CN112295030A

CN112295030A - Multifunctional dialyzer clamping device and dialyzer

Info

Publication number: CN112295030A
Application number: CN202011335023.XA
Authority: CN
Inventors: 谢华南
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-11-23
Filing date: 2020-11-23
Publication date: 2021-02-02

Abstract

The invention provides a multifunctional dialyzer clamping device and a dialyzer. The dialysis machine is provided with a multifunctional dialyzer clamping device. The multifunctional dialyzer clamping device comprises a base and a chuck, wherein the chuck is connected to the base and used for clamping the dialyzer, and the chuck is connected with a vibrator used for driving the chuck to vibrate. The chuck is connected with the base through a swing mechanism, and the swing mechanism is used for enabling the chuck to swing relative to the base. The vibrator can drive the chuck and the vibration of the dialyzer, and the vibration and the swing of the dialyzer make the heparin continuously injected fully mix with the blood, so that the blood flow keeps a low condensation state, the problems of blood siltation residue and backflow obstruction in hollow fibers of the dialyzer are solved, the blood is ensured to be smooth and sufficient with the blood return in the hollow fibers, the residue of the blood in the hollow fibers is reduced, and the blood loss of patients and the occurrence of anemia complications are reduced.

Description

Multifunctional dialyzer clamping device and dialyzer

Technical Field

The invention relates to medical equipment, in particular to a multifunctional dialyzer clamping device and a dialyzer.

Background

Hemodialysis treatment is one of the major treatment options for uremic patients today. The principle is that the effective components of the dialyzate of the blood inside the hollow fiber of the dialyzer and outside the hollow fiber are exchanged through the wall of the hollow fiber tube (the tube wall is a semipermeable membrane and is provided with a plurality of tiny pores). Thus, toxic human metabolites and excess water in the blood permeate the semipermeable membrane through the action of diffusion ultrafiltration into the dialysate (the electrolyte components and concentration of which are equivalent to those of normal human blood), and are discharged from the body. Each dialyzer consists of a fiber bundle of tens of thousands of hollow fibers and a plastic housing. Blood is led out from the arterial end of the human body, enters the inlet of the dialyzer through a blood pipeline, flows out from the outflow port through the hollow fiber bundle, and returns to the vein of the human body through the blood pipeline, so that a closed loop of extracorporeal circulation is formed. The flow direction of the dialysate is opposite to that of the blood, so that the solute is fully exchanged, and the dialysis treatment effect is improved.

The whole dialysis treatment process is ensured by a special dialysis machine to ensure the safety and the effectiveness of the treatment. The dialyzer is fixed beside the dialysis machine by a supporting clamp. Because the hollow fiber membrane in the dialyzer is foreign matter relative to the human body, the blood coagulation system of the human body is easily activated after the hollow fiber membrane is contacted with blood, and the blood is coagulated in the hollow fiber. Therefore, in the whole treatment process, medicines such as heparin and the like are required to be continuously injected for anticoagulation, so that the phenomenon that some components of blood such as platelets, various blood coagulation factors and fibrin are adsorbed and aggregated on a fiber membrane to form tiny thrombus, large-area blood coagulation seriously occurs, hollow fibers are blocked, the blood flow is blocked, and the dialysis treatment is interrupted is avoided.

Disclosure of Invention

The embodiment of the invention provides a multifunctional dialyzer clamping device and a dialyzer, which can improve the smoothness of blood in hollow fibers and the sufficiency of blood return and reduce the residue of blood in the hollow fibers.

In a first aspect, an embodiment of the present invention provides a multifunctional dialyzer clamping device, which includes a base and a chuck, wherein the chuck is connected to the base, the chuck is used for clamping a dialyzer, and the chuck is connected to a vibrator for driving the chuck to vibrate.

The vibrator is one of a vibration motor, an electromagnetic vibrator and a pneumatic vibrator.

Wherein, be provided with the bumper shock absorber on the chuck, the bumper shock absorber with the pedestal connection.

The shock absorber comprises two shock absorption rubber parts and a sleeve, wherein the two shock absorption rubber parts are sleeved in the sleeve, the two shock absorption rubber parts are in interference fit with the sleeve, a gap is formed between the two shock absorption rubber parts, and the two shock absorption rubber parts are distributed along the axial direction of the sleeve; and the two damping rubber pieces are respectively connected with the chuck and the base.

Wherein the vibrator is disposed at the damper.

