CN112213510A - Sample injector and protein analyzer - Google Patents

Sample injector and protein analyzer Download PDF

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Publication number
CN112213510A
CN112213510A CN202011180895.3A CN202011180895A CN112213510A CN 112213510 A CN112213510 A CN 112213510A CN 202011180895 A CN202011180895 A CN 202011180895A CN 112213510 A CN112213510 A CN 112213510A
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China
Prior art keywords
feeding
sample
unloading
claw
area
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Pending
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CN202011180895.3A
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Chinese (zh)
Inventor
张兆伟
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Genrui Biotech Inc
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Genrui Biotech Inc
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Priority to CN202011180895.3A priority Critical patent/CN112213510A/en
Publication of CN112213510A publication Critical patent/CN112213510A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821Identification of carriers, materials or components in automatic analysers nature of coded information
    • G01N2035/00831Identification of carriers, materials or components in automatic analysers nature of coded information identification of the sample, e.g. patient identity, place of sampling

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to the field of medical equipment, and discloses a sample injector and a protein analyzer, wherein the sample injector comprises: the device comprises a frame, a sample injection device, a sample treatment device and a sample unloading device, wherein the frame is provided with a feeding area, a sample injection area, a treatment area and an unloading area; the sample feeding mechanism is arranged on the rack and used for conveying the test tube rack on the feeding area to the sample feeding area; the feeding mechanism is arranged on the rack and used for transmitting the test tube rack on the sample injection area to the processing area; the unloading mechanism is arranged on the rack and used for conveying the test tube racks in the processing area to the unloading area; and the sampling mechanism, the feeding mechanism and the unloading mechanism are all connected with the control mechanism. Through the mode, the embodiment of the invention can realize automatic transportation of the sample to be detected from the blood analyzer to the protein analyzer.

Description

Sample injector and protein analyzer
Technical Field
The embodiment of the invention relates to the field of medical equipment, in particular to a sample injector and a protein analyzer.
Background
At present, a plurality of problems are caused by excessive use of antibiotics, particularly, drug resistance of individuals can be enhanced by long-term abuse of the antibiotics, and further, immunity of human bodies is reduced, so the hospitals adopt careful measures in reasonable use of the antibiotics, wherein a scheme adopted by most large hospitals is that after a human blood sample is subjected to leukocyte detection on a blood cell analyzer, items such as C-reactive protein (CRP) and Serum Amyloid A (SAA) are detected on a specific protein analyzer, and bacterial or viral infection is further confirmed to avoid excessive use of the antibiotics.
The inventor of this application discovers at the in-process that realizes this application that the sample size that detects is very big for large-and-medium-sized hospital, and traditional detection mode is through manual putting into the blood analysis appearance with the sample that will detect, and the back that finishes that the blood analysis appearance detects is manual again with the sample that will detect and take out then put into specific protein appearance and detect, has seriously restricted hospital detection efficiency, has delayed out report time.
Disclosure of Invention
The embodiment of the invention mainly solves the technical problem of providing a sample injector and a protein analyzer, which can realize automatic transportation of a sample to be detected from a blood analyzer to the protein analyzer.
In order to solve the technical problems, the invention adopts a technical scheme that: providing an injector, comprising:
the device comprises a frame, a sample injection device, a sample treatment device and a sample unloading device, wherein the frame is provided with a feeding area, a sample injection area, a treatment area and an unloading area;
the sample feeding mechanism is arranged on the rack and used for conveying the test tube rack on the feeding area to the sample feeding area;
the feeding mechanism is arranged on the rack and used for transmitting the test tube rack on the sample injection area to the processing area;
the unloading mechanism is arranged on the rack and used for conveying the test tube racks in the processing area to the unloading area;
and the sampling mechanism, the feeding mechanism and the unloading mechanism are all connected with the control mechanism.
Optionally, the rack is provided with a feeding guide slot from the feeding area to the sample feeding area, a processing guide slot from the sample feeding area to the processing area, and a discharging guide slot from the processing area to the unloading area;
the sample feeding mechanism is used for pushing the test tube rack to move from the feeding area to the sample feeding area along the feeding guide groove;
the feeding mechanism is used for pushing the test tube rack to move from the sample introduction area to the processing area along the processing guide groove;
the unloading mechanism is used for pushing the test tube rack to move to the processing area along the loading area and then move to the unloading area from the processing area.
Optionally, the sample injection mechanism comprises: the sample injection bottom plate, the sample injection guide rail, the sample injection push plate, the sample injection claw and the sample injection motor are arranged on the sample injection bottom plate;
the sample introduction guide rail is arranged on the sample introduction bottom plate, the sample introduction push plate is mounted on the sample introduction guide rail and can slide along the sample introduction guide rail, the sample introduction claw is arranged on the sample introduction push plate in a poking mode, the sample introduction claw can rotate around the sample introduction push plate, the sample introduction motor is arranged on the sample introduction bottom plate and is used for driving the sample introduction push plate to move along the sample introduction guide rail;
the frame is provided with the sampling guide slot of the feeding guide slot of intercommunication, advance a kind claw dial can certainly advance a kind guide slot and insert the feeding guide slot to the butt and promote the test-tube rack that is located the feeding guide slot.
