CN112402575A - External ointment for treating psoriasis and preparation method thereof - Google Patents
External ointment for treating psoriasis and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external ointment for treating psoriasis and a preparation method thereof. The external ointment for treating psoriasis comprises the following raw materials in parts by weight: 10-20 parts of coptis chinensis, 10-20 parts of phellodendron, 10-20 parts of turmeric, 10-20 parts of angelica sinensis, 10-20 parts of radix rehmanniae recen and 10-20 parts of dendrobium nobile. The external ointment for treating psoriasis has the effects of clearing damp, relieving itching, repairing and regenerating, cleaning and nourishing, protecting the skin, smoothing and moistening the skin, relieving the skin discomfort and having the health-care effects of repairing and promoting the skin health.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external ointment for treating psoriasis and a preparation method thereof.
Background
Psoriasis is commonly referred to as psoriasis, a common chronic, easily relapsing inflammatory skin disease with characteristic skin lesions. The early stage is inflammatory red papule, about millet to mung bean in size, and then gradually expands or fuses into brownish red plaque with clear boundary, inflammatory red halo around the plaque, obvious substrate infiltration, and multiple layers of dry grey-white or silvery-white scales on the surface. The surface scale is scraped off slightly, and a layer of pale red and bright semitransparent film is gradually exposed, which is called the film phenomenon. When the film is scraped off, a small bleeding spot appears, which is called a spot bleeding phenomenon. White scales, shiny films and punctate bleeding are important features for diagnosing psoriasis, called triple features. Psoriasis vulgaris lesions can be roughly divided into three periods from occurrence to eventual regression: an advance period, a rest period, and a retreat period.
The traditional Chinese medicine considers that the main causes of the psoriasis are wind-heat and dampness attacking the skin externally, the psoriasis is suffered from the skin and blood system of a human body and is suffered from skin and channel blockage, or the psoriasis is caused by emotional depression, fire transformation due to depression, improper diet, damp-heat generation internally, fire depression, deficiency of qi and blood, malnutrition of the skin of the channel, dryness and desquamation after a long time. At present, more traditional Chinese medicines are used for treating the disease, but the truly effective scheme with breakthrough significance is less.
Disclosure of Invention
The invention aims to provide an external ointment for treating psoriasis.
The invention also aims to provide a preparation method of the external ointment for treating psoriasis.
According to the specific embodiment of the invention, the external ointment for treating psoriasis comprises the following raw materials in parts by weight: 10-20 parts of coptis chinensis, 10-20 parts of phellodendron, 10-20 parts of turmeric, 10-20 parts of angelica sinensis, 10-20 parts of radix rehmanniae recen and 10-20 parts of dendrobium nobile.
According to the external ointment for treating psoriasis, the external ointment for treating psoriasis further comprises 50-100 parts of sesame oil, 20-40 parts of white vaseline and 10-20 parts of beeswax.
According to the specific embodiment of the invention, the external ointment for treating psoriasis comprises the following raw materials in parts by weight: 10 parts of coptis chinensis, 10 parts of golden cypress, 10 parts of turmeric, 10 parts of angelica, 10 parts of radix rehmanniae recen, 10 parts of dendrobium, 50 parts of sesame oil, 20 parts of white vaseline and 10 parts of beeswax.
According to the specific embodiment of the invention, the external ointment for treating psoriasis comprises the following raw materials in parts by weight: 20 parts of coptis chinensis, 20 parts of golden cypress, 20 parts of turmeric, 20 parts of angelica, 20 parts of radix rehmanniae recen, 20 parts of dendrobium, 100 parts of sesame oil, 40 parts of white vaseline and 20 parts of beeswax.
According to the specific embodiment of the invention, the external ointment for treating psoriasis comprises the following raw materials in parts by weight: 15 parts of coptis chinensis, 15 parts of golden cypress, 15 parts of turmeric, 15 parts of Chinese angelica, 15 parts of radix rehmanniae recen, 15 parts of dendrobium, 75 parts of sesame oil, 30 parts of white vaseline and 15 parts of beeswax.
According to the embodiment of the invention, the preparation method of the external ointment for treating psoriasis comprises the following steps: taking the following raw materials in parts by weight: 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of turmeric, 10-20 parts of angelica sinensis, 10-20 parts of radix rehmanniae recen and 10-20 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes.
According to the external ointment for treating psoriasis, 50-100 parts of sesame oil, 20-40 parts of white vaseline and 10-20 parts of beeswax are heated to 95-105 ℃, and the raw material fine powder is added and uniformly stirred.
According to the embodiment of the invention, the preparation method of the external ointment for treating psoriasis comprises the following steps: taking the following raw materials in parts by weight: 10 parts of coptis chinensis, 10 parts of golden cypress, 10 parts of turmeric, 10 parts of angelica, 10 parts of radix rehmanniae recen and 10 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 50 parts, white vaseline 20 parts and Cera flava 10 parts to 95 deg.C, adding the fine powder, and stirring.
According to the embodiment of the invention, the preparation method of the external ointment for treating psoriasis comprises the following steps: taking the following raw materials in parts by weight: 20 parts of coptis chinensis, 20 parts of golden cypress, 20 parts of turmeric, 20 parts of angelica, 20 parts of radix rehmanniae recen and 20 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 100 parts, white vaseline 40 parts and Cera flava 20 parts to 105 deg.C, adding the fine powder, and stirring.
According to the embodiment of the invention, the preparation method of the external ointment for treating psoriasis comprises the following steps: taking the following raw materials in parts by weight: 15 parts of coptis chinensis, 15 parts of golden cypress, 15 parts of turmeric, 15 parts of angelica, 15 parts of radix rehmanniae recen and 15 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 75 parts, white vaseline 30 parts and Cera flava 15 parts to 100 deg.C, adding the fine powder, and stirring.
Coptidis rhizoma is perennial herb of Coptis of Ranunculaceae. Alias: rhizoma Coptidis, and rhizoma Coptidis. Huang Lian is bitter in taste and cold in nature. It enters heart, spleen, stomach, liver, gallbladder and large intestine meridians. Has the effects of clearing heat, eliminating dampness, purging fire and removing toxicity. Mainly treats damp-heat fullness, vomiting and acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactivity of heart-fire, vexation and insomnia, palpitation and restlessness, blood heat and hematemesis and epistaxis, conjunctival congestion, toothache, diabetes, carbuncle and swelling and sore; it is used externally to treat eczema, eczema and purulent ear canal.
Cortex Phellodendri is dried bark of Phellodendron chinense Schneid of Rutaceae. Bitter taste and cold nature. It enters kidney and bladder meridians. Has the effects of clearing heat, eliminating dampness, purging fire, removing steam, removing toxic substance and treating sore. Can be used for treating dysentery due to damp-heat pathogen, jaundice, dark urine, leukorrhagia, pudendal pruritus, pyretic stranguria, pain, tinea pedis, atrophic debility cramped, hectic fever, night sweat, nocturnal emission, pyocutaneous disease, toxic swelling, eczema, and eczema. Salted cortex phellodendri is used for nourishing yin and reducing internal heat. Can be used for treating hyperactivity of fire due to yin deficiency, night sweat and steaming bone.
Turmeric (Latin's name: Curcuma longa L.) also known as Curcuma longa: turmeric root-tuber, Baodingxiang, Chinese ephedra, ginger, etc. Pungent and bitter with warm property. Enter spleen and liver meridians. Break blood, move qi, unblock meridians, and alleviate pain. It is indicated for abdominal fullness and distention, brachialgia, abdominal mass, amenorrhea due to blood stasis, postpartum abdominal pain due to stasis, traumatic injury, carbuncle and swelling. For chest and abdominal pain, dysmenorrhea and limb pain due to qi stagnation and blood stasis, it is often combined with rhizoma corydalis and cyperi.
Angelica sinensis (Oliv.) Diels is dried root of Angelica sinensis (Oliv.) Diels, Umbelliferae. Sweet and pungent in flavor and warm in nature. It enters liver, heart and spleen meridians. Tonify blood, activate blood, regulate menstruation, alleviate pain, moisten intestines to relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
Dried Rehmannia root (Latin scientific name: Rehmannia glutinosa (Gaetn.) Libosch. ex Fisch. et Mey.) is a perennial herb of the genus Rehmannia of the family Scrophulariaceae. Sweet in nature and taste and cold in nature. It enters heart, liver and kidney meridians. Rehmannia is cool in nature and sweet and bitter in taste, and has the effects of nourishing yin, tonifying kidney, nourishing blood, enriching blood and cooling blood. It is beneficial to be taken by patients with yin deficiency, blood deficiency and kidney deficiency. In addition, rehmanniae radix has effects of tonifying heart, promoting diuresis, relieving fever, relieving inflammation, promoting blood coagulation and reducing blood sugar. Clear heat and cool blood, nourish yin, promote the production of body fluid. Can be used for treating fever with deep-red tongue, polydipsia, yin deficiency, internal heat, bone steaming, internal heat, diabetes, hematemesis, epistaxis, macula, and eruption.
Dendrobium nobile is a cultivated product of Dendrobium nobile Lindl, Dendrobium chrysotoxum Lindl or Dendrobium fimbriatum hook of Orchidaceae and a fresh or dry stem of similar species of plants of the same genus. Sweet in flavor and slightly cold in nature. It enters stomach and kidney meridians. To nourish stomach, promote the production of body fluid, nourish yin and clear heat. Can be used for treating fever, body fluid consumption, dry mouth, polydipsia, stomach yin deficiency, anorexia, retching, persistent asthenic fever after illness, hyperactivity of fire due to yin deficiency, bone steaming, fatigue, dim eyesight, and flaccidity of tendons and bones.
The sesame oil is sesame seed oil. The squeezed seeds are sesame oil. Sesame oil, which is edible with black sesame, and white sesame oil, which is fatty oil extracted from sesame seeds of the family Pedaliaceae, and is also called flax, oil sesame, Jusheng, sesame and sesame oil.
The white petrolatum is white vaseline. Vaseline is petrolatum obtained by fractionating petroleum, and petrolatum is a semi-liquid mixture of alkane or saturated hydrocarbon. The state of the product is between solid and liquid at normal temperature, and the product has three colors of brown, yellow and white due to different purposes.
Yellow wax, also called "beeswax", is the wax secreted by worker bees and is mainly used for building nests. Detoxicating, promoting granulation, stopping dysentery, stopping bleeding, and relieving pain. Mainly treats carbuncle, cellulitis and back, and ulcer is astringing, dysentery with purulent blood, acute cardialgia; persistent diarrhea, spermatorrhea, leukorrhagia, fetal movement and bleeding.
The invention has the beneficial effects that:
the external ointment disclosed by the invention is prepared from coptis chinensis, golden cypress, turmeric, Chinese angelica, radix rehmanniae recen and dendrobium, has the effects of clearing damp, relieving itching, repairing, regenerating, cleaning and nourishing skin, protecting the skin, smoothing and moistening the skin, relieving discomfort of the skin, repairing and promoting the health of the skin, can be used for auxiliary treatment of early psoriasis, enhances the effects of detoxifying and healing sore after the golden cypress and the dendrobium are matched, and particularly has a good effect on red spot rash of early psoriasis.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
The external ointment for treating psoriasis comprises the following raw materials: 10g of coptis chinensis, 10g of golden cypress, 10g of turmeric, 10g of angelica sinensis, 10g of radix rehmanniae recen, 10g of dendrobium, 50g of sesame oil, 20g of white vaseline and 10g of beeswax.
The preparation method of the external ointment for treating psoriasis comprises the following steps:
pulverizing Coptidis rhizoma, cortex Phellodendri, Curcuma rhizome, radix Angelicae sinensis, radix rehmanniae, and herba Dendrobii into Chinese medicinal fine powder of 100 meshes or less;
heating oleum Sesami, white vaseline and Cera flava to 100 deg.C, adding the fine powder, stirring, and condensing.
Example 2
The external ointment for treating psoriasis comprises the following raw materials: 20g of coptis chinensis, 20g of phellodendron, 20g of turmeric, 20g of angelica, 20g of radix rehmanniae recen, 20g of dendrobium, 100g of sesame oil, 40g of white vaseline and 20g of beeswax.
The preparation method of the external ointment for treating psoriasis comprises the following steps:
pulverizing Coptidis rhizoma, cortex Phellodendri, Curcuma rhizome, radix Angelicae sinensis, radix rehmanniae, and herba Dendrobii into Chinese medicinal fine powder of 100 meshes or less;
heating oleum Sesami, white vaseline and Cera flava to 100 deg.C, adding the fine powder, stirring, and condensing.
Example 3
The external ointment for treating psoriasis comprises the following raw materials:
15g of coptis chinensis, 15g of golden cypress, 15g of turmeric, 15g of Chinese angelica, 15g of radix rehmanniae recen, 15g of dendrobium, 75g of sesame oil, 30g of white vaseline and 15g of beeswax.
The preparation method of the external ointment for treating psoriasis comprises the following steps:
pulverizing Coptidis rhizoma, cortex Phellodendri, Curcuma rhizome, radix Angelicae sinensis, radix rehmanniae, and herba Dendrobii into Chinese medicinal fine powder of 100 meshes or less;
heating oleum Sesami, white vaseline and Cera flava to 100 deg.C, adding the fine powder, stirring, and condensing.
The application and dosage of the external ointment for treating psoriasis of the invention are as follows:
it is applied topically to affected parts 1-2 times daily, and the skin with thick skin is sealed with preservative film.
Example 4
Experimental groups: example 1.
Control group 1: 10g of coptis chinensis, 10g of turmeric, 10g of angelica sinensis, 10g of radix rehmanniae recen, 10g of dendrobium nobile, 50g of sesame oil, 20g of white vaseline and 10g of beeswax. The preparation method is the same as example 1.
Control group 2: 10g of coptis chinensis, 10g of phellodendron, 10g of turmeric, 10g of angelica, 10g of radix rehmanniae recen, 50g of sesame oil, 20g of white vaseline and 10g of beeswax. The preparation method is the same as example 1.
60 patients, 36 men and 24 women, who are clinically diagnosed with psoriasis, are selected, and all the patients are early-stage psoriasis patients with early-stage symptoms of pinhead or mung bean red spot rash, small skin lesion area and pruritus.
The ointment is applied to affected parts in the morning and evening respectively by using topical ointment of experimental group, control group 1 and control group 2, and 3 groups of 60 patients at random. After 1 month of continuous use, the affected part of the patient was observed, and the experimental results are shown in Table 1.
Wherein, the healing is that the spot rash of the skin of the affected part coated with the ointment disappears, and the skin is smooth;
the effective effect is that the area of skin rash of the affected part coated with the ointment is reduced;
the ineffective effect is that the skin rash area of the affected part coated with the ointment is not improved.
TABLE 1 therapeutic Effect of the experimental group and the control group
| Group of | Number of examples | Cure of disease | Show effect | Invalidation | Overall efficiency rate |
| Experimental group | 20 | 13 | 3 | 4 | 80％ |
| Control group 1 | 20 | 2 | 1 | 17 | 15％ |
| Control group 2 | 20 | 3 | 2 | 15 | 25％ |
As shown in Table 1, the combination of phellodendron and dendrobium in the experimental group has good curative effect on rash of psoriasis in early stage, and can repair, regenerate, clean and nourish the skin to make the skin of the affected part smooth and clean; and after the compositions of the control group 1 and the control group 2 lack the phellodendron or the dendrobium, the effect of the external ointment on rash is obviously reduced. Therefore, the phellodendron and dendrobium in the external ointment composition have a synergistic effect, and have a good curative effect on rash of early psoriasis.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. The external ointment for treating psoriasis is characterized by comprising the following raw materials in parts by weight: 10-20 parts of coptis chinensis, 10-20 parts of phellodendron, 10-20 parts of turmeric, 10-20 parts of angelica sinensis, 10-20 parts of radix rehmanniae recen and 10-20 parts of dendrobium nobile.
2. The external ointment for treating psoriasis as claimed in claim 1, further comprising 50 to 100 parts of sesame oil, 20 to 40 parts of white vaseline and 10 to 20 parts of beeswax.
3. The external ointment for treating psoriasis according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 10 parts of coptis chinensis, 10 parts of golden cypress, 10 parts of turmeric, 10 parts of angelica, 10 parts of radix rehmanniae recen, 10 parts of dendrobium, 50 parts of sesame oil, 20 parts of white vaseline and 10 parts of beeswax.
4. The external ointment for treating psoriasis according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 20 parts of coptis chinensis, 20 parts of golden cypress, 20 parts of turmeric, 20 parts of angelica, 20 parts of radix rehmanniae recen, 20 parts of dendrobium, 100 parts of sesame oil, 40 parts of white vaseline and 20 parts of beeswax.
5. The external ointment for treating psoriasis according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 15 parts of coptis chinensis, 15 parts of golden cypress, 15 parts of turmeric, 15 parts of Chinese angelica, 15 parts of radix rehmanniae recen, 15 parts of dendrobium, 75 parts of sesame oil, 30 parts of white vaseline and 15 parts of beeswax.
6. The method for preparing an ointment for external use for treating psoriasis as set forth in claim 1, comprising the steps of: taking the following raw materials in parts by weight: 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of turmeric, 10-20 parts of angelica sinensis, 10-20 parts of radix rehmanniae recen and 10-20 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes.
7. The method for preparing an external ointment for treating psoriasis according to claim 6, wherein 50 to 100 parts of sesame oil, 20 to 40 parts of white vaseline and 10 to 20 parts of beeswax are heated to 95 to 105 ℃, and the fine powder of the raw materials are added and stirred uniformly.
8. The method for preparing an ointment for external use for treating psoriasis according to claim 6, wherein the method comprises the steps of: taking the following raw materials in parts by weight: 10 parts of coptis chinensis, 10 parts of golden cypress, 10 parts of turmeric, 10 parts of angelica, 10 parts of radix rehmanniae recen and 10 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 50 parts, white vaseline 20 parts and Cera flava 10 parts to 95 deg.C, adding the fine powder, and stirring.
9. The method for preparing an ointment for external use for treating psoriasis according to claim 6, wherein the method comprises the steps of: taking the following raw materials in parts by weight: 20 parts of coptis chinensis, 20 parts of golden cypress, 20 parts of turmeric, 20 parts of angelica, 20 parts of radix rehmanniae recen and 20 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 100 parts, white vaseline 40 parts and Cera flava 20 parts to 105 deg.C, adding the fine powder, and stirring.
10. The method for preparing an ointment for external use for treating psoriasis according to claim 6, wherein the method comprises the steps of: taking the following raw materials in parts by weight: 15 parts of coptis chinensis, 15 parts of golden cypress, 15 parts of turmeric, 15 parts of angelica, 15 parts of radix rehmanniae recen and 15 parts of dendrobium nobile; pulverizing the raw materials into fine powder of less than 100 meshes; heating oleum Sesami 75 parts, white vaseline 30 parts and Cera flava 15 parts to 100 deg.C, adding the fine powder, and stirring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011339195.4A CN112402575A (en) | 2020-11-25 | 2020-11-25 | External ointment for treating psoriasis and preparation method thereof |
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| CN202011339195.4A CN112402575A (en) | 2020-11-25 | 2020-11-25 | External ointment for treating psoriasis and preparation method thereof |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011339195.4A Pending CN112402575A (en) | 2020-11-25 | 2020-11-25 | External ointment for treating psoriasis and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN112402575A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1190009A (en) * | 1997-02-04 | 1998-08-12 | 林恒 | Skin moistening ointment |
| CN104189228A (en) * | 2014-08-02 | 2014-12-10 | 吴俊贤 | Medicine ointment for treating psoriasis, as well as preparation method and application thereof |
| CN108553620A (en) * | 2018-05-30 | 2018-09-21 | 武汉润禾生物医药有限公司 | A kind of bacteriostasis spray and preparation method thereof for treating skin psoriasis |
-
2020
- 2020-11-25 CN CN202011339195.4A patent/CN112402575A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1190009A (en) * | 1997-02-04 | 1998-08-12 | 林恒 | Skin moistening ointment |
| CN104189228A (en) * | 2014-08-02 | 2014-12-10 | 吴俊贤 | Medicine ointment for treating psoriasis, as well as preparation method and application thereof |
| CN108553620A (en) * | 2018-05-30 | 2018-09-21 | 武汉润禾生物医药有限公司 | A kind of bacteriostasis spray and preparation method thereof for treating skin psoriasis |
Non-Patent Citations (3)
| Title |
|---|
| 刘卫兵，等: "综合疗法治疗银屑病疗效观察", 《人民军医》 * |
| 闫小宁，等编著: "《皮肤病中医特色诊疗》", 1 October 2017, 世界图书出版公司 * |
| 马利斌: "中药内服外用治疗慢性单纯性苔藓61例", 《上海中医药杂志》 * |
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Application publication date: 20210226 |