CN112089777A - Erection-promoting time-delay agent for male and preparation method thereof - Google Patents
Erection-promoting time-delay agent for male and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention relates to the technical field of biological medical treatment, in particular to a male erection aid time-delay agent and a preparation method thereof, wherein the male erection aid time-delay agent comprises the following raw materials: herba Epimedii, fructus Cnidii, Ginseng radix, Cistanchis herba, flos Caryophylli, stigma croci Sativi, cortex Cinnamomi, fructus Zanthoxyli, semen Cuscutae and chlorhexidine gluconate; the method comprises cleaning and sterilizing the required operation equipment, mixing herba Epimedii, fructus Cnidii, Cistanchis herba, flos Caryophylli, stigma croci Sativi, cortex Cinnamomi, fructus Zanthoxyli and semen Cuscutae, grinding into powder, and making into powder mixture; adding the powder mixture into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid; centrifuging and filtering the extract to obtain a concentrated solution; adding chlorhexidine gluconate into the concentrated solution to obtain male erection aid time-delay agent; the invention provides a male erection aid time-delay agent with no side effect and good curative effect.
Description
Technical Field
The invention relates to the technical field of biological medical treatment, in particular to a male erection aid time-delay agent and a preparation method thereof.
Background
Premature ejaculation is the most common dysfunction of ejaculation, which is mainly manifested by the inability to perform normal sexual life, i.e. the ejaculation at the beginning of sexual intercourse, even the ejaculation before sexual intercourse, with a disease rate of over 1/3 of adult men. The etiology of premature ejaculation includes psychological and organic factors. The psychological factors causing premature ejaculation are many, for example, many people are afraid of sexual failure and emotional anxiety due to various reasons to cause premature ejaculation; the purpose of quickly reaching the climax is always achieved by the common masturbation in young age; lack of sexual knowledge, which is only aimed at satisfying men; the couple is not in intimate cooperation; emotional upset, aversion to spouses, conscious or unconscious abuse awareness; fear of sexual behavior damaging health and aggravating certain inherent diseases of the body; those with too little frequency or prolonged depression of sexual intercourse; and aversion to intercourse, worry about palpitations, urge to end sexual intercourse, etc. in the female. All kinds of them can cause premature ejaculation and even produce a chain reaction, which affects the erection ability. Organic factors causing premature ejaculation are under investigation, and spinal cord diseases such as multiple sclerosis or spinal cord tumor, epileptic seizure or cerebral cortical organic diseases such as cerebrovascular accident can cause the loss of control of ejaculation. It has also been reported that diabetes, cardiovascular diseases, pelvic fracture, genitourinary system diseases such as urethritis, prostatitis, seminal vesiculitis, and prostatic hyperplasia are all related to premature ejaculation.
The treatment for premature ejaculation mainly comprises: 1. psychotherapy, namely eliminating abnormal psychology of anxiety, uneasiness, guilt and the like of a patient and establishing confidence for curing diseases; 2. behavioral method guidance; 3. pharmacotherapy, currently drug therapy is mainly 5-hydroxytryptamine reuptake inhibitors such as sertraline and paroxetine; tricyclic antidepressants such as clomipramine and fluoxetine, and the like. However, the medicines all have certain side effects and are required to be taken under the guidance of doctors; 4. the dorsal penile nerve amputation is still in trial abroad. Although the effect is recognized to some extent, its safety and effectiveness are still under investigation. It is only suitable for married primary premature ejaculation patients, and the patients must have received long-term medicine, psychological and behavioral therapy and little curative effect. For patients who can improve ejaculation time by drugs or patients with secondary premature ejaculation, surgery is not considered.
In conclusion, the prior art also lacks a male erection-promoting time-delay agent with no side effect and good curative effect.
Disclosure of Invention
Aiming at the problems, the invention discloses a male erection aid time-delay agent with no side effect and good curative effect and a preparation method thereof.
The invention provides a male erection aid time-delay agent, which comprises the following raw materials: herba Epimedii, fructus Cnidii, Ginseng radix, Cistanchis herba, flos Caryophylli, stigma croci Sativi, cortex Cinnamomi, fructus Zanthoxyli, semen Cuscutae and chlorhexidine gluconate.
The common cnidium fruit is mainly used: dry dampness, dispel wind, kill parasites, warm kidney and strengthen yang. Can be used for treating sexual impotence, cold womb, leukorrhagia due to cold-dampness, and lumbago due to damp arthralgia; it can be used for treating vulval eczema, pudendal pruritus, and trichomonal vaginitis. The cnidium fruit has the function of erection aid in the erection aid time delay agent.
Cistanche deserticola is used for tonifying kidney yang; replenishing essence and blood; moistening intestinal tract. Deficiency of both the major and kidney yang; impotence due to deficiency of essence and blood; spermatorrhea; white turbidity; frequent micturition and dribbling; lumbago and weak feet; tinnitus and blurred vision; menstrual period of menstruation; infertility due to cold uterus; constipation due to intestinal dryness. The cnidium fruit in the erection aid time-delay agent has the function of preventing premature ejaculation.
Preferably, the raw materials comprise the following components in parts by weight: 1-5 parts of longspur epimedium, 1-10 parts of common cnidium fruit, 1-5 parts of ginseng, 1-5 parts of desertliving cistanche, 1-10 parts of clove, 1-15 parts of saffron, 1-5 parts of cinnamon, 1-5 parts of pericarpium zanthoxyli, 1-5 parts of dodder and 0.1-0.5 part of chlorhexidine gluconate.
Preferably, the epimedium herb grade is a medical grade, the common cnidium fruit grade is a medical grade, the ginseng grade is a medical grade, the desertliving cistanche grade is a medical grade, the clove grade is a medical grade, the saffron crocus grade is a medical grade, the cinnamon grade is a medical grade, the pericarpium zanthoxyli grade is a medical grade, the dodder grade is a medical grade, and the chlorhexidine gluconate grade is a cosmetic grade.
The second aspect of the invention provides a preparation method of a male erection aid time-delay agent, which comprises the following specific steps:
s1, operation equipment required by washing and sterilization;
s2, mixing herba Epimedii, fructus Cnidii, herba cistanches, flos Caryophylli, stigma croci, cortex Cinnamomi, pericarpium Zanthoxyli, and semen Cuscutae, grinding into powder, and making into powder mixture;
s3, adding the powder mixture obtained in the step S2 into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid;
s4, centrifuging and filtering the extract liquor obtained in the step S3 to obtain a concentrated solution;
s5, adding chlorhexidine gluconate into the concentrated solution obtained in S4 to obtain male erection aid time-delay agent.
Preferably, the ultrasonic physical extraction conditions of step S3 are: the ultrasonic power is 800-.
Preferably: step S2 also includes passing the powder mixture through a 20-50 mesh screen.
The male erection aid time-delay agent acts on the coronary sulcus part and plays a role in repairing local mucosa, thereby reducing the sensitivity of external genitalia, improving the stimulation intensity of stimulating ejaculation and prolonging the ejaculation time. After contacting and absorbing the male erection aid time-delay agent, a layer of cuticle is gradually formed on the surface of the glans penis to play a role in protecting the glans penis.
Compared with the prior art, the invention has the following advantages or beneficial effects: the male erection aid time-delay agent provided by the invention can effectively delay premature ejaculation; in addition, the male erection aid time-delay agent is made of natural materials, is easy to obtain and has no side effect.
Detailed Description
Those skilled in the art will appreciate that variations may be implemented by those skilled in the art in combination with the prior art and the above-described embodiments, and will not be described herein in detail. Such variations do not affect the essence of the present invention and are not described herein.
Example 1
A male erection aid time-delay agent comprises the following raw materials in parts by weight:
5 parts of longspur epimedium, 10 parts of common cnidium fruit, 5 parts of ginseng, 5 parts of desertliving cistanche, 10 parts of clove, 15 parts of saffron, 5 parts of cinnamon, 5 parts of pericarpium zanthoxyli, 5 parts of dodder and 0.5 part of chlorhexidine gluconate.
Wherein the epimedium herb grade is a medical grade, the common cnidium fruit grade is a medical grade, the ginseng grade is a medical grade, the desertliving cistanche grade is a medical grade, the clove grade is a medical grade, the saffron crocus grade is a medical grade, the cinnamon grade is a medical grade, the pericarpium zanthoxyli grade is a medical grade, the dodder grade is a medical grade, and the chlorhexidine gluconate grade is a cosmetic grade.
The preparation method of the male erection-promoting time-delay agent is characterized in that: the method comprises the following specific steps:
s1, operation equipment required by washing and sterilization;
s2, mixing herba Epimedii, fructus Cnidii, herba cistanches, flos Caryophylli, stigma croci, cortex Cinnamomi, pericarpium Zanthoxyli, and semen Cuscutae, grinding into powder, and making into powder mixture; sieving the powder mixture through a 50-mesh sieve;
s3, adding the powder mixture obtained in the step S2 into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid; the extraction conditions of the ultrasonic physical method are as follows: the ultrasonic power is 1800W, the emission frequency is 60KHz, the pulse cycle frequency is 10 times/second, and the sound velocity is 3000 m/second;
s4, centrifuging and filtering the extract liquor obtained in the step S3 to obtain a concentrated solution;
s5, adding chlorhexidine gluconate into the concentrated solution obtained in S4 to obtain male erection aid time-delay agent.
Example 2
A male erection aid time-delay agent comprises the following raw materials in parts by weight:
1 part of longspur epimedium, 1 part of common cnidium fruit, 1 part of ginseng, 1 part of desertliving cistanche, 1 part of clove, 1 part of saffron, 1 part of cinnamon, 1 part of pericarpium zanthoxyli, 1 part of dodder and 0.1 part of chlorhexidine gluconate.
Wherein the epimedium herb grade is a medical grade, the common cnidium fruit grade is a medical grade, the ginseng grade is a medical grade, the desertliving cistanche grade is a medical grade, the clove grade is a medical grade, the saffron crocus grade is a medical grade, the cinnamon grade is a medical grade, the pericarpium zanthoxyli grade is a medical grade, the dodder grade is a medical grade, and the chlorhexidine gluconate grade is a cosmetic grade.
The preparation method of the male erection-promoting time-delay agent is characterized in that: the method comprises the following specific steps:
s1, operation equipment required by washing and sterilization;
s2, mixing herba Epimedii, fructus Cnidii, herba cistanches, flos Caryophylli, stigma croci, cortex Cinnamomi, pericarpium Zanthoxyli, and semen Cuscutae, grinding into powder, and making into powder mixture; sieving the powder mixture through a 20-mesh sieve;
s3, adding the powder mixture obtained in the step S2 into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid; the extraction conditions of the ultrasonic physical method are as follows: the ultrasonic power is 800W, the emission frequency is 40KHz, the pulse period frequency is 2 times/second, and the sound velocity is 1000 m/second;
s4, centrifuging and filtering the extract liquor obtained in the step S3 to obtain a concentrated solution;
s5, adding chlorhexidine gluconate into the concentrated solution obtained in S4 to obtain male erection aid time-delay agent.
Example 3
A male erection aid time-delay agent comprises the following raw materials in parts by weight:
2 parts of longspur epimedium, 2 parts of common cnidium fruit, 2 parts of ginseng, 2 parts of desertliving cistanche, 2 parts of clove, 2 parts of saffron, 2 parts of cinnamon, 2 parts of pericarpium zanthoxyli, 2 parts of dodder and 0.2 part of chlorhexidine gluconate.
Wherein the epimedium herb grade is a medical grade, the common cnidium fruit grade is a medical grade, the ginseng grade is a medical grade, the desertliving cistanche grade is a medical grade, the clove grade is a medical grade, the saffron crocus grade is a medical grade, the cinnamon grade is a medical grade, the pericarpium zanthoxyli grade is a medical grade, the dodder grade is a medical grade, and the chlorhexidine gluconate grade is a cosmetic grade.
The preparation method of the male erection-promoting time-delay agent is characterized in that: the method comprises the following specific steps:
s1, operation equipment required by washing and sterilization;
s2, mixing herba Epimedii, fructus Cnidii, herba cistanches, flos Caryophylli, stigma croci, cortex Cinnamomi, pericarpium Zanthoxyli, and semen Cuscutae, grinding into powder, and making into powder mixture; sieving the powder mixture through a 30-mesh sieve;
s3, adding the powder mixture obtained in the step S2 into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid; the extraction conditions of the ultrasonic physical method are as follows: the ultrasonic power is 1000W, the emission frequency is 50KHz, the pulse period frequency is 8 times/second, and the sound velocity is 2000 m/second;
s4, centrifuging and filtering the extract liquor obtained in the step S3 to obtain a concentrated solution;
s5, adding chlorhexidine gluconate into the concentrated solution obtained in S4 to obtain male erection aid time-delay agent.
The above description is of the preferred embodiment of the invention. It is to be understood that the invention is not limited to the particular embodiments described above, in that devices and structures not described in detail are understood to be implemented in a manner common in the art; those skilled in the art can make many possible variations and modifications to the disclosed embodiments, or modify equivalent embodiments to equivalent variations, without departing from the spirit of the invention, using the methods and techniques disclosed above. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention are still within the scope of the protection of the technical solution of the present invention, unless the contents of the technical solution of the present invention are departed.
Claims (7)
1. The erection-promoting time-delay agent for men is characterized by comprising the following raw materials: herba Epimedii, fructus Cnidii, Ginseng radix, Cistanchis herba, flos Caryophylli, stigma croci Sativi, cortex Cinnamomi, fructus Zanthoxyli, semen Cuscutae and chlorhexidine gluconate.
2. The male erection aid time-delay agent as claimed in claim 1, wherein the weight parts of the raw materials are as follows: 1-5 parts of longspur epimedium, 1-10 parts of common cnidium fruit, 1-5 parts of ginseng, 1-5 parts of desertliving cistanche, 1-10 parts of clove, 1-15 parts of saffron, 1-5 parts of cinnamon, 1-5 parts of pericarpium zanthoxyli, 1-5 parts of dodder and 0.1-0.5 part of chlorhexidine gluconate.
3. The male erection aid time-delay agent as claimed in claim 2, wherein the weight parts of the raw materials are as follows: 2 parts of longspur epimedium, 2 parts of common cnidium fruit, 2 parts of ginseng, 2 parts of desertliving cistanche, 2 parts of clove, 2 parts of saffron, 2 parts of cinnamon, 2 parts of pericarpium zanthoxyli, 2 parts of dodder and 0.2 part of chlorhexidine gluconate.
4. The male erection aid time-delay agent of claim 1, wherein the epimedium herb grade is a pharmaceutical grade, the fructus cnidii grade is a pharmaceutical grade, the ginseng grade is a pharmaceutical grade, the cistanche grade is a pharmaceutical grade, the clove grade is a pharmaceutical grade, the saffron grade is a pharmaceutical grade, the cinnamon grade is a pharmaceutical grade, the pericarpium zanthoxyli grade is a pharmaceutical grade, the semen cuscutae grade is a pharmaceutical grade, and the chlorhexidine gluconate grade is a cosmetic grade.
5. A method of preparing a male erection aid delaying agent as claimed in any one of claims 1 to 4, wherein: the method comprises the following specific steps:
s1, operation equipment required by washing and sterilization;
s2, mixing herba Epimedii, fructus Cnidii, herba cistanches, flos Caryophylli, stigma croci, cortex Cinnamomi, pericarpium Zanthoxyli, and semen Cuscutae, grinding into powder, and making into powder mixture;
s3, adding the powder mixture obtained in the step S2 into an aqueous solution, and extracting by adopting an ultrasonic physical method to obtain an extract liquid;
s4, centrifuging and filtering the extract liquor obtained in the step S3 to obtain a concentrated solution;
s5, adding chlorhexidine gluconate into the concentrated solution obtained in S4 to obtain male erection aid time-delay agent.
6. The method for preparing a male erection aid time-delay agent as claimed in claim 5, wherein the ultrasonic physical extraction conditions of step S3 are as follows: the ultrasonic power is 800-.
7. The method of preparing a male erection aid time-delay agent as claimed in claim 5, wherein: step S2 also includes passing the powder mixture through a 20-50 mesh screen.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797265A (en) * | 2021-10-29 | 2021-12-17 | 上海纳米技术及应用国家工程研究中心有限公司 | Formula for relieving decrease of sexual life quality and preparation process thereof |
| CN115300556A (en) * | 2022-07-11 | 2022-11-08 | 江西神你卫生用品有限公司 | Erection-promoting time-delay agent for male and preparation method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111110764A (en) * | 2020-03-20 | 2020-05-08 | 陈新 | Herbal externally-applied erectile dysfunction care solution and preparation method thereof |
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| CN1107356A (en) * | 1993-09-14 | 1995-08-30 | 崔馨基 | Pharmaceutical composition for prophylaxis and treatment of premature ejaculation |
| CN1907393A (en) * | 2006-08-29 | 2007-02-07 | 戴汉新 | Traditional Chinese medicine composition for treating asthma and sexual disorder |
| CN102250738A (en) * | 2011-06-24 | 2011-11-23 | 李庆合 | Health-care wine and production process thereof |
| CN107158199A (en) * | 2017-06-09 | 2017-09-15 | 安振东 | A kind of Male external spray and preparation method thereof |
| CN108635448A (en) * | 2018-05-10 | 2018-10-12 | 江苏善唯斯生物科技有限公司 | A kind of truffle maca bacteriostasis spray |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113797265A (en) * | 2021-10-29 | 2021-12-17 | 上海纳米技术及应用国家工程研究中心有限公司 | Formula for relieving decrease of sexual life quality and preparation process thereof |
| CN115300556A (en) * | 2022-07-11 | 2022-11-08 | 江西神你卫生用品有限公司 | Erection-promoting time-delay agent for male and preparation method thereof |
| CN115300556B (en) * | 2022-07-11 | 2024-03-22 | 江西神你卫生用品有限公司 | Male erection-assisting time-delay agent and preparation method thereof |
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