CN112370590B - Limb local administration and dialysis device and application thereof - Google Patents
Limb local administration and dialysis device and application thereof Download PDFInfo
- Publication number
- CN112370590B CN112370590B CN202011252415.XA CN202011252415A CN112370590B CN 112370590 B CN112370590 B CN 112370590B CN 202011252415 A CN202011252415 A CN 202011252415A CN 112370590 B CN112370590 B CN 112370590B
- Authority
- CN
- China
- Prior art keywords
- box body
- dialysis
- connecting seat
- tube
- dialysate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000502 dialysis Methods 0.000 title claims abstract description 117
- 230000007246 mechanism Effects 0.000 claims abstract description 136
- 239000008280 blood Substances 0.000 claims abstract description 129
- 210000004369 blood Anatomy 0.000 claims abstract description 129
- 239000012528 membrane Substances 0.000 claims abstract description 44
- 238000012544 monitoring process Methods 0.000 claims abstract description 35
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 17
- 229960002897 heparin Drugs 0.000 claims description 17
- 229920000669 heparin Polymers 0.000 claims description 17
- 238000011200 topical administration Methods 0.000 claims description 9
- 239000004033 plastic Substances 0.000 claims description 5
- 229920003023 plastic Polymers 0.000 claims description 5
- 238000009434 installation Methods 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 24
- 230000000694 effects Effects 0.000 abstract description 14
- 238000000034 method Methods 0.000 abstract description 13
- 230000017531 blood circulation Effects 0.000 abstract description 12
- 230000008569 process Effects 0.000 abstract description 10
- 210000003414 extremity Anatomy 0.000 description 80
- 230000002861 ventricular Effects 0.000 description 10
- 229940079593 drug Drugs 0.000 description 9
- 210000003462 vein Anatomy 0.000 description 8
- 210000000709 aorta Anatomy 0.000 description 7
- 238000010586 diagram Methods 0.000 description 7
- 238000012377 drug delivery Methods 0.000 description 7
- 206010031252 Osteomyelitis Diseases 0.000 description 6
- 201000011510 cancer Diseases 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 239000011253 protective coating Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 208000008960 Diabetic foot Diseases 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000011241 protective layer Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- -1 polydimethylsiloxane Polymers 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 125000003003 spiro group Chemical group 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- KXGFMDJXCMQABM-UHFFFAOYSA-N 2-methoxy-6-methylphenol Chemical compound [CH]OC1=CC=CC([CH])=C1O KXGFMDJXCMQABM-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000025962 Crush injury Diseases 0.000 description 2
- 206010050702 Crush syndrome Diseases 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 238000002266 amputation Methods 0.000 description 2
- 230000003872 anastomosis Effects 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- XXBDWLFCJWSEKW-UHFFFAOYSA-N dimethylbenzylamine Chemical compound CN(C)CC1=CC=CC=C1 XXBDWLFCJWSEKW-UHFFFAOYSA-N 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000003822 epoxy resin Substances 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 239000011812 mixed powder Substances 0.000 description 2
- 239000011259 mixed solution Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 239000005011 phenolic resin Substances 0.000 description 2
- 229920001568 phenolic resin Polymers 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 229920000647 polyepoxide Polymers 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 239000004408 titanium dioxide Substances 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- IFPMZBBHBZQTOV-UHFFFAOYSA-N 1,3,5-trinitro-2-(2,4,6-trinitrophenyl)-4-[2,4,6-trinitro-3-(2,4,6-trinitrophenyl)phenyl]benzene Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C(C=2C(=C(C=3C(=CC(=CC=3[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O)C(=CC=2[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O)=C1[N+]([O-])=O IFPMZBBHBZQTOV-UHFFFAOYSA-N 0.000 description 1
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 206010004053 Bacterial toxaemia Diseases 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 208000002682 Hyperkalemia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 102000036675 Myoglobin Human genes 0.000 description 1
- 108010062374 Myoglobin Proteins 0.000 description 1
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000033626 Renal failure acute Diseases 0.000 description 1
- 206010063837 Reperfusion injury Diseases 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 206010040070 Septic Shock Diseases 0.000 description 1
- 208000013222 Toxemia Diseases 0.000 description 1
- 201000011040 acute kidney failure Diseases 0.000 description 1
- 208000012998 acute renal failure Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000009640 blood culture Methods 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000022900 cardiac muscle contraction Effects 0.000 description 1
- POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002906 medical waste Substances 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000107 myocyte Anatomy 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000036303 septic shock Effects 0.000 description 1
- 230000008337 systemic blood flow Effects 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/005—Anatomical parts of the body used as an access side to the body
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention relates to the technical field of medical instruments, in particular to a limb local administration and dialysis device which comprises a fixing mechanism, a limb local administration mechanism, a dialysis mechanism and a monitoring mechanism, wherein the limb local administration mechanism and the dialysis mechanism can be detachably arranged on the fixing mechanism, the monitoring mechanism is fixedly arranged on the fixing mechanism, the monitoring mechanism is matched with the dialysis mechanism, and the fixing mechanism comprises a bottom plate, a vertical plate, a first hook and a second hook. The invention can avoid the situation of wasting medical resources in the using process, can timely find and process when the coiled dialysis membrane is broken, not only can ensure the dialysis effect, but also can prevent the blood loss of a patient, and particularly, can avoid a large amount of dialysate from entering a blood circulation system of the patient to avoid potential safety hazards, is not easy to leak the blood during medicine adding, is convenient to use, and can effectively avoid the phenomenon that a pipeline connected with the dialysate is loosened.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a limb local administration and dialysis device and application thereof.
Background
With frequent occurrence of earthquakes, traffic accidents, landslides and the like, patients with limb crush injury and separation injury are more and more frequent; after limb blood supply is recovered by adopting techniques such as vascular anastomosis and the like, side effects such as hyperkalemia, hypermyoglobinemia and the like can occur, so that life is threatened. However, in other patients, such as diabetic feet, limited malignant tumors of limbs, osteomyelitis, etc., the concentration of the drug administered to the affected area through the intravenous route is too low to have the optimal effect, and the systemic drug concentration is too high, which may affect other organs. If the limb of the patient is extruded for a long time (at normal temperature, more than 6-7 hours), myocyte degeneration and necrosis can be caused, and a large amount of myoglobin, potassium ions, magnesium ions, phosphate radicals, sulfate radicals and non-protein nitrogen are released; after the heavy objects are removed, the toxic substances enter the blood circulation of the whole body, can cause acute renal failure and finally endanger life; i.e. reperfusion injury occurs. Therefore, once a serious limb crush injury is found, emergency incision and decompression are required; even, some patients have suffered from necrosis of the distal limb muscle segment due to mere blockage of a broken blood vessel, etc., and amputation is also performed in order to reduce the effect on the kidney function.