Optionally, a limiting piece is arranged on the sample feeding push plate;
advance kind locating part be used for as advance kind claw dial certainly when the feeding district moves toward advancing kind of district, it is right advance kind claw dial carry on spacingly, so that advance kind claw dial keep stretching into in the feeding guide slot, work as advance kind claw dial certainly the feeding district is from during the feeding district motion, right advance kind claw dial carry on not spacingly, so that advance kind claw rotatable breaking away from when colliding the test-tube rack that is located the feeding guide slot.
Optionally, the feeding mechanism comprises: the feeding mechanism comprises a feeding bottom plate, a feeding guide rail, a feeding push plate, a feeding claw pull and a feeding motor;
the feeding guide rail is arranged on the feeding bottom plate, the feeding push plate is mounted on the feeding guide rail and can slide along the feeding guide rail, the feeding claw is arranged on the feeding push plate and can rotate around the feeding push plate, the feeding motor is arranged on the feeding bottom plate and is used for driving the feeding push plate to move along the feeding guide rail;
the frame is provided with the intercommunication handle the guide slot that feeds of guide slot, feed the claw and dial can certainly feed the guide slot and insert handle the guide slot to the butt and promote to be located handle the test-tube rack in the guide slot.
Optionally, a feeding limit part is arranged on the feeding push plate;
the feed locating part is used for working as the feed claw is dialled certainly when advancing the district and moving toward the feed district, it is right the feed claw is dialled and is carried on spacingly, so that the feed claw is dialled and is kept stretching into in the processing guide slot, work as the feed claw is dialled certainly when feeding the district and moving toward the feed district, it is not spacing to advance the claw to dial, so that the feed claw is dialled and is rotatable break away from behind the terminal or the head end collision frame plane of feed tank handle the guide slot.
Optionally, the unloading mechanism includes: the unloading device comprises an unloading bottom plate, an unloading guide rail, an unloading push plate and an unloading motor;
the unloading guide rail is arranged on the unloading bottom plate, the unloading push plate is arranged on the unloading guide rail and can slide along the unloading guide rail, the unloading motor is arranged on the unloading bottom plate, and the unloading motor is used for driving the unloading push plate to move along the unloading guide rail;
the uninstallation push pedal is provided with the propelling movement arm, the propelling movement arm is used for the uninstallation push pedal need with the test-tube rack butt test-tube rack and promotion when transporting to the uninstallation district the test-tube rack move in the guide slot of unloading.
A protein analyzer, comprising:
a host, the host comprising: a control center;
the analysis component is connected with the control center, is used for detecting samples and generating corresponding data, and transmits the corresponding data to the control center;
the sampling assembly is connected with the control center and is used for sampling from corresponding test tubes in the test tube rack and conveying sampled samples to the analysis assembly;
the sampler according to any one of the above embodiments, wherein the sampler is configured to transport the test tube rack to a predetermined position to be sampled.
Optionally, the sample injector further comprises a detection code scanning assembly, the detection code scanning assembly is arranged on the feeding mechanism, and the detection code scanning assembly is connected with the control mechanism;
wherein, it is used for detecting to detect sweep a yard subassembly the test-tube rack has or not the test tube, if have, then sweeps a yard to the test tube.
Optionally, the protein analyzer further comprises a refrigerating mechanism, the refrigerating mechanism is arranged on the rack and connected with the host, and the refrigerating mechanism is provided with a reagent placing position.
In the embodiment of the invention, the test tube rack is conveyed to the feeding mechanism through the sampling mechanism, then the test tube rack is conveyed to the unloading mechanism through the feeding mechanism, and the unloading mechanism unloads the test tube rack to complete the automatic loading and unloading process of the test tube rack.
Drawings
FIG. 1 is a schematic overall view of an embodiment of the sample injector of the present invention;
FIG. 2 is a schematic diagram of the internal structure of an embodiment of the sample injector of the present invention;
FIG. 3 is a schematic diagram of the connection relationship of an embodiment of the sample injector of the present invention;
FIG. 4 is a schematic view of a housing of an injector embodiment of the present invention;
FIG. 5 is a schematic view of a sample injection mechanism of an embodiment of the sample injector of the present invention;
FIG. 6 is a schematic view of the feed mechanism of an embodiment of the sample injector of the present invention;
FIG. 7 is a schematic view of the unloading mechanism of an embodiment of the sample injector of the present invention;
FIG. 8 is a schematic overall view of an embodiment of the protein analyzer of the present invention;
FIG. 9 is a schematic diagram of the connection relationship of the host computer of the protein analyzer of the present invention;
FIG. 10 is a schematic view of an analysis assembly of an embodiment of the protein analyzer of the present invention;
FIG. 11 is a schematic view of a sampling assembly of an embodiment of the protein analyzer of the present invention;
FIG. 12 is a schematic view of a refrigeration mechanism of an embodiment of the protein analyzer of the present invention;
FIG. 13 is another schematic view of a refrigeration mechanism of an embodiment of the protein analyzer of the present invention;
FIG. 14 is a schematic diagram of a code scanning assembly for detecting an embodiment of a protein analyzer of the present invention.
