CN112190623A - Traditional Chinese medicine composition for treating hyperplasia of mammary glands and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating hyperplasia of mammary glands and preparation method thereof Download PDF

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CN112190623A
CN112190623A CN202011288658.9A CN202011288658A CN112190623A CN 112190623 A CN112190623 A CN 112190623A CN 202011288658 A CN202011288658 A CN 202011288658A CN 112190623 A CN112190623 A CN 112190623A
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traditional chinese
medicine composition
chinese medicine
mammary glands
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李新建
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperplasia of mammary glands, which comprises the following raw materials in parts by weight: 4-8 parts of summer withered balls; 6-10 parts of ricepaper pith; 2-4 parts of green tangerine peels; 4-6 parts of angelica; 4-6 parts of white mustard seed; 8-12 parts of semen trichosanthis; 4-6 parts of kudzu root; 6-10 parts of radix bupleuri; the invention uniformly mixes the raw materials after crushing; adding 400 ml of cold water, soaking for 30 minutes, then decocting with strong fire, and then decocting with slow fire until 100 ml of the mixture remains; filtering the mixture, separating the medicine residue and the liquid medicine, adding 300 ml of water into the medicine residue, decocting with strong fire, and decocting with slow fire until the residual 100 ml of the mixture is obtained; filtering the mixture again to separate the residue from the medicinal liquid to obtain medicinal liquid again, and mixing the medicinal liquids obtained twice; the traditional Chinese medicine composition has the advantages of effectively treating hyperplasia of mammary glands, being strong in applicability and high in success rate, promoting blood circulation to remove blood stasis, promoting qi and milk secretion, regulating menstruation and dredging collaterals, clearing heat and relieving pain, improving immunity and reducing recurrence rate.

Description

Traditional Chinese medicine composition for treating hyperplasia of mammary glands and preparation method thereof
Technical Field
The invention belongs to the technical field of medicaments for treating hyperplasia of mammary glands, and particularly relates to a traditional Chinese medicine composition for treating hyperplasia of mammary glands and a preparation method thereof.
Background
Hyperplasia of mammary glands, neither tumor nor inflammation, from histological findings: is hyperplasia and degeneration of mammary gland tissue, and is closely related to endocrine dysfunction. Hyperplasia of mammary glands occurs well in middle-aged women, as well as in adolescents and postmenopausal women, and 50-70% of the occupational women in the large cities have hyperplasia of mammary glands in different degrees at present. Hyperplasia of mammary glands often manifests as breast pain and breast palpation of nodules, whose harm does not reside in the disease itself, but rather psychological stress, fearing that one may not suffer from breast cancer or may later become cancerous. There are many pathological types of hyperplasia of mammary glands, such as simple lobular hyperplasia (which accounts for most of hyperplasia of mammary glands), and the hyperplasia of mammary glands can be gradually relieved as long as the mental state is adjusted and the pressure is relieved. If the hyperplasia of lobule of mammary gland is accompanied with hyperplasia of ductal epithelium and presents severe abnormal shape, it is a precancerous lesion (a few), and it needs to be treated carefully and actively.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating hyperplasia of mammary glands and a preparation method thereof, which have the advantages of effectively treating hyperplasia of mammary glands, strong applicability, high success rate, promoting blood circulation to remove blood stasis, promoting lactation, regulating menstruation and dredging collaterals, clearing heat and relieving pain, improving immunity and reducing recurrence rate.
In order to achieve the purpose, the invention provides the following technical scheme: the traditional Chinese medicine composition for treating the hyperplasia of mammary glands comprises the following raw materials in parts by weight: 4-8 parts of summer withered balls; 6-10 parts of ricepaper pith; 2-4 parts of green tangerine peels; 4-6 parts of angelica; 4-6 parts of white mustard seed; 8-12 parts of semen trichosanthis; 4-6 parts of kudzu root; 6-10 parts of bupleurum.
Preferably, the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 6g of selfheal balls; 8g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 10g of semen trichosanthis; 5g of kudzu root; 8g of radix bupleuri.
Preferably, the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 5g of selfheal balls; 7g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 11g of semen trichosanthis; 5g of kudzu root; 9g of radix bupleuri.
Preferably, the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 7g of selfheal balls; 9g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 9g of semen trichosanthis; 5g of kudzu root; 7g of radix bupleuri.
