CN112274445A - Gingiva protecting mouthwash containing arginine and preparation method thereof - Google Patents
Gingiva protecting mouthwash containing arginine and preparation method thereof Download PDFInfo
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- CN112274445A CN112274445A CN202011522630.7A CN202011522630A CN112274445A CN 112274445 A CN112274445 A CN 112274445A CN 202011522630 A CN202011522630 A CN 202011522630A CN 112274445 A CN112274445 A CN 112274445A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The invention discloses a gingiva protecting mouthwash containing arginine and a preparation method thereof, wherein the gingiva protecting mouthwash is prepared from the following raw materials in parts by weight: 4-10 parts of arginine, 0.1-0.2 part of lysozyme, 0.2-0.5 part of vitamin C, 0.1-0.2 part of flavoring agent, 2-5 parts of transglutaminase, 1-3 parts of trimethylglycine and 80-95 parts of pure water, and adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer to be uniformly stirred; heating to 60-80 deg.C while stirring, and stirring for 10-20 min; then adding flavoring agent, keeping the temperature at 30-40 deg.C, stirring for 5-10 min, taking out, bottling, and sealing to obtain the final product. The mouthwash prepared by the invention has high safety, small irritation and mild taste.
Description
Technical Field
The invention relates to a mouthwash, in particular to a gingiva protecting mouthwash containing arginine and a preparation method thereof.
Background
In order to solve the simple problem of halitosis, people use various methods, such as brushing teeth, chewing gum, eating tea, and the like. These methods are not ideal and inconvenient although they can achieve a certain effect. With the improvement of living standard and the continuous pursuit of beauty, oral hygiene and oral health become one of the focuses of modern people. The oral hygiene care is not limited to brushing twice in the morning and at night, and carrying the mouthwash with the mouth is fashionable, and the mouth wash plays an increasingly important role in daily life. The mouthwash is a novel product in the scientific and technological era, and can be used for treating oral diseases and throat diseases by matching various medicinal components, and can also eliminate halitosis caused by mouth diseases, abnormal food eating, poor sleep, mental stress, dyspepsia and the like while treating the oral diseases.
Daily oral health care is important for the prevention and control of plaque-related oral diseases (caries, gingivitis, periodontal disease). Inhibiting the formation of plaque or killing bacteria in plaque is another effective way to control plaque using effective chemicals. When the oil is used for gargling, the oil has high adhesiveness, is easier to fill oral teeth, gums and mucous membranes than water, has lipophilicity, is easier to melt bacteria in the oil than the water, is absorbed by the tongue, quickly brings nutrition of the oil into blood, and discharges bacteria and toxins in the blood into the oil. Oil mouth rinsing provides a good method to improve the health of the oral cavity and the body system.
The existing mouthwash has only simple gargling function and no other additional function, and is difficult to meet the higher and higher use requirements of people.
Disclosure of Invention
In order to solve the technical problems, the invention provides the gingiva-protecting mouthwash containing arginine and the preparation method thereof.
In order to solve the technical problems, the invention adopts the following technical scheme:
the gingiva protecting mouthwash containing arginine is prepared from the following raw materials in parts by weight:
4-10 parts of arginine, 0.1-0.2 part of lysozyme, 0.2-0.5 part of vitamin C, 0.1-0.2 part of flavoring agent, 2-5 parts of transglutaminase, 1-3 parts of trimethylglycine and 80-95 parts of pure water.
The flavoring agent is one or more of sorbitol, stevioside and menthol
The composite material consists of the following raw materials in parts by weight:
7 parts of arginine, 0.15 part of lysozyme, 0.25 part of vitamin C, 0.15 part of flavoring agent, 3 parts of transglutaminase, 2 parts of trimethylglycine and 90 parts of pure water.
A preparation method of a mouth wash containing arginine for protecting gum is characterized by comprising the following steps:
adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer and stirring uniformly;
heating to 60-80 deg.C while stirring, and stirring for 10-20 min;
then adding flavoring agent, keeping the temperature at 30-40 deg.C, stirring for 5-10 min, taking out, bottling, and sealing to obtain the final product.
