CN112179736A - Biological safety collection processor for sputum microorganism detection and operation method thereof - Google Patents

Biological safety collection processor for sputum microorganism detection and operation method thereof Download PDF

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Publication number
CN112179736A
CN112179736A CN202011053010.3A CN202011053010A CN112179736A CN 112179736 A CN112179736 A CN 112179736A CN 202011053010 A CN202011053010 A CN 202011053010A CN 112179736 A CN112179736 A CN 112179736A
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sample
shell
cover
outlet
sputum
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CN202011053010.3A
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Chinese (zh)
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凌中鑫
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Anhui Guoke Biotechnology Co ltd
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Anhui Guoke Biotechnology Co ltd
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Priority to CN202011053010.3A priority Critical patent/CN112179736A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a sputum microorganism detection biological safety acquisition processor, wherein one end of a cylindrical shell is provided with an end cover, the other end of the cylindrical shell is sealed by a rear cover, a piston is arranged in the shell, the rear end of the piston is connected with one end of a push rod, the center of the rear cover is provided with a guide hole, the other end of the push rod extends out of the shell through the guide hole and is connected with a push handle, a waste liquid outlet is formed in the end cover, a partition plate is arranged at the position, close to the front end, of the shell and is a latticed plate, a first filtering membrane is fixed on the partition plate, convex sample ports are formed in the shell at two sides of the partition plate, a sponge layer is fixed on the piston, and cleaning cloth layers are arranged on opposite surfaces of. The processor has simple structure, can pre-process the sputum and can avoid pollution.

