CN112336881B - Continuous sterilizing device and process - Google Patents
Continuous sterilizing device and process Download PDFInfo
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- CN112336881B CN112336881B CN202011214621.1A CN202011214621A CN112336881B CN 112336881 B CN112336881 B CN 112336881B CN 202011214621 A CN202011214621 A CN 202011214621A CN 112336881 B CN112336881 B CN 112336881B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
- A61L2/06—Hot gas
- A61L2/07—Steam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/02—Treatment of water, waste water, or sewage by heating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
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Abstract
The invention discloses a continuous sterilizing device and a process, wherein the continuous sterilizing device sequentially comprises a proportioning tank, a waste heat recovery device, a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank; a valve I, a pump I and a flow sensor are sequentially connected between the batching tank and the waste heat recovery device through pipelines; the continuous sterilizing process sequentially comprises an empty tank sterilizing step, a culture medium sterilizing step and a water sterilizing step. The pressure of the material B is higher than that of the material A, and the pressure of the material B is higher than that of cooling water in the cooling heat exchanger, so that the occurrence probability of bacteria contamination is reduced. In addition, the establishment of the waste heat recovery device ensures that the process is more energy-saving and time-saving; steam passes through the indirect heating of spiral plate heat exchanger, can not produce noise and vibrations, has purified operational environment, and the fluctuation of vapor simultaneously causes the cooling phenomenon to influence less to the material, has guaranteed the stability of material sterilization temperature relatively to material B's aseptic quality has been guaranteed.
Description
Technical Field
The invention relates to the technical field of biological fermentation, in particular to a continuous sterilizing device and a continuous sterilizing process.
Background
Only a single production strain can be cultured in the fermentation production culture process, other microorganisms cannot exist in the fermentation tank, and if other mixed bacteria are found in the fermentation process by microscopic examination or plate culture, the condition is called fermentation contamination. The sterilization method commonly used in the existing fermentation production mainly comprises steam moist heat sterilization, dry heat sterilization, ultraviolet sterilization, chemical agent sterilization and the like. The steam sterilization method is a practical and wide sterilization method with obvious effect, and generally has two modes: a solid can sterilization mode and a continuous sterilization mode.
Continuous sterilization is often used in actual production, and continuous disinfection and sterilization (also called continuous sterilization) is to continuously feed a prepared and preheated culture medium into a heating tower heated by direct steam by a pump to reach a sterilization temperature in a short time, then feed the culture medium into a maintenance tank (or a maintenance pipe), maintain the culture medium at the sterilization temperature for a period of time, feed the culture medium into a cooling pipe, cool the culture medium to an inoculation temperature, and directly feed the culture medium into a fermentation tank which is sterilized in advance (empty tank sterilization).
The continuous disinfection and sterilization process has the characteristics of strong continuity, high disinfection and sterilization speed, less damage of nutrient components of the culture medium and the like. But the adoption of the continuous sterilization mode easily increases the contamination probability, has large energy consumption and has higher requirement on steam.
Disclosure of Invention
In order to solve the above problems, a first aspect of the present invention provides a continuous sterilizing device, which sequentially comprises a dosing tank, a waste heat recovery device, a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank; connect gradually through the pipeline between batching jar and the waste heat recovery device and be equipped with valve I, pump I, flow sensor.
As a preferred technical scheme, the waste heat recovery device comprises a waste heat recovery heat exchanger, a pressure sensor is arranged above a material A pipe of the waste heat recovery heat exchanger, a back pressure valve is arranged below the material A pipe, and the back pressure valve I is connected with a steam heating device through a pipeline.
As a preferred technical scheme, the steam heating device comprises a pump II, an outlet of the pump II is connected with an inlet of the steam heating heat exchanger, a temperature sensor I is arranged at an outlet of the steam heating heat exchanger, and the temperature sensor I is connected with the temperature maintaining device through a pipeline.
As a preferable technical scheme, the pump II is arranged behind the back pressure valve I and in front of the steam heating heat exchanger.
As an optimal technical scheme, the temperature maintaining device comprises a temperature maintaining heat exchanger, one end of the temperature maintaining heat exchanger is connected with a temperature sensor I, the other end of the temperature maintaining heat exchanger is connected with a material B pipe of the waste heat recovery heat exchanger, a back pressure valve II is arranged at an outlet of the material B pipe, and the material B enters the cooling device through the back pressure valve II.