Detailed Description
In order to facilitate an understanding of the invention, the invention is described in more detail below with reference to the accompanying drawings and specific examples. It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for descriptive purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1, 2 and 3, the sample injector 1 includes a frame 11, a sample injection mechanism 12, a feeding mechanism 13, an unloading mechanism 14 and a control mechanism 17. The sample feeding mechanism 12, the feeding mechanism 13 and the unloading mechanism 14 are all arranged on the frame 11, and the sample feeding mechanism 12, the feeding mechanism 13 and the unloading mechanism 14 are all connected with the control mechanism 17. One end of the feeding mechanism 13 is connected with one end of the sample feeding mechanism 12, and the other end of the feeding mechanism 13 is connected with one end of the unloading mechanism 14.
Referring to fig. 4, the rack 11 is divided into a feeding area 111, a sample injection area 112, a processing area 113 and an unloading area 114, and the rack 11 is provided with a feeding channel 115, a processing channel 116, an unloading channel 117, a sample injection slot 118 and a feeding slot 119. The feeding guide slot 115 is arranged in the feeding area 111, the sample feeding slot 118 is arranged in the feeding guide slot 115, the processing guide slot 116 is arranged in the processing area 113, the feeding slot 119 is arranged in the processing area 113, and the unloading guide slot 117 is arranged in the unloading area 114. It should be noted that the feeding guide slot 115 is used for limiting the movement of the test tube rack in the feeding area 111, the processing guide slot 116 is used for limiting the movement of the test tube rack in the processing area 113, and the unloading guide slot 117 is used for limiting the movement of the test tube rack in the unloading area. The number of the sample feeding grooves 118 is two, and the two sample feeding grooves 118 are arranged on the plane of the rack 11 at intervals in parallel.
In the embodiment of the present invention, the loading chute 115 and the processing chute 116 are perpendicular to each other and the processing chute 116 and the unloading chute are perpendicular to each other, and the sample feeding chute 118 and the feeding chute 119 are perpendicular to each other.
Referring to fig. 5, the sample injection mechanism 12 includes: a sample feeding bottom plate 121, a sample feeding guide rail 122, a sample feeding push plate 123, a sample feeding claw 124 and a sample feeding power assembly comprising a sample feeding motor 125. The sample introduction bottom plate 121 is disposed on the rack 11, and the sample introduction bottom plate 121 is correspondingly disposed at one end of the sample introduction groove 118. Advance kind guide rail 122 set up in advance kind bottom plate 121, advance kind push pedal 123 set up in advance kind guide rail 122, advance kind push pedal 123 can follow advance kind guide rail 122 and slide, advance kind claw dial 124 set up in advance on kind push pedal 123 and advance kind claw dial 124 can wind advance kind push pedal 123 and rotate, advance kind power pack and connect advance kind push pedal 123. The sample feeding push plate 123 is driven by the sample feeding power assembly to slide along the sample feeding guide rail 122.
Further, be provided with on the kind push pedal 123 and advance a kind fastener 1231, advance a kind power component including advance a kind pivot 1251 and advance a kind hold-in range 1252, the quantity of advancing a kind pivot 1251 is two, two advance a kind pivot 1251 set up respectively in advance a kind bottom plate 121 both ends, advance a kind hold-in range 1252 and connect two advance a kind pivot 1251, one of them advance a kind pivot 1251 and connect advance a kind motor 125, advance a kind push pedal 123 and pass through advance a kind fastener 1231 joint and be in advance on the kind hold-in range 1252. When advance kind motor 125 and rotate, advance kind motor 125 and drive one advance kind pivot 1251 and rotate, one advance kind pivot 1251 and pass through advance kind hold-in range 1252 and drive another advance kind pivot 1251 and rotate, and then drive connect in advance kind push pedal 123 on the kind hold-in range 1252 removes.
In some embodiments, the sample feeding push plate 123 is provided with a sample feeding latch structure, the sample feeding power assembly is a sample feeding gear and a sample feeding rack, the number of the sample feeding gears is two, two the sample feeding gears are respectively arranged at two ends of the sample feeding bottom plate 121, the sample feeding rack is arranged at the sample feeding bottom plate 121 and is in gear connection with two sample feeding gears, the sample feeding push plate 123 passes through the sample feeding latch structure and the sample feeding rack is in gear connection, so that the sample feeding push plate 123 can pass through the driving of the sample feeding rack to slide along the sample feeding guide rail 122.
Dial 124 to above-mentioned kind push pedal 123 and kind claw, kind push pedal 123 is provided with and advances a kind locating part 1232 and advances a kind claw and dial the pivot (not shown), advance a kind claw and dial 124 eccentric settings and advance a kind rotating hole (not shown), advance a kind rotating hole cooperation advance a kind claw dial the pivot will advance a kind claw dial 124 rotate install in advance on the push pedal 123. In a natural state, the sample claw 124 is positioned at a claw sample feeding station under the action of gravity and the action of the sample feeding limiting part 1321. When the sampling mechanism 12 pushes the received test tube rack from the sampling initial position to the sampling end position, the sampling claw 124 is positioned at the claw-claw sampling station. When the claw dial moves from the sample introduction end position to the sample introduction initial position and contacts the next test tube rack at the sample introduction initial position, the sample introduction claw dial 124 rotates around the sample introduction rotating shaft 1251 under the blocking of the next test tube rack and rotates from the claw dial sample introduction station to the claw dial standby station until the sample introduction claw dial 124 returns to the sample introduction initial position. It should be noted that the number of the sample introduction rotating shafts 1251 and the sample introduction claw dials 124 is two, two sample introduction rotating shafts 1251 are respectively disposed on two sides of the sample introduction push plate 123, two sample introduction claw dials 124 are respectively mounted on two sample introduction rotating shafts 1251, and the two sample introduction claw dials 124 can move in the sample introduction groove 118.