Description

Biological safety collection processor for sputum microorganism detection and operation method thereof
Technical Field
The invention relates to the technical field of body fluid specimen processing, in particular to a biosafety standard body fluid specimen processor.
Background
At present, clinical analysis and examination of body fluid samples such as sputum and the like are indispensable medical activities for determining etiology and monitoring disease conditions. The collection and processing of specimens by clinicians and doctors in medical and technical departments relate to the detection results of the specimens.
At present, containers used in clinical specimen collection and transportation and inspection processes are both open type and semi-open type, potential safety hazards of infectious pathogens exist, the specimens are polluted in the operation process, and the accuracy of subsequent detection results is seriously influenced.
Disclosure of Invention
The invention aims to solve the technical problem of realizing a biological safety collection processor for sputum microorganism detection, which can avoid the pollution to a sputum sample in the processing process and improve the accuracy of the detection result.
In order to achieve the purpose, the invention adopts the technical scheme that: sputum microorganism detects biological safety and gathers treater, cylindrical shell one end is equipped with the end cover, and the other end is sealed by the hou gai, be equipped with the piston in the shell, the piston rear end is connected with push rod one end, back lid center is equipped with the guiding hole, the other end of push rod stretches out the shell by the guiding hole and outer and with push away the handle and be connected, be equipped with the waste liquid export on the end cover, the shell is close to front position and is equipped with the baffle, the baffle is latticed board, be fixed with first filtration membrane on the baffle, all be equipped with convex sample mouth on the shell of baffle both sides, be fixed with the sponge layer on the piston, all be equipped with the hundred clean cloth layers on the facies of sponge layer and baffle.
The guiding hole is a circular hole, the push rod is of a cylindrical rod-shaped structure, and the outer diameter of the push rod is smaller than the inner diameter of the guiding hole.
The novel cleaning cloth is characterized in that a clamping groove is formed in the push rod, an inserting piece capable of being inserted or pulled out selectively is embedded in the clamping groove, the inserting piece is used as a limiting mechanism for pushing the push rod into the shell to move when being inserted into the clamping groove, and when the inserting piece contacts the rear cover, a gap is formed between the two cleaning cloth layers.
The sponge layer is filled with a pretreatment solution for pretreating the collected sample.
The waste liquid outlet comprises a connecting cover and a liquid outlet, one side of the connecting cover is an opening side, the other side of the connecting cover is connected with the liquid outlet, the edge of the opening side of the connecting cover is fixed on the shell, the outer circle of buckle structures of the waste liquid outlet are arranged, and the buckle structures are sleeved with waste liquid cups.
The end cover is a latticed plate, the first filtering membrane is fixed on the partition plate facing to one side of the rear cover, the scouring pad layer on the partition plate is fixed on the first filtering membrane, and the second filtering membrane is arranged on one side, facing to the partition plate, of the end cover.
The pores of the first filter membrane are larger than the pores of the second filter membrane.
The sample port on the shell between the partition plate and the end plate is a sample outlet for discharging liquid, the other sample port is a sample inlet for sucking liquid, sealing covers are arranged on the waste liquid outlet, the sample outlet and the sample inlet, and the sample outlet and the sample inlet are both provided with rubber hoses which are connected when the sealing covers are taken down.
The operation method of the sputum microorganism detection biosafety collection processor comprises the following steps:
step 1, taking down a sealing cover on a sample inlet, and sleeving a rubber hose on the sample inlet;
step 2, placing the rubber hose into a sample container, and pulling the push handle outwards to suck the sample into the shell;
step 3, taking down the insert;
step 4, pushing the push handle to enable the two layers of scouring pad layers to be in contact with each other, taking down the rubber hose on the sample inlet, and sleeving the seal cover on the sample inlet;
step 5, taking down the sealing cover on the sample outlet, enabling the sample outlet to face upwards, and pushing the push handle to enable the sample and the pretreatment solution to be injected into a cavity between the partition plate and the end cover;
step 6, sleeving a sealing cover on the sample inlet, and standing for a set time to enable the sample and the pretreatment solution to be fully reflected;
step 7, taking off the sealing cover on the sample outlet, and sleeving a rubber hose on the sample outlet;
step 8, pushing the push handle to lead the sample out of the rubber hose;
step 9, taking down the rubber hose on the sample outlet, and sleeving a sealing cover on the sample outlet;
and step 10, pushing a sealing cover on the waste liquid outlet to inject the waste liquid in the shell into the waste liquid cup by pushing a push handle.
And (5) after the step (4) is executed, rotating the push handle to enable the two scouring pad layers to crush the sputum, and then executing the step (5).
The invention can transfer the sputum sample to the processor without exposure, and the process can avoid the mutual pollution of the sample and the external environment; simultaneously the device can carry out physical treatment with clinical specimen, releases pathogen or other and waits to examine the material to some non-waiting to examine the material and get rid of through filter equipment, the filter membrane can effectually get rid of moisture and hold back the material of waiting to examine, will examine the material concentration of examining, be favorable to the detection in later stage. Whole sample collection and subsequent processing all are in inclosed container, can effectual protection medical staff and medical environment, also can promote the relevance ratio of sample and reduce the contaminated probability of sample simultaneously.
Drawings
The following is a brief description of the contents of each figure and the symbols in the figures in the description of the invention:
FIG. 1 is a schematic diagram of an acquisition processor architecture;
the labels in the above figures are: 1. a push handle; 2. a push rod; 3. a piston; 4. a sponge layer; 5. a first filter membrane; 6. a partition plate; 7. a second filter membrane; 8. an end cap; 9. a waste liquid cup; 10. a waste liquid outlet; 11. a sample outlet; 12. a sample inlet; 13. a housing; 14. a guide hole; 15. a rear cover; 16. a sealing cover; 17. a scouring pad layer.
