CN108939183A - A kind of novel dialytic pipe for hemodialysis apparatus - Google Patents

A kind of novel dialytic pipe for hemodialysis apparatus Download PDF

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Publication number
CN108939183A
CN108939183A CN201810593515.5A CN201810593515A CN108939183A CN 108939183 A CN108939183 A CN 108939183A CN 201810593515 A CN201810593515 A CN 201810593515A CN 108939183 A CN108939183 A CN 108939183A
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CN
China
Prior art keywords
blood
dialysis
pipe
patient
needle tubing
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Application number
CN201810593515.5A
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Chinese (zh)
Inventor
赵洪珍
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Chengdu Guanyu Technology Co Ltd
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Chengdu Guanyu Technology Co Ltd
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Priority to CN201810593515.5A priority Critical patent/CN108939183A/en
Publication of CN108939183A publication Critical patent/CN108939183A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14525Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis
    • A61B5/14528Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis invasively
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • A61M1/1623Disposition or location of membranes relative to fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1692Detection of blood traces in dialysate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369Temperature treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics

Abstract

The invention discloses a kind of novel dialytic pipes for hemodialysis apparatus, dialysis needle tubing including dialysis control device and for drawing blood in patient body, described dialysis needle tubing one end is provided with haemodialysis equipment, the haemodialysis equipment is connected separately with for the purified blood Z that dialyses to be re-delivered to blood backflow device in patient body and is used to separate the Zhi Yefenpai mechanism of generation dialysis waste after discharge dialysis, by dialysing, needle tubing extracts blood from the patient, then under the action of haemodialysis equipment, realize dialysis function, and the purified blood Z that will dialyse is fed back in patient body by blood backflow device, at the same time, pass through Zhi Yefenpai mechanism, the waste discharge that dialysis is generated, structure is simple, it is easy to operate, it can be realized efficient to patient blood, the function of immediate dialysis, patient is alleviated to exist The pain in blood dialysis is carried out, ensure that the security reliability of entire dialysis procedure.

Description

A kind of novel dialytic pipe for hemodialysis apparatus
Technical field
The present invention relates to technical field of medical equipment, specially a kind of novel dialytic pipe for hemodialysis apparatus.
Background technique
Haemodialysis is one of acute or chronic renal failure kidneys of patients Replacement Therapy, it is by drawing internal blood It flow in external dialyzer, blood electrolyte solution (dialyzate) similar with concentration containing body passes through inside and outside dialysis membrane Disperse, ultrafiltration and convective principles carry out mass exchange, eliminate intracorporal metabolic waste, maintain electrolyte and acid-base balance;Simultaneously Moisture excessive in vivo is removed, and the whole process of the blood recovery by purification is known as haemodialysis.
Hospital is when carrying out haemodialysis to patient, using special hemodialysis apparatus, the haemodialysis of existing hospital Equipment is commonly present following problem in use:
(1) existing dialysis machine figure is more huge, only configuration in hospital, patient to carry out hemodialysis procedure, Also hospital, which can only be arrived, just can be carried out, and for the patient for needing long term hemodialysis, this just brings very big fiber crops to patient It is tired, need patient periodically to hospital, to increase the seriously ill burden of patient, and when carrying out dialysis operation, it is also necessary to specially The medical staff of door operates hemodialysis apparatus, this also will increase the work load of medical staff;
(2) dialysis membrane in dialysis machine is the indispensable component part for realizing dialysis function, existing dialysis machine It is only the dialysis membrane of hollow structure comprising an inside, when carrying out dialysis operation, the efficiency of dialysis is slow, this will be to disease People brings more pains, moreover, if the patient blood once extracted is excessive, he and dialytic efficiency is very slow, is just easy to make It there is low blood pressure at patient, so, existing dialysis machine can only once extract a small amount of blood, this just makes haemodialysis Efficiency reduce;
(3) after completing dialysis operation, the clean blood of generation can be fed back in patient body existing dialysis machine, and be generated Dialysis waste can be discharged directly with dialyzate, this can cause environmental pollution, so that medical waste increases significantly.
Application No. is a kind of 201711119785.4 entitled patents of invention of hemodialysis tube, the dialysis in the invention is filled The dialysis partial volume set is small, is placed directly in human body artery and carries out haemodialysis, it is not necessary that blood extraction is external again through machine Hemodialysis is carried out, thus on human blood-pressure without influence, safety more more economical than external hemodialysis and wound is small;And it can be retained in blood It is used for multiple times in pipe, is continuously patient and carries out haemodialysis, but problem (2) mentioned above, (3) not can solve.
