CN112168939A - Traditional Chinese medicine composition for treating urinary calculus - Google Patents
Traditional Chinese medicine composition for treating urinary calculus Download PDFInfo
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- CN112168939A CN112168939A CN202011076905.9A CN202011076905A CN112168939A CN 112168939 A CN112168939 A CN 112168939A CN 202011076905 A CN202011076905 A CN 202011076905A CN 112168939 A CN112168939 A CN 112168939A
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- chinese medicine
- traditional chinese
- medicine composition
- urinary calculus
- treating urinary
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
- A61K36/835—Aquilaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Abstract
The invention discloses a traditional Chinese medicine composition for treating urinary calculus, which consists of the following raw materials: herba Lysimachiae Christinae, cortex Ulmi Pumilae, spora Lygodii, folium Pyrrosiae, endothelium corneum Gigeriae Galli, radix Curcumae, Achyranthis radix, and lignum Aquilariae Resinatum. The traditional Chinese medicine composition can clear heat, promote urination, promote qi circulation and remove urinary calculus, is suitable for urinary calculus patients, has no adverse reaction, and has stable curative effect.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating kidney stones.
Background
Renal calculus is caused by abnormal accumulation of crystalline substances (such as calcium, oxalic acid, uric acid, cystine, and the like) in the kidney, and is a common disease and frequently encountered disease of the urinary system, and more frequently encountered diseases in men than in women. 40-75% of patients with renal calculus have lumbago of different degrees. Large stones with small mobility, manifested as soreness and distension of the waist, or dull pain during increased physical activity. The colic caused by small stones often suddenly causes severe pain of incised sample of waist and abdomen, and is paroxysmal. Calculus can occur in any part of the urinary system, but usually originates from kidney, and when kidney calculus is formed, the calculus is mostly located in renal pelvis or renal calyx and can be discharged into ureter and bladder, and almost all calculus of ureter comes from kidney. In addition to causing pain, calculus can also lead to acute and chronic renal insufficiency, and even the possibility of renal failure. The current treatment means of western medicine include pain relief, infection control and surgical stone or gravel removal, which are expensive and have many adverse effects, especially for the elderly patients, with limited efficacy.
Therefore, there is a need to provide a Chinese medicinal composition for treating urinary calculus, which solves the above problems.
Disclosure of Invention
In order to solve the technical problems, the invention provides the traditional Chinese medicine composition for treating urinary calculus, which is suitable for patients with various types of urinary calculus, has no adverse reaction and stable curative effect.
The invention provides a traditional Chinese medicine composition for treating urinary calculus, which is prepared from the following raw materials: herba Lysimachiae Christinae, cortex Ulmi Pumilae, spora Lygodii, folium Pyrrosiae, endothelium corneum Gigeriae Galli, radix Curcumae, Achyranthis radix, and lignum Aquilariae Resinatum.
The further scheme is that the feed is prepared from the following raw materials in parts by weight: 60-120 g of longhairy antenoron herb, 20-40 g of elm root bark, 20-40 g of lygodium japonicum, 20-40 g of pyrrosia lingua, 10-20 g of chicken's gizzard-membrane, 10-20 g of turmeric root-tuber, 10-20 g of twotooth achyranthes root and 10-20 g of agilawood.
The further scheme is that the feed is prepared from the following raw materials by weight: 60 g of longhairy antenoron herb, 20 g of elm root bark, 20 g of lygodium japonicum, 20 g of pyrrosia lingua, 10 g of chicken's gizzard-membrane, 10 g of curcuma aromatica, 10 g of achyranthes bidentata and 10 g of agilawood.
The further scheme is that the feed is prepared from the following raw materials by weight: 120 g of longhairy antenoron herb, 40 g of elm root bark, 40 g of lygodium japonicum, 40 g of pyrrosia lingua, 20 g of chicken's gizzard-membrane, 20 g of curcuma aromatica, 20 g of achyranthes bidentata and 20 g of agilawood.
The further scheme is that the feed is prepared from the following raw materials by weight: 90 g of longhairy antenoron herb, 30 g of elm root bark, 30 g of Japanese climbing fern spore, 30 g of pyrrosia leaf, 15 g of chicken's gizzard-membrane, 15 g of turmeric root-tuber, 15 g of twotooth achyranthes root and 15 g of Chinese eaglewood.