Detailed Description
The following description of the embodiments with reference to the drawings is provided to describe the embodiments of the present invention, and the embodiments of the present invention, such as the shapes and configurations of the components, the mutual positions and connection relationships of the components, the functions and working principles of the components, the manufacturing processes and the operation and use methods, etc., will be further described in detail to help those skilled in the art to more completely, accurately and deeply understand the inventive concept and technical solutions of the present invention.
As shown in figure 1, the sputum microorganism detection biological safety collection processor, one end of a cylindrical shell 13 is provided with an end cover 8, the other end of the cylindrical shell is sealed by a rear cover 15, a piston 3 is arranged in the shell 13, the rear end of the piston 3 is connected with one end of a push rod 2, the center of the rear cover 15 is provided with a guide hole 14, the other end of the push rod 2 extends out of the shell 13 through the guide hole 14 and is connected with a push handle 1, and the end cover 8 is provided with a waste liquid outlet 10 to form a structure similar to an injector.
Waste liquid export 10 is opening side including connecting cover and liquid outlet, connecting cover one side, and the another side is connected with the liquid outlet, and the edge of the opening side of connecting cover is fixed on shell 13, and the outer round buckle structure of waste liquid export 10, the structural cover of buckle have waste liquid cup 9.
The shell 13 is close to the front position and is equipped with baffle 6, be fixed with first filtration membrane 5 on the baffle 6, the hole of first filtration membrane 5 can not let the macromolecule virus pass through, and can let the micromolecule of decomposition pass through, all be equipped with convex sample mouth on the shell 13 of baffle 6 both sides, the sample mouth that lies in on the shell 13 between baffle 6 and the end plate is for being used for the sample export 11 of discharge liquid, another sample mouth is the sample import 12 of inhaling liquid, waste liquid export 10, all be equipped with sealed lid 16 on sample export 11 and the sample import 12, sample export 11 and sample import 12 all are furnished with the rubber hose who connects when taking off sealed lid 16, the preferred thread cover structure of sealed lid 16, can avoid breaking away from when push rod 2 pushes down, also can guarantee the gas tightness.
Be fixed with sponge layer 4 on the piston 3, sponge layer 4 intussuseption is filled with the preliminary treatment solution that is used for the sample of preliminary treatment collection, preliminary treatment solution is decided according to the type of sample, baffle 6 and end cover 8 are latticed board, first filtration membrane 5 is fixed on baffle 6 towards 15 one side of back lid, scouring pad layer 17 on the baffle 6 is fixed on first filtration membrane 5, end cover 8 is equipped with second filtration membrane 7 towards 6 one side of baffle, can make baffle 6 and end cover 8 support filtration membrane like this, avoid filtration membrane to drop. The pores of the first filtering membrane 5 are larger than those of the second filtering membrane 7, and the second filtering membrane 7 only can allow water molecules to pass through and can not allow decomposed viruses to pass through, so that the decomposed viruses are left in the processor to wait for the uniform treatment of medical wastes later.
Sponge layer 4 and baffle 6 all are equipped with scouring pad layer 17 on the face in opposite directions, scouring pad layer 17 can the interact pulverize the sputum, make abundant being handled of sputum sample, and can be quick through first filtration membrane 5, guiding hole 14 is circular hole, push rod 2 is cylindrical shaft-like structure, the external diameter of push rod 2 is less than the internal diameter of guiding hole 14, make things convenient for rotatory push rod 2, push rod 2 and 3 rigid couplings of piston, then it is rotatory with the above scouring pad layer 17 to further drive piston 3, reach the purpose of pulverizing the sputum.
Be equipped with the draw-in groove on the push rod 2, the embedding has the inserted sheet that can choose to insert or extract in the draw-in groove, and when the inserted sheet inserted the draw-in groove as the stop gear of push rod 2 propelling movement in the shell 13, when the inserted sheet contacts back lid 15, has the clearance between two scouring pad layers 17, avoids the operation, promotes push rod 2 and extrudes the preliminary treatment solution in the sponge layer 4.
The operation method of the sputum microorganism detection biosafety acquisition processor comprises the following steps:
step 1, taking off a sealing cover 16 on a sample inlet 12, and sleeving a rubber hose on the sample inlet 12;
step 2, placing the rubber hose into a sample container, and pulling the push handle 1 outwards to suck the sample into the shell 13;
step 3, taking down the insert;
step 4, pushing the push handle 1 to enable the two scouring pad layers 17 to be in contact with each other, taking down the rubber hose on the sample inlet 12, sleeving the seal cover 16 on the sample inlet 12, and rotating the push handle 1 to enable the two scouring pad layers 17 to crush sputum;
step 5, removing the sealing cover 16 on the sample outlet 11, enabling the sample outlet 11 to face upwards, and pushing the push handle 1 to inject the sample and the pretreatment solution into a cavity between the partition plate 6 and the end cover 8;
step 6, sleeving the sample inlet 12 on a sealing cover 16, and standing for a set time to enable the sample and the pretreatment solution to be fully reflected;
step 7, removing the sealing cover 16 on the sample outlet 11, and sleeving a rubber hose on the sample outlet 11;
step 8, pushing the push handle 1 to lead the sample out of the rubber hose;
step 9, taking off the rubber hose on the sample outlet 11, and sleeving a sealing cover 16 on the sample outlet 11;
and step 10, pushing the push handle 1 by a sealing cover 16 on the waste liquid outlet 10 to inject the waste liquid in the shell 13 into the waste liquid cup 9.
In such an operation mode, the first filter membrane 5 cannot allow the viruses with large molecules to pass through, but only can allow the viruses to pass through after being inactivated and decomposed into small molecules, so that pollution can be avoided; after the sampling area comes out, the output liquid can not carry viruses, the second filtering membrane 7 can only filter out water molecules, and other toxic and harmful impurities can be left in the collector.
The invention has been described above with reference to the accompanying drawings, it is obvious that the invention is not limited to the specific implementation in the above-described manner, and it is within the scope of the invention to apply the inventive concept and solution to other applications without substantial modification.

Claims (10)

1. Sputum microorganism detects biological safety and gathers treater, cylindrical shell one end is equipped with the end cover, and the other end is sealed by the back lid, be equipped with the piston in the shell, the piston rear end is connected with push rod one end, back lid center is equipped with the guiding hole, the other end of push rod stretches out the shell by the guiding hole and outside and with push away the handle and be connected, be equipped with waste liquid outlet, its characterized in that on the end cover: the shell is close to the front end position and is equipped with the baffle, the baffle is latticed board, be fixed with first filtration membrane on the baffle, all be equipped with convex sample mouth on the shell of baffle both sides, be fixed with the sponge layer on the piston, all be equipped with the hundred clean cloth layers on the face in opposite directions of sponge layer and baffle.
2. The sputum microorganism detection biosafety collection processor of claim 1, wherein: the guiding hole is a circular hole, the push rod is of a cylindrical rod-shaped structure, and the outer diameter of the push rod is smaller than the inner diameter of the guiding hole.
3. The sputum microorganism detection biosafety collection processor of claim 2, wherein: the novel cleaning cloth is characterized in that a clamping groove is formed in the push rod, an inserting piece capable of being inserted or pulled out selectively is embedded in the clamping groove, the inserting piece is used as a limiting mechanism for pushing the push rod into the shell to move when being inserted into the clamping groove, and when the inserting piece contacts the rear cover, a gap is formed between the two cleaning cloth layers.
4. The sputum microorganism detection biosafety collection processor of claim 1, 2 or 3, wherein: the sponge layer is filled with a pretreatment solution for pretreating the collected sample.
5. The sputum microorganism detection biosafety collection processor of claim 4, wherein: the waste liquid outlet comprises a connecting cover and a liquid outlet, one side of the connecting cover is an opening side, the other side of the connecting cover is connected with the liquid outlet, the edge of the opening side of the connecting cover is fixed on the shell, the outer circle of buckle structures of the waste liquid outlet are arranged, and the buckle structures are sleeved with waste liquid cups.
6. The sputum microorganism detection biosafety collection processor of claim 1 or 5, wherein: the end cover is a latticed plate, the first filtering membrane is fixed on the partition plate facing to one side of the rear cover, the scouring pad layer on the partition plate is fixed on the first filtering membrane, and the second filtering membrane is arranged on one side, facing to the partition plate, of the end cover.
7. The sputum microorganism detection biosafety collection processor of claim 6, wherein: the pores of the first filter membrane are larger than the pores of the second filter membrane.
8. The sputum microorganism detection bio-safety collection processor of claim 7, wherein: the sample port on the shell between the partition plate and the end plate is a sample outlet for discharging liquid, the other sample port is a sample inlet for sucking liquid, sealing covers are arranged on the waste liquid outlet, the sample outlet and the sample inlet, and the sample outlet and the sample inlet are both provided with rubber hoses which are connected when the sealing covers are taken down.
9. The method of operating a sputum microorganism detection biosafety collection processor as recited in claims 1-8, wherein:
step 1, taking down a sealing cover on a sample inlet, and sleeving a rubber hose on the sample inlet;
step 2, placing the rubber hose into a sample container, and pulling the push handle outwards to suck the sample into the shell;
step 3, taking down the insert;
step 4, pushing the push handle to enable the two layers of scouring pad layers to be in contact with each other, taking down the rubber hose on the sample inlet, and sleeving the seal cover on the sample inlet;
step 5, taking down the sealing cover on the sample outlet, enabling the sample outlet to face upwards, and pushing the push handle to enable the sample and the pretreatment solution to be injected into a cavity between the partition plate and the end cover;
step 6, sleeving a sealing cover on the sample inlet, and standing for a set time to enable the sample and the pretreatment solution to be fully reflected;
step 7, taking off the sealing cover on the sample outlet, and sleeving a rubber hose on the sample outlet;
step 8, pushing the push handle to lead the sample out of the rubber hose;
step 9, taking down the rubber hose on the sample outlet, and sleeving a sealing cover on the sample outlet;
and step 10, pushing a sealing cover on the waste liquid outlet to inject the waste liquid in the shell into the waste liquid cup by pushing a push handle.
10. The operating method according to claim 9, characterized in that: and (5) after the step (4) is executed, rotating the push handle to enable the two scouring pad layers to crush the sputum, and then executing the step (5).
CN202011053010.3A 2020-09-29 2020-09-29 Biological safety collection processor for sputum microorganism detection and operation method thereof Pending CN112179736A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112082839A (en) * 2020-09-29 2020-12-15 安徽国科生物科技有限公司 Sputum specimen collecting robot and control method thereof
CN112082844A (en) * 2020-09-29 2020-12-15 安徽国科生物科技有限公司 Intelligent biological specimen safe collection processing system and control method
CN114053072A (en) * 2021-11-17 2022-02-18 濮阳市第五人民医院 Tuberculosis clinical sample sampling device

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CN212391313U (en) * 2020-09-29 2021-01-22 安徽国科生物科技有限公司 Automatic sputum sample processing system
CN212391308U (en) * 2020-09-29 2021-01-22 安徽国科生物科技有限公司 Biological safety type body fluid specimen processing device
CN214334411U (en) * 2020-09-28 2021-10-01 安徽国科生物科技有限公司 Saliva nucleic acid detection biosafety acquisition processor
CN215262691U (en) * 2020-09-29 2021-12-21 安徽国科生物科技有限公司 Automatic system for safely collecting and processing sputum sample

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CN112082844A (en) * 2020-09-29 2020-12-15 安徽国科生物科技有限公司 Intelligent biological specimen safe collection processing system and control method
CN114053072A (en) * 2021-11-17 2022-02-18 濮阳市第五人民医院 Tuberculosis clinical sample sampling device

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