CN112005961B - Automatic change condition position preference class animal behavior experimental apparatus - Google Patents
Automatic change condition position preference class animal behavior experimental apparatus Download PDFInfo
- Publication number
- CN112005961B CN112005961B CN202010711434.8A CN202010711434A CN112005961B CN 112005961 B CN112005961 B CN 112005961B CN 202010711434 A CN202010711434 A CN 202010711434A CN 112005961 B CN112005961 B CN 112005961B
- Authority
- CN
- China
- Prior art keywords
- experiment
- chamber
- push plate
- area
- blocking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/02—Breeding vertebrates
Abstract
The embodiment of the invention provides an automatic condition position preference type animal behavior experiment device which comprises a device main body, a blocking mechanism, a driving mechanism, a punishing mechanism and an experiment controller, wherein the device main body is provided with an experiment preparation area, an experiment area and a reward applying area; the blocking mechanism has a blocking state and a releasing state; the driving mechanism is used for driving animals to move in the experimental area; the punishment mechanism is used for applying punishment to the animals in the experimental area; the blocking mechanism, the driving mechanism and the punishing mechanism are electrically connected with the experiment controller. The automatic condition position preference animal behavior experimental device provided by the embodiment of the invention can realize the conversion of the position of the detected animal without manual intervention by automatically controlling the blocking mechanism and the driving mechanism; and the application of the reward and the punishment is set before the experiment through the experiment controller, so that automatic multiple continuous experiments can be realized, and the influence of manual intervention on the experiment result is reduced.
Description
Technical Field
The invention relates to the technical field of animal experiment equipment, in particular to an automatic condition and position preference animal behavior experiment device.
Background
The animal behavior experimental device is widely applied to the fields of psychology, education, zootechnics and other subjects. Substance abuse is one of the major problems facing today's society, and the various addictive substances/drugs cause serious damage and burden to the abuser's physiology, psychology, and its families and society. The conditional position preference animal experiment device is a main means for carrying out animal addiction behaviors. Such experiments study addiction mechanism, preventive strategy and find therapeutic targets, etc. by establishing reward and punishment mechanism, by observing the stay and shuttle behavior of animals at different positions in the experimental device.
Due to the large difference of animal behavior experiments, special experimental equipment is often needed for different animal behavior experiments. At present, the research on animal addiction behaviors mainly adopts a conditional position preference type experimental device, namely, artificially setting areas with different experimental conditions, and observing behaviors generated by the stay of animals in different areas and the movement of the animals among the areas, wherein rewards mainly comprise medicines, foods and the like, and punishment stimulation mainly comprises electric shock and the like. The most degree of automation of current condition position preference experimental apparatus is lower, in continuous experimentation, needs the experimenter to artificially shift the animal between the region of difference, because the time that this type of experiment often lasts is longer, so can cause the higher problem of the human cost of experiment, also can have the restriction to the experimental design.
Disclosure of Invention
The embodiment of the invention provides an automatic condition and position preference animal behavior experiment device, which is used for solving the problems that most of the existing condition and position preference experiment devices are low in automation degree, and experimenters are required to manually transfer animals among different regions.
The embodiment of the invention provides an automatic conditional position preference animal behavior experimental device, which comprises:
the experiment device comprises a device main body, a detection device and a control device, wherein an experiment preparation area, an experiment area and a reward application area are formed in the device main body, and the experiment area is arranged between the experiment preparation area and the reward application area at intervals;
a blocking mechanism provided on the apparatus main body, the blocking mechanism having a blocking state of blocking the animal from entering the experiment area from the experiment preparation area, and a release state opposite to the blocking state;
the driving mechanism is arranged on the device main body and is used for driving animals to move in the experimental area;
a punishment mechanism arranged on the device body and used for applying punishment to the animals in the experimental area; and the number of the first and second groups,
the experiment controller set up in the device main part, block mechanism, drive the mechanism and punishment mechanism all with experiment controller electric connection.
According to the automatic conditional position preference type animal behavior experiment device provided by the embodiment of the invention, the device main body is provided with a first accommodating cavity, a second accommodating cavity and a third accommodating cavity, and the first accommodating cavity, the second accommodating cavity and the third accommodating cavity respectively form the experiment preparation area, the experiment area and the reward application area;
the first chamber that holds with the third holds the chamber and is to extend the setting along the first direction, the second holds the chamber and extends the setting for following the second direction, the first chamber that holds with the third holds the chamber and is located respectively the second holds the chamber and is in both sides in the second direction, the first chamber that holds with the third holds the chamber and is in same one end in the first direction communicates respectively the second holds the chamber and is in the both ends of second direction, wherein, the first direction with the second direction is crossing.
