CN112538666A - Reusable nano-fiber film for antibacterial biological protective mask and manufacturing method thereof - Google Patents
Reusable nano-fiber film for antibacterial biological protective mask and manufacturing method thereof Download PDFInfo
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
- D01F6/44—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds
- D01F6/50—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyalcohols, polyacetals or polyketals
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D13/00—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
- A41D13/05—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
- A41D13/11—Protective face masks, e.g. for surgical use, or for use in foul atmospheres
- A41D13/1192—Protective face masks, e.g. for surgical use, or for use in foul atmospheres with antimicrobial agent
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D31/00—Materials specially adapted for outerwear
- A41D31/04—Materials specially adapted for outerwear characterised by special function or use
- A41D31/14—Air permeable, i.e. capable of being penetrated by gases
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D31/00—Materials specially adapted for outerwear
- A41D31/04—Materials specially adapted for outerwear characterised by special function or use
- A41D31/30—Antimicrobial, e.g. antibacterial
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0015—Electro-spinning characterised by the initial state of the material
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F1/00—General methods for the manufacture of artificial filaments or the like
- D01F1/02—Addition of substances to the spinning solution or to the melt
- D01F1/10—Other agents for modifying properties
- D01F1/103—Agents inhibiting growth of microorganisms
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
- A41D2500/00—Materials for garments
- A41D2500/50—Synthetic resins or rubbers
- A41D2500/52—Synthetic resins or rubbers in sheet form
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Abstract
The invention provides a reusable nano-fiber film for an antibacterial biological protective mask and a preparation method thereof, wherein the preparation method comprises the following steps: after preparing the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent, taking polyvinyl butyral (PVB) powder, slowly adding absolute ethyl alcohol, heating and stirring for about 1.5-3 hours until the PVB is completely dissolved, and preparing a spinning solution with the weight of 7 percent; mixing the prepared PVB solution with the CS-Ag-ZnO composite finishing liquid, heating and stirring for 8-9h, setting the stirring temperature to be 70-90 ℃, standing at room temperature for 7-9h for defoaming, and obtaining a CS/PVA mixed solution; after the mixed solution is placed and cooled to normal temperature, the mixed solution is placed on an electrostatic spinning device to obtain a uniform PVB/CS-Ag-ZnO nanofiber membrane.
Description
Technical Field
The invention relates to a medical protective material, in particular to a reusable antibacterial biological protective mask material.
Background
The new crown pneumonia epidemic situation in the early 2020 causes the sudden increase of the mask demand, which leads to the high price and the short supply of the mask raw material melt-blown cloth. The active antibacterial mask plays an important role in relieving the problems of insufficient mask raw materials, waste pollution and the like in the epidemic situation of the sudden respiratory infectious diseases. The active antibacterial mask is characterized in that antibacterial components are added into a mask filtering material or a positive pressure air supply mode is adopted, so that the mask is endowed with an active antibacterial function.
Common medical surgical masks in the market at present have no antibacterial effect, bacteria trapped on the masks can normally reproduce, so the masks can be worn for 8 hours generally, and after 8 hours, the total bacterial colony number of the common medical surgical masks can exceed the requirements of YY0469-2011 medical surgical mask technical requirement which is less than or equal to 100 CFU/g. And the pathogenic microorganism trapped on the mask is easy to diffuse again to cause secondary pollution. Medical protective masks are often required to be disposable, which also increases the mask demand under an outbreak of an associated epidemic. And the disposable use causes a large amount of biological waste, which poses serious threats to the environment and people.
Emerging masks that use nanofiber membranes as materials such as: chinese patent document CN111424378A (application number: 202010332597.5) discloses a nanofiber membrane for a mask and a manufacturing method thereof, wherein the nanofiber membrane comprises a base layer and a nanofiber membrane layer arranged on the base layer, the base layer is non-woven fabric, and the nanofiber membrane layer is combined with the base layer in an electrostatic spinning mode; the diameter of the fiber of the nano fiber film layer is 50-200 nm, and the aperture is 30-90 nm. Because of no antibacterial effect, the mask is only prolonged in time and cannot be reused.
Disclosure of Invention
In order to solve the problems, the invention aims to provide the reusable antibacterial nanofiber membrane for the biological protective mask, which has the advantages of simple process, reusability and good antibacterial effect.
