CN112057718A - Barrier material for respiratory system - Google Patents
Barrier material for respiratory system Download PDFInfo
- Publication number
- CN112057718A CN112057718A CN202010859117.0A CN202010859117A CN112057718A CN 112057718 A CN112057718 A CN 112057718A CN 202010859117 A CN202010859117 A CN 202010859117A CN 112057718 A CN112057718 A CN 112057718A
- Authority
- CN
- China
- Prior art keywords
- polyvinyl alcohol
- barrier material
- respiratory system
- woven fabric
- antibacterial peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 25
- 230000004888 barrier function Effects 0.000 title claims abstract description 17
- 210000002345 respiratory system Anatomy 0.000 title claims abstract description 15
- 239000004372 Polyvinyl alcohol Substances 0.000 claims abstract description 30
- 229920002451 polyvinyl alcohol Polymers 0.000 claims abstract description 30
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 21
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims abstract description 15
- 238000001179 sorption measurement Methods 0.000 claims description 9
- 238000009736 wetting Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 26
- 244000000010 microbial pathogen Species 0.000 abstract description 13
- 238000001914 filtration Methods 0.000 abstract description 12
- 238000010521 absorption reaction Methods 0.000 abstract description 9
- 239000000835 fiber Substances 0.000 abstract description 7
- 230000014759 maintenance of location Effects 0.000 abstract description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract description 5
- 206010011409 Cross infection Diseases 0.000 abstract description 4
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 4
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract description 4
- 230000003020 moisturizing effect Effects 0.000 abstract description 2
- 239000002245 particle Substances 0.000 description 7
- 208000032376 Lung infection Diseases 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 230000000241 respiratory effect Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 108700042778 Antimicrobial Peptides Proteins 0.000 description 1
- 102000044503 Antimicrobial Peptides Human genes 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000006136 alcoholysis reaction Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 210000004081 cilia Anatomy 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 210000001533 respiratory mucosa Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/04—Tracheal tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/16—Devices to humidify the respiration air
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7509—General characteristics of the apparatus with filters for virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7518—General characteristics of the apparatus with filters bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
Abstract
The invention belongs to the technical field of medical treatment, and particularly relates to a barrier material for a respiratory system. Through the cooperation of non-woven fabrics air flue, absorption moist layer, have biological filtration concurrently and filter pathogenic microorganism with physics, can heat the breathing gas or the air of moisturizing again. The polyvinyl alcohol and the antibacterial peptide are both polar materials, so that the biocompatibility is good; the polyvinyl alcohol contains a large amount of hydroxyl groups, and has good water absorption and moisture retention capacity; the polyvinyl alcohol expands after absorbing water, the fiber density is increased, and the physical filtration performance is improved; the antibacterial peptide kills pathogenic microorganisms in a humidified state, and has excellent biological filtration performance; preventing cross infection and protecting patients and medical care personnel.
Description
Technical Field
The invention relates to the technical field of medical treatment, in particular to a barrier material for a respiratory system.
Background
The establishment of artificial airways is a respiratory system and a respiratory circuit which provide respiratory gas or air for patients who are difficult to breathe spontaneously, as is well known, the artificial airways greatly weaken the regulation function of inhaled gas under physiological conditions and even make the function lose, the delivered gas or air cannot meet the proper temperature, humidity or cleanliness for effective use of the lungs of the patients, and artificial heating, humidification and filtration are required to protect the respiratory mucosa, cilia and glands to function normally, so that the risk of respiratory tract and lung infection is reduced. As a result, stringent material performance requirements are imposed on the gas flow filtering heat and moisture exchange between the respiratory system and the patient.
The conventional materials have poor water absorption and moisture retention capacity, and absorbed water is easy to exist in a loop in a liquid state, so that the traditional Chinese medicine has great breathing hidden trouble. The conventional material utilizes a net-shaped fiber structure or net charge adsorption, can filter most particles and pathogenic microorganisms attached to the particles, and still leaves part of the pathogenic microorganisms in a loop, thereby increasing the risk of lung infection of a patient.
Disclosure of Invention
The invention aims to provide a barrier material for a respiratory system, which solves the problems that the conventional materials in the background art have poor water absorption and moisture retention capacity, absorbed water is easy to exist in a liquid state in a loop, and the hidden trouble of breathing is large. The conventional material utilizes a net-shaped fiber structure or net charge adsorption, can filter most particles and pathogenic microorganisms attached to the particles, still has partial pathogenic microorganisms remained in a loop, and increases the risk of lung infection of a patient.
In order to achieve the purpose, the invention provides the following technical scheme: the barrier material for the respiratory system comprises a non-woven fabric air passage, wherein an adsorption wetting layer is arranged inside the non-woven fabric air passage, and the components of the adsorption wetting layer comprise antibacterial peptide and polyvinyl alcohol.
Preferably, the gram weight of the non-woven fabric air duct is 20g/m2-300g/m2。
Preferably, the density of the non-woven fabric air channel is 0.01g/cm3-0.10g/cm3。
Preferably, the gas resistance of the non-woven fabric gas channel is 0.1cmH2O 60L/min-5.0cmH2O 60L/min。
Preferably, the antimicrobial peptide and the polyvinyl alcohol are placed on the inner wall of the non-woven fabric airway.
Compared with the prior art, the invention has the beneficial effects that:
1) through the cooperation of non-woven fabrics air flue, absorption moist layer, have biological filtration concurrently and filter pathogenic microorganism with physics, can heat the breathing gas or the air of moisturizing again.
2) The polyvinyl alcohol is in a compact solid state before absorbing water, the long polymer chains of the polyvinyl alcohol are wound and curled mutually, a three-dimensional network structure is formed among chains, after the polyvinyl alcohol is in contact with water, a large amount of hydroxyl groups in the polyvinyl alcohol are combined with the water, the polymer chains are fully expanded, the three-dimensional network is expanded by many times, the three-dimensional network is full of absorbed water, and the polyvinyl alcohol has good water absorption and moisture retention capacity. The polyvinyl alcohol expands after absorbing water and being humidified, the fiber density is increased, the interception capability of the particles is improved, and the antibacterial peptide absorbs pathogenic microorganisms in a humidified state to achieve the effects of sterilization and antibiosis.
3) The polyvinyl alcohol and the antibacterial peptide are both polar materials, so that the biocompatibility is good; the polyvinyl alcohol contains a large amount of hydroxyl groups, and has good water absorption and moisture retention capacity; the polyvinyl alcohol expands after absorbing water, the fiber density is increased, and the physical filtration performance is improved; the antibacterial peptide kills pathogenic microorganisms in a humidified state, and has excellent biological filtration performance; preventing cross infection and protecting patients and medical care personnel.
Drawings
FIG. 1 is a schematic view of the structure of the present invention.
In the figure: 1 non-woven fabric air passage and 2 adsorption wetting layer.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example (b):
referring to fig. 1, the present invention provides a technical solution: the barrier material for the respiratory system comprises a non-woven fabric air passage 1, wherein an adsorption wetting layer 2 is arranged inside the non-woven fabric air passage 1, and the components of the adsorption wetting layer 2 comprise antibacterial peptide and polyvinyl alcohol.
Further, the gram weight of the non-woven fabric air passage 1 is 20g/m2-300g/m2。
Further, the density of the non-woven fabric air passage 1 is 0.01g/cm3-0.10g/cm3。
Further, the gas resistance of the non-woven fabric gas passage 1 was 0.1cmH2O 60L/min-5.0cmH2O 60L/min。
Further, the antibacterial peptide and the polyvinyl alcohol are placed on the inner wall of the non-woven fabric airway 1.
The principle of the barrier action of the antibacterial peptide/polyvinyl alcohol is as follows: the polyvinyl alcohol is in a compact solid state before absorbing water, the long polymer chains of the polyvinyl alcohol are wound and curled mutually, a three-dimensional network structure is formed among chains, after the polyvinyl alcohol is in contact with water, a large amount of hydroxyl groups in the polyvinyl alcohol are combined with the water, the polymer chains are fully expanded, the three-dimensional network is expanded by many times, the polyvinyl alcohol is full of absorbed water, and part of the absorbed water is in a water vapor state, so that the polyvinyl alcohol has good water absorption and moisture retention capacity. The polyvinyl alcohol expands after absorbing water and being humidified, the fiber density is increased, the interception capability of the particles is improved, and in addition, the antibacterial peptide absorbs pathogenic microorganisms in a humidified state, so that the effects of sterilization and antibiosis are achieved.
When the respirator exhales, the gas with the body temperature and the saturation humidity enters the inner side surface of the barrier material to be condensed, the heat stored in a steam state is released, and the barrier material collects the water vapor and the heat in the gas and filters pathogenic microorganisms and dust particles in the gas; when inhaling, the external dry air passes through the barrier material, takes away the water vapor and heat of the barrier material, and the humidified, warm and filtered air enters the lung. The reciprocating circulation can continuously utilize the heat and the humidity in the expiration to warm and humidify the inhaled gas, effectively filter the expired and inhaled gas and reduce the risk of lung infection of patients and the risk of cross infection in hospitals.
The material requirements are as follows: the alcoholysis degree of the polyvinyl alcohol is 90% or more.
The polyvinyl alcohol and the antibacterial peptide are both polar materials, so that the biocompatibility is good;
the polyvinyl alcohol contains a large amount of hydroxyl groups, and has good water absorption and moisture retention capacity.
The polyvinyl alcohol expands after absorbing water, the fiber density is increased, and the physical filtration performance is improved;
the antibacterial peptide kills pathogenic microorganisms in a humidified state, and has excellent biological filtration performance;
preventing cross infection and protecting patients and medical care personnel.
Performance: has the functions of biological filtration and physical filtration of pathogenic microorganisms, and can heat and moisturize respiratory gas or air.
While there have been shown and described the fundamental principles and essential features of the invention and advantages thereof, it will be apparent to those skilled in the art that the invention is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof; the present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein, and any reference signs in the claims are not intended to be construed as limiting the claim concerned.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A barrier material for the respiratory system, comprising a non-woven airway (1), characterized in that: the non-woven fabric air flue is characterized in that an adsorption wetting layer (2) is arranged inside the non-woven fabric air flue (1), and the components of the adsorption wetting layer (2) comprise antibacterial peptide and polyvinyl alcohol.
2. A barrier material for a respiratory system according to claim 1, wherein: the gram weight of the non-woven fabric air passage (1) is 20g/m2-300g/m2。
3. A barrier material for a respiratory system according to claim 1, wherein: the density of the non-woven fabric air passage (1) is 0.01g/cm3-0.10g/cm3。
4. A barrier material for a respiratory system according to claim 1, wherein: the gas resistance of the non-woven fabric gas passage (1) is 0.1cmH2O 60L/min-5.0cmH2O 60L/min。
5. A barrier material for a respiratory system according to claim 1, wherein: the antibacterial peptide and the polyvinyl alcohol are arranged on the inner wall of the non-woven fabric airway (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010859117.0A CN112057718A (en) | 2020-08-24 | 2020-08-24 | Barrier material for respiratory system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010859117.0A CN112057718A (en) | 2020-08-24 | 2020-08-24 | Barrier material for respiratory system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112057718A true CN112057718A (en) | 2020-12-11 |
Family
ID=73660034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010859117.0A Pending CN112057718A (en) | 2020-08-24 | 2020-08-24 | Barrier material for respiratory system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112057718A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114146276A (en) * | 2021-11-11 | 2022-03-08 | 中国人民解放军西部战区总医院 | Tracheal cannula nurses external member |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912658A (en) * | 2010-08-24 | 2010-12-15 | 吴涛 | Oxygen humidifying and conveying device |
| CN202314813U (en) * | 2011-11-03 | 2012-07-11 | 复旦大学附属眼耳鼻喉科医院 | Hasp-type trachea pad |
| CN204542566U (en) * | 2015-01-29 | 2015-08-12 | 上海市同仁医院 | Negative-pressure adsorption medical dressing |
| CN204734879U (en) * | 2015-04-20 | 2015-11-04 | 谷琼琼 | Traffic police is with preventing stealthy nasal obstruction of tail gas |
| CN105381502A (en) * | 2015-12-21 | 2016-03-09 | 杨雁 | Larva chrysomyiae liquid wound dressing and preparation method thereof |
| CN106492261A (en) * | 2016-10-09 | 2017-03-15 | 常州亚环环保科技有限公司 | A kind of preparation method of Medical composite membrane material |
| WO2017135192A1 (en) * | 2016-02-02 | 2017-08-10 | 株式会社村田製作所 | Drainage bag and suction system |
| CN108452418A (en) * | 2018-01-19 | 2018-08-28 | 广东药科大学 | A kind of tracheal catheter and its preparation method and application being loaded with antibacterial peptide MDC coatings |
-
2020
- 2020-08-24 CN CN202010859117.0A patent/CN112057718A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912658A (en) * | 2010-08-24 | 2010-12-15 | 吴涛 | Oxygen humidifying and conveying device |
| CN202314813U (en) * | 2011-11-03 | 2012-07-11 | 复旦大学附属眼耳鼻喉科医院 | Hasp-type trachea pad |
| CN204542566U (en) * | 2015-01-29 | 2015-08-12 | 上海市同仁医院 | Negative-pressure adsorption medical dressing |
| CN204734879U (en) * | 2015-04-20 | 2015-11-04 | 谷琼琼 | Traffic police is with preventing stealthy nasal obstruction of tail gas |
| CN105381502A (en) * | 2015-12-21 | 2016-03-09 | 杨雁 | Larva chrysomyiae liquid wound dressing and preparation method thereof |
| WO2017135192A1 (en) * | 2016-02-02 | 2017-08-10 | 株式会社村田製作所 | Drainage bag and suction system |
| CN106492261A (en) * | 2016-10-09 | 2017-03-15 | 常州亚环环保科技有限公司 | A kind of preparation method of Medical composite membrane material |
| CN108452418A (en) * | 2018-01-19 | 2018-08-28 | 广东药科大学 | A kind of tracheal catheter and its preparation method and application being loaded with antibacterial peptide MDC coatings |
Non-Patent Citations (2)
| Title |
|---|
| 安桂香等: "气管切开患者的护理", 《现代中西医结合杂志》 * |
| 薛超等: "国内临床气道湿化应用现状", 《齐鲁护理杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114146276A (en) * | 2021-11-11 | 2022-03-08 | 中国人民解放军西部战区总医院 | Tracheal cannula nurses external member |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Fang Xiangming Inventor after: Wu Kangping Inventor after: Sun Yaqi Inventor after: Fan Longxue Inventor after: Cheng Baoli Inventor after: Xiong Qixing Inventor after: Lin Ru Inventor before: Wu Kangping |
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| CB03 | Change of inventor or designer information | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20210528 Address after: Room 1202, unit 4, yuquanyuan, Shimao Lijing City, Xihu District, Hangzhou, Zhejiang 310000 Applicant after: Fang Xiangming Applicant after: Wu Kangping Address before: 313202 no.493, Huancheng North Road, Moganshan national high tech Zone, Huzhou City, Zhejiang Province Applicant before: ZHEJIANG LONGTERM MEDICAL TECHNOLOGY Co.,Ltd. |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201211 |
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| RJ01 | Rejection of invention patent application after publication |