CN112402570A - 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用 - Google Patents

一种调理抑郁症导致的肝郁血虚的药物组合物及其应用 Download PDF

Info

Publication number
CN112402570A
CN112402570A CN202011410371.9A CN202011410371A CN112402570A CN 112402570 A CN112402570 A CN 112402570A CN 202011410371 A CN202011410371 A CN 202011410371A CN 112402570 A CN112402570 A CN 112402570A
Authority
CN
China
Prior art keywords
parts
depression
traditional chinese
blood deficiency
deficiency caused
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011410371.9A
Other languages
English (en)
Inventor
黄凯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHIMEN PEOPLE S HOSPITAL
Original Assignee
SHIMEN PEOPLE S HOSPITAL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHIMEN PEOPLE S HOSPITAL filed Critical SHIMEN PEOPLE S HOSPITAL
Priority to CN202011410371.9A priority Critical patent/CN112402570A/zh
Publication of CN112402570A publication Critical patent/CN112402570A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967—Lilium, e.g. tiger lily or Easter lily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明涉及中药技术领域，尤其涉及一种调理抑郁症导致的肝郁血虚的中药组合物，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：百合15‑30份，白芍10‑20份，当归身5‑15份，生地5‑15份，柴胡3‑10份，茯神5‑10份，酸枣仁5‑20份，丹参10‑15份，炒麦芽5‑20份，珍珠母5‑15份，炙甘草1‑5份，在调理抑郁症导致的肝郁血虚方面具有良好的治疗效果。

Description

一种调理抑郁症导致的肝郁血虚的药物组合物及其应用
技术领域
本发明涉及中药技术领域，尤其涉及一种调理抑郁症导致的肝郁血虚的药物组合物及其应用。
背景技术
抑郁症又称抑郁障碍，以显著而持久的心境低落为主要临床特征，是心境障碍的主要类型。临床可见心境低落与其处境不相称，情绪的消沉可以从闷闷不乐到悲痛欲绝，自卑抑郁，甚至悲观厌世，可有自杀企图或行为；甚至发生木僵；部分病例有明显的焦虑和运动性激越；严重者可出现幻觉、妄想等精神病性症状。每次发作持续至少2周以上、长者甚或数年，多数病例有反复发作的倾向，每次发作大多数可以缓解，部分可有残留症状或转为慢性。
从临床上看，抑郁症常导致肝郁血虚，即血液亏虚，肝气郁滞，以头晕眼花，两胁作胀，情志抑郁，多梦健忘，面白，舌淡紫，脉弦细等为常见症的证候。中医领域认为可从此方面进行调理，以辅助治疗抑郁症。
发明内容
本发明的目的在于提供一种调理抑郁症导致的肝郁血虚的药物组合物及其应用。
为了解决上述技术问题，本发明一种调理抑郁症导致的肝郁血虚的中药组合物。制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：
百合15-30份，白芍10-20份，当归身5-15份，生地5-15份，柴胡3-10份，茯神5-10份，酸枣仁5-20份，丹参10-15份，炒麦芽5-20份，珍珠母5-15份，炙甘草1-5份。
优选地，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：百合30份，白芍20份，当归身15份，生地15份，柴胡10份，茯神10份，酸枣仁20份，丹参15份，炒麦芽20份，珍珠母15份，炙甘草5份。
其中，所述的药物组合物在制备下述任一种药物中的应用：
1)治疗抑郁症的药物；
2)治疗抑郁症导致的肝郁血虚的药物；
3)调理抑郁症导致的肝郁血虚的药物。
本发明有益效果：本发明处方组成独特，方中君药为百合养阴清心、宁心安神，当归身补血养肝、润肠通便，为补血之要药。臣药为白芍养血敛阴、柔肝缓急，生地滋阴清热、润燥生津，柴胡、炒麦芽疏肝解郁。佐以酸枣仁、茯神、丹参养心安神，珍珠母平肝潜阳、安魂魄。使药为炙甘草调和诸药，共达养血疏肝、宁心安神之功。本方用药力取轻柔，避免了过于辛伐伤肝，符合抑郁症病久虚损多延及血分的特点重用百合且从肺方面考虑论治为本方的特色。
具体实施方式
下面结合实施例对本发明作进一步详细描述。
实施例一
一种调理抑郁症导致的肝郁血虚的药物组合物，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：
百合15份，白芍10份，当归身5份，生地5份，柴胡3份，茯神5份，酸枣仁5份，丹参10份，炒麦芽5份，珍珠母5份，炙甘草1份。
使用时，水煎服，1日1剂，早晚各一次服用。
实施例二
一种调理抑郁症导致的肝郁血虚的药物组合物，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：
百合20份，白芍15份，当归身10份，生地5份，柴胡3份，茯神5份，酸枣仁5份，丹参10份，炒麦芽5份，珍珠母5份，炙甘草3份。
使用时，水煎服，1日1剂，早晚各一次服用。
实施例三
百合25份，白芍15份，当归身8份，生地8份，柴胡6份，茯神8份，酸枣仁10份，丹参10份，炒麦芽10份，珍珠母10份，炙甘草3份。
使用时，水煎服，1日1剂，早晚各一次服用。
实施例四
一种调理抑郁症导致的肝郁血虚的药物组合物，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：
百合25份，白芍18份，当归身15份，生地10份，柴胡3份，茯神10份，酸枣仁15份，丹参15份，炒麦芽10份，珍珠母15份，炙甘草5份。
使用时，水煎服，1日1剂，早晚各一次服用。
实施例五
一种调理抑郁症导致的肝郁血虚的药物组合物，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：
百合30份，白芍20份，当归身15份，生地15份，柴胡10份，茯神10份，酸枣仁20份，丹参15份，炒麦芽20份，珍珠母15份，炙甘草5份。
使用时，水煎服，1日1剂，早晚各一次服用。
本方君药为百合养阴清心、宁心安神，当归身补血养肝、润肠通便，为补血之要药。臣药为白芍养血敛阴、柔肝缓急，生地滋阴清热、润燥生津，柴胡、炒麦芽疏肝解郁。佐以酸枣仁、茯神、丹参养心安神，珍珠母平肝潜阳、安魂魄。使药为炙甘草调和诸药，共达养血疏肝、宁心安神之功。本方用药力取轻柔，避免了过于辛伐伤肝，符合抑郁症病久虚损多延及血分的特点重用百合且从肺方面考虑论治为本方的特色。
在其它实施例中，如烦热象明显者可加黄连、知母；若兼痰湿者去生地，加郁金、石菖蒲、陈皮等。
以上内容仅为本发明的较佳实施例，对于本领域的普通技术人员，依据本发明的思想，在具体实施方式及应用范围上均会有改变之处，本说明书内容不应理解为对本发明的限制。

Claims (3)

1.一种调理抑郁症导致的肝郁血虚的中药组合物，其特征在于，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：百合15-30份，白芍10-20份，当归身5-15份，生地5-15份，柴胡3-10份，茯神5-10份，酸枣仁5-20份，丹参10-15份，炒麦芽5-20份，珍珠母5-15份，炙甘草1-5份。
2.根据权利要求1所述的一种调理抑郁症导致的肝郁血虚的中药组合物，其特征在于，制成所述中药组合物的活性成分的原料由下述质量份的中药材组成：百合30份，白芍20份，当归身15份，生地15份，柴胡10份，茯神10份，酸枣仁20份，丹参15份，炒麦芽20份，珍珠母15份，炙甘草5份。
3.根据权利要求1或2所述的药物组合物在制备下述任一种药物中的应用 ：
1）治疗抑郁症的药物；
2）治疗抑郁症导致的肝郁血虚的药物；
3）调理抑郁症导致的肝郁血虚的药物。
CN202011410371.9A 2020-12-04 2020-12-04 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用 Pending CN112402570A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011410371.9A CN112402570A (zh) 2020-12-04 2020-12-04 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011410371.9A CN112402570A (zh) 2020-12-04 2020-12-04 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用

Publications (1)

Publication Number Publication Date
CN112402570A true CN112402570A (zh) 2021-02-26

Family

ID=74829198

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011410371.9A Pending CN112402570A (zh) 2020-12-04 2020-12-04 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用

Country Status (1)

Country Link
CN (1) CN112402570A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144086A (zh) * 2021-05-24 2021-07-23 盛少琴 一种治疗围绝经期睡眠障碍的中药组合物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860655A (zh) * 2015-12-10 2017-06-20 邵杰 疏肝养颜中药组合物
CN109893646A (zh) * 2019-03-19 2019-06-18 南京星银药业集团有限公司 一种治疗抑郁症的组合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106860655A (zh) * 2015-12-10 2017-06-20 邵杰 疏肝养颜中药组合物
CN109893646A (zh) * 2019-03-19 2019-06-18 南京星银药业集团有限公司 一种治疗抑郁症的组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
丁小玲: "逍遥散加减治疗产后抑郁症34例", 《浙江中西医结合杂志》 *
何本鸿等: "《当代中医专科专病治验精华.精神病证券》", 31 December 2013, 中医古籍出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144086A (zh) * 2021-05-24 2021-07-23 盛少琴 一种治疗围绝经期睡眠障碍的中药组合物及其制备方法

Similar Documents

Publication Publication Date Title
CN104258310A (zh) 一种治疗肝气郁结型郁证的中药
CN102631579B (zh) 一种治疗脑外伤后综合征的口服中药制剂
CN102813839A (zh) 治疗血管神经性头痛的复方药物
CN102078462A (zh) 一种定喘药剂
CN112402570A (zh) 一种调理抑郁症导致的肝郁血虚的药物组合物及其应用
CN102697868A (zh) 一种能调节免疫力治愈红斑狼疮,荨麻疹,银屑病的药物
CN1839953A (zh) 一种治疗原发性血小板减少性紫癜病的药
CN103405719A (zh) 一种治疗抑郁症的药物
CN102228582B (zh) 一种治疗慢性气管炎、支气管炎引起的咳喘的药物
CN103610896A (zh) 一种治疗外感咳嗽的中药药物
CN107582838A (zh) 治疗热盛迫血所致血小板减少性紫癜的制剂及制备方法
CN102614301B (zh) 一种治疗骨病的组合物及制法
CN101979035A (zh) 一种治疗妇科白带异常的药物
CN101239140A (zh) 治疗牛皮癣的中药药物
CN101062364B (zh) 治疗犬温热病的药物
CN104606475A (zh) 一种治疗急、慢性咽喉炎的中药组合物及其制备方法
CN103611062B (zh) 一种治疗尿崩症的中药组合物
CN103751355B (zh) 一种具有提升白细胞效果的药物组合物
CN107296906A (zh) 中药组合物及其在肺炎治疗中的应用
CN101983712A (zh) 冠心病的新型治疗药物
CN101953943A (zh) 一种治疗慢性再生障碍性贫血的中药
CN102366594A (zh) 一种用于调节月经的中药
CN105998629A (zh) 一种治疗气滞血证的中药组合物
CN106620121A (zh) 一种治疗肝郁气滞型乳腺增生的中药组合物
CN102727747B (zh) 一种解毒治疗再生障碍性贫血的药物

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20210226

WD01 Invention patent application deemed withdrawn after publication