CN112007108A - Traditional Chinese medicine formula for treating and preventing heart failure - Google Patents

Traditional Chinese medicine formula for treating and preventing heart failure Download PDF

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Publication number
CN112007108A
CN112007108A CN201910453219.XA CN201910453219A CN112007108A CN 112007108 A CN112007108 A CN 112007108A CN 201910453219 A CN201910453219 A CN 201910453219A CN 112007108 A CN112007108 A CN 112007108A
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traditional chinese
chinese medicine
mulberry
ginseng
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刘仪龙
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine formula for treating and preventing heart failure. The invention is prepared from the following raw materials in parts by weight: 10-100 parts of ginseng, 10-80 parts of phellodendron amurense, 8-60 parts of lucid ganoderma, 5-40 parts of polygonatum odoratum, 8-80 parts of angelica sinensis, 10-60 parts of mulberry and 6-30 parts of ginkgo. The raw materials are scientifically proportioned according to a certain proportion through experimental research, so that the traditional Chinese medicine composition has the functions of coordinating the functions of the five internal organs, warming and expanding contracted blood vessels, awakening most dormant myocardial cells and increasing the resistance of the five internal organs so as to treat the heart failure.

Description

Traditional Chinese medicine formula for treating and preventing heart failure
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating and preventing heart failure.
Background
Heart failure, the terminal stage of all cardiovascular diseases, is known as the last "battlefield" of the cardiovascular field. With the increasing aging of the population in China, the incidence of chronic diseases such as coronary heart disease, hypertension and the like is on the rise, the improvement of the medical level prolongs the life cycle of heart disease patients, and the incidence and mortality of heart failure are on the obvious rise. At present, the prevalence rate of heart failure in China is 0.9%, and about 1000 ten thousand heart failure patients exist.
At present, the western medicine mainly adopts medicines for treating heart failure. However, the patients cannot tolerate the side effects of western medicines, and the medicines can only maintain and relieve the state of illness, but the state of illness still attacks repeatedly and is difficult to cure for a long time. The traditional Chinese medicine considers that most heart failure patients gradually have 'nutrient deficiency' due to the imbalance of yin and yang caused by the increase of age or other special reasons, the damage of five internal organs, the deficiency of kidney essence, the failure of qi and blood generation and the deficiency of qi and blood. Therefore, the heart failure can be fundamentally cured only by carrying out syndrome differentiation comprehensive treatment of the traditional Chinese medicine.
Disclosure of Invention
The invention provides a traditional Chinese medicine formula for preventing and treating heart failure, which has the functions of coordinating the functions of the five internal organs, warming and expanding contracted blood vessels, awakening most dormant myocardial cells and increasing the resistance of the five internal organs so as to treat heart failure. The formula contains 7 traditional Chinese medicines: ginseng, phellodendron amurense, ganoderma lucidum, polygonatum odoratum, angelica, mulberry and ginkgo.
The traditional Chinese medicine formula comprises the following components in parts by weight: 10-60 parts of ginseng, 10-60 parts of phellodendron amurense, 6-50 parts of lucid ganoderma, 5-25 parts of polygonatum odoratum, 8-50 parts of angelica sinensis, 10-50 parts of mulberry and 6-30 parts of ginkgo.
The traditional Chinese medicine formula preferably comprises the following components in parts by weight: 10 parts of ginseng, 10 parts of phellodendron amurense, 8 parts of ganoderma lucidum, 5 parts of polygonatum odoratum, 8 parts of angelica, 10 parts of mulberry and 6 parts of ginkgo.
The important formula of the heart failure provided by the invention can be decocted in water for oral administration, and can also be prepared into a traditional Chinese medicine ointment pill for oral administration.