In order to achieve the purpose, the invention discloses the following technical contents:
a preparation method of a reusable antibacterial nanofiber membrane for biological protective masks comprises the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, heating and stirring for 1.5-3 hours until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid according to the volume ratio of 70:30, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8-9 hours, setting the stirring temperature to be 70-90 ℃, standing at room temperature for 8-9 hours, and defoaming to obtain a chitosan/polyvinyl alcohol (CS/PVA) mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, placing the mixed solution on an electrostatic spinning device to obtain a uniform PVB/CS-Ag-ZnO nanofiber membrane.
Further, the parameters of the electrostatic spinning device are set as follows: the solution perfusion speed is 1-3ml/h, the receiving distance is 24-26cm, the voltage is 20-40kV, the sliding table moving speed is 90-120cn/min, and the roller rotating speed is 40-60 r/min.
Furthermore, when the PVB/CS-Ag-ZnO nano-fiber film is prepared, the temperature is 22-24 ℃, and the relative humidity is 40-50%.
The nanofiber membrane for the reusable antibacterial biological protective mask is prepared according to the method.
The invention has the following beneficial effects:
(1) the nanofiber membrane prepared by the electrostatic spinning method has excellent air permeability when the concentration is 7wt%, the filtering efficiency of 0.3 micron NaCl aerosol can reach 97%, the air permeability resistance is only 100 Pa, and the nanofiber membrane is an excellent filtering material;
(2) compared with common masks on the market, the mask has better filtering efficiency, can effectively inhibit flora reproduction, and avoids the possibility that high-activity pathogenic microorganisms are spread because the used masks are brought back to home;
(3) the mask manufactured by the invention can be worn for 8 hours every day and can be reused for 4 days without any disinfection treatment, the total bacterial community number in the period accords with YY0469-2011 medical surgical mask technical requirement which is not more than 100 CFU/g, and the filtering efficiency accords with YY0469-2011 medical surgical mask technical requirement which is not less than 95%;
(4) the preparation method is simple, the production cost is low, the safe and repeated use of the disposable mask is realized without large-scale upgrading of the existing production line and production flow of the medical mask, the mask capacity is equivalently expanded, and the method has good social benefits.
Drawings
FIG. 1 shows the results of culturing the microorganism indicators of example 6
Detailed Description
The invention is described below by means of specific embodiments. Unless otherwise specified, the technical means used in the present invention are well known to those skilled in the art. In addition, the embodiments should be considered illustrative, and not restrictive, of the scope of the invention, which is defined solely by the claims. It will be apparent to those skilled in the art that various changes or modifications in the components and amounts of the materials used in these embodiments can be made without departing from the spirit and scope of the invention.
Example 1
A preparation method of a reusable antibacterial biological protective mask material comprises the following steps:
(1) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, magnetically stirring for about 2 hours in water bath heating until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(2) and (3) sucking 3mL of the PVB spinning solution obtained in the step (1) by using a disposable syringe with the capacity of 10mL, and placing the PVB spinning solution on an electrostatic spinning device to obtain a uniform PVB nanofiber membrane.
Example 2
A preparation method of a reusable antibacterial biological protective mask material comprises the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, magnetically stirring for about 2 hours in water bath heating until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid according to a volume ratio of 90% to 10%, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8 hours, setting the stirring temperature to 80 ℃, standing at room temperature overnight for defoaming, and obtaining a CS/PVA mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, sucking 3mL of the solution by using a disposable syringe with the capacity of 10mL, and placing the solution on an electrostatic spinning device to obtain the uniform PVB/CS-Ag-ZnO nanofiber membrane.
Example 3
A preparation method of a reusable antibacterial biological protective mask material comprises the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, magnetically stirring for about 2 hours in water bath heating until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid in a ratio of 80% to 20%, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8 hours, setting the stirring temperature to 80 ℃, standing at room temperature for overnight defoaming, and obtaining a CS/PVA mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, sucking 3mL of the solution by using a disposable syringe with the capacity of 10mL, and placing the solution on an electrostatic spinning device to obtain the uniform PVB/CS-Ag-ZnO nanofiber membrane.
Example 4
A preparation method of a reusable antibacterial biological protective mask material comprises the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, magnetically stirring for about 2 hours in water bath heating until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid in a ratio of 70% to 30%, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8 hours, setting the stirring temperature to 80 ℃, standing at room temperature overnight for defoaming, and obtaining a CS/PVA mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, sucking 3mL of the solution by using a disposable syringe with the capacity of 10mL, and placing the solution on an electrostatic spinning device to obtain the uniform PVB/CS-Ag-ZnO nanofiber membrane.