According to the automatic conditional position preference type animal behavior experiment device provided by the embodiment of the invention, one of the first accommodating cavity and the second accommodating cavity is provided with a gate at the communication position of the first accommodating cavity and the second accommodating cavity, and the other accommodating cavity is communicated with the gate through the gate;
the blocking mechanism comprises a blocking piece and a driving assembly, the blocking piece is movably arranged at the gate along the first direction, the blocking piece is used for opening and closing the gate, and the driving assembly is used for driving the blocking piece to move along the first direction.
According to the automatic conditional position preference type animal behavior experiment device provided by the embodiment of the invention, the driving assembly and the blocking piece are arranged on the outer cavity wall of the first accommodating cavity; and/or the presence of a gas in the gas,
the driving assembly is located on one side of the gate in a third direction, the driving assembly comprises a first driving motor and a first lead screw structure, the first driving motor and the first lead screw structure are both arranged along the first direction, a rotating shaft of the first driving motor is connected with one end of a lead screw of the first lead screw structure, a lead screw nut of the first lead screw structure is connected with the blocking piece through a first connecting piece, and the first direction, the second direction and the third direction are intersected in pairs; and/or the presence of a gas in the gas,
the blocking piece is a gate, and the direction of the gate is the second direction; and/or the presence of a gas in the gas,
the blocking mechanism further comprises a first limit switch, and the first limit switch is used for limiting the blocking piece in the moving stroke of the blocking piece.
According to the automatic conditional position preference type animal behavior experiment device provided by the embodiment of the invention, the device body is provided with a second accommodating cavity extending along a second direction, and the second accommodating cavity forms the experiment area; the driving mechanism comprises:
the push plate is movably arranged in the second accommodating cavity along the second direction, and the direction of the push plate is the second direction; and the number of the first and second groups,
and the push plate driving component is used for driving the push plate to move along the second direction.
According to the automatic condition position preference animal behavior experimental device provided by the embodiment of the invention, the push plate is arranged in a hollow manner; and/or the presence of a gas in the gas,
the push plate driving assembly is positioned on one side of the push plate in a third direction and is arranged on the outer cavity wall of the second accommodating cavity, a sliding groove extending along the second direction is arranged on the cavity wall of the second accommodating cavity in a penetrating mode, a second connecting piece is installed at the sliding groove in a sliding mode, two ends of the second connecting piece in the third direction are respectively connected with the push plate and the push plate driving assembly, and the second direction is intersected with the third direction; and/or the presence of a gas in the gas,
the push plate driving assembly comprises a second driving motor and a second lead screw structure, the second driving motor and the second lead screw structure are arranged along the second direction, a rotating shaft of the second driving motor is connected with one end of a lead screw of the second lead screw structure, and a lead screw nut of the second lead screw structure is connected with the push plate through a second connecting piece; and/or the presence of a gas in the gas,
the driving mechanism further comprises a second limit switch, and the second limit switch is used for limiting the push plate in the moving stroke of the push plate.
According to an embodiment of the invention, the automatic conditional position preference animal behavior experiment device comprises an experiment area, a punishment mechanism and a reward application area, wherein the experiment area is provided with a bearing surface for bearing an animal, and the punishment mechanism comprises an electric shock plate which is arranged on the bearing surface and is close to the reward application area.
According to one embodiment of the invention, the automatic condition position preference type animal behavior experiment device further comprises a prompt lamp which is arranged on the device main body and is electrically connected with the experiment controller, and the prompt lamp comprises a punishment prompt lamp and/or an experiment starting prompt lamp.
According to one embodiment of the invention, the automatic conditional position preference type animal behavior experiment device further comprises a monitoring mechanism which is arranged on the device main body and electrically connected with the experiment controller, and the monitoring mechanism is used for monitoring the position and the movement speed of the animal in the experiment area.
According to the automatic conditional position preference type animal behavior experiment device provided by the embodiment of the invention, the device body is provided with a second accommodating cavity extending along a second direction, and the second accommodating cavity forms the experiment area;
the second holds the chamber and runs through and is provided with a plurality of edges second direction interval arrangement mounting hole, monitoring mechanism including set up respectively in a plurality of proximity switch of a plurality of mounting hole department.