A swinging mechanism is connected between the chuck and the base and is used for enabling the chuck to swing relative to the base; the swinging mechanism comprises a swinging driver and a swinging shaft, and the output end of the swinging driver is in transmission connection with the swinging shaft and is used for driving the swinging shaft to perform reciprocating rotation around the self axial direction;

the swing driver is fixed on the base, and the swing shaft is fixedly connected with the chuck; alternatively, the first and second electrodes may be,

the swing driver is fixed on the chuck, and the swing shaft is fixedly connected with the base.

The multifunctional dialyzer clamping device further comprises a control circuit, wherein the control circuit is electrically connected to the vibrator and the swing driver, and the control circuit is used for controlling the working states of the vibrator and the swing driver.

The multifunctional dialyzer clamping device further comprises a rechargeable battery, a charging port and a switch, wherein the rechargeable battery is electrically connected with the vibrator through the switch, and the charging port is electrically connected with the rechargeable battery.

In a second aspect, the invention provides a dialysis machine, wherein the dialysis machine is provided with the multifunctional dialyzer clamping device.

The dialysis machine comprises a control module and a venous line pressure monitoring module, the venous line pressure monitoring module and the vibrator are in communication connection with the control module, and the control module is used for receiving detection data of the venous line pressure monitoring module and controlling the working state of the vibrator according to the detection data.

In the embodiment of the invention, the vibrator for driving the chuck to vibrate is arranged on the chuck, the vibrator can drive the chuck and the dialyzer to vibrate, and the continuously injected heparin is fully mixed with blood through the vibration of the dialyzer, so that the blood flow is kept in a low-condensation state, the problems of blood siltation residue and backflow obstruction in hollow fibers of the dialyzer are solved, the smoothness of the blood in the hollow fibers and the sufficiency of blood return are ensured, the residue of the blood in the hollow fibers is reduced, the blood loss of patients is reduced, the occurrence of anemia complications is reduced, and the smooth proceeding of dialysis treatment is ensured.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Figure 1 is a schematic structural view of a multi-functional dialyzer holding device provided by a preferred embodiment of the present invention;

figure 2 is a schematic structural view of a multi-functional dialyzer holding device provided by another embodiment of the present invention;

figure 3 is a schematic structural view of a multi-functional dialyzer holding device provided by yet another embodiment of the present invention;

figure 4 is a schematic structural view of a multi-functional dialyzer holding device provided by yet another embodiment of the present invention;

figure 5 is a schematic view of the structure of the shock absorber of the multi-functional dialyzer holding device of figure 4.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Furthermore, the following description of the various embodiments refers to the accompanying drawings, which illustrate specific embodiments in which the invention may be practiced. Directional phrases used in this disclosure, such as "long," "left and right," "up and down," and the like, are used in the orientation with reference to the attached drawings only and, thus, are used for better and clearer illustration and understanding of the present invention, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and, therefore, should not be considered limiting of the present invention. Unless expressly stated or limited otherwise, the terms "mounted," "connected," and "coupled" are intended to be inclusive and mean, for example, that they may be fixedly coupled, detachably coupled, or integrally coupled; may be a mechanical connection; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The terms described above are meant to be illustrative in the present invention and are understood to be specific to those of ordinary skill in the art.

The invention provides a dialysis machine and a multifunctional dialyzer clamping device. Hemodialysis reaches and is provided with multi-functional cerini dialyser cerini clamping device, utilizes multi-functional cerini dialyser cerini clamping device can install cerini dialyser cerini detachably in one side of dialysis machine, and the cerini dialyser cerini passes through the pipeline and is connected the back with patient and dialysis machine, alright in order to carry out hemodialysis treatment.

Combine shown in figure 1, multi-functional cerini dialyser cerini clamping device includes base 1 and chuck 2, chuck 2 is connected in base 1, chuck 2 is used for centre gripping cerini dialyser cerini, be provided with on chuck 2 and be used for driving chuck 2 and carry out the vibrator 3 that vibrates, chuck 2 and then can drive the cerini dialyser cerini vibration, the vibration through the cerini dialyser cerini, make the heparin that lasts to inject fully mix with blood, make the blood flow keep the low condensation state, solve the interior blood siltation of cerini dialyser cerini hollow fiber and remain, the obstructed problem of backward flow, guarantee the blood at hollow fiber's the abundant nature of smooth and easy and return blood, can accelerate the dialysis efficiency of hollow fiber inside and outside both sides simultaneously, and then reduce the remaining of blood in hollow fiber, reduce patient.