In addition, for the patients with limb fracture, especially the patients with limb fracture with developed muscles, when the limbs of the patients are not well preserved or the patients have a poor diagnosis; after the amputated limb replantation operation is carried out by the vascular anastomosis technology, the physiological and pathological changes similar to the extrusion syndrome can also appear on the whole body. Even if some patients have a timely visit, no replantation is advocated because of abundant muscle of the severed limbs (such as broken thigh).
In addition, diabetes and osteomyelitis are also more and more common; these patients may have bacterial and necrotic tissues entering the blood circulation to produce toxemia, and then have septic shock and death; although a large number of effective antibiotics may be used for treatment at this time, systemic application of such a large number of antibiotics distributes the drug throughout the body and not locally within the affected limb; sometimes, in order to achieve effective drug concentration in local lesions, the drug concentration is often required to be increased, so that other organs are easily damaged; and the treatment effect cannot be achieved even if the concentration is too low, and the antibiotic is easy to generate drug-resistant flora after long-term use. Some studies have shown that some patients have demonstrated blood-borne bacterial kill through blood culture, but the general condition continues to worsen. The heart muscle contraction force can be reduced due to the fact that blood flowing back to the heart through limb blood contains a large amount of cytokines such as TNF, IL6 and IL 8; meanwhile, a plurality of waterfall-like reactions can be stimulated, and a large number of inflammation mediums are expressed to cause secondary injury of tissues and organs of the body.
When a patient with limb malignant tumor is treated clinically, general chemotherapy of an anti-tumor medicament is usually carried out before limb protection of amputation or artificial limb replacement to avoid or reduce tumor emboli from entering general blood circulation, so that tumor metastasis of the pathway is prevented; but the anti-tumor medicine also has obvious influence on the normal tissues of the body. Therefore, the above-mentioned limited lesion treatment difficulties of these limbs are: 1 effective drugs should be distributed only in the affected limb; 2 avoid local toxic substances in the affected limb from flowing into the systemic blood circulation.
The prior Chinese patent with the application number of CN201410621027.2 discloses a limb local administration and dialysis device and application thereof, which comprises an arterial ventricular cavity and a venous ventricular cavity; the arterial ventricle cavity and the venous ventricle cavity are two mutually isolated box bodies, and the arterial ventricle cavity is provided with an arterial blood inlet matched with one end of the aorta, an arterial blood outlet matched with the other end of the aorta and at least one drug administration inlet; the venous chamber cavity is provided with a venous blood inlet matched with the end of a venous limb, a venous blood outlet matched with the proximal side of a vein, a dialysate inlet and a dialysate outlet, a blood coil is arranged in the venous chamber cavity, one end of the blood coil is connected with the venous blood inlet, the other end of the blood coil is connected with the venous blood outlet, the blood coil is of a dialysis tube membrane structure, and when arterial administration is carried out, backflow venous blood is filtered by molecules with specific sizes, so that the medicine for the limb at the affected side is provided, and the medicine is limited to the blood circulation of the affected limb; the harmful substances generated by the affected limb are discharged out of the body, so that the harmful substances do not enter the whole blood circulation, and the purpose of treating the limited lesions of the limb is achieved, but the above patent still has the following problems in the using process:
1) the arterial ventricular cavity and the venous ventricular cavity are integrally designed, so that the arterial ventricular cavity and the venous ventricular cavity are not completely utilized after being used (the arterial ventricular cavity or the venous ventricular cavity is not used) when only local administration or local dialysis is needed, and the arterial ventricular cavity and the venous ventricular cavity are still required to be treated as medical waste after being used, so that medical resources are wasted in the using process;
2) whether the blood coil is broken or not can not be monitored in real time in the using process, the dialysis effect is influenced when the blood coil is broken, blood loss of a patient can also be caused, and particularly, a large amount of dialysate possibly enters a blood circulation system of the patient to cause potential safety hazards;
3) when the medicine is used, the phenomenon of blood leakage often occurs at the medicine feeding inlet during medicine feeding, and the connection between the arterial blood inlet and the arterial blood outlet is inconvenient, so that the use of the medicine is inconvenient;
4) when the venous blood transfusion device is used, the venous blood inlet and the venous blood outlet are inconvenient to connect, and the phenomenon that the pipeline is loosened frequently occurs when the dialysate inlet and the dialysate outlet are connected with the pipeline of dialysate.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a limb local administration and dialysis device and application thereof, which can avoid the situation of medical resource waste in the use process, can timely find and treat a coil-shaped dialysis membrane when the membrane is broken, can ensure the dialysis effect, can prevent blood loss of a patient, and particularly can avoid a large amount of dialysate from entering a blood circulation system of the patient to avoid potential safety hazards, is not easy to leak blood during dosing, is convenient to use, can effectively avoid the phenomenon that a pipeline connected with the dialysate is loosened, and solves the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the utility model provides a limbs part is dosed and dialysis device, includes fixed establishment, limbs part and doses the mechanism, dialyses mechanism and monitoring mechanism, the limbs part dose the mechanism with it all can dismantle to install in to dialyse the mechanism fixed establishment is last, monitoring mechanism fixed mounting is on fixed establishment, just monitoring mechanism with it sets up to dialyse the mechanism and cooperate.
By adopting the technical scheme, the fixing mechanism is arranged, the limb local administration mechanism and the dialysis mechanism can be detachably arranged on the fixing mechanism, and the limb local administration mechanism and the dialysis mechanism are designed in a split manner, so that when only local administration is needed or only local dialysis is needed, the unused limb local administration mechanism or dialysis mechanism can be detached for next use, and the situation that medical resources are wasted in the use process can be avoided; through setting up monitoring mechanism, and cooperate the setting with monitoring mechanism and dialysis mechanism, usable monitoring mechanism is to the broken real time monitoring that carries out of the broken membrane that takes place of the coil pipe form dialysis membrane in the dialysis mechanism, can in time discover and do the processing when the broken membrane takes place for the coil pipe form dialysis membrane, not only can guarantee the dialysis effect, still can prevent patient's blood loss, and the important can avoid a large amount of dislysates to get into among patient's the blood circulation system and stop the potential safety hazard.
Further, fixed establishment includes bottom plate, riser, first couple and second couple, the bottom plate level sets up, the riser is vertical and install fixedly on the upper portion of bottom plate, first couple with the second couple respectively fixed mounting be in on the both sides face of riser, just first couple with the second couple symmetry sets up.
