CN112161926A - Fluorescence immunoassay appearance and reagent card cartridge guide prevent pulling out mechanism - Google Patents
Fluorescence immunoassay appearance and reagent card cartridge guide prevent pulling out mechanism Download PDFInfo
- Publication number
- CN112161926A CN112161926A CN202010890189.1A CN202010890189A CN112161926A CN 112161926 A CN112161926 A CN 112161926A CN 202010890189 A CN202010890189 A CN 202010890189A CN 112161926 A CN112161926 A CN 112161926A
- Authority
- CN
- China
- Prior art keywords
- reagent card
- roller
- unidirectional rotation
- guide roller
- elastic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
- G01N2021/0112—Apparatus in one mechanical, optical or electronic block
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention relates to a fluorescence immunoassay analyzer and a reagent card plug-in guiding anti-pulling mechanism, and belongs to the field of immunoassay instruments. The fluorescence immunoassay analyzer comprises a bracket, a reagent card inserting slot seat, an information reading head, a linear displacement output device and a reagent card inserting guiding anti-pulling mechanism, wherein the reagent card inserting slot seat, the information reading head, the linear displacement output device and the reagent card inserting guiding anti-pulling mechanism are arranged on the bracket; the reagent card inserting and guiding anti-pulling mechanism is arranged beside an inlet for inserting the reagent card into the accommodating groove and comprises a roller mounting seat, a guide roller, a unidirectional rotation locking mechanism and an unlocking mechanism; the guide roller is rotatably arranged on the roller mounting seat and is at least used for guiding the inserting action of the reagent card; the unidirectional rotation locking mechanism is used for releasably locking the unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism is used for controlling the working state of the unidirectional rotation locking mechanism so as to release the steering locking state of the guide roller. Based on the additional reagent card plug-in mounting guide anti-pulling mechanism, the risk can be effectively reduced, and the method can be widely used for rapid detection of new coronavirus and the like.
Description
Technical Field
The invention relates to the field of in-vitro diagnosis and detection instruments, in particular to a fluorescence immunoassay analyzer and a reagent card plug-in guiding anti-pulling mechanism for constructing the fluorescence immunoassay analyzer.
Background
The immunochromatography detection technology in the field of in vitro diagnosis and detection is a technology established on the basis of chromatography and antigen-antibody specific immunoreaction; at present, major immunochromatographic techniques include fluorescence immunochromatography and colloidal gold chromatography, and for example, an immunochromatographic method based on a fluorescent substance as a label is disclosed in patent document with publication number CN 1645146A; the immunochromatography rapid detection technology has the advantage of short detection time, can obtain detection analysis results even in half an hour, can be used as an instant detection technology for improving the detection speed of viruses and the like, for example, for rapid and accurate detection and analysis of novel coronaviruses, can provide a powerful detection means for prevention and control of the current epidemic situation, is commonly used in clinical sites, and belongs to site rapid biochemical/immunological detection (POCT).
As a detection apparatus that operates based on immunochromatography detection technology, for example, a fluorescence immunoassay analyzer structure disclosed in patent document No. CN2252991Y specifically includes a light source, a sample feeding mechanism, a detection and interface circuit, and the like; in order to improve the degree of automation and the detection speed of detection, a reagent card 01 shown in fig. 1 is usually used to carry a sample to be detected, and an identification code such as a two-dimensional code, a bar code and the like arranged on the reagent card can be used to facilitate an instrument to automatically identify the relevant information of the reagent card and return the detection analysis result to the storage information of the detection object; corresponding to the structure of the reagent card, the analyzer is configured as shown in fig. 2, and the sample feeding mechanism is configured to include a holder 02, a reagent card insertion slot 03 for clampingly loading the reagent card 01, and a linear displacement output device. The reagent card inserting groove seat 03 is mounted on the bracket 02 in a reciprocating manner along the X-axis direction through a guide rail sliding block mechanism 05; the mover 04 of the linear displacement output device is fixedly connected with the reagent card insertion groove seat 03, so that the reagent card insertion groove seat 03 can be driven to reciprocate along the X axial direction under the control of the controller. Meanwhile, the information reading head 07 is fixedly mounted on the support 02 by the mounting support 06. In the working process, the reagent card 01 is inserted into the accommodating slot of the reagent card insertion slot seat 03 and is held in the accommodating slot in a clamping manner, generally elastically clamped in the accommodating slot, and as the linear displacement output device 04 drives the slot seat to move forward along the X axis, when the corresponding area of the reagent card 01 moves to the target position below the information reading head 06, relevant information, including detection information, is obtained.
In addition, the mounting structure of the sample feeding and information reading head 07 on the carriage 02 may be configured such that the information reading head 06 is moved in the negative X-axis direction by the linear displacement output means, and the reagent card insertion slot block 03 for inserting the reagent card 01 is directly fixed to the carriage 02 while being kept stationary.
No matter which structure is adopted to construct the fluorescence immunoassay analyzer, the following problems exist: there is a risk that the reagent card 01 is inadvertently pulled out of the cartridge accommodating groove of the reagent card cartridge 03, and there is a risk of cross-infection and incorrect detection.
Disclosure of Invention
The invention mainly aims to provide a fluorescence immunoassay analyzer, which can effectively avoid the occurrence of card taking without attention, thereby reducing the risks of cross infection and incorrect detection;
still another object of the present invention is to provide a reagent card insertion guiding anti-pulling mechanism for constructing the fluorescence immunoassay analyzer.
In order to achieve the main purpose, the fluorescence immunoassay analyzer provided by the invention comprises a bracket, a reagent card insertion slot seat, an information reading head, a linear displacement output device and a reagent card insertion guiding anti-pulling mechanism, wherein the reagent card insertion slot seat, the information reading head, the linear displacement output device and the reagent card insertion guiding anti-pulling mechanism are arranged on the bracket; the reagent card insertion groove seat is used for clamping a reagent card inserted in the accommodating groove of the reagent card insertion groove seat, and the linear displacement output device is used for driving the reagent card insertion groove seat and the information reading head to move relatively; the reagent card inserting and guiding anti-pulling mechanism is arranged beside an inlet for inserting the reagent card into the accommodating groove and comprises a roller mounting seat, a guide roller, a unidirectional rotation locking mechanism and an unlocking mechanism; the guide roller is rotatably arranged on the roller mounting seat and is at least used for guiding the inserting action of the reagent card; the unidirectional rotation locking mechanism is used for releasably locking the unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism is used for controlling the working state of the unidirectional rotation locking mechanism so as to release the steering locking state of the guide roller; the guide roller is an elastic extrusion roller with a roller surface being a friction damping surface, and is used for providing surface extrusion force for the reagent card pressed on the guide roller and simultaneously providing locking anti-pulling friction force when the reagent card and the elastic extrusion roller slide relatively.
