CN112237680A - Axial-flow type heart auxiliary device with heparin coating and hydrophobic protection - Google Patents
Axial-flow type heart auxiliary device with heparin coating and hydrophobic protection Download PDFInfo
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- CN112237680A CN112237680A CN202010968939.2A CN202010968939A CN112237680A CN 112237680 A CN112237680 A CN 112237680A CN 202010968939 A CN202010968939 A CN 202010968939A CN 112237680 A CN112237680 A CN 112237680A
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- blood
- driving motor
- heparin
- axial
- stator shell
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- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 229960002897 heparin Drugs 0.000 title claims abstract description 26
- 229920000669 heparin Polymers 0.000 title claims abstract description 26
- 230000002209 hydrophobic effect Effects 0.000 title claims abstract description 24
- 238000000576 coating method Methods 0.000 title claims abstract description 12
- 239000011248 coating agent Substances 0.000 title claims abstract description 11
- 239000008280 blood Substances 0.000 claims abstract description 42
- 210000004369 blood Anatomy 0.000 claims abstract description 39
- 230000017531 blood circulation Effects 0.000 claims abstract description 16
- 239000000463 material Substances 0.000 claims abstract description 11
- 230000000747 cardiac effect Effects 0.000 claims description 3
- 208000007536 Thrombosis Diseases 0.000 abstract description 5
- 230000015572 biosynthetic process Effects 0.000 abstract description 4
- 238000011010 flushing procedure Methods 0.000 description 7
- 210000000709 aorta Anatomy 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 210000005240 left ventricle Anatomy 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 230000004217 heart function Effects 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 208000005189 Embolism Diseases 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 238000000707 layer-by-layer assembly Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010024119 Left ventricular failure Diseases 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- QJVKUMXDEUEQLH-UHFFFAOYSA-N [B].[Fe].[Nd] Chemical compound [B].[Fe].[Nd] QJVKUMXDEUEQLH-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000002473 artificial blood Substances 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000005242 cardiac chamber Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920000867 polyelectrolyte Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003938 response to stress Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
- A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
- A61M60/416—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/818—Bearings
- A61M60/825—Contact bearings, e.g. ball-and-cup or pivot bearings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/857—Implantable blood tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Mechanical Engineering (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention belongs to the technical field of medical instruments, and particularly relates to an axial-flow type heart auxiliary device with a heparin coating and hydrophobic protection, which comprises a blood flow channel, an axial-flow impeller and a driving motor, wherein the driving motor comprises a stator shell which is integrally cylindrical, the stator shell is provided with an accommodating space for arranging a cylindrical rotor, two ends of the cylindrical rotor are provided with rotating shafts, bearings are arranged between shaft bodies at two ends of the rotating shafts and two ends of the stator shell, and heparin is attached to the surfaces of the stator shell and the cylindrical rotor; through all having attached to heparin on stator housing and the adjacent surface of column rotor, the effectual formation that restraines the thrombus is all attached to hydrophobic material on the internal surface of the bearing that closes on the blood outflow simultaneously to and the axle body that corresponds the pivot, the effectual inside that blocks blood and enter into driving motor.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to an axial-flow type heart assist device with a heparin coating and hydrophobic protection.
Background
For left heart failure patients, in case of ineffective medication, it is often necessary to provide a left heart assist device for purposes including: 1) waiting for the donor, preparing for heart transplantation; 2) the heart can be rested and the heart function can be recovered. The current left heart auxiliary device mainly comprises a temporary left heart auxiliary device and a long-term left heart auxiliary device; the temporary left heart auxiliary device comprises a partial axial flow pump and an air bag pulsating device and is mainly characterized by percutaneous puncture or incision and transvascular implantation; the advantages that the device can be implanted quickly, is relatively simple to drive, and is suitable for emergency rescue conditions of sudden cardiac failure; however, temporary left heart assist devices are not suitable for long term assistance, are placed in the neck or groin area, are only suitable for bedridden patients, require sedation during use, and are susceptible to infection at the transvascular delivery site. The long-term left heart auxiliary device comprises a pneumatic pump, a centrifugal pump and a partial axial flow pump, and is mainly characterized in that the device is placed in the chest by opening, a hole is formed in the apex of the left ventricle, the left ventricle blood is drained to enter the long-term left heart auxiliary device, and the pressurized blood is pumped into the aorta through an artificial blood vessel; the advantage lies in that the consumptive material is changed easily, and drive arrangement design is simple, but the shortcoming is also very obvious, and drive arrangement is comparatively huge, is unsuitable to be arranged in vivo, and exposes to the external pump body and the visual pump blood activity, causes harmful effects easily to patient's psychology to and, need pipe connection heart chamber and aorta, increased the energy consumption, and easily form the thrombus.