Summary of the invention
In order to overcome the shortcomings of that prior art, the present invention provide a kind of novel dialytic for hemodialysis apparatus Pipe, structure is simple, easy to operate, can be realized function efficient to patient blood, immediate dialysis, alleviates patient and is carrying out blood Pain in liquid dialysis procedure, ensure that the security reliability of entire dialysis procedure, and can effectively solve that background technique proposes The problem of.
The technical solution adopted by the present invention to solve the technical problems is:
A kind of novel dialytic pipe for hemodialysis apparatus, including dialysis control device and for drawing blood in patient body The dialysis needle tubing of liquid, described dialysis needle tubing one end are provided with haemodialysis equipment, and the haemodialysis equipment is separately connected useful It is generated in purified blood of dialysing to be re-delivered to blood backflow device in patient body and is used to separate after discharge is dialysed The Zhi Yefenpai mechanism of dialysis waste.
Further, the haemodialysis equipment includes bag filter and several fibres in tubular construction filled with dialyzate Dialysis membrane is tieed up, the fiber dialysis membrane is arranged in bag filter, and the dialysis needle tubing lower end is provided with retractable connecting tube A, described The lower end retractable connecting tube A is provided with the first blood transition bag, and the first blood transition bag lower end is provided with several connector A, The connector A is connect with fiber dialysis membrane upper end, and the bag filter left and right ends are respectively arranged with dialyzate entrance and dialysis Waste outlet, the described dialysis one end of Waste outlet far from bag filter are connect with Zhi Yefenpai mechanism, the blood backflow device The lower section of bag filter is set.
Further, the blood backflow device includes the second blood transition bag and blood recovery pipe, second blood The upper end of transition bag is provided with several connector B, the lower end connection of the connector B and fiber dialysis membrane, the blood recovery Pipe one end is connect by retractable connecting tube B with the second blood transition bag lower end.
Further, the Zhi Yefenpai mechanism includes the internal waste pipe for being filled with pure water, described waste pipe one end It is connect by retractable connecting tube C with bag filter outer surface, the inside of waste pipe is provided with infiltration along the discharge direction of dialysis waste Separating layer, and permeability and separation layer one end is connect with dialysis Waste outlet.
Further, the dialysis control device includes introducing blood from the patient to blood for controlling dialysis needle tubing Blood in dialysis apparatus returns control into control valve, for controlling purified blood backflow to the blood in patient body that will be dialysed Valve generates the dialysis row control valve of waste discharge and extracts from the patient for real-time detection dialysis needle tubing for controlling dialysis The monitoring flowmeter of blood volume, the blood returns control valve into control valve, blood and dialysis row's control valve is separately positioned on haemodialysis dress It sets, in blood backflow device, Zhi Yefenpai mechanism, the monitoring flowmeter setting is in dialysis syringe intracavity bottom.
Further, blood warming equipment is provided on the blood recovery pipe, the blood warming equipment includes being arranged Heating water layer is provided between the heating muff of blood recovery tube outer surface, the heating muff and blood recovery pipe, it is described It heats and is provided with fever tablet on the inner wall of water layer.
Further, hemoglobin detection device is provided on the bag filter, the hemoglobin detection device includes Bottom liner card, reaction plate and sample-adding are managed, and are provided on the reaction plate recessed for the reaction of placing response reagent and lysis reagent Slot, described sample-adding pipe one end are arranged in bag filter, and the other end passes through the outside that bag filter extends to bag filter, and recessed with reacting The one end of reaction plate far from sample-adding pipe is arranged in slot connection, the bottom liner card.
Further, it is provided with the blood dispersion plate of domes in the connector A, is arranged on the blood dispersion plate There are several dispersion holes.
Further, anti-coagulants adding mouth is provided on the dialysis needle tubing.
Further, the permeability and separation layer is helicoidal structure.