The traditional Chinese medicine composition can be prepared into various applicable formulations such as decoction, powder, pills or capsules.
The invention has the beneficial effects that:
the traditional Chinese medicine composition can clear heat, promote urination, promote qi circulation and remove urinary calculus, is suitable for urinary calculus patients, has no adverse reaction, and has stable curative effect.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, specific embodiments thereof are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention can be embodied in many different forms than those herein described and many modifications may be made by one skilled in the art without departing from the spirit and scope of the invention.
The present invention will be further described with reference to the following embodiments.
Example 1
Taking the following raw materials by weight: 60 g of longhairy antenoron herb, 20 g of elm root bark, 20 g of lygodium japonicum, 20 g of pyrrosia lingua, 10 g of chicken's gizzard-membrane, 10 g of turmeric root-tuber, 10 g of twotooth achyranthes root and 10 g of agilawood.
Example 2
Taking the following raw materials by weight: 120 g of longhairy antenoron herb, 40 g of elm root bark, 40 g of lygodium japonicum, 40 g of pyrrosia lingua, 20 g of chicken's gizzard-membrane, 20 g of curcuma aromatica, 20 g of achyranthes bidentata and 20 g of agilawood, and the traditional Chinese medicine composition is prepared.
Example 3
Taking the following raw materials by weight: 90 g of longhairy antenoron herb, 30 g of elm root bark, 30 g of lygodium japonicum, 30 g of pyrrosia lingua, 15 g of chicken's gizzard-membrane, 15 g of curcuma aromatica, 15 g of achyranthes bidentata and 15 g of agilawood, and the traditional Chinese medicine composition is prepared.
The traditional Chinese medicine composition can be prepared into various applicable formulations such as decoction, powder, pills or capsules.
The traditional Chinese medicine composition comprises the following components:
herba Lysimachiae Christinae: sweet, salty and slightly cold. Has the effects of removing dampness and jaundice, promoting urination, treating stranguria, and removing toxic substance and swelling. Can be used for treating damp-heat jaundice, gallbladder distention, hypochondriac pain, stranguria with stone, stranguria with heat, difficulty and pain in urination, carbuncle, furuncle, and snake and insect bite. The inventor of the application finds out through research that: the polysaccharide component in the alcohol insoluble substance of herba Lysimachiae Christinae has effect in inhibiting calcium monohydrochloride crystal growth, and can relieve renal calculus.
The elm root bark is sweet and flat. Is nontoxic. Has the effects of inducing diuresis, treating stranguria and relieving swelling. Can be used for treating urinary obstruction, stranguria with turbid urine, edema, carbuncle, cellulitis, carbuncle on the back, erysipelas, and scabies.
Climbing fern spore: sweet, salty and cold in nature. Has effects of clearing away dampness and heat, treating stranguria, and relieving pain. Can be used for treating pyretic stranguria, urolithic stranguria, bloody stranguria, chylous stranguria, and urethral astringency and pain.
Shiwei is sweet, bitter and slightly cold. Enter lung and bladder meridians. Has the effects of relieving stranguria, clearing away lung-heat, and clearing away heat. It can be used for treating stranguria, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung heat, chronic tracheitis, incised wound, and superficial infection.
Endothelium corneum gigeriae galli: sweet and neutral. Has effects of invigorating stomach, resolving food stagnation, arresting seminal emission, relieving stranguria, and removing calculus. Can be used for treating dyspepsia, emesis, dysentery, infantile malnutrition, enuresis, nocturnal emission, stranguria with stone, pain, gallbladder distention, and hypochondriac pain.
Turmeric root-tuber: pungent, bitter and cold. Has effects of promoting blood circulation, relieving pain, activating qi-flowing, resolving stagnation, clearing heart fire, cooling blood, promoting bile flow, and eliminating jaundice. Can be used for treating pricking pain in chest and hypochondrium, thoracic obstruction, cardialgia, amenorrhea, dysmenorrhea, breast pain, coma due to fever, epilepsy, hematemesis, hemorrhage, jaundice, and dark urine.