In the prior art, Impella is a commonly used temporary left heart assist device, which comprises a pigtail, a blood inflow port, a blood flow channel, a blood outflow port, an axial flow impeller, a driving motor and other components, wherein in the specific working process, the driving motor drives the axial flow impeller to rotate, so that blood is pumped from a left ventricle to an aorta, and the blood circulation of a patient is assisted. There is a bearing seal above the shaft of the driving motor, the purpose of the bearing seal is to prevent that when the axial impeller draws blood out, blood can enter the inside of the driving motor through the air gap of the bearing, thereby cause the short circuit of the driving motor and cause a series of bad accidents, and the existence of the bearing seal blocks the blood from flowing into the inside of the driving motor, but the blood ceaselessly strikes the bearing seal, thereby the blood cells receive huge impact force and produce stress response, secrete platelets, therefore the blood cells on the surface of the bearing can be gradually coagulated, finally form embolism, in case the embolism drops and enters the blood vessel and can block up direct less blood vessel, seriously affect the life safety of patients. Aiming at the problem, the scheme adopted by Impella is to add a shaft seal flushing system, namely, a plurality of holes of 0.9mm are arranged at the shaft seal position of a driving motor, a physiological saline supply device is externally connected with a pipeline to continuously flush the shaft seal position, the flushing amount is 240mL every 24 hours, and the pressure at the flushing position is up to 600 mmHg. The shaft seal flushing system described above presents significant drawbacks: firstly, the manufacturing difficulty of the driving motor is increased, the shaft seal flushing hole needs to be connected to external equipment through a pipeline to complete the flushing function, so that the hole needs to be punched through the driving motor, and the diameter of the hole is only 0.9mm, which brings great challenges to the processing and manufacturing of the driving motor; the other is that the shaft seal flushing system is equivalent to the continuous liquid injection into the blood circulation system of the patient, which increases the circulation flow and the afterload of the heart, which is extremely unfavorable for the recovery of the heart function of the heart failure patient.
Disclosure of Invention
In view of the problems in the prior art, the invention aims to provide an axial-flow type heart assist device with a heparin coating and a hydrophobic protection, which effectively prevents blood from coagulating at a motor shaft seal and ensures the stability of the operation of Impella.
In order to achieve the purpose, the invention adopts the following technical scheme:
an axial flow cardiac assist device with heparin coating and hydrophobic protection, comprising:
a blood flow channel having a blood inflow port and a blood outflow port;
the axial flow impeller is rotationally connected inside the blood flow channel; and
the driving motor is positioned outside the blood outflow port and used for driving the axial flow impeller to rotate and propelling the blood in the blood flow channel to flow;
the driving motor comprises a cylindrical stator shell, the stator shell is provided with an accommodating space for arranging the columnar rotor, rotating shafts are arranged at two ends of the columnar rotor, bearings are arranged between shaft bodies at two ends of the rotating shafts and two ends of the stator shell, and heparin is attached to the surfaces of the stator shell and the columnar rotor.
Preferably, the inner surface of the bearing of the driving motor adjacent to the blood outflow port and the shaft body corresponding to the rotation shaft are attached with hydrophobic materials.
Compared with the prior art, the invention has the following technical effects:
according to the axial-flow type heart auxiliary device provided by the invention, heparin is adhered to the surfaces of the stator shell and the columnar rotor which are adjacent to each other, so that the formation of thrombus is effectively inhibited, and meanwhile, hydrophobic materials are adhered to the inner surface of the bearing close to the blood outflow port and the shaft body corresponding to the rotating shaft, so that the blood is effectively prevented from entering the driving motor;
compared with the prior art, the axial-flow type heart auxiliary device provided by the invention can not damage blood, and avoids the increase of blood circulation flow and afterload increase, and has side effect on the recovery of cardiac function of a patient; in addition, the invention avoids the traditional scheme that holes are formed in the motor body, namely the design and processing difficulty of the motor is reduced, and simultaneously, a normal saline water supply system of a left-heart auxiliary system is abandoned, so that the device is simpler.
Additional features and advantages of the invention will be set forth in the detailed description which follows.