As a preferred technical scheme, the cooling device includes the cooling heat exchanger, the entry of cooling heat exchanger passes through the pipeline and is connected with back pressure valve II, temperature sensor II, back pressure valve III have been set gradually in the exit of cooling heat exchanger, back pressure valve III passes through the pipeline and links to each other with the fermentation cylinder, the bottom of fermentation cylinder has set gradually pump III, valve II.
The second aspect of the invention also provides a process for utilizing the continuous sterilizing device, which sequentially comprises an empty tank sterilizing step, a culture medium sterilizing step and a water sterilizing step, and specifically comprises the following operations:
s1, empty tank sterilization: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank are subjected to air digestion for 25-50 min at the temperature of 125-130 ℃ and the pressure of 0.25-0.3 Mpa;
s2, a culture medium sterilization step: pumping the materials into a continuous sterilizing device by a pump, sterilizing for 6-10 min at 120-140 ℃ under the pressure of 0.1-0.5 MPa, quickly cooling to 35-45 ℃, and then feeding into a fermentation tank;
s3, water sterilization: and after the culture medium is sterilized, pumping tap water into the fermentation tank by using a pump for sterilization, adding the fermentation tank until the process water consumption is reached, immediately closing a valve on the fermentation tank, and simultaneously closing the pump I and the pump II.
As a preferred technical scheme, the continuous sterilization process sequentially comprises an empty tank sterilization step, a culture medium sterilization step and a water sterilization step, and the detailed steps are as follows:
s1, empty tank sterilization: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank are subjected to air digestion for 25-50 min at the temperature of 125-130 ℃ and the pressure of 0.25-0.3 Mpa;
s2, a culture medium sterilization step: the material is pumped into a material A pipe in the waste heat recovery heat exchanger through a pump I to obtain a material A; the material A passes through a back pressure valve I, enters a steam heating heat exchanger through a pump II, enters a temperature maintaining heat exchanger for sterilization, and is sterilized for 6-10 min at the temperature of 120-140 ℃ and the pressure of 0.1-0.5 MPa to obtain a material B; the material B enters a material B pipe in the waste heat recovery heat exchanger after coming out of the temperature maintaining heat exchanger, enters a cooling heat exchanger after passing through a back pressure valve II, is rapidly cooled to 35-45 ℃, and then enters a fermentation tank through a back pressure valve III;
s3, water sterilization: after the culture medium is sterilized, rapidly pumping tap water into a material A pipe in the waste heat recovery heat exchanger by using a pump I, entering a steam heating heat exchanger through a back pressure valve I by using a pump II, entering a temperature maintenance heat exchanger for sterilization, and sterilizing for 6-10 min at the temperature of 120-140 ℃ and under the pressure of 0.1-0.5 MPa; and (3) feeding the material B from the temperature maintaining heat exchanger into a waste heat recovery heat exchanger, feeding the material B into a cooling heat exchanger through a back pressure valve II, rapidly cooling to 35-45 ℃, feeding the material B into a fermentation tank through a back pressure valve III, supplementing the fermentation tank to the process water consumption, immediately closing a valve on the fermentation tank, and simultaneously closing a pump I and a pump II.
As a preferred technical solution, the pressure applied to the material B is higher than the pressure applied to the material a.
As a preferable technical scheme, the pressure of the material B is higher than the pressure of cooling water in the cooling heat exchanger.
Has the beneficial effects that:
when the continuous sterilizing system is in a working state, the occurrence probability of bacteria contamination is reduced by setting the pressure of the material B to be higher than the pressure of the material A and higher than the pressure of cooling water in the cooling heat exchanger. In addition, the establishment of the waste heat recovery device ensures that the process is more energy-saving and time-saving; steam passes through the indirect heating of spiral plate heat exchanger, can not produce noise and vibrations, has purified operational environment, and workman convenient operation, the condition is superior, and the fluctuation of vapor simultaneously causes the cooling phenomenon to influence lessly to the material, has guaranteed the stability of material sterilization temperature relatively to material B's aseptic quality has been guaranteed.
Drawings
In order to more clearly illustrate the embodiments or technical solutions in the prior art of the present invention, the drawings used in the description of the embodiments or prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained based on these drawings without creative efforts.
FIG. 1 is a schematic view of the continuous sterilizing apparatus of the present invention.