The automatic condition position preference animal behavior experimental device provided by the embodiment of the invention can realize the conversion of the position of the detected animal without manual intervention by automatically controlling the blocking mechanism and the driving mechanism; and the application of the reward and the punishment is set before the experiment through the experiment controller, so that automatic multiple continuous experiments can be realized, and the influence of manual intervention on the experiment result is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and those skilled in the art can also obtain other drawings according to the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of an automated conditional location-preference animal behavior experiment apparatus provided in an embodiment of the present invention;
FIG. 2 is a schematic view of a planar structure of FIG. 1;
FIG. 3 is another schematic plan view of the structure of FIG. 1;
fig. 4 is a schematic circuit configuration diagram of the control section in fig. 1.
Reference numerals:
100: an automatic conditional position preference animal behavior experimental device; 1: a device main body; 11: an experimental preparation area; 12: an experimental area; 13: a reward application zone; 2: a blocking mechanism; 21: a blocking member; 22: a first drive motor; 23: a first lead screw structure; 24: a first connecting member; 25: a first limit switch; 3: a driving mechanism; 31: pushing the plate; 32: a second drive motor; 33: a second lead screw structure; 34: a second limit switch; 4: a penalty mechanism; 41: an electric shock plate; 5: an experiment controller; 51: punishment prompting lamps; 52: an experiment start prompting lamp; 53: a motor stroke controller; 54: a first motor driver; 55: a second motor driver; 6: a monitoring mechanism; 61: a proximity switch; 7: an interactive touch screen; 8: a power source.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
An embodiment of the present invention provides an automated conditional locus preferential type animal behavior experimental apparatus, as shown in fig. 1 and fig. 2, an automated conditional locus preferential type animal behavior experimental apparatus 100 (hereinafter, referred to as an automated experimental apparatus 100) includes an apparatus main body 1, a blocking mechanism 2, a driving mechanism 3, a punishment mechanism 4, and an experiment controller 5.
As shown in fig. 1 and 2, the apparatus body 1 is formed with an experiment preparation area 11, an experiment area 12, and a reward application area 13, and the experiment area 12 is disposed at intervals between the experiment preparation area 11 and the reward application area 13. Before the start of an experiment, the tested animal is placed in the experiment preparation area 11, the reward is placed in the reward application area 13, and the reward application area 13 is spatially isolated from the experiment preparation area 11, wherein the reward may include a foreign animal, a medicine, food, and the like, for example, when the tested animal is a male mouse, the reward may be a female mouse. As a result of the reward, the animal enters the test area 12 and moves towards the reward application area 13, sets a penalty event in the test area 12, and records the movement of the animal in the test area 12 during the course of the test. At the end of the experiment, the animals are returned to the preparation area 11 and the experiment is ended.
Specific patterns for the experiment preparation area 11, the experiment area 12, and the reward applying area 13 may be set according to actual needs, for example, as shown in fig. 1 and 2, in the present embodiment, the apparatus main body 1 is provided with a first accommodating chamber, a second accommodating chamber, and a third accommodating chamber, which form the experiment preparation area 11, the experiment area 12, and the reward applying area 13, respectively; the first chamber and the third chamber that holds are along the first direction extension setting, and the second holds the chamber and extends the setting for following the second direction, and first chamber and the third that holds are located the second respectively and hold the both sides of chamber in the second direction, and first chamber and the third that hold communicate the second respectively and hold the both ends of chamber in the second direction with the one end in the first direction in the chamber, and wherein, first direction is crossing with the second direction. Thus, the whole automatic experimental device 100 is in a cage type and can be used for conditional position preference type experiments of animals such as mice and the like.
As shown in fig. 1 and 3, the blocking mechanism 2 is provided on the apparatus main body 1, and the blocking mechanism 2 has a blocking state of blocking the animal from entering the experiment preparation area 11 into the experiment area 12, and a release state opposite to the blocking state. Before the beginning of a test, the animal is in the test preparation area 11, and the blocking mechanism 2 is in a blocking state; at the start of the experiment, the blocking mechanism 2 is switched to the release state and the animal can move from the preparation area 11 to the experimental area 12.
Specifically, as shown in fig. 1 and 3, in the present embodiment, one of the first accommodating chamber and the second accommodating chamber is provided with a gate at a communication position of the two (not shown in the drawings, in the present embodiment, one end of the second accommodating chamber close to the first accommodating chamber is open, and the gate is provided on a chamber wall of the first accommodating chamber) for communicating the other through the gate; the blocking mechanism 2 includes a blocking member 21 and a driving component, the blocking member 21 is movably disposed at the gate along the first direction, the blocking member 21 is configured to open and close the gate, and the driving component is configured to drive the blocking member 21 to move along the first direction (in this embodiment, the gate is disposed on the wall of the first accommodating cavity, and the driving component and the blocking member 21 may both be disposed on the outer wall of the first accommodating cavity or the inner wall of the first accommodating cavity). When the blocking mechanism 2 is in a blocking state, the blocking piece 21 closes the gate, and the animal cannot enter the experiment area 12 from the experiment preparation area 11; when the blocking mechanism 2 is in the released state, the blocking member 21 opens the gate and the animal can enter the experimental zone 12 from the experimental preparation zone 11. For example, as shown in fig. 1, in the present embodiment, the blocking member 21 is a gate, and the gate faces the second direction, so that the structure of the blocking member 21 is relatively simple.
The blocking member 21 is driven by a driving assembly, specifically, as shown in fig. 1 and fig. 3, in this embodiment, the driving assembly is located on one side of the gate in the third direction, the driving assembly includes a first driving motor 22 and a first lead screw structure 23, the first driving motor 22 and the first lead screw structure 23 are both arranged along the first direction, a rotating shaft of the first driving motor 22 is connected with one end of a lead screw of the first lead screw structure 23, and a lead screw nut of the first lead screw structure 23 is connected with the blocking member 21 by a first connecting member 24, wherein the first direction, the second direction and the third direction intersect each other two by two (for example, in this embodiment, the first direction, the second direction and the third direction are respectively in the up-down direction, the front-back direction and the left-right direction), so that the structure of the driving assembly is simpler.
As shown in fig. 1 and 3, in the present embodiment, a driving mechanism 3 is provided on the apparatus main body 1, and the driving mechanism 3 is used for driving animals to move in the experimental area 12. At the end of an experiment, the animal can be driven back to the experiment preparation area 11 by the driving mechanism 3, and then the gate is closed, and the experiment is ended.
Specifically, as shown in fig. 1 and fig. 3, in the present embodiment, the driving mechanism 3 includes a push plate 31 and a push plate driving assembly, the push plate 31 is movably disposed in the second accommodating cavity along the second direction, and the orientation of the push plate 31 is the second direction; the push plate driving assembly is used for driving the push plate 31 to move along the second direction. The animals can be driven in the test area 12 during the test by means of a movable push plate 31. Wherein, the push plate 31 is arranged in a hollow way, so that the application of the prize is not influenced.
The push plate 31 is driven by the push plate driving assembly, specifically, as shown in fig. 1 and fig. 3, in this embodiment, the push plate driving assembly includes a second driving motor 32 and a second screw structure 33, the second driving motor 32 and the second screw structure 33 are both arranged along the second direction, a rotating shaft of the second driving motor 32 is connected with one end of a screw of the second screw structure 33, and a screw nut of the second screw structure 33 is connected with the push plate 31 by a second connecting piece, so that the structure of the push plate driving assembly is simpler.
The push plate driving assembly may be disposed on an inner side of the second accommodating cavity, or may be disposed on an outer side of the second accommodating cavity, specifically, as shown in fig. 1 and 3, in this embodiment, the push plate driving assembly is located on one side of the push plate 31 in the third direction and is disposed on an outer cavity wall of the second accommodating cavity, a sliding groove (not shown in the drawings) extending along the second direction is disposed through a cavity wall of the second accommodating cavity, a second connecting member (not shown in the drawings) is slidably mounted at the sliding groove, the push plate 31 and the push plate driving assembly are respectively connected to two ends of the second connecting member in the third direction, the push plate driving assembly is disposed on the outer side of the second accommodating cavity, and thus, a gap is not easily formed between the push plate 31 and the inner cavity wall of the second accommodating cavity.
