CN112485301A - Test method, system, equipment and medium of electrochemical test device - Google Patents
Test method, system, equipment and medium of electrochemical test device Download PDFInfo
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Abstract
The application discloses a test method, a system, equipment and a medium of an electrochemical test device, which are applied to the electrochemical test device, wherein the electrochemical test device comprises: the tester comprises a tester and a test strip which is inserted into an interface on the tester and then forms connection with the tester; the test method comprises the following steps: when the analyte concentration of the sample is tested, the impedance value of the electric loop of the sample at the sample inlet and the impedance value of the electric loop of the sample at the sample inlet are obtained by the tester; a target impedance value for the sample at the sample inlet is determined using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value. Obviously, because the measurement method can offset the impedance difference generated by the test strip electrode in the printing process, the method can make the test result of the sample analyte concentration more accurate and reliable.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a testing method, a testing system, testing equipment and a testing medium of an electrochemical testing device.
Background
At present, when an electrochemical testing device is used to measure blood components of a person through an electrochemical method, a test strip and a tester are generally arranged in the electrochemical testing device, wherein in the process of measuring a sample by using the tester, the sample needs to be dripped to an injection port of the test strip, and because relevant chemical substances are arranged at the injection port, a corresponding impedance value is generated when the sample is dripped to the injection port of the test strip. In the process, the electrode at the bottom of the test strip is utilized to enable the sample inlet in the test strip and the electrode to form a communicated electric loop, and at the moment, the tester can measure the analyte concentration of the sample by measuring the impedance value of the electric loop.
However, if the electrochemical measurement method in the prior art is used, the tester can only measure the analyte concentration of the sample through the electrical circuit including the sample inlet and the electrodes, and because the impedance characteristics of the electrodes of the test strip will generate different differences during the printing process, the impedance error carried by the electrodes of the test strip will be introduced into the analyte concentration measurement result of the sample, and thus the analyte concentration measurement result of the sample will be inaccurate and unreliable. At present, no effective solution exists for the above technical problems.
Therefore, it is an urgent technical problem to be solved by those skilled in the art to avoid the influence of the impedance difference generated in the printing process of the strip electrode on the sample analyte concentration test result.
Disclosure of Invention
In view of the above, the present invention provides a method, a system, a device and a medium for testing an electrochemical testing device, so as to avoid the influence of the impedance difference generated by the strip electrode during the printing process on the test result of the analyte concentration of the sample. The specific scheme is as follows:
a method of testing an electrochemical test device, applied to an electrochemical test device, the electrochemical test device comprising: the test strip is inserted into an interface on the tester and then electrically connected with the tester; the test method comprises the following steps:
when the analyte concentration of a sample is tested, acquiring the impedance value of an electric circuit containing the sample at a sample inlet and the impedance value of an electric circuit not containing the sample at the sample inlet in the test strip by using the tester;
determining a target impedance value for the sample at the sample inlet using an impedance value of the electrical circuit containing the sample at the sample inlet and an impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
Preferably, the test meter comprises: the device comprises a first impedance measuring module, a second impedance measuring module, a first signal switching module and a second signal switching module; the test strip comprises a first electrode, a second electrode and a third electrode, wherein the first electrode, the second electrode and the third electrode are communicated with the sample inlet, the first electrode is provided with a first electric contact end and a second electric contact end, the second electrode is provided with a third electric contact end and a fourth electric contact end, and the third electrode is provided with a fifth electric contact end;
when the test strip is inserted into the interface of the tester, the connection relationship between the test strip and the tester is as follows:
the first impedance measuring module is connected with one end of the first signal switching module, and the other end of the first signal switching module is connected with the first electric contact end or the third electric contact end in a switchable manner;
the second impedance measurement module is connected with the fifth electric contact terminal;
one end of the second signal switching module is grounded, and the other end of the second signal switching module is switchably connected to the second electrical contact end or the fourth electrical contact end.
Preferably, the first signal switching module and/or the second signal switching module is/are a single-pole double-throw switch.