Through adopting above-mentioned technical scheme, the fixed establishment who sets up comprises bottom plate, riser, first couple and second couple for fixed establishment simple structure, convenient to use, it is fixed effectual.
Further, the local mechanism of dosing of limbs includes first box body, first side cap, arterial blood input tube, arterial blood output tube and heparin cap, one side of first box body is reserved has first slot, just the opposite side of first box body is open structure, first box body pass through first slot with first couple cooperatees demountable installation in the upper portion of bottom plate, first side cap is fixed and install sealedly first box body is open structure's one side, arterial blood input tube fixed mounting be in on the one end wall of first box body, just the arterial blood input tube with the inside of first box body is linked together and sets up, arterial blood output tube fixed mounting be in on the other end wall of first box body, just the arterial blood output tube with the inside of first box body is linked together and sets up, heparin cap fixed mounting be in on the lateral surface of first side cap, and the heparin cap is communicated with the inside of the first box body.
Through adopting above-mentioned technical scheme, the heparin cap is used for adding the difficult phenomenon that takes place the blood leakage of medicine, and first box body is used for mixing patient's arterial blood and the medicine that adds, and arterial blood input tube is used for the arterial blood of inputing the patient to the inside of first box body, and arterial blood output tube is used for in the artery of the arterial blood input patient who will mix there is the medicine.
Furthermore, the arterial blood input tube is back to the end part of one end of the first box body is fixedly provided with a first puncture needle, the arterial blood output tube is back to the end part of one end of the first box body is fixedly provided with a second puncture needle, and the first puncture needle and the second puncture needle are externally sleeved with plastic protective caps.
Through adopting above-mentioned technical scheme, the setting up of first pjncture needle and second pjncture needle makes limbs local drug delivery mechanism and patient's aorta connect more conveniently to make the device use more conveniently, all overlap in the outside of first pjncture needle and second pjncture needle and be equipped with the plastics helmet, can prevent that first pjncture needle and second pjncture needle mistake from stabbing medical personnel.
Further, dialysis mechanism includes second box body, second side cap, venous blood input tube, venous blood output tube, coil pipe form dialysis membrane, dislysate input connecting seat, transparent connecting pipe and dislysate output connecting seat, one side of second box body is reserved has the second slot, just the opposite side of second box body is open structure, the second box body pass through the second slot with the second couple cooperatees demountable installation in the upper portion of bottom plate, the second side cap is fixed and install sealedly the second box body is the one side of open structure, venous blood input tube with venous blood output tube all fixed mounting be in on the lateral surface of second side cap, and venous blood input tube with venous blood output tube is close to respectively the both ends setting of second side cap, venous blood input tube's other end fixed mounting has first connecting seat, the other end fixed mounting of venous blood output tube has the second connecting seat, coil pipe form dialysis membrane fixed mounting in the inside middle part of second box body, the one end of coil pipe form dialysis membrane with the one end of venous blood input tube is linked together, just the other end of coil pipe form dialysis membrane with the one end of venous blood output tube is linked together, dislysate input connecting seat fixed mounting is in on the one end wall of second box body, transparent connecting pipe fixed mounting is in on the other end wall of second box body, dislysate output connecting seat fixed mounting in the transparent connecting pipe dorsad the one end tip of second box body, just dislysate output connecting seat with the equal fixed mounting in inside of dislysate input connecting seat has the connector, the connector all with the inside of second box body is linked together, dislysate output connecting seat with the equal spiro union in outside of dislysate input connecting seat has the locking cover, and gaps matched with the locking sleeves are reserved on the side walls of the dialysate output connecting seat and the dialysate input connecting seat.
By adopting the technical scheme, the dialysis mechanism comprises a second box body, a second side cover, a venous blood input tube, a venous blood output tube, a coil-shaped dialysis membrane, a dialysate input connecting seat, a transparent connecting tube and a dialysate output connecting seat, wherein a first connecting seat is fixedly arranged at the other end of the venous blood input tube, a second connecting seat is fixedly arranged at the other end of the venous blood output tube, so that the dialysis mechanism is conveniently connected with the venous end of a patient, in addition, connecting heads are fixedly arranged in the dialysate output connecting seat and the dialysate input connecting seat, are communicated with the inside of the second box body, locking sleeves are screwed on the outer parts of the dialysate output connecting seat and the dialysate input connecting seat, and gaps matched with the locking sleeves are reserved on the side walls of the dialysate output connecting seat and the dialysate input connecting seat, therefore, the pipeline connected with the dialysate can be tightly locked by matching the locking sleeve with the notch, and the phenomenon that the pipeline connected with the dialysate is loosened can be effectively avoided.
Further, the monitoring mechanism comprises a shell, a bottom cover, a controller, a loudspeaker and an opposite emission type photoelectric sensor, the shell is fixedly arranged at one end part of the bottom plate, and the upper part of the shell is reserved with a matching groove in the middle, the bottom cover is fixedly arranged at the bottom of the shell, the controller and the loudspeaker are both fixedly arranged in the shell, the electric control end of the loudspeaker is electrically connected with the control output end of the controller through a control line, a plurality of through holes matched with the horn are also formed on one side wall of the shell, the correlation photoelectric sensor is fixedly arranged on the two side walls of the assembling groove, and the correlation type photoelectric sensors are symmetrically distributed on two sides of the transparent connecting pipe, and the signal output ends of the correlation type photoelectric sensors are electrically connected with the signal input end of the controller through signal lines.
Through adopting above-mentioned technical scheme, the monitoring mechanism who sets up is by the shell, the bottom, a controller, loudspeaker and correlation type photoelectric sensor constitute, usable correlation type photoelectric sensor carries out real-time supervision to the turbidity of the inside dislysate of transparent connecting pipe, when correlation type photoelectric sensor monitors the obvious increase of turbidity of the inside dislysate of transparent connecting pipe (explain that mixed blood in the dislysate, it is broken to explain the coil form dialysis membrane emergence membrane), the controller will send the chimes of doom according to the signal control loudspeaker that uploads correlation type photoelectric sensor this moment, and then remind medical personnel in time to handle the condition that the coil form dialysis membrane emergence membrane is broken, can avoid the emergence accident situation.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of limb replantation treatment.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating the crush syndrome.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating diabetic feet.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating the malignant tumor limited by the limb and the technical field of treating osteomyelitis.
By adopting the technical scheme, the device can treat patients with limb fracture needing to be replanted, can treat patients with extrusion syndrome, can treat diabetic feet, can treat patients with malignant tumors with limited limbs and can treat patients with osteomyelitis, so that the device has a wide application range.