As shown in fig. 2, a punishment mechanism 4 is provided on the apparatus main body 1, and the punishment mechanism 4 is used for giving punishment to animals in the experimental region 12. The punishment mechanism 4 is specifically configured to be related to a predetermined punishment event, for example, as shown in fig. 2, in this embodiment, the experimental region 12 has a carrying surface for carrying animals (in this embodiment, the second accommodating chamber is disposed in an upward opening manner, and a lower cavity wall of the second accommodating chamber forms the carrying surface), the punishment mechanism 4 includes an electric shock plate 41, and the electric shock plate 41 is disposed on the carrying surface near the reward application region 13. The punishment event is set behind the experimental zone 12, the punishment event is mainly the electric shock plate 41 of the experimental zone 12, the intensity of the current on the electric shock plate 41 can be adjusted according to the needs of the experiment, and whether the electric shock plate 41 applies the current or not can also be controlled through the presetting of the experiment.
As shown in fig. 1 and 3, the experiment controller 5 is disposed on the apparatus main body 1, and the blocking mechanism 2, the driving mechanism 3, and the punishment mechanism 4 are all electrically connected to the experiment controller 5. The blocking mechanism 2, the driving mechanism 3 and the punishing mechanism 4 can be controlled by an experimental controller 5.
The automatic experimental device 100 provided by the embodiment of the invention can realize the conversion of the position of the tested animal by automatically controlling the blocking mechanism 2 and the driving mechanism 3 without manual intervention; and the application of the reward and punishment is set before the experiment through the experiment controller 5, so that automatic multiple continuous experiments can be realized, the influence of manual intervention on the experiment result is reduced, the working intensity of experimenters is relieved, multiple groups of parallel experiments can be simultaneously implemented, and the difficulty and time of the experiment are reduced.
As shown in fig. 1 and fig. 3, in the present embodiment, the automated experiment device 100 further includes a warning light disposed on the device body 1 and electrically connected to the experiment controller 5, and the warning light includes a punishment warning light 51 and/or an experiment start warning light 52. The automated laboratory device 100 is designed with a light indicator, and when the laboratory starts, the laboratory start indicator 52 lights up to indicate that the animal enters the laboratory. In addition, a punishment prompting lamp 51 capable of being independently controlled is provided, when punishment exists, the punishment prompting lamp 51 can be simultaneously started, and the punishment prompting lamp 51 can also be independently controlled so as to research the reflective behavior of the animal.
The existing conditional position preference experimental device mostly adopts manual or video recording to record animal behaviors. In such animal experiments, the residence time and the passing speed of the animal in each area are the key data to be recorded in the experiment, but the recording precision of the time and the moving speed obtained by manual recording or video analysis is poor, and the labor cost is high, so as shown in fig. 1, in this embodiment, the automatic experimental apparatus 100 further includes a monitoring mechanism 6 disposed on the apparatus main body 1 and electrically connected to the experiment controller 5, and the monitoring mechanism 6 is used for monitoring the position and the moving speed of the animal in the experimental area 12. The automatic recording of the movement position and the movement speed of the animal in the automatic experimental device 100 in the experimental process can be realized through the monitoring mechanism 6, the error caused by artificial observation is avoided, the data can be exported for experimental analysis, and the accuracy and the reliability of the experiment are effectively improved.
Specifically, as shown in fig. 1 to 3, in the present embodiment, the second accommodating cavity is provided with a plurality of mounting holes arranged at intervals in the second direction, and the monitoring mechanism 6 includes a plurality of proximity switches 61 (the proximity switches 61 may be infrared proximity switches or the like, and the plurality of proximity switches 61 are usually arranged at equal intervals, for example, the monitoring mechanism 6 includes 16 infrared proximity switches at equal intervals, and the interval between two adjacent infrared proximity switches in the second direction is 6cm) respectively arranged at the plurality of mounting holes. The automatic experimental device 100 monitors the position and the movement speed of the animal by utilizing a group of equidistant proximity switches 61, and the experimental controller 5 can periodically acquire the state of each proximity switch 61 in the experimental process so as to judge the change of the position of the animal and calculate the movement speed of the animal by recording the time of the animal passing through two proximity switches 61. The experiment controller 5 can record the moving direction of the animal and the time of staying in each subarea of the automatic experiment device 100 according to the signals of the proximity switches 61, and provide raw data for subsequent experiment result analysis. The acquired animal motion data will be recorded in the FLASH of the experiment controller 5, and the experimenter can export the experiment data by using the usb disk after the experiment is finished.