In the technical scheme, the reagent card insertion guiding anti-pulling mechanism is additionally arranged at the reagent card insertion opening, so that the guiding roller which can only rotate along the card insertion direction provides anti-pulling friction force for the reagent card pulled out along the card insertion direction under the steering locking state, the risk of inadvertently pulling out the reagent card from the insertion accommodating groove of the reagent card insertion groove seat can be effectively prevented, and the risk of cross infection and incorrect detection is reduced. And after the detection is finished, the unlocking mechanism is controlled to work when the reagent card needs to be pulled out, and the steering locking state of the guiding roller by the unidirectional rotation locking mechanism is unlocked, so that the reagent card cannot be prevented from being pulled out.
The one-way rotation locking mechanism includes a lock reset mechanism for resetting the one-way rotation locking mechanism to a steering lock state after the unlocking mechanism releases a lock release control of the one-way rotation locking mechanism. The technical scheme can automatically reset the locking state to avoid the state that the locking is not reset.
The more concrete scheme is that the unidirectional rotation locking mechanism is a ratchet mechanism, a ratchet wheel of the unidirectional rotation locking mechanism is fixed on the end part of the guide roller, and a pawl of the unidirectional rotation locking mechanism is fixed on the roller mounting seat; the release mechanism is used to decouple the pawl from the ratchet. The ratchet mechanism is adopted to construct the unidirectional rotation locking mechanism, so that the integral structure can be effectively simplified.
The further proposal is that the pawl is a reed with one end fixed on the roller mounting seat; the unlocking mechanism is an electromagnet and is used for magnetically attracting the free end part of the reed when the unlocking mechanism is electrified so as to enable the free end part to be decoupled from the ratchet wheel; the lock reset mechanism comprises a reed. The pawl is constructed by using the spring pieces, so that the integral structure can be further simplified.
The further proposal is that the guide roller comprises a supporting mandrel which is rotatably arranged on the roller mounting seat and an elastic roller which is fixedly sleeved outside the supporting mandrel; the ratchet wheel is fixed on the end part of the support mandrel. The guide roller which has supporting strength and can provide elastic force is convenient to manufacture.
The more specific proposal is that the unidirectional rotation locking mechanism is a unidirectional clutch mechanism; the one-way clutch mechanism comprises a driven part fixedly connected with the roller mounting seat, a driving part fixedly connected with the elastic extrusion roller and an elastic pressing mechanism; the elastic restoring force of the elastic pressing mechanism is used for forcing the clutch driven part to be in one-way transmission engagement with the clutch driving part; the unlocking mechanism is a clutch operating mechanism and is used for forcing the clutch driven part to overcome the elastic restoring force of the elastic pressing mechanism so as to enable the clutch driven part to be disengaged from the driving part.
The guide roller comprises a support mandrel and an elastic roller which can be rotatably sleeved outside the support mandrel; the driving part is a first sawtooth groove group which is concavely formed on the end surface of the elastic roller; the first zigzag groove group comprises a plurality of zigzag grooves which are continuously arranged in a circle around the circumference of the support mandrel; in the first zigzag groove group, each zigzag groove comprises a first oblique leading-in and leading-out surface part positioned on the upstream side, a first axial locking surface part positioned on the downstream side and a first transition surface part used for connecting the first oblique leading-in and leading-out surface part and the first axial locking surface part along the reverse direction of the inserting card; the unidirectional rotation locking mechanism comprises a stop chuck fixed on the external connection end part and a sliding sleeve which can rotate and is sleeved outside the support core shaft in an axially sliding manner; the driven part is a second zigzag groove group which is concavely formed on the end surface of the sliding sleeve, and the second zigzag groove group is meshed with the first zigzag groove group; the elastic pressing mechanism is a torsion spring sleeved outside the support core shaft; the sliding sleeve is positioned between the first zigzag groove group and the stop chuck; the spring ring of the torsion spring is pressed between the sliding sleeve and the stopping chuck, and the compressible stroke is greater than the meshing depth of the two groups of sawtooth-shaped grooves; one torsion arm of the torsion spring is coupled on the stopping chuck, and the other torsion arm is coupled on the sliding sleeve; the unlocking mechanism comprises a driving mechanism and a driving mechanism, wherein the driving mechanism is used for driving the sliding sleeve to overcome the elastic thrust of the spring coil so as to enable the second sawtooth-shaped groove to be decoupled from the first sawtooth-shaped groove; the lock return mechanism includes a torsion spring.
The preferable scheme is that a clamping block pressed on the reagent card is arranged on one side of the reagent card, which is far away from the guide roller, and is used for forcing the reagent card to be clamped and pressed on the guide roller.
More preferably, the pressing block is fixedly arranged on the reagent card inserting groove seat or the pressing block is fixedly arranged on the roller mounting seat.
The preferred solution is that the guiding rollers are supporting rollers for supporting the reagent card by pressing from the bottom side.
The preferred scheme is that the reagent card inserting slot seat is fixed on the bracket, the information reading head is movably arranged on the bracket, and the reagent card inserting guiding anti-pulling mechanism is fixed on the reagent card inserting slot seat.
The preferred scheme is that the information reading head is fixed on a bracket, the reagent card inserting slot seat is slidably arranged on the bracket through a guide rail, and the reagent card inserting guiding anti-pulling mechanism is fixed on the bracket or the guide rail.
In order to achieve the other purpose, the reagent card insertion guiding anti-pulling mechanism provided by the invention is arranged beside the reagent card insertion inlet and specifically comprises a roller mounting seat, a guide roller, a unidirectional rotation locking mechanism, a pressing block and an unlocking mechanism; the guide roller is rotatably arranged on the roller mounting seat and is at least used for guiding the inserting action of the reagent card; the unidirectional rotation locking mechanism is used for releasably locking the unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism is used for controlling the working state of the unidirectional rotation locking mechanism so as to release the steering locking state of the guide roller; the pressing block is used for forcing the reagent card between the pressing block and the guide roller to be elastically pressed on the guide roller; the roller surface of the guide roller is a friction damping surface and is used for providing surface extrusion force for the reagent card pressed on the roller surface and simultaneously providing anti-pulling friction force when the reagent card and the guide roller slide relatively.
The specific scheme is that the pressing block is a rigid block structure with a fixed position, and the guide roller is an elastic extrusion roller.
