CN112322735A - 用于前列腺癌复发的预后的基因表达面板 - Google Patents
用于前列腺癌复发的预后的基因表达面板 Download PDFInfo
- Publication number
- CN112322735A CN112322735A CN202011258642.3A CN202011258642A CN112322735A CN 112322735 A CN112322735 A CN 112322735A CN 202011258642 A CN202011258642 A CN 202011258642A CN 112322735 A CN112322735 A CN 112322735A
- Authority
- CN
- China
- Prior art keywords
- prostate cancer
- marker genes
- individual
- predictive model
- progression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461928361P | 2014-01-16 | 2014-01-16 | |
| US61/928,361 | 2014-01-16 | ||
| CN201580004797.5A CN105917008B (zh) | 2014-01-16 | 2015-01-16 | 用于前列腺癌复发的预后的基因表达面板 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580004797.5A Division CN105917008B (zh) | 2014-01-16 | 2015-01-16 | 用于前列腺癌复发的预后的基因表达面板 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112322735A true CN112322735A (zh) | 2021-02-05 |
Family
ID=52435027
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580004797.5A Active CN105917008B (zh) | 2014-01-16 | 2015-01-16 | 用于前列腺癌复发的预后的基因表达面板 |
| CN202011258642.3A Pending CN112322735A (zh) | 2014-01-16 | 2015-01-16 | 用于前列腺癌复发的预后的基因表达面板 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580004797.5A Active CN105917008B (zh) | 2014-01-16 | 2015-01-16 | 用于前列腺癌复发的预后的基因表达面板 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10364469B2 (enExample) |
| EP (1) | EP3094747B1 (enExample) |
| JP (1) | JP6666852B2 (enExample) |
| CN (2) | CN105917008B (enExample) |
| AU (3) | AU2015206336B2 (enExample) |
| CA (1) | CA2935720A1 (enExample) |
| WO (1) | WO2015109234A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10364469B2 (en) | 2014-01-16 | 2019-07-30 | Illumina, Inc | Gene expression panel for prognosis of prostate cancer recurrence |
| WO2019018684A1 (en) * | 2017-07-21 | 2019-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS |
| IL319255A (en) | 2017-08-07 | 2025-04-01 | Univ Johns Hopkins | Methods and materials for cancer assessment and treatment |
| CN107699564B (zh) * | 2017-10-23 | 2019-09-20 | 中国科学院苏州生物医学工程技术研究所 | 人前列腺癌早期诊断用长链非编码rna序列及其应用 |
| US10769783B2 (en) * | 2018-02-09 | 2020-09-08 | Case Western Reserve University | Predicting prostate cancer biochemical recurrence using combined nuclear NF-KB/P65 localization and gland morphology |
| DE202019005627U1 (de) | 2018-04-02 | 2021-05-31 | Grail, Inc. | Methylierungsmarker und gezielte Methylierungssondenpanels |
| US11348239B2 (en) | 2018-05-14 | 2022-05-31 | Tempus Labs, Inc. | Predicting total nucleic acid yield and dissection boundaries for histology slides |
| US10957041B2 (en) | 2018-05-14 | 2021-03-23 | Tempus Labs, Inc. | Determining biomarkers from histopathology slide images |
| US11741365B2 (en) | 2018-05-14 | 2023-08-29 | Tempus Labs, Inc. | Generalizable and interpretable deep learning framework for predicting MSI from histopathology slide images |
| US11348240B2 (en) * | 2018-05-14 | 2022-05-31 | Tempus Labs, Inc. | Predicting total nucleic acid yield and dissection boundaries for histology slides |
| US11348661B2 (en) | 2018-05-14 | 2022-05-31 | Tempus Labs, Inc. | Predicting total nucleic acid yield and dissection boundaries for histology slides |
| AU2019351130B2 (en) | 2018-09-27 | 2025-10-23 | GRAIL, Inc | Methylation markers and targeted methylation probe panel |
| US12325879B2 (en) | 2018-10-31 | 2025-06-10 | Regents Of The University Of Minnesota | Methods for predicting a response to bevacizumab or platinum-based chemotherapy or both in patients with ovarian cancer |
| CA3126990A1 (en) * | 2019-02-14 | 2020-08-20 | Maneesh Jain | Methods and systems for determining a pregnancy-related state of a subject |
| WO2020225551A1 (en) * | 2019-05-08 | 2020-11-12 | Oxford BioDynamics PLC | Chromosome conformation markers of prostate cancer and lymphoma |
| CN110706749B (zh) * | 2019-09-10 | 2022-06-10 | 至本医疗科技(上海)有限公司 | 一种基于组织器官分化层次关系的癌症类型预测系统和方法 |
| GB201915464D0 (en) * | 2019-10-24 | 2019-12-11 | Uea Enterprises Ltd | Novel biomarkers and diagnostic profiles for prostate cancer |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| KR102139313B1 (ko) * | 2020-02-27 | 2020-07-29 | 이화여자대학교 산학협력단 | 알츠하이머병 치매 조기 진단을 위한 후성 유전학적 진단 키트 개발 |
| KR102139315B1 (ko) * | 2020-02-27 | 2020-07-29 | 이화여자대학교 산학협력단 | Tnfrsf19 유전자의 dna 메틸레이션 변화를 이용한 알츠하이머병 치매 조기진단 마커 |
| WO2021253134A1 (en) * | 2020-06-18 | 2021-12-23 | Ontario Institute For Cancer Research (Oicr) | Molecular classifiers for prostate cancer |
| EP3960877A1 (en) * | 2020-08-31 | 2022-03-02 | Koninklijke Philips N.V. | Prediction of a response of a prostate cancer subject to therapy or personalization of therapy of a prostate cancer subject |
| WO2022147503A1 (en) * | 2020-12-31 | 2022-07-07 | Tempus Labs, Inc. | Predicting total nucleic acid yield and dissection boundaries for histology slides |
| WO2023058100A1 (ja) | 2021-10-04 | 2023-04-13 | 国立大学法人 東京大学 | 構造多型の検出方法、プライマーセット及びプライマーセットの設計方法 |
| WO2024229244A2 (en) * | 2023-05-03 | 2024-11-07 | Mirvie, Inc. | Methods and systems for determining a pregnancy-related state of a subject |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006066965A2 (en) * | 2004-12-24 | 2006-06-29 | Stichting, Katholieke Universiteit, The Universitymedical | Mrna ratios in urinary sediments and/or urine as a prognostic and/or theranostic marker for prostate cancer |
| US20100086935A1 (en) * | 2001-11-09 | 2010-04-08 | Source Precision Medicine, Inc. | Identification, Monitoring and Treatment of Disease and Characterization of Biological Condition Using Gene Expression Profiles |
| WO2012015765A2 (en) * | 2010-07-27 | 2012-02-02 | Genomic Health, Inc. | Method for using gene expression to determine prognosis of prostate cancer |
| WO2012170715A1 (en) * | 2011-06-07 | 2012-12-13 | Caris Mpi, Inc. | Molecular profiling for cancer |
| US20120329713A1 (en) * | 2008-02-21 | 2012-12-27 | Klem Robert E | Method for determining likelihood of clinical recurrence or clinically stable disease of prostate cancer after radical prostatectomy |
| WO2013116144A1 (en) * | 2012-01-31 | 2013-08-08 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| WO2013184851A1 (en) * | 2012-06-05 | 2013-12-12 | Iris International, Inc. | Method for determining recurrence or stable disease after treatment for prostate cancer |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| GB8822228D0 (en) | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| DE3924454A1 (de) | 1989-07-24 | 1991-02-07 | Cornelis P Prof Dr Hollenberg | Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips) |
| US5252743A (en) | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| ES2097925T3 (es) | 1991-09-18 | 1997-04-16 | Affymax Tech Nv | Metodo para sintetizar diversas colecciones de oligomeros. |
| US5324633A (en) | 1991-11-22 | 1994-06-28 | Affymax Technologies N.V. | Method and apparatus for measuring binding affinity |
| WO1993009668A1 (en) | 1991-11-22 | 1993-05-27 | Affymax Technology N.V. | Combinatorial strategies for polymer synthesis |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| DE69333650T2 (de) | 1992-02-19 | 2006-01-12 | The Public Health Research Institute Of The City Of New York, Inc. | Neue anordnungn von oligonukleotiden und ihr nutzen zum sortieren, isolieren, sequenzieren und manipulieren von nukleinsäuren |
| US5583211A (en) | 1992-10-29 | 1996-12-10 | Beckman Instruments, Inc. | Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides |
| US5491074A (en) | 1993-04-01 | 1996-02-13 | Affymax Technologies Nv | Association peptides |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5472672A (en) | 1993-10-22 | 1995-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for polymer synthesis using arrays |