In summary, the invention mainly has the following beneficial effects:
1. according to the invention, by arranging the fixing mechanism, and detachably installing the limb local administration mechanism and the dialysis mechanism on the fixing mechanism, the limb local administration mechanism and the dialysis mechanism are designed in a split manner, when only local administration is needed or only local dialysis is needed, the limb local administration mechanism or the dialysis mechanism which is not used can be detached for next use, so that the device can avoid the situation of wasting medical resources in the use process;
2. according to the invention, by arranging the monitoring mechanism and the dialysis mechanism in a matching manner, the monitoring mechanism can be used for monitoring whether the coiled dialysis membrane in the dialysis mechanism is broken in real time, and the broken coiled dialysis membrane can be found and treated in time when the coiled dialysis membrane is broken, so that the dialysis effect can be ensured, the blood loss of a patient can be prevented, and more importantly, a large amount of dialysate can be prevented from entering a blood circulation system of the patient to avoid potential safety hazards;
3. according to the invention, the arranged limb local drug delivery mechanism consists of the first box body, the first side cover, the arterial blood input tube, the arterial blood output tube and the heparin cap, the heparin cap is used for adding drugs and is not easy to leak blood, meanwhile, the first puncture needle is fixedly arranged at the end part of one end of the arterial blood input tube, which is back to the first box body, and the second puncture needle is fixedly arranged at the end part of one end of the arterial blood output tube, which is back to the first box body, so that the connection between the limb local drug delivery mechanism and the aorta of a patient is more convenient, and the device is more convenient to use;
4. the invention is provided with a dialysis mechanism which comprises a second box body, a second side cover, a venous blood input tube, a venous blood output tube, a coil-shaped dialysis membrane, a dialysate input connecting seat, a transparent connecting tube and a dialysate output connecting seat, wherein the other end of the venous blood input tube is fixedly provided with a first connecting seat, the other end of the venous blood output tube is fixedly provided with a second connecting seat, thereby the dialysis mechanism is conveniently connected with the venous end of a patient, in addition, connecting heads are fixedly arranged in the dialysate output connecting seat and the dialysate input connecting seat, the connecting heads are communicated with the inside of the second box body, locking sleeves are respectively screwed on the outside of the dialysate output connecting seat and the dialysate input connecting seat, and gaps matched with the locking sleeves are reserved on the side walls of the dialysate output connecting seat and the dialysate input connecting seat, therefore, the pipeline connected with the dialysate can be tightly locked by matching the locking sleeve with the notch, and the phenomenon that the pipeline connected with the dialysate is loosened can be effectively avoided.
Drawings
FIG. 1 is a schematic diagram of the construction of an embodiment of a topical administration and dialysis device for a limb;
FIG. 2 is a schematic diagram of another perspective of an embodiment of a topical administration and dialysis device for a limb;
FIG. 3 is a schematic diagram of an exploded configuration of an embodiment of a topical administration and dialysis device for a limb;
FIG. 4 is a schematic diagram of an exploded view from another perspective of an embodiment of a topical administration and dialysis device for a limb;
FIG. 5 is a schematic diagram of the local administration mechanism of the limb of the local administration and dialysis device according to one embodiment;
FIG. 6 is a schematic diagram of the dialysis mechanism of the topical administration to the limb and dialysis device of one embodiment;
FIG. 7 is a schematic cross-sectional view of a dialysis mechanism of an embodiment of a topical administration to a limb and dialysis device;
FIG. 8 is an enlarged schematic view of the detail view A of FIG. 7;
FIG. 9 is a schematic diagram of a monitoring mechanism of the topical administration to the limb and dialysis device according to one embodiment.
In the figure: 1. a fixing mechanism; 2. a limb local drug delivery mechanism; 3. a dialysis mechanism; 4. a monitoring mechanism; 5. a base plate; 6. a vertical plate; 7. a first hook; 8. a second hook; 9. a first case; 10. a first slot; 11. a first side cover; 12. a heparin cap; 13. an arterial blood input tube; 14. a first puncture needle; 15. arterial blood efferent vessels; 16. a second puncture needle; 17. a second box body; 18. a second side cover; 19. a venous blood input tube; 20. venous blood efferent vessels; 21. a first connecting seat; 22. a second connecting seat; 23. a second slot; 24. a coil-shaped dialysis membrane; 25. the dialysate is input into the connecting seat; 26. a dialysate output connecting base; 27. a transparent connecting tube; 28. a locking sleeve; 29. a notch; 30. a connector; 31. a housing; 32. a through hole; 33. assembling the groove; 34. a correlation type photoelectric sensor; 35. a controller; 36. a bottom cover; 37. a horn.
Detailed Description
The present invention is described in further detail below with reference to figures 1-9.
Example 1
A limb local administration and dialysis device is shown in figures 1-2 and comprises a fixing mechanism 1, a limb local administration mechanism 2, a dialysis mechanism 3 and a monitoring mechanism 4, wherein the limb local administration mechanism 2 and the dialysis mechanism 3 are detachably mounted on the fixing mechanism 1, the monitoring mechanism 4 is fixedly mounted on the fixing mechanism 1, and the monitoring mechanism 4 and the dialysis mechanism 3 are matched.
By adopting the technical scheme, the fixing mechanism 1 is arranged, the limb local administration mechanism 2 and the dialysis mechanism 3 can be detachably mounted on the fixing mechanism 1, and the limb local administration mechanism 2 and the dialysis mechanism 3 are designed in a split manner, so that the unused limb local administration mechanism 2 or the unused dialysis mechanism 3 can be detached for next use when only local administration is needed or only local dialysis is needed, and the device can avoid the situation of wasting medical resources in the use process; through setting up monitoring mechanism 4, and with monitoring mechanism 4 and dialysis mechanism 3 setting of cooperateing, usable monitoring mechanism 4 is to the broken real time monitoring that carries out of the broken membrane of the coil pipe form dialysis membrane 24 among the dialysis mechanism 3 that whether takes place of membrane, can in time discover and do the processing when the broken membrane of the coil pipe form dialysis membrane 24 takes place, not only can guarantee the dialysis effect, still can prevent patient's blood loss, and especially important can avoid a large amount of dislysates to get into among patient's the blood circulation system and stop the potential safety hazard.
Preferably, as shown in fig. 1 and 3-4, the fixing mechanism 1 includes a bottom plate 5, a vertical plate 6, a first hook 7 and a second hook 8, the bottom plate 5 is horizontally disposed, the vertical plate 6 is vertically and fixedly installed on the upper portion of the bottom plate 5, the first hook 7 and the second hook 8 are respectively and fixedly installed on two side surfaces of the vertical plate 6, and the first hook 7 and the second hook 8 are symmetrically disposed.
Through adopting above-mentioned technical scheme, the fixed establishment 1 that sets up comprises bottom plate 5, riser 6, first couple 7 and second couple 8 for fixed establishment 1 simple structure, convenient to use, it is fixed effectual.
Preferably, as shown in fig. 1 and 3-5, the local limb drug delivery mechanism 2 includes a first box 9, a first side cover 11, an arterial blood input tube 13, an arterial blood output tube 15 and a heparin cap 12, a first slot 10 is reserved on one side of the first box 9, the other side of the first box 9 is an open structure, the first box 9 is detachably mounted on the upper portion of the bottom plate 5 by matching the first slot 10 with the first hook 7, the first side cover 11 is fixedly and hermetically mounted on one side of the first box 9 which is the open structure, the arterial blood input tube 13 is fixedly mounted on one end wall of the first box 9, the arterial blood input tube 13 is communicated with the inside of the first box 9, the arterial blood output tube 15 is fixedly mounted on the other end wall of the first box 9, and the arterial blood output tube 15 is communicated with the inside of the first box body 9, the heparin cap 12 is fixedly mounted on the outer side surface of the first side cover 11, and the heparin cap 12 is communicated with the inside of the first box body 9.
By adopting the technical scheme, the heparin cap 12 is used for adding medicine and is not easy to leak blood, the first box body 9 is used for mixing arterial blood of a patient and added medicine, the arterial blood input tube 13 is used for inputting arterial blood of the patient into the first box body 9, and the arterial blood output tube 15 is used for inputting the arterial blood mixed with the medicine into the artery of the patient.
Preferably, as shown in fig. 5, a first puncture needle 14 is fixedly installed at an end portion of the arterial blood input tube 13 facing away from the first box body 9, a second puncture needle 16 is fixedly installed at an end portion of the arterial blood output tube 15 facing away from the first box body 9, and plastic protective caps are respectively sleeved outside the first puncture needle 14 and the second puncture needle 16.
By adopting the technical scheme, the arrangement of the first puncture needle 14 and the second puncture needle 16 enables the connection between the local limb drug administration mechanism 2 and the aorta of the patient to be convenient, so that the device is convenient to use, plastic protective caps are sleeved outside the first puncture needle 14 and the second puncture needle 16, and medical staff can be prevented from being punctured by the first puncture needle 14 and the second puncture needle 16 by mistake.
Preferably, as shown in fig. 1, 4 and 6-8, the dialysis mechanism 3 comprises a second box body 17, a second side cover 18, a venous blood input tube 19, a venous blood output tube 20, a coil-shaped dialysis membrane 24, a dialysate input connection seat 25, a transparent connection tube 27 and a dialysate output connection seat 26, a second slot 23 is reserved on one side of the second box body 17, and the other side of the second box body 17 is an open structure, the second box body 17 is detachably mounted on the upper portion of the bottom plate 5 by the second slot 23 matching with the second hook 8, the second side cover 18 is fixedly and hermetically mounted on one side of the open structure of the second box body 17, the venous blood input tube 19 and the venous blood output tube 20 are fixedly mounted on the outer side surface of the second side cover 18, and the venous blood input tube 19 and the venous blood output tube 20 are respectively disposed adjacent to two ends of the second side cover 18, the other end fixed mounting of vein blood input tube 19 has first connecting seat 21, the other end fixed mounting of vein blood output tube 20 has second connecting seat 22, coil form dialysis membrane 24 fixed mounting be in the inside middle part of second box body 17, the one end of coil form dialysis membrane 24 with the one end of vein blood input tube 19 is linked together, just the other end of coil form dialysis membrane 24 with the one end of vein blood output tube 20 is linked together, dislysate input connecting seat 25 fixed mounting be in on the one end wall of second box body 17, transparent connecting tube 27 fixed mounting be in on the other end wall of second box body 17, dislysate output connecting seat 26 fixed mounting be in transparent connecting tube 27 dorsad the one end tip of second box body 17, just dislysate output connecting seat 26 with the inside of dislysate input connecting seat 25 all fixed mounting have connector 30, connector 30 all with the inside of second box body 17 is linked together, dialysate output connecting seat 26 with the equal spiro union in outside of dialysate input connecting seat 25 has lock sleeve 28, just dialysate output connecting seat 26 with all reserve on the lateral wall of dialysate input connecting seat 25 have with lock sleeve 28 matched with breach 29.
Through adopting the above technical scheme, the dialysis mechanism 3 that sets up is by second box body 17, second side cap 18, venous blood input tube 19, venous blood output tube 20, coil form dialysis membrane 24, dislysate input connecting seat 25, transparent connecting pipe 27 and dislysate output connecting seat 26 constitute, there is first connecting seat 21 at venous blood input tube 19's other end fixed mounting simultaneously, there is second connecting seat 22 at venous blood output tube 20's other end fixed mounting, thereby it is more convenient to make dialysis mechanism 3 and patient's venous end be connected, in addition, still equal fixed mounting has connector 30 in the inside of dislysate output connecting seat 26 and dislysate input connecting seat 25, connector 30 all is linked together with the inside of second box body 17, still there is locking cover 28 in the equal spiro union in the outside of dislysate output connecting seat 26 and dislysate input connecting seat 25, and all reserve on the lateral wall of dislysate output connecting seat 26 and dislysate input connecting seat 25 and have breach 29 with locking cover 28 matched with Therefore, the locking sleeve 28 can be matched with the notch 29 to tightly lock the pipeline connected with the dialysate, and the phenomenon that the pipeline connected with the dialysate is loosened can be effectively avoided.
Preferably, as shown in fig. 2, 4 and 9, the monitoring mechanism 4 includes a housing 31, a bottom cover 36, a controller 35, a speaker 37 and an opposite-type photoelectric sensor 34, the housing 31 is fixedly mounted at an end of the bottom plate 5, an assembling slot 33 is reserved in the middle of the upper portion of the housing 31, the bottom cover 36 is fixedly mounted at the bottom of the housing 31, the controller 35 and the speaker 37 are both fixedly mounted inside the housing 31, an electric control end of the speaker 37 is electrically connected to a control output end of the controller 35 through a control line, a plurality of through holes 32 matched with the speaker 37 are further formed on a side wall of the housing 31, the opposite-type photoelectric sensor 34 is fixedly mounted on two side walls of the assembling slot 33, the opposite-type photoelectric sensor 34 is symmetrically distributed on two sides of the transparent connecting pipe 27, and a signal output end of the opposite-type photoelectric sensor 34 is connected to a signal output end of the controller 35 through a signal line The input terminal is electrically connected.
Through adopting above-mentioned technical scheme, the monitoring mechanism 4 that sets up is by shell 31, bottom 36, controller 35, loudspeaker 37 and to shooting type photoelectric sensor 34 constitute, usable shooting type photoelectric sensor 34 carries out real-time supervision to the turbidity of the inside dislysate of transparent connecting pipe 27, when shooting type photoelectric sensor 34 monitors the turbidity of the inside dislysate of transparent connecting pipe 27 and obviously increases (illustrate mixed blood in the dislysate, it is broken to illustrate 24 emergence membranes of coil form dialysis membrane), controller 35 will send the chimes of doom according to the signal control loudspeaker 37 that uploads of shooting type photoelectric sensor 34 this moment, and then remind medical personnel in time to handle the condition that 24 emergence membranes of coil form dialysis membrane are broken, can avoid taking place the unexpected condition.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of limb replantation treatment.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating the crush syndrome.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating diabetic feet.
The invention also provides application of the limb local administration and dialysis device, which is applied to the technical field of treating the malignant tumor limited by the limb and the technical field of treating osteomyelitis.
By adopting the technical scheme, the device can treat patients with limb fracture needing to be replanted, can treat patients with extrusion syndrome, can treat diabetic feet, can treat patients with malignant tumors with limited limbs and can treat patients with osteomyelitis, so that the device has a wide application range.
It should be noted that, in this embodiment, the controller 35 may be a novel 8-pin 8-bit high-performance microcontroller with a model number of PIC12F675 and manufactured by Microchip company, and the microcontroller is provided with μ P monitoring, 4-channel 10-bit a/D conversion, 256B RAM, 256B EEPROM, and 1kX 14-bit Flash program memory, and has a working voltage of 2.0-5.5V and a speed of 20 MHz; the correlation type photoelectric sensor 34 is composed of an infrared light emitting diode and an infrared photosensitive diode, and the principle that the turbidity of the dialysate inside the transparent connecting pipe 27 is detected to be obviously increased is that the light intensity received by the infrared photosensitive diode and emitted by the infrared light emitting diode is obviously weakened, so that the signal of the correlation type photoelectric sensor 34 is weaker.
Example 2
The difference from the embodiment 1 is that the surface of the fixing mechanism 1 is further provided with a protective layer, and the protective layer is prepared by the following method:
weighing the following raw materials in parts by weight: 20-30 parts of epoxy resin, 8-12 parts of calcium carbonate powder, 10-12 parts of nano silver powder, 12-16 parts of phenolic resin, 8-10 parts of titanium dioxide powder, 8-10 parts of acrylic emulsion, 2-4 parts of alcohol ester dodeca, 2-4 parts of BDMA, 1-3 parts of polydimethylsiloxane and 30-50 parts of water;
s1, adding weighed alcohol ester twelve, BDMA, polydimethylsiloxane and ethanol into a stirrer, and stirring for 24-30min at the stirring speed of 600-800r/min to obtain a mixed solution;
s2, adding epoxy resin, calcium carbonate powder, nano silver powder, phenolic resin and titanium dioxide powder into a grinder to be ground until the particle diameter of the material is not more than 20um, so as to prepare a mixed powder material;
s3, adding the mixed solution prepared in the step S1, the mixed powder material prepared in the step S2 and acrylic emulsion into a reaction kettle, stirring for 20-30min, setting the stirring speed of the reaction kettle to be 800-1000r/min and the temperature to be 80-100 ℃, and thus obtaining the protective coating;
s4, cleaning and airing the surface of the fixing mechanism 1, and then uniformly spraying the protective coating prepared in the step S3 on the aired surface of the fixing mechanism 1 by using a high-pressure sprayer spray gun to form a coating film;
and S5, drying the fixing mechanism 1 sprayed with the protective coating in the step S4 in a drying chamber at the drying temperature of 80-100 ℃ for 20-30min, and thus obtaining the protective layer on the surface of the fixing mechanism 1.
The distribution of bacteria on the surface of the fixing means 1 observed under a microscope after the fixing means 1 of example 1-2 is placed in a bacteria culture chamber and left under the same conditions for 5 days is recorded as follows:
| examples | Record the results |
| Example 1 | The surface of the fixing mechanism 1 is distributed with a large number of bacterial colonies |
| Example 2 | The surface of the fixing means 1 is hardly distributed with colonies |
The result recorded from the table above is comparatively analyzed, and it can be seen that embodiment 2 is the most preferred embodiment, by adopting the above technical scheme, the process for preparing the protective coating is simple in steps and easy to implement, the prepared protective coating has moderate viscosity, is not easy to delaminate, is convenient to spray, does not generate bubbles, is fully combined with each component, and has good comprehensive performance, so that the protective coating can form a good coating after spraying, is not easy to generate cracks, and has a good film forming effect, the prepared protective layer has good corrosion resistance, skid resistance and bacteria resistance, has good adhesiveness and is not easy to fall off, the corrosion resistance, skid resistance and bacteria resistance of the fixing mechanism 1 can be effectively improved, and more importantly, the device can prevent the use from being influenced by a large amount of bacteria on the surface of the fixing mechanism 1 when in use.
The working principle is as follows: according to the limb local administration and dialysis device, the fixing mechanism 1 is arranged, the limb local administration mechanism 2 and the dialysis mechanism 3 can be detachably mounted on the fixing mechanism 1, and the limb local administration mechanism 2 and the dialysis mechanism 3 are designed in a split manner, so that when only local administration is needed or only local dialysis is needed, the limb local administration mechanism 2 or the dialysis mechanism 3 which is not used can be detached for next use, and the situation that medical resources are wasted in the use process can be avoided;
by arranging the monitoring mechanism 4 and matching the monitoring mechanism 4 with the dialysis mechanism 3, the monitoring mechanism 4 can be used for monitoring whether the coiled dialysis membrane 24 in the dialysis mechanism 3 is broken in real time, and when the coiled dialysis membrane 24 is broken, the broken membrane can be found and treated in time, so that the dialysis effect can be ensured, the blood loss of a patient can be prevented, and more importantly, a large amount of dialysate can be prevented from entering a blood circulation system of the patient to avoid potential safety hazards;
the arranged limb local drug delivery mechanism 2 consists of a first box body 9, a first side cover 11, an arterial blood input tube 13, an arterial blood output tube 15 and a heparin cap 12, wherein the heparin cap 12 is used for adding drugs and is not easy to leak blood, meanwhile, a first puncture needle 14 is fixedly arranged at the end part of the arterial blood input tube 13, which is back to the first box body 9, and a second puncture needle 16 is fixedly arranged at the end part of the arterial blood output tube 15, which is back to the first box body 9, so that the limb local drug delivery mechanism 2 is more convenient to connect with the aorta of a patient, and the device is more convenient to use;
the dialysis mechanism 3 comprises a second box body 17, a second side cover 18, a venous blood input tube 19, a venous blood output tube 20, a coil-shaped dialysis membrane 24, a dialysate input connecting seat 25, a transparent connecting tube 27 and a dialysate output connecting seat 26, wherein a first connecting seat 21 is fixedly arranged at the other end of the venous blood input tube 19, a second connecting seat 22 is fixedly arranged at the other end of the venous blood output tube 20, so that the dialysis mechanism 3 is conveniently connected with the venous end of a patient, in addition, connectors 30 are fixedly arranged in the dialysate output connecting seat 26 and the dialysate input connecting seat 25, the connectors 30 are communicated with the inside of the second box body 17, locking sleeves 28 are screwed at the outer parts of the dialysate output connecting seat 26 and the dialysate input connecting seat 25, and notches 29 matched with the locking sleeves 28 are reserved on the side walls of the dialysate output connecting seat 26 and the dialysate input connecting seat 25, therefore, the locking sleeve 28 can be matched with the notch 29 to tightly lock the pipeline connected with the dialysate, and the phenomenon that the pipeline connected with the dialysate is loosened can be effectively avoided.
The using method comprises the following steps: when in use, the first puncture needle 14 and the second puncture needle 16 are respectively connected with the near end and the far end of the aorta of a patient, and then a syringe is matched with the heparin cap 12 to add therapeutic drugs into the first box body 9; connect the drain pipe on the liquid bag of dislysate on the inside connector 30 of dislysate input connecting seat 25 and with the locking of lock sleeve 28, connect the liquid return pipe on the liquid bag of dislysate on the inside connector 30 of dislysate output connecting seat 26 and with the locking of lock sleeve 28, can connect the power pump on the drain pipe on the liquid bag of dislysate in order to guarantee the dialysis effect, utilize first connecting seat 21 and second connecting seat 22 to be connected with patient's vein near-end and vein distal end respectively, can install the power pump additional between first connecting seat 21 and vein blood input tube 19 in order to guarantee the dialysis effect.
The parts not involved in the present invention are the same as or can be implemented by the prior art. The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.
Claims (2)
1. A topical administration and dialysis device for a limb, comprising: the device comprises a fixing mechanism (1), a limb local administration mechanism (2), a dialysis mechanism (3) and a monitoring mechanism (4), wherein the limb local administration mechanism (2) and the dialysis mechanism (3) can be detachably mounted on the fixing mechanism (1), the monitoring mechanism (4) is fixedly mounted on the fixing mechanism (1), and the monitoring mechanism (4) is matched with the dialysis mechanism (3);
the fixing mechanism (1) comprises a bottom plate (5), a vertical plate (6), a first hook (7) and a second hook (8), wherein the bottom plate (5) is horizontally arranged, the vertical plate (6) is vertically and fixedly arranged on the upper part of the bottom plate (5), the first hook (7) and the second hook (8) are respectively and fixedly arranged on two side surfaces of the vertical plate (6), and the first hook (7) and the second hook (8) are symmetrically arranged;
the local administration mechanism (2) for the limbs comprises a first box body (9), a first side cover (11), an arterial blood input tube (13), an arterial blood output tube (15) and a heparin cap (12), wherein a first slot (10) is reserved on one side of the first box body (9), the other side of the first box body (9) is of an open structure, the first box body (9) is matched with and detachably mounted on the upper portion of the bottom plate (5) through the first slot (10) and the first hook (7), the first side cover (11) is fixedly and hermetically mounted on one side of the open structure of the first box body (9), the arterial blood input tube (13) is fixedly mounted on one end wall of the first box body (9), the arterial blood input tube (13) is communicated with the inside of the first box body (9), the arterial blood output tube (15) is fixedly mounted on the other end wall of the first box body (9), the arterial blood outlet pipe (15) is communicated with the inside of the first box body (9), the heparin cap (12) is fixedly arranged on the outer side surface of the first side cover (11), and the heparin cap (12) is communicated with the inside of the first box body (9);
dialysis mechanism (3) includes second box body (17), second side cap (18), venous blood input tube (19), venous blood output tube (20), coil form dialysis membrane (24), dislysate input connecting seat (25), dislysate output connecting seat (26) and transparent connecting pipe (27), second slot (23) are reserved to one side of second box body (17), just the opposite side of second box body (17) is open structure, second box body (17) pass through second slot (23) with second couple (8) cooperate demountable installation in the upper portion of bottom plate (5), second side cap (18) are fixed and install sealedly second box body (17) are open structure's one side, venous blood input tube (19) with venous blood output tube (20) all fixed mounting be in on the lateral surface of second side cap (18), the venous blood input tube (19) and the venous blood output tube (20) are respectively arranged at two ends adjacent to the second side cover (18), a first connecting seat (21) is fixedly arranged at the other end of the venous blood input tube (19), a second connecting seat (22) is fixedly arranged at the other end of the venous blood output tube (20), the coiled dialysis membrane (24) is fixedly arranged at the middle part of the interior of the second box body (17), one end of the coiled dialysis membrane (24) is communicated with one end of the venous blood input tube (19), the other end of the coiled dialysis membrane (24) is communicated with one end of the venous blood output tube (20), the dialysate input connecting seat (25) is fixedly arranged on one end wall of the second box body (17), and the transparent connecting tube (27) is fixedly arranged on the other end wall of the second box body (17), the dialysate output connecting seat (26) is fixedly installed at one end part, back to the second box body (17), of the transparent connecting pipe (27), connectors (30) are fixedly installed inside the dialysate output connecting seat (26) and the dialysate input connecting seat (25), the connectors (30) are communicated with the inside of the second box body (17), locking sleeves (28) are screwed outside the dialysate output connecting seat (26) and the dialysate input connecting seat (25), and notches (29) matched with the locking sleeves (28) are reserved on the side walls of the dialysate output connecting seat (26) and the dialysate input connecting seat (25);
the monitoring mechanism (4) comprises a shell (31), a bottom cover (36), a controller (35), a loudspeaker (37) and an opposite-radiation type photoelectric sensor (34), the shell (31) is fixedly installed at one end of the bottom plate (5), an assembling groove (33) is reserved in the middle of the upper portion of the shell (31), the bottom cover (36) is fixedly installed at the bottom of the shell (31), the controller (35) and the loudspeaker (37) are both fixedly installed inside the shell (31), an electric control end of the loudspeaker (37) is electrically connected with a control output end of the controller (35) through a control line, a plurality of through holes (32) matched with the loudspeaker (37) are further formed in one side wall of the shell (31), the opposite-radiation type photoelectric sensor (34) is fixedly installed on two side walls of the assembling groove (33), and the correlation type photoelectric sensors (34) are symmetrically distributed on two sides of the transparent connecting pipe (27), and the signal output ends of the correlation type photoelectric sensors (34) are electrically connected with the signal input end of the controller (35) through signal lines.