In the present embodiment, the vibrator 3 is a vibration motor, and in other embodiments, other devices capable of generating vibration, such as an electromagnetic vibrator 3, a pneumatic vibrator 3, and the like, may be used as the vibrator 3. The vibrator 3 may be fixed to the chuck 2, and a vibration output end of the vibrator 3 abuts against the chuck 2, so that the chuck 2 may vibrate.

Chuck 2 is connected with bumper shock absorber 4, and bumper shock absorber 4 is connected with base 1, utilizes bumper shock absorber 4 to be connected chuck 2's main part and base 1, can avoid chuck 2's vibration to transmit to base 1 on to guarantee the stability and the reliability of base 1 department. Here, the damper 4 may be a damper spring, a rubber block, or other devices that can achieve a damping effect.

A swing mechanism 5 is connected between the chuck 2 and the base 1, and the swing mechanism 5 is used for enabling the chuck 2 to swing relative to the base 1, so that the dialyzer can be swung, and the dredging of the blood flowing in the dialyzer is further accelerated.

The swing mechanism 5 comprises a swing driver 51 and a swing shaft 52, wherein the output end of the swing driver 51 is in transmission connection with the swing shaft 52 and is used for driving the swing shaft 52 to perform reciprocating rotation around the self axial direction, and the chuck 2 can swing relative to the base 1 by utilizing the reciprocating rotation of the swing shaft 52.

The swing actuator 51 is fixed to the base 1, and the swing shaft 52 is fixedly connected to the chuck 2, and more specifically, the swing shaft 52 is fixedly connected to the chuck 2 through the damper 4, but in other embodiments, the swing shaft 52 may be directly fixedly connected to the chuck 2, and the damper 4 may be disposed at another position between the chuck 2 and the base 1 or the damper 4 is not disposed. A bearing seat may be provided on the base 1, and the swing shaft 52 is rotatably connected to the bearing seat to ensure the stability of the rotation of the swing shaft 52.

The swing driver 51 may be a mechanism that converts rotational power into reciprocating swing driving force by cooperation of a motor and a four-bar mechanism, a cam mechanism, an intermittent motion mechanism, or the like, or may be an air cylinder, an electromagnetic mechanism, or the like to drive a swing shaft to rotate in a reciprocating manner.

Here, as another embodiment, the swing actuator 51 may be fixed to the chuck 2, and the swing shaft 52 may be fixedly connected to the base 1.

The multifunctional dialyzer clamping device further comprises a control circuit 61, wherein the control circuit 61 is electrically connected to the vibrator 3 and the swing driver 51, and the control circuit 61 is used for controlling the working states of the vibrator 3 and the swing driver 51. For example, the control circuit 61 may control and adjust the operating state of the vibrator 3, such as the vibration frequency, the vibration amplitude, and the vibration intensity, or may control and adjust the operating state of the swing actuator 51, such as the swing amplitude and the frequency, and may adopt different operating states at the beginning, the middle, and the ending of the dialysis treatment, so as to achieve a better effect of dredging the hollow fibers.

Here, the simultaneous control of the vibrator 3 and the swing driver 51 is realized by providing the control circuit 61, but in another embodiment, the vibrator 3 and the swing driver 51 may have a control circuit built therein, respectively, to control the vibrator 3 and the swing driver 51, respectively.

The multifunctional dialyzer clamping device further comprises a rechargeable battery 62, a charging port 63 and a switch 64, wherein the rechargeable battery 62 is arranged inside the clamping head 2, the charging port 63 and the switch 64 are arranged on the outer surface of the clamping head 2, the rechargeable battery 62 is electrically connected with the vibrator 3 and the swing driver 51 through the switch 64, and the charging port 63 is electrically connected with the rechargeable battery 62. The vibrator 3 and the rocking driver 51 can be powered by the rechargeable battery 62, the switch 64 can be used to turn on or off the vibrator 3 and the rocking driver 51, and when a nurse finds that a blockage occurs in the dialyzer or blood is blocked, the switch 64 is turned on to turn on the vibrator 3 and the rocking driver 51, so as to dredge the coagulation of the hollow fibers.

The charging port 63 may be connected to an external power source to charge the rechargeable battery 62, or may directly supply power to the vibrator 3 and the swing driver 51. In other embodiments, the vibrator 3 and the swing driver 51 may be directly connected to an external power source through the switch 64, and the rechargeable battery 62 may not be provided. The vibrator 3 and the swing driver 51 may also be electrically connected to a circuit of the dialysis machine, and directly supplied with power from the dialysis machine, and the operating state thereof may be controlled and adjusted by a control module of the dialysis machine.

The clamping head 2 comprises a first clamping piece 21 and a second clamping piece 22, the first clamping piece 21 is connected with the base 1, one end of the second clamping piece 22 is rotatably connected with the first clamping piece 21, and a clamping cavity 20 for accommodating a dialyzer is formed between the first clamping piece 21 and the second clamping piece 22; the vibrator 3 is disposed in the first holder 21. When the other end of the second clamping member 22 is rotated to a position relatively far away from the second clamping member 22, the dialyzer is placed in the clamping cavity 20 between the first clamping member 21 and the second clamping member 22, and then the other end of the second clamping member 22 is rotated to a position relatively close to the second clamping member 22, so that the dialyzer can be clamped between the first clamping member 21 and the second clamping member 22.

The chamber wall of centre gripping chamber 20 is the arc to make the outer wall of cerini dialyser cerini can laminate mutually with the chamber wall of centre gripping chamber 20, increase the frictional force between cerini dialyser cerini and first holder 21, second holder 22, prevent that the cerini dialyser cerini from droing. The outer surfaces of the first clamping member 21 and the second clamping member 22 may be circular arc-shaped or square-shaped, as shown in fig. 2.

An elastic member is arranged between the first clamping member 21 and the second clamping member 22, the elastic member is used for providing elastic force to enable the second clamping member 22 to rotate towards the first clamping member 21, and the elastic force of the elastic member can enable the dialyzer to be clamped between the first clamping member 21 and the second clamping member 22 more firmly. Here, in other embodiments, a lock may be provided between the other end of the second clamping member 22 and the first clamping member 21, and the other end of the second clamping member 22 may be connected to the first clamping member 21 by the lock to prevent the release.

In order to facilitate the rotation of the second clamping member 22 so that the chuck 2 is opened, a handle 221 is provided on the second clamping member 22.

In this embodiment, the switch 64 is disposed on the first clamping member 21, and the rechargeable battery 62, the control circuit 61, and the charging port 63 are disposed on the second clamping member 22, in other embodiments, as shown in fig. 3, the switch 64, the rechargeable battery 62, the control circuit 61, and the charging port 63 may be disposed on the first clamping member 21, at this time, the structure of the second clamping member 22 may be simplified, so that the second clamping member 22 may be made into a sheet or a plate shape, thereby facilitating the rotation of the second clamping member 22.

In the above embodiment, the clamp 2 clamps and fixes the dialyzer by using the first clamping member 21 and the second clamping member 22 which are rotatably connected, and in other embodiments, the clamp 2 may also fix the dialyzer by using a hoop or other methods. The dialysis clamping device further comprises a clamping mechanism 7, and the clamping mechanism 7 is fixedly connected with the base 1. The clamping mechanism 7 can be used for connecting with other attachments, for example, the clamping mechanism 7 can be used for connecting to some structural members on the side of the dialysis machine, or a sickbed, or other objects such as a supporting column.

In this embodiment, as shown in fig. 1, the clamping mechanism 7 includes a U-shaped fixing member 71 and a bolt 72, the bolt 72 is threaded through one arm of the fixing member 71, the U-shaped fixing member 71 can be sleeved on the outer side of an attachment such as a supporting column, and the supporting column can be clamped in the fixing member 71 by rotating the bolt 72 to abut against the supporting column, so as to achieve the fixed connection between the dialysis clamping device and the attachment. In other embodiments, the clamping mechanism 7 may be connected to the attachment by using other types of structures such as a hoop.

Furthermore, the dialysis machine also comprises a control module and a venous line pressure monitoring module, wherein the venous line pressure monitoring module and the vibrator 3 are in communication connection with the control module, and the control module is used for receiving detection data of the venous line pressure monitoring module and controlling the working state of the vibrator 3 according to the detection data. When the venous line pressure monitoring module monitors that the pressure of the venous line is too high, the condition that an inner pipeline of a dialyzer is not communicated and extravasated blood and the like possibly exists is indicated, and at the moment, the control module can control the vibrator 3 to start working and dredge the pipeline by utilizing vibration.