The system comprises a dosing tank 1, a valve I2, a valve I3, a pump I, a flow sensor 4, a pressure sensor 5, a back pressure valve I6, a pump II 7, a temperature sensor I8, a back pressure valve II 9, a temperature sensor II 10, a back pressure valve III 11, a fermentation tank 12, a pump III, a valve II 14, a waste heat recovery heat exchanger A, a steam heating heat exchanger B, a temperature maintaining heat exchanger C and a cooling heat exchanger D.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
In order to solve the above problems, a first aspect of the present invention provides a continuous sterilizing device, which sequentially comprises a dosing tank, a waste heat recovery device, a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank; connect gradually through the pipeline between batching jar and the waste heat recovery device and be equipped with valve I, pump I, flow sensor.
The flow sensor is used to control the flow of the entire system.
In some preferred embodiments, the waste heat recovery device comprises a waste heat recovery heat exchanger, a pressure sensor is arranged above a material A pipe of the waste heat recovery heat exchanger, a back pressure valve is arranged below the material A pipe, and the back pressure valve I is connected with the steam heating device through a pipeline.
In some preferred embodiments, the steam heating device comprises a pump ii, an outlet of the pump ii is connected with an inlet of the steam heating heat exchanger, and a temperature sensor i is arranged at an outlet of the steam heating heat exchanger and connected with the temperature maintaining device through a pipeline.
In some preferred embodiments, the pump ii is disposed after the backpressure valve i and before the steam heating heat exchanger. Set up pump II behind back pressure valve I, it is in order to improve the sterilization rate before the steam heating heat exchanger, when pump II was arranged in after the steam heating, can cause the incomplete drawback of sterilization disinfection.
In some preferred embodiments, the temperature maintaining device comprises a temperature maintaining heat exchanger, one end of the temperature maintaining heat exchanger is connected with the temperature sensor I, the other end of the temperature maintaining heat exchanger is connected with a material B pipe of the waste heat recovery heat exchanger, a back pressure valve II is arranged at an outlet of the material B pipe, and the material B enters the cooling device through the back pressure valve II.
In some preferred embodiments, the cooling device includes cooling heat exchanger, cooling heat exchanger's entry is passed through the pipeline and is connected with back pressure valve II, temperature sensor II, back pressure valve III have been set gradually in cooling heat exchanger's exit, back pressure valve III passes through the pipeline and links to each other with the fermentation cylinder, the bottom of fermentation cylinder has set gradually pump III, valve II.
The second aspect of the invention also provides a process for utilizing the continuous sterilizing device, which sequentially comprises an empty tank sterilizing step, a culture medium sterilizing step and a water sterilizing step, and specifically comprises the following operations:
s1, an empty can sterilization step: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank are subjected to air digestion for 25-50 min at the temperature of 125-130 ℃ and the pressure of 0.25-0.3 Mpa;
s2, a culture medium sterilization step: pumping the materials into a continuous sterilizing device by a pump, sterilizing for 6-10 min at the temperature of 120-140 ℃ and under the pressure of 0.1-0.5 MPa, quickly cooling to 35-45 ℃, and then feeding into a fermentation tank;
s3, water sterilization: and after the culture medium is sterilized, pumping tap water into the fermentation tank by using a pump for sterilization, adding the fermentation tank until the process water consumption is reached, immediately closing a valve on the fermentation tank, and simultaneously closing the pump I and the pump II.
