CN112368010A - 抗微生物的、细菌噬菌体来源的多肽及其针对革兰氏阴性细菌的用途 - Google Patents

抗微生物的、细菌噬菌体来源的多肽及其针对革兰氏阴性细菌的用途 Download PDF

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CN112368010A
CN112368010A CN201980036013.5A CN201980036013A CN112368010A CN 112368010 A CN112368010 A CN 112368010A CN 201980036013 A CN201980036013 A CN 201980036013A CN 112368010 A CN112368010 A CN 112368010A
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negative bacteria
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R·舒赫
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Contrafect Corp
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Contrafect Corp
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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CN201980036013.5A 2018-03-29 2019-03-29 抗微生物的、细菌噬菌体来源的多肽及其针对革兰氏阴性细菌的用途 Pending CN112368010A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862650235P 2018-03-29 2018-03-29
US62/650235 2018-03-29
PCT/US2019/024854 WO2019191598A1 (en) 2018-03-29 2019-03-29 Antimicrobial, bacteriophage-derived polypeptides and their use against gram-negative bacteria

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CN112368010A true CN112368010A (zh) 2021-02-12

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US (1) US20210330738A1 (https=)
EP (1) EP3773669A4 (https=)
JP (1) JP2021519311A (https=)
KR (1) KR20210005027A (https=)
CN (1) CN112368010A (https=)
AU (1) AU2019245333A1 (https=)
BR (1) BR112020019010A2 (https=)
CA (1) CA3096236A1 (https=)
IL (1) IL277399A (https=)
MX (1) MX2020010071A (https=)
WO (1) WO2019191598A1 (https=)

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Publication number Priority date Publication date Assignee Title
WO2019191633A2 (en) 2018-03-29 2019-10-03 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
KR20220029746A (ko) * 2019-07-05 2022-03-08 콘트라펙트 코포레이션 항미생물성 박테리오파지 유도된 폴리펩타이드 및 이의 그람 음성 및 항산성 세균에 대한 사용
EP4058468A4 (en) * 2019-11-14 2024-04-10 Contrafect Corporation POLYPEPTIDE CONSTRUCTIONS OF ANTIMICROBIAL PEPTIDE LYSINE (AMP), LYSINES, ISOLATED POLYNUCLEOTIDES ENCODING THEREFOR AND USES THEREOF
WO2021211303A1 (en) * 2020-04-14 2021-10-21 Contrafect Corporation Antiviral, bacteriophage-derived polypeptides and their use against viruses

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CA2447823A1 (en) * 2001-05-23 2002-11-28 The University Of British Columbia Diagnosis of vascular disease susceptibility using bacteriophage phi-cpn1 host chlamydia
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KR20090115852A (ko) * 2007-01-19 2009-11-09 카이 파마슈티컬즈 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형
WO2010141135A2 (en) * 2009-03-05 2010-12-09 Trustees Of Boston University Bacteriophages expressing antimicrobial peptides and uses thereof
US20150315259A1 (en) * 2012-03-19 2015-11-05 Madeleine Phamaceuticals Pty Ltd Method of producing a recombinant peptide
EP4115897A1 (en) * 2015-09-17 2023-01-11 Contrafect Corporation Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby
WO2019191633A2 (en) * 2018-03-29 2019-10-03 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
EP3840771A4 (en) * 2018-08-23 2023-04-19 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof
KR20220029746A (ko) * 2019-07-05 2022-03-08 콘트라펙트 코포레이션 항미생물성 박테리오파지 유도된 폴리펩타이드 및 이의 그람 음성 및 항산성 세균에 대한 사용
EP4058468A4 (en) * 2019-11-14 2024-04-10 Contrafect Corporation POLYPEPTIDE CONSTRUCTIONS OF ANTIMICROBIAL PEPTIDE LYSINE (AMP), LYSINES, ISOLATED POLYNUCLEOTIDES ENCODING THEREFOR AND USES THEREOF
US20210324359A1 (en) * 2020-04-17 2021-10-21 Contrafect Corporation Use of gram-negative lysin-antimicrobial peptide (amp) polypeptide constructs in treating endocarditis

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MX2020010071A (es) 2021-01-08
AU2019245333A1 (en) 2020-10-29
KR20210005027A (ko) 2021-01-13
RU2020131450A (ru) 2022-04-29
WO2019191598A1 (en) 2019-10-03
EP3773669A1 (en) 2021-02-17
CA3096236A1 (en) 2019-10-03
US20210330738A1 (en) 2021-10-28
JP2021519311A (ja) 2021-08-10
EP3773669A4 (en) 2022-04-27
BR112020019010A2 (pt) 2020-12-29
IL277399A (en) 2020-11-30

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Application publication date: 20210212