Preferably, the unidirectional rotation locking mechanism includes a lock return mechanism for returning the unidirectional rotation locking mechanism to the steering lock state after the unlocking mechanism releases the lock release control of the unidirectional rotation locking mechanism.
The further proposal is that the unidirectional rotation locking mechanism is a ratchet mechanism, a ratchet wheel of the unidirectional rotation locking mechanism is fixed on the end part of the guide roller, and a pawl of the unidirectional rotation locking mechanism is fixed on the roller mounting seat; the release mechanism is used to decouple the pawl from the ratchet.
A further proposal is that the pawl is a reed with one end fixed on the roller mounting seat; the unlocking mechanism is an electromagnet and is used for magnetically attracting the free end part of the reed when the unlocking mechanism is electrified so as to enable the free end part to be decoupled from the ratchet wheel; the lock reset mechanism comprises a reed.
A further proposal is that the guide roller comprises a supporting mandrel which is rotatably arranged on the roller mounting seat, and an elastic roller which is fixedly sleeved outside the supporting mandrel.
The more specific proposal is that the unidirectional rotation locking mechanism is a unidirectional clutch mechanism; the one-way clutch mechanism comprises a driven part fixedly connected with the roller mounting seat, a driving part fixedly connected with the elastic extrusion roller and an elastic pressing mechanism; the elastic restoring force of the elastic pressing mechanism is used for forcing the clutch driven part to be in one-way transmission engagement with the clutch driving part; the unlocking mechanism is a clutch operating mechanism and is used for forcing the clutch driven part to overcome the elastic restoring force of the elastic pressing mechanism so as to enable the clutch driven part to be disengaged from the driving part.
The guide roller comprises a support mandrel and an elastic roller which can be rotatably sleeved outside the support mandrel; the driving part is a first sawtooth groove group which is concavely formed on the end surface of the elastic roller; the first zigzag groove group comprises a plurality of zigzag grooves which are continuously arranged in a circle around the circumference of the support mandrel; in the first zigzag groove group, each zigzag groove comprises a first oblique leading-in and leading-out surface part positioned on the upstream side, a first axial locking surface part positioned on the downstream side and a first transition surface part used for connecting the first oblique leading-in and leading-out surface part and the first axial locking surface part along the reverse direction of the inserting card; the unidirectional rotation locking mechanism comprises a stop chuck fixed on the external connection end part and a sliding sleeve which can rotate and is sleeved outside the support core shaft in an axially sliding manner; the driven part is a second zigzag groove group which is concavely formed on the end surface of the sliding sleeve, and the second zigzag groove group is meshed with the first zigzag groove group; the elastic pressing mechanism is a torsion spring sleeved outside the support core shaft; the sliding sleeve is positioned between the first zigzag groove group and the stop chuck; the spring ring of the torsion spring is pressed between the sliding sleeve and the stopping chuck, and the compressible stroke is greater than the meshing depth of the two groups of sawtooth-shaped grooves; one torsion arm of the torsion spring is coupled on the stopping chuck, and the other torsion arm is coupled on the sliding sleeve; the unlocking mechanism comprises a driving mechanism and a driving mechanism, wherein the driving mechanism is used for driving the sliding sleeve to overcome the elastic thrust of the spring coil so as to enable the second sawtooth-shaped groove to be decoupled from the first sawtooth-shaped groove; the lock return mechanism includes a torsion spring.
Drawings
FIG. 1 is a schematic diagram of a conventional reagent card;
FIG. 2 is a schematic view of a conventional fluorescence immunoassay analyzer;
FIG. 3 is a perspective view showing the structure of a fluorescence immunoassay analyzer according to example 1 of the present invention;
FIG. 4 is a front view showing the structure of a fluorescence immunoassay analyzer according to example 1 of the present invention;
FIG. 5 is a partial view showing the construction of the fluorescence immunoassay analyzer at the inlet of the reagent card cartridge in example 1 of the present invention;
FIG. 6 is an enlarged view of a portion A of FIG. 5;
FIG. 7 is a partial structural view of a fluorescence immunoassay analyzer in example 1 of the present invention at a reagent card insertion port from a view different from that shown in FIG. 5;
FIG. 8 is an enlarged view of a portion B of FIG. 7;
FIG. 9 is an exploded view of the guide roller and the unidirectional rotation locking mechanism in embodiment 1 of the present invention;
FIG. 10 is an enlarged partial end view of the structure of FIG. 9;
FIG. 11 is a schematic structural view of the first zigzag groove set and the second zigzag groove set engaged with each other in example 1 of the present invention;
FIG. 12 is a schematic structural view of the first zigzag groove set and the second zigzag groove set completely decoupled in example 1 of the present invention;
FIG. 13 is a partial view showing the configuration of a fluorescence immunoassay analyzer at a reagent card insertion port in example 2 of the present invention;
FIG. 14 is an enlarged view of portion C of FIG. 13;
FIG. 15 is a partial exploded view of a fluorescence immunoassay analyzer at a reagent card insertion inlet in example 3 of the present invention;
FIG. 16 is a first state diagram in which the unidirectional rotation lock mechanism urges the unidirectional rotation of the guide roller in embodiment 3 of the present invention;
FIG. 17 is a second state diagram in which the unidirectional rotation lock mechanism urges the unidirectional rotation of the guide roller in embodiment 3 of the present invention;
fig. 18 is a structural view of a reagent card insertion slot in the embodiment of the present invention.
Detailed Description
The invention is further illustrated by the following examples and figures.
The invention mainly aims to improve the local structure of the existing fluorescence immunoassay analyzer, and particularly relates to a reagent card insertion guiding anti-pulling mechanism which is additionally arranged beside an inlet for inserting a reagent card so as to avoid the card taking without attention in the test process, thereby reducing the risks of cross infection and incorrect detection. In addition, functional units other than the main invention point of the present invention, such as a heating unit, can be arranged or added according to actual needs for heating the reagent card inserted in the reagent card slot seat; or for example, the reagent card in-place detection unit is used for detecting whether the reagent card is positioned at a target position, for example, the reagent card is inserted in the reagent card slot seat in-place for detection, and the in-place detection sensor can be constructed by adopting a photoelectric sensor, a contact type trigger switch and the like; the addition or arrangement of the structure beyond the invention point of the aforementioned main concept can be arranged by referring to the existing product.
Example 1
Referring to fig. 3 to 12, the fluorescence immunoassay analyzer 1 of the present invention includes a rack 10, a reagent card insertion slot 2 mounted on the rack 10, an information reading head 11, a linear displacement output device 3, and a reagent card insertion guide anti-pulling mechanism 4. The reagent card insertion well 2 is located below the information reading head 11. The support 10 comprises a bottom mounting plate 100 and a vertical mounting plate 101 which are connected into an integral structure, wherein the two are arranged into an L-shaped cross section; the information reading head 11 is fixed to the vertical mounting plate 101 by a connecting frame 102, and the reagent card insertion slot holder 2 is mounted to the rack 10 so as to be capable of reciprocating sliding in the X-axis direction by a guide rail 51 and a guide rail 52.
Referring to fig. 18, the reagent card cartridge 2 includes a cartridge body portion 20 and a connection end portion 21 for connection with the linear displacement output device 3; a housing groove 200 having an open upper side defined by the bottom wall plate portion 21, the side wall plate portion 22, and the side wall plate portion 23 in the groove body portion 20, so that the reagent card 01 is confined in the housing groove 200 in the Y-axis direction; a plurality of holding pieces 220 are formed on the upper end of the side wall plate part 22 extending inward in the lateral direction, and a plurality of holding pieces 230 are formed on the upper end of the side wall plate part 23 extending inward in the lateral direction, so that the reagent card 01 can be confined in the accommodation groove 200 thereof in the Z-axis direction; an obliquely arranged introduction surface 221 is formed on the front end side of the pressing block 220, and an obliquely arranged introduction surface is formed on the front end side of the pressing block 230; at the entrance of the housing groove 200, the leading end of the inner wall surface of the bottom wall plate 21 is formed with an obliquely arranged introduction surface 210, the leading end of the inner wall surface of the side wall plate 22 is formed with an obliquely arranged introduction surface 222, and the leading end of the inner wall surface of the side wall plate 23 is formed with an obliquely arranged introduction surface.
In operation, reagent card 01 as shown in FIG. 1 is inserted into receiving slot 200 in the positive X-axis direction, i.e., the positive X-axis direction constitutes the insertion direction in this embodiment and the negative X-axis direction constitutes the insertion direction in this embodiment.
The guide rail 51 and the guide rail 52 are both of a T-shaped structure in cross section and are fixed on the bottom mounting plate 100, so that the slide groove 50 with a convex-shaped structure in cross section is formed by enclosing the upper plate surface of the bottom mounting plate 100, the freedom degree of the reagent card insertion slot seat 2 is limited in the Y-axis direction and the Z-axis direction, and the slot length direction of the slide groove 50 is arranged along the X-axis direction, so that the reagent card insertion slot seat 2 can be sleeved in the slide groove 50 in a reciprocating manner along the X-axis direction.
The linear displacement output device 3 comprises a servo motor 30, a synchronous pulley 31, a synchronous pulley 32, a synchronous pulley 33, a synchronous belt 34, a tension pulley 35 and a connecting head 36 fixedly connected on the synchronous belt 34, wherein the connecting head 36 is fixedly connected with the connecting end part 21, the servo motor 30 is fixed on the vertical mounting plate 101, and the synchronous pulley 31, the synchronous pulley 32, the synchronous pulley 33, the synchronous belt 34 and the tension pulley 35 are all rotatably mounted on the vertical mounting plate 101; the tension pulley 35 abuts against the outer belt surface of the synchronous belt 34 to adjust the tension of the synchronous belt 34; the servo motor 30 is used for driving the synchronous pulleys 31 to rotate forwards and backwards, so as to drive the synchronous belt 34 engaged outside the three synchronous pulleys, so as to drive the connecting head 36 to advance or retreat along the X-axis, so as to drive the reagent card inserting groove seat 2 to reciprocate along the X-axis in the sliding groove 50. That is, during operation, the linear displacement output device 3 is used to drive the information reading head 11 and the reagent card insertion slot 2 to move along the direction X.
That is, in the present embodiment, the reagent card insertion slot seat 2 is provided with a receiving slot 200 extending along the card insertion direction, and the receiving slot 200 is used for elastically holding the reagent card 01 inserted therein; specifically, can lay elastic structure on bottom wall plate 21, lateral wall plate 22 and lateral wall plate 23, cooperate with compact heap 220 and compact heap 230 to inject reagent card 01 in holding tank 200, and can not appear rocking in the Z axial with the Y axial.
As shown in fig. 4 to 12, the reagent card insertion guide pulling-prevention mechanism 4 includes a guide roller 40, a unidirectional rotation locking mechanism 6, a roller mounting seat and an unlocking mechanism 41; a through hole 519 for the guide roller 40 to pass through is provided on the guide rail 51, and a through hole 529 for the guide roller 40 to pass through is provided on each of the guide rails 52, so that the guide roller 40 is arranged in the Y-axis direction in the axial direction, and the guide roller 40 is arranged on the side of the inlet for inserting the reagent card 01 into the housing groove 200; roller mounts for supporting and mounting both end portions of the guide roller 40 are disposed in the through- holes 519 and 529. The guide roller 40 includes a support core shaft 42 fixedly mounted on the roller mounting seat, and an elastic roller 43 rotatably fitted around the support core shaft 42. Wherein the elastic roller 43 is made of elastic rubber, and the outer surface is processed into a rough surface structure to improve the friction force against objects pressed on the surface; the support mandrel 42 is made of a metal material or a hard plastic, preferably steel, and is provided on the outer wall surface thereof with a plurality of grooves 420 extending in the axial direction thereof, so that the friction between the elastic roller 43 and the same can be reduced to facilitate the relative rotation of the elastic roller 43 with respect to the support mandrel 42.
The unidirectional rotation locking mechanism 6 includes a stop chuck 60 fixed on the external connection end of the support spindle 42, a sliding sleeve 61 rotatably and axially slidably sleeved on the outside of the support spindle 42, and a torsion spring 62 sleeved on the outside of the support spindle 42. The end of the resilient roller 43 adjacent the stop chuck 60 is concavely or convexly formed with a first set of saw-tooth grooves 430. In the present embodiment, the first zigzag groove group 430 includes a plurality of zigzag grooves 431 arranged in a circle and continuously around the circumference of the support mandrel 42; in the first zigzag groove group 430, in the opposite direction of the aforementioned insertion card, that is, in the negative direction of the X axis, each of the zigzag grooves 431 includes a first obliquely leading-in and leading-out surface portion 433 on the upstream side, a first axially locking surface portion 432 on the downstream side, and a first transition surface portion 434 for connecting the two; in the present embodiment, the first transition surface portion 434 is a flat end portion parallel to the XOZ plane, and is a rounded surface portion where the two surface portions are connected.
The sliding sleeve 61 is positioned between the first zigzag groove group 430 and the stop chuck 60, and a second zigzag groove group 610 meshed with the first zigzag groove group 430 is formed at the end part facing the first zigzag groove group 430; correspondingly, the first zigzag groove group 430 includes a plurality of zigzag grooves 611 arranged in a circle and in succession around the circumference of the support mandrel 42; in the second zigzag groove group 610, in the aforementioned card insertion forward direction, that is, in the X-axis forward direction, each zigzag groove 611 includes a second axial locking surface portion 612 on the upstream side, a second oblique leading-in leading-out surface portion 613 on the downstream side, and a second transition surface portion 614 for connecting the two; the second transition face 614 is a flat end parallel to the XOZ plane and is a rounded face where the two faces meet.
The spring coil 620 of the torsion spring 62 is pressed between the sliding sleeve 61 and the stop chuck 60, and the compressible stroke of the spring coil 620 is greater than the meshing depth of the two groups of sawtooth-shaped grooves, namely, under the action of the elastic restoring force of the spring coil 620 arranged along the Y-axis, the first sawtooth-shaped groove group 430 is completely meshed with the second sawtooth-shaped groove group 610, and when the sliding sleeve 61 is pushed to move forwards along the Y-axis to completely separate the first sawtooth-shaped groove group 430 from the second sawtooth-shaped groove group 610, the spring coil 620 still has the compressible stroke; the stop chuck 60 is provided with a slot 600 arranged along the radial direction, four stop arms 618 are convexly formed on the peripheral surface of the sliding sleeve 61, and the included angle between every two adjacent stop arms 618 is 90 degrees; one torque arm 621 of the torsion spring 62 is coupled to the stop chuck, specifically, the torque arm 621 is sleeved in the card slot 600, the other torque arm 622 is coupled to the sliding sleeve 61, specifically, the torque arm 622 is clamped on the two stop arms 618, the elastic torque force thereof is used for forcing the sliding sleeve 61 to be fixed to the roller mounting seat in the circumferential direction, and the elastic torque force has a small range of swing, so that the jerking feeling is reduced when the reagent card is inserted and pulled out.
The unlocking mechanism 41 is a paddle hinged to the guide rail 52 by a hinge shaft 44 and abuts against the side of one of the catch arms 618 adjacent to the guide rail 52, so that during operation the free end of the paddle is pulled away from the guide rail 52 to push the catch arm 618 and thereby drive the second set 610 of saw-tooth slots out of coupling with the first set 430 of saw-tooth slots.
In the working process, when the linear displacement output device 3 drives the reagent card inserting groove seat 2 to be at the position shown in fig. 7, the reagent card 01 can be inserted into the accommodating groove 200 from the notch of the chute 50, and the unlocking mechanism 41 is not pulled by external force; at this time, the torsion spring 62 is at the maximum extensible amount, and the sliding sleeve 61 makes the first zigzag groove group 430 completely meshed with the second zigzag groove group 610 under the action of the axial elastic restoring force of the torsion spring 62, and the structure is shown in fig. 11; when a reagent card 01 needs to be inserted into the accommodating groove 200, the upper surface of the reagent card is pressed by the pressing block 220 and the pressing block 230, so that the lower surface of the reagent card is pressed on the outer peripheral surface of the elastic roller 43 to generate elastic deformation, and the friction force of the lower surface of the reagent card forces the guide roller 40 to rotate along the card inserting direction, namely the tangential speed of the contact point position is arranged along the card inserting direction; under the action of the torsional elastic restoring force of the torsion spring 62, the first oblique leading-in and leading-out surface portion 433 and the second oblique leading-in and leading-out surface portion 613 abut against each other to generate deviation, and along with the insertion action of the reagent card 01, the spring coil 620 is compressed to enable the two groups of sawtooth-shaped groove groups to be decoupled in the axial direction, so that the insertion action of the reagent card 01 can be continuously completed, and the structure is shown in fig. 12. After the reagent card 01 is inserted, the sliding sleeve 61 is no longer continuously acted by the elastic roller 43, and the first zigzag groove set 430 and the second zigzag groove set 610 are completely meshed again under the elastic force of the spring coil 620. If a pulling force in the negative X-axis direction is inadvertently applied to the reagent card 01, the first axial locking surface portion 432 and the second axial locking surface portion 612 abut against each other under the torsional elastic restoring force of the torsion spring 62, so that the sliding sleeve 61 and the elastic roller 43 are engaged and cannot rotate relatively. That is, in the present embodiment, the unidirectional rotation locking mechanism 6 is a one-way clutch mechanism, the torsion spring 62 constitutes an elastic pressing mechanism of the one-way clutch mechanism, the first zigzag groove group 430 is a clutch driving part of the one-way clutch mechanism, and the second zigzag groove group 610 is a clutch driven part of the one-way clutch mechanism. The unlocking mechanism 41 constitutes a clutch operating mechanism to drive the clutch driven part to overcome the elastic restoring force of the elastic pressing mechanism to force the clutch driving part to be disengaged from the clutch driven part. The elastic pressing mechanism functionally constitutes a lock return mechanism of the unidirectional rotation locking mechanism for returning the unidirectional rotation locking mechanism 6 to the steering lock state after the unlocking mechanism 41 releases the lock release control of the unidirectional rotation locking mechanism 6.
When the card is required to be pulled out, the shifting sheet is only needed to be shifted to enable the sliding sleeve 61 to be decoupled from the elastic roller 43, at the moment, the one-way clutch is operated to be disengaged, so that the elastic roller 43 can continuously rotate reversely towards the card insertion, and the reagent card 01 can be normally pulled out.
According to the working process, the guide roller is used for guiding the insertion action and the extraction action of the reagent card; the unidirectional rotation locking mechanism 6 is used for releasably locking the unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism 41 is used to control the operating state of the one-way rotation locking mechanism to release the steering lock state of the guide roller. The guide roller 40 is an elastic squeeze roller whose roller surface is a friction damping surface, and is used for providing surface squeezing force for the reagent card 01 pressed on the guide roller and providing anti-pulling friction force when the reagent card and the elastic squeeze roller slide relatively.
Example 2
As an explanation of embodiment 2 of the present invention, only differences from embodiment 1 will be explained below.
Referring to fig. 13 and 14, in the unlocking process in embodiment 1, the dial plate needs to be manually shifted to unlock, and two hands are usually needed to perform card pulling operation; in the embodiment, the electromagnet 91 is arranged on the bottom mounting plate 100 to magnetically attract the armature fixed on the unlocking mechanism 41, so as to complete the unlocking action, and thus the reagent card 01 can be pulled out by one hand.
Example 3
As an explanation of embodiment 3 of the present invention, only differences from embodiment 1 will be explained below.
Referring to fig. 15 to 17, in the present embodiment, the guide roller 40 includes a support core shaft 42 rotatably mounted on the roller mounting seat 83, and an elastic roller 43 fixedly fitted around the support core shaft 42; in the present embodiment, the support spindle 42 is rotatably mounted on the bottom mounting plate 100 by the rotation support slot seat 85 and the rotation support slot seat 86; the unidirectional rotation locking mechanism 6 is a ratchet mechanism, a ratchet 81 of the unidirectional rotation locking mechanism is fixed on the end part of the guide roller 40, and a pawl 82 of the unidirectional rotation locking mechanism is fixed on a first roller mounting seat 83; in the present embodiment, the ratchet 81 is fixed on the end of the support spindle 42; the unlocking mechanism 41 is used for decoupling the pawl 82 from the ratchet 81, and in the present embodiment, the pawl 82 is a spring plate with one end fixed on the first roller mounting seat 83; the unlocking mechanism 41 is an electromagnet, and magnetically attracts the free end of the reed when the power is turned on, so that the free end is decoupled from the ratchet 81. In the working process, if the electromagnet does not magnetically attract the pawl 82, the pawl 82 which is a reed is clamped in the tooth groove of the ratchet 81 under the action of the elastic restoring force of the pawl 82, so that the guide roller 40 can only rotate in one direction, the unidirectional rotation locking is realized, and the accidental pulling operation cannot be carried out; when the card-pulling operation is required, the electromagnet is energized to disengage the pawl 82 from the ratchet 81, so that the card-pulling operation can be performed by the bidirectional rotation. That is, in the present embodiment, the aforementioned spring plate constitutes the lock return mechanism in the present embodiment. In the present embodiment, the first roller mounting seat 83 is a partial structure on the bottom mounting plate 100 or a mounting seat structure fixed on the bottom mounting plate 100, and the first roller mounting seat 83, the rotation support socket 85 and the rotation support socket 86 together constitute the roller mounting seat in the present embodiment.
Example 4
As an explanation of embodiment 4 of the present invention, only differences from embodiment 1 will be explained below.
In this embodiment, the reagent card insertion slot is fixed on the bracket, and the information reading head is movably mounted on the bracket; at this time, the reagent card insertion guide pull-out prevention mechanism is fixed to the reagent card insertion groove seat or the holder.
As for the "elastic pressing roller" in the above embodiment, it is configured to be capable of generating a certain reverse elastic force in the radial direction when being pressed; the "roller" is a structure of a rotating body that is interpreted according to the existing semantics as being capable of providing guidance, and in this embodiment, if the unidirectional rotation locking mechanism is not unlocked, it can only rotate in the direction of insertion of the reagent card, and is locked in the reverse direction of the insertion card, i.e., the direction of the surface velocity at its circumferential surface in contact with the reagent card can only be arranged in the direction of insertion of the card.
For realizing the anti-pulling operation of the reagent card, the reagent card can be prevented from continuously rotating towards the plug-in card in a reverse direction for a plurality of circles, so that an operator can be reminded that the pulling-out is wrong; preferably the rotation is not more than a full revolution; it is further preferred that the rotation is less than a predetermined small degree of rotation, for example less than 90 degrees, 45 degrees, 30 degrees, or that no reverse rotation of the paddle card can occur; the aim is that the pull-out length does not exceed the normally detected position offset. The understanding of the "operation of preventing the reagent card from being pulled out" of the present invention is to prevent or remind the operator that the pulling-out of the reagent card is not performed properly, and in the case where the reagent card has been pulled out in the above embodiments or modifications, the operator can still pull out the reagent card with a strong force, and the reagent card is not locked completely.
For the reagent card insertion guiding anti-pulling mechanism, the reagent card insertion guiding anti-pulling mechanism can be constructed by adopting the one-way clutch mechanism with the structure, and can also be constructed by adopting the matching of the one-way deep groove ball bearing and a gear set, the gear set can be inserted and pulled out and separated along the axial direction of the elastic roller, and the driving gear and the elastic roller or the driven gear and the roller are arranged and are connected in a one-way rotating manner through the one-way deep groove ball bearing, so that when the driving gear and the driven gear are meshed, the elastic roller and the roller mounting seat can rotate along the card insertion direction under the action of the one-way deep groove ball bearing at the.
In the above embodiments, the guide roller provides a supporting force from the bottom layer, so as to form a pull-out preventing friction force between the contact surfaces, and the application of the pull-out preventing friction force can also be applied to the side surface or the top surface of the reagent card.
Claims (14)
1. A fluorescence immunoassay analyzer comprises a bracket, a reagent card inserting slot seat, an information reading head and a linear displacement output device, wherein the reagent card inserting slot seat, the information reading head and the linear displacement output device are installed on the bracket; the reagent card insertion groove seat is used for clamping a reagent card inserted in the accommodating groove of the reagent card insertion groove seat, and the linear displacement output device is used for driving the reagent card insertion groove seat and the information reading head to move relatively; the method is characterized in that:
the fluorescence immunoassay analyzer comprises a reagent card insertion guiding anti-pulling mechanism which is arranged beside an inlet for inserting a reagent card into the accommodating groove; the reagent card insertion guiding anti-pulling mechanism comprises a roller mounting seat, a guide roller, a unidirectional rotation locking mechanism and an unlocking mechanism; the guide roller is rotatably arranged on the roller mounting seat and is at least used for guiding the inserting action of the reagent card; the unidirectional rotation locking mechanism is used for releasably locking unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism is used for controlling the working state of the unidirectional rotation locking mechanism so as to release the steering locking state of the guide roller;
the guide roller is an elastic extrusion roller with a roller surface being a friction damping surface, and is used for providing surface extrusion force for the reagent card pressed on the guide roller and simultaneously providing anti-pulling friction force when the reagent card and the elastic extrusion roller slide relatively.
2. The fluoroimmunoassay analyzer of claim 1, wherein:
the unidirectional rotation locking mechanism includes a lock reset mechanism for resetting the unidirectional rotation locking mechanism to the steering lock state after the unlocking mechanism releases the lock release control of the unidirectional rotation locking mechanism.
3. The fluoroimmunoassay analyzer of claim 2, wherein:
the unidirectional rotation locking mechanism is a ratchet mechanism, a ratchet wheel of the unidirectional rotation locking mechanism is fixed on the end part of the guide roller, and a pawl of the unidirectional rotation locking mechanism is fixed on the roller mounting seat; the unlocking mechanism is used for decoupling the pawl from the ratchet wheel.
4. The fluoroimmunoassay analyzer of claim 3, wherein:
the pawl is a reed with one end fixed on the roller mounting seat; the unlocking mechanism is an electromagnet and is used for magnetically attracting the free end part of the reed when the unlocking mechanism is electrified so as to enable the free end part to be decoupled from the ratchet wheel;
the guide roller comprises a support mandrel which is rotatably arranged on the roller mounting seat, and an elastic roller which is fixedly sleeved outside the support mandrel; the ratchet wheel is fixed on the end part of the support mandrel;
the lock reset mechanism comprises the reed.
5. The fluoroimmunoassay analyzer of claim 2, wherein:
the unidirectional rotation locking mechanism is a unidirectional clutch mechanism; the one-way clutch mechanism comprises a driven part fixedly connected with the roller mounting seat, a driving part fixedly connected with the elastic extrusion roller and an elastic pressing mechanism; the elastic restoring force of the elastic pressing mechanism is used for forcing the driven part to be in one-way transmission engagement with the driving part; the unlocking mechanism is a clutch operating mechanism and is used for forcing the driven part to overcome the elastic restoring force and disengage from the driving part.
6. The fluoroimmunoassay analyzer of claim 5, wherein:
the guide roller comprises a support mandrel fixed on the roller mounting seat and an elastic roller rotatably sleeved outside the support mandrel; the driving part is a first sawtooth groove group which is concavely formed on the end surface of the elastic roller; the first zigzag groove group comprises a plurality of zigzag grooves which are continuously arranged in a circle around the circumference of the support mandrel; in the first zigzag slot group, each zigzag slot comprises a first oblique leading-in and leading-out surface part positioned on the upstream side, a first axial locking surface part positioned on the downstream side and a first transition surface part used for connecting the first oblique leading-in and leading-out surface part and the first axial locking surface part in the opposite direction of the plug-in card;
the unidirectional rotation locking mechanism comprises a stop chuck fixed on the external connection end part of the support mandrel and a sliding sleeve which can rotate and is sleeved outside the support mandrel in an axially sliding manner; the driven part is a second zigzag groove group which is concavely formed on the end surface of the sliding sleeve, and the second zigzag groove group is meshed with the first zigzag groove group; the elastic pressing mechanism is a torsion spring sleeved outside the support core shaft; the sliding sleeve is positioned between the first zigzag groove group and the stop chuck; the spring ring of the torsion spring is pressed between the sliding sleeve and the stopping chuck, and the compressible stroke is greater than the meshing depth of the two groups of sawtooth-shaped grooves; one torsion arm of the torsion spring is coupled to the stop chuck, and the other torsion arm of the torsion spring is coupled to the sliding sleeve;
the unlocking mechanism comprises a driving mechanism and a driving mechanism, wherein the driving mechanism is used for driving the sliding sleeve to overcome the elastic thrust of the spring coil so as to enable the second zigzag groove group to be decoupled from the first zigzag groove group;
the locking reset mechanism comprises the torsion spring.
7. The fluoroimmunoassay analyzer of any one of claims 1 to 6, wherein:
one side of the reagent card, which is far away from the guide roller, is provided with a pressing block pressed on the reagent card, and the pressing block is used for forcing the reagent card to be pressed on the guide roller;
the guide roller is a support roller and is used for supporting the reagent card by pressing from the bottom side;
the reagent card insertion guiding anti-pulling mechanism is fixed on the reagent card insertion slot seat, and the pressing block is fixedly arranged on the reagent card insertion slot seat; or the information reading head is fixed on the bracket, the reagent card inserting groove seat is slidably arranged on the bracket through a guide rail, the reagent card inserting guiding anti-pulling mechanism is fixed on the bracket or the guide rail, and the pressing block is fixedly arranged on the roller mounting seat.
8. A reagent card insertion guiding anti-pulling mechanism is used for being arranged beside a reagent card insertion inlet and is characterized by comprising a roller mounting seat, a guiding roller, a unidirectional rotation locking mechanism, a pressing block and an unlocking mechanism;
the guide roller is rotatably arranged on the roller mounting seat and is at least used for guiding the inserting action of the reagent card; the unidirectional rotation locking mechanism is used for releasably locking unidirectional rotation of the guide roller towards the card insertion direction; the unlocking mechanism is used for controlling the working state of the unidirectional rotation locking mechanism so as to release the steering locking state of the guide roller; the compressing block is used for forcing the reagent card between the compressing block and the guide roller to be elastically compressed on the guide roller;
the roller surface of the guide roller is a friction damping surface and is used for providing surface extrusion force for the reagent card pressed on the roller surface and simultaneously providing anti-pulling friction force when the reagent card and the guide roller slide relatively.
9. The reagent card insertion guide anti-pullout mechanism of claim 8, wherein:
the pressing block is of a rigid block structure with a fixed position, and the guide roller is an elastic extrusion roller.
10. The reagent card insertion guide anti-pullout mechanism according to claim 8 or 9, characterized in that:
the unidirectional rotation locking mechanism includes a lock reset mechanism for resetting the unidirectional rotation locking mechanism to the steering lock state after the unlocking mechanism releases the lock release control of the unidirectional rotation locking mechanism.
11. The reagent card insertion guide anti-pullout mechanism of claim 10, wherein:
the unidirectional rotation locking mechanism is a ratchet mechanism, a ratchet wheel of the unidirectional rotation locking mechanism is fixed on the end part of the guide roller, and a pawl of the unidirectional rotation locking mechanism is fixed on the roller mounting seat; the unlocking mechanism is used for decoupling the pawl from the ratchet wheel.
12. The reagent card insertion guide anti-pullout mechanism according to claim 11, characterized in that:
the pawl is a reed with one end fixed on the roller mounting seat; the unlocking mechanism is an electromagnet and is used for magnetically attracting the free end part of the reed when the unlocking mechanism is electrified so as to enable the free end part to be decoupled from the ratchet wheel;
the guide roller comprises a support mandrel which is rotatably arranged on the roller mounting seat, and an elastic roller which is fixedly sleeved outside the support mandrel; the ratchet wheel is fixed on the end part of the support mandrel;
the lock reset mechanism comprises the reed.
13. The reagent card insertion guide anti-pullout mechanism of claim 10, wherein:
the unidirectional rotation locking mechanism is a unidirectional clutch mechanism; the one-way clutch mechanism comprises a driven part fixedly connected with the roller mounting seat, a driving part fixedly connected with the guide roller and an elastic pressing mechanism; the elastic restoring force of the elastic pressing mechanism is used for forcing the driven part to be in one-way transmission engagement with the driving part; the unlocking mechanism is a clutch operating mechanism and is used for forcing the driven part to overcome the elastic restoring force and disengage from the driving part.
14. The reagent card insertion guide anti-pullout mechanism according to claim 13, characterized in that:
the guide roller comprises a support mandrel fixed on the roller mounting seat and an elastic roller rotatably sleeved outside the support mandrel; the driving part is a first sawtooth groove group which is concavely formed on the end surface of the elastic roller; the first zigzag groove group comprises a plurality of zigzag grooves which are continuously arranged in a circle around the circumference of the support mandrel; in the first zigzag slot group, each zigzag slot comprises a first oblique leading-in and leading-out surface part positioned on the upstream side, a first axial locking surface part positioned on the downstream side and a first transition surface part used for connecting the first oblique leading-in and leading-out surface part and the first axial locking surface part in the opposite direction of the plug-in card;
the unidirectional rotation locking mechanism comprises a stop chuck fixed on the external connection end part of the support mandrel and a sliding sleeve which can rotate and is sleeved outside the support mandrel in an axially sliding manner; the driven part is a second zigzag groove group which is concavely formed on the end surface of the sliding sleeve, and the second zigzag groove group is meshed with the first zigzag groove group; the elastic pressing mechanism is a torsion spring sleeved outside the support core shaft; the sliding sleeve is positioned between the first zigzag groove group and the stop chuck; the spring ring of the torsion spring is pressed between the sliding sleeve and the stopping chuck, and the compressible stroke is greater than the meshing depth of the two groups of sawtooth-shaped grooves; one torsion arm of the torsion spring is coupled to the stop chuck, and the other torsion arm of the torsion spring is coupled to the sliding sleeve;
the unlocking mechanism comprises a driving mechanism and a driving mechanism, wherein the driving mechanism is used for driving the sliding sleeve to overcome the elastic thrust of the spring coil so as to enable the second zigzag groove group to be decoupled from the first zigzag groove group;
the locking reset mechanism comprises the torsion spring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010890189.1A CN112161926B (en) | 2020-08-28 | 2020-08-28 | Fluorescence immunoassay appearance and reagent card cartridge guide anti-pulling mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010890189.1A CN112161926B (en) | 2020-08-28 | 2020-08-28 | Fluorescence immunoassay appearance and reagent card cartridge guide anti-pulling mechanism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112161926A true CN112161926A (en) | 2021-01-01 |
| CN112161926B CN112161926B (en) | 2023-06-23 |
Family
ID=73859569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010890189.1A Active CN112161926B (en) | 2020-08-28 | 2020-08-28 | Fluorescence immunoassay appearance and reagent card cartridge guide anti-pulling mechanism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112161926B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113406029A (en) * | 2021-03-25 | 2021-09-17 | 江苏硕世生物科技股份有限公司 | Detection result reading device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07205504A (en) * | 1994-01-19 | 1995-08-08 | Citizen Watch Co Ltd | Validation paper feed mechanism for printer |
| CN205910201U (en) * | 2016-05-04 | 2017-01-25 | 广州一步医疗科技有限公司 | Sample analytical equipment and full -automatic immunofluorescence analyzer |
| CN109270286A (en) * | 2018-11-26 | 2019-01-25 | 海卫特(广州)医疗科技有限公司 | Card insert type analyzer component, card insert type analyzer and its clutch structure |
| CN209231352U (en) * | 2018-11-26 | 2019-08-09 | 海卫特(广州)医疗科技有限公司 | Reagent analyzer component, reagent analyzer and its fixed structure |
-
2020
- 2020-08-28 CN CN202010890189.1A patent/CN112161926B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07205504A (en) * | 1994-01-19 | 1995-08-08 | Citizen Watch Co Ltd | Validation paper feed mechanism for printer |
| CN205910201U (en) * | 2016-05-04 | 2017-01-25 | 广州一步医疗科技有限公司 | Sample analytical equipment and full -automatic immunofluorescence analyzer |
| CN109270286A (en) * | 2018-11-26 | 2019-01-25 | 海卫特(广州)医疗科技有限公司 | Card insert type analyzer component, card insert type analyzer and its clutch structure |
| CN209231352U (en) * | 2018-11-26 | 2019-08-09 | 海卫特(广州)医疗科技有限公司 | Reagent analyzer component, reagent analyzer and its fixed structure |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113406029A (en) * | 2021-03-25 | 2021-09-17 | 江苏硕世生物科技股份有限公司 | Detection result reading device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112161926B (en) | 2023-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112161926A (en) | Fluorescence immunoassay appearance and reagent card cartridge guide prevent pulling out mechanism | |
| CN114152766B (en) | Sample analyzer and manual sample feeding assembly thereof | |
| CN110554207A (en) | Optical detection device | |
| CN206975056U (en) | A kind of stop detent mechanism of sample conveying device | |
| CN213381619U (en) | Sample analyzer, clamping jaw subassembly | |
| CN211603228U (en) | Optical detection device | |
| CN213749925U (en) | Multi-channel fluorescence immunoassay analyzer | |
| CN211043417U (en) | Analyzer and independent automatic emergency treatment sample injection mechanism thereof | |
| CN111558405A (en) | Driving and liquid adding device for micro-fluidic chip | |
| CN112213506B (en) | Fluorescent immunoassay appearance | |
| CN213986151U (en) | Fluorescence immunoassay appearance and reagent card cartridge groove seat thereof | |
| CN211978493U (en) | Sample analyzer, automatic mixing device of blood sample | |
| CN211374773U (en) | Sample adding and reaction cup adding mechanism for immunity analyzer | |
| CN211505576U (en) | Full-automatic dry immunoassay equipment | |
| CN210294283U (en) | Sample loading mechanism suitable for chemiluminescence immunity analyzer | |
| CN204789599U (en) | Sampling of integration ration adds reagent device piston system of pushing down | |
| CN217060261U (en) | Multi-point-position ejection device and sample tube storage system | |
| CN210108777U (en) | Sampling device for an analyser for analysing a liquid sample | |
| CN104678119A (en) | User-friendly piston pressing system for integrated quantitative sampling reagent adding device | |
| CN218350305U (en) | Sorting, positioning and collecting assembly of high-speed full-automatic biochemical analyzer | |
| CN218524562U (en) | Detection device | |
| CN212417985U (en) | Driving and liquid adding device for micro-fluidic chip | |
| CN217543123U (en) | POCT sample analyzer | |
| CN213381620U (en) | Sample analyzer, clamping jaw device and stacking teeth | |
| CN221007608U (en) | Chemiluminescence immunity analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |