CN112315890A - 一种美白亮肤组合物及其制备方法和应用 - Google Patents
一种美白亮肤组合物及其制备方法和应用 Download PDFInfo
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- CN112315890A CN112315890A CN202011335273.3A CN202011335273A CN112315890A CN 112315890 A CN112315890 A CN 112315890A CN 202011335273 A CN202011335273 A CN 202011335273A CN 112315890 A CN112315890 A CN 112315890A
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- Prior art keywords
- skin
- whitening
- extract
- brightening
- percent
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- Granted
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- 230000002087 whitening effect Effects 0.000 title claims abstract description 80
- 239000000203 mixture Substances 0.000 title claims abstract description 53
- 238000005282 brightening Methods 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title description 15
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 16
- CLAHOZSYMRNIPY-UHFFFAOYSA-N 2-hydroxyethylurea Chemical compound NC(=O)NCCO CLAHOZSYMRNIPY-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229940031575 hydroxyethyl urea Drugs 0.000 claims abstract description 14
- OGNHOGPWQTWKGQ-VGWMRTNUSA-N (2S)-5-amino-2-[[(2S)-1-[2-[[(2S)-5-amino-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid Chemical compound NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N1[C@H](C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 OGNHOGPWQTWKGQ-VGWMRTNUSA-N 0.000 claims abstract description 13
- 241000907663 Siproeta stelenes Species 0.000 claims abstract description 13
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000008367 deionised water Substances 0.000 claims abstract description 11
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 241001247197 Cephalocarida Species 0.000 claims abstract 3
- 241000736199 Paeonia Species 0.000 claims description 15
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 15
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims description 14
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims description 14
- 229940072008 glycyrrhiza glabra extract Drugs 0.000 claims description 14
- 229940016667 resveratrol Drugs 0.000 claims description 14
- 235000021283 resveratrol Nutrition 0.000 claims description 14
- 239000000463 material Substances 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 10
- 206010040829 Skin discolouration Diseases 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 3
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- 238000000034 method Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 244000236658 Paeonia lactiflora Species 0.000 claims 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 45
- 230000000694 effects Effects 0.000 abstract description 16
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- 231100000344 non-irritating Toxicity 0.000 abstract 1
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- 238000012360 testing method Methods 0.000 description 20
- 230000000052 comparative effect Effects 0.000 description 9
- 241000238582 Artemia Species 0.000 description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 7
- 230000007794 irritation Effects 0.000 description 7
- 230000001815 facial effect Effects 0.000 description 5
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 229940015975 1,2-hexanediol Drugs 0.000 description 3
- 241001672739 Artemia salina Species 0.000 description 3
- 229920000832 Cutin Polymers 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 235000006694 eating habits Nutrition 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 239000000230 xanthan gum Substances 0.000 description 3
- 229920001285 xanthan gum Polymers 0.000 description 3
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- 235000010493 xanthan gum Nutrition 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
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- 230000006872 improvement Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 208000010340 Sleep Deprivation Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 210000003837 chick embryo Anatomy 0.000 description 1
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- 238000005536 corrosion prevention Methods 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000007813 immunodeficiency Effects 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