A preparation method of a traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following steps:
(1) pulverizing the raw materials in the weight ratio, and uniformly mixing;
(2) adding 400 ml of cold water, soaking for 30 minutes, then decocting with strong fire, and then decocting with slow fire until 100 ml of the mixture remains;
(3) filtering the mixture, separating the medicine residue and the liquid medicine, adding 300 ml of water into the medicine residue, decocting with strong fire, and decocting with slow fire until the residual 100 ml of the mixture is obtained;
(4) filtering the mixture again to separate the residue from the medicinal liquid to obtain medicinal liquid again, and mixing the medicinal liquids obtained at two times.
The taking method of the traditional Chinese medicine composition for treating the hyperplasia of mammary glands comprises the steps of mixing the liquid medicines obtained in the two times, dividing the mixed liquid medicine into two parts, and taking one part in the morning and the evening respectively.
Compared with the prior art, the invention has the following beneficial effects:
the summer-heat-clearing pill has the effects of softening hardness and dissipating stagnation, can treat scrofula and thyromegaly, can clear liver fire and solve conjunctival congestion and swelling pain;
medulla Tetrapanacis has effects of clearing heat, promoting diuresis, promoting qi circulation, promoting lactation, resisting inflammation and oxidation, and has effects on qi stagnation and stagnation of qi of liver;
the green tangerine peel has obvious effects on swelling and pain of chest and ribs, hernia pain, mammary gland and breast pain;
the angelica is gynecological ginseng, has the effects of tonifying qi, nourishing blood, promoting blood circulation, regulating menstruation, relieving pain, moistening dryness, lubricating intestines, regulating qi and blood, promoting hematopoiesis, resisting liver injury, improving immunity, resisting tumors, reducing blood fat and the like;
semen Sinapis Albae has effects of promoting qi circulation, eliminating phlegm, dredging collaterals, relieving pain, relieving swelling, dispelling cold, regulating qi-flowing, and resolving hard mass;
semen Trichosanthis has effects of clearing lung heat, relieving chest stuffiness, resolving hard mass, promoting qi circulation, relieving chest stuffiness, relieving swelling, and expelling pus;
radix Puerariae has effects of promoting fluid production to quench thirst, clearing away heat, invigorating yang, relieving diarrhea, dredging meridian passage, and clearing away heat and toxic materials. Can dilate blood vessel, improve microcirculation, and has effects in treating myocardial infarction, arrhythmia, and arteriosclerosis;
the radix bupleuri has the effects of soothing liver-qi stagnation, dispelling heat, lifting yang qi, nourishing blood and liver, and remarkably improving immunity on breast swelling pain, agglomeration, abnormal secretion and axillary mass;
the invention can effectively treat hyperplasia of mammary glands, and the effective rate reaches more than 97 percent; the applicability is strong, the effect is obvious for women of all ages, eight traditional Chinese medicines are adopted, and no toxic or side effect is caused; the success rate is high, and the cure rate reaches over 86 percent; promoting blood circulation, removing blood stasis, promoting qi circulation, promoting lactation, regulating menstruation, dredging collaterals, clearing heat, relieving pain, regulating qi, resolving hard mass, improving immunity, and reducing recurrence rate which is not more than 2%.
Detailed Description
The technical solutions of the present invention are described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The embodiment provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands, which comprises the following raw materials in parts by weight: 6g of selfheal balls; 8g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 10g of semen trichosanthis; 5g of kudzu root; 8g of radix bupleuri.
Example 2
The embodiment provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands, which comprises the following raw materials in parts by weight: 5g of selfheal balls; 7g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 11g of semen trichosanthis; 5g of kudzu root; 9g of radix bupleuri.
Example 3
The embodiment provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands, which comprises the following raw materials in parts by weight: 7g of selfheal balls; 9g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 9g of semen trichosanthis; 5g of kudzu root; 7g of radix bupleuri.
The invention provides a preparation method of a traditional Chinese medicine composition for treating hyperplasia of mammary glands, which comprises the following steps: (1) crushing the raw materials in any one of the embodiments according to the weight ratio, and then uniformly mixing; (2) adding 400 ml of cold water, soaking for 30 minutes, then decocting with strong fire, and then decocting with slow fire until 100 ml of the mixture remains; (3) filtering the mixture, separating the medicine residue and the liquid medicine, adding 300 ml of water into the medicine residue, decocting with strong fire, and decocting with slow fire until the residual 100 ml of the mixture is obtained; (4) filtering the mixture again to separate the residue from the medicinal liquid to obtain medicinal liquid again, and mixing the medicinal liquids obtained at two times.
The invention provides a method for taking a traditional Chinese medicine composition for treating hyperplasia of mammary glands. The liquid medicine is taken in the same day, and needs to be refrigerated at intervals to avoid putrefaction and deterioration and reduce curative effect.