The swing driver 51 of the swing mechanism 5 is also in communication with the control module, and when the venous line pressure monitoring module monitors that the venous line pressure is too high, the control module can inform the control swing mechanism 5 to start working.

The venous line pressure monitoring module, the vibrator 3 and the swing mechanism 5 are in communication connection with the control module, and can be in wired electric connection or wireless communication connection.

In the above embodiments, the vibrator is disposed on the first clamping member of the chuck, here, in other embodiments, the vibrator may also be disposed on the second clamping member of the chuck, and when the chuck is a hoop or other structure, the vibrator may be disposed on other suitable structure of the chuck as required; when the chuck is connected with the bumper shock absorber, the vibrator also can set up on the bumper shock absorber, because the base is fixed with other attachments, the chuck centre gripping has the dialysis tube to be in unsettled state, and the vibrator setting is on the bumper shock absorber for the vibrator vibration can only be transmitted to on the chuck, thereby makes chuck and dialysis tube vibrate.

The present invention also provides yet another embodiment of a multi-functional dialyzer holding device, which comprises a base 1, a cartridge 2, a vibrator 3, and a rocking mechanism 5, as shown in figure 4.

The clamping head 2 comprises a first clamping piece 21 and a second clamping piece 22, the first clamping piece 21 is connected with the base 1, one end of the second clamping piece 22 is rotatably connected with the first clamping piece 21, and a clamping cavity 20 for accommodating a dialyzer is formed between the first clamping piece 21 and the second clamping piece 22; the vibrator 3 is disposed in the first holder 21. When the other end of the second clamping member 22 is rotated to a position relatively far away from the second clamping member 22, the dialyzer is placed in the clamping cavity 20 between the first clamping member 21 and the second clamping member 22, and then the other end of the second clamping member 22 is rotated to a position relatively close to the second clamping member 22, so that the dialyzer can be clamped between the first clamping member 21 and the second clamping member 22. The vibrator 3 is fixedly connected to a first clamping member 21 of the chuck 1. The multifunctional dialyzer clamping device further comprises a rechargeable battery, a charging port and a switch (not shown in the figure), wherein the rechargeable battery is arranged inside the vibrator 3, the charging port and the switch are arranged on the outer surface of the vibrator 3, the rechargeable battery is electrically connected with the vibrator 3 through the switch, and the charging port is electrically connected with the rechargeable battery. The vibrator 3 can be powered by a rechargeable battery, the switch can be used for starting or closing the vibrator 3, and when a nurse finds that blockage occurs in the dialyzer and blood is blocked, the switch is opened to start the vibrator 3 so as to dredge the blood coagulation of the hollow fibers.

In this embodiment, the vibrator 3 can be operated independently as an independent module by disposing the rechargeable battery, the charging port, and the switch in the vibrator. The vibrator 3 can be connected with the chuck 2 through a detachable structure, and when the electric quantity is insufficient or the fault occurs, the vibrator 3 and the charging related structure can be integrally replaced in time, so that the normal operation of dialysis is ensured. Here, in other embodiments, the power supply module of the dialysis machine may be electrically connected to the vibrator 3 to supply power to the vibrator 3.

The chuck 1 is provided with a damper 4, and the damper 4 is connected with the base 1 through a swing mechanism 5. As shown in fig. 5, the shock absorber 4 includes two shock-absorbing rubber members 41 and a sleeve 42, the two shock-absorbing rubber members 41 are both sleeved in the sleeve 42, the two shock-absorbing rubber members 41 are in interference fit with the sleeve 42, a gap is provided between the shock-absorbing rubber members 41, and the two shock-absorbing rubber members are arranged along the axial direction of the sleeve 42; two damping rubber members 41 are connected to the chuck 2 and the base 1, respectively. Through the damping rubber spare 41 that two intervals set up, can effectively carry out the shock attenuation, avoid on vibration transmits rocking mechanism 5 and base 1. The damping rubber member 41 may be an integral rubber block or may be formed by sleeving a plurality of rubber tubes. The structure of the shock absorber here is equally applicable to the foregoing embodiments.

