CN112370517A - Pure traditional Chinese medicine transdermal liniment for treating breast cancer and preparation method thereof - Google Patents

Abstract

The invention discloses a pure traditional Chinese medicine transdermal liniment for treating breast cancer, which comprises the following raw materials in parts by weight: 15-20 parts of alkanna tinctoria root, 15-20 parts of honeysuckle, 15-20 parts of Chinese violet, 10-12 parts of turmeric root-tuber, 10-12 parts of pangolin scales, 15-18 parts of angelica dahurica, 6-9 parts of scorpion, 9-12 parts of saffron crocus, 9-12 parts of ground beeltle and 3-6 parts of snow lotus herb; the invention also discloses a preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer, which comprises the following steps: (1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder; (2) the mashed mixed powder is put into 50 to 100 weight parts of alcohol to be soaked for 20 to 25 days for use. The invention has the advantages of safe raw materials, reasonable proportioning, no side effect, obvious treatment effect, lower cost, simple preparation method and better drug effect of the raw materials.

Description

Pure traditional Chinese medicine transdermal liniment for treating breast cancer and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a pure traditional Chinese medicine transdermal liniment for treating breast cancer and a preparation method thereof.

Background

According to related data, the incidence of breast cancer is the first of female malignant tumors in the world, and the serious patients face the risk of cutting out the breast and directly affect the physical health of the female; at present, most of medicines for treating breast cancer are oral western medicines or traditional Chinese medicines, the western medicines have great side effects and are easy to generate drug resistance, the existing traditional Chinese medicines for treating breast cancer are all oral medicines and need to be decocted, and the raw materials and the proportion are not good, so that the treatment effect is not obvious.

Disclosure of Invention

The invention aims to provide a pure traditional Chinese medicine transdermal liniment for treating breast cancer, which has the effects of thermally decomposing and detoxifying, diminishing inflammation and detumescence, promoting qi circulation and relieving depression, stimulating the menstrual flow and promoting lactation, expelling pus and promoting granulation, dredging collaterals and relieving pain, and treating breast distending pain, so that the effect of treating breast cancer is achieved.

In order to achieve the first purpose, the invention adopts the following technical scheme:

a pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following raw materials in parts by weight: 15-20 parts of alkanna tinctoria root, 15-20 parts of honeysuckle, 15-20 parts of Chinese violet, 10-12 parts of turmeric root-tuber, 10-12 parts of pangolin scales, 15-18 parts of angelica dahurica, 6-9 parts of scorpion, 9-12 parts of saffron crocus, 9-12 parts of ground beeltle and 3-6 parts of snow lotus herb.

Preferably, the feed comprises the following raw materials in parts by weight: 15 parts of alkanna tinctoria root, 15 parts of honeysuckle, 15 parts of Chinese violet, 10 parts of turmeric root-tuber, 10 parts of pangolin scales, 15 parts of dahurian angelica root, 6 parts of scorpion, 9 parts of saffron, 9 parts of ground beetle and 3 parts of snow lotus herb.

Preferably, the feed comprises the following raw materials in parts by weight: 17 parts of alkanna tinctoria root, 18 parts of honeysuckle, 17 parts of Chinese violet, 11 parts of turmeric root-tuber, 11 parts of pangolin scales, 16 parts of dahurian angelica root, 7 parts of scorpion, 10 parts of saffron, 10 parts of ground beetle and 5 parts of snow lotus herb.

Preferably, the feed comprises the following raw materials in parts by weight: 20 parts of alkanna tinctoria root, 20 parts of honeysuckle, 20 parts of Chinese violet, 12 parts of turmeric root-tuber, 12 parts of pangolin scales, 18 parts of dahurian angelica root, 9 parts of scorpion, 12 parts of saffron, 12 parts of ground beeltle and 6 parts of snow lotus herb.

The invention aims to provide a preparation method of a pure traditional Chinese medicine transdermal liniment for treating breast cancer, which has simple steps, and ensures that the raw materials are fully fused to exert the drug effect.

In order to achieve the second object, the invention adopts the following technical scheme:

a method for preparing a pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following steps:

(1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder;

(2) the mashed mixed powder is put into 50 to 100 weight parts of alcohol to be soaked for 20 to 25 days for use.

Preferably, the alcohol concentration in step (2) is 75%.

The raw materials in the invention have the following effects:

root of purple grass: has effects of cooling blood, promoting blood circulation, removing toxic substance and promoting eruption.

Honeysuckle flower: has effects of clearing away heat and toxic materials, relieving inflammation, and relieving swelling.

Herba Violae: has the functions of clearing away heat and toxic material, cooling blood, eliminating swelling, clearing away heat and promoting diuresis.

Turmeric root-tuber: has effects in promoting blood circulation, relieving pain, activating qi-flowing, resolving stagnation, clearing away heart-fire, cooling blood, promoting bile flow, and eliminating jaundice; can be used for treating pricking pain in chest and hypochondrium, amenorrhea, dysmenorrhea, and breast distending pain.