The stirring speed is 150-300 r/min.
The temperature is heated to 60-80 ℃ at a rate of 4-6 ℃/min.
When the temperature is reduced from 60-80 ℃, the temperature is cooled to 30-40 ℃ according to the speed of 3-5 ℃/min.
The toothpaste has the function of protecting the gum, is mild in taste, has a bacteriostatic effect, and can play a role in bacteriostasis, whitening teeth, fixing teeth, comprehensively nursing the oral cavity and keeping teeth healthy.
Detailed Description
The present invention will be described in further detail with reference to specific embodiments in order to further understand the features and technical means of the invention and achieve specific objects and functions.
Example one
The gingiva protecting mouthwash containing arginine is prepared from the following raw materials in parts by weight:
4 parts of arginine, 0.1 part of lysozyme, 0.2 part of vitamin C, 0.1 part of flavoring agent, 2 parts of transglutaminase, 1 part of trimethylglycine and 95 parts of pure water. The flavoring agent is sorbitol.
A preparation method of a mouth wash containing arginine for protecting gum is characterized by comprising the following steps:
adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer, and stirring uniformly.
During the stirring process, the temperature is heated to 60 ℃ and stirred for 10 minutes at the stirring speed of 150 r/min. During the temperature rise, the mixture was heated to 60 ℃ at a rate of 4 ℃ per minute.
Then adding flavoring agent, keeping the temperature at 30 deg.C, stirring for 10 min, taking out, bottling, and sealing to obtain the final product. During the process of reducing the temperature from 60 ℃ to 30 ℃, the temperature is cooled to 30 ℃ according to the speed of 3 ℃/min.
Example two
The gingiva protecting mouthwash containing arginine is prepared from the following raw materials in parts by weight:
7 parts of arginine, 0.15 part of lysozyme, 0.25 part of vitamin C, 0.15 part of flavoring agent, 3 parts of transglutaminase, 2 parts of trimethylglycine and 90 parts of pure water. The flavoring agent is menthol.
A preparation method of a mouth wash containing arginine for protecting gum is characterized by comprising the following steps:
adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer, and stirring uniformly.
During the stirring process, the temperature is heated to 70 ℃ and stirred for 15 minutes at the stirring speed of 200 r/min. During the temperature rise, the mixture was heated to 70 ℃ at a rate of 5 ℃ per minute.
Then adding flavoring agent, keeping temperature at 35 deg.C, stirring for 7 min, taking out, bottling, and sealing to obtain the final product. During the cooling from 70 ℃ to 35 ℃, the temperature is cooled to 35 ℃ at a rate of 4 ℃/min.
EXAMPLE III
The gingiva protecting mouthwash containing arginine is prepared from the following raw materials in parts by weight:
10 parts of arginine, 0.2 part of lysozyme, 0.5 part of vitamin C, 0.2 part of flavoring agent, 5 parts of transglutaminase, 3 parts of trimethylglycine and 80 parts of pure water. The flavoring agent is menthol.
A preparation method of a mouth wash containing arginine for protecting gum is characterized by comprising the following steps:
adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer, and stirring uniformly.
During the stirring process, the temperature is heated to 80 ℃ and stirred for 20 minutes at the stirring speed of 300 r/min. During the temperature rise, the mixture was heated to 80 ℃ at a rate of 6 ℃ per minute.
Then adding flavoring agent, keeping the temperature at 40 deg.C, stirring for 5 min, taking out, bottling, and sealing to obtain the final product. During the cooling from 80 ℃ to 40 ℃, the temperature is cooled to 40 ℃ according to the speed of 3 ℃/min.
Although the present invention has been described in detail with reference to the embodiments, it will be apparent to those skilled in the art that modifications, equivalents, improvements, and the like can be made in the technical solutions of the foregoing embodiments or in some of the technical features of the foregoing embodiments, but those modifications, equivalents, improvements, and the like are all within the spirit and principle of the present invention.