2. The topical administration and dialysis device to a limb of claim 1, wherein: arterial blood input tube (13) dorsad the one end tip fixed mounting of first box body (9) has first pjncture needle (14), arterial blood output tube (15) dorsad the one end tip fixed mounting of first box body (9) has second pjncture needle (16), first pjncture needle (14) with the outside of second pjncture needle (16) all is overlapped and is equipped with the plastics helmet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011252415.XA CN112370590B (en) | 2020-11-11 | 2020-11-11 | Limb local administration and dialysis device and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011252415.XA CN112370590B (en) | 2020-11-11 | 2020-11-11 | Limb local administration and dialysis device and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112370590A CN112370590A (en) | 2021-02-19 |
| CN112370590B true CN112370590B (en) | 2021-09-14 |
Family
ID=74582093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011252415.XA Active CN112370590B (en) | 2020-11-11 | 2020-11-11 | Limb local administration and dialysis device and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112370590B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5326473A (en) * | 1990-09-13 | 1994-07-05 | Lascombes Jean Jacques | Device for extemporaneous and continous preparation of dialysate |
| CN201200674Y (en) * | 2008-06-06 | 2009-03-04 | 段希康 | Infusion device |
| CN104307064A (en) * | 2014-11-06 | 2015-01-28 | 上海市第六人民医院 | Limb local drug delivery and dialysis device and application thereof |
| CN108939183A (en) * | 2018-06-11 | 2018-12-07 | 成都冠禹科技有限公司 | A kind of novel dialytic pipe for hemodialysis apparatus |
| CN210542917U (en) * | 2019-07-08 | 2020-05-19 | 溧阳市中医医院 | Hand and foot surgical nursing device |
| CN111643756A (en) * | 2020-07-13 | 2020-09-11 | 上海市东方医院（同济大学附属东方医院） | Limb local administration and dialysis equipment |
| CN211718229U (en) * | 2019-12-18 | 2020-10-20 | 重庆特斯联智慧科技股份有限公司 | Indoor air quality monitoring devices of multi-functional domestic thing networking |
-
2020
- 2020-11-11 CN CN202011252415.XA patent/CN112370590B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5326473A (en) * | 1990-09-13 | 1994-07-05 | Lascombes Jean Jacques | Device for extemporaneous and continous preparation of dialysate |
| CN201200674Y (en) * | 2008-06-06 | 2009-03-04 | 段希康 | Infusion device |
| CN104307064A (en) * | 2014-11-06 | 2015-01-28 | 上海市第六人民医院 | Limb local drug delivery and dialysis device and application thereof |
| CN108939183A (en) * | 2018-06-11 | 2018-12-07 | 成都冠禹科技有限公司 | A kind of novel dialytic pipe for hemodialysis apparatus |
| CN210542917U (en) * | 2019-07-08 | 2020-05-19 | 溧阳市中医医院 | Hand and foot surgical nursing device |
| CN211718229U (en) * | 2019-12-18 | 2020-10-20 | 重庆特斯联智慧科技股份有限公司 | Indoor air quality monitoring devices of multi-functional domestic thing networking |
| CN111643756A (en) * | 2020-07-13 | 2020-09-11 | 上海市东方医院（同济大学附属东方医院） | Limb local administration and dialysis equipment |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112370590A (en) | 2021-02-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11103281B2 (en) | Apparatus and methods to install, support and/or monitor performance of intraosseous devices | |
| US6692473B2 (en) | Dual lumen adjustable length cannulae for liquid perfusion or lavage | |
| US20080215010A1 (en) | Apparatus and method for using an intraosseous space for moving fluid into and out of the body | |
| CN101626749A (en) | Ultrasound liquid delivery device and methods of using ultrasonic energy to deliver liquids into the body | |
| CA2649098A1 (en) | Apparatus and method for delivery of therapeutic and other types of agents | |
| TAKAHASHI et al. | On the site of action of γ-aminobutyric acid on blood pressure | |
| KR101909869B1 (en) | Injection liquid composition for localized lipolysis and smart mixing system for it | |
| CN112370590B (en) | Limb local administration and dialysis device and application thereof | |
| CN104307064B (en) | Limb local drug delivery and dialysis device and application thereof | |
| US20220273312A1 (en) | Vascular valves and servovalves - and prosthetic disorder response systems | |
| CN110279918B (en) | A kind of mouth-biting nursing device used for relieving ulcer of oral mucosa of patient during chemotherapy | |
| CN207384540U (en) | A kind of blood treatment system | |
| CN204293343U (en) | A kind of intracavitary neoplasm interventional therapy equipment | |
| CN108601517A (en) | For without using conduit by medicament through per urethram pouring into connector, method and the purposes of bladder | |
| CN105596324A (en) | Application of naringenin to preparation of drugs for preventing and/or treating aortic dissection | |
| CN203816006U (en) | Medicament sprayer for use in respiratory medicine | |
| CN209630432U (en) | A kind of hypodermic implantation type drug administration device | |
| CN204275131U (en) | A kind of limbs topical and dialysis apparatus | |
| EA005743B1 (en) | Method for providing a chemical compound into a fluid flowing and apparatus therefor | |
| DE202019005458U1 (en) | System for extracorporeal hyperthermia perfusion (EHP) therapy | |
| CN203043140U (en) | Portable self-control continuous infusion pump | |
| CN215351429U (en) | Intracavity tumor treatment tube | |
| RU203370U1 (en) | DEVICE FOR ADMINISTRATION OF SOLUTIONS BETWEEN NESTING FRAMES IN A BEE FAMILY WITH A LUER LOCK CONNECTOR | |
| CN1057220C (en) | Compound anticancer Chinese medicine | |
| CN104427988A (en) | Liquid medicine having carbon dioxide dissolved therein, and therapeutic method using same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240307 Address after: 222000 No. 38, Huanghe Road, Lianyungang Economic and Technological Development Zone, Lianyungang City, Jiangsu Province Patentee after: JIANGSU HENGRUI MEDICINE Co.,Ltd. Country or region after: China Address before: 226001 Jiangsu city of Nantong province Haier Lane Road, No. 6 Patentee before: Nantong First People's Hospital Country or region before: China |
|
| TR01 | Transfer of patent right |