The parameters of the electrostatic spinning device are as follows: the solution filling speed is 2ml/h, the receiving distance is 25cm, the voltage is 30kV, the moving speed of the sliding table is 100cn/min, the rotating speed of the roller is 50r/min, the environmental temperature is controlled to be 23 ℃ and 1 ℃ and the relative humidity is controlled to be 45 +/-5%.
Example 5
A preparation method of a reusable antibacterial biological protective mask material comprises the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, magnetically stirring for about 2 hours in water bath heating until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid in a ratio of 60% to 40%, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8 hours, setting the stirring temperature to 80 ℃, standing at room temperature overnight for defoaming, and obtaining a CS/PVA mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, sucking 3mL of the solution by using a disposable syringe with the capacity of 10mL, and placing the solution on an electrostatic spinning device to obtain the uniform PVB/CS-Ag-ZnO nanofiber membrane.
The parameters of the electrostatic spinning device are as follows: the solution filling speed is 2ml/h, the receiving distance is 25cm, the voltage is 30kV, the moving speed of the sliding table is 100cn/min, the rotating speed of the roller is 50r/min, the environmental temperature is controlled to be 23 ℃ and 1 ℃ and the relative humidity is controlled to be 45 +/-5%.
Test example 1
Reference is made to GB/T20944.3-2008 section 3 for evaluation of antibacterial properties of textiles: oscillation method. The antibacterial property of the suspension of the uniform PVB/CS-Ag-ZnO nanofiber films obtained in examples 2-5 was tested by using the uniform PVB nanofiber film obtained in example 1 as a control sample.
(1) Preparing a suspension of staphylococcus aureus, escherichia coli and phage MS2 according to a specified method, and adjusting the concentration range to be 3-4 multiplied by 105 CFU/mL;
(2) adding a sterilized sample into a flask containing a bacterial suspension and a buffer solution, and oscillating and contacting for 18 h;
(3) directly or after dilution, taking a proper amount of liquid to coat the liquid on a nutrient broth solid plate, culturing for 24h at 37 ℃, observing and counting, and calculating the antibacterial rate of a test sample;
(4) after the sample is in oscillation contact with the bacterial suspension for 18 hours, taking out and airing, and putting into 2.5% glutaraldehyde solution for fixing for 2 hours; then eluting with ethanol, drying, spraying gold, and observing the number of bacteria on the sample by using a scanning electron microscope;
(5) preparing an escherichia coli suspension by referring to a carrier spray quantitative sterilization test operation procedure of 'disinfection technical specification', and adjusting the concentration range of the escherichia coli suspension to be 1-5 multiplied by 108 CFU/mL;
(6) sterilizing each sample membrane, fixing on a bracket, placing an aerosol generator containing bacterial suspension at a position 15cm away from the sample, spraying towards the sample, placing the sample sprayed with the bacterial aerosol for 0.5h, placing the sample into a triangular flask containing buffer solution, oscillating for 2 min, coating a proper amount of liquid on a nutrient broth solid plate, culturing, counting, and calculating the antibacterial rate.
The results of the antibacterial performance test are as follows:
| sample film | Staphylococcus aureus inhibitory rate (%) | Escherichia coli inhibitory rate (%) |
| Example 1 | Example 1 is a control | Example 1 is a control |
| Example 2 | 57.07 | 32.55 |
| Example 3 | 94.75 | 99.67 |
| Example 4 | 96.6 | 99.03 |
| Example 5 | 96.31 | 96.80 |
Test example 2
The filtration efficiency and airflow resistance of the uniform PVB/CS-Ag-ZnO nanofiber membranes obtained in examples 2-5 were tested, respectively, using the uniform PVB nanofiber membrane obtained in example 1 as a control sample. An automatic filter material detector is adopted, an effective area with the testing area of 15cm multiplied by 15cm is set, electrically neutral monodisperse NaCI solid aerosol and oil aerosol with the mass median diameter of 0.24 +/-0.06 um are sent to the fiber membrane to be tested in the embodiment 1-5, and the filtering piezoresistance is obtained by a flow meter and two electronic pressure sensors through cooperative analysis and testing. All filtration tests were performed at 24. + -. 2 ℃ with gas flow control at 85. + -.2L/min for 1min per filtration test.