In some preferred embodiments, the continuous sterilization process sequentially comprises an empty tank sterilization step, a culture medium sterilization step and a water sterilization step, and the detailed steps are as follows:
s1, empty tank sterilization: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank are subjected to air digestion for 25-50 min at the temperature of 125-130 ℃ and the pressure of 0.25-0.3 Mpa;
s2, a culture medium sterilization step: the material is pumped into a material A pipe in the waste heat recovery heat exchanger through a pump I to obtain a material A; the material A passes through a back pressure valve I, enters a steam heating heat exchanger through a pump II, enters a temperature maintenance heat exchanger for sterilization, and is sterilized for 6-10 min at the temperature of 120-140 ℃ and under the pressure of 0.1-0.5 MPa to obtain a material B; the material B enters a material B pipe in the waste heat recovery heat exchanger after coming out of the temperature maintaining heat exchanger, enters the cooling heat exchanger after passing through a back pressure valve II, is rapidly cooled to 35-45 ℃, and then enters a fermentation tank through a back pressure valve III;
s3, water sterilization: after the culture medium is sterilized, rapidly pumping tap water into a material A pipe in the waste heat recovery heat exchanger by using a pump I, entering a steam heating heat exchanger through a back pressure valve I by using a pump II, entering a temperature maintenance heat exchanger for sterilization, and sterilizing for 6-10 min at the temperature of 120-140 ℃ under the pressure of 0.1-0.5 MPa; and (3) feeding the material B from the temperature maintaining heat exchanger into a waste heat recovery heat exchanger, feeding the material B into a cooling heat exchanger through a back pressure valve II, rapidly cooling to 35-45 ℃, feeding the material B into a fermentation tank through a back pressure valve III, supplementing the fermentation tank to the process water consumption, immediately closing a valve on the fermentation tank, and simultaneously closing a pump I and a pump II.
In some preferred embodiments, the pressure to which material B is subjected is higher than the pressure to which material a is subjected.
In some preferred embodiments, the pressure of the material B is higher than that of cooling water in the cooling and temperature-reducing heat exchanger.
The pump I and the pressure sensor form a pressure stabilizing system, the pressure environment of the material A can be controllably adjusted through the combined action of the pump I, the pressure sensor and the backpressure valve I, the utilization rate of heat in the waste heat recovery heat exchanger can be improved when the pressure of the backpressure valve I is adjusted to a higher value, the material A is enabled to have a higher temperature before entering the steam heating heat exchanger, the energy consumption output in the production process is further reduced, and the energy-saving effect is achieved; the materials and the high-temperature hot water circulate and exchange heat with each other in a closed system all the time, so that the heat energy is fully utilized, and the energy, the water and the time are saved.
The combined action of the pump II, the back pressure valve II and the back pressure valve III can reduce the occurrence probability of bacteria contamination in the continuous disinfection process production, and the reason is that the pressure borne by the material B is higher than that of the material A by adjusting the pump II and the back pressure valve II, so when the dividing wall between the material A and the material B is damaged, the material B can only migrate into the material A under the action of the pressure, namely the material A is prevented from entering the material B, and the probability of bacteria contamination of the material B is reduced; make material B pressurized pressure be higher than the pressure that the cooling water receives through regulating pump II, back pressure valve III, reduced material B on the one hand by the probability that the cooling water infects the fungus, on the other hand has still strengthened the heat exchange rate to energy-conserving effect has been improved.
Examples
The technical solution of the present invention is described in detail by the following examples, but the scope of the present invention is not limited to the examples. Unless otherwise specified, all the raw materials in the present invention are commercially available.
Example 1
Embodiment 1 provides a continuous sterilizing device, which comprises a dosing tank 1, a waste heat recovery device, a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank 12 in sequence; connect gradually through the pipeline between batching jar 1 and the waste heat recovery device and be equipped with valve I2, pump I3, flow sensor 4.
The waste heat recovery device comprises a waste heat recovery heat exchanger A, a pressure sensor 5 is arranged above a material A pipe of the waste heat recovery heat exchanger A, a back pressure valve I6 is arranged below the material A pipe, and the back pressure valve I6 is connected with the steam heating device through a pipeline.
Steam heating device includes pump II 7, the exit of pump II 7 and steam heating heat exchanger B's entry linkage, steam heating heat exchanger B's exit is provided with temperature sensor I8, temperature sensor I8 is connected with temperature maintenance device through the pipeline. And the pump II 7 is arranged behind the backpressure valve I6 and in front of the steam heating heat exchanger B.
The temperature maintaining device comprises a temperature maintaining heat exchanger C, one end of the temperature maintaining heat exchanger C is connected with a temperature sensor I8, the other end of the temperature maintaining heat exchanger C is connected with a material B pipe of the waste heat recovery heat exchanger, a back pressure valve II 9 is arranged at an outlet of the material B pipe, and the material B enters the cooling device through the back pressure valve II 9.
The cooling device comprises a cooling heat exchanger D, the inlet of the cooling heat exchanger D is connected with a back pressure valve II 9 through a pipeline, the outlet of the cooling heat exchanger D is sequentially provided with a temperature sensor II 10 and a back pressure valve III 11, the back pressure valve III 11 is connected with a fermentation tank 12 through a pipeline, and the bottom end of the fermentation tank 12 is sequentially provided with a pump III 13 and a valve II 14.