The swing mechanism 5 comprises a swing driver 51 and a swing shaft 52, wherein the output end of the swing driver 51 is in transmission connection with the swing shaft 52 and is used for driving the swing shaft 52 to perform reciprocating rotation around the self axial direction, and the chuck 2 can swing relative to the base 1 by utilizing the reciprocating rotation of the swing shaft 52. The swing actuator 51 is fixed to the base 1, and the swing shaft 52 is fixedly connected to the chuck 2, and more specifically, the swing shaft 52 is fixedly connected to the chuck 2 through the damper 4. Further, the swing shaft 52 is fixedly connected with one damping rubber member 41, the other damping rubber member 41 is fixedly connected with the chuck 2 through the fixing shaft 43, and the swing shaft 52, the sleeve 42 and the fixing shaft 43 are coaxially arranged to ensure the stability of swing and effectively prevent vibration from being transmitted to the swing shaft 52 and the base.

The dialyzer and the multifunctional dialyzer clamping device provided by the invention can utilize the vibrator 3 and the swing mechanism 5 to enable the dialyzer and the chuck 2 to swing left and right and vibrate, so that heparin continuously injected is fully mixed with blood, the blood flow is kept in a low-condensation state, the blood in the hollow fibers of the dialyzer can quickly and effectively flow through the hollow fibers, the resistance of the blood flow is reduced, the adsorption and aggregation of platelets on the wall of the hollow limiting membrane are reduced, the formation of thrombus and blood coagulation is prevented, and the residue of the blood in the hollow fibers is reduced.

The dialysis machine and the multifunctional dialyzer clamping device provided by the invention have the functions of shaking and vibrating, and can regularly and quantitatively (such as the amplitude, intensity and frequency of shaking and vibrating) shake and vibrate by utilizing the control circuit and the hemodialysis and control module in the dialysis process of a patient and the blood return process after treatment is finished, so that the smoothness of blood in the hollow fibers and the sufficiency of blood return are ensured to the maximum extent, the residue of blood in the hollow fibers is reduced, the blood loss of the patient is reduced, and the occurrence of anemia complications is reduced. The multifunctional dialyzer clamping device can keep the effective vibration of the chuck and prevent the vibration from being conducted to the fixed seat, so that damage and larger noise of the dialyzer are avoided.

While the invention has been described with reference to specific embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims

1. The utility model provides a multi-functional cerini dialyser cerini clamping device which characterized in that, includes base and chuck, the chuck connect in the base, the chuck is used for the centre gripping cerini dialyser cerini, the chuck is connected with and is used for driving the chuck carries out the vibrator that vibrates.

2. The multi-functional dialyzer clamping device of claim 1 wherein the vibrator is one of a vibrating motor, an electromagnetic vibrator, and a pneumatic vibrator.

3. The multi-functional dialyzer clamping device of claim 1 wherein a shock absorber is disposed on the clamp head, the shock absorber being connected to the base.

4. The multifunctional dialyzer clamping device of claim 3, wherein the damper comprises two damping rubber members and a sleeve, the two damping rubber members are sleeved in the sleeve, the two damping rubber members are in interference fit with the sleeve, a gap is arranged between the two damping rubber members, and the two damping rubber members are arranged along the axial direction of the sleeve; and the two damping rubber pieces are respectively connected with the chuck and the base.

5. The multi-functional dialyzer clamping device of claim 3, wherein the vibrator is disposed at the shock absorber.

6. The multi-functional dialyzer clamping device of any one of claims 1 to 5 wherein a rocking mechanism is connected between the cartridge and the base for rocking movement of the cartridge relative to the base; the swinging mechanism comprises a swinging driver and a swinging shaft, and the output end of the swinging driver is in transmission connection with the swinging shaft and is used for driving the swinging shaft to perform reciprocating rotation around the self axial direction;

7. The multi-functional dialyzer clamping device of claim 6 further comprising a control circuit electrically connected to the vibrator and the rocking driver, the control circuit for controlling the operating state of the vibrator and the rocking driver.

8. The multi-functional dialyzer clamping device of claim 1 further comprising a rechargeable battery electrically connected to the vibrator via a switch, a charging port electrically connected to the rechargeable battery, and a switch.

9. Dialysis machine, characterized in that, the dialysis machine is provided with the multifunctional dialyzer clamping device of any one of claims 1 to 8.

10. The dialysis machine of claim 9, comprising a control module and a venous line pressure monitoring module, wherein the venous line pressure monitoring module and the vibrator are communicatively connected to the control module, and the control module is configured to receive detection data from the venous line pressure monitoring module and control an operating state of the vibrator according to the detection data.