CN112129958A - Microfluidic device, microfluidic reagent disk and using method - Google Patents

Microfluidic device, microfluidic reagent disk and using method Download PDF

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Publication number
CN112129958A
CN112129958A CN202011010152.1A CN202011010152A CN112129958A CN 112129958 A CN112129958 A CN 112129958A CN 202011010152 A CN202011010152 A CN 202011010152A CN 112129958 A CN112129958 A CN 112129958A
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CN
China
Prior art keywords
plug
hole
piston structure
channel
diluent
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Pending
Application number
CN202011010152.1A
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Chinese (zh)
Inventor
廖彦剑
邓苑佐
曾文明
王子孟
李川
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Smic Weikang Medical Technology Chongqing Co ltd
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Smic Weikang Medical Technology Chongqing Co ltd
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Priority to CN202011010152.1A priority Critical patent/CN112129958A/en
Publication of CN112129958A publication Critical patent/CN112129958A/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1032—Dilution or aliquotting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention provides a microfluidic device and a microfluidic reagent disk, wherein the microfluidic device comprises: the diluent sealing shell is internally fixed with a cavity; a plug hole is formed in the diluent sealing shell and the cavity at the same position, and a plug column is arranged in the plug hole in a matched mode, wherein the length of the plug column is larger than the depth of the plug hole; a piston structure is arranged in the cavity, and a spring is sleeved on the piston structure; the cavity is provided with a through hole, the piston structure is fixedly provided with a guide pillar in the moving direction, the guide pillar penetrates through the through hole, and a sealing gasket is arranged at one end far away from the piston structure; the diluent sealing shell is provided with a micro-channel, and the position of the sealing pad corresponds to the position of a channel opening of the micro-channel.

Description

Microfluidic device, microfluidic reagent disk and using method
Technical Field
The invention relates to the technical field of reagent diagnosis, in particular to a microfluidic device, a microfluidic reagent disk and a using method.
Background
POCT-type biochemical analyzers require that a sample be diluted before reacting with a reagent. For convenience of use, the sample diluent is placed in the reagent tray in advance, and the sample is added into the reagent tray for dilution during detection. However, during storage and transportation, the sample diluent is easily evaporated to form water vapor, and the water vapor enters the colorimetric holes along the flow channels on the reagent tray, so that the reagents placed in the colorimetric holes fail to absorb moisture. Therefore, how to store the sample diluent becomes a problem.
The existing method is to hold the sample diluent in a cavity, then seal the cavity with a film, and seal the diluent. When the reagent tray is used, the bottom of the diluent sealing cavity and the top of the diluent sealing cavity are firstly punctured, so that an opening in the top is communicated with the atmosphere, diluent enters the reagent tray under the action of centrifugal force, and the method needs a process of opening twice. The puncturing actions in each operation are not consistent, so that the film opening is not ideal, the overflowing interface is not fixed, the diluent is not completely released, and the sample dilution ratio is deviated in the test process.
Disclosure of Invention
The invention aims to provide a microfluidic device, a microfluidic reagent disk and a using method, which realize effective preservation of sample diluent and facilitate the use of the sample diluent.
The technical scheme provided by the invention is as follows:
the present invention provides a microfluidic device comprising: the diluent sealing shell is internally fixed with a cavity; a plug hole is formed in the diluent sealing shell and the cavity at the same position, and a plug column is arranged in the plug hole in a matched mode, wherein the length of the plug column is larger than the depth of the plug hole; a piston structure is arranged in the cavity, and a spring is sleeved on the piston structure; the cavity is provided with a through hole, the piston structure is fixedly provided with a guide pillar in the moving direction, the guide pillar penetrates through the through hole, and a sealing gasket is arranged at one end far away from the piston structure; the diluent sealing shell is provided with a micro-channel, and the position of the sealing pad corresponds to the position of a channel opening of the micro-channel.
In one embodiment, the through hole is located on the side of the cavity, the channel opening of the microchannel is located on the side of the diluent-tight casing, and the through hole and the channel opening of the microchannel are located in the same direction.
In one embodiment, when the plug is inserted into the plug hole, the extension part of the plug inserted into the plug hole presses the piston structure towards the through hole, so that the spring on the piston structure is compressed, and the sealing gasket of the guide pillar seals the micro flow channel; when the plug is pulled out of the plug hole, the spring pushes the piston structure in the direction away from the through hole, so that the sealing gasket of the guide post is separated from the micro flow channel.
In one embodiment, the plug head of the plug has an incline slope.
The application also provides a microfluidic reagent disk, wherein a microfluidic device is fixedly arranged on the microfluidic reagent disk; the microfluidic device comprises: the diluent sealing shell is internally fixed with a cavity; a plug hole is formed in the diluent sealing shell and the cavity at the same position, and a plug column is arranged in the plug hole in a matched mode, wherein the length of the plug column is larger than the depth of the plug hole; a piston structure is arranged in the cavity, and a spring is sleeved on the piston structure; the cavity is provided with a through hole, the piston structure is fixedly provided with a guide pillar in the moving direction, the guide pillar penetrates through the through hole, and a sealing gasket is arranged at one end far away from the piston structure; the diluent sealing shell is provided with a micro-channel, and the position of the sealing pad corresponds to the position of a channel opening of the micro-channel; the diluent sealing shell is connected with a vent hole, and the vent hole is communicated with the diluent sealing shell through a pipeline; the microfluidic reagent disk also comprises a sample inlet; the micro-fluidic reagent disk is pasted with an easily torn sealing film, and the easily torn sealing film simultaneously seals the sample inlet and the air vent and is pasted with the plug.
In one embodiment, the through hole is located on the side of the cavity, the channel opening of the microchannel is located on the side of the diluent-tight casing, and the through hole and the channel opening of the microchannel are located in the same direction.
In one embodiment, when the plug is inserted into the plug hole, the extension part of the plug inserted into the plug hole presses the piston structure towards the through hole, so that the spring on the piston structure is compressed, and the sealing gasket of the guide pillar seals the micro flow channel; when the plug is pulled out of the plug hole, the spring pushes the piston structure in the direction away from the through hole, so that the sealing gasket of the guide post is separated from the micro flow channel.
In one embodiment, a waterproof breathable film is further sealed on the vent hole.
In one embodiment, the plug head of the plug has an incline slope.
The invention also provides a use method of the microfluidic reagent disk, which is used for the microfluidic reagent disk, when the microfluidic reagent disk is used, the easily-torn sealing film is torn off, so that the vent hole and the sample inlet are exposed, the plug is fallen off, and then sample introduction is started from the sample inlet.
The microfluidic device and the microfluidic reagent disk provided by the invention can well store sample diluent. According to the invention, the sample inlet, the vent hole and the plunger piston are simultaneously sealed by the easy-to-tear sealing film, when the reagent disk is used, the plunger piston can be taken out only by uncovering the easy-to-tear sealing film, and the vent hole covered by the waterproof breathable film is opened, so that the interior of the diluent liquid-tight shell is communicated with the atmosphere, and the diluent is released to the designated area of the reagent disk without hindrance. And simultaneously, opening a sample inlet to start sample injection. The use steps in use by the user are simplified.
Drawings
The above features, technical features, advantages and implementations of a microfluidic device, a microfluidic reagent disk and a method of using the same will be further described in the following preferred embodiments in a clearly understandable manner with reference to the accompanying drawings.
FIG. 1 is a schematic diagram of a microfluidic device according to the present invention;
FIG. 2 is a schematic diagram of the structure of a microfluidic reagent disk according to the present invention;
FIG. 3 is a cross-sectional view of a microfluidic reagent disk according to the present invention;
1-shell, 2-cavity, 3-plug hole, 4-plug column, 5-piston structure, 6-spring, 7-through hole, 8-guide column, 9-sealing pad, 10-micro channel, 11-vent hole, 13-reagent disk packaging film, 14-easy-tear sealing film, 15-waterproof breathable film, 16-diluent placing area and 17-microfluidic device.
Detailed Description
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following description will be made with reference to the accompanying drawings. It is obvious that the drawings in the following description are only some examples of the invention, and that for a person skilled in the art, other drawings and embodiments can be derived from them without inventive effort.
For the sake of simplicity, the drawings only schematically show the parts relevant to the present invention, and they do not represent the actual structure as a product. In addition, in order to make the drawings concise and understandable, components having the same structure or function in some of the drawings are only schematically illustrated or only labeled. In this document, "one" means not only "only one" but also a case of "more than one".
As shown in fig. 1, the present invention provides an embodiment of a microfluidic device 17, the microfluidic device 17 comprising:
the diluent sealing shell is characterized in that a cavity 2 is fixed inside the diluent sealing shell 1; as shown in fig. 1, the chamber 2 may be fixedly disposed at the upper end of the diluent tight casing 1.
The diluent sealed shell 1 and the cavity 2 are provided with a plug hole 3 at the same position, that is, as shown in fig. 1, the diluent sealed shell 1 and the cavity 2 are provided with a plug hole 3 at the same upper position, and the plug hole 3 is provided with a plug 4 arranged in a matching manner to keep the plug hole 3 sealed. Preferably, the cavity 2 can be fixedly arranged on the inner surface of the diluent sealing shell 1, a plug hole 3 is arranged at the same position, the plug hole 3 is a through hole 7, and the plug hole 3 is also provided with a plug 4 for sealing.
A through hole 7 is formed in the side portion of the cavity 2, a piston structure 5 is arranged in the cavity 2, and a spring 6 is sleeved on the piston structure 5; a guide post 8 is fixedly arranged on the piston structure 5 in the moving direction, the guide post 8 penetrates through the through hole 7, and a sealing gasket 9 is arranged at one end far away from the piston structure 5; the side part of the diluent sealed shell 1 is provided with a micro-channel 10, and the position of the sealing gasket 9 corresponds to the channel opening of the micro-channel 10.
When the plug 4 is inserted into the plug hole 3, the plug 4 is inserted into the extending part of the plug hole 3 to press the piston structure 5 towards the through hole 7, so that the spring 6 on the piston structure 5 is compressed, and the sealing gasket 9 of the guide post 8 seals the micro flow channel 10; at this time, the diluent contained in the diluent close casing 1 is sealed.
When the plug 4 is pulled out of the plug hole 3, the spring 6 pushes the piston structure 5 in a direction away from the through hole 7, so that the sealing gasket 9 of the guide post 8 is separated from the micro flow channel 10. At this time, the diluent flows out through the microchannel 10.
In a preferred embodiment, the plug head of the plug 4 has an inclined slope, which is convenient when the plug 4 is plugged inwards.
In a preferred embodiment, the through hole 7 is located at the side of the cavity 2, the channel opening of the microchannel 10 is located at the side of the diluent-tight casing 1, and the through hole 7 and the channel opening of the microchannel 10 are located at the same direction.
Through the microfluidic device provided by the invention, the operation of a user is very simple and convenient, and the opening is not required to be punctured to make diluent flow out like the prior art.
As shown in fig. 2, the present invention provides one embodiment of a microfluidic reagent disk comprising: the reagent disk is fixedly provided with a microfluidic device 17;
the microfluidic device 17 comprises:
the diluent sealing device comprises a diluent sealing shell 1, wherein a cavity 2 is fixed inside the diluent sealing shell 1;
a plug hole 3 is formed in the diluent sealing shell 1 and the cavity 2 at the same position, and a plug column 4 is arranged on the plug hole 3 in a matched mode, wherein the length of the plug column 4 is larger than the depth of the plug hole 3;
a through hole 7 is formed in the side portion of the cavity 2, a piston structure 5 is arranged in the cavity 2, and a spring 6 is sleeved on the piston structure 5;
a guide post 8 is fixedly arranged on the piston structure 5 in the moving direction, the guide post 8 penetrates through the through hole 7, and a sealing gasket 9 is arranged at one end far away from the piston structure 5; a micro-channel 10 is arranged on the side part of the diluent sealed shell 1, and the position of the sealing gasket 9 corresponds to the channel opening of the micro-channel 10;
when the plug 4 is inserted into the plug hole 3, the plug 4 is inserted into the extending part of the plug hole 3 to extrude the piston structure 5 towards the through hole 7, so that the spring 6 on the piston structure 5 is compressed, and the sealing gasket 9 of the guide post 8 arranged on the piston structure 5 seals the micro channel 10;
when the plug 4 is pulled out of the plug hole 3, the spring 6 is restored from a compressed state, and the spring 6 pushes the piston structure 5 in a direction away from the through hole 7, so that the sealing gasket 9 of the guide post 8 is separated from the micro flow channel 10.
The diluent sealed shell 1 is connected with a vent hole 11, and the vent hole 11 is communicated with the diluent sealed shell 1 through a pipeline; the micro-fluidic reagent disk further comprises a sample inlet and a sealing film 14 easy to tear, wherein the sealing film easy to tear seals the sample inlet at the same time, and the vent hole 11 is pasted with the plug 4.
The invention also provides an embodiment of a using method of the microfluidic reagent disk, as shown in fig. 3, when the microfluidic reagent disk is used, the easily-torn sealing film is directly uncovered, the plunger connected with the easily-torn sealing film 14 is taken out, so that the sealing gasket 9 of the guide post 8 is separated from the micro flow channel 10, meanwhile, the vent hole 11 covered by the waterproof breathable film 15 is also opened, so that the interior of the diluent sealing shell 1 is communicated with the atmosphere, and the sample inlet is also opened to start sample injection. Therefore, when the sealing film is used, a user only needs to directly tear off the easily-torn sealing film, and the using steps of the user are simplified.
It should be noted that the above embodiments can be freely combined as necessary. The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (10)

1. A microfluidic device, comprising:
the diluent sealing shell is internally fixed with a cavity;
a plug hole is formed in the diluent sealing shell and the cavity at the same position, and a plug column is arranged in the plug hole in a matched mode, wherein the length of the plug column is larger than the depth of the plug hole;
a piston structure is arranged in the cavity, and a spring is sleeved on the piston structure; the cavity is provided with a through hole, the piston structure is fixedly provided with a guide pillar in the moving direction, the guide pillar penetrates through the through hole, and a sealing gasket is arranged at one end, far away from the piston structure, of the guide pillar; the diluent sealing shell is provided with a micro-channel, and the position of the sealing pad corresponds to the position of a channel opening of the micro-channel.
2. The microfluidic device according to claim 1, wherein the through hole is located at a side of the chamber, the channel opening of the microchannel is located at a side of the diluent-tight housing, and the through hole and the channel opening of the microchannel are located at the same direction.
3. A microfluidic device according to claim 1, wherein:
when the plug is inserted into the plug hole, the plug is inserted into the extending part of the plug hole to extrude the piston structure towards the direction of the through hole, so that the spring on the piston structure is compressed, and the sealing gasket of the guide post seals the micro-channel;
when the plug is pulled out of the plug hole, the spring pushes the piston structure in the direction away from the through hole, so that the sealing gasket of the guide post is separated from the micro flow channel.
4. A microfluidic device according to claim 1, wherein the plug head of the plug has an inclined slope.
5. The microfluidic reagent disk is characterized in that a microfluidic device is fixedly arranged on the microfluidic reagent disk;
the microfluidic device comprises:
the diluent sealing shell is internally fixed with a cavity;
a plug hole is formed in the diluent sealing shell and the cavity at the same position, and a plug column is arranged in the plug hole in a matched mode, wherein the length of the plug column is larger than the depth of the plug hole;
a piston structure is arranged in the cavity, and a spring is sleeved on the piston structure; the cavity is provided with a through hole, the piston structure is fixedly provided with a guide pillar in the moving direction, the guide pillar penetrates through the through hole, and a sealing gasket is arranged at one end far away from the piston structure; the diluent sealing shell is provided with a micro-channel, and the position of the sealing pad corresponds to the position of a channel opening of the micro-channel;
the diluent sealing shell is connected with a vent hole, and the vent hole is communicated with the diluent sealing shell through a pipeline; the microfluidic reagent disk also comprises a sample inlet;
the micro-fluidic reagent disk is pasted with an easily torn sealing film, and the easily torn sealing film simultaneously seals the sample inlet and the air vent and is pasted with the plug.
6. A microfluidic reagent disk according to claim 5, wherein: the through hole is positioned on the side part of the cavity, the channel port of the micro-channel is positioned on the side part of the diluent sealing shell, and the through hole and the channel port of the micro-channel are positioned in the same direction.
7. A microfluidic reagent disk according to claim 5, wherein:
when the plug is inserted into the plug hole, the plug is inserted into the extending part of the plug hole to extrude the piston structure towards the direction of the through hole, so that the spring on the piston structure is compressed, and the sealing gasket of the guide post seals the micro-channel;
when the plug is pulled out of the plug hole, the spring pushes the piston structure in the direction away from the through hole, so that the sealing gasket of the guide post is separated from the micro flow channel.
8. A microfluidic reagent disk according to claim 5, wherein the vent hole is further sealed with a waterproof and breathable membrane.
9. A microfluidic reagent disk according to claim 5, wherein:
the plug head of the plug column has an incline grade.
10. The use method of the microfluidic reagent disk is characterized in that the use method is used for the microfluidic reagent disk of any one of claims 5 to 9, and when the microfluidic reagent disk is used, the easily-torn sealing film is torn off, so that the vent hole and the sample inlet are exposed, the plug is separated, and then sample injection is started from the sample inlet.
CN202011010152.1A 2020-09-23 2020-09-23 Microfluidic device, microfluidic reagent disk and using method Pending CN112129958A (en)

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CN202011010152.1A CN112129958A (en) 2020-09-23 2020-09-23 Microfluidic device, microfluidic reagent disk and using method

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CN202011010152.1A CN112129958A (en) 2020-09-23 2020-09-23 Microfluidic device, microfluidic reagent disk and using method

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102200536A (en) * 2010-03-25 2011-09-28 艾博生物医药(杭州)有限公司 Device for detecting analyzed objects in test liquid samples
CN105214745A (en) * 2015-10-26 2016-01-06 深圳华迈兴微医疗科技有限公司 A kind of micro-fluidic chip
CN108479867A (en) * 2018-03-01 2018-09-04 深圳韦尔达科技合伙企业（有限合伙） Centrifugal type microfludic chip reagent encapsulating structure and centrifugal type microfludic chip component
WO2018192809A1 (en) * 2017-04-18 2018-10-25 Robert Bosch Gmbh Apparatus and method for a microfluidic system for analyzing a sample
CN109630401A (en) * 2018-11-16 2019-04-16 南京肯辛顿诊断科技有限公司 A kind of syringe pump for micro fluidic device
CN111443195A (en) * 2020-04-02 2020-07-24 深圳市易瑞生物技术股份有限公司 Immunoassay reagent card

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102200536A (en) * 2010-03-25 2011-09-28 艾博生物医药(杭州)有限公司 Device for detecting analyzed objects in test liquid samples
CN105214745A (en) * 2015-10-26 2016-01-06 深圳华迈兴微医疗科技有限公司 A kind of micro-fluidic chip
WO2018192809A1 (en) * 2017-04-18 2018-10-25 Robert Bosch Gmbh Apparatus and method for a microfluidic system for analyzing a sample
CN108479867A (en) * 2018-03-01 2018-09-04 深圳韦尔达科技合伙企业（有限合伙） Centrifugal type microfludic chip reagent encapsulating structure and centrifugal type microfludic chip component
CN109630401A (en) * 2018-11-16 2019-04-16 南京肯辛顿诊断科技有限公司 A kind of syringe pump for micro fluidic device
CN111443195A (en) * 2020-04-02 2020-07-24 深圳市易瑞生物技术股份有限公司 Immunoassay reagent card

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