The results of the filtration efficiency and airflow resistance tests are as follows:
| sample film | Filtration efficiency (%) | Air flow resistance (Pa) |
| Example 1 (control group) | 98.9659 | 88 |
| Example 2 | 99.3644 | 97 |
| Example 3 | 98.9761 | 91 |
| Example 4 | 98.7682 | 102 |
| Example 5 | 98.6365 | 107 |
Example 6
A plurality of subjects are recruited at random, a medical surgical mask sold in the market is used as a test group, a wearing test of daily working and living scenes is carried out by using the mask made of the PVB/CS-Ag-ZnO nanofiber membrane, the mask is worn for 8 hours every day, and the protective performance and the microorganism content index of the mask after the mask is repeatedly used in the day are respectively tracked and measured, so that the reusability conditions of the medical surgical mask and the antibacterial mask are contrastingly analyzed.
The test results are as follows:
referring to the comparison example, with the increase of the use time, the filtration efficiency of the common medical surgical mask is obviously reduced, the total bacterial colony number is multiplied, and after the mask is worn for 8 hours, the mask cannot reach the YY0469-2011 technical requirement of the medical surgical mask, so the mask cannot be worn continuously. The mask prepared by using the PVB/CS-Ag-ZnO nanofiber membrane only slightly reduces the filtration efficiency within 4 days, but still meets the requirement that YY0469-2011 medical surgical mask technical requirement is not less than 95%, and the total bacterial colony number exceeds YY0469-2011 medical surgical mask technical requirement by not more than 100 CFU/g (YY 0469-2011) on the fourth day according to the table and the attached figure 1, so that the mask has obvious antibacterial and repeated use effects.
Claims (4)
1. A preparation method of a reusable antibacterial nanofiber membrane for biological protective masks is characterized by comprising the following steps:
(1) under the condition of normal temperature stirring, 0.05-0.2g of chitosan is dissolved in 15-25ml of acetic acid aqueous solution or formic acid aqueous solution with volume concentration of 0.5-1%, 0.5-2.5ml of polyethylene glycol and 0.01-0.06g of hydroxyethyl cellulose are sequentially added, the mixture is uniformly stirred, 1-2ml of silver nitrate aqueous solution with concentration of 0.5-2M is added, the mixture is uniformly stirred, the mixture reacts for 30-60s under the microwave condition of 100 plus materials and 115 ℃, the temperature is naturally reduced to the room temperature, 0.01-0.8g of nano zinc oxide is added, the mixture is continuously stirred at the room temperature until the system is transparent, and the nano zinc oxide-silver-loaded chitosan (CS-Ag-ZnO) composite antibacterial agent is obtained;
(2) slowly adding absolute ethyl alcohol into polyvinyl butyral (PVB) powder, heating and stirring for 1.5-3 hours until the PVB is completely dissolved, and preparing a 7wt% spinning solution;
(3) mixing the PVB solution prepared in the step (2) with the CS-Ag-ZnO composite finishing liquid according to the volume ratio of 60:40-80:20, placing the mixture in a constant-temperature heating magnetic stirrer, heating and stirring for 8-9 hours, setting the stirring temperature to be 70-90 ℃, standing at room temperature for 8-9 hours, and defoaming to obtain a chitosan/polyvinyl alcohol (CS/PVA) mixed solution;
(4) and (4) after the CS/PVA mixed solution obtained in the step (3) is kept stand and cooled to normal temperature, placing the mixed solution on an electrostatic spinning device to obtain a uniform PVB/CS-Ag-ZnO nanofiber membrane.
2. The method for preparing the nanofiber membrane for the reusable antibacterial biological protective mask according to claim 1, wherein the electrostatic spinning device parameters are set as follows: the solution perfusion speed is 1-3ml/h, the receiving distance is 24-26cm, the voltage is 20-40kV, the sliding table moving speed is 90-120cn/min, and the roller rotating speed is 40-60 r/min.
3. The method for preparing the nanofiber membrane for the reusable antibacterial biological protective mask according to claim 1, wherein the PVB/CS-Ag-ZnO nanofiber membrane is prepared at an ambient temperature of 22-24 ℃ and a relative humidity of 40-50%.
4. A reusable nanofiber membrane for an antibacterial biological protective mask, manufactured by the manufacturing method according to claims 1-3.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114045611A (en) * | 2021-11-17 | 2022-02-15 | 广东粤港澳大湾区国家纳米科技创新研究院 | Preparation method of zinc oxide nanofiber membrane |
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| CN114045611A (en) * | 2021-11-17 | 2022-02-15 | 广东粤港澳大湾区国家纳米科技创新研究院 | Preparation method of zinc oxide nanofiber membrane |
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