Preferably, the first impedance measurement module includes: the first DAC, the first ADC, the first operational amplifier, the first capacitor and the first resistor;
a first input end of the first operational amplifier is connected to the first DAC, a second input end of the first operational amplifier is connected to one end of the first signal switching module, a first end of the first capacitor, and a first end of the first resistor, respectively, and an output end of the first operational amplifier is connected to a second end of the first capacitor, a second end of the first resistor, and the first ADC, respectively;
correspondingly, the second impedance measurement module comprises: the second DAC, the second ADC, the second operational amplifier, the second capacitor and the second resistor;
the first input end of the second operational amplifier is connected with the second DAC, the second input end of the second operational amplifier is connected with the fifth electrical contact end, the first end of the second capacitor and the first end of the second resistor respectively, and the output end of the second operational amplifier is connected with the second end of the second capacitor, the second end of the second resistor and the second ADC respectively.
Preferably, the process of obtaining an impedance value of an electrical circuit in the test strip containing the sample at the sample inlet by using the tester includes:
triggering the other end of the first signal switching module to be connected with the first electric contact end, and connecting the other end of the second signal switching module with the fourth electric contact end to form a first electric loop;
determining a first impedance value of the first electrical circuit in the test strip containing the sample at the sample inlet from the first electrical circuit;
triggering the other end of the first signal switching module to be connected with the third electric contact end, and connecting the other end of the second signal switching module with the second electric contact end to form a second electric loop;
determining a second impedance value of the second electrical circuit in the test strip containing the sample at the sample inlet from the second electrical circuit.
Preferably, the process of obtaining an impedance value of an electrical circuit of the test strip not containing the sample at the sample inlet by using the tester includes:
triggering the other end of the first signal switching module to be connected with the first electric contact end, and connecting the other end of the second signal switching module with the second electric contact end to form a third electric loop;
determining from the third electrical circuit a third impedance value of the third electrical circuit in the test strip that does not contain the sample at the sample inlet;
triggering the other end of the first signal switching module to be connected with the third electric contact end, and connecting the other end of the second signal switching module with the fourth electric contact end to form a fourth electric loop;
determining a fourth impedance value of the fourth electrical circuit in the test strip that does not contain the sample at the sample inlet from the fourth electrical circuit.
Preferably, the process of determining a target impedance value of the sample at the sample inlet using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet comprises:
determining the target impedance value of the sample at the sample inlet using the first impedance value, the second impedance value, the third impedance value, and the fourth impedance value based on a target model;
wherein the mathematical expression of the target model is:
RHB＝[R01+R02-(R03+R04)]/2；
in the formula, RHBIs the target impedance value, R01Is the first impedance value, R02Is the second impedance value, R03Is the third impedance value, R04Is the fourth impedance value.
Correspondingly, the invention also discloses a test system of the electrochemical test device, which is applied to the electrochemical test device, and the electrochemical test device comprises: the test strip is inserted into an interface on the tester and then electrically connected with the tester; the test system includes:
the impedance value acquisition module is used for acquiring the impedance value of an electric circuit containing the sample at the sample inlet and the impedance value of an electric circuit not containing the sample at the sample inlet in the test strip by using the tester when the analyte concentration of the sample is tested;
a concentration test module for determining a target impedance value of the sample at the sample inlet using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
Correspondingly, the invention also discloses a test device of the electrochemical test device, which comprises:
a memory for storing a computer program;
a processor for implementing the steps of a method of testing an electrochemical testing device as disclosed above when executing said computer program.
Accordingly, the present invention also discloses a computer readable storage medium having stored thereon a computer program which, when being executed by a processor, carries out the steps of a method for testing an electrochemical testing device as disclosed in the foregoing.