Nail bead: has effects in relieving swelling, ulcer, carbuncle, expelling pathogenic wind, activating collateral flow, dredging meridian, and promoting lactation; it is indicated for abscess, deep-rooted carbuncle, sore and swelling, arthralgia due to wind-cold-dampness, amenorrhea, galactostasis and hematochezia.

Radix angelicae: has effects in eliminating diseases, removing dampness, promoting pus discharge, promoting granulation, promoting blood circulation, and relieving pain.

Scorpion: has effects of calming endogenous wind, relieving spasm, dredging collaterals, relieving pain, removing toxic substance, and resolving hard mass.

Saffron: has effects in promoting blood circulation, dispelling blood stasis, and resolving stagnation; can be used for treating melancholia, chest distress, amenorrhea, puerperal abdominal pain due to blood stasis, and traumatic injury with swelling and pain.

Ground beetle: has effects in removing blood stasis, promoting reunion of fractured tendons and bones; can be used for treating amenorrhea due to blood stasis and puerperal abdominal pain due to blood stasis.

Snow lotus herb, Tianshan: has the effects of warming kidney, supporting yang, dispelling pathogenic wind, eliminating dampness, dredging channels and promoting blood circulation.

The invention has the beneficial effects that: the pure traditional Chinese medicine transdermal liniment for treating breast cancer adopts a liniment mode, and is convenient to use; the Chinese medicinal liniment has the effects of thermally decomposing and detoxifying, diminishing inflammation and detumescence, promoting qi circulation and resolving depression, stimulating the menstrual flow and promoting lactation, expelling pus and promoting granulation, dredging collaterals and relieving pain and treating breast distending pain, so that the effect of treating breast cancer is achieved, and the Chinese medicinal raw materials are adopted, so that the raw materials are safe, the proportion is reasonable, side effects and drug resistance cannot be generated, the treatment effect is obvious, and the treatment cost is lower; the preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer has simple steps, and the raw materials are fully fused by using alcohol, so that the drug effect is better exerted.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example one

A pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following raw materials in parts by weight: 15 parts of alkanna tinctoria root, 15 parts of honeysuckle, 15 parts of Chinese violet, 10 parts of turmeric root-tuber, 10 parts of pangolin scales, 15 parts of dahurian angelica root, 6 parts of scorpion, 9 parts of saffron, 9 parts of ground beetle and 3 parts of snow lotus herb.

The preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following steps:

(1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder;

(2) the mashed mixed powder is put into 50 parts by weight of 75% alcohol to be soaked for 20 days.

Example two

A pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following raw materials in parts by weight: 17 parts of alkanna tinctoria root, 18 parts of honeysuckle, 17 parts of Chinese violet, 11 parts of turmeric root-tuber, 11 parts of pangolin scales, 16 parts of dahurian angelica root, 7 parts of scorpion, 10 parts of saffron, 10 parts of ground beetle and 5 parts of snow lotus herb.

The preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following steps:

(1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder;

(2) and (3) putting the mashed mixed powder into 75 parts by weight of 75% alcohol, and soaking for 22 days.

EXAMPLE III

A pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following raw materials in parts by weight: 20 parts of alkanna tinctoria root, 20 parts of honeysuckle, 20 parts of Chinese violet, 12 parts of turmeric root-tuber, 12 parts of pangolin scales, 18 parts of dahurian angelica root, 9 parts of scorpion, 12 parts of saffron, 12 parts of ground beeltle and 6 parts of snow lotus herb.

The preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer comprises the following steps:

(1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder;

(2) the mashed mixed powder is put into 100 parts by weight of alcohol with the concentration of 75 percent for soaking for 25 days.

The use method of the above embodiment of the invention is as follows: when in use, the pure traditional Chinese medicine transdermal liniment is rubbed on skin acupuncture points for 3 times a day, and a treatment course is 40 days.

Clinical trial

1. Basic data

180 patients with confirmed breast cancer are selected, the age distribution is 35-65 years, the disease course is 4 months-3 years, and symptoms of the patients include breast distending pain, stabbing pain, internal lumps, nipple discharge, breast skin abnormality, areola abnormality and lymph node swelling.

2. Test method

Setting six groups of test cases, namely a first example, a second example, a third example, a first comparison example, a second comparison example and a third comparison example, wherein each group of test cases is randomly distributed with 30 persons, and each group of test cases is respectively treated with corresponding medicaments of the group for 40 days;

in the comparative example, the raw materials in the first example are replaced by: 15 parts of alkanna tinctoria root, 15 parts of honeysuckle, 15 parts of Chinese violet, 10 parts of pangolin scales, 15 parts of angelica dahurica, 6 parts of scorpion, 9 parts of saffron crocus, 9 parts of ground beetle and 3 parts of snow lotus herb;

the second comparative example replaces the raw materials in the second example with: 17 parts of alkanna tinctoria root, 18 parts of honeysuckle, 17 parts of Chinese violet, 11 parts of turmeric root-tuber, 7 parts of scorpion, 10 parts of saffron, 10 parts of ground beetle and 5 parts of snow lotus herb.

In a third comparative example, the raw materials in the third example are replaced by: 20 parts of alkanna tinctoria root, 20 parts of honeysuckle, 12 parts of pangolin scales, 18 parts of angelica dahurica, 9 parts of scorpion, 12 parts of ground beetle and 6 parts of snow lotus herb.

3. Judgment of therapeutic effect

The therapeutic effect judgment standard is divided into four grades of cure, obvious effect, effective and ineffective.

And (3) curing: tumor was eliminated without clinical symptoms.

The effect is shown: the tumor is mostly eliminated, and the clinical symptoms are relieved.

The method has the following advantages: the tumor is partially eliminated, and the clinical symptoms are relieved.

And (4) invalidation: there was no change in tumor and no change in clinical symptom expression.

4. Test results

The liniment of the present invention has significant effect on treating breast cancer.

Typical case 1:

the pure traditional Chinese medicine transdermal liniment prepared by the invention is applied for 3 times every day, after continuously using for one treatment course, the pain is relieved, the lumps are reduced, after continuously using for two treatment courses, the pain does not feel, the lumps disappear, and the breast cancer of a patient is cured after the hospital diagnosis.

Typical case 2

Wu-Chi, female, age 39, self-sensed nipple discharge, breast skin and areola abnormality and breast pain, the breast cancer is diagnosed as breast cancer by a hospital, the breast cancer is treated by an operation at first and then is treated by chemotherapy, patients are distressed, side effects are serious, vomiting and alopecia are caused, and the disease condition is not improved, then the pure traditional Chinese medicine transdermal liniment prepared by the invention is used, the liniment is applied for 3 times every day, after two continuous treatment courses, clinical symptoms are relieved, after two continuous treatment courses, nipple discharge symptoms disappear, the breast skin and the areola recover to be normal, and no pain is caused, and the breast cancer of the patients is cured by the hospital diagnosis.

Typical case 3

When Qiaoji, women and 59 years old are in self-service, the breast is sensed to have lumps, abnormal nipples and swollen lymph nodes with stabbing pain, the pure traditional Chinese medicine transdermal liniment prepared by the invention is applied for 3 times every day, after two continuous treatment courses, the lumps in the breast are obviously reduced, the nipples tend to be normal, the swollen lymph nodes are relieved, the stabbing pain is relieved, after three continuous treatment courses, the lumps are eliminated, the nipples and the lymph nodes are recovered to be normal, and the breast cancer of a patient is cured after hospital diagnosis.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The pure traditional Chinese medicine transdermal liniment for treating breast cancer is characterized by comprising the following raw materials in parts by weight: 15-20 parts of alkanna tinctoria root, 15-20 parts of honeysuckle, 15-20 parts of Chinese violet, 10-12 parts of turmeric root-tuber, 10-12 parts of pangolin scales, 15-18 parts of angelica dahurica, 6-9 parts of scorpion, 9-12 parts of saffron crocus, 9-12 parts of ground beeltle and 3-6 parts of snow lotus herb.

2. The pure traditional Chinese medicine transdermal liniment for treating breast cancer according to claim 1 is characterized by comprising the following raw materials in parts by weight: 15 parts of alkanna tinctoria root, 15 parts of honeysuckle, 15 parts of Chinese violet, 10 parts of turmeric root-tuber, 10 parts of pangolin scales, 15 parts of dahurian angelica root, 6 parts of scorpion, 9 parts of saffron, 9 parts of ground beetle and 3 parts of snow lotus herb.

3. The pure traditional Chinese medicine transdermal liniment for treating breast cancer according to claim 1 is characterized by comprising the following raw materials in parts by weight: 17 parts of alkanna tinctoria root, 18 parts of honeysuckle, 17 parts of Chinese violet, 11 parts of turmeric root-tuber, 11 parts of pangolin scales, 16 parts of dahurian angelica root, 7 parts of scorpion, 10 parts of saffron, 10 parts of ground beetle and 5 parts of snow lotus herb.

4. The pure traditional Chinese medicine transdermal liniment for treating breast cancer according to claim 1 is characterized by comprising the following raw materials in parts by weight: 20 parts of alkanna tinctoria root, 20 parts of honeysuckle, 20 parts of Chinese violet, 12 parts of turmeric root-tuber, 12 parts of pangolin scales, 18 parts of dahurian angelica root, 9 parts of scorpion, 12 parts of saffron, 12 parts of ground beeltle and 6 parts of snow lotus herb.

5. A method for preparing a pure Chinese medicinal transdermal liniment for treating breast cancer as claimed in any one of claims 1 to 4, which comprises the following steps:

(1) putting the root of Chinese violet, honeysuckle, Chinese violet, turmeric root-tuber, pangolin scales, dahurian angelica root, scorpion, saffron, ground beetle and snow lotus herb in parts by weight into a stone mortar, and pounding the mixture into powder;

(2) the mashed mixed powder is put into 50 to 100 weight parts of alcohol to be soaked for 20 to 25 days for use.

6. The preparation method of the pure traditional Chinese medicine transdermal liniment for treating breast cancer according to claim 5 is characterized in that: the alcohol concentration in the step (2) is 75%.