| US5429807A (en) | 1993-10-28 | 1995-07-04 | Beckman Instruments, Inc. | Method and apparatus for creating biopolymer arrays on a solid support surface |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US6090555A (en) | 1997-12-11 | 2000-07-18 | Affymetrix, Inc. | Scanned image alignment systems and methods |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| WO1995030774A1 (en) | 1994-05-05 | 1995-11-16 | Beckman Instruments, Inc. | Oligonucleotide repeat arrays |
| US5571639A (en) | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
| US5599695A (en) | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
| US5624711A (en) | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5968740A (en) | 1995-07-24 | 1999-10-19 | Affymetrix, Inc. | Method of Identifying a Base in a Nucleic Acid |
| DE69638321D1 (de) | 1995-10-11 | 2011-03-03 | Luminex Corp | Gleichzeitige mehrfachanalyse klinischer proben |
| US5658734A (en) | 1995-10-17 | 1997-08-19 | International Business Machines Corporation | Process for synthesizing chemical compounds |
| US6022963A (en) | 1995-12-15 | 2000-02-08 | Affymetrix, Inc. | Synthesis of oligonucleotide arrays using photocleavable protecting groups |
| EP0902885A4 (en) | 1996-05-16 | 2006-09-27 | Affymetrix Inc | SYSTEMS AND METHODS FOR DETECTION OF BRANDED PRODUCTS |
| US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| ATE234674T1 (de) | 1996-11-14 | 2003-04-15 | Affymetrix Inc | Chemische amplifizierung zur synthese von musterordnungen |
| US6297006B1 (en) | 1997-01-16 | 2001-10-02 | Hyseq, Inc. | Methods for sequencing repetitive sequences and for determining the order of sequence subfragments |
| US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
| US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| WO1999023254A1 (en) | 1997-10-31 | 1999-05-14 | Affymetrix, Inc. | Expression profiles in adult and fetal organs |
| US6087102A (en) | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| US6428752B1 (en) | 1998-05-14 | 2002-08-06 | Affymetrix, Inc. | Cleaning deposit devices that form microarrays and the like |
| US6287776B1 (en) | 1998-02-02 | 2001-09-11 | Signature Bioscience, Inc. | Method for detecting and classifying nucleic acid hybridization |
| WO1999039817A1 (en) | 1998-02-06 | 1999-08-12 | Affymetrix, Inc. | Method of quality control in manufacturing processes |
| JP3944996B2 (ja) | 1998-03-05 | 2007-07-18 | 株式会社日立製作所 | Dnaプローブアレー |
| US6031078A (en) | 1998-06-16 | 2000-02-29 | Millennium Pharmaceuticals, Inc. | MTbx protein and nucleic acid molecules and uses therefor |
| US6277628B1 (en) | 1998-10-02 | 2001-08-21 | Incyte Genomics, Inc. | Linear microarrays |
| US6355431B1 (en) | 1999-04-20 | 2002-03-12 | Illumina, Inc. | Detection of nucleic acid amplification reactions using bead arrays |
| US20030207295A1 (en) | 1999-04-20 | 2003-11-06 | Kevin Gunderson | Detection of nucleic acid reactions on bead arrays |
| ATE413467T1 (de) | 1999-04-20 | 2008-11-15 | Illumina Inc | Detektion von nukleinsäurereaktionen auf kügelchen-arrays |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US6913884B2 (en) | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
| US20040121364A1 (en) | 2000-02-07 | 2004-06-24 | Mark Chee | Multiplex nucleic acid reactions |
| EP1990428B1 (en) | 2000-02-07 | 2010-12-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| JP2001244419A (ja) * | 2000-02-28 | 2001-09-07 | Hitachi Ltd | 高周波モジュール及び移動体検知モジュール |
| US6489606B1 (en) | 2000-04-07 | 2002-12-03 | Cidra Corporation | Bragg grating sensor system with spectral response or code division multiplexing |
| AU8288101A (en) * | 2000-07-07 | 2002-01-21 | Visigen Biotechnologies Inc | Real-time sequence determination |
| US20040018491A1 (en) | 2000-10-26 | 2004-01-29 | Kevin Gunderson | Detection of nucleic acid reactions on bead arrays |
| US8288641B2 (en) * | 2001-12-27 | 2012-10-16 | Intel Corporation | Portable hand-held music synthesizer and networking method and apparatus |
| US20040029151A1 (en) * | 2002-04-09 | 2004-02-12 | Affymetrix, Inc. | Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer |
| US7441703B2 (en) | 2002-08-20 | 2008-10-28 | Illumina, Inc. | Optical reader for diffraction grating-based encoded optical identification elements |
| JP2005536769A (ja) | 2002-08-20 | 2005-12-02 | シヴェラ コーポレイション | 回折格子をベースとする光学同定要素 |
| US20050227252A1 (en) | 2002-08-20 | 2005-10-13 | Moon John A | Diffraction grating-based encoded articles for multiplexed experiments |
| US7164533B2 (en) | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
| WO2004025562A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corp. | Method and apparatus for labelling using diffraction grating-based encoded optical identification elements |
| EP1575707A1 (en) | 2002-09-12 | 2005-09-21 | Cyvera Corporation | Method and apparatus for aligning elongated microbeads in order to interrogate the same |
| US20040259105A1 (en) | 2002-10-03 | 2004-12-23 | Jian-Bing Fan | Multiplex nucleic acid analysis using archived or fixed samples |
| AU2003300368A1 (en) * | 2002-12-26 | 2004-07-29 | Cemines, Llc. | Methods and compositions for the diagnosis, prognosis, and treatment of cancer |
| US20050181394A1 (en) | 2003-06-20 | 2005-08-18 | Illumina, Inc. | Methods and compositions for whole genome amplification and genotyping |
| EP1673614A1 (en) | 2003-10-01 | 2006-06-28 | CiDra Corporation | Optical reader for diffraction grating-based encoded optical identification elements |
| US20060023310A1 (en) | 2004-02-19 | 2006-02-02 | Putnam Martin A | Optical identification element using separate or partially overlapped diffraction gratings |
| US7339165B2 (en) | 2004-07-09 | 2008-03-04 | Hamilton Sundstrand Corporation | Dual outlet pyrolyzer for biological agent detection system |
| AU2005307746B2 (en) | 2004-11-16 | 2011-05-12 | Illumina, Inc. | And methods and apparatus for reading coded microbeads |
| US7914988B1 (en) | 2006-03-31 | 2011-03-29 | Illumina, Inc. | Gene expression profiles to predict relapse of prostate cancer |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| EA201000427A1 (ru) | 2007-10-04 | 2010-10-29 | Хэлсион Молекулар | Секвенирование нуклеиново-кислотных полимеров с использованием электронной микроскопии |
| CA2745961A1 (en) * | 2008-12-04 | 2010-06-10 | The Regents Of The University Of California | Materials and methods for determining diagnosis and prognosis of prostate cancer |
| NZ596468A (en) * | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| TWM395976U (en) * | 2010-06-30 | 2011-01-01 | Tsung-Hung Wu | Electret electroacoustic transducer |
| EP2678448A4 (en) * | 2011-02-22 | 2014-10-01 | Caris Life Sciences Luxembourg Holdings S A R L | CIRCULATING BIOMARKERS |
| WO2014022594A1 (en) | 2012-07-31 | 2014-02-06 | Daniel Mercola | Stroma biomarkers for prostate cancer prognosis |
| US10364469B2 (en) | 2014-01-16 | 2019-07-30 | Illumina, Inc | Gene expression panel for prognosis of prostate cancer recurrence |
-
2015
- 2015-01-16 US US15/111,946 patent/US10364469B2/en active Active
- 2015-01-16 EP EP15701928.2A patent/EP3094747B1/en not_active Not-in-force
- 2015-01-16 WO PCT/US2015/011824 patent/WO2015109234A1/en not_active Ceased
- 2015-01-16 CN CN201580004797.5A patent/CN105917008B/zh active Active
- 2015-01-16 CA CA2935720A patent/CA2935720A1/en active Pending
- 2015-01-16 CN CN202011258642.3A patent/CN112322735A/zh active Pending
- 2015-01-16 JP JP2016565119A patent/JP6666852B2/ja not_active Expired - Fee Related
- 2015-01-16 AU AU2015206336A patent/AU2015206336B2/en not_active Ceased
-
2019
- 2019-07-29 US US16/524,617 patent/US11098372B2/en active Active
-
2020
- 2020-03-26 AU AU2020202145A patent/AU2020202145A1/en not_active Abandoned
-
2021
- 2021-08-18 US US17/405,686 patent/US20220033915A1/en not_active Abandoned
-
2022
- 2022-05-20 AU AU2022203428A patent/AU2022203428A1/en not_active Abandoned
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100086935A1 (en) * | 2001-11-09 | 2010-04-08 | Source Precision Medicine, Inc. | Identification, Monitoring and Treatment of Disease and Characterization of Biological Condition Using Gene Expression Profiles |
| WO2006066965A2 (en) * | 2004-12-24 | 2006-06-29 | Stichting, Katholieke Universiteit, The Universitymedical | Mrna ratios in urinary sediments and/or urine as a prognostic and/or theranostic marker for prostate cancer |
| US20120329713A1 (en) * | 2008-02-21 | 2012-12-27 | Klem Robert E | Method for determining likelihood of clinical recurrence or clinically stable disease of prostate cancer after radical prostatectomy |
| WO2012015765A2 (en) * | 2010-07-27 | 2012-02-02 | Genomic Health, Inc. | Method for using gene expression to determine prognosis of prostate cancer |
| WO2012170715A1 (en) * | 2011-06-07 | 2012-12-13 | Caris Mpi, Inc. | Molecular profiling for cancer |
| WO2013116144A1 (en) * | 2012-01-31 | 2013-08-08 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| WO2013184851A1 (en) * | 2012-06-05 | 2013-12-12 | Iris International, Inc. | Method for determining recurrence or stable disease after treatment for prostate cancer |
Non-Patent Citations (3)
| Title |
|---|
| AHVA SHAHABI ET AL.: "Novel Gene Expression Signature Predictive of Clinical Recurrence After Radical Prostatectomy in Early Stage Prostate Cancer Patients", 《PROSTATE》, vol. 76, no. 14, pages 1239 - 1256 * |
| ATISH D.CHOUDHURY ET AL.: "The role of Genetic Markers in the Management of Prostate Cancer", 《EUROPEAN UROLOGY》, vol. 62, no. 4, pages 5877 - 587 * |
| NONGNUCH NONSRIJUN ET AL.: "Overexpression of Matrix Metalloproteinase 11 in Thai Prostatic Adenocarcinoma is Associated with Poor Survivival", 《ASIAN PACIFIC JOURNAL OF CANCER PREVENTION》, vol. 14, no. 5, pages 3331 - 3335, XP055183507, DOI: 10.7314/APJCP.2013.14.5.3331 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015206336B2 (en) | 2020-01-23 |
| HK1231515A1 (en) | 2017-12-22 |
| US20160333420A1 (en) | 2016-11-17 |
| EP3094747A1 (en) | 2016-11-23 |
| AU2020202145A1 (en) | 2020-04-16 |
| US11098372B2 (en) | 2021-08-24 |
| CN105917008A (zh) | 2016-08-31 |
| WO2015109234A1 (en) | 2015-07-23 |
| AU2022203428A1 (en) | 2022-06-09 |
| CA2935720A1 (en) | 2015-07-23 |
| US20200071770A1 (en) | 2020-03-05 |
| CN105917008B (zh) | 2020-11-27 |
| US10364469B2 (en) | 2019-07-30 |
| US20220033915A1 (en) | 2022-02-03 |
| JP6666852B2 (ja) | 2020-03-18 |
| AU2015206336A1 (en) | 2016-07-14 |
| JP2017503527A (ja) | 2017-02-02 |
| EP3094747B1 (en) | 2018-11-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11098372B2 (en) | Gene expression panel for prognosis of prostate cancer recurrence | |
| JP7042717B2 (ja) | 癌の臨床転帰を予測する方法 | |
| JP6161607B2 (ja) | サンプルにおける異なる異数性の有無を決定する方法 | |
| CN103403543B (zh) | 结肠癌基因表达签名及使用方法 | |
| CN110800063A (zh) | 使用无细胞dna片段大小检测肿瘤相关变体 | |
| JP2007509613A (ja) | 遺伝子発現プロファイリングのためのqRT−PCRアッセイシステム | |
| Clark-Langone et al. | Biomarker discovery for colon cancer using a 761 gene RT-PCR assay | |
| WO2012167112A2 (en) | Gastric cancer biomarkers | |
| JP2024028758A (ja) | 核酸断片間距離情報を用いた染色体異常検出方法 | |
| CN110806480B (zh) | 肿瘤特异性细胞亚群和特征基因及其应用 | |
| HK40047245A (en) | Gene expression panel for prognosis of prostate cancer recurrence | |
| EP4596712A1 (en) | Methods of identifying and using biomarkers | |
| HK1231515B (en) | Gene expression panel for prognosis of prostate cancer recurrence | |
| Smith et al. | Application of DNA-and RNA-based sequencing techniques to tumour tissue samples in the clinical laboratory | |
| WO2025163087A1 (en) | Methods of identifying and using biomarkers | |
| Beaver et al. | Circulating cell-free DNA for molecular diagnostics and therapeutic monitoring | |
| CN121100192A (zh) | 用于鉴定尿液中肾同种异体移植排斥基因的方法和进行这些测量的效用 | |
| CN114250297A (zh) | 基因突变在结肠癌、肺癌易感基因变异检测中的应用 | |
| US20130023427A1 (en) | Methods for assessing genomic instabilities in tumors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40047245 Country of ref document: HK |
|
| AD01 | Patent right deemed abandoned |
Effective date of abandoning: 20250718 |
|
| AD01 | Patent right deemed abandoned |