It can be seen that, in the testing method provided by the present invention, when the analyte concentration of the sample is tested, the tester is first used to obtain the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet in the test strip, and then the tester can determine the target impedance value of the sample at the sample inlet by using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet, and test the analyte concentration of the sample according to the target impedance value of the sample at the sample inlet. Obviously, the impedance difference generated in the printing process of the test strip electrode can be counteracted by using the impedance value of the electric circuit containing the sample at the sample inlet and the impedance value of the electric circuit not containing the sample at the sample inlet by the measuring method, so that the influence of the impedance difference generated in the printing process of the test strip electrode on the sample analyte concentration test result can be avoided by the method, and the sample analyte concentration test result can be more accurate and reliable. Correspondingly, the test system, the test equipment and the test medium of the electrochemical test device provided by the invention also have the beneficial effects.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a flow chart of a method for testing an electrochemical testing device according to an embodiment of the present invention;
FIG. 2 is a block diagram of an electrochemical testing apparatus according to an embodiment of the present invention;
FIG. 3 is a block diagram of another electrochemical testing apparatus provided in accordance with an embodiment of the present invention;
FIG. 4 is a schematic diagram of a first electrical circuit;
FIG. 5 is a schematic diagram of a second electrical circuit;
FIG. 6 is a schematic diagram of a third electrical circuit;
FIG. 7 is a schematic diagram of a fourth electrical loop;
FIG. 8 is an electrical equivalent model diagram of a test strip;
FIG. 9 is a block diagram of a testing system of an electrochemical testing apparatus according to an embodiment of the present invention;
fig. 10 is a block diagram of a testing apparatus of an electrochemical testing device according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, fig. 1 is a flowchart illustrating a testing method of an electrochemical testing apparatus according to an embodiment of the present invention, applied to the electrochemical testing apparatus, the electrochemical testing apparatus including: the tester comprises a tester and a test strip which is inserted into an interface on the tester and then forms electrical connection with the tester; the test method comprises the following steps:
step S11: when the analyte concentration of a sample is tested, the impedance value of an electric circuit containing the sample at the sample inlet and the impedance value of an electric circuit not containing the sample at the sample inlet in the test strip are obtained by using the tester;
step S12: a target impedance value for the sample at the sample inlet is determined using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
In this embodiment, a testing method of an electrochemical testing apparatus is provided, by which the accuracy and reliability of the test result of the analyte concentration in a sample can be significantly improved. In the test method, when the analyte concentration of a sample needs to be tested, firstly, a tester is used for obtaining the impedance value of an electric loop containing the sample at the sample inlet and the impedance value of an electric loop not containing the sample at the sample inlet in a test strip.
It is understood that the electrical circuit in the strip containing the sample at the sample inlet is an electrical circuit consisting of the sample at the sample inlet and the electrodes in the strip, and the electrical circuit in the strip not containing the sample at the sample inlet is an electrical circuit consisting of the electrodes in the strip. Because the impedance value of the electrode in a single test strip cannot be changed, when the impedance value of the electric circuit containing the sample at the sample inlet and the impedance value of the electric circuit not containing the sample at the sample inlet in the test strip are obtained by the tester, the target impedance value of the sample at the sample inlet can be determined by using the impedance value of the electric circuit containing the sample at the sample inlet and the impedance value of the electric circuit not containing the sample at the sample inlet in the test strip.
It can be thought that when the tester determines the target impedance value of the sample at the sample inlet by using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet, the impedance difference generated in the test strip in the printing process due to the electrode can be cancelled, so that the influence on the test result of the test strip due to the impedance difference generated in the printing process of the electrode in the test strip can be avoided, and the test result of the sample analyte concentration can be more accurate and reliable.
It can be seen that, in the testing method provided in this embodiment, when the analyte concentration of the sample is tested, first, the impedance value of the electrical circuit including the sample at the sample inlet and the impedance value of the electrical circuit not including the sample at the sample inlet in the test strip are obtained by using the tester, then, the tester can determine the target impedance value of the sample at the sample inlet by using the impedance value of the electrical circuit including the sample at the sample inlet and the impedance value of the electrical circuit not including the sample at the sample inlet, and test the analyte concentration of the sample according to the target impedance value of the sample at the sample inlet. Obviously, the impedance difference generated in the printing process of the test strip electrode can be counteracted by using the impedance value of the electric circuit containing the sample at the sample inlet and the impedance value of the electric circuit not containing the sample at the sample inlet by the measuring method, so that the influence of the impedance difference generated in the printing process of the test strip electrode on the sample analyte concentration test result can be avoided by the method, and the sample analyte concentration test result can be more accurate and reliable.
Based on the above embodiments, the present embodiment further describes and optimizes the technical solution, please refer to fig. 2, and fig. 2 is a structural diagram of an electrochemical testing apparatus provided by an embodiment of the present invention. As a preferred embodiment, the test meter comprises: a first impedance measuring module 11, a second impedance measuring module 12, a first signal switching module 13, and a second signal switching module 14; the test strip comprises a first electrode 21, a second electrode 22 and a third electrode 23 which are communicated with a sample inlet, wherein the first electrode 21 is provided with a first electric contact end 101 and a second electric contact end 102, the second electrode 22 is provided with a third electric contact end 201 and a fourth electric contact end 202, and the third electrode 23 is provided with a fifth electric contact end 301;
when the strip is inserted into the interface of the tester, the connection relationship between the strip and the tester is as follows:
the first impedance measuring module 11 is connected to one end of the first signal switching module 13, and the other end of the first signal switching module 13 is switchably connected to the first electrical contact end 101 or the third electrical contact end 201;
the second impedance measuring module 12 is connected with the fifth electrical contact end 301;
one end of the second signal switching module 14 is grounded, and the other end of the second signal switching module 14 is switchably connected to the second electrical contact terminal 102 or the fourth electrical contact terminal 202.
