CN112451850A - Iodine-125 particle is with implanting device - Google Patents

Iodine-125 particle is with implanting device Download PDF

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Publication number
CN112451850A
CN112451850A CN202011448693.2A CN202011448693A CN112451850A CN 112451850 A CN112451850 A CN 112451850A CN 202011448693 A CN202011448693 A CN 202011448693A CN 112451850 A CN112451850 A CN 112451850A
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particle
pipe
tube
implantation
particles
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CN112451850B (en
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王姗姗
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1009Apparatus for loading seeds into magazines or needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1011Apparatus for permanent insertion of sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention relates to the technical field of medical instruments, in particular to an implantation device for iodine-125 particles, which comprises a particle implantation tube, wherein one end of the particle implantation tube is provided with a conical part, the other end of the particle implantation tube is provided with a particle delivery tube which is detachably connected, a plurality of particle storage chambers are arranged inside the particle implantation tube, a plurality of detachable particle storage components are arranged inside the particle delivery tube, the particle storage components are matched with the particle storage chambers, a detachable pushing component is arranged on the particle delivery tube, and the particle storage components enter the particle storage chambers through the pushing component.

Description

Iodine-125 particle is with implanting device
Technical Field
The invention relates to the technical field of medical instruments, in particular to an implantation device for iodine-125 particles.
Background
The radioactive particle implantation treatment technology is called particle implantation for short, and is a treatment method for implanting radioactive source into the interior of tumor to make it destroy tumor. The seed implantation treatment technology relates to a radioactive source, and the core of the seed implantation treatment technology is a radioactive seed. The radioactive particle implantation treatment technology mainly depends on a stereotactic system to accurately implant radioactive particles into a tumor body, and a micro radioactive source emits continuous and short-distance radioactive rays to kill tumor tissues to the maximum extent, while normal tissues are not damaged or only slightly damaged.
The iodine-125 particles are radioactive isotopes with the half-life of 59.6 days, and iodine-125 sealed seed sources prepared from the iodine-125 particles are widely applied to brachytherapy of solid tumors such as lung cancer, prostatic cancer, pancreatic cancer and the like. In recent years, iodide ions have been used for malignant obstruction of hollow organs such as biliary tract, esophagus, portal vein, vena cava, and ureter. At present, in the prior art, iodine-125 particles or particle strips are fixed on a cylindrical mesh support outside a human body in a binding, sewing, bonding and other modes, and then the mesh support is implanted to the obstruction part of a human body lumen channel through a related device, but the operation is difficult, the particle strips are not easy to accurately position, and the pain of a patient can be increased in clinical operation. In order to solve the above problems, the prior art discloses an implantation device comprising an ion storage tube, a delivery catheter, a guide wire and a separation guide wire, wherein in practical application, a puncture needle is used for puncturing into a human body lumen through skin, then a catheter sheath is introduced, the guide wire passes through the obstruction of the human body lumen, the particle storage tube and the delivery catheter are implanted into the human body lumen along the guide wire, and the particles are delivered to the obstruction of the human body lumen through the separation guide wire and the delivery catheter. Although the implantation device solves the problems of inconvenience and difficulty in accurate positioning of the implanted particles to a certain extent, when the implantation device adopting the structure is used for implanting the particles, a plurality of iodine-125 particles are required to be respectively placed into the particle conveying pipe firstly, and then the particles are pushed to the particle storage pipe through the separation guide wire, so that the time for implanting the particles is long, the implanted iodine-125 particles are not uniformly distributed, and the treatment effect is finally influenced; furthermore, if radiotherapy is needed again, the implant device and the particles can only be taken out together, and the puncture needle is used for puncturing and the catheter sheath is introduced again for re-implantation, which undoubtedly increases the pain of the patient. Therefore, in order to solve the above problems, it is necessary to develop an implantation device for iodine-125 particles.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: aiming at the defects of the prior art, the implantation device for the iodine-125 particles is provided, the implantation device is short in iodine-125 particle implantation time and convenient to operate, and can ensure that the iodine-125 particles are uniformly distributed.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the utility model provides an iodine-125 is implantation device for particle, includes the particle implantation pipe, the one end of particle implantation pipe is equipped with the toper portion, the other end of particle implantation pipe is equipped with the particle conveyer pipe that can dismantle the connection, the inside of particle implantation pipe is equipped with a plurality of particle apothecas, the inside of particle conveyer pipe is equipped with a plurality of detachable particle storage components, particle storage component with particle apotheca looks adaptation, be equipped with detachable pushing means on the particle conveyer pipe, particle storage component passes through pushing means gets into the particle apotheca.
As an improved technical solution, the particle storage component is a particle storage tube, the particle storage tube includes a tube body, two ends of the tube body are closed, a tube cover is disposed on the top of the tube body, a plurality of partition plates are disposed inside the tube body, and a particle placement area is disposed between two adjacent partition plates.
As an improved technical scheme, a plurality of containing chambers are arranged inside the particle conveying pipe, the particle storage pipe is located inside the containing chambers and is in sliding connection with the containing chambers, a sliding block is arranged on the outer wall of the pipe body of the particle storage pipe, and a sliding groove matched with the sliding block is arranged on the inner wall of the containing chambers.
As an improved technical scheme, the pushing component is a telescopic push rod arranged at the center of the particle conveying pipe, and a handle is arranged at the end part of the telescopic push rod.
As an improved technical scheme, the telescopic push rod is connected with the particle conveying pipe or the particle storage pipe in a clamping manner.
As an improved technical scheme, a clamping groove matched with the telescopic push rod is respectively arranged at the center of the particle conveying pipe or at one end of the pipe body of the particle storage pipe.
As an improved technical scheme, a clamping column is arranged at one end, close to the conical part of the particle storage tube and the particle implantation tube, and a clamping groove matched with the clamping column is arranged on the particle storage chamber.
After the technical scheme is adopted, the invention has the beneficial effects that:
because iodine-125 is implantation device for particle, including the particle implantation pipe, the one end of particle implantation pipe is equipped with the toper portion, and the other end of particle implantation pipe is equipped with the particle conveyer pipe that can dismantle the connection, and the inside of particle implantation pipe is equipped with a plurality of particle apothecas, and the inside of particle conveyer pipe is equipped with a plurality of detachable particle storage components, and particle storage component and particle apotheca looks adaptation are equipped with detachable push unit on the particle conveyer pipe, and particle storage component gets into the particle apotheca through push unit. In practical application, a human body duct is punctured by a puncture needle in a percutaneous mode, a duct sheath with required specifications is introduced according to actual requirements, the assembly body of the conveying duct and the implantation duct is pushed by the pushing part, so that the particle implantation duct enters the obstruction position of the human body duct cavity, the particle storage part filled with iodine 125 particles in the particle conveying pipe is sequentially pushed into the particle storage chamber of the implantation duct by the pushing part, and then the conveying duct and the pushing part are moved out. Before the implantation device is used for implanting the radioactive seeds, medical staff firstly load the iodine-125 particles into the particle storage part, then respectively place the particle storage part in the particle delivery pipe, and then push the particle storage part loaded with the iodine-125 particles into the particle storage chamber of the implantation catheter through the pushing part, so that the time for implanting the particles is short, the particles are accurately positioned, the implanted iodine-125 particles are uniformly distributed, and the treatment effect on the affected part is further improved; in addition, when radiotherapy is needed again, only the particle storage component in the particle implantation catheter needs to be taken out, and then the new particle storage component filled with particles is pushed to the particle storage chamber of the particle implantation catheter, so that the pain of a patient caused by re-implantation is effectively relieved.
Because particle storage unit is the particle storage tube, and the particle storage tube includes the body, and the both ends of body are sealed, and the top of body is equipped with the tube cap, and the inside of body is equipped with a plurality of baffles, places the district for the particle between two adjacent baffles.
Because the particle conveying pipe is internally provided with a plurality of containing chambers, the particle storage pipe is positioned in the containing chambers and is in sliding connection with the containing chambers, the outer wall of the pipe body of the particle storage pipe is provided with a sliding block, and the inner wall of the containing chambers is provided with a sliding chute matched with the sliding block. The particle storage component filled with the iodine-125 particles is connected with the containing chamber in a sliding way through the sliding block, and the design is convenient for pushing the storage component filled with the radioactive particles to the inside of the particle storage chamber.
The pushing component is a telescopic push rod arranged at the center of the particle conveying pipe, and the end part of the telescopic push rod is provided with a handle. In practical application, the medical personnel who do the operation hold the handle and be used for promoting telescopic push rod, implant the assembly body of pipe and conveying pipe, when implanting the pipe and reach the intestinal stalk department of human body lumen way, take off telescopic push rod after and the one end card of particle storage part is fixed together, promote telescopic push rod hard, utilize telescopic push rod with the particle storage part propelling movement to implant in the particle storage chamber of pipe.
The center of the particle conveying pipe or one end of the pipe body of the particle storage pipe is respectively provided with a clamping groove matched with the telescopic push rod. In practical application, one end of the telescopic push rod is inserted into the clamping groove, and the telescopic push rod is pushed to push the particle conveying pipe and the particle implantation pipe assembly body and push the particle storage component.
Because the particle storage tube is provided with a clamping column at one end close to the conical part of the particle implantation tube, the particle storage chamber is provided with a clamping groove matched with the clamping column. In practical application, after the telescopic push rod pushes the particle storage tube to the particle storage chamber, the clamping column at one end of the particle storage tube is inserted into the clamping groove to fix the particle storage tube. The particle storage tube is reasonable in design, and the particle storage tube is fixed.
Drawings
FIG. 1 is a schematic structural view of an implanting device for iodine-125 particles according to the present invention;
FIG. 2 is a schematic view of the structure of the particle implantation tube of FIG. 1;
FIG. 3 is a schematic view of the particle transporting tube shown in FIG. 1;
FIG. 4 is a schematic view of the particle storage component of FIG. 1;
FIG. 5 is a structural view of the pushing member of FIG. 1;
the particle implantation device comprises a particle implantation tube 1, a conical part 10, a particle storage chamber 11, a clamping groove 110, a particle delivery tube 2, a particle storage chamber 20, a sliding groove 200, a clamping groove 21, a particle storage component 3, a tube body 30, a partition plate 300, a particle placement area 301, a sliding block 302, a clamping column 303, a clamping groove 304, a tube cover 31, a pushing component 4, a handle 40, a first push rod 41 and a second push rod 42.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail below with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
An implantation device for iodine-125 particles, as shown in fig. 1 and fig. 5, comprises a particle implantation tube 1, wherein one end of the particle implantation tube 1 is provided with a taper part 10, the other end of the particle implantation tube 1 is provided with a particle delivery tube 2 which can be detachably connected (the particle delivery tube and the particle delivery tube are fixedly connected in a clamping manner), a plurality of particle storage chambers 11 are arranged inside the particle implantation tube 1, a plurality of detachable particle storage components 3 are arranged inside the particle delivery tube 2, the particle storage components 3 are matched with the particle storage chambers 11, a detachable pushing component 4 is arranged on the particle delivery tube 2, and the particle storage components 3 enter the particle storage chambers 11 through the pushing component 4.
In practical application, a human body duct is punctured by a puncture needle in a percutaneous mode, a duct sheath with required specifications is introduced according to actual requirements, the assembly body of the conveying duct and the implantation duct is pushed by the pushing part, so that the particle implantation duct enters the obstruction position of the human body duct cavity, the particle storage part filled with iodine 125 particles in the particle conveying pipe is sequentially pushed into the particle storage chamber of the implantation duct by the pushing part, and then the conveying duct and the pushing part are moved out. Before the implantation device is used for implanting the radioactive seeds, medical staff firstly load the iodine-125 particles into the particle storage part, then respectively place the particle storage part in the particle delivery pipe, and then push the particle storage part loaded with the iodine-125 particles into the particle storage chamber of the implantation catheter through the pushing part, so that the time for implanting the particles is short, the particles are accurately positioned, the implanted iodine-125 particles are uniformly distributed, and the treatment effect on the affected part is further improved; in addition, when the radiotherapy is needed to be performed again, the particle conveying pipe and the particle implantation pipe are assembled together, the particle storage component in the particle implantation catheter is taken out by the pushing component, and then the new particle storage component filled with the particles is pushed to the particle storage chamber of the particle implantation catheter.
As shown in fig. 4, the particle storage component 3 is a particle storage tube, the particle storage tube includes a tube body 30, two ends of the tube body are sealed, a tube cover 31 is disposed on the top of the tube body 30 (one side of the tube cover is hinged to the tube body, and the other side of the tube cover is fastened to the tube body), a plurality of partition boards 300 are disposed inside the tube body 30, and a particle placement area 301 is disposed between two adjacent partition boards.
As shown in fig. 3, a plurality of receiving chambers 20 are disposed inside the particle transporting tube 2, the particle storage tube 3 is disposed inside the receiving chambers 20 and slidably connected to the receiving chambers 20, wherein a sliding block 302 is disposed on an outer wall of a tube body of the particle storage tube 3, and a sliding groove 200 adapted to the sliding block is disposed on an inner wall of the receiving chamber 20. The particle storage component filled with the iodine-125 particles is connected with the containing chamber in a sliding way through the sliding block, and the design is convenient for pushing the storage component filled with the radioactive particles to the inside of the particle storage chamber.
As shown in fig. 5, the pushing member 4 is a telescopic rod (including a first pushing rod 41 and a second pushing rod 42 connected by a screw thread) disposed at the center of the particle transporting tube, and a handle 40 is disposed at an end of the telescopic rod. In practical application, the medical personnel who do the operation hold the handle and be used for promoting telescopic push rod, implant the assembly body of pipe and conveying pipe, when implanting the pipe and reach the intestinal stalk department of human body lumen way, take off telescopic push rod after and the one end card of particle storage part is fixed together, promote telescopic push rod hard, utilize telescopic push rod with the particle storage part propelling movement to implant in the particle storage chamber of pipe.
Wherein the center of the particle conveying pipe 2 is provided with a clamping groove 21 matched with the telescopic push rod. In practical application, one end of the telescopic push rod is inserted into the clamping groove, and the telescopic push rod is pushed to push the particle conveying pipe and the particle implantation pipe assembly body and push the particle storage component.
One end of the particle storage tube 3 is provided with a clamping groove 304 matched with the telescopic push rod, one end of the particle storage tube 3 close to the conical part of the particle implantation tube 2 is provided with a clamping column 303, and the particle storage chamber 11 is provided with a clamping groove 110 matched with the clamping column 303. In practical application, after the telescopic push rod pushes the particle storage tube to the particle storage chamber, the clamping column at one end of the particle storage tube is inserted into the clamping groove to fix the particle storage tube.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (7)

1. An implanting device for iodine-125 particles, comprising: including the particle implantation pipe, the one end of particle implantation pipe is equipped with the toper portion, the other end of particle implantation pipe is equipped with the particle conveyer pipe that can dismantle the connection, the inside of particle implantation pipe is equipped with a plurality of particle apothecas, the inside of particle conveyer pipe is equipped with a plurality of detachable particle storage parts, particle storage part with particle apotheca looks adaptation, be equipped with detachable promotion part on the particle conveyer pipe, particle storage part passes through promotion part gets into the particle apotheca.
2. An implanting device for iodine-125 particles as set forth in claim 1, wherein: the particle storage component is a particle storage tube, the particle storage tube comprises a tube body, two ends of the tube body are sealed, a tube cover is arranged at the top of the tube body, a plurality of partition plates are arranged inside the tube body, and a particle placing area is arranged between every two adjacent partition plates.
3. An implanting device for iodine-125 particles as set forth in claim 1, wherein: the particle conveying pipe is internally provided with a plurality of containing chambers, the particle storage pipe is positioned in the containing chambers and is in sliding connection with the containing chambers, the outer wall of the pipe body of the particle storage pipe is provided with a sliding block, and the inner wall of each containing chamber is provided with a sliding groove matched with the sliding block.
4. An implanting device for iodine-125 particles as set forth in claim 1, wherein: the pushing component is a telescopic push rod arranged at the center of the particle conveying pipe, and a handle is arranged at the end part of the telescopic push rod.
5. The implanting device for iodine-125 particles as set forth in claim 4, wherein: the telescopic push rod is connected with the particle conveying pipe or the particle storage pipe in a clamping manner.
6. An implanting device for iodine-125 particles as set forth in claim 4 or 5, wherein: the center of the particle conveying pipe or one end of the pipe body of the particle storage pipe is respectively provided with a clamping groove matched with the telescopic push rod.
7. An implanting device for iodine-125 particles as set forth in claim 1, wherein: the particle storage chamber is provided with a particle implantation tube, the particle implantation tube is arranged in the particle storage chamber, and the particle implantation tube is provided with a particle implantation tube.
CN202011448693.2A 2020-12-11 2020-12-11 Iodine-125 is implantation device for particle Active CN112451850B (en)

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Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244132A (en) * 1996-12-02 2000-02-09 Delab公司 Device for local administration of solid and semisolid pharmaceutical for mulations, sustained-release pharmaceutical formulations for parenteral administration and method of preparation
US6200258B1 (en) * 1999-08-10 2001-03-13 Syntheon, Llc Radioactive therapeutic seed having selective marker configuration
US20020077522A1 (en) * 2000-12-15 2002-06-20 Kawasumi Laboratories, Inc. Protective tool for therapeutic material delivery device, cartridge for therapeutic material delivery device, and a therapeutic material delivery device
US20040230087A1 (en) * 2003-05-13 2004-11-18 Terwilliger Richard A. Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
CN202569187U (en) * 2012-05-04 2012-12-05 中国人民解放军第四军医大学 Endoscopic puncture and active particle implantation device
CN103877675A (en) * 2014-02-21 2014-06-25 牛洪欣 Intracavity radioactive-particle implant
CN204582289U (en) * 2015-04-29 2015-08-26 云南省第一人民医院 A kind of biliary tract continues radiotherapy unit
CN105188845A (en) * 2013-03-14 2015-12-23 C·R·巴德股份有限公司 Brachytherapy seed insertion and fixation system
CN105727432A (en) * 2016-04-19 2016-07-06 牛洪欣 Recyclable conformal radioactive particle cabin
CN206007666U (en) * 2016-05-12 2017-03-15 赵兴康 A kind of biliary drainage device of new implantation compound particle bar
CN108525142A (en) * 2018-04-19 2018-09-14 李智 A kind of I-125 seeds implanted device and apply its method for implantation
CN207980169U (en) * 2017-08-22 2018-10-19 曲靖市第二人民医院 A kind of continuous radioactivity125I particle chains
CN208405752U (en) * 2017-12-14 2019-01-22 王姗姗 A kind of cancer of pancreas radiotherapy implantation catheter
CN211271034U (en) * 2019-10-23 2020-08-18 常伟 Self-locking pen type universal particle implantation equipment
CN211355762U (en) * 2019-06-13 2020-08-28 徐勤义 Detachable lumbar puncture needle

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244132A (en) * 1996-12-02 2000-02-09 Delab公司 Device for local administration of solid and semisolid pharmaceutical for mulations, sustained-release pharmaceutical formulations for parenteral administration and method of preparation
US6200258B1 (en) * 1999-08-10 2001-03-13 Syntheon, Llc Radioactive therapeutic seed having selective marker configuration
US20020077522A1 (en) * 2000-12-15 2002-06-20 Kawasumi Laboratories, Inc. Protective tool for therapeutic material delivery device, cartridge for therapeutic material delivery device, and a therapeutic material delivery device
US20040230087A1 (en) * 2003-05-13 2004-11-18 Terwilliger Richard A. Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
CN202569187U (en) * 2012-05-04 2012-12-05 中国人民解放军第四军医大学 Endoscopic puncture and active particle implantation device
CN105188845A (en) * 2013-03-14 2015-12-23 C·R·巴德股份有限公司 Brachytherapy seed insertion and fixation system
CN103877675A (en) * 2014-02-21 2014-06-25 牛洪欣 Intracavity radioactive-particle implant
CN204582289U (en) * 2015-04-29 2015-08-26 云南省第一人民医院 A kind of biliary tract continues radiotherapy unit
CN105727432A (en) * 2016-04-19 2016-07-06 牛洪欣 Recyclable conformal radioactive particle cabin
CN206007666U (en) * 2016-05-12 2017-03-15 赵兴康 A kind of biliary drainage device of new implantation compound particle bar
CN207980169U (en) * 2017-08-22 2018-10-19 曲靖市第二人民医院 A kind of continuous radioactivity125I particle chains
CN208405752U (en) * 2017-12-14 2019-01-22 王姗姗 A kind of cancer of pancreas radiotherapy implantation catheter
CN108525142A (en) * 2018-04-19 2018-09-14 李智 A kind of I-125 seeds implanted device and apply its method for implantation
CN211355762U (en) * 2019-06-13 2020-08-28 徐勤义 Detachable lumbar puncture needle
CN211271034U (en) * 2019-10-23 2020-08-18 常伟 Self-locking pen type universal particle implantation equipment

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