CN111991290A - Silver ion-containing pet deodorizing and antibacterial liquid - Google Patents

Silver ion-containing pet deodorizing and antibacterial liquid Download PDF

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Publication number
CN111991290A
CN111991290A CN202010916214.9A CN202010916214A CN111991290A CN 111991290 A CN111991290 A CN 111991290A CN 202010916214 A CN202010916214 A CN 202010916214A CN 111991290 A CN111991290 A CN 111991290A
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percent
silver ion
deodorant
antibacterial
silver
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江华初
李阳
林学智
黄惠先
陈鑫隆
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Private Customized Guangzhou Technology Co ltd
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Private Customized Guangzhou Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/01Deodorant compositions
    • A61L9/013Deodorant compositions containing animal or plant extracts, or vegetable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2209/00Aspects relating to disinfection, sterilisation or deodorisation of air
    • A61L2209/20Method-related aspects
    • A61L2209/22Treatment by sorption, e.g. absorption, adsorption, chemisorption, scrubbing, wet cleaning
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a deodorizing antibacterial liquid containing silver ions for pets, which comprises the following components in percentage by mass: 1 to 10 percent of glycerin, 0.1 to 2 percent of hexanediol, 1 to 10 percent of deodorant, 0.0005 to 0.2 percent of silver ion antibacterial agent and the balance of purified water. The invention can effectively kill Escherichia coli, staphylococcus aureus and Candida albicans, and has longer deodorization and antibacterial effects.

Description

Silver ion-containing pet deodorizing and antibacterial liquid
Technical Field
The invention relates to the technical field of pet supplies, in particular to a silver ion-containing deodorant antibacterial liquid for pets.
Background
As the age has developed, more and more people will choose to raise pets as part of their lives. The crowd for raising pets is more, and some problems follow; for example: the peculiar smell of the pet and the excrement of the pet is often unacceptable; many external sources of toxic and bacterial infections of cross-infectious diseases are probably transmitted to human beings through pets, and great potential safety hazards are brought to the health of people.
The deodorizing mechanism of common deodorizers achieves the aims of deodorization and sterilization through covering and decomposition, although the deodorizers can effectively eliminate odor molecules in an odor source and kill particle live bacteria through covering and decomposition, the deodorizing duration and the live bacteria killing capability of the deodorizers are not satisfactory and need to be improved.
Disclosure of Invention
Aiming at the defects of the prior art, the invention solves the technical problem of how to improve the deodorization duration and the live bacterium killing capability of the deodorant.
In order to solve the technical problems, the invention adopts the technical scheme that the deodorizing antibacterial liquid containing silver ions for the pet comprises the following components in percentage by mass:
1 to 10 percent of glycerin,
0.1 to 2 percent of hexanediol,
1 to 10 percent of deodorant,
0.0005 to 0.2 percent of silver ion antibacterial agent,
the balance being purified water.
The deodorant is persimmon tannin or a deodorant compound synthesized from persimmon tannin, and can wrap malodorous molecules such as mercaptan, sulfide, amine, other aldehydes, lower fatty acid and the like to form a permanent capsule so as to achieve the effect of eliminating peculiar smell.
The silver ion antibacterial agent is a silver ion aqueous solution, silver ions of the silver ion antibacterial agent directly exist in the aqueous solution, and the concentration of the silver ions in the silver ion aqueous solution is 5-2000 ppm.
Preferably, the deodorizing antibacterial liquid for the pet, which contains silver ions, comprises the following components in percentage by mass:
3 to 7 percent of glycerin,
0.5 to 1 percent of hexanediol,
3 to 7 percent of deodorant,
0.001 to 0.1 percent of silver ion antibacterial agent,
the balance being purified water.
The deodorant is persimmon tannin or a deodorant compound synthesized from persimmon tannin, and can wrap malodorous molecules such as mercaptan, sulfide, amine, other aldehydes, lower fatty acid and the like to form a permanent capsule so as to achieve the effect of eliminating peculiar smell.
The silver ion antibacterial agent is a silver ion aqueous solution, silver ions of the silver ion antibacterial agent directly exist in the aqueous solution, and the concentration of the silver ions in the silver ion aqueous solution is 10-1000 ppm.
Compared with the prior art, the invention can effectively kill Escherichia coli, staphylococcus aureus and Candida albicans, and has longer deodorization and antibacterial effects.
Detailed Description
The following examples are given to further illustrate the embodiments of the present invention, but are not intended to limit the invention.
Example 1:
the pet deodorizing antibacterial liquid containing silver ions comprises the following components in percentage by mass:
1 percent of glycerin,
2 percent of hexanediol,
1 percent of persimmon tannin,
0.0005% of silver ion aqueous solution, wherein the silver ion concentration is 5ppm,
the balance being purified water.
Example 2:
the pet deodorizing antibacterial liquid containing silver ions comprises the following components in percentage by mass:
3 percent of glycerin,
1 percent of hexanediol,
3 percent of persimmon tannin,
0.001% of silver ion aqueous solution, wherein the concentration of silver ions is 10ppm, and the balance is purified water.
Example 3:
the pet deodorizing antibacterial liquid containing silver ions comprises the following components in percentage by mass: 5 percent of glycerin,
0.7 percent of hexanediol,
5 percent of persimmon tannin,
0.005% of silver ion aqueous solution, wherein the concentration of silver ions is 50ppm, and the balance is purified water.
Example 4:
the pet deodorizing antibacterial liquid containing silver ions comprises the following components in percentage by mass: 7 percent of glycerin,
0.5 percent of hexanediol,
7 percent of persimmon tannin,
0.1% of silver ion aqueous solution, wherein the concentration of silver ions is 1000ppm, and the balance is purified water.
Example 5:
the pet deodorizing antibacterial liquid containing silver ions comprises the following components in percentage by mass:
10 percent of glycerin,
0.1 percent of hexanediol,
10 percent of persimmon tannin,
0.2% of silver ion aqueous solution, wherein the concentration of silver ions is 2000ppm,
the balance being purified water.
In the present invention, the silver ions have antibacterial effect through research of japanese scientists, and have the effect of killing most of bacteria or coronavirus when the concentration of the silver ions in the solution reaches 20ppm, and can inhibit or kill certain dose of escherichia coli, staphylococcus aureus, candida albicans, etc. when the concentration of the silver ions is 0.5 ppm. The antibacterial action mechanism of the silver ions is that the cell wall is broken by destroying the charge balance of the cell wall; destroying the active site of cell enzyme to make the cell lose growth and reproduction ability; meanwhile, the oral toxicology LD50 of the mouse carried out by the silver ion solution of 2000ppm is more than 2000mg/kg BW, and the silver ion solution belongs to a colorless, tasteless and practically nontoxic antibacterial agent.
To better illustrate the beneficial effects of the present invention, the following efficacy evaluation tests were performed:
(1) and (3) antibacterial property test:
the products of the invention were compared with commercially available products according to the test and analytical methods of disinfection specifications 2.1.11.3.3 (2002 edition) to obtain the following test results:
table 1:
Figure BDA0002665112390000061
and (4) conclusion: according to the test result table 1, the sterilization rate of the product of the invention on Escherichia coli, Staphylococcus aureus and Candida albicans reaches more than 90%, which is higher than the corresponding value of the product sold in the market, and the product has stronger antibacterial effect and can effectively kill Escherichia coli, Staphylococcus aureus and Candida albicans.
(2) And (3) testing the continuous antibacterial property:
the products of the invention were compared with commercially available products according to the test and analytical methods of disinfection specifications 2.1.11.3.3 (2002 edition) to obtain the following test results:
table 2:
Figure BDA0002665112390000071
Figure BDA0002665112390000081
according to the test results shown in Table 2, the sterilization rate of the product of the invention on Escherichia coli, Staphylococcus aureus and Candida albicans reaches more than 90%, which is higher than the corresponding value of the products sold in the market, and the product has strong antibacterial effect and can effectively kill Escherichia coli, Staphylococcus aureus and Candida albicans for 48 hours. (3) Malodor removing molecule test:
comparing the product of the invention with the product sold in the market, after the product of the invention and the product sold in the market are respectively acted in a treatment bottle containing the following malodorous molecules for 2 hours, the content of the malodorous molecules in the treatment bottle is tested, the removal rate is calculated, and the test results are obtained as the following table 3.
Table 3:
Figure BDA0002665112390000082
Figure BDA0002665112390000091
and (4) conclusion: according to the test results shown in Table 3, the removal rate of the malodorous substances such as sulfur dioxide, nitrogen dioxide, ammonia, formaldehyde, benzene, toluene, xylene, TVOC (total volatile organic compounds), hydrogen sulfide, methyl mercaptan, methyl sulfide, indole and the like reaches more than or equal to 70 percent, which is better than or equal to the corresponding value of the commercial products. (4) And (3) testing the deodorization effect:
the product of the invention is compared with products sold in the market, and 100 families with pets are divided into two groups for indoor deodorization effect comparison test.
The test method comprises the following steps: one group uses the commercial product, the other group uses the product of the invention, the deodorization antibacterial liquid is sprayed on the position with heavy pet odor, and the olfaction is evaluated in comparison at 1h, 2h, 4h and 8h, and the results are shown in the following table 4.
Table 4:
Figure BDA0002665112390000092
and (4) conclusion: according to the test results, table 3 shows that 100% of the test families considered satisfactory deodorizing effect at 1h using the product of the present invention; at 2h, 96% of test families considered that the deodorization effect was satisfactory; at 4h, 90% of the test families considered the deodorizing effect satisfactory; at 8h, 82% of tested families consider the deodorization effect to be satisfactory and better than the corresponding value of the products sold in the market.
(5) And (3) testing toxicity:
the second part 2.3.1 test and analytical methods according to the Disinfection Specification 2002 edition.
The test substance: the product is a tested sample, 5g of the sample is weighed, sterilized water is added to the sample to be constant volume of 20mL, and the mixture is uniformly mixed.
Experimental animals: animal species strains: SPF grade KM mice.
And (3) test environment: the ambient temperature is 22-25 ℃, and the relative humidity is 40-70%.
The test steps are as follows: prior to the experiment, the experimental animals were fasted overnight without restriction of drinking water. During the test, the weight of animals is weighed and randomly grouped, the tested sample is given once for oral contamination, the gastric lavage amount of each mouse is 0.2mL/10g of the weight, the dosage is 5000mg/kg & BW, and the fasting is 3-4h after the contamination. Each animal was individually and thoroughly recorded after the infection, and the experimental animals were observed for the manifestation of the toxicity and the death, after which they were carefully examined once a day, and the body weights were respectively measured on day 0 (D0), day 7 (D7) and day 14 (D14) of the administration. The observation period was 14 d. After the observation, the animals were sacrificed for gross anatomical examination and the results of the test are shown in table 5 below.
Table 5:
Figure BDA0002665112390000101
Figure BDA0002665112390000111
note: all tested animals did not show obvious toxic symptoms and death within the 14-day observation period.
And (4) conclusion: in thatUnder the test conditions, the test substance has acute oral toxicity LD on SPF KM mice50More than 5000mg/kg BW, is practically nontoxic.
In conclusion, compared with the prior art, the invention can effectively kill Escherichia coli, staphylococcus aureus and Candida albicans, and has longer deodorization and antibacterial effects.
The embodiments of the present invention have been described in detail with reference to the examples, but the present invention is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention.

Claims (5)

1. The deodorant antibacterial liquid for the pets, which contains silver ions, is characterized by comprising the following components in percentage by mass:
1 to 10 percent of glycerin,
0.1 to 2 percent of hexanediol,
1 to 10 percent of deodorant,
0.0005 to 0.2 percent of silver ion antibacterial agent,
the balance being purified water.
2. The deodorant and antibacterial liquid for pets according to claim 1, wherein the silver ion antibacterial agent is an aqueous silver ion solution, the silver ions are directly present in the aqueous solution, and the concentration of the silver ions in the aqueous silver ion solution is 5-2000 ppm.
3. The silver ion-containing deodorant and antibacterial liquid for pets according to claim 1, characterized by comprising the following components by mass percent:
3 to 7 percent of glycerin,
0.5 to 1 percent of hexanediol,
3 to 7 percent of deodorant,
0.001 to 0.1 percent of silver ion antibacterial agent,
the balance being purified water.
4. The deodorant and antibacterial liquid for pets according to claim 3, wherein the silver ion antibacterial agent is an aqueous silver ion solution, the silver ions are directly present in the aqueous solution, and the concentration of the silver ions in the aqueous silver ion solution is 10-1000 ppm.
5. The silver ion-containing pet deodorizing and antibacterial liquid according to claim 1 or 3, wherein the deodorant is persimmon tannin or a deodorizing compound synthesized from persimmon tannin.
CN202010916214.9A 2020-09-03 2020-09-03 Silver ion-containing pet deodorizing and antibacterial liquid Withdrawn CN111991290A (en)

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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010916214.9A CN111991290A (en) 2020-09-03 2020-09-03 Silver ion-containing pet deodorizing and antibacterial liquid

Publications (1)

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CN111991290A true CN111991290A (en) 2020-11-27

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Application publication date: 20201127