In some embodiments, the sample injection motor 125 is a stepper motor.
In some embodiments, the sample injection mechanism 12 further comprises a first sample injection sensor 126 and a second sample injection sensor 127, the first sample injection sensor 126 and the second sample injection sensor 127 are disposed on the sample injection bottom plate 121, and the first sample injection sensor 126 is disposed at the sample injection end position, and the second sample injection sensor 127 is disposed at the sample injection start position. The first sample injection sensor 126 and the second sample injection sensor 127 are both connected to the control mechanism 17. The first sample feeding sensor 126 is used for detecting whether the sample feeding claw 124 moves to a sample feeding end position, and the second sample feeding sensor 127 is used for detecting whether the sample feeding claw 124 returns to a preset sample feeding start position. When the test tube rack moves to the sampling end point position under the action of the sampling claw 124, the first sampling sensor 126 sends a corresponding signal to the control mechanism 17, and the control mechanism 17 controls the sampling motor 125 to rotate reversely after receiving the corresponding signal sent by the first sampling sensor 126. When the sample feeding claw 124 moves from the sample feeding end position to the sample feeding start position under the driving of the sample feeding power assembly, the second sample feeding sensor 127 detects a corresponding signal and sends the corresponding signal to the control mechanism 17, and the control mechanism 17 controls the sample feeding motor 125 to stop rotating.
Referring to fig. 6, the feeding mechanism 13 includes a feeding base plate 131, a feeding guide rail 132, a feeding push plate 133, a feeding claw 134, and a feeding power assembly including a feeding motor 135. The feeding bottom plate 131 is disposed on the frame 11, the feeding bottom plate 131 is correspondingly disposed at one end of the feeding groove 119, the feeding guide rail 132 is disposed on the feeding bottom plate 131, the feeding push plate 133 is disposed on the feeding guide rail 132, the feeding push plate 133 is slidable along the feeding guide rail 132, the feeding claw catch 134 is disposed on the feeding push plate 133, the feeding claw catch 134 is rotatable around the feeding push plate 133, and the feeding power assembly is connected to the feeding push plate 133. The feeding push plate 133 slides along the feeding guide rail 132 under the driving of the feeding power assembly.
Further, the feeding push plate 133 is provided with a feeding engaging piece 1331, the feeding mechanism 13 further includes two feeding rotating shafts 1351 and a feeding timing belt 1352, the two feeding rotating shafts 1351 are respectively disposed at two ends of the feeding base plate 131, one feeding rotating shaft 1351 is connected to the feeding motor 135, the feeding timing belt 1352 is connected to the two feeding rotating shafts 1351, and the feeding push plate 133 is clamped to the feeding timing belt 1352 by the feeding engaging piece 1331. When the feeding motor 135 rotates, the feeding motor 135 drives one of the feeding rotating shafts 1351 to rotate, and one of the feeding rotating shafts 1351 drives the other feeding rotating shaft 1351 to rotate through the feeding timing belt 1352, thereby driving the feeding push plate 133 connected to the feeding timing belt 1352 to move.
In some embodiments, the feeding push plate 133 is provided with a feeding latch structure, the feeding power assembly includes two feeding gears and two feeding racks, the two feeding gears are respectively disposed at two ends of the feeding bottom plate 131, the feeding rack is disposed on the feeding bottom plate 131 and is in gear engagement with the two feeding gears, and the feeding push plate 133 is in gear engagement with the feeding rack through the feeding latch structure, so that the feeding push plate 133 can slide along the feeding guide rail 132 by being driven by the feeding rack.
For the feeding push plate 133 and the feeding claw dial 134, the feeding push plate 133 is provided with a feeding limiting piece 1332 and a feeding claw dial rotating shaft (not shown in the figure), the feeding claw dial 134 is eccentrically provided with a feeding claw dial hole, and the feeding claw dial hole is matched with the feeding claw dial rotating shaft to rotatably install the feeding claw dial 134 on the feeding push plate 133. In a natural state, the feeding claw 134 is located at a claw feeding station under the action of gravity and the feeding limiting piece 1332. When the feeding claw 134 moves under the action of the feeding power assembly and is exposed to the feeding groove 119, the feeding claw 134 is in a feeding station, and the feeding mechanism 13 pushes the test tube rack transmitted from the sampling mechanism 12 from a feeding initial position to a feeding final position. When the feeding claw 134 moves from the feeding end position to the feeding initial position under the action of the feeding power assembly, the feeding claw 134 is exposed to the feeding groove 119 and is contained below the plane of the machine frame 11 under the action of the plane of the machine frame 11 in the moving process, and at this time, the feeding claw 134 is in a feeding standby station.
In this embodiment of the application, the number of the feeding limiting pieces 1332, the feeding claw shifting shafts and the feeding claw shifting 134 is two, the two feeding claw shifting shafts are respectively disposed at two ends of the feeding push plate 133, and the two feeding limiting pieces 1332 are respectively disposed beside the two feeding claw shifting shafts correspondingly.
In some embodiments, the feed motor 135 is a stepper motor.
In some embodiments, the feeding mechanism 13 further includes a first feeding sensor 136 and a second feeding sensor (not shown), the first feeding sensor 136 and the second feeding sensor are disposed on the feeding base plate 131, the first feeding sensor 136 is disposed at the feeding end position, and the second feeding sensor is disposed at the feeding start position. The first feeding sensor 136 is configured to detect whether the feeding claw 134 moves to the feeding end position, and the second feeding sensor is configured to detect whether the feeding claw 134 returns to the feeding start position. When the test tube rack moves to the feeding end position under the action of the feeding claw dial 134, the first feeding sensor 136 sends a corresponding signal to the control mechanism 17 and sends the corresponding signal to the control mechanism 17, and the control mechanism 17 controls the feeding motor 135 to rotate reversely after receiving the corresponding signal sent by the first feeding sensor 136. When the feed claw 134 moves from the feed end position to the feed position under the driving of the feed power assembly, the second feed sensor detects a corresponding signal and sends the corresponding signal to the control mechanism 17, and the control mechanism 17 controls the motor to stop rotating.
Referring to fig. 7, the unloading mechanism 14 includes: an unloading floor 141, an unloading guide 142, an unloading pusher 143, and an unloading power assembly including an unloading motor 144. The unloading floor is provided on the frame 11. The unloading guide rail 142 is disposed on the unloading base plate 141, the unloading push plate 143 is disposed on the unloading guide rail 142, the unloading push plate 143 can slide along the unloading guide rail 142, and the unloading power assembly is connected to the unloading push plate 143. The unloading push plate 143 slides along the unloading guide rail 142 under the driving of the unloading power assembly.
Further, the unloading pushing plate 143 is provided with an unloading engaging structure 1431 and a pushing arm (not shown), the unloading power assembly includes two unloading rotating shafts 1441 and unloading synchronous belts 1442, the number of the unloading rotating shafts 1441 is two, the two unloading rotating shafts 1441 are respectively disposed at two ends of the unloading base plate 141, the unloading synchronous belts 1442 are connected to the two unloading rotating shafts 1441, one of the unloading rotating shafts 1441 is connected to the unloading motor 144, and the unloading pushing plate 143 is engaged with the unloading synchronous belts 1442 through the unloading engaging structure 1431. When the unloading motor 144 rotates, the unloading motor 144 drives one of the unloading rotating shafts 1441 to rotate, one of the unloading rotating shafts 1441 drives the other unloading rotating shaft 1441 to rotate through the unloading synchronous belt 1442, so as to drive the unloading push plate 143 connected to the unloading synchronous belt 1442 to move, and the unloading push plate pushes the test tube rack to move along the unloading guide groove 117 in the unloading area 114 through the push arm, so as to complete unloading of the test tube rack.
In some embodiments, the unloading push plate 143 is provided with an unloading latch structure, the unloading power components are two unloading gears and two unloading racks, the two unloading gears are respectively disposed at two ends of the unloading base plate 141, the unloading racks are disposed on the unloading base plate 141 and are in gear engagement with the two unloading gears, and the unloading push plate 143 is in gear engagement with the unloading racks through the unloading latch structure, so that the unloading push plate 143 can slide along the unloading rail 142 by being driven by the unloading racks.
In some embodiments, the unloading mechanism 14 further includes a first unloading sensor 145 and a second unloading sensor (not shown), the first unloading sensor 145 and the second unloading sensor are disposed on the unloading base plate 141, and the first unloading sensor 145 is disposed at the unloading end position and the second unloading sensor is disposed at the unloading start position. The first unloading sensor 145 and the second unloading sensor are both connected to the control mechanism 17, the first unloading sensor 145 is used for detecting whether the unloading push plate 143 moves to an unloading end position, and the second unloading sensor is used for detecting whether the unloading push plate 143 moves to an unloading start position. When the test tube rack moves to the unloading end position under the pushing of the unloading push plate 143, the first unloading sensor 145 sends a corresponding signal to the control mechanism 17, and the control mechanism 17 controls the unloading motor 144 to rotate reversely after receiving the corresponding signal sent by the first unloading sensor 145. When the unloading push plate 143 moves from the unloading end position to the unloading start position under the driving of the unloading power, the second unloading sensor detects a corresponding signal and sends the corresponding signal to the control mechanism 17, and the control mechanism 17 controls the unloading motor 144 to stop rotating.
In the embodiment of the present invention, the sample introduction mechanism 12 moves the test tube rack from the loading region 111 to the sample introduction region 112 along the loading guide slot 115, the feeding mechanism 13 moves the test tube rack from the sample introduction region 112 to the processing region 113 along the processing guide slot 116, and the unloading mechanism 14 moves the test tube rack from the processing region 113 to the unloading region 114 along the unloading guide slot, so as to complete an automatic process of loading and unloading the test tube rack, thereby improving the inspection efficiency.
The present application further provides an embodiment of a protein analyzer, referring to fig. 8, the protein analyzer 100 includes: the sample injector 1, the main unit 2, and the refrigerating unit 3 according to any of the above embodiments. The treatment area 113 of the sample injector 1 is connected to the main unit 2, and the refrigeration mechanism 3 is provided in the sample injector 1.