Claims (7)
1. The gingiva-protecting mouthwash containing arginine is characterized by consisting of the following raw materials in parts by weight:
4-10 parts of arginine, 0.1-0.2 part of lysozyme, 0.2-0.5 part of vitamin C, 0.1-0.2 part of flavoring agent, 2-5 parts of transglutaminase, 1-3 parts of trimethylglycine and 80-95 parts of pure water.
2. The gingiva-protecting mouthwash containing arginine according to claim 1, wherein the flavoring agent is one or more combinations of sorbitol, steviol glycosides and menthol.
3. The gingiva-protecting mouthwash containing arginine according to claim 2, which is prepared from the following raw materials in parts by weight:
7 parts of arginine, 0.15 part of lysozyme, 0.25 part of vitamin C, 0.15 part of flavoring agent, 3 parts of transglutaminase, 2 parts of trimethylglycine and 90 parts of pure water.
4. A method of preparing the arginine-containing gum mouth rinse of any one of claims 1-3, comprising the steps of:
adding arginine, lysozyme, vitamin C, transglutaminase, trimethylglycine and pure water into a stirrer and stirring uniformly;
heating to 60-80 deg.C while stirring, and stirring for 10-20 min;
then adding flavoring agent, keeping the temperature at 30-40 deg.C, stirring for 5-10 min, taking out, bottling, and sealing to obtain the final product.
5. The method for preparing the gingiva-protecting mouthwash containing arginine according to claim 4, wherein the stirring speed is 150-300 r/min.
6. The method of preparing the gingiva-protecting mouthwash containing arginine of claim 5, wherein the temperature is heated to 60-80 ℃ at a rate of 4-6 ℃/minute.
7. The method for preparing the gingiva-protecting mouth wash containing arginine according to claim 6, wherein the temperature is reduced from 60-80 ℃ and then cooled to 30-40 ℃ at a rate of 3-5 ℃/min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011522630.7A CN112274445A (en) | 2020-12-21 | 2020-12-21 | Gingiva protecting mouthwash containing arginine and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011522630.7A CN112274445A (en) | 2020-12-21 | 2020-12-21 | Gingiva protecting mouthwash containing arginine and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN112274445A true CN112274445A (en) | 2021-01-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011522630.7A Pending CN112274445A (en) | 2020-12-21 | 2020-12-21 | Gingiva protecting mouthwash containing arginine and preparation method thereof |
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| Country | Link |
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| CN (1) | CN112274445A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102342896A (en) * | 2011-10-08 | 2012-02-08 | 哈尔滨恩瑞科技发展有限公司 | Biological enzyme mouthwash |
| CN103974691A (en) * | 2011-12-15 | 2014-08-06 | 高露洁-棕榄公司 | Aqueous oral care compositions |
| CN106726684A (en) * | 2016-12-28 | 2017-05-31 | 安徽紫檀科技有限公司 | A kind of refrigerant mouthwash, preparation method and applications |
| CN109172475A (en) * | 2018-11-26 | 2019-01-11 | 上海怡竹生物科技有限公司 | A kind of antibacterial whitening mouthwash and preparation method thereof |
-
2020
- 2020-12-21 CN CN202011522630.7A patent/CN112274445A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102342896A (en) * | 2011-10-08 | 2012-02-08 | 哈尔滨恩瑞科技发展有限公司 | Biological enzyme mouthwash |
| CN103974691A (en) * | 2011-12-15 | 2014-08-06 | 高露洁-棕榄公司 | Aqueous oral care compositions |
| CN106726684A (en) * | 2016-12-28 | 2017-05-31 | 安徽紫檀科技有限公司 | A kind of refrigerant mouthwash, preparation method and applications |
| CN109172475A (en) * | 2018-11-26 | 2019-01-11 | 上海怡竹生物科技有限公司 | A kind of antibacterial whitening mouthwash and preparation method thereof |
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Application publication date: 20210129 |
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| RJ01 | Rejection of invention patent application after publication |