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- 230000008099 melanin synthesis Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 238000012544 monitoring process Methods 0.000 description 1
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- 230000035945 sensitivity Effects 0.000 description 1
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- 210000004927 skin cell Anatomy 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
Description
测试样品名称 | 得分 | 温和性判定 |
精华液1 | 1.23 | 无刺激 |
精华液2 | 1.56 | 无刺激 |
精华液3 | 1.14 | 无刺激 |
精华液4 | 1.35 | 无刺激 |
精华液5 | 1.26 | 无刺激 |
精华液6 | 1.03 | 无刺激 |
精华液7 | 3.35 | 轻微刺激 |
生理盐水 | 0 | 无刺激 |
Claims (5)
Priority Applications (1)
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CN202011335273.3A CN112315890B (zh) | 2020-11-24 | 2020-11-24 | 一种美白亮肤组合物及其制备方法和应用 |
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CN202011335273.3A CN112315890B (zh) | 2020-11-24 | 2020-11-24 | 一种美白亮肤组合物及其制备方法和应用 |
Publications (2)
Publication Number | Publication Date |
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CN112315890A true CN112315890A (zh) | 2021-02-05 |
CN112315890B CN112315890B (zh) | 2022-10-25 |
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Country Status (1)
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112972360A (zh) * | 2021-03-03 | 2021-06-18 | 上海好肌茵生物科技有限公司 | 一种敏感修复组合物及其制备方法及应用 |
CN113975190A (zh) * | 2021-08-24 | 2022-01-28 | 宁波久瑞生物工程有限公司 | 一种美白组合物及其应用 |
CN115252504A (zh) * | 2022-09-02 | 2022-11-01 | 杭州既见文化有限公司 | 一种舒缓组合物及其应用 |
CN115252504B (zh) * | 2022-09-02 | 2024-06-04 | 杭州既见文化有限公司 | 一种舒缓组合物及其应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080050459A1 (en) * | 2006-08-22 | 2008-02-28 | 3Lab, Inc. | Cosmetic lightening preparation |
CN105326779A (zh) * | 2015-11-24 | 2016-02-17 | 广州市花安堂生物科技有限公司 | 一种舒润莹亮美白啫喱及其制备方法 |
CN106361636A (zh) * | 2016-09-19 | 2017-02-01 | 广东丸美生物技术股份有限公司 | 一种护肤组合物及其在美白亮肤中的应用 |
CN111297788A (zh) * | 2020-04-24 | 2020-06-19 | 广州名门闺秀生物科技有限责任公司 | 一种美白淡斑精华及其制备方法 |
CN111388382A (zh) * | 2019-01-02 | 2020-07-10 | 湖北省吉美化妆品有限公司 | 一种用于美白亮肤的组合物及其在化妆品中的应用 |
CN111956591A (zh) * | 2020-08-25 | 2020-11-20 | 上海新高姿化妆品有限公司 | 一种抗敏舒缓和改善肤色的化妆品组合物及其制备方法 |
-
2020
- 2020-11-24 CN CN202011335273.3A patent/CN112315890B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080050459A1 (en) * | 2006-08-22 | 2008-02-28 | 3Lab, Inc. | Cosmetic lightening preparation |
CN105326779A (zh) * | 2015-11-24 | 2016-02-17 | 广州市花安堂生物科技有限公司 | 一种舒润莹亮美白啫喱及其制备方法 |
CN106361636A (zh) * | 2016-09-19 | 2017-02-01 | 广东丸美生物技术股份有限公司 | 一种护肤组合物及其在美白亮肤中的应用 |
CN111388382A (zh) * | 2019-01-02 | 2020-07-10 | 湖北省吉美化妆品有限公司 | 一种用于美白亮肤的组合物及其在化妆品中的应用 |
CN111297788A (zh) * | 2020-04-24 | 2020-06-19 | 广州名门闺秀生物科技有限责任公司 | 一种美白淡斑精华及其制备方法 |
CN111956591A (zh) * | 2020-08-25 | 2020-11-20 | 上海新高姿化妆品有限公司 | 一种抗敏舒缓和改善肤色的化妆品组合物及其制备方法 |
Non-Patent Citations (1)
Title |
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北京鸣聚力商贸有限责任公司: "《国产普通化妆品备案信息》", 3 February 2020 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112972360A (zh) * | 2021-03-03 | 2021-06-18 | 上海好肌茵生物科技有限公司 | 一种敏感修复组合物及其制备方法及应用 |
CN112972360B (zh) * | 2021-03-03 | 2023-04-07 | 上海好肌茵生物科技有限公司 | 一种敏感修复组合物及其制备方法及应用 |
CN113975190A (zh) * | 2021-08-24 | 2022-01-28 | 宁波久瑞生物工程有限公司 | 一种美白组合物及其应用 |
CN115252504A (zh) * | 2022-09-02 | 2022-11-01 | 杭州既见文化有限公司 | 一种舒缓组合物及其应用 |
CN115252504B (zh) * | 2022-09-02 | 2024-06-04 | 杭州既见文化有限公司 | 一种舒缓组合物及其应用 |
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CN112315890B (zh) | 2022-10-25 |
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Effective date of registration: 20240109 Address after: Room 214, No. 4 Lugang 1st Street, Huadu District, Guangzhou City, Guangdong Province, 510000 (Airport Huadu) Patentee after: Guangzhou Qingmu Cosmetics Co.,Ltd. Address before: 30n, 27th floor, block a, No.3, Shilibao, Chaoyang District, Beijing 100020 Patentee before: Beijing mingjuli Trading Co.,Ltd. |
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Effective date of registration: 20240430 Address after: 100000 30N, 27th Floor, Building A, No. 3 Shilibao A, Chaoyang District, Beijing Patentee after: Beijing mingjuli Trading Co.,Ltd. Country or region after: China Address before: Room 214, No. 4 Lugang 1st Street, Huadu District, Guangzhou City, Guangdong Province, 510000 (Airport Huadu) Patentee before: Guangzhou Qingmu Cosmetics Co.,Ltd. Country or region before: China |