Drawings
Fig. 1 is a schematic structural diagram of an axial flow type heart assist device with a heparin coating and hydrophobic protection according to an embodiment of the invention;
fig. 2 illustrates a sectional view of a driving motor provided according to an embodiment of the present invention;
the reference numbers in the figures illustrate: 10-blood flow channel, 11-blood inflow port, 12-blood outflow port, 20-driving motor, 21-stator shell, 22-columnar rotor, 23-rotating shaft and 24-bearing.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further clarified by combining the specific drawings.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in fig. 1 and 2, the present invention provides an axial flow type heart assist device with heparin coating and hydrophobic protection, which includes a blood flow channel 10, an axial flow impeller (not shown in the figure) and a driving motor 20;
the blood flow channel 10 is provided with a blood inlet 11 and a blood outlet 12, the axial flow impeller is rotatably connected inside the blood flow channel 10, and the driving motor is located outside the blood outlet 12 and used for driving the axial flow impeller to rotate and impel the blood in the blood flow channel 10 to flow;
the driving motor 20 includes a stator housing 21 integrally formed in a cylindrical shape, the stator housing 21 has an accommodating space for arranging a cylindrical rotor 22, rotating shafts 23 are provided at two ends of the cylindrical rotor 22, bearings 24 are provided between shaft bodies at two ends of the rotating shafts 23 and two ends of the stator housing 21, and heparin is attached to surfaces of the stator housing 21 and the cylindrical rotor 22.
In the invention, the stator shell 21 and the columnar rotor 22 of the driving motor 20 are manufactured separately, and after the stator shell 21 is processed, the stator shell is soaked in heparin liquid by a chemical soaking method, so that a layer of heparin is adhered to the inner surface of the stator shell; the same method is used for the columnar rotor 22, so that a layer of heparin is attached to the surface of the columnar rotor 22; in specific use, because heparin is adhered to the surfaces of the stator housing 21 adjacent to the columnar rotor 22, blood coagulation can be effectively prevented.
Specifically, as a specific embodiment of the present invention, the stator housing 21 is made of polyurethane, the columnar rotor 22 is made of neodymium iron boron, the stator housing 21 and the columnar rotor 22 are immersed in 85% heparin aqueous solution, and the ultra-thin heparin film is formed on the surface by using an electrostatic self-assembly method and using a supermolecular electrostatic self-assembly principle to adsorb polyelectrolytes with opposite charges at a time under the action of electrostatic attraction. During the operation of the device, heparin can be continuously released to play an anticoagulation role, and the time can reach 7-14 days.
Further, according to the present invention, the inner surface of the bearing 24 of the driving motor 20 adjacent to the blood outflow port 12 and the shaft body corresponding to the rotation shaft 23 are attached with hydrophobic materials. In a specific embodiment, a hydrophobic material is electrochemically grafted on the inner surface of the bearing 24 of the driving motor 20 adjacent to the blood outflow port 12, and a hydrophobic material is grafted on the shaft body surface of the rotary shaft 23 in the same manner, so that the gap between the bearing 24 and the rotary shaft 23 is almost filled with the hydrophobic material having the same hydrophobic property as the substance on the surface of lotus leaves, and the stay of the liquid can be prevented, and even if a small amount of blood enters the air gap of the driving motor 20 through the hydrophobic surface, i.e., the area between the stator housing 21 and the cylindrical rotor 22, the heparin attached to the surface of the stator housing 21 adjacent to the cylindrical rotor 22 can effectively prevent the formation of thrombus.
Specifically, in one embodiment of the present invention, the hydrophobic material uses Sysmyk (SYSMEK GMBH AG & co., LTD, uk) commercially available hydrophobic coatings that have good hydrophobic properties; after the bearing 24 and the rotating shaft 23 are manufactured, the surfaces of the bearing and the rotating shaft are treated to remove dirt on the surfaces, and the requirements of no rust, no oil dirt, no dust and no water mark are met; spraying Sysmyk in clean environment after cleaning, and curing at normal temperature or baking at low temperature.
When the axial-flow type heart auxiliary device with the heparin coating and the hydrophobic protection is used specifically, the axial-flow type heart auxiliary device is implanted through a femoral artery of a human body in a minimally invasive mode, ascends and crosses an aortic arch, finally a blood inflow port enters a left ventricle, a blood outflow port is located in an aorta, and when a driving motor works, blood deposited in the left ventricle is pumped out and pumped into the aorta; based on the scheme provided by the invention, heparin is adhered to the surfaces of the stator shell 21 adjacent to the columnar rotor 22, so that the formation of thrombus is effectively inhibited, and meanwhile, hydrophobic materials are adhered to the inner surface of the bearing 24 close to the blood outflow port 12 and the shaft body corresponding to the rotating shaft 23, so that the blood is effectively prevented from entering the interior of the driving motor 20.
Compared with the prior art, the technical scheme provided by the invention has the advantages that the blood cannot be damaged, the increase of blood circulation flow and the rise of afterload are avoided, and the side effect on the recovery of the cardiac function of a patient is avoided; in addition, the invention avoids the traditional scheme that holes are formed in the motor body, namely the design and processing difficulty of the motor is reduced, and simultaneously, a normal saline water supply system of a left-heart auxiliary system is abandoned, so that the device is simpler.
The foregoing shows and describes the general principles, essential features, and inventive features of this invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (2)
1. An axial flow cardiac assist device with heparin coating and hydrophobic protection, comprising:
a blood flow channel having a blood inflow port and a blood outflow port;
the axial flow impeller is rotationally connected inside the blood flow channel; and
the driving motor is positioned outside the blood outflow port and used for driving the axial flow impeller to rotate and propelling the blood in the blood flow channel to flow;
the driving motor comprises a cylindrical stator shell, the stator shell is provided with an accommodating space for arranging the columnar rotor, rotating shafts are arranged at two ends of the columnar rotor, bearings are arranged between shaft bodies at two ends of the rotating shafts and two ends of the stator shell, and heparin is attached to the surfaces of the stator shell and the columnar rotor.
2. The axial flow cardiac assist device with heparin coating and hydrophobic protection as claimed in claim 1, wherein the inner surface of the bearing of the driving motor adjacent to the blood outflow port and the shaft of the corresponding rotating shaft are attached with hydrophobic material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010968939.2A CN112237680B (en) | 2020-09-15 | 2020-09-15 | Axial-flow heart auxiliary device with heparin coating and hydrophobic protection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010968939.2A CN112237680B (en) | 2020-09-15 | 2020-09-15 | Axial-flow heart auxiliary device with heparin coating and hydrophobic protection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112237680A true CN112237680A (en) | 2021-01-19 |
| CN112237680B CN112237680B (en) | 2023-08-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010968939.2A Active CN112237680B (en) | 2020-09-15 | 2020-09-15 | Axial-flow heart auxiliary device with heparin coating and hydrophobic protection |
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| Country | Link |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115227964A (en) * | 2022-09-21 | 2022-10-25 | 深圳核心医疗科技有限公司 | Flow velocity control method and device |
| WO2023226779A1 (en) * | 2022-05-24 | 2023-11-30 | 苏州心岭迈德医疗科技有限公司 | Catheter interventional heart pump |
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|---|---|---|---|---|
| JPH06218043A (en) * | 1993-01-27 | 1994-08-09 | Nikkiso Co Ltd | Blood pump |
| JPH06312457A (en) * | 1993-04-30 | 1994-11-08 | Ntn Corp | Formation of corrosion-resistant fluoroplastic membrane coating |
| JP2004190562A (en) * | 2002-12-11 | 2004-07-08 | Matsushita Electric Ind Co Ltd | Small vortex pump |
| JP2006218010A (en) * | 2005-02-09 | 2006-08-24 | Hideo Hoshi | Blood pump and dynamic pressure bearing |
| CN104632893A (en) * | 2014-12-25 | 2015-05-20 | 江南大学 | Porous hydrostatic pressure bearing structure based on hydrophobic interfaces |
| WO2018210370A1 (en) * | 2017-05-17 | 2018-11-22 | Schaeffler Technologies AG & Co. KG | Wheel-hub rolling element bearing assembly having a hydrophobic coating |
-
2020
- 2020-09-15 CN CN202010968939.2A patent/CN112237680B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06218043A (en) * | 1993-01-27 | 1994-08-09 | Nikkiso Co Ltd | Blood pump |
| JPH06312457A (en) * | 1993-04-30 | 1994-11-08 | Ntn Corp | Formation of corrosion-resistant fluoroplastic membrane coating |
| JP2004190562A (en) * | 2002-12-11 | 2004-07-08 | Matsushita Electric Ind Co Ltd | Small vortex pump |
| JP2006218010A (en) * | 2005-02-09 | 2006-08-24 | Hideo Hoshi | Blood pump and dynamic pressure bearing |
| CN104632893A (en) * | 2014-12-25 | 2015-05-20 | 江南大学 | Porous hydrostatic pressure bearing structure based on hydrophobic interfaces |
| WO2018210370A1 (en) * | 2017-05-17 | 2018-11-22 | Schaeffler Technologies AG & Co. KG | Wheel-hub rolling element bearing assembly having a hydrophobic coating |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023226779A1 (en) * | 2022-05-24 | 2023-11-30 | 苏州心岭迈德医疗科技有限公司 | Catheter interventional heart pump |
| CN115227964A (en) * | 2022-09-21 | 2022-10-25 | 深圳核心医疗科技有限公司 | Flow velocity control method and device |
| CN115227964B (en) * | 2022-09-21 | 2022-12-27 | 深圳核心医疗科技有限公司 | Flow velocity control method and device |
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| Publication number | Publication date |
|---|---|
| CN112237680B (en) | 2023-08-25 |
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