CN112013493A - Negative pressure sterile laminar flow transfer trolley - Google Patents

Abstract

The invention discloses a negative pressure sterile laminar flow transfer vehicle, wherein a power supply box body is arranged on a main box body, a working cavity is arranged at the middle lower part in the main box body, a gap is arranged between the outer wall of the working cavity and the inner wall of the main box body to form a return air channel, an air outlet is arranged at the lower part of the working cavity, an air inlet is arranged at the upper part of the working cavity, a uniform flow pore plate and a high-efficiency filter are sequentially arranged above the air inlet from bottom to top, an air outlet is arranged at the lower part of the high-efficiency filter, the air inlet at the upper part of the high-efficiency filter is connected with the air outlet at the lower part of. According to the invention, the working cavity is arranged in the main box body, and the gap is arranged between the working cavity and the main box body to form the return air channel, so that the air flow in the working cavity forms negative pressure circulation, and the air in the main box body cannot leak out through the gap, thereby avoiding the damage to the environment or workers.

Description

Negative pressure sterile laminar flow transfer trolley

Technical Field

The invention relates to a laminar flow transfer trolley mainly used in pharmaceutical places, in particular to a negative pressure sterile laminar flow transfer trolley.

Background

The laminar flow transfer trolley is a local purifying device mainly used in pharmaceutical places, carries a built-in power supply, is movable, provides a local high-cleanliness working environment, and has strong universality; the laminar flow transfer trolley can provide vertical unidirectional airflow, and the gas has a self-cleaning effect through efficient filtration in junior high schools; the laminar flow transfer trolley is always kept at a fixed airflow after being opened, so that cross contamination is prevented, and a working area is ensured to be in a clean environment.

The new GMP version imposes extremely strict implementation requirements on the transport of sterile materials, requiring the implementation of "isolation techniques". The aseptic material transfer technology runs through the whole aseptic medicine production flow. After the packaging materials (bottles, caps and stoppers) are sterilized, the packaging materials are moved from one room to another room or from one equipment to another equipment; transporting containers (barrels, tanks, bottles, pipelines and pumps) for production; the transportation of liquid medicine (medicinal powder) and the like are all parts of the new GMP key requirements and are one of key contents for implementing GMP modification in pharmaceutical factories. The laminar flow transfer trolley can better solve the problem of aseptic transfer of materials by implementing strict isolation technology on the materials. GMP is herein called GOOD MANUFACTURING PRICICES, and means "production quality control Specification" or "GOOD practice Specification" or "GOOD MANUFACTURING Standard".

The laminar flow transfer trolley makes up for the cleanliness requirements of certain spaces which cannot be met by fixed laminar flow hoods, FFUs and other equipment. The pharmaceutical industry requires that "the drug must avoid direct or indirect contact with the operator as much as possible". The laminar flow transfer trolley has the advantages that the pollution of personnel to medicines and clean rooms is avoided, the harm of harmful and toxic medicines to personnel is avoided, the laminar flow transfer trolley is widely applied to scientific research and production departments of local clean environments needing to flow in the object moving process in the fields of medicines, biology, chemical engineering, electronics, precise instruments, food and the like, and the pollution of clean objects to the outside in the moving process can be effectively avoided. The FFU is a shorthand of a Fan Filter Unit, namely a Fan Filter Unit, is a self-powered air supply Filter device, and is a modular tail end air supply device with a filtering effect.

The working principle of the traditional laminar flow transfer trolley is as follows: air is purified by the high-efficiency filtering fan unit and flows through the working platform from top to bottom, medicine is purified and protected, an air protection surface is formed between the periphery of the working platform and a vertical curtain (or toughened glass), positive pressure difference is formed between the inside and the outside of the laminar flow vehicle, air in an external low-level area is prevented from polluting a high-level area in the laminar flow vehicle, but the working cavity is inevitably subjected to the conditions of poor sealing, unstable air flow and the like, so that polluted gas in the working cavity is leaked to the outside, the leakage is a dangerous point, and the environment or workers can be injured; in addition, the sealing effect between the high-efficiency air filter and the box body frame of the traditional laminar flow transfer trolley is not ideal enough, so that harmful virus particles in the air can enter the working cavity at the lower part through gaps, and the cleanliness in the working cavity is reduced.