Is decocted in water for oral administration: the heart failure treatment is carried out by taking one dose every day, 3 days are taken as a treatment course, the medicine is taken 6 times a day, the medicine taking frequency after 3 days is determined according to the state of the illness, and the dosage can be reduced or the dosage can be reduced if the illness state is stable.
The traditional Chinese medicine pill is taken orally: the treatment of heart failure is carried out 6 times a day, 8-10 g/time is carried out once, 3 days are a treatment course, the number of times of taking medicine after 3 days is determined according to the state of illness, and the treatment course can be reduced to 2 times a day if the illness state is stable.
The traditional Chinese medicine formula provided by the invention can effectively prevent and treat heart failure, has good treatment effect and strong pertinence, can show special effect one to two hours after the heart failure attack, and is convenient for clinical and individual use. The traditional Chinese medicine formula has easily available raw materials, simple method and more than ninety percent of effective rate.
Detailed Description
The present invention will be described in further detail with reference to specific embodiments, but the embodiments of the present invention are not limited thereto.
Example 1
Weighing the following traditional Chinese medicines: 100g of ginseng, 80g of phellodendron amurense, 80g of lucid ganoderma, 40g of polygonatum odoratum, 80g of angelica, 60g of mulberry and 30g of ginkgo. The composition is decocted in water for oral administration, 1 dose per day, and is taken in 6 times, once every three hours.
Example 2
Weighing the following traditional Chinese medicines: 30g of ginseng, 40g of phellodendron amurense, 20g of lucid ganoderma, 15g of polygonatum odoratum, 15g of angelica, 40g of mulberry and 16g of ginkgo. Pulverizing and sieving the powder with a 150-mesh sieve to prepare the traditional Chinese medicine pills for oral administration, wherein the dosage is 10-20 g/time, and 4 times a day.
Example 3
Weighing the following traditional Chinese medicines: 30g of ginseng, 20g of phellodendron amurense, 20g of lucid ganoderma, 10g of polygonatum odoratum, 15g of angelica, 30g of mulberry and 15g of ginkgo. Pulverizing and sieving the powder with a 150-mesh sieve to prepare the traditional Chinese medicine pills for oral administration, wherein the dosage is 10-12 g/time, and the dosage is 3 times per day.
Example 4
Weighing the following traditional Chinese medicines: 50g of ginseng, 60g of phellodendron amurense, 40g of lucid ganoderma, 40g of angelica, 30g of mulberry and 25g of ginkgo. The composition is decocted in water for oral administration, 1 dose per day, and concentrated for administration in 4 times.
Example 5
Weighing the following traditional Chinese medicines: 60g of ginseng, 80g of phellodendron amurense, 60g of ganoderma lucidum, 50g of angelica, 60g of mulberry and 40g of ginkgo. Aoyao paste is made into pill, 1 dose per day, and is concentrated and administered in 6 times.
And (3) clinical trials:
typical case 1
Chen is old, male, age 76, suffered from coronary heart disease for 6 years, left atrium peripheral vessel obstruction, and built-in stent. After the cold, the patient feels bad at the chest and mouth, and has heart failure, and western medicines are taken after the patient enters a hospital, but the effect is not obvious. The traditional Chinese medicine is taken later, the patient is out of bed for 3 days, and the condition is stable after 6 days. After taking the medicine for 5 treatment courses, no heart failure occurs again.
Typical case 2
Wangzhi, female, age 52, is hospitalized with heart failure due to pulmonary heart disease and coronary artery occlusion, but the treatment is not ideal. After the patient is discharged from hospital, the patient can walk by himself after 7 days, the condition is stable after the patient takes the medicine for 9 days, and the patient does not have heart failure until now after 3 treatment courses.
Typical case 3
Liza, male, age 54, with hypertension, coronary heart disease. Sudden heart failure and difficulty in walking due to cold and the surrounding environment. The patient can get better after taking the formula for treatment in 3 days, and can walk by oneself in 4 days. After continuously taking for 4 courses, no heart failure occurs until now.

Claims (4)

1. The traditional Chinese medicine composition for treating and preventing heart failure is characterized by being prepared from the following raw materials in parts by weight:
10-100 parts of ginseng, 10-80 parts of phellodendron amurense, 8-60 parts of lucid ganoderma, 5-40 parts of polygonatum odoratum, 8-80 parts of angelica sinensis, 10-60 parts of mulberry and 6-30 parts of ginkgo.
2. The traditional Chinese medicine formula for treating heart failure as claimed in claim 1, wherein the traditional Chinese medicine composition comprises the following ten schemes:
the first scheme is as follows: 10 parts of ginseng, 10 parts of phellodendron amurense, 8 parts of ganoderma lucidum, 5 parts of polygonatum odoratum, 8 parts of angelica, 10 parts of mulberry and 6 parts of ginkgo seed;
scheme II: 100 parts of ginseng, 80 parts of phellodendron amurense, 80 parts of ganoderma lucidum, 40 parts of polygonatum odoratum, 80 parts of angelica, 60 parts of mulberry and 30 parts of ginkgo;
the third scheme is as follows: 30 parts of ginseng, 40 parts of phellodendron amurense, 20 parts of ganoderma lucidum, 15 parts of polygonatum odoratum, 15 parts of angelica, 40 parts of mulberry and 16 parts of ginkgo;
and the scheme is as follows: 30 parts of ginseng, 20 parts of phellodendron amurense, 20 parts of ganoderma lucidum, 10 parts of polygonatum odoratum, 15 parts of angelica, 30 parts of mulberry and 15 parts of ginkgo;
and a fifth scheme: 60 parts of ginseng, 60 parts of phellodendron amurense, 50 parts of ganoderma lucidum, 25 parts of polygonatum odoratum, 50 parts of angelica, 50 parts of mulberry and 36 parts of ginkgo seed;
scheme six: 40 parts of ginseng, 40 parts of phellodendron amurense, 30 parts of ganoderma lucidum, 20 parts of polygonatum odoratum, 30 parts of angelica, 40 parts of mulberry and 25 parts of ginkgo;
the scheme is seven: 30 parts of ginseng, 20 parts of phellodendron amurense, 20 parts of ganoderma lucidum, 15 parts of polygonatum odoratum, 20 parts of angelica, 20 parts of mulberry and 12 parts of ginkgo;
and the eighth scheme is as follows: 20 parts of ginseng, 15 parts of phellodendron amurense, 20 parts of ganoderma lucidum, 10 parts of polygonatum odoratum, 15 parts of angelica, 20 parts of mulberry and 20 parts of ginkgo seed;
the scheme is nine: 50 parts of ginseng, 60 parts of phellodendron amurense, 40 parts of ganoderma lucidum, 40 parts of angelica, 30 parts of mulberry and 25 parts of ginkgo seed;
and a scheme ten: 60 parts of ginseng, 80 parts of phellodendron chinense, 60 parts of ganoderma lucidum, 50 parts of angelica, 60 parts of mulberry and 40 parts of ginkgo.
3. The traditional Chinese medicine formula for treating heart failure according to claim 2, which can be decocted in water for oral administration.
4. The traditional Chinese medicine formula for treating heart failure according to claim 2, wherein the traditional Chinese medicine formula can be prepared into traditional Chinese medicine ointment pills for oral administration.
CN201910453219.XA 2019-05-28 2019-05-28 Traditional Chinese medicine formula for treating and preventing heart failure Pending CN112007108A (en)

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Application Number Priority Date Filing Date Title
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860874A (en) * 2014-04-11 2014-06-18 李明 Traditional Chinese medicine for treating chronic heart failure with sexual dysfunction

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860874A (en) * 2014-04-11 2014-06-18 李明 Traditional Chinese medicine for treating chronic heart failure with sexual dysfunction

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
关启文等: "益心汤治疗顽固性心衰10例", 《云南中医中药杂志》 *

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Application publication date: 20201201