In the present embodiment, an electrochemical test device corresponding to the above test method is provided, and specifically, a test strip and a tester are provided in the electrochemical test device. Wherein the strip comprises a first electrode 21, a second electrode 22 and a third electrode 23, the first electrode 21 has a first electrical contact end 101 and a second electrical contact end 102, the second electrode 22 has a third electrical contact end 201 and a fourth electrical contact end 202, and the third electrode 23 has a fifth electrical contact end 301; the tester includes a first impedance measuring module 11, a second impedance measuring module 12, a first signal switching module 13, and a second signal switching module 14.
When the test strip is inserted into the interface of the tester, the first impedance measurement module 11 in the tester is connected to one end of the first signal switching module 13, and the other end of the first signal switching module 13 can be connected to the first electrical contact end 101 of the first electrode 21 in the test strip or connected to the third electrical contact end 201 of the second electrode 22 in the test strip; the second impedance measurement module 12 in the tester is connected with the fifth electric contact end 301 of the third electrode 23 in the test strip; one end of the second signal switching module 14 in the test meter is grounded, and the other end of the second signal switching module 14 can be connected to the second electrical contact 102 of the first electrode 21 in the test strip or connected to the fourth electrical contact 202 of the second electrode 22 in the test strip.
It can be understood that, with the electrochemical testing device provided in this embodiment, by switching the signals of the first signal switching module 13 and the second signal switching module 14, an electrical loop containing the sample at the sample inlet and an electrical loop containing no sample at the sample inlet can be formed in the test strip. Under the condition, the tester can offset the electrode impedance difference generated by the test strip in the printing process by measuring the impedance value containing the sample inlet electric loop and the impedance value not containing the sample inlet electric loop, so that the test result of the sample analyte concentration is more accurate and reliable.
In a preferred embodiment, the first signal switching module and/or the second signal switching module is/are embodied as a single-pole double-throw switch.
Specifically, in this embodiment, the first signal switching module and/or the second signal switching module are/is configured as a single-pole double-throw switch, because the single-pole double-throw switch is not only common in daily life, but also has a relatively low cost, and thus, the design cost required by the testing apparatus can be relatively reduced by such a configuration.
Referring to fig. 3, fig. 3 is a structural diagram of another electrochemical testing apparatus according to an embodiment of the present invention. As a preferred embodiment, the first impedance measurement module 11 includes: the first DAC, the first ADC, the first operational amplifier U1, the first capacitor C1 and the first resistor R1;
a first input end of the first operational amplifier U1 is connected to the first DAC, a second input end of the first operational amplifier U1 is connected to one end of the first signal switching module K1, a first end of the first capacitor C1, and a first end of the first resistor R1, respectively, and an output end of the first operational amplifier U1 is connected to a second end of the first capacitor C1, a second end of the first resistor R1, and the first ADC, respectively;
accordingly, the second impedance measurement module comprises: the second DAC, the second ADC, the second operational amplifier U2, the second capacitor C2 and the second resistor R2;
a first input end of the second operational amplifier U2 is connected to the second DAC, a second input end of the second operational amplifier U2 is connected to the fifth electrical contact terminal, the first end of the second capacitor C2 and the first end of the second resistor R2, respectively, and an output end of the second operational amplifier is connected to the second end of the second capacitor C2, the second end of the second resistor R2 and the second ADC, respectively.
In this embodiment, a specific arrangement manner of the first impedance measuring module and the second impedance measuring module is provided. It is conceivable that, after a DAC (Digital to Analog Converter) and an ADC (Analog to Digital Converter) are disposed in the first impedance measurement module and the second impedance measurement module, the measurement result of the first impedance measurement module and/or the second impedance measurement module can be more accurate and reliable, so that the accuracy of the sample analyte concentration test result can be further improved.