Disclosure of Invention

The invention aims to solve the problems and provide a negative pressure sterile laminar flow transfer trolley with a negative pressure in a working cavity.

The invention realizes the purpose through the following technical scheme:

a negative-pressure sterile layer transfer trolley comprises a main box body, a power supply box body, an FFU fan, a high-efficiency filter and a uniform flow pore plate, wherein wheels are installed below a bottom plate of the main box body, the power supply box body is arranged on the upper surface of the main box body, a working cavity is arranged at the middle lower part in the main box body, a gap is formed between the outer wall of the working cavity and the inner wall of the main box body to form a return air channel, an air outlet is formed in the lower part of the working cavity, an air inlet is formed in the upper part of the working cavity, the uniform flow pore plate and the high-efficiency filter are sequentially installed above the air inlet from bottom to top, an air outlet is formed in the lower part of the high-efficiency filter, the air inlet in the upper part of the high-efficiency filter is connected with the air. The FFU fan is a fan adopted by a fan filter unit and has the characteristic of variable air volume.

Further, high efficiency filter includes high efficiency filter core and filter core shell, high efficiency filter core is arranged in the filter core shell, the upper portion and the lower part of filter core shell are connected with the box frame respectively, the upper portion of filter core shell is equipped with the last seal of epirelief, the upper portion of going up the seal is equipped with the seal groove, be equipped with mechanical seal adhesive tape in going up the seal groove, the following in close contact with of mechanical seal adhesive tape and backing plate, the backing plate with the box frame is connected, the lower part of filter core shell is equipped with the bellied lower seal in the outside, the upper portion of lower seal is equipped with down the seal groove, down the seal inslot is filled with jelly glue and the lateral buckling back of closing plate and arranges in the jelly glue, the opposite side of closing plate with.

The invention has the beneficial effects that:

according to the invention, the working cavity is arranged in the main box body, a gap is arranged between the working cavity and the main box body to form a return air channel, the FFU fan sends air into the working cavity after passing through the high-efficiency filter and the uniform flow pore plate, the air enters the air inlet of the FFU fan after passing through the lower air outlet of the working cavity and the return air channel, so that the air flow in the working cavity forms negative pressure circulation, the air in the main box body cannot leak out through the gap, and the harm to the environment or workers is avoided; through set up the mechanical seal adhesive tape on upper portion and the jelly glue of lower part between high efficiency filter and box frame, show and improve the sealed effect between high efficiency filter and the box frame, effectively prevented in the harmful virus granule in the air gets into the work cavity of lower part through the clearance between high efficiency filter and the box frame, guaranteed to keep high cleanliness in the work cavity.

Drawings

FIG. 1 is a schematic front view of a negative pressure sterile laminar flow transfer vehicle according to the present invention;

FIG. 2 is an enlarged schematic view of the FFU fan, HEPA filter and uniform flow orifice plate of the present invention;

fig. 3 is an enlarged view of "a" in fig. 2.

Detailed Description

The invention will be further described with reference to the accompanying drawings in which:

as shown in fig. 1, 2 and 3, the negative pressure sterile laminar flow trolley of the invention comprises a main box body 12 and a power supply box body 8, the FFU fan 9, the high-efficiency filter 10 and the uniform flow pore plate 14, wheels 16 are installed below a bottom plate 15 of a main box body 12, a power supply box body 8 is arranged on the main box body 12, a working cavity 11 is arranged at the middle lower part in the main box body 12, a gap is formed between the outer wall of the working cavity 11 and the inner wall of the main box body 12 to form a return air channel 13, an air outlet is formed at the lower part of the working cavity 11, an air inlet is formed at the upper part of the working cavity 11, the uniform flow pore plate 14 and the high-efficiency filter 10 are sequentially installed above the air inlet from bottom to top, an air outlet is formed at the lower part of the high-efficiency filter 10, the air inlet at the upper part of the high-efficiency filter 10 is connected with the air; high efficiency filter 10 includes high efficiency filter core 20 and filter core shell 21, and in high efficiency filter core 20 placed filter core shell 21 in, the upper portion and the lower part of filter core shell 21 were connected with box frame (not shown in the figure) respectively, and the upper portion of filter core shell 21 was equipped with the last seal 19 of epirelief, and the upper portion of going up seal 19 is equipped with the seal groove, go up and be equipped with mechanical seal adhesive tape 18 in the seal groove, the following in close contact with of mechanical seal adhesive tape 18 and backing plate 17, backing plate 17 with the box frame is connected, and the lower part of filter core shell 21 is equipped with outside bellied lower seal 24, and the upper portion of lower seal 24 is equipped with down the seal groove, down in seal groove intussuseption is filled with jelly 23 and seal plate 22 after buckling place jelly 23 in.

Also shown in fig. 1 are a DOP dust emission detecting port 1, a differential pressure display 2, a power switch 3, a touch panel 5, a start button 6 and a door opening button 7, which are conventional structures, provided on a panel of a power cabinet 8. DOP is a abbreviation of Dioctyl Phthalate, namely Dioctyl Phthalate, is also called aerosol for short, is an organic ester compound, and is a common plasticizer.

As shown in fig. 1-3, the working principle of the negative pressure sterile laminar flow transfer vehicle of the present invention is as follows:

the transfer trolley is mainly used for transferring toxic and harmful articles and preventing the harm to personnel and environment. The air passes through the FFU fan 9, laminar flow is formed from top to bottom after being purified by the high-efficiency filter 10, the clean air flows through the uniform flow pore plate 14 and transports articles, an air protection surface is formed in the working cavity 11, the mixed gas flowing through the articles enters the air return channel 13 through the air outlets on two sides of the lower part of the working cavity 11 and then enters the air inlet of the FFU fan 9 again, so that a reciprocating circulation process is formed, virus particles, dust and the like in the mixed air flow through the high-efficiency filter 10 to be filtered, and the filtered clean air enters the working cavity 11 again. Under the action of the high-efficiency filter 10, the inside of the working cavity 11 always forms a negative pressure state with the outside, and the air inside cannot leak out through the gap. In the material transportation process, can kill the harmful virus of inside through the ultraviolet ray or VHP that set up to through the continuous circulation purification of air, reach work cavity 11 self-purification purpose and aseptic effect.

A Siemens smart st20 controller is configured in the equipment to realize intelligent control; the door is opened and interlocked with the FFU fan 9: the FFU fan 9 can be started after the door is locked and the time delay is 3s after the sample is placed in the opened door, and the FFU fan 9 cannot be started when the door is opened. After the FFU fan 9 is closed, the lofting door can be opened after the time delay of 10S; the delay time may be set by the touch screen 5.

The above embodiments are only preferred embodiments of the present invention, and are not intended to limit the technical solutions of the present invention, so long as the technical solutions can be realized on the basis of the above embodiments without creative efforts, which should be considered to fall within the protection scope of the patent of the present invention.

Claims (2)

1. The utility model provides a no aseptic laminar flow transfer car (buggy) of negative pressure, includes main tank body, power supply box body, FFU fan, high efficiency filter and even orifice plate that flows, install the wheel below the bottom plate of main tank body, the power supply box body is located above the main tank body, its characterized in that: the utility model discloses a high efficiency filter, including main box, work cavity, even flow pore plate and high efficiency filter, well lower part in the main box is equipped with the work cavity, the outer wall of work cavity with be equipped with the clearance between the inner wall of main box and form the return air passageway, the lower part of work cavity is equipped with the air outlet, the upper portion of work cavity is equipped with the air intake and the top of this air intake is installed from bottom to top in proper order even flow pore plate with high efficiency filter, high efficiency filter's lower part is equipped with the air outlet, high efficiency filter upper portion the air intake with the air outlet of FFU fan lower part is connected, the upper.

2. The negative-pressure sterile laminar flow transfer car (buggy) of claim 1, wherein: the high efficiency filter includes high efficiency filter core and filter core shell, high efficiency filter core arranges in the filter core shell, the upper portion and the lower part of filter core shell are connected with the box frame respectively, the upper portion of filter core shell is equipped with the last seal of epirelief, the upper portion of going up the seal is equipped with the seal groove, be equipped with mechanical sealing adhesive tape in the seal groove, below in close contact with of mechanical sealing adhesive tape and backing plate, the backing plate with the box frame is connected, the lower part of filter core shell is equipped with the bellied lower seal in the outside, the upper portion of seal is equipped with down the seal groove down, down the seal groove intussuseption be filled with jelly glue and the lateral buckling back of closing plate arrange in the jelly glue, the opposite side of closing plate with the.

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