging system capable of reducing optical path dispersion for real-time adjustment.
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| KR20050043164A (en) * | 2003-11-05 | 2005-05-11 | 한국전기연구원 | Oct(optical coherence tomography) system using a ccd(charge coupled device) camera |
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Application publication date: 20210402 |