Based on the above embodiments, this embodiment further describes and optimizes the technical solution, and as a preferred implementation, the above steps: the process of obtaining the impedance value of the electrical circuit containing the sample at the sample inlet in the test strip by using the tester comprises the following steps:
the other end of the first signal switching module is triggered to be connected with the first electric contact end, and the other end of the second signal switching module is connected with the fourth electric contact end to form a first electric loop;
determining a first impedance value of a first electrical circuit in the test strip containing a sample at the sample inlet according to the first electrical circuit;
the other end of the first signal switching module is connected with the third electric contact end, and the other end of the second signal switching module is connected with the second electric contact end to form a second electric loop;
a second impedance value of a second electrical circuit in the test strip containing the sample at the sample inlet is determined from the second electrical circuit.
As a preferred embodiment, the above steps: the process of obtaining the impedance value of the electrical circuit of the test strip not containing the sample at the sample inlet by using the tester comprises the following steps:
the other end of the first signal switching module is triggered to be connected with the first electric contact end, and the other end of the second signal switching module is connected with the second electric contact end to form a third electric loop;
determining a third impedance value of a third electrical circuit in the test strip that does not contain the sample at the sample inlet according to the third electrical circuit;
the other end of the first signal switching module is connected with the third electric contact end, and the other end of the second signal switching module is connected with the fourth electric contact end to form a fourth electric loop;
a fourth impedance value of a fourth electrical circuit in the test strip that does not contain the sample at the sample inlet is determined from the fourth electrical circuit.
In order to make the implementation principle of the present invention more clearly understood by those skilled in the art, the present embodiment is illustrated by a specific application scenario embodiment. Referring to fig. 4, fig. 4 is a schematic diagram of the first electrical circuit. When the other end of the first signal switching module K1 is connected to the first electrical contact terminal and the other end of the second signal switching module K2 is connected to the fourth electrical contact terminal, a first electrical loop containing the sample at the sample inlet, i.e., loop 1, is formed in the test strip.
Referring to fig. 5, fig. 5 is a schematic diagram of the second electrical circuit. When the other end of the first signal switching module K1 is connected to the third electrical contact terminal and the other end of the second signal switching module K2 is connected to the second electrical contact terminal, a second electrical loop containing the sample at the sample inlet, i.e., loop 2, is formed in the test strip.
Referring to fig. 6, fig. 6 is a schematic diagram of a third electrical circuit. In fig. 6, the first signal switching module and the second signal switching module are K1 and K2, respectively. When the other end of the first signal switching module K1 is connected to the first electrical contact terminal and the other end of the second signal switching module K2 is connected to the second electrical contact terminal, a third electrical loop, i.e., loop 3, is formed in the test strip, which does not contain the sample at the sample inlet.
Referring to fig. 7, fig. 7 is a schematic diagram of a fourth electrical circuit. When the other end of the first signal switching module K1 is connected to the third electrical contact terminal and the other end of the second signal switching module K2 is connected to the fourth electrical contact terminal, a fourth electrical loop, i.e., loop 4, is formed in the test strip, which does not contain the sample at the sample inlet.
It can be understood that when the tester obtains the impedance values of the first electrical circuit, the second electrical circuit, the third electrical circuit and the fourth electrical circuit, it is equivalent to obtain two electrical circuits containing samples at the sample inlet of the test strip and two electrical circuits not containing samples at the sample inlet of the test strip, in which case, the tester can use the impedance values of the first electrical circuit, the second electrical circuit, the third electrical circuit and the fourth electrical circuit to offset the impedance values of the electrodes in the test strip.
As a preferred embodiment, the above steps: a process for determining a target impedance value for a sample at a sample inlet using an impedance value of an electrical circuit containing the sample at the sample inlet and an impedance value of an electrical circuit not containing the sample at the sample inlet, comprising:
determining a target impedance value of the sample at the sample inlet by using the first impedance value, the second impedance value, the third impedance value and the fourth impedance value based on the target model;
wherein, the mathematical expression of the target model is as follows:
RHB＝[R01+R02-(R03+R04)]/2；
in the formula, RHBIs a target impedance value, R01Is a first impedance value, R02Is a second impedance value, R03Is a third impedance value, R04Is the fourth impedance value.
Referring to fig. 8, fig. 8 is an electrical equivalent model diagram of the test strip. Wherein the impedance of the electrode in the test strip can be equivalent to a resistance R1、R2、R3、R4And R5The impedance value at the sample inlet of the test strip can be equivalent to RHBThe impedance value at the enzyme region of the test strip drop can be equivalent to Rw. Then, loop 1 is such that it contains R5、R2And RHBI.e. the impedance value of the first electrical circuit is: r03＝R5+R2+RHB(ii) a Loop 2 is a compound containing R4、R2And RHBI.e. the fourth impedance value of the second electrical circuit is: r04＝R4+R1+RHB. Loop 3 is a compound containing R5And R1That is, the impedance value of the third electrical loop is: r01＝R5+R1(ii) a Loop 4 is composed of R4And R2That is, the impedance value of the fourth electrical loop is: r02＝R4+R2。
In summary, the impedance value of the sample at the sample inlet in the test strip is: rHB＝[R03+R04-(R01+R02)]/2. Obviously, the resistance value R of the electrode of the test strip can be eliminated by the test method only by measuring the resistance values of four loops1、R2、R3、R4And R5The influence on the test result of the sample analyte concentration can make the test result of the sample analyte concentration more accurate and reliable.
Referring to fig. 9, fig. 9 is a structural diagram of a testing system of an electrochemical testing apparatus according to an embodiment of the present invention, the testing system is applied to the electrochemical testing apparatus, and the electrochemical testing apparatus includes: the tester comprises a tester and a test strip which is inserted into an interface on the tester and then forms electrical connection with the tester; the test system includes:
the impedance value obtaining module 21 is configured to obtain, by using a tester, an impedance value of an electrical circuit including a sample at the sample inlet and an impedance value of an electrical circuit not including the sample at the sample inlet in the test strip when the analyte concentration of the sample is tested;
a concentration test module 22 for determining a target impedance value of the sample at the sample inlet using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
The test system of the electrochemical test device provided by the embodiment of the invention has the beneficial effects of the test method of the electrochemical test device disclosed in the foregoing.
Referring to fig. 10, fig. 10 is a structural diagram of a testing apparatus of an electrochemical testing device according to an embodiment of the present invention, the testing apparatus including:
a memory 31 for storing a computer program;
a processor 32 for implementing the steps of a method of testing an electrochemical testing device as disclosed above when executing a computer program.
The test system of the electrochemical test device provided by the embodiment of the invention has the beneficial effects of the test method of the electrochemical test device disclosed in the foregoing.
Accordingly, embodiments of the present invention further provide a computer-readable storage medium, on which a computer program is stored, and the computer program, when executed by a processor, implements the steps of the method for testing an electrochemical testing apparatus as disclosed in the foregoing.
The computer-readable storage medium provided by the embodiment of the invention has the beneficial effects of the testing method of the electrochemical testing device disclosed in the foregoing.
The embodiments are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same or similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
Finally, it should also be noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above detailed description of the testing method, system, device and medium of the electrochemical testing apparatus provided by the present invention has been provided, and the principle and the implementation of the present invention are explained by applying specific examples, and the description of the above examples is only used to help understanding the method and the core concept of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present invention.
Claims (10)
1. A method of testing an electrochemical test device, applied to an electrochemical test device, the electrochemical test device comprising: the test strip is inserted into an interface on the tester and then electrically connected with the tester; the test method comprises the following steps:
when the analyte concentration of a sample is tested, acquiring the impedance value of an electric circuit containing the sample at a sample inlet and the impedance value of an electric circuit not containing the sample at the sample inlet in the test strip by using the tester;
determining a target impedance value for the sample at the sample inlet using an impedance value of the electrical circuit containing the sample at the sample inlet and an impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
2. The method of claim 1, wherein the tester comprises: the device comprises a first impedance measuring module, a second impedance measuring module, a first signal switching module and a second signal switching module; the test strip comprises a first electrode, a second electrode and a third electrode, wherein the first electrode, the second electrode and the third electrode are communicated with the sample inlet, the first electrode is provided with a first electric contact end and a second electric contact end, the second electrode is provided with a third electric contact end and a fourth electric contact end, and the third electrode is provided with a fifth electric contact end;
when the test strip is inserted into the interface of the tester, the connection relationship between the test strip and the tester is as follows:
the first impedance measuring module is connected with one end of the first signal switching module, and the other end of the first signal switching module is connected with the first electric contact end or the third electric contact end in a switchable manner;
the second impedance measurement module is connected with the fifth electric contact terminal;
one end of the second signal switching module is grounded, and the other end of the second signal switching module is switchably connected to the second electrical contact end or the fourth electrical contact end.
3. The test method according to claim 2, wherein the first signal switching module and/or the second signal switching module is/are embodied as a single-pole double-throw switch.
4. The testing method of claim 2, wherein the first impedance measurement module comprises: the first DAC, the first ADC, the first operational amplifier, the first capacitor and the first resistor;
a first input end of the first operational amplifier is connected to the first DAC, a second input end of the first operational amplifier is connected to one end of the first signal switching module, a first end of the first capacitor, and a first end of the first resistor, respectively, and an output end of the first operational amplifier is connected to a second end of the first capacitor, a second end of the first resistor, and the first ADC, respectively;
correspondingly, the second impedance measurement module comprises: the second DAC, the second ADC, the second operational amplifier, the second capacitor and the second resistor;
the first input end of the second operational amplifier is connected with the second DAC, the second input end of the second operational amplifier is connected with the fifth electrical contact end, the first end of the second capacitor and the first end of the second resistor respectively, and the output end of the second operational amplifier is connected with the second end of the second capacitor, the second end of the second resistor and the second ADC respectively.
5. The method according to claim 2, wherein the step of obtaining the impedance value of the electrical circuit of the test strip containing the sample at the sample inlet by the tester comprises:
triggering the other end of the first signal switching module to be connected with the first electric contact end, and connecting the other end of the second signal switching module with the fourth electric contact end to form a first electric loop;
determining a first impedance value of the first electrical circuit in the test strip containing the sample at the sample inlet from the first electrical circuit;
triggering the other end of the first signal switching module to be connected with the third electric contact end, and connecting the other end of the second signal switching module with the second electric contact end to form a second electric loop;
determining a second impedance value of the second electrical circuit in the test strip containing the sample at the sample inlet from the second electrical circuit.
6. The method according to claim 5, wherein the step of obtaining the impedance value of the electrical circuit of the test strip not containing the sample at the sample inlet by the tester comprises:
triggering the other end of the first signal switching module to be connected with the first electric contact end, and connecting the other end of the second signal switching module with the second electric contact end to form a third electric loop;
determining from the third electrical circuit a third impedance value of the third electrical circuit in the test strip that does not contain the sample at the sample inlet;
triggering the other end of the first signal switching module to be connected with the third electric contact end, and connecting the other end of the second signal switching module with the fourth electric contact end to form a fourth electric loop;
determining a fourth impedance value of the fourth electrical circuit in the test strip that does not contain the sample at the sample inlet from the fourth electrical circuit.
7. The testing method of claim 6, wherein the determining a target impedance value for the sample at the sample inlet using the impedance value for the electrical circuit containing the sample at the sample inlet and the impedance value for the electrical circuit not containing the sample at the sample inlet comprises:
determining the target impedance value of the sample at the sample inlet using the first impedance value, the second impedance value, the third impedance value, and the fourth impedance value based on a target model;
wherein the mathematical expression of the target model is:
RHB＝[R01+R02-(R03+R04)]/2；
in the formula, RHBIs the target impedance value, R01Is the first impedance value, R02Is the second impedance value, R03Is the third impedance value, R04Is the fourth impedance value.
8. A test system for an electrochemical test device, the test system being applied to an electrochemical test device, the electrochemical test device comprising: the test strip is inserted into an interface on the tester and then electrically connected with the tester; the test system includes:
the impedance value acquisition module is used for acquiring the impedance value of an electric circuit containing the sample at the sample inlet and the impedance value of an electric circuit not containing the sample at the sample inlet in the test strip by using the tester when the analyte concentration of the sample is tested;
a concentration test module for determining a target impedance value of the sample at the sample inlet using the impedance value of the electrical circuit containing the sample at the sample inlet and the impedance value of the electrical circuit not containing the sample at the sample inlet to calculate an analyte concentration of the sample using the target impedance value.
9. A test apparatus for an electrochemical test device, comprising:
a memory for storing a computer program;
a processor for implementing the steps of a method of testing an electrochemical testing device according to any one of claims 1 to 7 when executing said computer program.
10. A computer-readable storage medium, having stored thereon a computer program which, when executed by a processor, carries out the steps of a method of testing an electrochemical testing device according to any one of claims 1 to 7.
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