Radix cyathulae: sweet, slightly bitter and neutral in nature. Has the effects of removing blood stasis, dredging channels, promoting joint movement, inducing diuresis and treating stranguria. Can be used for treating amenorrhea, abdominal mass, retained afterbirth, traumatic injury, rheumatalgia, flaccidity of feet, spasm of tendons, and hematuria.
Agilawood: pungent and bitter with slightly warm nature. Move qi and alleviate pain, warm middle energizer and arrest vomiting, receive qi and relieve dyspnea. Can be used for treating chest and abdomen distention, pain, stomach cold, emesis, singultus, deficiency of the kidney, reversed flow of qi, and dyspnea.
In the composition, the lysimachia christinae hance and the elm root bark are combined with the heat-clearing stranguria-treating medicine as the monarch medicine; spora Lygodii, folium Pyrrosiae and radix Cyathulae are combined to treat stranguria and relieve pain, and endothelium corneum Gigeriae Galli is used for treating stranguria and dissolving calculus as ministerial drugs; radix Curcumae and lignum Aquilariae Resinatum have the effects of promoting qi circulation and relieving pain. The medicines are combined to clear heat and promote diuresis, promote qi circulation and remove urinary calculus.
The traditional Chinese medicine composition can achieve the effects of clearing heat, promoting urination, promoting qi circulation and removing urinary calculus.
The traditional Chinese medicine composition has scientific and reasonable components and safe compatibility and medication, 100 cases of clinical observation data related to patients are screened and provided for showing the treatment effect of the traditional Chinese medicine composition, the 100 cases are divided into four groups according to the random distribution principle, the four groups are respectively 25 cases for treating one group, 25 cases for treating two groups, 25 cases for treating three groups and 25 cases for controlling the groups, the patients in the two groups have no statistical significance in comparison in the aspects of illness state, personal basic condition and the like, and the two groups have comparability.
Firstly, selecting a standard:
urinary stone patients can be used as the standard of choice cases.
II, diagnosis standard:
colic in the waist and abdomen, nausea, vomiting, dysphoria, abdominal distension, hematuria, etc. During the onset of pain and hematuria, sand or small stones may be excreted with the urine; if combined with urinary tract infection, aversion to cold and fever may occur. Acute renal colic often causes patients to have intolerable pain.
Third, embodiment
The treatment group is prepared into decoction by using the traditional Chinese medicine composition disclosed by the embodiment of the invention as required, the decoction is taken once in the morning and at night, 500ml is taken once each time, 1 month is taken as a treatment course, and statistics is carried out after 1 treatment course, wherein the traditional Chinese medicine composition disclosed by the embodiment 1 is used for one treatment group, the traditional Chinese medicine composition disclosed by the embodiment 2 is used for two treatment groups, and the traditional Chinese medicine composition disclosed by the embodiment 3 is used for three treatment groups.
The control group is orally administered with calculus removing granule according to the drug specification, 1 month is a treatment course, and statistics is carried out after 1 treatment course.
Fourth, comparison results
In a group of treatment, 15 patients have obvious effects, accounting for 60%, 6 patients have effects, accounting for 24%, 4 patients have no effects, accounting for 16%, and the total effective rate is 84%; in the two groups of treatment, 16 patients have obvious effects, accounting for 64 percent, 6 patients have effects accounting for 15 percent, 3 patients have no effects accounting for 11 percent, and the total effective rate is 89 percent; in three groups, 15 patients with obvious disease effects account for 60%, 7 patients with effective diseases account for 24%, 3 patients with ineffective diseases account for 11%, and the total effective rate is 89%; in the control group, 9 patients with obvious effect account for 36%, 6 patients with effective disease account for 24%, 10 patients with ineffective disease account for 40%, and the total effective rate is 60%; the effective state means that the state of the patient is controlled, and the ineffective state means ineffective symptoms and no obvious improvement.
The observation results show that the traditional Chinese medicine composition has good treatment effect on urinary calculus patients.
The traditional Chinese medicine composition is prepared into other dosage forms, the same or similar results are obtained in experiments, the listing is omitted, the description is prevented from being accumulated, and the application claims the traditional Chinese medicine composition (combination invention) rather than the dosage form or the preparation method, so that any dosage form prepared from the traditional Chinese medicine composition belongs to the protection scope of the application and medicines for treating the same diseases.
Claims (6)
1. A traditional Chinese medicine composition for treating urinary calculus is characterized in that: the feed consists of the following raw materials: herba Lysimachiae Christinae, cortex Ulmi Pumilae, spora Lygodii, folium Pyrrosiae, endothelium corneum Gigeriae Galli, radix Curcumae, Achyranthis radix, and lignum Aquilariae Resinatum.
2. The traditional Chinese medicine composition for treating urinary calculus according to claim 1, which is characterized in that: the feed is prepared from the following raw materials in parts by weight: 60-120 g of longhairy antenoron herb, 20-40 g of elm root bark, 20-40 g of lygodium japonicum, 20-40 g of pyrrosia lingua, 10-20 g of chicken's gizzard-membrane, 10-20 g of turmeric root-tuber, 10-20 g of twotooth achyranthes root and 10-20 g of agilawood.
3. The traditional Chinese medicine composition for treating urinary calculus according to claim 2, which is characterized by being prepared from the following raw materials by weight: 60 g of longhairy antenoron herb, 20 g of elm root bark, 20 g of lygodium japonicum, 20 g of pyrrosia lingua, 10 g of chicken's gizzard-membrane, 10 g of curcuma aromatica, 10 g of achyranthes bidentata and 10 g of agilawood.
4. The traditional Chinese medicine composition for treating urinary calculus according to claim 2, which is characterized by being prepared from the following raw materials by weight: 120 g of longhairy antenoron herb, 40 g of elm root bark, 40 g of lygodium japonicum, 40 g of pyrrosia lingua, 20 g of chicken's gizzard-membrane, 20 g of curcuma aromatica, 20 g of achyranthes bidentata and 20 g of agilawood.
5. The traditional Chinese medicine composition for treating urinary calculus according to claim 2, which is characterized by being prepared from the following raw materials by weight: 90 g of longhairy antenoron herb, 30 g of elm root bark, 30 g of Japanese climbing fern spore, 30 g of pyrrosia leaf, 15 g of chicken's gizzard-membrane, 15 g of turmeric root-tuber, 15 g of twotooth achyranthes root and 15 g of Chinese eaglewood.
6. The traditional Chinese medicine composition for treating urinary calculus according to any of claims 1-5, which is characterized in that: the Chinese medicinal composition is prepared into decoction, powder, pills or capsules.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202011076905.9A CN112168939A (en) | 2020-10-10 | 2020-10-10 | Traditional Chinese medicine composition for treating urinary calculus |
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| CN202011076905.9A CN112168939A (en) | 2020-10-10 | 2020-10-10 | Traditional Chinese medicine composition for treating urinary calculus |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237003A (en) * | 2016-08-31 | 2016-12-21 | 黄逢雨 | A kind of Chinese medicine composition treating kidney yang deficiency syndrome urinary system calculus |
| CN109276583A (en) * | 2017-07-21 | 2019-01-29 | 姚庆诚 | The prescription of one group for the treatment of stone in urinary system |
-
2020
- 2020-10-10 CN CN202011076905.9A patent/CN112168939A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237003A (en) * | 2016-08-31 | 2016-12-21 | 黄逢雨 | A kind of Chinese medicine composition treating kidney yang deficiency syndrome urinary system calculus |
| CN109276583A (en) * | 2017-07-21 | 2019-01-29 | 姚庆诚 | The prescription of one group for the treatment of stone in urinary system |
Non-Patent Citations (4)
| Title |
|---|
| 何光向: "四金二石汤治疗泌尿系统结石48例", 《浙江中西医结合杂志》 * |
| 张瑞麟: "石淋四则", 《广西中医药》 * |
| 朴志贤主编: "《肾脏病临床诊治》", 31 January 2006, 科学技术文献出版社 * |
| 范嵘: "中西医结合治疗泌尿系结石84例分析", 《中国误诊学杂志》 * |
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