As shown in fig. 3, in the present embodiment, the blocking mechanism 2 further includes a first limit switch 25 for limiting the blocking member 21 in the moving stroke of the blocking member 21. The driving mechanism 3 further comprises a second limit switch 34, and the second limit switch 34 is used for limiting the push plate 31 within the moving stroke of the push plate 31. As shown in fig. 3, the automated experimental apparatus 100 further includes a motor stroke controller 53, a first motor driver 54, a second motor driver 55, an interactive touch screen 7 and a power supply 8, all of which are electrically connected to the experimental controller 5. The experiment controller 5, the first driving motor 22, the first screw structure 23, the second driving motor 32, the second screw structure 33, the motor stroke controller 53, the first motor driver 54, the second motor driver 55, the interactive touch screen 7, the first limit switch 25, the second limit switch 34 and the power supply 8 form an automatic control system of the automatic experiment device 100.
As shown in fig. 4, the experiment controller 5 includes a central processing unit, and a storage unit, a clock unit, a data export unit, an experiment process control unit and an animal movement recording unit all electrically connected to the central processing unit, and the experiment controller 5 has functions of automatic experiment process control, real-time experiment data acquisition and the like. The experiment controller 5 adopts an ARM M3 kernel STM32F103 as a central processing unit; the storage unit adopts a mode of combining EEPROM and FLASH, the EEPROM adopts AT24CS16 to store the frequently modified setting parameters and other data of the system, and the FLASH adopts W25Q64 to store the collected experiment control process data and the experiment monitoring data; the experiment controller 5 adopts an RTC clock as a clock unit to obtain the current time through the RTC clock; the experiment controller 5 adopts a CH376 USB driving chip as a data export unit, so that export of experiment data to the USB flash disk is realized; the operating system of the experiment controller 5 adopts a uCOS-II real-time operating system, and the main functions of the experiment controller 5 are realized in a multi-task parallel mode; the experimental process control unit realizes automation and programmability of the experimental process by automatically controlling the mechanical structure and the stimulation applying device of the automatic experimental device 100, an experimenter can compile key elements in the experimental process according to experimental needs, and the experimental controller 5 realizes the automatic control of the experimental process according to time sequence logic or sensor feedback; the automatic experimental device 100 further provides an interactive touch screen 7 (the interactive touch screen 7 may be an LCD touch screen or the like) as an interpersonal interaction unit, and an experimenter can set an experimental process through the interactive touch screen 7.
The automatic experimental device 100 realizes the control of the experimental process through the experimental controller 5, and specifically, in the present embodiment, the control of the experimental process mainly includes the number of times of a set of experiments, the time length of each experiment, the time interval between two experiments, whether the punishment is applied and the intensity applied in each experiment, whether the start warning light 52 and the punishment warning light 51 of each experiment are turned on. The experimenter can design corresponding parameters through the interactive touch screen 7, and the experiment controller 5 can automatically execute the experiment process according to the setting of the experimenter.
The following briefly introduces the working principle of the automated experimental apparatus 100 with reference to the specific structure of the automated experimental apparatus 100 in this embodiment:
when the experiment is started, the experiment controller 5 sends a forward rotation instruction of the second screw structure 33 to the motor stroke controller 53, and the second screw structure 33 drives the push plate 31 to reach one side of the reward application area 13. After the push plate 31 is in place, the experiment controller 5 sends a forward rotation instruction of the first lead screw structure 23 to the motor stroke controller 53, the first lead screw structure 23 drives the gate to be opened, and the experiment starts. The automatic experimental device 100 performs an experiment once according to the experiment duration set by the experimenter, and when the experiment duration reaches the back, the experiment controller 5 sends a reverse rotation instruction of the second screw rod structure 33 to the motor stroke controller 53, and the second screw rod structure 33 drives the push plate 31 to drive the animal into the experiment preparation area 11 and reach one side of the experiment preparation area 11. After the push plate 31 is in place, the experiment controller 5 sends a reverse rotation instruction of the first lead screw structure 23 to the motor stroke controller 53, the first lead screw structure 23 drives the gate to be closed, and the experiment is finished. And a new experiment is started after the waiting time exceeds the two experiment intervals set by the experimenter.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (8)
1. An automated conditional positional preference class animal behavior testing apparatus, comprising:
the experiment device comprises a device main body, a detection device and a control device, wherein an experiment preparation area, an experiment area and a reward application area are formed in the device main body, and the experiment area is arranged between the experiment preparation area and the reward application area at intervals;
a blocking mechanism provided on the apparatus main body, the blocking mechanism having a blocking state of blocking the animal from entering the experiment area from the experiment preparation area, and a release state opposite to the blocking state;