Example 2
s1, empty tank sterilization: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank 12 are subjected to air digestion for 25min at 125 ℃ and 0.25Mpa by using steam;
s2, a culture medium sterilization step: the method comprises the following steps of (1) loading materials into a batching tank 1, opening a valve I2, and pumping the materials into a material A pipe in a waste heat recovery heat exchanger A through a pump I3 to obtain a material A; the material A passes through a back pressure valve I6, enters a steam heating heat exchanger B through a pump II 7, enters a temperature maintenance heat exchanger C for sterilization, and is sterilized for 6min at the temperature of 120 ℃ and the pressure of 0.5MPa to obtain a material B; the material B comes out of the temperature maintaining heat exchanger C, enters a material B pipe of the waste heat recovery heat exchanger A, enters a cooling heat exchanger D after passing through a back pressure valve II 9, is rapidly cooled to 35 ℃, and then enters a fermentation tank 12 through a back pressure valve III 11;
s3, water sterilization: after the culture medium is sterilized, rapidly pumping tap water into a material A pipe in the waste heat recovery heat exchanger A by using a pump I3, entering a steam heating heat exchanger B by using a pump II 7 after passing through a back pressure valve I6, then entering a temperature maintenance heat exchanger C for sterilization, and sterilizing for 6min at the temperature of 120 ℃ and under the pressure of 0.5 MPa; the material B pipe that gets into among the waste heat recovery heat exchanger A after keeping heat exchanger C from the temperature and coming into after II 9 back pressure valves gets into cooling heat exchanger D, gets into fermentation cylinder 12 through back pressure valve III 11 after cooling to 35 ℃ rapidly, after the supplementary fermentation cylinder 12 reaches the process water consumption, closes the last valve of fermentation cylinder 12 immediately, and it can to close pump I3, pump II 7 simultaneously.
Example 3
s1, empty tank sterilization: the steam heating device, the temperature maintaining device, the cooling device and the fermentation tank 12 are subjected to air digestion for 50min at 130 ℃ and 0.3Mpa by using steam;
s2, a culture medium sterilization step: the method comprises the following steps of (1) loading materials into a batching tank 1, opening a valve I2, and pumping the materials into a material A pipe in a waste heat recovery heat exchanger A through a pump I3 to obtain a material A; the material A passes through a back pressure valve I6, enters a steam heating heat exchanger B through a pump II 7, enters a temperature maintenance heat exchanger C for sterilization, and is sterilized for 10min at the temperature of 140 ℃ and the pressure of 0.4MPa to obtain a material B; the material B comes out of the temperature maintaining heat exchanger C and then enters a material B pipe in the waste heat recovery heat exchanger A, enters a cooling heat exchanger D after passing through a back pressure valve II 9, is rapidly cooled to 345 ℃, and then enters a fermentation tank 12 through a back pressure valve III 11;
s3, water sterilization: after the culture medium is sterilized, rapidly pumping tap water into a material A pipe in the waste heat recovery heat exchanger A by using a pump I3, entering a steam heating heat exchanger B by using a pump II 7 after passing through a back pressure valve I6, then entering a temperature maintenance heat exchanger C for sterilization, and sterilizing for 10min at the temperature of 140 ℃ and under the pressure of 0.4 MPa; and the material B pipe enters the waste heat recovery heat exchanger A after coming out of the temperature maintenance heat exchanger C, enters the cooling heat exchanger D after passing through the back pressure valve II 9, is rapidly cooled to 45 ℃ and then enters the fermentation tank 12 through the back pressure valve III 11, the upper valve of the fermentation tank 12 is immediately closed after the fermentation tank 12 is supplemented to the process water consumption, and meanwhile, the pump I3 and the pump II 7 are closed.