Referring to fig. 9, the host 2 includes an analyzing component 21, a sampling component 22 and a control center 23, and both the analyzing component 21 and the sampling component 22 are connected to the control center 23. The analysis component 21 is used to detect the sample and generate corresponding data, which is transmitted by the analysis component 21 to the control center 23. The sampling assembly 22 is used to sample respective test tubes in the tube rack and to transport the sampled samples to the analyzer.
Specifically, referring to fig. 10, the analysis assembly 21 includes a module base 211, a laser 212, a diaphragm 213, a photoelectric conversion plate 214, a shielding cover 215, a reaction cup group 216, a stirring motor 217, and a magnet 218. The laser 212, the diaphragm 213, the reaction cup set 216, the photoelectric conversion plate 214 and the shield cover 215 are all mounted on the module base 211 and are sequentially arranged along the optical axis of the laser 212. A laser 212 is connected to the control center 23, the laser 212 being adapted to emit laser light via an aperture 213 to a set of reaction cups 216 to provide a source of light for the test. The stop 213 is used to filter the laser light emitted from the laser 212 to filter out stray light. The reaction cup set 216 is used for providing a reaction site for antigen and antibody, and the reaction cup set 216 receives the laser light emitted from the laser 212 and transmits the scattered light to the photoelectric conversion panel 214. The photoelectric conversion plate 214 is connected with the control center 23, and the photoelectric conversion plate 214 is used for receiving the scattered light transmitted by the reaction cup group 216 and converting an optical signal into an electrical signal so as to realize the scattering turbidimetric principle. The shield case 215 provides a reference plane for the photoelectric conversion panel 214 and shields an external electromagnetic signal. The stirring motor 217 is connected with the control center 23, the magnet 218 is fixedly arranged on a rotating shaft of the stirring motor 217, and the reaction cup group 216 comprises reaction cups and heating blocks. The reaction cup is used for providing a reaction site for antigen and antibody, receives laser emitted by the laser 212 and transmits scattered light to the photoelectric conversion plate 214, a magnetic rod stirrer is placed in the reaction cup, and when the stirring motor 217 drives the magnet 218 to rotate, the magnetic rod stirrer rotates together, so that the antigen and antibody in the reaction cup are fully combined and reacted. The surface of the heating block is covered with a heating film for providing temperature conditions required for antigen-antibody reaction.
Referring to fig. 11, the sampling assembly 22 includes a sampling holder 221, a piercing holder 222, a feeding driving device 223, a piercing driving device 224, a sampling needle 225 and a swab 226. The puncture holder 222 is movably mounted on the sampling holder 221, the sampling needle 225 is movably mounted on the puncture holder 222, and the swab 226 is fixedly mounted on the puncture holder 222. The feeding driving device 223 is connected to the control center 23, the feeding driving device 223 is used for driving the puncture holder 222 to move along the horizontal direction, so that the sampling needle 225 mounted on the puncture holder 222 is located right above the test tube or reaction cup group 216, and the feeding driving device 223 can be implemented by a transmission manner of driving a belt by using a belt wheel. The puncture driving device 224 is connected to the control center 23, and the puncture driving device 224 is configured to drive the sampling needle 225 to move in the vertical direction, so that the sampling needle 225 located directly above the test tube or reaction cup set 216 extends into the test tube or reaction cup set 216, and since the puncture driving device 224 needs to drive the sampling needle 225 to complete a puncture action in the vertical direction, the puncture driving device 224 is preferably implemented by using a screw transmission manner. The sampling needle 225 is used to aspirate and spit the sample and/or the antibody. The swab 226 is used to clean the sampling needle 225 as the sampling needle 225 is moved.
Referring to fig. 12 and 13, the refrigeration mechanism 3 includes a placing module 31 and a refrigeration module 32, and the refrigeration module 32 is attached to and connected with the placing module 31. Specifically, the placing module 31 is provided with two placing cavities 311, and the two placing cavities 311 can be used for placing two reagent bottles with the same specification or two reagent bottles with different specifications at the same time. When the sampling assembly takes a sample from the test tube, the sampling assembly moves to one of the two reagent bottles in the placing cavity 311 and reacts with the antigen or antibody placed in the reagent bottle.
Specifically, the refrigeration module 32 includes a refrigeration compartment 321, insulation cotton 322, a refrigeration sheet 323, and a refrigeration fan 324. The heat preservation cotton 322 is arranged outside the refrigerating chamber 321, the placing module 31 is contained in the heat preservation cotton 322, the refrigerating sheet 323 is arranged in the refrigerating chamber 321, the cold end of the refrigerating sheet 323 is attached to the inner wall of the refrigerating chamber 321 close to the placing cavity 311, the hot end of the refrigerating sheet 323 faces the refrigerating fan 324, and the refrigerating fan 324 is arranged on the surface of the refrigerating chamber 321 departing from the placing module 31. The refrigerating bin 321 is refrigerated through the refrigerating sheet 323 and cools and maintains the temperature of the preventing module through the heat insulation cotton 322, and the refrigerating fan 324 maintains the refrigerating effect of the refrigerating sheet 323 by performing air cooling and heat dissipation on the heat of the refrigerating sheet 323.
Further, a temperature control switch (not shown) and a temperature sensor (not shown) are embedded in the refrigeration sheet 323, the temperature control switch and the temperature sensor are arranged at the hot end of the refrigeration sheet 323, the temperature control switch and the temperature sensor are connected with the control center 23, and the temperature control switch is also connected with the refrigeration fan 324. When the temperature of the hot end of the refrigeration sheet 323 is too high, the temperature sensor transmits an overheat signal to the control center 23, the control center 23 transmits a heat dissipation signal to the temperature control switch, and the temperature control switch controls to increase the rotating speed of the refrigeration fan 324 so as to obtain a better heat dissipation effect, thereby ensuring the temperature stability of the module.
The sampler 1 further comprises a code scanning detection module 15, referring to fig. 14, wherein the code scanning detection module 15 comprises: a vertical motion component and a rotary scanning component, both of which are connected to the control mechanism 17. The rotary scanning assembly comprises a swing arm 151, a correlation optical coupler 152, a rotary motor 153, a rotary rubber sleeve 154 and a scanning plate 155. Swing arm 151 symmetry is provided with two opto-coupler mounting panels 1511, the quantity of correlation opto-coupler 152 is two, and two correlation opto-couplers 152 are installed respectively in two on the opto-coupler mounting panel 1511, swing arm 151 still is provided with mounting hole (not shown in the figure), mounting hole sets up in two between the opto-coupler mounting panel 1511, rotating electrical machines 153 passes through mounting hole install in swing arm 151, and rotating electrical machines 153's pivot is passed through mounting hole is towards the direction of two pair even mounting panels, rotatory gum cover 154 is connected and is fixed in rotating electrical machines 153's rotation axis, scanning plate 155 set up in swing arm 151, whether scanning plate 155 is used for the scanning to transport to the test-tube rack of scanning plate 155 position in to have the test tube.
The vertical motion assembly comprises a code-detecting and scanning base plate 156, a vertical guide rail 157, a vertical power module 158 and a position sensor 159, wherein the vertical guide rail 157 is arranged on the code-detecting and scanning base plate 156, the swing arm 151 is slidably arranged on the vertical guide rail 157, the swing arm 151 is connected with the vertical power module 158, the swing arm 151 can slide along the vertical guide rail 157 under the action of the vertical power module 158, the position sensor 159 is connected with the control mechanism 17, and the position sensor 159 is used for detecting whether the swing arm 151 moves to a predetermined test tube picking position. When swing arm 151 is in move to predetermined test tube pick-up position under perpendicular power module 158's the forward power take off, the sensor will transmit signal extremely control mechanism 17, control mechanism 17 stops perpendicular power module 158 work, this moment rotatory gum cover 154 cover gets the test tube, then control mechanism 17 is right after the time of predetermineeing power module carries out power take off until swing arm 151 replies the initial position, this moment rotating electrical machines 153 rotates, the test tube rotates under rotatory gum cover 154's drive, it is right to penetrate opto-coupler 152 the test tube sweeps the sign indicating number discernment to transmit information to control mechanism 17. In the embodiment of the present application, the vertical power module 158 is a belt pulley structure driven by a stepping motor, and the swing arm 151 is fixed on the belt by bolts.
The sample injector 1 will the test-tube rack is followed the material loading district 111 is transported to the district 112 of advancing, then the test-tube rack in the district 112 of advancing transports to the in-process of handling area 113, it is right to sweep a yard detection mechanism the test-tube rack detects, detects whether the test-tube rack has the test tube, if there is the test tube then right the test tube sweeps a yard, then sampling component 22 samples the test tube and send the sample to analysis component 21 carries out sample analysis, analysis component 21 with the analysis data transfer to control center 23.
It should be noted that the description of the present invention and the accompanying drawings illustrate preferred embodiments of the present invention, but the present invention may be embodied in many different forms and is not limited to the embodiments described in the present specification, which are provided as additional limitations to the present invention and to provide a more thorough understanding of the present disclosure. Moreover, the above technical features are combined with each other to form various embodiments which are not listed above, and all the embodiments are regarded as the scope of the present invention described in the specification; further, modifications and variations will occur to those skilled in the art in light of the foregoing description, and it is intended to cover all such modifications and variations as fall within the true spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. An injector, comprising:
the device comprises a frame, a sample injection device, a sample treatment device and a sample unloading device, wherein the frame is provided with a feeding area, a sample injection area, a treatment area and an unloading area;
the sample feeding mechanism is arranged on the rack and used for conveying the test tube rack on the feeding area to the sample feeding area;
the feeding mechanism is arranged on the rack and used for transmitting the test tube rack on the sample injection area to the processing area;
the unloading mechanism is arranged on the rack and used for conveying the test tube racks in the processing area to the unloading area;
and the sampling mechanism, the feeding mechanism and the unloading mechanism are all connected with the control mechanism.
2. The sample injector of claim 1, in which the housing is provided with a feed channel from the feed zone to the sample inlet zone, a treatment channel from the sample inlet zone to a treatment zone, and a discharge channel from the treatment zone to a discharge zone;
the sample feeding mechanism is used for pushing the test tube rack to move from the feeding area to the sample feeding area along the feeding guide groove;
the feeding mechanism is used for pushing the test tube rack to move from the sample introduction area to the processing area along the processing guide groove;
the unloading mechanism is used for pushing the test tube rack to move from the processing area to the unloading area.
3. The sample injector of claim 2, in which the sample injection mechanism comprises: the sample injection bottom plate, the sample injection guide rail, the sample injection push plate, the sample injection claw and the sample injection motor are arranged on the sample injection bottom plate;
the sample introduction guide rail is arranged on the sample introduction bottom plate, the sample introduction push plate is mounted on the sample introduction guide rail and can slide along the sample introduction guide rail, the sample introduction claw is arranged on the sample introduction push plate in a poking mode, the sample introduction claw can rotate around the sample introduction push plate, the sample introduction motor is arranged on the sample introduction bottom plate and is used for driving the sample introduction push plate to move along the sample introduction guide rail;
the frame is provided with the sampling guide slot of the feeding guide slot of intercommunication, advance a kind claw dial can certainly advance a kind guide slot and insert the feeding guide slot to the butt and promote the test-tube rack that is located the feeding guide slot.
4. The sample injector of claim 3, wherein a sample limit member is arranged on the sample push plate;
advance kind locating part be used for as advance kind claw dial certainly when the feeding district moves toward advancing kind of district, it is right advance kind claw dial carry on spacingly, so that advance kind claw dial keep stretching into in the feeding guide slot, work as advance kind claw dial certainly the feeding district is from during the feeding district motion, right advance kind claw dial carry on not spacingly, so that advance kind claw rotatable breaking away from when colliding the test-tube rack that is located the feeding guide slot.
5. The sample injector of claim 2, in which the feed mechanism comprises: the feeding mechanism comprises a feeding bottom plate, a feeding guide rail, a feeding push plate, a feeding claw pull and a feeding motor;
the feeding guide rail is arranged on the feeding bottom plate, the feeding push plate is mounted on the feeding guide rail and can slide along the feeding guide rail, the feeding claw is arranged on the feeding push plate and can rotate around the feeding push plate, the feeding motor is arranged on the feeding bottom plate and is used for driving the feeding push plate to move along the feeding guide rail;
the frame is provided with the intercommunication handle the guide slot that feeds of guide slot, feed the claw and dial can certainly feed the guide slot and insert handle the guide slot to the butt and promote to be located handle the test-tube rack in the guide slot.
6. The sample injector of claim 5, wherein the feed push plate is provided with a feed stop;
the feed locating part is used for working as the feed claw is dialled certainly when advancing the district and moving toward the feed district, it is right the feed claw is dialled and is carried on spacingly, so that the feed claw is dialled and is kept stretching into in the processing guide slot, work as the feed claw is dialled certainly when feeding the district and moving toward the feed district, it is not spacing to advance the claw to dial, so that the feed claw is dialled and is rotatable break away from behind the terminal or the head end collision frame plane of feed tank handle the guide slot.
7. The sample injector of claim 2, in which the unloading mechanism comprises: the unloading device comprises an unloading bottom plate, an unloading guide rail, an unloading push plate and an unloading motor;
the unloading guide rail is arranged on the unloading bottom plate, the unloading push plate is arranged on the unloading guide rail and can slide along the unloading guide rail, the unloading motor is arranged on the unloading bottom plate, and the unloading motor is used for driving the unloading push plate to move along the unloading guide rail;
the uninstallation push pedal is provided with the propelling movement arm, the propelling movement arm is used for the uninstallation push pedal need with the test-tube rack butt test-tube rack and promotion when transporting to the uninstallation district the test-tube rack move in the guide slot of unloading.
8. A protein analyzer, comprising:
a host, the host comprising: a control center;
the analysis component is connected with the control center, is used for detecting samples and generating corresponding data, and transmits the corresponding data to the control center;
the sampling assembly is connected with the control center and is used for sampling from corresponding test tubes in the test tube rack and conveying sampled samples to the analysis assembly;
the injector of any of claims injector-7, the injector to transport the rack to a pre-set location to be sampled.
9. The protein analyzer of claim 8, wherein the sample injector further comprises a detection barcode assembly, the detection barcode assembly is disposed on the feeding mechanism, and the detection barcode assembly is connected to the control mechanism;
wherein, it is used for detecting to detect sweep a yard subassembly the test-tube rack has or not the test tube, if have, then sweeps a yard to the test tube.
10. The protein analyzer of claim 8, further comprising a refrigeration mechanism disposed on the rack and connected to the control center, the refrigeration mechanism being provided with a reagent placement site.
CN202011180895.3A 2020-10-29 2020-10-29 Sample injector and protein analyzer Pending CN112213510A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011180895.3A CN112213510A (en) 2020-10-29 2020-10-29 Sample injector and protein analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011180895.3A CN112213510A (en) 2020-10-29 2020-10-29 Sample injector and protein analyzer

Publications (1)

Publication Number Publication Date
CN112213510A true CN112213510A (en) 2021-01-12

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011180895.3A Pending CN112213510A (en) 2020-10-29 2020-10-29 Sample injector and protein analyzer

Country Status (1)

Country Link
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114755436A (en) * 2022-06-13 2022-07-15 深圳市帝迈生物技术有限公司 Sample detection control method, system and control equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114755436A (en) * 2022-06-13 2022-07-15 深圳市帝迈生物技术有限公司 Sample detection control method, system and control equipment

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