the driving mechanism is arranged on the device main body and is used for driving animals to move in the experimental area;
a punishment mechanism arranged on the device body and used for applying punishment to the animals in the experimental area; and the number of the first and second groups,
the experiment controller is arranged on the device main body, and the blocking mechanism, the driving mechanism and the punishing mechanism are electrically connected with the experiment controller;
the device body is provided with a second accommodating cavity extending along a second direction, and the second accommodating cavity forms the experimental area; the driving mechanism comprises:
the push plate is movably arranged in the second accommodating cavity along the second direction, and the direction of the push plate is the second direction; and the number of the first and second groups,
the push plate driving assembly is used for driving the push plate to move along the second direction;
the push plate is arranged in a hollow manner; and/or the presence of a gas in the gas,
the push plate driving assembly is positioned on one side of the push plate in a third direction and is arranged on the outer cavity wall of the second accommodating cavity, a sliding groove extending along the second direction is arranged on the cavity wall of the second accommodating cavity in a penetrating mode, a second connecting piece is installed at the sliding groove in a sliding mode, two ends of the second connecting piece in the third direction are respectively connected with the push plate and the push plate driving assembly, and the second direction is intersected with the third direction; and/or the presence of a gas in the gas,
the push plate driving assembly comprises a second driving motor and a second lead screw structure, the second driving motor and the second lead screw structure are arranged along the second direction, a rotating shaft of the second driving motor is connected with one end of a lead screw of the second lead screw structure, and a lead screw nut of the second lead screw structure is connected with the push plate through a second connecting piece; and/or the presence of a gas in the gas,
the driving mechanism further comprises a second limit switch, and the second limit switch is used for limiting the push plate in the moving stroke of the push plate.
2. The automated conditional situational preference class animal behavioral testing apparatus according to claim 1, wherein the apparatus body is provided with a first housing chamber, a second housing chamber, and a third housing chamber, the first housing chamber, the second housing chamber, and the third housing chamber forming the test preparation zone, the test zone, and the reward application zone, respectively;
the first chamber that holds with the third holds the chamber and is to extend the setting along the first direction, the second holds the chamber and extends the setting for following the second direction, the first chamber that holds with the third holds the chamber and is located respectively the second holds the chamber and is in both sides in the second direction, the first chamber that holds with the third holds the chamber and is in same one end in the first direction communicates respectively the second holds the chamber and is in the both ends of second direction, wherein, the first direction with the second direction is crossing.
3. The automated conditional situational preference class animal behavior experimentation apparatus of claim 2 wherein one of the first housing chamber and the second housing chamber is provided with a gate in communication therewith for communicating the other through the gate;
the blocking mechanism comprises a blocking piece and a driving assembly, the blocking piece is movably arranged at the gate along the first direction, the blocking piece is used for opening and closing the gate, and the driving assembly is used for driving the blocking piece to move along the first direction.
4. The automated conditional situational preference class animal behavior experimentation apparatus of claim 3, wherein the drive assembly and the barrier are both disposed on an outer chamber wall of the first containment chamber; and/or the presence of a gas in the gas,
the driving assembly is located on one side of the gate in a third direction, the driving assembly comprises a first driving motor and a first lead screw structure, the first driving motor and the first lead screw structure are both arranged along the first direction, a rotating shaft of the first driving motor is connected with one end of a lead screw of the first lead screw structure, a lead screw nut of the first lead screw structure is connected with the blocking piece through a first connecting piece, and the first direction, the second direction and the third direction are intersected in pairs; and/or the presence of a gas in the gas,
the blocking piece is a gate, and the direction of the gate is the second direction; and/or the presence of a gas in the gas,
the blocking mechanism further comprises a first limit switch, and the first limit switch is used for limiting the blocking piece in the moving stroke of the blocking piece.
5. The automated conditional site-preference animal behavior experimental apparatus of any one of claims 1-4, wherein the experimental zone has a carrying surface for carrying animals, and the punishment mechanism comprises an electric shock plate disposed on the carrying surface at a position close to the reward application zone.
6. The automated conditional locus preference type animal behavior experiment device according to any one of claims 1 to 4, further comprising a warning lamp arranged on the device body and electrically connected with the experiment controller, wherein the warning lamp comprises a punishment warning lamp and/or an experiment start warning lamp.
7. The automated conditional situational preference class animal behavior assay device of any one of claims 1-4, further comprising a monitoring mechanism disposed on the device body and electrically connected to the assay controller, the monitoring mechanism configured to monitor the position and speed of movement of the animal within the assay area.