Case statistics: randomly drawing 100 cases of patients with mammary gland hyperplasia, wherein the patients are 38 cases of patients with mammary gland hyperplasia at the age of 25-35 (not containing), and 56 cases of patients with mammary gland hyperplasia at the age of 35 (containing) -45 (not containing); age 45 (inclusive) -6 cases at age 49 years;
diagnostic criteria: the patient has obvious mammary gland pain; irregular nodules with different sizes can be touched and pushed; pain or has spread to the underarm, shoulder and back;
treatment: the liquid medicine of the present invention was taken daily according to example 1; ten days is a treatment course, and 3-6 treatment courses are provided;
the taking effect is as follows: the pain is obviously relieved, the pain time is shortened, and the pain is not sensed; the nodules are reduced or not easy to touch until the nodules disappear; peripheral pain is eliminated, the pain range is reduced to no pain;
according to case statistics, 86 cases are cured and account for 86 percent; 97 cases have obvious effect accounting for 97 percent; one year after recovery, 2 relapse cases account for 2.
In clinical treatment, the invention is assisted by acupuncture and massage, and has quicker and better effect.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The traditional Chinese medicine composition for treating hyperplasia of mammary glands is characterized by comprising the following raw materials in parts by weight: 4-8 parts of summer withered balls; 6-10 parts of ricepaper pith; 2-4 parts of green tangerine peels; 4-6 parts of angelica; 4-6 parts of white mustard seed; 8-12 parts of semen trichosanthis; 4-6 parts of kudzu root; 6-10 parts of bupleurum.
2. The traditional Chinese medicine composition for treating hyperplasia of mammary glands according to claim 1, wherein the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 6g of selfheal balls; 8g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 10g of semen trichosanthis; 5g of kudzu root; 8g of radix bupleuri.
3. The traditional Chinese medicine composition for treating hyperplasia of mammary glands according to claim 1, wherein the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 5g of selfheal balls; 7g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 11g of semen trichosanthis; 5g of kudzu root; 9g of radix bupleuri.
4. The traditional Chinese medicine composition for treating hyperplasia of mammary glands according to claim 1, wherein the traditional Chinese medicine composition for treating hyperplasia of mammary glands comprises the following raw materials in parts by weight: 7g of selfheal balls; 9g of ricepaper pith; 3g of green tangerine peel; 5g of Chinese angelica; 5g of white mustard seed; 9g of semen trichosanthis; 5g of kudzu root; 7g of radix bupleuri.
5. The preparation method of the traditional Chinese medicine composition for treating mammary gland hyperplasia according to any one of claims 2 to 4, wherein the preparation method comprises the following steps: (1) pulverizing the raw materials in the weight ratio, and uniformly mixing; (2) adding 400 ml of cold water, soaking for 30 minutes, then decocting with strong fire, and then decocting with slow fire until 100 ml of the mixture remains; (3) filtering the mixture, separating the medicine residue and the liquid medicine, adding 300 ml of water into the medicine residue, decocting with strong fire, and decocting with slow fire until the residual 100 ml of the mixture is obtained; (4) filtering the mixture again to separate the residue from the medicinal liquid to obtain medicinal liquid again, and mixing the medicinal liquids obtained at two times.
6. The method of claim 5, wherein the two solutions are divided into two parts and administered one part in the morning and one part in the evening.
CN202011288658.9A 2020-11-17 2020-11-17 Traditional Chinese medicine composition for treating hyperplasia of mammary glands and preparation method thereof Pending CN112190623A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103536745A (en) * 2012-07-12 2014-01-29 马建民 Traditional Chinese medicinal watered pills for treating hyperplasia of mammary glands
CN104740132A (en) * 2013-12-25 2015-07-01 储海燕 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands
CN108079250A (en) * 2017-12-29 2018-05-29 杨凌寿康中医药保健品有限公司 A kind of herbal composite for treating the proliferation of mammary gland
CN111632089A (en) * 2020-07-10 2020-09-08 丹东瑞丰动物药业有限责任公司 Traditional Chinese medicine composition for treating cow mastitis and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103536745A (en) * 2012-07-12 2014-01-29 马建民 Traditional Chinese medicinal watered pills for treating hyperplasia of mammary glands
CN104740132A (en) * 2013-12-25 2015-07-01 储海燕 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands
CN108079250A (en) * 2017-12-29 2018-05-29 杨凌寿康中医药保健品有限公司 A kind of herbal composite for treating the proliferation of mammary gland
CN111632089A (en) * 2020-07-10 2020-09-08 丹东瑞丰动物药业有限责任公司 Traditional Chinese medicine composition for treating cow mastitis and preparation method thereof

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