Claims (5)
1. A continuous sterilizing device is characterized by sequentially comprising a proportioning tank, a waste heat recovery device, a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank; a valve I, a pump I and a flow sensor are sequentially connected between the batching tank and the waste heat recovery device through pipelines;
the waste heat recovery device comprises a waste heat recovery heat exchanger, a pressure sensor is arranged above a material A pipe of the waste heat recovery heat exchanger, a back pressure valve I is arranged below the material A pipe of the waste heat recovery heat exchanger, and the back pressure valve I is connected with the steam heating device through a pipeline; the steam heating device comprises a pump II, an outlet of the pump II is connected with an inlet of the steam heating heat exchanger, a temperature sensor I is arranged at an outlet of the steam heating heat exchanger, and the temperature sensor I is connected with the temperature maintaining device through a pipeline; the pump II is arranged behind the backpressure valve I and in front of the steam heating heat exchanger; the temperature maintaining device comprises a temperature maintaining heat exchanger, one end of the temperature maintaining heat exchanger is connected with the temperature sensor I, the other end of the temperature maintaining heat exchanger is connected with a material B pipe of the waste heat recovery heat exchanger, a back pressure valve II is arranged at an outlet of the material B pipe, and the material B enters the cooling device through the back pressure valve II;
the pressure of the material B is higher than that of the material A.
2. The continuous sterilizing device according to claim 1, wherein the cooling device comprises a cooling heat exchanger, an inlet of the cooling heat exchanger is connected with a back pressure valve II through a pipeline, an outlet of the cooling heat exchanger is sequentially provided with a temperature sensor II and a back pressure valve III, the back pressure valve III is connected with the fermentation tank through a pipeline, and a pump III and a valve II are sequentially arranged at the bottom end of the fermentation tank.
3. A process for using the continuous sterilizing device of any one of claims 1-2, which comprises the steps of empty tank sterilization, culture medium sterilization and water sterilization in sequence, and comprises the following specific operations:
s1, empty tank sterilization: a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank are used for air-cooling for 25 to 50min under the conditions of 125 to 130 ℃ and 0.25 to 0.3 Mpa;
s2, a culture medium sterilization step: pumping the materials into a continuous sterilizing device by a pump, sterilizing for 6 to 10min at the temperature of between 120 and 140 ℃ and under the pressure of between 0.1 and 0.5MPa, quickly cooling to 35 to 45 ℃, and then entering a fermentation tank;
s3, water sterilization: after the culture medium is sterilized, pumping tap water into the fermentation tank by a pump for sterilization, adding the fermentation tank until the process water consumption is reached, immediately closing a valve on the fermentation tank, and simultaneously closing the pump I and the pump II.
4. The process of claim 3, which comprises the steps of empty tank sterilization, culture medium sterilization and water sterilization in sequence, and comprises the following detailed steps:
s1, an empty can sterilization step: a steam heating device, a temperature maintaining device, a cooling device and a fermentation tank are used for air-cooling for 25 to 50min under the conditions of 125 to 130 ℃ and 0.25 to 0.3 Mpa;
s2, a culture medium sterilization step: the material is pumped into a material A pipe in the waste heat recovery heat exchanger through a pump I to obtain a material A; after passing through a back pressure valve I, a material A enters a steam heating heat exchanger through a pump II, then enters a temperature maintaining heat exchanger for sterilization, and is sterilized for 6 to 10min at the temperature of between 120 and 140 ℃ and under the pressure of between 0.1 and 0.5MPa to obtain a material B; the material B comes out of the temperature maintaining heat exchanger and then enters a material B pipe in the waste heat recovery heat exchanger, enters the cooling heat exchanger through a back pressure valve II, is rapidly cooled to 35-45 ℃, and then enters the fermentation tank through a back pressure valve III;
s3, water sterilization: after the culture medium is sterilized, rapidly pumping tap water into a material pipe A in a waste heat recovery heat exchanger by using a pump I, enabling the material pipe A to enter a steam heating heat exchanger through a back pressure valve I and then enter a temperature maintenance heat exchanger for sterilization by using a pump II, and sterilizing for 6 to 10min at the temperature of 120-140 ℃ and under the pressure of 0.1-0.5 MPa; and (3) feeding the material B from the temperature maintaining heat exchanger into a material B pipe in the waste heat recovery heat exchanger, feeding the material B pipe into a cooling heat exchanger through a back pressure valve II, rapidly cooling to 35-45 ℃, feeding the material B pipe into a fermentation tank through a back pressure valve III, supplementing the fermentation tank to the process water consumption, immediately closing a valve on the fermentation tank, and simultaneously closing a pump I and a pump II.
5. The process for utilizing a continuous sterilizing device as claimed in claim 4, wherein the pressure of the material B is higher than that of cooling water in the cooling heat exchanger.
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