8. The automated conditional situational preference class animal behavior experimental apparatus of claim 7, wherein the apparatus body is provided with a second housing cavity extending in a second direction, the second housing cavity forming the experimental zone;
the second holds the chamber and runs through and is provided with a plurality of edges second direction interval arrangement mounting hole, monitoring mechanism including set up respectively in a plurality of proximity switch of a plurality of mounting hole department.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010711434.8A CN112005961B (en) | 2020-07-22 | 2020-07-22 | Automatic change condition position preference class animal behavior experimental apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010711434.8A CN112005961B (en) | 2020-07-22 | 2020-07-22 | Automatic change condition position preference class animal behavior experimental apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112005961A CN112005961A (en) | 2020-12-01 |
| CN112005961B true CN112005961B (en) | 2021-11-26 |
Family
ID=73499602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010711434.8A Active CN112005961B (en) | 2020-07-22 | 2020-07-22 | Automatic change condition position preference class animal behavior experimental apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112005961B (en) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090044761A1 (en) * | 2004-04-06 | 2009-02-19 | Chapin John K | Method and apparatus for teleoperation, guidance and odor detection training of a freely roaming animal through brain stimulation |
| US9497928B2 (en) * | 2009-06-08 | 2016-11-22 | Purdue Research Foundation | System for automating animal testing protocols |
| US20120234256A1 (en) * | 2009-09-28 | 2012-09-20 | Harte Steven E | Mechanical conflict device |
| CN106284234B (en) * | 2016-09-22 | 2018-05-01 | 安徽理工大学 | A kind of underwater headstock gear of gate and method for opening and closing that aid in fish migration to trace back |
| CN108077183B (en) * | 2018-01-29 | 2023-05-02 | 王存金 | Animal adventure behavior testing device and testing method thereof |
| CN110521617B (en) * | 2018-05-25 | 2022-06-17 | 中国科学院深圳先进技术研究院 | Animal behavior monitoring system |
| CN208597514U (en) * | 2018-06-05 | 2019-03-15 | 温州智权工业设计有限公司 | A kind of dog cage with Telescopic rain baffle board |
| CN110420010B (en) * | 2019-07-19 | 2022-03-18 | 中国科学院心理研究所 | Reward approaching behavior system |
-
2020
- 2020-07-22 CN CN202010711434.8A patent/CN112005961B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN112005961A (en) | 2020-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20200154682A1 (en) | Systems and methods for automated control of animal training and discrimination learning | |
| DE60011851T2 (en) | Door with safety lock on heater for baby warmer | |
| CN112005961B (en) | Automatic change condition position preference class animal behavior experimental apparatus | |
| US3489521A (en) | Automatic laboratory | |
| DE102018102966B4 (en) | Robotic system | |
| EP2440039A2 (en) | System for automating animal testing protocols | |
| DK0457861T4 (en) | sliding | |
| JP4944123B2 (en) | Analyzer for analyzing samples on test elements | |
| DE102020205418A1 (en) | Cleaning module, sample analyzer with cleaning module and cleaning process | |
| CN211268074U (en) | Sleep deprivation instrument and deprivation system | |
| JP2016041030A (en) | Experimental animal visual function evaluation device | |
| CN106153879A (en) | Microfluidic system and the diagnostic method thereof of medical diagnosis on disease is realized with activity tiny organism | |
| US5968015A (en) | Injector head for medical use | |
| WO2011038384A2 (en) | Mechanical conflict device | |
| CN110786250B (en) | Animal search memory behavioristics experimental device and experimental method | |
| CN203279635U (en) | Self-induction multi-track animal experiment treadmill | |
| JP2519893B2 (en) | Behavior analysis device for specimens such as animals | |
| CN110521617B (en) | Animal behavior monitoring system | |
| CN116186514A (en) | Control method of integrated device | |
| Sutton et al. | The effect of nontemporal information processing on time estimation in pigeons | |
| JP2008289450A (en) | Feeding system for animal raising, and system for animal raising | |
| CN104839043B (en) | A set of device for evaluating primate cognition and Motor execution function | |
| EP2991452A2 (en) | System for spatially resolved lighting control | |
| CN206952475U (en) | The escapement and feed mechanism of a kind of workpiece | |
| CN108077183B (en) | Animal adventure behavior testing device and testing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |