CN112028768A - 一种草酸酯加氢制备乙醇酸酯的反应系统及方法 - Google Patents
一种草酸酯加氢制备乙醇酸酯的反应系统及方法 Download PDFInfo
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- CN112028768A CN112028768A CN202010933490.6A CN202010933490A CN112028768A CN 112028768 A CN112028768 A CN 112028768A CN 202010933490 A CN202010933490 A CN 202010933490A CN 112028768 A CN112028768 A CN 112028768A
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- micro
- hydrogenation
- reaction
- hydrogen
- oxalate
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- 238000005984 hydrogenation reaction Methods 0.000 title claims abstract description 83
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 42
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 title claims abstract description 33
- AEMRFAOFKBGASW-UHFFFAOYSA-M Glycolate Chemical compound OCC([O-])=O AEMRFAOFKBGASW-UHFFFAOYSA-M 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 19
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 52
- 239000001257 hydrogen Substances 0.000 claims abstract description 50
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 50
- 239000007795 chemical reaction product Substances 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims description 40
- 239000007789 gas Substances 0.000 claims description 27
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 15
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 15
- 239000002994 raw material Substances 0.000 claims description 13
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Natural products OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims description 12
- -1 glycolic acid ester Chemical class 0.000 claims description 12
- TZIHFWKZFHZASV-UHFFFAOYSA-N methyl formate Chemical compound COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 claims description 10
- 238000003860 storage Methods 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 7
- 150000002148 esters Chemical class 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- IEJIGPNLZYLLBP-UHFFFAOYSA-N dimethyl carbonate Chemical compound COC(=O)OC IEJIGPNLZYLLBP-UHFFFAOYSA-N 0.000 claims description 4
- 238000006473 carboxylation reaction Methods 0.000 claims description 2
- 238000006356 dehydrogenation reaction Methods 0.000 claims description 2
- 238000007599 discharging Methods 0.000 claims description 2
- LOMVENUNSWAXEN-UHFFFAOYSA-N Methyl oxalate Chemical compound COC(=O)C(=O)OC LOMVENUNSWAXEN-UHFFFAOYSA-N 0.000 abstract description 24
- 230000001965 increasing effect Effects 0.000 abstract description 6
- 239000012071 phase Substances 0.000 description 9
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- 239000003054 catalyst Substances 0.000 description 6
- 239000007791 liquid phase Substances 0.000 description 6
- 230000008569 process Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000006315 carbonylation Effects 0.000 description 3
- 238000005810 carbonylation reaction Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000005915 ammonolysis reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 description 1
- 229940106681 chloroacetic acid Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010933490.6A CN112028768A (zh) | 2020-09-08 | 2020-09-08 | 一种草酸酯加氢制备乙醇酸酯的反应系统及方法 |
| PCT/CN2020/122812 WO2022052222A1 (fr) | 2020-09-08 | 2020-10-22 | Système de réaction et procédé de préparation de glycolate par hydrogénation d'oxalate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010933490.6A CN112028768A (zh) | 2020-09-08 | 2020-09-08 | 一种草酸酯加氢制备乙醇酸酯的反应系统及方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112028768A true CN112028768A (zh) | 2020-12-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010933490.6A Pending CN112028768A (zh) | 2020-09-08 | 2020-09-08 | 一种草酸酯加氢制备乙醇酸酯的反应系统及方法 |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN112028768A (fr) |
| WO (1) | WO2022052222A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112717847A (zh) * | 2020-12-17 | 2021-04-30 | 南京延长反应技术研究院有限公司 | 一种环氧乙烷法制备乙二醇的微界面反应系统及方法 |
| WO2023165110A1 (fr) * | 2022-03-03 | 2023-09-07 | 南京延长反应技术研究院有限公司 | Système et procédé de préparation de micro-interface pour 1,4-butanediol |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101544539A (zh) * | 2009-04-28 | 2009-09-30 | 华烁科技股份有限公司 | 一种生产聚合级乙二醇并联产乙醇酸甲酯的方法 |
| CN104262152A (zh) * | 2014-09-16 | 2015-01-07 | 上海华谊（集团）公司 | 一种生产乙醇酸甲酯的方法 |
| CN210045215U (zh) * | 2019-01-29 | 2020-02-11 | 南京延长反应技术研究院有限公司 | 低压气液强化乳化床反应装置 |
| CN210079476U (zh) * | 2019-03-15 | 2020-02-18 | 南京延长反应技术研究院有限公司 | 一种微界面强化沸腾床加氢反应系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102649744B (zh) * | 2011-02-25 | 2015-01-07 | 中国石油化工股份有限公司 | 乙醇酸酯的生产方法 |
| CN104926657B (zh) * | 2014-03-17 | 2018-01-09 | 中国石油化工股份有限公司 | 草酸酯气相加氢合成乙醇酸酯的方法 |
| CN105348102B (zh) * | 2015-12-16 | 2018-02-23 | 西南化工研究设计院有限公司 | 一种草酸酯加氢制备乙醇酸酯的绝热反应系统及工艺 |
| CN109134258B (zh) * | 2017-06-28 | 2021-07-30 | 上海浦景化工技术股份有限公司 | 一种草酸二甲酯加氢制乙醇酸甲酯的产品分离工艺 |
| CN111359556A (zh) * | 2019-03-15 | 2020-07-03 | 南京延长反应技术研究院有限公司 | 一种微界面强化加氢反应系统 |
-
2020
- 2020-09-08 CN CN202010933490.6A patent/CN112028768A/zh active Pending
- 2020-10-22 WO PCT/CN2020/122812 patent/WO2022052222A1/fr active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101544539A (zh) * | 2009-04-28 | 2009-09-30 | 华烁科技股份有限公司 | 一种生产聚合级乙二醇并联产乙醇酸甲酯的方法 |
| CN104262152A (zh) * | 2014-09-16 | 2015-01-07 | 上海华谊（集团）公司 | 一种生产乙醇酸甲酯的方法 |
| CN210045215U (zh) * | 2019-01-29 | 2020-02-11 | 南京延长反应技术研究院有限公司 | 低压气液强化乳化床反应装置 |
| CN210079476U (zh) * | 2019-03-15 | 2020-02-18 | 南京延长反应技术研究院有限公司 | 一种微界面强化沸腾床加氢反应系统 |
Non-Patent Citations (1)
| Title |
|---|
| 张志炳 等: "多相反应体系的微界面强化简述", 《化工学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112717847A (zh) * | 2020-12-17 | 2021-04-30 | 南京延长反应技术研究院有限公司 | 一种环氧乙烷法制备乙二醇的微界面反应系统及方法 |
| WO2023165110A1 (fr) * | 2022-03-03 | 2023-09-07 | 南京延长反应技术研究院有限公司 | Système et procédé de préparation de micro-interface pour 1,4-butanediol |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022052222A1 (fr) | 2022-03-17 |
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Application publication date: 20201204 |