CN105727432A - Recyclable conformal radioactive particle cabin - Google Patents
Recyclable conformal radioactive particle cabin Download PDFInfo
- Publication number
- CN105727432A CN105727432A CN201610240632.4A CN201610240632A CN105727432A CN 105727432 A CN105727432 A CN 105727432A CN 201610240632 A CN201610240632 A CN 201610240632A CN 105727432 A CN105727432 A CN 105727432A
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- Prior art keywords
- particle
- recyclable
- radioactive
- radioactive particle
- conformal
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- 239000002245 particle Substances 0.000 title claims abstract description 107
- 230000002285 radioactive effect Effects 0.000 title claims abstract description 74
- 239000000463 material Substances 0.000 claims abstract description 16
- 230000005855 radiation Effects 0.000 claims description 15
- XBBVURRQGJPTHH-UHFFFAOYSA-N 2-hydroxyacetic acid;2-hydroxypropanoic acid Chemical compound OCC(O)=O.CC(O)C(O)=O XBBVURRQGJPTHH-UHFFFAOYSA-N 0.000 claims description 4
- 238000007920 subcutaneous administration Methods 0.000 claims description 4
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 3
- 206010028980 Neoplasm Diseases 0.000 abstract description 41
- 208000005189 Embolism Diseases 0.000 abstract description 4
- 230000006378 damage Effects 0.000 abstract description 4
- 238000000638 solvent extraction Methods 0.000 abstract 2
- 208000001435 Thromboembolism Diseases 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 6
- 239000001569 carbon dioxide Substances 0.000 description 5
- 229910002092 carbon dioxide Inorganic materials 0.000 description 5
- 239000004744 fabric Substances 0.000 description 5
- 230000002980 postoperative effect Effects 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 208000019155 Radiation injury Diseases 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 238000001959 radiotherapy Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Natural products OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 230000003301 hydrolyzing effect Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 230000002132 lysosomal effect Effects 0.000 description 2
- 210000002540 macrophage Anatomy 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 2
- 239000004531 microgranule Substances 0.000 description 2
- 230000000242 pagocytic effect Effects 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000010146 3D printing Methods 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000005844 autocatalytic reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 210000004292 cytoskeleton Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 229930182851 human metabolite Natural products 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1014—Intracavitary radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1009—Apparatus for loading seeds into magazines or needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/101—Magazines or cartridges for seeds
Abstract
The invention discloses a recyclable conformal radioactive particle cabin which comprises a fixing plate, a guide column and a plurality of moveable partitioning plates, wherein the guide column is longitudinally arranged at the lower end of the fixing plate; the guide column is made of a flexible material; the moveable partitioning plates are overlapped with one another up and down and are arranged on the guide column in a sliding sleeve manner. According to a preoperative plan, under the image guide, a puncture needle is penetrated into a tumor; the tip position is a tail end particle position of the preoperative plan; a needle core is pulled out, the recyclable conformal radioactive particle cabin is placed into a puncture needle tube and pushed to a particle distribution source position specified in the preoperative plan. As the guide column is made of the flexible material, the guide column can have conformal deformation along with change of the tumor, and the recyclable conformal radioactive particle cabin can be taken out after the tumor is eliminated, radioactive particles can be taken out, the consequence that the distribution sources of the radioactive particles in the tumor can be accumulated with one another to generate high-dosage areas along with reduction of the tumor size and radioactive damage of normal tissue around is caused be effectively prevented, and meanwhile particle migration and complication such as lumen obstruction and thromboembolism can be prevented.
Description
Technical field
The present invention relates to and relate to medical instruments field, be specifically related to a kind of recyclable conformal radiation particle cabin.
Background technology
In recent years, along with the development of less invasive techniques, the advantages such as radioactive particle (such as 125I) implantation is little with wound, simple to operate, effective and receive publicity gradually.Treating malignant tumor is stepped into a brand-new field, there is great competitive advantage compared with existing Therapeutic Method.But, may have the disadvantage that after radioactive prospecting instrument tumor body that 1. radioactive particles cloth source in tumor body can mutually be assembled along with reducing of gross tumor volume and produce high dose area, cause the radiation injury of normal surrounding tissue.2. being not easily taken out in seeds implanted tumor body, patient generally can carry throughout one's life.3. in radioactive prospecting instrument art and postoperative it may happen that migrate, may come off after tumor regression, even result in tube chamber block, the complication such as blood vessel embolism, or because of the existence of radiant, easily cause the damage of other normal structures or organ.Such as hemorrhage, perforation etc..4. radioactive particle is not because taking out after implanting tumor body, so can not change according to tumor body target volume, adjusts the dose distribution of covered tumor body.
Summary of the invention
The present invention is in order to overcome the deficiency of above technology, it is provided that a kind of recyclable conformal radiation particle cabin with good conformal performance.
The present invention overcomes its technical problem be the technical scheme is that
A kind of recyclable conformal radiation particle cabin, this radioactive particle storehouse includes: fixing plate, it is longitudinally disposed at the guide pillar being made up of flexible material of fixing plate lower end and some active clapboards that mutually stacked on top of one another and slip cap are loaded on guide pillar, radioactive particle storage chamber is formed between active clapboard and fixing plate topmost and between the adjacent portable plate of each two, described radioactive particle storage intracavity is provided with fixing device, radioactive particle is fixed on radioactive particle storage intracavity by fixing device, and the upper surface of the bottom of the radioactive particle active clapboard adjacent with its lower end contacts.
In order to take out smoothly, the upper end of above-mentioned fixing plate is provided with tip I.
For the ease of take out, also include the body surface draught line being fixed on fixing plate upper end, described body surface draught line adopt anticorrosive, there is flexibility and do not have with human body the material of rejection to make.
In order to make radioactive particle be easy to location, the upper end center position of above-mentioned active clapboard is provided with groove, and the internal diameter of described groove and the external diameter of radioactive particle match.
Above-mentioned fixing device is the Elastic clamping plate being symmetricly set in radioactive particle both sides, and described Elastic clamping plate is vertically arranged with the arc groove matched with radioactive particle external diameter, and in its natural state, the distance between two Elastic clamping plates is less than the external diameter of radioactive particle.
For the Direct perforantes suitable in superficial tumor, also include being wrapped in radioactive particle side out of my cabin and by flexibility and possess the sheath pipe that biodegradable material is made.
For the ease of burying under the skin, the head end of above-mentioned table draught line is provided with dismountable and is fixed on body surface or is imbedded at the retainer ring of subcutaneous annular.
Above-mentioned body surface draught line adopts titanium alloy wire.
For the ease of puncturing, the tail end of above-mentioned sheath pipe is provided with tip II.
Above-mentioned sheath pipe adopts poly (lactic acid-glycolic acid) material use heat to melt or 3D prints and makes.
The invention has the beneficial effects as follows: utilize TPS radiotherapy planning system to make preoperative plan, system simulates the position of radioactive particle implanting tumor body and interparticle distance from.According to preoperative plan, radioactive particle is inserted in particle cabin, regulate active clapboard and adjust interparticle distance.Radioactive particle cabin ensure that interparticle actual pitch is corresponding with the interparticle distance of simulation.Under image-guided, puncture needle is penetrated in tumor body.Tip position is preoperative plan end particle position.Extract nook closing member, this radioactive particle cabin is inserted in puncture needle tubing, and be pushed into the particle cloth source position of preoperative plan regulation.For superficial tumor, select the puncture sheath pipe box of appropriate length on particle cabin, the particle cabin being cased with puncturing sheath pipe is implanted directly into tumor body, utilizes retainer ring to be fixed on body surface.Owing to guide pillar is made up of flexible material, therefore it can the conformal change along with the change of tumor, when after tumor regression, this radioactive particle cabin entirety can be taken out by retainer ring and draught line, it is achieved thereby that the taking-up of radioactive particle, effectively prevent the radioactive particle cloth source in tumor body from can mutually assemble along with reducing of gross tumor volume and producing high dose area, cause the radiation injury of normal surrounding tissue.Prevent in radioactive prospecting instrument art and postoperative it may happen that migrate, may come off after tumor regression simultaneously, even result in tube chamber block, the complication such as blood vessel embolism, or because of the existence of radiant, easily cause the damage of other normal structures or organ.Such as hemorrhage, perforation etc..If the volume that particle dose and tumor target reduce is incompatible, particle cabin can be taken out, readjust interparticle distance from and replacing particle, effectively control particle dose.
Accompanying drawing explanation
Fig. 1 is the structural representation of the present invention;
Fig. 2 is the Elastic clamping plate cross-sectional structure schematic diagram of the present invention;
Fig. 3 is the portable plate cross-sectional view of the present invention;
Fig. 4 is the sheath tubular construction schematic diagram of the present invention;
In figure, 1. retainer ring 2. body surface draught line 3. fixes plate 4. tip I 5. guide pillar 6. active clapboard 7. Elastic clamping plate 8. radioactive particle 9. arc groove 10. groove 11. sheath pipe 12. tip II.
Detailed description of the invention
Below in conjunction with accompanying drawing 1, accompanying drawing 2, accompanying drawing 3, the present invention will be further described for accompanying drawing 4.
A kind of recyclable conformal radiation particle cabin, this radioactive particle storehouse includes: fixing plate 3, it is longitudinally disposed at the guide pillar 5 being made up of flexible material of fixing plate 3 lower end and some active clapboards 6 that mutually stacked on top of one another and slip cap are loaded on guide pillar 5, radioactive particle storage chamber is formed between active clapboard 6 and fixing plate 3 topmost and between the adjacent portable plate 6 of each two, radioactive particle storage intracavity is provided with fixing device, radioactive particle 8 is fixed on radioactive particle storage intracavity by fixing device, and the upper surface of the bottom of radioactive particle 8 active clapboard 6 adjacent with its lower end contacts.Carry out operation consent, give prescribed dose and the initial activity of particle.Preoperative image (such as CT, ultrasonic etc.) is imported TPS radiotherapy planning system, drawing target outline, system simulates the position of the radioactive particle implanting tumor body and interparticle distance from.DVH figure before logistic.After preoperative plan is carried out, radioactive particle 8 is fixed in each radioactive particle storage chamber by fixing device, regulates the spacing of each active clapboard 6 afterwards, thus it is corresponding with the interparticle distance of simulation to reach interparticle actual pitch.According to preoperative plan, under image-guided, puncture needle is penetrated in tumor body.Tip position is preoperative plan end particle position.Extract nook closing member, this radioactive particle cabin is inserted in puncture needle tubing, and be pushed into the particle cloth source position of preoperative plan regulation.Postoperative image is imported the postoperative DVH figure of TPS radiotherapy planning system-computed.Owing to guide pillar 5 is made up of flexible material, therefore it can follow the change of tumor and conformal change, therefore it can the conformal change along with the change of tumor, when after tumor regression, this radioactive particle cabin entirety can be taken out by retainer ring 1 and draught line 2, it is achieved thereby that the taking-up of radioactive particle 8, effectively prevent the radioactive particle 8 cloth source in tumor body from can mutually assemble along with reducing of gross tumor volume and producing high dose area, cause the radiation injury of normal surrounding tissue.Prevent in radioactive particle 8 implantation and postoperative it may happen that migrate, may come off after tumor regression simultaneously, even result in tube chamber block, the complication such as blood vessel embolism, or because of the existence of radiant, easily cause the damage of other normal structures or organ.Such as hemorrhage, perforation etc..If the volume that particle dose and tumor target reduce is incompatible, particle cabin can be taken out, readjust interparticle distance from and replacing particle, effectively control particle dose.
The upper end of fixing plate 3 is provided with tip I 4, when needs by this radioactive particle cabin from internal taking-up time, tip I 4 can make it pass through tissue, improves the convenience using operation.Further, it is also possible to include the body surface draught line 2 being fixed on fixing plate 3 upper end, body surface draught line 2 adopt anticorrosive, have flexibility and do not have with human body rejection or repel lighter material make.Body surface draught line 2 will not be corroded, and when being embedded in subcutaneous, particle cabin, without producing serious rejection, is extracted by itself and human body such that it is able to pass through body surface draught line 2.Further, body surface draught line 2 can adopt titanium alloy wire.The head end of table draught line 2 is provided with dismountable and is fixed on body surface or is imbedded at the retainer ring 1 of subcutaneous annular.Retainer ring 1 being buried under the skin after this radioactive particle cabin is implanted to inside tumor and sew up, taking out retainer ring 1 after tumor regression, doctor can pass through retainer ring 1 and conveniently pull body surface draught line 2, further increases the convenience of operation.
The upper end center position of active clapboard 6 is provided with the external diameter of groove 10, the internal diameter of groove 10 and radioactive particle 8 and matches.The bottom of radioactive particle 8 can make fixing device be quickly fixedly clamped by radioactive particle 8 according to tram after being initially inserted in groove 10 to realize location, it is achieved that the quickly purpose of location and installation radioactive particle.Fixing device can be following structure: be symmetricly set in the Elastic clamping plate 7 of radioactive particle 8 both sides, Elastic clamping plate 7 is vertically arranged with the arc groove 9 matched with radioactive particle 8 external diameter, in its natural state, the distance between two Elastic clamping plates 7 is less than the external diameter of radioactive particle 8.Radioactive particle 8 two ends are placed in arc groove 9, and are strutted by Elastic clamping plate 7, and radioactive particle 8 is fixedly clamped by the Elastic clamping plate 7 of both sides.
Further, it is also possible to include being wrapped in radioactive particle side out of my cabin and by flexibility and possess the sheath pipe 11 that biodegradable material is made.For superficial tumor, it is convenient to omit being pushed in radioactive particle cabin after lancet puncture and put in place, it directly utilizes sheath pipe 11 and is punctured to tumor locus.Along with sheath pipe 11 decomposes gradually, the radioactive particle cabin of soft inner can be gradually curved along with tumor mass reduction, reaches conformal effect.If be implanted into particle chemical therapy in radioactive particle cabin, sheath pipe 11 can be combined formation chemotherapy slow releasing agent with the chemical microgranule in particle cabin, reduces chemical microgranule degradation speed in tumor body.Sheath pipe 11 can adopt poly (lactic acid-glycolic acid) material use heat to melt or 3D prints and makes.3D printing and making precision is high, and poly (lactic acid-glycolic acid) (PLGA) is the copolymer of polylactic acid (PLA) and polyglycolic acid (PGA), is used for preparing biodegradable pharmaceutical carrier and cytoskeleton, has good biocompatibility and safety.PLGA internal metabolism produces lactic acid and glycolic mainly by ester linkage hydrolyzing, and end product excretes with the form of carbon dioxide (CO2) and water, metabolite safety.The internal metabolism degraded mainly ester linkage hydrolyzing of PLGA, accelerates hydrolysis by autocatalysis and macrophage phagocytic and lysosomal enzymes effect thereof;Major part by macrophage phagocytic, can be hydrolyzed by lysosomal enzyme in blood;Hydrolyzate is lactic acid and glycolic, and lactic acid enters tricarboxylic acid cycle and participates in energy metabolism, and end product is excreted by lungs and kidney with the form of CO2 and water;And glycolic can metabolic conversion be normal human's metabolite such as CO2, glycine or acetone acid, excreting with the form of CO2 and water, through the prototype polymer very trace that urine is discharged, internal do not have cumulative appearance.Therefore when this radioactive particle cabin being extracted from internal either directly through body surface draught line 2 after sheath pipe 11 degraded after tumor regression.Further, the tail end of sheath pipe 11 is provided with tip II 12, and tip II 12 can be inclined-plane or pyramidal structure.Sheath pipe 11 can pass through tip II 12 and conveniently be inserted in superficial tumor.
Claims (10)
1. a recyclable conformal radiation particle cabin, it is characterized in that, this radioactive particle storehouse includes: fixing plate (3), it is longitudinally disposed at the guide pillar (5) being made up of flexible material of fixing plate (3) lower end and some active clapboards (6) that mutually stacked on top of one another and slip cap are loaded on guide pillar (5), it is positioned between active clapboard (6) and fixing plate (3) topmost and forms radioactive particle between portable plate (6) that each two is adjacent and store chamber, described radioactive particle storage intracavity is provided with fixing device, radioactive particle (8) is fixed on radioactive particle storage intracavity by fixing device, and the upper surface of the bottom of radioactive particle (8) active clapboard (6) adjacent with its lower end contacts.
2. recyclable conformal radiation particle cabin according to claim 1, it is characterised in that: the upper end of described fixing plate (3) is provided with tip I (4).
3. recyclable conformal radiation particle cabin according to claim 1, it is characterized in that: also include being fixed on the body surface draught line (2) of fixing plate (3) upper end, described body surface draught line (2) adopt anticorrosive, there is flexibility and do not have with human body the material of rejection to make.
4. recyclable conformal radiation particle cabin according to claim 1, it is characterised in that: the upper end center position of described active clapboard (6) is provided with the external diameter of groove (10), the internal diameter of described groove (10) and radioactive particle (8) and matches.
5. recyclable conformal radiation particle cabin according to claim 1, it is characterized in that: described fixing device is the Elastic clamping plate (7) being symmetricly set in radioactive particle (8) both sides, described Elastic clamping plate (7) is vertically arranged with the arc groove (9) matched with radioactive particle (8) external diameter, in its natural state, the distance between two Elastic clamping plates (7) is less than the external diameter of radioactive particle (8).
6. recyclable conformal radiation particle cabin as claimed in any of claims 1 to 5, it is characterised in that: also include being wrapped in radioactive particle side out of my cabin and by flexibility and possess the sheath pipe (11) that biodegradable material is made.
7. recyclable conformal radiation particle cabin according to claim 2, it is characterised in that: the head end of described body surface draught line (2) is provided with dismountable and is fixed on body surface or is imbedded at the retainer ring (1) of subcutaneous annular.
8. recyclable conformal radiation particle cabin according to claim 3, it is characterised in that: described body surface draught line (2) adopts titanium alloy wire.
9. recyclable conformal radiation particle cabin according to claim 6, it is characterised in that: the tail end of described sheath pipe (11) is provided with tip II (12).
10. recyclable conformal radiation particle cabin according to claim 6, it is characterised in that: described sheath pipe (11) adopts poly (lactic acid-glycolic acid) material use heat to melt or 3D prints and makes.
Priority Applications (1)
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CN201610240632.4A CN105727432A (en) | 2016-04-19 | 2016-04-19 | Recyclable conformal radioactive particle cabin |
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CN201610240632.4A CN105727432A (en) | 2016-04-19 | 2016-04-19 | Recyclable conformal radioactive particle cabin |
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CN105727432A true CN105727432A (en) | 2016-07-06 |
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CN201610240632.4A Pending CN105727432A (en) | 2016-04-19 | 2016-04-19 | Recyclable conformal radioactive particle cabin |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111803017A (en) * | 2020-09-09 | 2020-10-23 | 季华实验室 | Endoscopic device for diagnosis of digestive tract and pipeline device for treatment of digestive tract |
CN112451850A (en) * | 2020-12-11 | 2021-03-09 | 王姗姗 | Iodine-125 particle is with implanting device |
CN112755412A (en) * | 2021-02-26 | 2021-05-07 | 张宏涛 | External measuring device and method for radioactive particle implantation dose |
CN113144410A (en) * | 2021-06-07 | 2021-07-23 | 哈尔滨理工大学 | Radioactive particle taking-out device |
CN113198098A (en) * | 2021-06-11 | 2021-08-03 | 哈尔滨理工大学 | Radioactive particle resetting device |
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CN111803017A (en) * | 2020-09-09 | 2020-10-23 | 季华实验室 | Endoscopic device for diagnosis of digestive tract and pipeline device for treatment of digestive tract |
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CN113198098A (en) * | 2021-06-11 | 2021-08-03 | 哈尔滨理工大学 | Radioactive particle resetting device |
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Application publication date: 20160706 |