Compared with prior art, the beneficial effects of the present invention are:
(1) present invention is by the setting of haemodialysis equipment, it can be achieved that the function that patient blood is efficiently dialysed, so that doctor Business personnel can once extract the more blood of patient, and be within a short period of time when carrying out hemodialysis procedure to patient Achievable haemodialysis, and under the action of blood backflow device, blood of the dialysis after clean is back in patient body again, The more blood of operation extraction of once dialysing is effectively prevented, patient's low blood pressure is be easy to cause, meanwhile, substantially increase haemodialysis Efficiency, alleviate the pain of patient;
(2) present invention passes through the setting of Zhi Yefenpai mechanism, can carry out classification discharge to the waste generated through haemodialysis, Avoid pollution of the dialysis waste of direct emission to environment;
(3) present invention, can be during haemodialysis entire to patient, by manual by setting dialysis control device Control is easy to operate to realize dialysis control function, meanwhile, but also the novel dialytic pipe for being used for hemodialysis apparatus is whole Body structure is simpler, after installing the dialysis tubing, can complete entire hemodialysis procedure process by patient oneself;
(4) present invention is by the setting of blood warming equipment, it can be achieved that heating up to the blood heat being fed back in patient body Function, the blood for avoiding temperature too low brings serious sense of discomfort to patient, the slight illness of patient aggravated, by using heating water bath Mode, realize blood temperature rise effect, can avoid blood temperature rise it is too high, cause patient low blood pressure phenomenon occur;
(5) present invention, can be in blood dialysis, by detecting dialyzate by the setting of hemoglobin detection device In whether contain blood, easy to operate to judge whether fiber dialysis membrane ruptures, required production cost is also relatively low, It avoids in blood dialysis, since dialysis membrane rupture is found not in time, dialyzate is caused to be back to together with blood In patient body, it ensure that the security reliability during the novel dialytic pipe work for hemodialysis apparatus.
Detailed description of the invention
Fig. 1 is overall structure diagram of the invention;
Fig. 2 is hemoglobin detection device right side structural representation of the invention;
Fig. 3 is blood dispersion plate overlooking structure diagram of the invention;
Fig. 4 is the enlarged structure schematic diagram of A in Fig. 1 of the invention;
Fig. 5 is the enlarged structure schematic diagram of B in Fig. 1 of the invention;
Fig. 6 is the enlarged structure schematic diagram of C in Fig. 1 of the invention;
Fig. 7 is hemoglobin detection device overlooking structure diagram of the invention.
Figure label:
1- dialysis control device;2- dialysis needle tubing;3- haemodialysis equipment;4- blood backflow device;5- matter liquid divides row's machine Structure;6- blood warming equipment;7- hemoglobin detection device;8- blood dispersion plate;9- dispersion hole;10- anti-coagulants adding mouth;
101- blood into control valve;102- blood returns control valve;103- dialysis row's control valve;104- monitors flowmeter;
301- bag filter;302- fiber dialysis membrane;303- retractable connecting tube A;304- the first blood transition bag;305- connection Mouth A;306- dialyzate entrance;307- dialysis Waste outlet;
401- the second blood transition bag;402- blood recovery pipe;403- connector B;404- retractable connecting tube B;
501- waste pipe;502- retractable connecting tube C;503- permeability and separation layer;
601- heating muff;602- heats water layer;603- fever tablet;
701- bottom liner card;702- reaction plate;703- sample-adding pipe;704- reacts groove.
Blood before X- dialysis;Y- dialyzate;The purified blood of Z- dialysis
Specific embodiment
As shown in Figures 1 to 7, the present invention provides a kind of novel dialytic pipes for hemodialysis apparatus, including dialysis Dialysis needle tubing 2 is injected disease when carrying out dialysis operation by control device 1 and dialysis needle tubing 2 for drawing blood in patient body In human artery, described 2 one end of dialysis needle tubing is provided with haemodialysis equipment 3, and the haemodialysis equipment 3, which is connected separately with, to be used for Purified blood of dialysing is re-delivered to blood backflow device 4 in patient body and is generated thoroughly after being used to separate discharge dialysis Analyse the Zhi Yefenpai mechanism 5 of waste.
The haemodialysis equipment 3 include filled with dialyzate bag filter 301 and several fibers in tubular construction it is saturating Film 302 is analysed, the fiber dialysis membrane 302 is arranged in bag filter 301, and the setting of multiple fiber dialysis membranes 302 is increased to saturating The blood of analysis and the contact area of dialyzate Y improve dialytic efficiency, avoid due to saturating to realize preferably dialysis-effect The analysis time is long, increases the pain of patient, 2 lower end of dialysis needle tubing is provided with retractable connecting tube A303, retractable connecting tube The setting of A303 avoids outer bound pair from dialysing so that having certain telescopic adjustment ability between dialysis needle tubing 2 and bag filter 301 Intentional or unintentional shaking, the collision of bag 301 are easy to cause dialysis needle tubing 2 to extract from the patient, cause secondary wound to patient Evil.
The lower end the retractable connecting tube A303 is provided with the first blood transition bag 304, passes through the first blood transition bag 304 Setting plays the role of transition storage, and realize to dialysis to the blood X before the patient's dialysis extracted through dialysis needle tubing 2 The function that the patient blood that needle tubing 2 extracts separately is dialysed, so that the dialysis tubing can be extracted once when carrying out hemodialysis procedure Then more blood carries out the blood of extraction to separate dialysis operation simultaneously, so as to disease by several fiber dialysis membranes 302 The dialysis fast speed of human blood, to substantially increase the efficiency of patient blood dialysis, realization will dialyse purified blood Z The effect of being fed back in patient body again in a short time, conventional hemodialysis is efficiently solved, once extracts more disease When human blood, the problem of causing patient's low blood pressure, faint.
First blood transition bag, 304 lower end is provided with several connector A305, and the connector A305 and fiber are saturating The connection of 302 upper end of film is analysed, 301 left and right ends of bag filter are respectively arranged with dialyzate entrance 306 and dialysis Waste outlet 307, by the setting of dialyzate entrance 306, facilitates and be continuously added new dialyzate into bag filter 301 and (pass through bag filter The operation of new dialyzate is added into bag filter 301 for entrance 306, is that the dialyzate in each bag filter 301 completes a blood Liquid dialysis operation, and under the action of Zhi Yefenpai mechanism 5, by the dialyzate Y of blood of having dialysed in bag filter 301 After being completely exhausted out, then new dialyzate Y is rejoined into bag filter 301, thus be not in new dialyzate with it is old saturating The problem of analysing liquid mixing, reducing dialytic efficiency), it ensure that dialyzate can complete the requirement of dialysis function in bag filter 301, keep away Exempt from repeatedly dialyse so that dialyzate fail, influence haemodialysis effect, be additionally provided with control valve on dialyzate entrance 306, lead to The opening and closing operation of control valve is crossed, for realizing adding dialyzate into bag filter 301 and stopping addition dialyzate Function, the described dialysis one end of Waste outlet 307 far from bag filter 301 connect with Zhi Yefenpai mechanism 5, the blood backflow The lower section of bag filter 301 is arranged in device 4.
By dialysing, needle tubing 2 extracts blood out of patient artery, and introduces in bag filter 301, in fiber dialysis membrane 302 Under effect, the dialysis function to patient blood is realized, moreover, in dialysis procedure, it can also be by rocking bag filter manually 301, increase the contact area of dialyzate Y and blood, time of contact in bag filter 301, improve solute penetration efficiency, realizes good Function of ground dialysing is reduced because dialysis time is longer, bitterly to patient's bring so that greatly shortening the time required to blood dialysis Hardship, after the completion of dialysis, the metabolic waste that contains in patient blood is discharged from dialysis Waste outlet 307 together with dialyzate Y, and By dialysing, purified blood Z can be back to again in patient body under the action of blood backflow device 4, avoid patient body Interior loss of blood is excessive, causes low blood pressure, in entire blood dialysis, operates relatively simple, can assign the dialysis tubing solid It is scheduled on patient, patient can carry out hemodialysis procedure at any time, eliminate patient and need that hospital is periodically gone to carry out haemodialysis Trouble.
It is explained further, which worked based on penetration theory, before patient dialyses Blood X and dialyzate Y is introduced in bag filter 301 simultaneously, due to containing a large amount of metabolic waste in patient blood, can make patient The concentration of blood is higher, and the environment in dialyzate Y is similar with blood of human body environment, and only the concentration of dialyzate Y is lower, institute With, small-molecule substance in the patient blood of high concentration, if glucose and metabolic waste urea can pass through fiber dialysis membrane 302, Into in dialyzate, finally it is discharged together with dialyzate from dialysis Waste outlet 307.
It remarks additionally, K+, Na+, Ca2+, Mg2+, Cl-, HCO3- and acetic acid is contained in dialyzate, in order to guarantee disease Useful component in human blood is not lost, and in dialyzate Y, in addition to urea, ingredient and concentration and human plasma are completely the same.
The blood backflow device 4 includes the second blood transition bag 401 and blood recovery pipe 402, is carrying out haemodialysis It when operation, needs to inject 402 one end of blood recovery pipe in venous patient, the upper end of the second blood transition bag 401 is arranged There are several connector B403, the connector B403 to connect with the lower end of fiber dialysis membrane 302, by the way that the second blood transition is arranged Bag 401, to dialysing, purified blood Z storage plays transitional function, so that being dialysed purified blood Z slowly, uniformly Ground by blood recovery pipe 402 be back to avoid in patient body more blood be all back in a flash in patient body, hold Patient is easily caused spinning sensation occur.
Described 402 one end of blood recovery pipe, which is connect by retractable connecting tube B404 with 401 lower end of the second blood transition bag, (stretches The structure and functional characteristics of contracting connecting tube B404 and retractable connecting tube A303 be it is the same, for playing certain be telescopically connected to Effect), the setting of retractable connecting tube B404, so that having centainly between blood recovery pipe 402 and the second blood transition bag 401 Flexible tunability effectively prevents the extraneous intentionally or accidentally shaking to the second blood transition bag 401, causes blood recovery pipe 402 fall off from the patient, ensure that the dialysis procedure safely and reliably carries out.
The Zhi Yefenpai mechanism 5 includes the internal waste pipe 501 for being filled with pure water, and the concentration of pure water is very low, can Realize the function of preferable geology liquid separation, described 501 one end of waste pipe by retractable connecting tube C502 (retractable connecting tube C502 with Retractable connecting tube A404, the structure of retractable connecting tube B303 and functional characteristics are consistent, bellows can be used in the present invention, by hundred Encyclopaedia is spent it is found that bellows refers to the tubular elastomeric sensing element connected into foldable wrinkle piece along folding retractable direction, is had Have certain retractility) it is connect with 301 outer surface of bag filter, the inside of waste pipe 501 is arranged along the discharge direction of dialysis waste There is permeability and separation layer 503, and described 503 one end of permeability and separation layer is connect with dialysis Waste outlet 307, by fiber dialysis membrane After 302 pairs of blood carry out dialysis operation, the metabolic waste in blood is being arranged as dialyzate is from the dialysis discharge of Waste outlet 307 During out, under the action of permeability and separation layer 503, the small-molecule substances such as the metabolic waste contained in dialyzate can be precipitated to Between waste pipe 501 and permeability and separation layer 503, so that the function that solute and solution separately discharge is realized, as shown in figure 5, top What arrow indicated is the discharge direction of solute in waste liquid;What the arrow of lower section indicated is the discharge direction of solution in waste liquid.
The working principle of the permeability and separation layer 503 is similar with the working principle of haemodialysis equipment 3.
The dialysis control device 1 includes introducing blood from the patient to haemodialysis dress for controlling dialysis needle tubing 2 The purified blood Z that the dialyses blood being back in patient body is returned control valve into control valve 101, for controlling by the blood set in 3 102, for controlling the dialysis row control valve 103 of dialysis generation waste discharge and dialysing needle tubing 2 from the patient for real-time detection The monitoring flowmeter 104 of the blood volume of extraction, the blood returns control valve 102 into control valve 101, blood and dialysis row's control valve 103 divides The retractable connecting tube A303 of haemodialysis equipment 3, the retractable connecting tube B404 of blood backflow device 4, matter liquid point row are not set On the retractable connecting tube C502 of mechanism 5, blood used in the present invention returns control valve 102 and dialysis row's control into control valve 101, blood Valve 103 is common manually-operated gate, according to Baidupedia it is found that manually-operated gate is control unit in pipeline fluid conveying system Part, it is that have water conservancy diversion, cut-off, adjusting, throttling, non-return, shunting or overflow for changing access section and flow direction of medium The functions such as release, the monitoring flowmeter 104 setting in dialysis 2 intracavity bottom of needle tubing, can real-time measurement dialyse needle tubing 2 from disease The blood volume extracted in human body, accurately control dialysis blood volume, convenient for medical worker quickly to occurring in patient's dialysis procedure Undesirable condition makes accurate judgement, blood into control valve 101, blood return control valve 102 and dialysis row's control valve 103 can by patient or Person is that medical worker manually controls, and operation is very easy, plays effective control action to the entire dialysis procedure of patient, ensure that The reliability of operation of dialysing and the profitability to Case treatment pass through monitoring flowmeter 104 when carrying out hemodialysis procedure The blood volume that real-time measurement extracts, and the primary extraction blood figureofmerit provided according to medical worker carry out blood into control valve 101 Switch control operations, the monitoring flowmeter 104 in the present invention is common technique means, by hundred using fluid flowmeter Degree encyclopaedia is it is found that fluid flowmeter is to be manufactured according to karman vortex principle for measuring liquid in sealing pipeline, gas, steam flow Precision instrument.
As preferred embodiment, blood warming equipment 6 is provided on the blood recovery pipe 402, the blood adds Warm device 6 includes the heating muff 601 for being set in 402 outer surface of blood recovery pipe, the heating muff 601 and blood recovery pipe It is provided with heating water layer 602 between 402, is provided with fever tablet 603 on the inner wall of the heating water layer 602, fever tablet 603 is one The heating element that kind sheet can generate heat carries out heat temperature raising to heating water layer 602, temperature increases by the setting of fever tablet 603 Heating water layer 602 so that the function of heating water bath heating is realized to the blood in blood recovery pipe 402, heating water layer 602 Setting, on the one hand, play the role of uniformly heated, heat is avoided to be gathered in 603 somewhere of fever tablet, and cause other positions Temperature is still lower, and then keeps blood heating uneven, brings uncomfortable feeling to patient;On the other hand, heating water layer 602 plays The effect of transition heat temperature raising is heated by 603 pairs of heating water layers 602 of fever tablet, then by heating water layer 602 for heat It is transmitted in the blood in blood recovery pipe 402, the directly contact blood recovery pipe 402 of fever tablet 603 is avoided, so that blood returns Blood local heating in defeated pipe 402 is too fast, and causes local blood temperature too high, gives patient's bring sense of discomfort.
Since by the purified blood Z of dialysing, temperature is usually less than blood heat, if direct feedback is to patient In vivo, patient can feel uncomfortable, by the setting of blood warming equipment 6, can feed back patient to the purified blood Z that dialyses During intracorporal, the heating function to blood is realized, guarantee the temperature for flowing into blood in patient body and blood in patient body Temperature is close, avoids blood temperature lower, causes sense of discomfort to patient.
It further illustrates, if the blood temperature being fed back in patient body is excessively high, equally can bring discomfort to patient Sense be easy to cause patient low blood pressure phenomenon occur, in the present invention, by using the mode of heating water bath, realizes to blood recovery Blood in pipe 402 carries out heat temperature raising effect, blood can be made to be heated evenly, and since heating water bath effect is preferable, water-bath adds The uniform feature of heat, so not will cause, blood temperature is raised too many, too fast, and this makes it possible to guarantee to be fed back in patient body Blood temperature and patient's own temperature it is close, pain will not be brought to patient.
As preferred embodiment, hemoglobin detection device 7, the blood red egg are provided on the bag filter 301 White detection device 7 includes bottom liner card 701, reaction plate 702 and sample-adding pipe 703, is provided on the reaction plate 702 for placing The reaction groove 704 of reaction reagent and lysis reagent, described 703 one end of sample-adding pipe are arranged in bag filter 301, and the other end passes through Bag filter 301 extends to the outside of bag filter 301, and connect with reaction groove 704, and the setting of bottom liner card 701 is being reacted The one end of plate 702 far from sample-adding pipe 703.
Since fiber dialysis membrane 302 is than relatively thin, in dialysis procedure, due to the percussion and extraneous intentional nothing of blood Extruding of the meaning ground to it, it is easy to the rupture for causing fiber dialysis membrane 302, the fiber dialysis membrane 302 after rupture, so that dialysis blood Liquid is passed out into dialyzate, whether can contain hemoglobin in real-time detection dialyzate by hemoglobin detection device 7, It can effectively avoid dialyzate by the detection to hemoglobin in dialyzate to determine whether fiber dialysis membrane 302 ruptures It is back to the internal of patient also along blood recovery pipe 402, ensure that the novel dialytic pipe work for hemodialysis apparatus Security reliability in the process.
The working principle of the hemoglobin detection device 7 is as follows:
By being loaded pipe 703, the dialyzate of bag filter 301 is added in the reaction groove 704 on reaction plate 702, is made It reacts with reaction reagent, the lysis reagent reacted in groove 704, if fiber dialysis membrane 302 ruptures, in dialyzate Containing blood, the red blood cell in blood is cracked through lysis reagent, releases hemoglobin, and reacting again with reaction reagent can give birth to later At specific color, the setting of bottom liner card 701 is for reaction reagent to be reacted the color generated and bottom liner card 701 certainly What the color of body was made comparisons, it is equivalent to color quantification, can determine whether fiber dialysis membrane 302 breaks according to color comparison result It splits.
The operation detection process speed of entire hemoglobin detection device 7 is fast, high-efficient, easy to operate, moreover, pass through by The one end of reaction plate 702 far from sample-adding pipe 703 is arranged in bottom liner card 701, and the detection liquid that can effectively avoid in sample-adding pipe 703 splashes Onto bottom liner card 701, adverse effect is brought to testing result.
The blood dispersion plate 8 of domes is provided in the connector A305, if being provided on the blood dispersion plate 8 Dry dispersion hole 9, the setting of blood dispersion plate 8 can carry out decentralized processing to the blood that needle tubing 2 extracts from the patient of being dialysed, It avoids too sticky blood from blocking fiber dialysis membrane 302, is not easy to subsequent dialysis operation, disperses by the blood of domes After plate 8, sticky blood is separated, is then flowed into fiber dialysis membrane 302 by dispersion hole 9.
It is provided with anti-coagulants adding mouth 10 on the dialysis needle tubing 2, by the setting of anticoagulation adding mouth 10, can dialysed When needle tubing 2 extracts blood from the patient, anti-coagulants is added into blood, with remove or inhibit certain blood coagulations in blood because Son prevents blood clotting, avoids the blood blocking connector A305 or fiber dialysis membrane 302 of solidification, influences haemodialysis effect, More pains are brought to patient.
The permeability and separation layer 503 is helicoidal structure, and the setting of the permeability and separation layer 503 of helicoidal structure may make The time of contact of dialysis waste and permeability and separation layer 503 is longer, so that preferably osmotic effect is realized, so that matter liquid separating effect It is more significant.
The application method for being used for the novel dialytic pipe of hemodialysis apparatus includes the following steps:
S100, dialysis needle tubing one end, blood recovery pipe one end are separately inserted patient artery and intravenous;
S200, it is dialysed by the patient blood that haemodialysis equipment extracts dialysis needle tubing;
S300, by haemodialysis equipment in step S200 for a period of time dialysis operation after, by clean blood of dialysing It is fed back in patient body by blood backflow device, at the same time, the waste that dialysis is generated is discharged by Zhi Yefenpai mechanism.
It is explained further, why dialysis needle tubing 2 is injected in patient artery and carry out blood drawing dialysis, by blood recovery Pipe 402 injects in venous patient, realizes blood backflow, is because blood pressure is higher in artery, it is external to be conducive to blood outflow, and quiet Blood pressure is lower in arteries and veins, is conducive in blood stream ex vivo, while to can effectively prevent blood backflow saturating to blood for the venous valve in vein In analysis apparatus 3.
Supplementary explanation, venous valve are two semilune thin slices, and opposite to each other, root is connected with tunica intima of vein, trip From edge towards blood flow direction, play the role of preventing backflow of blood, whole body removes the quiet of most of organs of internal organ, brain and incidence Arteries and veins without vein valve outside, the vein of the vein caliber 2mm or more of the vein in remaining each portion has venous valve, the venous valve of limb vein More, especially lower limb are more flourishing, when carrying out haemodialysis, can be selected according to demand.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.

Claims (10)

1. a kind of novel dialytic pipe for hemodialysis apparatus, it is characterised in that: including dialysis control device (1) and for drawing The dialysis needle tubing (2) of blood, described dialysis needle tubing (2) one end are provided with haemodialysis equipment (3), the blood in patient body out Dialysis apparatus (3), which is connected separately with, is re-delivered to blood backflow device in patient body for the purified blood that will dialyse (4) and for separating the Zhi Yefenpai mechanism (5) for generating dialysis waste after discharge is dialysed.
2. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 1, it is characterised in that: the blood Dialysis apparatus (3) includes bag filter (301) and several fiber dialysis membranes (302) in tubular construction filled with dialyzate, institute Fiber dialysis membrane (302) setting is stated in bag filter (301), dialysis needle tubing (2) lower end is provided with retractable connecting tube A (303), retractable connecting tube A (303) lower end is provided with the first blood transition bag (304), the first blood transition bag (304) lower end is provided with several connector A (305), and the connector A (305) connect with fiber dialysis membrane (302) upper end, institute It states bag filter (301) left and right ends and is respectively arranged with dialyzate entrance (306) and dialysis Waste outlet (307), the dialysis is useless Object outlet (307) is connect far from the one end of bag filter (301) with Zhi Yefenpai mechanism (5), blood backflow device (4) setting In the lower section of bag filter (301).
3. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 2, it is characterised in that: the blood Reflux unit (4) includes the second blood transition bag (401) and blood recovery pipe (402), the second blood transition bag (401) Upper end is provided with several connector B (403), and the connector B (403) connect with the lower end of fiber dialysis membrane (302), the blood Liquid feeds back pipe (402) one end and is connect by retractable connecting tube B (404) with second blood transition bag (401) lower end.
4. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 2, it is characterised in that: the matter liquid Fen Pai mechanism (5) includes the internal waste pipe (501) for being filled with pure water, and described waste pipe (501) one end is by being telescopically connected to Pipe C (502) is connect with bag filter (301) outer surface, and the inside of waste pipe (501) is provided with infiltration along the discharge direction of dialysis waste Saturating separating layer (503), and described permeability and separation layer (503) one end is connect with dialysis Waste outlet (307).
5. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 1, it is characterised in that: the dialysis Control device (1) includes introducing blood from the patient to the blood in haemodialysis equipment (3) for controlling dialysis needle tubing (2) Control valve (102) are gone back into control valve (101), for controlling purified blood backflow to the blood in patient body that will be dialysed, are used for Control dialysis generates dialysis row's control valve (103) of waste discharge and extracts from the patient for real-time detection dialysis needle tubing (2) Blood volume monitoring flowmeter (104), the blood into control valve (101), blood return control valve (102) and dialysis row control valve (103) haemodialysis equipment (3), blood backflow device (4) are separately positioned on, in Zhi Yefenpai mechanism (5), the monitoring flow (104) setting is counted in dialysis needle tubing (2) intracavity bottom.
6. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 3, it is characterised in that: the blood It feeds back and is provided with blood warming equipment (6) on pipe (402), the blood warming equipment (6) includes being set in blood recovery pipe (402) heating muff (601) of outer surface is provided with heating water between the heating muff (601) and blood recovery pipe (402) Layer (602), it is described heating water layer (602) inner wall on be provided with fever tablet (603).
7. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 2, it is characterised in that: the dialysis Bag (301) on be provided with hemoglobin detection device (7), the hemoglobin detection device (7) include bottom liner card (701), Reaction plate (702) and sample-adding pipe (703) are provided on the reaction plate (702) for placing response reagent and lysis reagent It reacts groove (704), in bag filter (301), the other end passes through bag filter (301) and prolongs for the sample-adding pipe (703) one end setting The outside of bag filter (301) is extended to, and is connect with reaction groove (704), the bottom liner card (701) is arranged in reaction plate (702) one end far from sample-adding pipe (703).
8. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 2, it is characterised in that: the connection It is provided with the blood dispersion plate (8) of domes in mouth A (305), is provided with several dispersion holes on the blood dispersion plate (8) (9)。
9. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 1, it is characterised in that: the dialysis Anti-coagulants adding mouth (10) are provided on needle tubing (2).
10. a kind of novel dialytic pipe for hemodialysis apparatus according to claim 4, it is characterised in that: the infiltration Saturating separating layer (503) is helicoidal structure.
CN201810593515.5A 2018-06-11 2018-06-11 A kind of novel dialytic pipe for hemodialysis apparatus Withdrawn CN108939183A (en)

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CN110354326A (en) * 2019-07-30 2019-10-22 河南科技大学第一附属医院 A kind of haemodialysis monitoring care device of adjustable filtration yield
CN112370590A (en) * 2020-11-11 2021-02-19 南通市第一人民医院 Limb local administration and dialysis device and application thereof
CN113082332A (en) * 2021-04-08 2021-07-09 上海医药血液技术产业发展有限公司 Hemodialysis pipe part and hemodialysis device

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CN101784292A (en) * 2007-08-23 2010-07-21 弗雷泽纽斯医疗保健控股有限公司 Artificial kidney dialysis system
US20170112991A1 (en) * 2013-01-09 2017-04-27 Medtronic, Inc. Recirculating dialysate fluid circuit for blood measurement
CN107073190A (en) * 2014-09-12 2017-08-18 简便透析有限公司 Portable blood dialysis component with ammoniacal sensor
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CN110354326A (en) * 2019-07-30 2019-10-22 河南科技大学第一附属医院 A kind of haemodialysis monitoring care device of adjustable filtration yield
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CN112370590B (en) * 2020-11-11 2021-09-14 南通市第一人民医院 Limb local administration and dialysis device and application thereof
CN113082332A (en) * 2021-04-08 2021-07-09 上海医药血液技术产业发展有限公司 Hemodialysis pipe part and hemodialysis device

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