CN112457971A

CN112457971A - Nucleic acid detector based on closed-loop control system and use method thereof

Info

Publication number: CN112457971A
Application number: CN202011475481.3A
Authority: CN
Inventors: 陆忠秋
Original assignee: Hangzhou Beihua Enterprise Management Co ltd
Current assignee: Hangzhou Huashuo medical laboratory Co.,Ltd.
Priority date: 2020-12-15
Filing date: 2020-12-15
Publication date: 2021-03-09
Anticipated expiration: 2040-12-15
Also published as: CN112457971B

Abstract

The invention discloses a nucleic acid detector based on a closed-loop control system and a using method thereof, and the nucleic acid detector comprises a box body, wherein a working groove with a right opening is arranged in the box body, and slideways with symmetrical front and back positions are fixedly arranged on the bottom wall of the working groove; the cotton swab cutting device is provided with the breaking device, the second rotating shaft is driven to rotate through the driving motor, the pressing rod is driven to rotate through the moving block, the pressing rod drives the cutting head to cut cotton swabs through the control rod, the cotton swabs are cut off to reduce the size, medical staff can store or carry more collected information, the detection efficiency is improved, meanwhile, the medical staff is prevented from contacting the cotton swab head possibly with germs, the identity information of a detected person is read through the information reader, then a label with the identity information of the detected person is printed through the label printer, then the label is pasted outside a test tube through the fan and the arc-shaped block, and the situation that the collected information of the detected person is mistakenly found is avoided.

Description

Nucleic acid detector based on closed-loop control system and use method thereof

Technical Field

The invention relates to the technical field of nucleic acid detection, in particular to a nucleic acid detector based on a closed-loop control system and a using method thereof.

Background

The nucleic acid detecting substance is viral nucleic acid, and is used for searching whether an exogenous invading virus exists in a respiratory tract specimen, blood or feces of a patient to determine whether the patient is infected by the new coronavirus.

The new coronavirus has extremely strong infectivity, so all people in the region and even the whole city need to be checked after a plurality of infected patients appear, the information is collected by penetrating into the nasal cavity through a cotton swab at present, the patient sample is obtained and needs to be detected as soon as possible, the number of the collected samples is large due to the huge number of detected people, one detection mechanism can certainly not detect the samples in time, a plurality of detection mechanisms are required to detect simultaneously, the result can be detected in the shortest time, low-temperature storage is needed in the process of transferring and transporting the collected sample information, the smaller the volume of the sample information is, the larger the number of the collected sample information can be, and more time can be saved.

Disclosure of Invention

The invention aims to provide a nucleic acid detector based on a closed-loop control system and a use method thereof, which are used for overcoming the defects in the prior art.

The nucleic acid detector based on the closed-loop control system comprises a box body, wherein a working groove with a right opening is arranged in the box body, slideways with symmetrical front and back positions are fixedly arranged on the bottom wall of the working groove, an electric sliding rail is arranged on each slideway, a stepping motor is fixedly arranged on the top surface of the electric sliding rail, a driving shaft is arranged on the top surface of the stepping motor, a rotating disc is fixedly arranged on the driving shaft, six annular through grooves which penetrate through the driving shaft up and down are arranged in the rotating disc, a test tube is placed in each through groove, a rubber tube is fixedly arranged on the top surface of the rotating disc at each through groove, an annular groove with a downward opening is arranged on the bottom surface of the rotating disc, supporting rods which are symmetrical left and right and are connected with the annular groove in a sliding manner are fixedly arranged on the electric sliding rail, a deep groove which penetrates through, the power intracavity is equipped with the rupture device that can cut off the cotton stick, it is left to work the groove be equipped with the ascending groove that reads of opening in the box, it has the base to read inslot sliding connection, install information reader in the base top surface, information reader is connected with the plug through the data line, it is equipped with first sliding tray to read wall in-connection about the groove, first sliding tray sliding connection with base fixed connection's connecting block, it is equipped with the intercommunication in the groove right wall to read the spread groove of groove work the groove, it extends to read tank bottom wall mounting label printer in the spread groove, label printer left surface mounting have can with plug connection's socket, install in the spread groove and paste the auxiliary device on test tube surface with the label.

Optionally, the breaking device includes a driving motor fixedly arranged on the rear wall of the power cavity, a first rotating shaft is arranged on the front side surface of the driving motor, a first bevel gear is fixedly arranged at the front end of the first rotating shaft, a second rotating shaft is rotatably connected between the left wall and the right wall of the power cavity, a second bevel gear meshed with the first bevel gear is fixedly arranged on the second rotating shaft, two sections of threads symmetrical to each other in left and right positions are arranged on the second rotating shaft, a moving block is connected to the threads in a threaded manner, a rotating groove penetrating left and right and having a forward opening is arranged in the moving block, a first fixed shaft is fixedly arranged between the upper wall and the lower wall of the rotating groove, a pressing rod is slidably connected in the rotating groove, a second sliding groove penetrating up and down and slidably connected with the first fixed shaft is arranged in the pressing rod, and a second fixed shaft rotatably connected with the pressing rod, go deep into groove left and right wall in-connection and be equipped with the third sliding tray of position symmetry, sliding connection has the cutting head in the third sliding tray, the cutting head lateral surface with the third sliding tray is kept away from through first spring fixed connection between the lateral wall of deep groove, the cutting head lateral surface sets firmly extends to the control lever in the power intracavity, the control lever with press the depression bar to press the pressure to be connected.

Optionally, the auxiliary device comprises an auxiliary block fixedly arranged in the connecting groove, a left-right penetrating processing groove is arranged in the auxiliary block, a label outlet of the label printer extends into the processing groove, a fan is arranged in the rear side surface of the auxiliary block, the fan is provided with a blowing pipe extending into the processing tank, the front wall and the rear wall of the processing tank below the fan are internally communicated with fourth sliding grooves with symmetrical front and rear positions, a fixed block is connected in the fourth sliding groove in a sliding manner, a paper breaking knife is fixedly arranged on the inner side surface of the fixed block, the inner side surface of the fixed block is fixedly connected with the inner wall of the fourth sliding groove through a second spring, install the electro-magnet in the fourth sliding groove wall, the processing tank front side the auxiliary block right flank has set firmly the extension bar, the extension bar right-hand member set firmly can with the arc piece of test tube laminating.

Optionally, the top surface of the box body is rotatably connected with a box cover through a hinge, and a power line is installed on the rear side surface of the box body.

Optionally, an infrared sensor is installed in the left wall of the electric sliding rail.

A method for using a nucleic acid detector based on a closed-loop control system comprises the following specific steps:

firstly, an electric slide rail is started to move rightwards, so that a rotating disc moves rightwards, medical staff can place empty test tubes into a through groove, then the electric slide rail is started to drive the rotating disc to move leftwards, the leftmost test tube is positioned below a deep groove, then a plug is inserted into a socket, a base is slidably mounted in a reading groove, and preparation work is completed;

secondly, medical personnel put the ID card of the detected person on an information reader, the information reader transmits information to a label printer through a data line, the label printer prints the identity information of the detected person into a label, meanwhile, the medical personnel deepens the cotton swab collecting the information into a deep groove, an infrared sensor detects that the cotton swab is deep and then starts a driving motor, the driving motor drives a first bevel gear to rotate through a first rotating shaft after being started, the first bevel gear drives a second rotating shaft to rotate through a second bevel gear, threads on the second rotating shaft also rotate, a movable block moves towards the direction far away from the second bevel gear along with the rotation of the threads, the movable block drives a pressing rod to rotate around a second fixed shaft through the first fixed shaft, the front end of the pressing rod can press the control rod to drive the control rod to move towards the direction near the deep groove, the control rod drives a cutting head to move towards the deep groove to cut off the cotton swab in the deep groove, then the driving motor rotates reversely to reset the pressing rod, and the cutting head moves towards the third sliding groove to reset under the action of the first spring;

the third step, the cotton swab head after the fracture drops to the test tube in, label printer stretches out the label back through a lot of sign mouth to the work inslot this moment, then the fan starts to blow through the blowing pipe to the processing inslot and make label front end and arc piece laminating forward with the label, then step motor starts, drive the rolling disc and rotate next empty test tube and to deepening the groove below, then the test tube that is equipped with the cotton swab head rotates and makes the label paste on the test tube with the arc piece laminating, the electro-magnet stops work fixed block and removes the label to the processing inslot under the second spring action and cut after that, accomplish the work of pasting of label.

The invention has the beneficial effects that:

firstly, the cotton swab cutting device is provided with a breaking device, a second rotating shaft is driven to rotate through a driving motor, so that a pressing rod is driven to rotate through a moving block, the pressing rod drives a cutting head to cut cotton swabs through a control rod, the cotton swabs are cut off, the size of the cotton swabs is reduced, medical staff can store or carry more acquisition information, the detection efficiency is improved, and meanwhile, the medical staff is prevented from contacting the cotton swab heads possibly with germs;

secondly, the identity information of the detected person is read by the information reader, then the label with the identity information of the detected person is printed by the label printer, and the label is attached to the outside of the test tube by the fan and the arc-shaped block.

Thirdly, the rotation of the rotating disc is subjected to negative feedback regulation through the stepping motor, so that the rotating disc is a closed-loop control system, and the stepping motor can offset the angle generated during each rotation, so that the alignment of the test tube opening and the deep groove can be ensured, and the swab head can accurately enter the test tube.

Drawings

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.

FIG. 1 is a schematic diagram of a nucleic acid detecting apparatus based on a closed loop control system according to the present invention;

FIG. 2 is a schematic view of the structure at C-C in FIG. 1;

FIG. 3 is a schematic view of the fracturing apparatus of FIG. 1;

FIG. 4 is a schematic view of the structure at B-B in FIG. 3;

FIG. 5 is a schematic view of the structure at A-A in FIG. 1;

FIG. 6 is a schematic view of the structure at the connecting slot in FIG. 5;

fig. 7 is a schematic view of the structure at D-D in fig. 6.

Detailed Description

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

Referring to fig. 1-7, a nucleic acid detecting apparatus based on a closed-loop control system according to an embodiment of the present invention includes a case 32, a working groove 31 with a right opening is provided in the case 32, slideways 27 with symmetrical front and back positions are fixedly provided on the bottom wall of the working groove 31, an electric sliding rail 25 is provided on the slideways 27, a stepping motor 26 is fixedly provided on the top surface of the electric sliding rail 25, a driving shaft 28 is provided on the top surface of the stepping motor 26, a rotating disc 30 is fixedly provided on the driving shaft 28, six annular through grooves 70 penetrating up and down are provided in the rotating disc 30, test tubes 23 are disposed in the through grooves 70, a rubber tube 54 is fixedly provided on the top surface of the rotating disc 30 at the through grooves 70, an annular groove 29 with a downward opening is provided on the bottom surface of the rotating disc 30, support rods 24 which are symmetrically left and right and slidably connected to, a deep groove 35 penetrating through the top surface of the box body 32 is arranged in the top wall of the working groove 31 in a communicating manner, a power cavity 37 is arranged behind the deep groove 35, a breaking device 101 capable of cutting off a cotton swab is arranged in the power cavity 37, a reading groove 17 with an upward opening is arranged in the box body 32 on the left side of the working groove 31, a base 16 is connected in the reading groove 17 in a sliding manner, an information reader 15 is arranged in the top surface of the base 16, the information reader 15 is connected with a plug 19 through a data line 18, a first sliding groove 13 is arranged in the left wall and the right wall of the reading groove 17 in a communicating manner, a connecting block 14 fixedly connected with the base 16 is connected in the first sliding groove 13 in a sliding manner, a connecting groove 22 communicated with the working groove 31 is arranged in the right wall of the reading groove 17, a label printer 21 extending into the connecting groove 22 is arranged on the bottom wall of the reading groove 17, and a socket 20, an auxiliary device 102 capable of adhering a label on the surface of the test tube is installed in the connecting groove 22.

Preferably, the breaking device 101 includes a driving motor 50 fixedly disposed on the rear wall of the power cavity 37, a first rotating shaft 51 is mounted on the front side surface of the driving motor 50, a first bevel gear 52 is fixedly disposed at the front end of the first rotating shaft 51, a second rotating shaft 39 is rotatably connected between the left and right walls of the power cavity 37, a second bevel gear 53 engaged with the first bevel gear 52 is fixedly disposed on the second rotating shaft 39, two sections of threads 45 symmetrical to each other in left and right positions are disposed on the second rotating shaft 39, a moving block 46 is connected to the threads 45 by threads, a rotating groove 47 penetrating left and right and opening forward is disposed in the moving block 46, a first fixed shaft 49 is fixedly disposed between the upper and lower walls of the rotating groove 47, a pressing rod 40 is slidably connected in the rotating groove 47, and a second sliding groove 48 penetrating up and down and slidably connected with the first fixed shaft 49 is disposed in the pressing rod 40, fixedly connected with between the upper and lower wall of power chamber 37 with press the second fixed axle 38 that 40 rotations of depression bar are connected, deep groove 35 left and right wall in-connection is equipped with the third sliding tray 43 of position symmetry, sliding connection has cutting head 44 in the third sliding tray 43, cutting head 44 lateral surface with third sliding tray 43 is kept away from through first spring 42 fixed connection between the lateral wall of deep groove 35, cutting head 44 lateral surface sets firmly and extends to control lever 41 in the power chamber 37, control lever 41 with press the depression bar 40 to support the pressure to be connected, can cut off the cotton swab and reduce the volume for medical personnel can store or carry more information acquisition, improve detection efficiency.

Preferably, the auxiliary device 102 includes an auxiliary block 56 fixedly arranged in the connecting groove 22, a processing groove 59 penetrating left and right is arranged in the auxiliary block 56, the label outlet 55 of the label printer 21 extends into the processing groove 59, a blower 57 is arranged in the rear side surface of the auxiliary block 56, a blowing pipe 58 extending into the processing groove 59 is arranged on the blower 57, a fourth sliding groove 64 symmetrical in front and back is arranged in the front and back wall of the processing groove 59 below the blower 57, a fixing block 63 is connected in the fourth sliding groove 64 in a sliding manner, a paper breaking knife 62 is fixedly arranged on the inner side surface of the fixing block 63, the inner side surface of the fixing block 63 is fixedly connected with the inner wall of the fourth sliding groove 64 through a second spring 65, an electromagnet 66 is arranged in the wall of the fourth sliding groove 64, an extending rod 60 is fixedly arranged on the right side surface of the auxiliary block 56 at the front side of the processing groove 59, the extension bar 60 right-hand member set firmly can with the arc piece 61 of test tube 23 laminating, can pass through the label with the person information of detecting automatically and paste the test tube 23 outer wall that is equipped with the label head that corresponds.

Preferably, the top surface of the box body 32 is rotatably connected with the box cover 11 through a hinge 33, and the rear side surface of the box body 32 is provided with a power cord 34.

Preferably, an infrared sensor 36 is installed in the left wall of the electric slide rail 25, and the infrared sensor 36 can detect penetration of a cotton swab.

firstly, the electric slide rail 25 is started to move rightwards, so that the rotating disc 30 moves rightwards, the medical staff can put the empty test tube 23 into the through groove 70, then the electric slide rail 25 is started to drive the rotating disc 30 to move leftwards, the leftmost test tube 23 is positioned below the deep groove 35, then the plug 19 is inserted into the socket 20, and the base 16 is slidably installed in the reading groove 17, so that the preparation work is completed;

secondly, the medical staff places the identity card of the detected person on the information reader 15, the information reader 15 transmits the information to the label printer 21 through the data line 18, the label printer 21 prints the identity information of the detected person into a label, meanwhile, the medical staff puts the cotton swab with the collected information deep into the deep groove 35, the infrared sensor 36 detects that the cotton swab is deep and then starts the driving motor 50, the driving motor 50 starts the driving motor and drives the first bevel gear 52 to rotate through the first rotating shaft 51, the first bevel gear 52 drives the second rotating shaft 39 to rotate through the second bevel gear 53, the thread 45 on the second rotating shaft 39 also rotates, the moving block 46 moves away from the second bevel gear 53 along with the rotation of the thread 45, the moving block 46 drives the pressing rod 40 to rotate around the second fixing shaft 38 through the first fixing shaft 49, the front end of the pressing rod 40 can press the control rod 41, the control rod 41 is driven to move towards the direction close to the deep groove 35, the control rod 41 drives the cutting head 44 to move towards the deep groove 35 to cut off the cotton swab in the deep groove 35, then the driving motor 50 rotates reversely to reset the pressing rod 40, and then the cutting head 44 moves towards the third sliding groove 43 to reset under the action of the first spring 42;

thirdly, the broken cotton swab head falls into the test tube 23, the label printer 21 sends out the label and then stretches out the label into the working groove 31 through the label outlet 55, then the fan 57 starts to blow the label forward into the processing groove 59 through the blowing pipe 58 so that the front end of the label is attached to the arc-shaped block 61, then the stepping motor 26 starts to drive the rotating disc 30 to rotate the next empty test tube 23 to the position deep below the groove 35, then the test tube 23 with the cotton swab head is rotated to be attached to the arc-shaped block 61 so that the label is attached to the test tube 23, then the electromagnet 66 stops working the fixing block 63 to move in the processing groove 59 under the action of the second spring 65 to cut the label, and label attaching work is completed.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. A nucleic acid detector based on a closed-loop control system comprises a box body, and is characterized in that: the cotton swab box is characterized in that a working groove with a right opening is formed in the box body, slideways with symmetrical front and back positions are fixedly arranged on the bottom wall of the working groove, an electric sliding rail is mounted on each slideway, a stepping motor is fixedly arranged on the top surface of each electric sliding rail, a driving shaft is mounted on the top surface of each stepping motor, a rotating disc is fixedly arranged on each driving shaft, six annular through grooves which penetrate through the through grooves from top to bottom are formed in each rotating disc, a rubber tube is fixedly arranged at the position, corresponding to each through groove, of the top surface of each rotating disc, a circular groove with a downward opening is formed in the bottom surface of each rotating disc, supporting rods which are symmetrical left and right and are in sliding connection with the circular grooves are fixedly arranged on the electric sliding rails, a deep groove penetrating through the top surface of the box body is formed in the top, work the groove left be equipped with the ascending groove of reading of opening in the box, it has the base to read inslot sliding connection, install information reading device in the base top surface, information reading device is connected with the plug through the data line, it is equipped with first sliding tray to read wall in-connection about the groove, first sliding tray sliding connection have with base fixed connection's connecting block, it is equipped with the intercommunication in the wall to read groove right side work the spread groove of groove, it extends to read tank bottom wall mounting label printer in the spread groove, label printer left surface mounting have can with plug connection's socket, install the auxiliary device that can paste the label on the test tube surface in the spread groove.

2. The nucleic acid detecting instrument based on the closed-loop control system as claimed in claim 1, wherein: the breaking device comprises a driving motor fixedly arranged on the rear wall of the power cavity, a first rotating shaft is arranged on the front side surface of the driving motor, a first bevel gear is fixedly arranged at the front end of the first rotating shaft, a second rotating shaft is rotatably connected between the left wall and the right wall of the power cavity, a second bevel gear meshed with the first bevel gear is fixedly arranged on the second rotating shaft, two sections of threads which are symmetrical in left and right positions are arranged on the second rotating shaft, a moving block is connected to the threads in a threaded manner, a rotating groove which penetrates left and right and is provided with a forward opening is formed in the moving block, a first fixed shaft is fixedly arranged between the upper wall and the lower wall of the rotating groove, a pressing rod is connected in the rotating groove in a sliding manner, a second sliding groove which penetrates up and down and is connected with the first fixed shaft in a sliding manner is formed in the pressing rod, and, go deep into groove left and right wall in-connection and be equipped with the third sliding tray of position symmetry, sliding connection has the cutting head in the third sliding tray, the cutting head lateral surface with the third sliding tray is kept away from through first spring fixed connection between the lateral wall of deep groove, the cutting head lateral surface sets firmly extends to the control lever in the power intracavity, the control lever with press the depression bar to press the pressure to be connected.

3. The nucleic acid detecting instrument based on the closed-loop control system as claimed in claim 1, wherein: the auxiliary device comprises an auxiliary block fixedly arranged in the connecting groove, a processing groove which penetrates through the auxiliary block from left to right is arranged in the auxiliary block, a label outlet of the label printer extends into the processing groove, a fan is arranged in the rear side surface of the auxiliary block, the fan is provided with a blowing pipe extending into the processing tank, the front wall and the rear wall of the processing tank below the fan are internally communicated with fourth sliding grooves with symmetrical front and rear positions, a fixed block is connected in the fourth sliding groove in a sliding manner, a paper breaking knife is fixedly arranged on the inner side surface of the fixed block, the inner side surface of the fixed block is fixedly connected with the inner wall of the fourth sliding groove through a second spring, install the electro-magnet in the fourth sliding groove wall, the processing tank front side the auxiliary block right flank has set firmly the extension bar, the extension bar right-hand member set firmly can with the arc piece of test tube laminating.

4. The nucleic acid detecting instrument based on the closed-loop control system as claimed in claim 1, wherein: the box top surface is connected with the case lid through hinge rotation, the box trailing flank installs the power cord.

5. The nucleic acid detecting instrument based on the closed-loop control system as claimed in claim 1, wherein: and an infrared sensor is arranged in the left wall of the electric sliding rail.

6. A use method of a nucleic acid detector based on a closed-loop control system is characterized by comprising the following specific steps: