CN112386542A - Nano skin-care anti-aging mask and preparation method thereof - Google Patents

Nano skin-care anti-aging mask and preparation method thereof Download PDF

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CN112386542A
CN112386542A CN202011367461.4A CN202011367461A CN112386542A CN 112386542 A CN112386542 A CN 112386542A CN 202011367461 A CN202011367461 A CN 202011367461A CN 112386542 A CN112386542 A CN 112386542A
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mask
skin
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aging
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刘懿睿
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Shantou Fengrui Biotechnology Co ltd
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Shantou Fengrui Biotechnology Co ltd
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    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The invention relates to the technical field of skin care masks, and particularly relates to a nano skin care anti-aging mask and a preparation method thereof. A nanometer skin-care anti-aging facial mask comprises a nanometer collagen matrix, a facial mask solution and a facial mask base solution, wherein the nanometer collagen matrix comprises squalene, hyaluronic acid, tocopheryl acetate, nanometer protein solution, an N-isopropyl acrylamide monomer, an initiator and high-purity water; the facial mask liquid comprises xanthan gum, grape seed extract, chitosan solution and levovitamin C; the facial mask base solution comprises Aloe barbadensis leaf essential oil, ethanol water solution, nipagin ester, humectant, antiaging agent, cell growth factor, and whitening agent. The invention has the beneficial effects that: the collagen anti-aging mask is composed of nanofiber essence similar to skin cell structures, and when the collagen anti-aging mask is used, stains separated from the skin can move to one side of a collagen nanofiber layer, so that the problem that the skin is difficult to permeate through cosmetic liquid due to the fact that dirt is retained in a cosmetic liquid layer is solved.

Description

Nano skin-care anti-aging mask and preparation method thereof
Technical Field
The invention relates to the technical field of skin care masks, and particularly relates to a nano skin care anti-aging mask and a preparation method thereof.
Background
With the progress and development of biochemical technology, scientists are making efforts to develop anti-aging products, and using substances with physiological activity as cosmetic raw materials to improve skin aging and relaxation and wrinkles becomes a hot spot, so that the demand of consumers on anti-aging cosmetics is increased, especially the new demand on anti-aging cosmetics such as wrinkle removal, freckle removal, beautiful skin color and the like is increased day by day, and enterprises are promoting various anti-aging skin care products to catch the market hot spot, and the market development is rapid.
Facial masks, one category of skin care products. The most basic and important purpose is to make up the still insufficient cleaning work of makeup removal and face washing, and other maintenance functions such as water replenishing and moisturizing, whitening, anti-aging, grease balancing and the like are realized by matching with other essential components on the basis. The principle of the facial mask is that the facial mask is covered on the face for a short time, so that outside air and pollution are temporarily isolated, the skin temperature is increased, pores of the skin are expanded, sweat gland secretion and metabolism are promoted, the oxygen content of the skin is increased, products of epidermal cell metabolism and accumulated grease substances are favorably removed from the skin, water in the facial mask permeates into the horny layer of the epidermis, the skin becomes soft, and the skin is naturally bright and elastic.
At present, the facial masks sold in the market are various, most of the facial masks take artificially synthesized chemicals as active ingredients, and although the facial masks have remarkable beautifying effect in a short time, the facial masks can cause skin damage due to the residue of a large amount of chemicals, particularly heavy metals after long-term use.
Disclosure of Invention
The invention aims to provide a nano skin-care anti-aging mask, which is mainly used for forming a nano strong-permeability covering film on skin, can effectively permeate the skin through nano essence to enter the deep layer of the skin, supplements the nutrition of the skin, conditions the skin, levels fine lines, repairs the elasticity of the skin and delays aging, and is added with an anti-aging component to effectively inhibit bacteria and resist bacteria, thereby improving the skin-care conditioning use effect of the mask.
The invention also aims to provide a preparation method of the nano skin-care anti-aging mask. The preparation method aims to solve the problems of complex preparation process and high cost of the existing mask.
In order to solve the technical problems, the invention adopts the technical scheme that:
a nanometer skin care anti-aging mask comprises a nanometer collagen matrix, a mask solution and a mask base solution, wherein the nanometer collagen matrix comprises 4-6 parts by weight of squalene, 0.5-1 part by weight of hyaluronic acid, 1-3 parts by weight of tocopherol acetate, 5-18 parts by weight of nanometer protein solution, 10-12 parts by weight of N-isopropyl acrylamide monomer, 0.3-0.4 part by weight of initiator and 90-100 parts by weight of high-purity water; the mask liquid comprises 0.5-0.8 part of xanthan gum, 1-5 parts of grape seed extract, 3-6 parts of chitosan solution and 0.3-5 parts of levovitamin C; the facial mask base solution comprises 2-5 parts of aloe vera leaf essential oil, 60-75 parts of ethanol aqueous solution, 0.2-0.3 part of nipagin ester, 4-8 parts of humectant, 1-2 parts of anti-aging agent, 0.01-4 parts of cell growth factor and 2-4 parts of whitening agent.
Preferably, the humectant is one of sodium polyglutamate, sodium hyaluronate or betaine.
Preferably, the whitening agent is one of phenylethyl resorcinol, algin or arbutin.
A preparation method of a nano skin-care anti-aging mask comprises the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 80-90 ℃, continuously stirring in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, keeping the temperature of the mixed solution in the inert atmosphere and stirring for 25-30min, adding the raw material components of the mask base solution and stirring for 10-15min, and finishing prepolymerization; placing the prepolymerized sample at 25-40 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 2-3 hours to remove unreacted monomers and filter other impurities through a filter, finally placing the swelled nano protein liquid in a mask liquid, stirring for 30-40min, and placing the nano protein liquid in a freeze drying box to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.3-0.6 h according to the proportion, and then adding the nano protein liquid colloid substance prepared in the step S2 and continuously stirring for 2-3 h; pumping the whole into a high-pressure homogenizer for homogenizing for 1.5 to 2.5 hours, wherein the homogenizing pressure is 400-2Injecting the mixture into a mask-shaped mold after vacuum defoaming, standing at room temperature for 20-25min, and sterilizing and packaging to obtain the nanometer skin-care anti-aging mask.
Preferably, the preparation method of the aloe vera leaf essential oil comprises the following steps: drying the aloe vera leaves in the ratio for 2 hours in a vacuum environment, taking out and refrigerating for 0.5-1 hour, then crushing by a crusher, sieving by a sieve of 100 plus 150 meshes to obtain aloe vera leaf powder, placing the aloe vera leaf powder in a fine heat extractor, adding pure water, heating, distilling and purifying for 6-8 hours, and collecting to obtain the aloe vera leaf essential oil.
Compared with the prior art, the invention has the beneficial effects that: the invention provides a collagen anti-aging mask which is composed of nanofiber essence similar to a skin cell structure, when the collagen anti-aging mask is used, stains separated from the skin can move to one side of a collagen nanofiber layer, and therefore the problem that cosmetic liquid is difficult to permeate the skin due to the fact that dirt is retained in a cosmetic liquid layer is solved; the effects of various natural plant essences and synergistic effects are strongest, so that the skin is not damaged or injured, the skin-care cream has good repairing and anti-aging effects, and the effects of toxin expelling, purification, inflammation diminishing, bacteriostasis, moisture retention, whitening and the like are achieved; the invention does not contain preservative and chemical additive, is safe and has no side effect.
Detailed Description
The present invention will be further described with reference to the following examples.
The first embodiment: a nanometer skin-care anti-aging mask comprises 4 parts of squalene, 0.5 part of hyaluronic acid, 3 parts of tocopherol acetate, 5 parts of nano protein liquid, 10 parts of N-isopropylacrylamide monomer, 0.3 part of initiator and 95 parts of high-purity water by weight, a mask liquid consisting of 0.8 part of xanthan gum, 4 parts of grape seed extract, 3 parts of chitosan solution and 1 parts of levorotatory vitamin c, and a mask base liquid consisting of 2 parts of aloe barbadensis leaf essential oil, 60 parts of ethanol aqueous solution, 0.2 part of nipagin ester, 4 parts of sodium hyaluronate, 2 parts of anti-aging agent, 0.5 part of cell growth factor and 2 parts of phenethyl resorcinol.
A preparation method of a nano skin-care anti-aging mask comprises the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 80 ℃, continuously stirring in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, keeping the temperature of the mixed solution in the inert atmosphere and stirring for 30min, adding the raw material components of the mask base solution, and stirring for 15min to complete prepolymerization; placing the prepolymerized sample at 30 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 3 hours to remove unreacted monomers and filter other impurities through a filter, finally placing the swollen nano protein liquid into the mask liquid, stirring for 30-40min, and placing the nano protein liquid in a freeze drying oven to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.3 hour according to the proportion, adding the nano protein liquid colloid substance prepared in the step S2, and continuously stirring for 2 hours; pumping the mixture into a high-pressure homogenizer for homogenization for 2 hours, wherein the homogenization pressure is 400kg/cm2And after vacuum defoaming, injecting the mixture into a mask-shaped mold, standing at room temperature for 25min, and sterilizing and packaging to obtain the nano skin-care anti-aging mask.
Second embodiment:
a nanometer skin-care anti-aging mask comprises a nanometer collagen matrix, a mask liquid and a mask base liquid, wherein the nanometer collagen matrix comprises 6 parts by weight of squalene, 1 part by weight of hyaluronic acid, 1 part by weight of tocopheryl acetate, 10 parts by weight of nanometer protein liquid, 12 parts by weight of N-isopropylacrylamide monomer, 0.3 part by weight of initiator and 90 parts by weight of high-purity water, the mask liquid comprises 0.8 part by weight of xanthan gum, 5 parts by weight of grape seed extract, 6 parts by weight of chitosan solution and 0.3 part by weight of levorotatory vitamin c, and the mask base liquid comprises 2 parts by weight of aloe barbadensis leaf essential oil, 75 parts by weight of ethanol aqueous solution, 0.3 part by weight of nipagin ester, 4 parts by weight of betaine, 2 parts by weight of anti-aging agent, 4 parts by weight.
A preparation method of a nano skin-care anti-aging mask comprises the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 85 ℃, continuously stirring in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, keeping the temperature of the mixed solution in the inert atmosphere and stirring for 25min, adding the raw material components of the mask base solution, and stirring for 15min to complete prepolymerization; placing the prepolymerized sample at 40 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 3 hours to remove unreacted monomers and filter other impurities through a filter, finally placing the swollen nano protein liquid into the mask liquid, stirring for 30-40min, and placing the nano protein liquid in a freeze drying oven to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.6 hour according to the proportion, adding the nano protein liquid colloid substance prepared in the step S2, and continuously stirring for 3 hours; pumping the mixture into a high-pressure homogenizer for homogenization for 2.5 hours, wherein the homogenization pressure is 600kg/cm2And after vacuum defoaming, injecting the mixture into a mask-shaped mold, standing at room temperature for 25min, and sterilizing and packaging to obtain the nano skin-care anti-aging mask.
The third embodiment:
a nanometer skin-care anti-aging mask comprises a nanometer collagen matrix, a mask liquid and a mask base liquid, wherein the nanometer collagen matrix comprises 6 parts by weight of squalene, 1 part by weight of hyaluronic acid, 3 parts by weight of tocopherol acetate, 18 parts by weight of nanometer protein liquid, 11 parts by weight of N-isopropylacrylamide monomer, 0.4 part by weight of initiator and 100 parts by weight of high-purity water, the mask liquid comprises 0.8 part by weight of xanthan gum, 2 parts by weight of grape seed extract, 6 parts by weight of chitosan solution and 75 parts by weight of levorotatory vitamin c5, and the mask base liquid comprises 5 parts by weight of aloe barbadensis leaf essential oil, 75 parts by weight of ethanol aqueous solution, 0.3 part by weight of nipagin ester, 8 parts by weight of sodium hyaluronate, 1.5 parts by weight of anti-aging agent, 3.5 parts by.
A preparation method of a nano skin-care anti-aging mask comprises the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 80 ℃, continuously stirring in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, keeping the temperature of the mixed solution in the inert atmosphere and stirring for 28min, adding the raw material components of the mask base solution, and stirring for 10min to complete prepolymerization; placing the prepolymerized sample at 30 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 2.5 hours to remove unreacted monomers and filter other impurities through a filter, finally placing the swelled nano protein liquid in a mask liquid, stirring for 30min, and placing the nano protein liquid in a freeze drying oven to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.3 hour according to the proportion, adding the nano protein liquid colloid substance prepared in the step S2, and continuously stirring for 2 hours; pumping the mixture into a high-pressure homogenizer for homogenization for 2.5 hours, wherein the homogenization pressure is 600kg/cm2And after vacuum defoaming, injecting the mixture into a mask-shaped mold, standing at room temperature for 25min, and sterilizing and packaging to obtain the nano skin-care anti-aging mask.
The fourth embodiment:
a nanometer skin-care anti-aging mask comprises a nanometer collagen matrix, a mask liquid and a mask base liquid, wherein the nanometer collagen matrix comprises, by weight, 5 parts of squalene, 1 part of hyaluronic acid, 3 parts of tocopherol acetate, 5 parts of nanometer protein liquid, 10 parts of N-isopropylacrylamide monomer, 0.3 part of initiator and 98 parts of high-purity water, the mask liquid comprises 0.8 part of xanthan gum, 5 parts of grape seed extract, 6 parts of chitosan solution and 8 parts of levorotatory vitamin c5, and the mask base liquid comprises 4 parts of aloe vera leaf essential oil, 75 parts of ethanol water solution, 0.3 part of nipagin ester, 7 parts of sodium polyglutamate, 2 parts of anti-aging agent, 0.08 part of cell growth factor and 4 parts of alginate jelly.
A preparation method of a nano skin-care anti-aging mask comprises the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 90 ℃, stirring continuously in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, keeping the mixed solution in the inert atmosphere for stirring for 25min, adding the raw material components of the mask base solution, and stirring for 10min to complete prepolymerization; placing the prepolymerized sample at 25 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 3 hours to remove unreacted monomers and filter other impurities through a filter, finally placing the swollen nano protein liquid into the mask liquid, stirring for 40min, and placing the nano protein liquid in a freeze drying oven to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.6 hour according to the proportion, adding the nano protein liquid colloid substance prepared in the step S2, and continuously stirring for 2 hours; pumping the mixture into a high-pressure homogenizer for homogenizing for 1.5 hours at a homogenizing pressure of 500kg/cm2And after vacuum defoaming, injecting the mixture into a mask-shaped mold, standing the mixture at room temperature for 20min, and sterilizing and packaging the mixture to obtain the nano skin-care anti-aging mask.
The facial mask essences in examples 1, 2, 3 and 4 are taken, two types of facial mask essences sold in the market are selected randomly as a comparison group 1 and a comparison group 2 according to a conventional in vitro model DPPH method, and the absorbance reduction value is measured, so that the oxidation resistance of active substances in the facial mask liquid can be evaluated because the linear relation between the degree of diminishing the absorbance and the degree of removing free radicals is formed.
Product(s) DPPH clearance% Product(s) DPPH clearance%
First embodiment 87.5 Second embodiment 89.4
Third embodiment 79.9 Fourth embodiment 81.2
Comparative group 1 62.6 Comparative group 2 71.4
Table 1: antioxidant capacity comparison table
From the test results, after 200 volunteers in clinical follow-up experiments use the facial masks of the embodiments 1 to 5, the skin elasticity recovery effect is obvious, the skin becomes firm, smooth and fine, and the skin problems such as fine lines, skin sagging and the like are well solved.
It should be understood that the above-described embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.

Claims (5)

1. A nanometer skin-care anti-aging mask is characterized in that: the nano-collagen matrix comprises, by weight, 4-6 parts of squalene, 0.5-1 part of hyaluronic acid, 1-3 parts of tocopherol acetate, 5-18 parts of nano-protein solution, 10-12 parts of N-isopropylacrylamide monomer, 0.3-0.4 part of initiator and 90-100 parts of high-purity water; the mask liquid comprises 0.5-0.8 part of xanthan gum, 1-5 parts of grape seed extract, 3-6 parts of chitosan solution and 0.3-5 parts of levovitamin C; the facial mask base solution comprises 2-5 parts of aloe vera leaf essential oil, 60-75 parts of ethanol aqueous solution, 0.2-0.3 part of nipagin ester, 4-8 parts of humectant, 1-2 parts of anti-aging agent, 0.01-4 parts of cell growth factor and 2-4 parts of whitening agent.
2. The nano skin-care anti-aging mask as claimed in claim 1, wherein the moisturizing agent is one of sodium polyglutamate, sodium hyaluronate or betaine.
3. The nano skin-care anti-aging mask as claimed in claim 1, wherein the whitening agent is one of phenylethyl resorcinol, algin or arbutin.
4. A preparation method of a nano skin-care anti-aging mask is characterized by comprising the following steps:
s1, weighing an initiator, putting the initiator into a reactor, adding high-purity water for dissolving, adding an N-isopropylacrylamide monomer, stirring until the monomer is dissolved, adding hyaluronic acid and tocopheryl acetate, stirring uniformly, adding squalene and a nano protein solution, and stirring uniformly to obtain a suspension;
s2, introducing inert gas into the suspension obtained in the step S1 for exhausting, keeping the suspension in an inert atmosphere, heating to 80-90 ℃, continuously stirring in the heating process, quickly adding a cross-linking agent after the squalene and the nano protein liquid are fully dissolved to obtain a mixed solution, continuously stirring the mixed solution in the inert atmosphere at a constant temperature for 25-30min, adding the raw material components of the mask base solution, and stirring for 10-15min to complete prepolymerization; placing the prepolymerized sample at 25-40 ℃, continuing to carry out freeze polymerization for 15 hours, after the reaction is finished, soaking the obtained hydrogel in deionized water at room temperature for 24 hours, replacing the deionized water every 2-3 hours to remove unreacted monomers and filter other impurities, finally placing the swelled nano protein liquid in the mask liquid, stirring for 30-40min, and placing the nano protein liquid in a freeze drying box to dry to constant weight;
s3, uniformly stirring the components in the mask liquid in a stirring kettle at room temperature for 0.3-0.6 h according to the proportion, and then adding the nano protein liquid colloid substance prepared in the step S2 and continuously stirring for 2-3 h; pumping the whole into a high-pressure homogenizer for homogenizing for 1.5 to 2.5 hours, wherein the homogenizing pressure is 400-2Injecting the mixture into a mask-shaped mold after vacuum defoaming, standing at room temperature for 20-25min, and sterilizing and packaging to obtain the nanometer skin-care anti-aging mask.
5. The method for preparing the nano skin-care anti-aging mask as claimed in claim 4, wherein the preparation steps of the aloe vera leaf essential oil are as follows: drying the aloe vera leaves in the ratio for 2h in a vacuum environment, taking out and refrigerating for 0.5-1h, then crushing by a crusher, sieving by a sieve of 100 plus 150 meshes to obtain aloe vera leaf powder, placing the aloe vera leaf powder in a fine heat extractor, adding distilled water, heating for 8h, and collecting to obtain the aloe vera leaf essential oil.
CN202011367461.4A 2020-11-27 2020-11-27 Nano skin-care anti-aging mask and preparation method thereof Withdrawn CN112386542A (en)

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